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Dissertations / Theses on the topic 'Vaccination'

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1

Brisson, Marc. "Economic evaluation of vaccination programmes : a special reference to varicella vaccination." Thesis, City University London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407544.

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2

Hamilton, Carly Anne. "Neonatal vaccination : role for innate immune cell interactions in BCG vaccination." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22079.

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Bovine tuberculosis (TB), caused by Mycobacterium bovis, is increasing in incidence in the United Kingdom and detailed knowledge of host-pathogen interactions in the natural host is essential to facilitate disease control. Vaccination of neonatal calves with Bacille Calmette Guerin (BCG) induces a significant level of protection from infection with M. bovis. Since neonatal vaccination of humans with BCG induces activation of natural killer (NK) cells, and neonatal calves have high circulating numbers of these cells, it is proposed that NK cells are important in the response to BCG. Furthermore
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3

Dannetun, Eva. "Reasons for non-vaccination /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-739-1/.

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4

Leach, Richard Jonathan. "Genetics of bovine vaccination." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5018.

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Infectious disease is an important issue for animal breeders, farmers and governments. Solutions to control infectious disease are needed and research focused on the genetic loci determining variation in immune-related traits has the potential to deliver solutions. The primary aim of this thesis is to discover regions of the bovine genome which influence the immune response post immunisation. To accomplish this two types of immunising agents, a Foot-and-Mouth Disease Virus (FMDV) peptide (FMDV15) and a commercial vaccine for Bovine Respiratory Syncytial Virus (BRSV), were used to immunise the
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5

Campbell, John P. "Behavioural adjuvants to vaccination." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/830/.

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This thesis investigated the effects of acute eccentric exercise on the immune response to vaccination in young humans. Study one investigated whether the efficacy of the eccentric exercise intervention was affected by manipulating the timings of exercise prior to influenza vaccination. Three exercise groups were vaccinated immediately, 6 hr or 48 hr after exercise and antibody responses at 28 days post-vaccination were compared to those from a resting control group. All participants exhibited robust antibody responses to the vaccine and no effect of exercise was observed; therefore, it was no
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6

Di, Genova Gianfranco. "Vaccination and immunological memory." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/63837/.

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Human subjects maintain long-term immunological memory against infective organisms but the mechanism is unclear. CD4+ T helper memory cells (Thmem) are pivotal in controlling humoral and cellular responses, therefore their longevity and response to vaccination are critical for maintenance of protective immunity. To probe the dynamics of the Thmem response to antigenic challenge, we investigated subjects following a booster injection with tetanus toxoid (TT). Expansion of TT-specific Thmem cells, and cytokine production, showed complex kinetics. Strikingly, parallel expansion and cytokine produ
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7

Montmartin, Philippe. "Tolérance de la vaccination anti-grippale : à propos d'une étude rétrospective sur 741 vaccinations, dans le département de la Loire." Saint-Etienne, 1994. http://www.theses.fr/1994STET6226.

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8

Sundberg, Mikael. "Misstro mot vaccination i modern kommunikation : Kvantitativ analys av Facebookgruppen "Stop Mandatory Vaccination"." Thesis, Högskolan i Gävle, Avdelningen för humaniora, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-30388.

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Syften med uppsatsen var att ta reda på hur folk som är en del av anti-vaccinationsrörelsen kommunicerar i sociala medier. Uppsatsen undersöker hur de kommunicerar i inlägg och kommentarer i en sluten grupp på Facebook. Med hjälp av ett kodschema så blev 97 inlägg analyserade och placerad i olika kategorier med olika variabler. Utifrån kodschemat blev flera tabeller skapade som visade den mest relevanta faktan. Utifrån den information, och med flera detaljerat beskriva exempel-inlägg, beskrivs den generella stämningen i gruppen och hur de talar med varandra. Resultatet blev att de kommunicerar
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9

Bravetti, Vincent Birgé Jacques. "Statut vaccinal diphtérie, tétanos, poliomyélite, coqueluche et hépatite B de l'adolescent et l'adulte jeune premier tour d'audit auprès de 49 médecins généralistes lorrains /." [S.l.] : [s.n.], 2007. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2007_BRAVETTI_VINCENT.pdf.

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10

Dulude, Alexandra. "CANCER PATIENT ATTITUDES TOWARDS INFLUENZA VACCINATION AND THE PREVALENCE OF VACCINATION IN CANCER PATIENTS." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/528169.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.<br>Introduction: Thousands of people die from influenza or its complications each year despite the fact that it is one of the few vaccine preventable diseases. Immunocompromised cancer patients are among the most vulnerable to this infection and flu‐related complications, and therefore vaccination is highly recommended in these patients; however, current vaccination rates and attitudes towards vaccination remain unknown. We hypothesize
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11

Bai, Fan. "Vaccination models in infectious diseases." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58346.

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Vaccination is the most effective method of preventing the spread of infectious diseases. In this thesis, we develop and apply mathematical models to study vaccination. The thesis consists of three main parts. Firstly, in deciding whether to be vaccinated before the outbreak of the epidemic, people need to consider the risk from vaccination and the probability of being infected. The decision of one individual is indirectly influenced by the decisions of all other individuals. Because the vaccine coverage levels are determined by all decisions of all individuals. We apply game theory to
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12

Gaucher, Denis. "DNA vaccination against Entamoeba histolytica." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82877.

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Invasive amebiasis, caused by the protozoan parasite Entamoeba histolytica, is one of the leading parasitic causes of mortality worldwide, and there are no vaccines available to control the disease. The heavy subunit of the E. histolytica Gal-lectin is regarded as a potential subunit vaccine candidate. A Th1 (cell-mediated) immune response is protective against invasive amebiasis, and DNA vaccination is a strategy to induce such a response against specific antigens. The objective of this study was to construct and test a Gal-lectin-based DNA vaccine against E. histolytica. DNA encoding
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13

Foulquier, Christine. "La vaccination par voie orale." Paris 5, 1996. http://www.theses.fr/1996PA05P179.

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14

Cranmer, Lee D. "Experimental vaccination against murine cytomegalovirus /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1996. http://wwwlib.umi.com/cr/ucsd/fullcit?p9714856.

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15

Ringard, Aurélia Ballereau Françoise. "Vaccination contre les papillomavirus humains." [S.l.] : [s.n.], 2008. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=51051.

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16

Badahdah, Almamoon. "Meningococcal Carriage, Disease and Vaccination." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21801.

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Invasive meningococcal disease (IMD) is caused by Neisseria meningitidis; a Gram-negative, aerobic encapsulated diplococcus that can cause large scale meningitis outbreaks. The risk of meningococcal carriage and disease is higher among particular age groups, certain community settings and travellers. The prevalence of invasive meningococcal disease peaks during infancy due to lack of immunity and again, to a lesser extent, in late adolescence/early adulthood due to increased social mixing. Closed and semi-closed community settings are also associated with high rates of meningococcal transmissi
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17

HUPPERT, PIERRE. "Les nouveautes en vaccination antirabique." Strasbourg 1, 1991. http://www.theses.fr/1991STR15019.

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18

Thomas, Whitney L. "Teen vaccination: what makes vaccination work and what keeps it from happening in your practice." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12653.

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Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States, and in women, infection by the virus is a major risk factor for developing cervical cancer. In 2006 the U.S. F
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19

King, Catherine. "Influenza and influenza vaccination: examining parental perspectives and practices to inform vaccination policy and programs." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18937.

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Influenza is a potentially serious disease, causing hospitalisations and deaths, particularly in children and the elderly. Traditionally immunisation efforts targeted the elderly and those at high risk from the disease. As awareness of the paediatric burden of influenza disease and potential population benefits of vaccinating children grew, immunisation efforts expanded, but coverage among children remains low. Expansion of influenza vaccine funding to include all Australian children is being considered, but there is little information about whether parents accept or support this. This thesis
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20

Edens, William Christopher. "Measles and polio vaccination using a microneedle patch to increase vaccination coverage in the developing world." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/52951.

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Despite the existence of effective vaccines for both diseases, measles and poliomyelitis still cause significant worldwide morbidity and mortality. The live-attenuated measles and inactivated polio vaccines are both given using a standard needle and syringe injection. This method of delivery poses many problems for large-scale vaccination campaigns. Microneedles are micron-scale needles which have the potential to overcome many of these hurdles. In the first study, we showed that the measles vaccine could be successfully incorporated into a solid, metal microneedle system which induced potent
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21

Reveneau, Nathalie. "Vaccination par voie muqueuse : utilisation de Lactobacillus plantarum et Bordetella pertussis comme vecteurs vivants de vaccination." Lille 1, 2001. https://pepite-depot.univ-lille.fr/LIBRE/Th_Num/2001/50376-2001-155.pdf.

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22

Reveneau, Nathalie Locht Camille Mercenier Annick. "Vaccination par voie muqueuse utilisation de Lactobacillus plantarum et Bordetella pertussis comme vecteurs vivants de vaccination /." [S.l.] : [s.n.], 2001. http://www.univ-lille1.fr/bustl-grisemine/pdf/extheses/50376-2001-155-156.pdf.

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23

Fleeton, Marina N. "Genetic vaccination against acute viral disease /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3811-3/.

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24

Joseph, Karen T. "Vaccination in a Private Pediatric Practice." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/iph_theses/214.

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Background: Following the publication of Andrew Wakefield’s article claiming a link between Autism and the MMR vaccine in 1998, the U.K. and U.S. experienced a decline in vaccination rates. Combating the anti-vaccine messages highlighted by the media are the medical providers, who are consistently reported as an influential source of information for parental vaccine decision making. Despite efforts of the medical and public health community, some developed countries have seen a resurgence of vaccine preventable diseases. Purpose: This study seeks to examine parental vaccination concern in a pr
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25

Song, Keli 1955. "DNA-based vaccination against carcinoembryonic antigen." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36837.

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DNA vaccination is based on in vivo delivery of plasmids encoding an antigen, leading to antigen synthesis and specific immunity. This technology is still in its infancy but has advantages over conventional vaccination, such as the stimulation of all arms of the immune response, i.e., humoral immunity, T-helper (17h) cells and cytotoxic T lymphocytes (CTLs). We studied DNA vaccination against human carcinoembryonic antigen (CEA) in mice. Our hypothesis was that codelivery of cytokine- and CEA-encoding plasmids could regulate responses, and allow polarization of Th responses to either type 1 (T
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26

Krashias, George. "Adjuvant for vaccination against HIV-1." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531970.

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27

Jennings, Nicola. "Therapeutic DNA vaccination in follicular lymphoma." Thesis, Open University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437323.

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28

King, Catherine Anne. "Idiotypic vaccination against B cell tumours." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241861.

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29

Mamani, Hamed. "Supply chain coordination and influenza vaccination." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45944.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Sloan School of Management, Operations Research Center, 2008.<br>Includes bibliographical references (p. 125-129).<br>Annual influenza outbreaks incur great expenses in both human and monetary terms, and billions of dollars are being allocated for influenza pandemic preparedness in an attempt to avert even greater potential losses. Vaccination is a primary weapon for fighting influenza outbreaks. The influenza vaccine supply chain has characteristics that resemble the Newsvendor problem, but possesses several characteristics that distingu
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30

Deschênes, Elaine. "Vaccination à l'ADN contre Staphylococcus Aureus." Mémoire, Université de Sherbrooke, 2004. http://savoirs.usherbrooke.ca/handle/11143/4640.

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Staphylococcus aureus est une bactérie qui possède un potentiel virulent très élevé. Elle cause plusieurs types d’infections telle que des septicémies, des endocardites, et des mammites. La mammite bovine à Staphylococcus aureus est une infection très affligeante pour les animaux et les producteurs laitiers touchés. Ses nombreux facteurs de virulence permettent à la bactérie d’infecter les glandes mammaires des animaux en lactation. Il n’existe toujours pas de vaccins efficaces pour combattre ou prévenir les infections à Staphylococcus aureus. Il est donc primordial de trouver de nouvelles app
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31

Miller, Julie A. "Factors Influencing Influenza Vaccination of Children." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1377872672.

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32

Brown, Katrina Fiona. "Behavioural determinants of parents’ vaccination decisions." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6372.

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Childhood immunisation effectively protects personal and public health, but a sizeable minority of parents actively reject vaccines for their children. This Thesis explores how parents decide whether to have their children immunised, in order to inform efforts to improve immunisation uptake. A consistent profile of beliefs relating to vaccine rejection emerged across a systematic review of existing evidence, a semi-structured interview study (n=24), and two evidence-based questionnaire studies (n=900), which all focused on the measles, mumps and rubella (MMR) vaccine. Vaccine-rejecting parents
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33

Lefèvre, Antoine Fisch Alain. "Vaccination intradermique historique, présent et avenir /." Créteil : Université de Paris-Val-de-Marne, 2007. http://doxa.scd.univ-paris12.fr:80/theses/th0252424.pdf.

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34

Houle, Kim Cranney. "Vaccination Perceptions and Barriers of School Employees: A Pilot Study." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/3769.

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Schools are group settings where vaccine-preventable diseases can spread quickly, especially if vaccination rates are suboptimal. Vaccination of school children has been the subject of many studies; however, data are lacking regarding the vaccination status, vaccination perceptions, and potential barriers to vaccination for school employees. Method: A questionnaire was developed to measure school employees' perceptions,awareness of current vaccination status, and potential barriers to vaccinations. This study included a convenience sample of 277 employees from a small urban school district loc
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35

Lau, Hiu-wan Leonia, and 劉曉蘊. "Indirect benefit of vaccinating children to protect the community frominfluenza." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48423919.

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Background Influenza causes annual, worldwide epidemics of respiratory disease that affects all segments of the population. Mass vaccination of healthy children, who are playing an important role in the transmission of influenza, is promoted to be a complementary approach in prevention and control of influenza. However, lack of published systemic review evidencing the indirect protection of vaccinating healthy children makes the implementation under uncertainty. Method A systemic review was conducted by computerized bibliographic searches in PubMed and the Cochrane Library identifying
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36

Thornton, Eli Gary. "Rural School Employees' Awareness and Perceptions of Adult Vaccinations: A District-Wide Study." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/3556.

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As key members of the school environment, it is important for school employees to be vaccinated. Employees are in direct contact with children in close quarters for long periods of time and such an environment can easily serve as an outbreak center for vaccine-preventable communicable diseases such as measles. Despite the fact that most school employees believe vaccines are safe and effective and many school employees report they are up-to-date with their vaccines, a closer examination reveals discrepancy between belief and behavior. As a vaccine advocate, the school nurse can be influential i
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37

Bernhardt, Gina Leanne. "Evaluating measles vaccination coverage in high incidence areas of the Western Cape Province, following the mass vaccination campaign." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/6020.

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Includes abstract.<br>Includes bibliographical references.<br>Measles virus is known to be one of the most contagious of infectious agents and despite considerable progress towards elimination, a number of Sub-Saharan African countries experienced epidemics in 2009-2011, including South Africa, in which there were over 18 000 confirmed cases. The South African measles vaccination programme started in 1975 with 1 dose schedule, and from 1996-8 has followed the World Health Organization-United Nations Children’s Fund strategy. This includes a 2 dose routine vaccination schedule for children at 9
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38

Vergara, Alert Júlia. "Immune response to influenza infection and vaccination." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/98472.

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Els virus de la influença tipus A (VIA) són patògens zoonòtics que poden infectar un ampli nombre d’hostes incloent-hi les aus, els porcs i els homes, entre altres. Anualment es documenten milions d’infeccions en humans causades per virus de la influença estacionals. Les pandemies causades pel virus influença també tenen una elevada repercussió pel que fa a la sanitat i l’economia. Tot i que determinats subtipus de VIA s’adapten millor en espècies d’aus que en humans, hi ha hagut casos d’infeccions en humans per virus de la influença de tipus aviars. La susceptibilitat dels porcs per infectar-
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39

Håkansson, Johanna. "Vaccination mot Humant Papillomvirus - vem bör vaccineras?" Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-30748.

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Background: Infection with Human Papillomavirus, HPV, is one of the world's most common sexual transmitted infections. The virus causes genital warts (condyloma) but certain virus types can cause cancer. The most common cancer type caused by the virus is cancer of the cervix. Nowadays there is a screening program for women between 23 and 60 years of age where Pap smears of the cervix is taken to discover abnormalities at an early stage. Cervical cancer is very common all over the world and this screening program saves many lives, but not in the less developed countries since the screening prog
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40

Gokhale, Kimaya. "Why are HPV Vaccination Rates So Low?" Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/scripps_theses/1098.

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This thesis attempts to apply the theory of rational disease dynamics to the human papillomavirus by testing whether HPV vaccinations are prevalence elastic. A prevalence elastic relationship suggests that HPV vaccination rates respond positively to increasing prevalence rates of cervical cancer. Prevalence rates are measured both by incidence rates of cervical cancer and by mortality rates of cervical cancer. Data from the NIS-Teen Survey as well as data from the United States Cancer Statistics branch of the Centers for Disease Controls are used to construct a linear regression that controls
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41

Morgosh, Kelsey. "The Anti-Vaccination Movement: Past and Present." The University of Arizona, 2015. http://hdl.handle.net/10150/626590.

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42

Renberg, Erika. "Nyttan och risker medHPV-vaccination : En litteraturstudie." Thesis, Umeå universitet, Farmakologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-146531.

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43

Lee, Christie. "DNA vaccination confers protection against coxsackieviral myocarditis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0020/MQ54140.pdf.

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44

Lobell, Anna. "Suppressive DNA vaccination in experimental autoimmune encephalomyelitis /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3782-6/.

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45

Noggle, Richard Brendan. "Adolescent Knowledge, Attitudes, and Beliefs toward Vaccination." Digital Archive @ GSU, 2007. http://digitalarchive.gsu.edu/iph_theses/31.

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Vaccination, one of public health’s greatest disease prevention tools, is broadening to focus on adolescents. Now that there are more vaccines targeted specifically for adolescents, it is time to give more focus to vaccine delivery in this population. This research will increase the knowledge base to support informed changes in adolescent vaccine delivery by identifying knowledge and attitudes of adolescents toward vaccination within the context of barriers and solutions. Perceived susceptibility to disease, benefits and barriers to vaccination and other constructs were collected through a sur
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46

Midgley, Claire Michelle. "Immune responses to smallpox vaccination in humans." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444465.

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47

Lindsay, Ross William Black. "Characterisation of lymphocyte migration following DNA vaccination." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444944/.

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Infection with influenza virus generally produces an immune response in immunocompetent individuals that will protect from further infection of the same strain of virus. The experiments carried out in this study were designed to identify correlates of protection induced by primary experimental influenza virus infection and to compare to/and assess Particle Mediated Immunotherapeutic Delivery (PMID) as a method of DNA immunisation. Initial experiments characterised the protective immune response observed following intranasal influenza virus infection with regard to the humoral and cellular resp
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48

Yao, Mianzhi, and 姚绵志. "Human swine influenza vaccination in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45175093.

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49

Dyke, Rebecca Jane. "Idiotypic vaccination against a B-cell lymphoma." Thesis, University of Southampton, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315961.

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50

Kay, Alison. "Plasmid fermentation for gene therapy and vaccination." Thesis, University College London (University of London), 2004. http://discovery.ucl.ac.uk/1446856/.

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Plasmid-based gene therapy and vaccination require the production of purified plasmid DNA. There is a current understanding that supercoiled plasmid DNA is the best form for administration and FDA guidelines state that a specification for the minimum level of supercoiled plasmid DNA, in the final product, should be made. Currently, plasmids of 10 kb or smaller are being used in gene therapy trials, but if plasmid-based vaccination is to become a reality then much larger plasmids, with the ability to carry multi-variant genes, will be required, this raises questions of feasibility of production
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