Academic literature on the topic 'Vagina'
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Journal articles on the topic "Vagina"
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Yllera, María del Mar, Diana Alonso-Peñarando, and Matilde Lombardero. "Gross Anatomy of the Female Reproductive System of Sugar Gliders (Petaurus breviceps)." Animals 13, no. 14 (2023): 2377. http://dx.doi.org/10.3390/ani13142377.
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We dissected carcasses of eight mature females, both parous and non-parous specimens, to study the macroscopic anatomy of the female reproductive system in the sugar glider. The genital system includes double organs, namely the right and left ones, which are completely separated. It includes two ovaries, two oviducts, two uteri and a vaginal complex. The uteri are fusiform-shaped and lack horns. The vaginal complex includes two lateral vaginae and a median vagina, also called the ‘birth canal’. The cranial end of both lateral vaginae partially fuses, forming an expansion named the vaginal sinus, which is divided into two parts by a longitudinal septum, one for each vagina, where the ipsilateral uterine cervix opens. The caudal end of the lateral vaginae opens into a medial and impar duct: the urogenital sinus that serves as a common passage for the reproductive and urinary systems. In non-pregnant females, only the lateral vaginae are present. In pregnant and recently parous females, a short median vagina extends from the caudal wall of the vaginal sinus to the cranial end of the urogenital sinus. In the ventral wall of this sinus, next to its caudal opening, there is a forked clitoris.
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Kozarski, Jefta, Svetlana Vesanovic, and Zoran Bogdanovic. "Anatomic and histological characteristics of vagina reconstructed by McIndoe method." Vojnosanitetski pregled 66, no. 2 (2009): 107–12. http://dx.doi.org/10.2298/vsp0902107k.
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Background/Aim. Congenital absence of vagina is known from ancient times of Greek. According to the literature data, incidence is 1/4 000 to 1/20 000. Treatment of this anomaly includes non-operative and operative procedures. McIndoe procedure uses split skin graft by Thiersch. The aim of this study was to establish anatomic and histological characteristics of vagina reconstructed by McIndoe method in Mayer K?ster-Rockitansky Hauser (MKRH) syndrome and compare them with normal vagina. Methods. The study included 21 patients of 18 and more years with congenital anomaly known as aplasio vaginae within the Mayer K?ster-Rockitansky Hauser syndrome. The patients were operated on by the plastic surgeon using the McIndoe method. The study was a retrospective review of the data from the history of the disease, objective and gynecological examination and cytological analysis of native preparations of vaginal stain (Papanicolau). Comparatively, 21 females of 18 and more years with normal vaginas were also studied. All the subjects were divided into the groups R (reconstructed) and C (control) and the subgroups according to age up to 30 years (1 R, 1C), from 30 to 50 (2R, 2C), and over 50 (3R, 3C). Statistical data processing was performed by using the Student's t-test and Mann-Writney U-test. A value of p < 0.05 was considered statistically significant. Results. The results show that there are differences in the depth and the wideness of reconstructed vagina, but the obtained values are still in the range of normal ones. Cytological differences between a reconstructed and the normal vagina were found. Conclusion. A reconstructed vagina is smaller than the normal one regarding depth and width, but within the range of normal values. A split skin graft used in the reconstruction, keeps its own cytological, i.e. histological and, so, biological characteristics.
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Nazneen, Most Afroza, Tania Afrin Tisha, and Summi Leonard Keya. "Reconstruction of Vagina with Bilateral Pudendal Thigh Flap: A Solution for Atresia/ Agenesis of Vagina." TAJ: Journal of Teachers Association 36, no. 2 (2023): 11–16. http://dx.doi.org/10.3329/taj.v36i2.71252.
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Reconstruction of vagina is a technically challenging surgery. The aim is to create a functionally and aesthetically satisfactory neovagina in a way that will be reliable and suitable for most atients. Use of bilateral udendal thigh fla to create a neovagina may overthrow the conventional methods as there is no necessity for osto erative dilation or vaginal intercourse to maintain adequate vaginal length and diameter. Vaginal reconstruction was done with bilateral udendal thigh fla s, in seven atients with vaginal agenesis, during 2 years, from July 2021 to June 2023. This method of vagino lasty is sim le, safe, and reliable and has shown satisfactory functional and cosmetic results. The reconstructed vagina has a natural angle and is sensate in its lower art. No osto erative stenting or dilatation is required. The donor site can be closed rimarily and the scar is well hidden in the groin crease. TAJ 2023; 36: No-2: 11-16
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Bunster, Eduardo, Enrique López, and José Cano. "Tratamiento de las aplasias, atresias e hipoplasias vaginales con falos acrílicos." Revista Peruana de Ginecología y Obstetricia 4, no. 2 (2015): 79–89. http://dx.doi.org/10.31403/rpgo.v4i1168.
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Consideramos brevemente nueve casos de pacientes operadas por defectos congénitos o adquiridos de la vagina en que se usaron falos acrílicos para mantener el lumen vaginal. En tres casos se usó el procedimiento de Kirschner-Wagner para crear neo-vaginas. En algunas pacientes se asoció a la intervención quirúrgica la administración de cortisona para disminuir la tendencia natural a la retracción de las paredes vaginales, de estrógenos y de vitaminas A para activar la nutrición y cicatrización de la mucosa vaginal o de los injertos de Thiersh colocados en la neo-vagina. La mortalidad ha sido nula y la morbilidad escasa y de poca importancia.
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Parr, Earl L., and Margaret B. Parr. "Immunoglobulin G, Plasma Cells, and Lymphocytes in the Murine Vagina after Vaginal or Parenteral Immunization with Attenuated Herpes Simplex Virus Type 2." Journal of Virology 72, no. 6 (1998): 5137–45. http://dx.doi.org/10.1128/jvi.72.6.5137-5145.1998.
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ABSTRACT This investigation evaluated immunity to vaginal herpes simplex virus type 2 (HSV-2) infection after local or parenteral immunization with attenuated HSV-2. Vaginal immunization induced sterilizing immunity against challenge with a high dose of wild-type virus, whereas parenteral immunizations protected against neurologic disease but did not entirely prevent infection of the vagina. Vaginal immunization caused 86- and 31-fold increases in the numbers of immunoglobulin G (IgG) plasma cells in the vagina at 6 weeks and 10 months after immunization, whereas parenteral immunizations did not increase plasma cell numbers in the vagina. Vaginal secretion/serum titer ratios and specific antibody activities in vaginal secretions and serum indicated that IgG viral antibody was produced in the vagina and released into vaginal secretions at 6 weeks and 10 months after vaginal immunization but not after parenteral immunizations. In contrast to the case for plasma cells, the numbers of T and B lymphocytes in the vagina were similar in vaginally and parenterally immunized mice. Also, lymphocyte numbers in the vagina were markedly but similarly increased by vaginal challenge with HSV-2 in both vaginally and parenterally immunized mice. Lymphocyte recruitment to the vagina after virus challenge appeared to involve memory lymphocytes, because it was not observed in nonimmunized mice. Thus, local vaginal immunization with attenuated HSV-2 increased the number of IgG plasma cells in the vagina and increased vaginal secretion/serum titer ratios to 3.0- to 4.7-fold higher than in parenterally immunized groups but caused little if any selective homing of T and B lymphocytes to the vagina.
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Gruzdev, V. "Stopping postpartum hemorrhage according to Henkel." Kazan medical journal 20, no. 3 (2021): 325. http://dx.doi.org/10.17816/kazmj76486.
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According to Zrmmermann's (ref. Zentr. F. Gyn, 1923, No. 26), the technique of this method is as follows: the bladder is emptied by catheterization; the vagina is opened with anterior and posterior spoon-shaped mirrors, the vaginal part is captured with bullet forceps and is brought down from the introitus vaginae; then the vaginal part is pulled to one side, and the wall of the vagina to the other, with the help of a lateral mirror, and the parametrium is strained; after taking the Museau forceps, the doctor applies them, sticking in the sleeve wall as high as possible, onto the uterine rib and squeezes; the same is done on the other side.
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Betova, Tatyana, Radoslav Trifonov, Savelina Popovska, et al. "Primary Vaginal Mucinous Adenocarcinoma of Intestinal Type—Clinical, Radiological and Morphological Aspects." Medicina 60, no. 4 (2024): 525. http://dx.doi.org/10.3390/medicina60040525.
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Background and Objectives: Neoplasms of the vagina are rare and account for 1–2% of all tumors of the female reproductive system. Primary neoplasms of the vagina are most often carcinomas originating from squamous or glandular epithelium. Of the primary glandular tumors, clear cell, endometrioid, and serous adenocarcinomas are the most common types, while mucinous and mesonephric types are very rare. Mucinous adenocarcinoma is histologically subclassified into endocervical and intestinal types. We add to the existing literature another case of an extremely rare gynecological neoplasm—primary vaginal mucinous adenocarcinoma (PVMAC) intestinal type associated with vaginal villous adenoma with high-grade dysplasia. We discuss the clinical, radiological and morphological features of this rare entity. Materials and Methods: We report a case of a 59-year-old woman with PVMAC intestinal type associated with vaginal villous adenoma with high-grade dysplasia. The patient was evaluated with a gynecological exam, and biopsy, curettage and tumor excision were performed. The positron emission tomography-computed tomography (PET/CT) scan, at the level of the pelvis, supported the primary location of the disease. Histological and immunohistochemical methods were applied. Results: The gynecological examination of the vagina revealed an exophytic polypoid mass with a diameter of 3 cm, located on the posterior wall, in the area of introitus vaginae. The PET/CT scan revealed a hypermetabolic malignant formation involving the vagina and anal canal, without evidence of pelvic and inguinal lymphadenopathy, and also, it excluded disease at sites other than the vagina. The histological and immunohistochemical investigations, as well as the clinical and radiological data, lent support to the diagnosis “primary vaginal mucinous adenocarcinoma intestinal type”. Conclusions: PVMAC intestinal type is a rare gynecological pathology, which presents a serious challenge for oncogynecologists, radiologists and pathologists.
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Ali Adwal Ali, Khalida M. Amin, Emil N. AZZO, and Ayla K. Kahya. "Absent vagina a description of cases with varied ages, presentations and reconstructions." International Journal of Research in Pharmaceutical Sciences 10, no. 3 (2019): 1741–45. http://dx.doi.org/10.26452/ijrps.v10i3.1365.
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The aim is to describe cases of vaginal agenesis of varied ages presentations and managements and report the outcome of interventions regarding restoration of continuity of reproductive tract and normal sexual activity. A prospective descriptive case series study. Five female patients with vaginal agenesis were recruited from November 2005 to November 2016. Three were adolescents and had a functioning uterus. Three patients underwent vaginoplasty using McIndoe method, one had vagino-vaginal anastomosis, and the other had hysterectomy to remove source of menstruation. Age ranged from 12 to 24 years. The outcome of vaginoplasties to the 2 young females and to one of the adolescent girls was adequate vagina, whereas the other 2 adolescent girls had failed redo vaginoplasty and ended with a patent narrowed vagina in one and a closed vagina in the other which required a hysterectomy. On Follow up (range 5 - 42 months) 2 of the adolescent’s girls had regular menstruation with no pain and pelvic collection, while the third one had amenorrhoea following a hysterectomy. The 3 patients who had successful vaginoplasty got married and enjoyed satisfactory intercourse. Patients with absent vagina presents at variable ages depending on whether a functioning uterus is present or not. The success of vaginoplasty is less when it has to be done in adolescence than when it is done in adulthood when patient is grown-up. Best outcomes require accumulative experience, ideally with the aid of doctors of other specialties.
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Rasad, Siti Darodjah, and Rangga Setiawan. "Cytological Characteristics of Mucose Cell and Vaginal Temperature and pH During Estrous Cycle in Local Sheep." ANIMAL PRODUCTION 19, no. 1 (2017): 21. http://dx.doi.org/10.20884/1.jap.2017.19.1.584.
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Aim of this study was to examine the characteristics cytology of mucous cell-,temperature- and pH vagina during estrous cycle in local sheep. 31local sheep were synchronized with vaginal sponge consist of 20 mg progesterone hormone before carried out observations of cytology of cells from the vaginal mucose through vaginal swabs, temperature and pH of the vagina. Vaginal swabs were collected daily at 7 am for a weeks.Vaginal temperature and pH measurement is carried out twice a day, at 07.00 am and 15.00 pm for a weeks after vaginal swabs. Smears of the swab were then prepared on glass slide and they were stained with Giemsa. Vaginal epithelial cells; Parabasal, intermediate and superficial cells were counted and their percentages during pro-estrous, estrous and di-estrous were determined. Di-estrous was characterized by the absent of superficial cells in the epithelial vagina. Pro-estrous was characterized by the increasing progressively of intermediate/superficial cells in epithelial vagina, whereas estrous was characterized by the presence of superficial/cornification cells in most epithelial vagina. Based on the dominance of superficial cell, the number of sheep identified as estrous is highest on third day, with 52%. Observation on vaginal temperature also resulting that the highest temperature values obtained on the third day of 39,08±0.28°C. It could be effected of the vaginal pH during the observation. Underthe influence ofestrogen, the epithelial vaginalcellssynthesizeand accumulateglycogenin large quantitiesdepositedin the lumen ofvagina. Vaginal bacteriametabolizethe glycogenformlactic acid, which causesvaginal pHis low.The pH conditions prevent from pathogenic microorganisms and fungi. Increased estrogenal so cause cell proliferation through the thickening of the epithelium lining of the vagina so that the cells differentiate.Increasing of glycogenin the superficial cells, and ceratin cells found in the cytoplasm of cells, as well as acidic pH in the lumen vagina causing changes in the chemical composition of each cell (Zaid, 2011).It can be concluded that during estrous phase, cytology of vaginal mucose cell is dominated by superficial cell and vaginal temperature is increasing as well as pH of vagina.
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Park, Sung-Ho, Eun Sil Lee, Sung Taek Park, et al. "Efficacy and Safety of MED-01 Probiotics on Vaginal Health: A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial." Nutrients 15, no. 2 (2023): 331. http://dx.doi.org/10.3390/nu15020331.
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Bacterial vaginosis (BV) is the most common disease in women of childbearing age and is caused by the growth of abnormal microbiota in the vagina. Probiotic consumption can be an effective alternative treatment to preserve or improve vaginal health. In the present study, MED-01, a complex of five strains of probiotic candidates isolated from the vagina of Korean women, was used. This study was designed as a 12-week, randomized, multicenter, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of MED-01 on vaginal health. A total of 101 reproductive-aged women with a Nugent score of 4–6 took MED-01 (5.0 × 109 CFU) or a placebo once a day, and 76 participants completed the procedure. MED-01 significantly reduced the Nugent score compared with the placebo. Quantitative PCR analysis confirmed that Lactobacillus plantarum was significantly increased in the vagina, whereas harmful bacteria such as Mobiluncus spp., Gardnerella vaginalis, and Atopobium vaginae were suppressed after 12 weeks of MED-01 ingestion. No adverse events to the test food supplements were observed in the participants. These results confirmed that MED-01 can be used as a probiotic for treating BV, as it improves the vaginal microbiota.
Dissertations / Theses on the topic "Vagina"
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Sjöberg, Inga. "The vagina : morphological, functional and ecological aspects." Doctoral thesis, Umeå universitet, Obstetrik och gynekologi, 1991. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100564.
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The vagina is one organ of the body which has not been studied exhaustively. Moreover, most of the studies found in the contemporary literature have been performed on women affected by a variety of genital diseases. In the present study the vaginal epithelium was examined with a histological method, morphometry, whereby cyclical changes related to hormonal variation during the menstrual cycle were demonstrated. Determination of the quantity of estrogen receptors in the vaginal epithelium on two occasions during the menstrual cycle revealed a significantly greater number in the follicular than in the luteal phase. The results of these studies indicate the presence of a menstrual variation in the vaginal epithelium comparable to that in the endometrium. Phenoxymethylpenicillin (pcV) was used as a marker substance to study the dynamics of the transport mechanisms into the vagina. PcV was found to accumulate in the vaginal fluid and high concentrations persisted for a long period of time. In hysterectomized women, the appearance of pcV in the vaginal fluid followed the same pattern. Consequently, the substance is transported through the vaginal wall and need not enter with the secretions from the internal genitalia. The greatest concentration of pcV was in the distal portion of the vagina, possibly due to the specific internal circulation of fluid within the vagina. Bacterial vaginosis as an example of an ‘ecological disease’ has been studied with regard to the formation of endotoxin, a constituent of the cell wall of Gram- negative bacteria. Large amounts of endotoxin were found and the clinical implication of this finding has been pointed out. Furthermore, the influence of pcV on the vaginal microbial flora of healthy women has been investigated. A change from a situation with predominance of lactobacilli to the appearance of Gram-negative rods was observed. In one of the women the lactobacilli disappeared completely and were replaced by E. coliand high levels of endotoxin in the vaginal fluid were found. This study demonstrates the complexity of the ecological balance of the vaginal microbial flora and illustrates the difficulty of defining a ‘normal’ vaginal condition. Is there any unquestionable state of ‘normality’ even in a healthy woman free from symptoms of genital disease?<br><p>S. 1-22: sammanfattning, s. 25-64: 6 uppsatser</p><br>digitalisering@umu
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Braun, Virginia. "The vagina : an analysis." Thesis, Loughborough University, 2000. https://dspace.lboro.ac.uk/2134/7539.
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The vagina is frequently represented in talk, texts, and imagery, giving us a range of sociocultural meanings, but at the same time, is still taboo - a word that is difficult to say, and a topic that is hard to talk about. My research aims to demarcate and explore the meanings given to the vagina in western culture, and to examine women's accounts of their personal meanings and experiences in relation to these socio-cultural representations. Taking a feminist social constructionist approach, I move beyond the notion of a natural, pre-social body to a conceptual isation of bodies deeply embedded in the socio-cultural, and assume that socio-cultural representations form resources from which women understand and talk about our bodies. The research draws on three different data sources: genital definitions in medical and English language dictionaries, genital slang terms collected through questionnaires, and talk-data from 16 group and four individual interviews with women and one group interview with men. The analytic chapters are divided into two parts. In Part One, I present my analysis of socio-cultural representations, first providing an overview of themes found across a range of socio-cultural representation, and then focusing on two particular texts: dictionary definitions and genital slang. I use content analytic techniques to explore the ideological assumptions in dictionary definitions of women's and, comparatively, men's genitals, and to identify the semantic categories in genital slang. In Part Two, I analyse women's talk about the vagina, exploring the intersections between the socio-cultural and women's accounts of their own experience. In particular, I focus on talk about vaginal size, and talk about gendered identity. In my conclusion, I discuss the importance of such research for challenging, and changing, the way the vagina is constructed, and for women's sexual and reproductive health.
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Ramírez, Pino Ana. "Copuchas de la vagina." Tesis, Universidad de Chile, 2017. http://repositorio.uchile.cl/handle/2250/153184.
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Memoria para optar al título de Diseñadora Gráfica<br>Copuchas de la vagina es un proyecto editorial independiente
de carácter experimental que consta de una colección de 3
fanzines, que promueven el autocuidado de la salud sexual
femenina por medio de métodos alternativos, contenidos
en los saberes populares y ancestrales.
El proyecto nace por medio de un levantamiento de
información, estudio de campo e investigación sobre
cómo se relaciona la mujer con su educación sexual,
dentro del contexto nacional. A partir de esto se define
el perfil de la usuaria para observar y testear los fanzines,
medio que más se acopla a ellas en cuanto a formato,
información, interés y adquisición. De esta forma el
fanzine preserva el contenido para que sea traspasado
de generación en generación, sin perder conocimientos
de salud alternativa que se han omitido en la educación
sexual femenina.
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Delmanto, Armando [UNESP]. "Efeito do raloxifeno no epitélio vaginal de mulheres na pós-menopausa." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/93099.
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delmanto_a_me_botfm_prot.pdf: 1594635 bytes, checksum: 59b8850497a3a71e0f5ae2ec36c4ccb0 (MD5)<br>Fundação para o Desenvolvimento Médico e Hospitalar (Famesp)<br>Analisar o efeito do raloxifeno sobre o epitélio vaginal de mulheres pós-menopausa. Métodos: Estudaram-se prospectivamente entre novembro de 2004 a fevereiro de 2006, 80 mulheres na pós-menopausa. Quarenta pacientes receberam 6Omg/dia de raloxifeno (GR) e 40 mulheres compuseram o grupo não tratado (grupo controle, GC), pareado por idade e tempo de menopausa. O grupo tratado foi composto por pacientes com osteoporose de coluna lombar e/ou colo do fêmur. Foram excluídos aquelas com sinais e/ou sintomas de infecção do trato genital inferior e usuárias de terapia hormonal (TH) até seis meses prévios ao estudo. Os esfregaços vaginais foram coletados em dois momentos: inicial (MO) e após seis meses de seguimento (Ml). Para avaliação do epitélio vaginal foi utilizado o valor de maturação, com a contagem de células superficias, intermediárias e parabasais. Os esfregaços foram analisados por único citopatologista, sem conhecimento dos dados das pacientes. Para análise estatística empregou- se o teste t de Student, teste Wilcoxon Mann-Witney e o teste Qui-Quadrado. Resultados: Na comparação estatística inicial os grupos foram homogêneos. Comparando os momentos inicial e final, não foram observadas diferenças estatisticamente sígnífícativas nos valores medianos de maturação do epitélio vaginal e na porcentagem de células superficiais, intermediárias e parabasais entre os grupos. Não foi constatada correlação linear significativa entre o valor de maturação e a idade, o tempo de menopausa, o uso ou não de TH prévia, tabagismo e o índice de massa corpórea, em ambos os grupos. Conclusão: O tratamento com raloxifeno por seis meses não alterou o valor de maturação do epitélio vaginal em mulheres na pós-menopausa.<br>To analyze the effect of raloxifene on the vaginal epithelium of postmenopausal women. Methods: Eighty postmenopausal women were studied prospectively between November of 2004 and February of 2006. Forty patients received 6omglday of raloxifene (GR), and 40 women comprised the non-treated group (control group, CG), paired by age and time of menopause. The treated group was composed of patients with osteoporosis of the lumbar column and / or femur. Those with signs and / or symptoms of infection of the inferior genital tract and users of hormonal therapies (HT) up to six months prior to the study were excluded. Vaginal smears were collected at two moments: initial (MO) and after six months of follow-up (Ml). To evaluate the vaginal epithelium, the maturation value was determined, along with counts of superficial, intermediate and parabasal cells. Smears were analyzed by only one cytopathologist, without knowledge of patient data. For statistical analysis Student's t test, Wilcoxon Mann Witney test and Chi-Squared test were employed. Results: In the initial statistical comparison the groups were homogeneous. Comparing the initial and final moments, no statistically significant differences were observed in median values of vaginal epithelial maturation or in percentage of superficial, intermediate and parabasal cells between the groups. There was no significant linear correlation between value of vaginal epithelial maturation and age, time of menopause, use or not of previous HT, smoking or body mass index, in both groups. Conclusion: Treatment with raloxifene for six months did not alter the maturation value of vaginal epithelium in postmenopausal women.
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Lee, Yick-Kwong Chris. "A follow-up study of "atypical cells" in gynecologic cytology : the impact of the Bethesda System 2001 /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B34865652.
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Delmanto, Armando. "Efeito do raloxifeno no epitélio vaginal de mulheres na pós-menopausa /." Botucatu : [s.n.], 2006. http://hdl.handle.net/11449/93099.
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Resumo: Analisar o efeito do raloxifeno sobre o epitélio vaginal de mulheres pós-menopausa. Métodos: Estudaram-se prospectivamente entre novembro de 2004 a fevereiro de 2006, 80 mulheres na pós-menopausa. Quarenta pacientes receberam 6Omg/dia de raloxifeno (GR) e 40 mulheres compuseram o grupo não tratado (grupo controle, GC), pareado por idade e tempo de menopausa. O grupo tratado foi composto por pacientes com osteoporose de coluna lombar e/ou colo do fêmur. Foram excluídos aquelas com sinais e/ou sintomas de infecção do trato genital inferior e usuárias de terapia hormonal (TH) até seis meses prévios ao estudo. Os esfregaços vaginais foram coletados em dois momentos: inicial (MO) e após seis meses de seguimento (Ml). Para avaliação do epitélio vaginal foi utilizado o valor de maturação, com a contagem de células superficias, intermediárias e parabasais. Os esfregaços foram analisados por único citopatologista, sem conhecimento dos dados das pacientes. Para análise estatística empregou- se o teste t de Student, teste Wilcoxon Mann-Witney e o teste Qui-Quadrado. Resultados: Na comparação estatística inicial os grupos foram homogêneos. Comparando os momentos inicial e final, não foram observadas diferenças estatisticamente sígnífícativas nos valores medianos de maturação do epitélio vaginal e na porcentagem de células superficiais, intermediárias e parabasais entre os grupos. Não foi constatada correlação linear significativa entre o valor de maturação e a idade, o tempo de menopausa, o uso ou não de TH prévia, tabagismo e o índice de massa corpórea, em ambos os grupos. Conclusão: O tratamento com raloxifeno por seis meses não alterou o valor de maturação do epitélio vaginal em mulheres na pós-menopausa.<br>Abstract: To analyze the effect of raloxifene on the vaginal epithelium of postmenopausal women. Methods: Eighty postmenopausal women were studied prospectively between November of 2004 and February of 2006. Forty patients received 6omglday of raloxifene (GR), and 40 women comprised the non-treated group (control group, CG), paired by age and time of menopause. The treated group was composed of patients with osteoporosis of the lumbar column and / or femur. Those with signs and / or symptoms of infection of the inferior genital tract and users of hormonal therapies (HT) up to six months prior to the study were excluded. Vaginal smears were collected at two moments: initial (MO) and after six months of follow-up (Ml). To evaluate the vaginal epithelium, the maturation value was determined, along with counts of superficial, intermediate and parabasal cells. Smears were analyzed by only one cytopathologist, without knowledge of patient data. For statistical analysis Student's t test, Wilcoxon Mann Witney test and Chi-Squared test were employed. Results: In the initial statistical comparison the groups were homogeneous. Comparing the initial and final moments, no statistically significant differences were observed in median values of vaginal epithelial maturation or in percentage of superficial, intermediate and parabasal cells between the groups. There was no significant linear correlation between value of vaginal epithelial maturation and age, time of menopause, use or not of previous HT, smoking or body mass index, in both groups. Conclusion: Treatment with raloxifene for six months did not alter the maturation value of vaginal epithelium in postmenopausal women.<br>Orientador: Jorge Nahás Neto<br>Coorientador: Eliana Aguiar Petri Nahás<br>Banca: Paulo Traiman<br>Banca: Lúcia Simões Costa-Paiva<br>Mestre
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Anderson, Aaron W. ""My Vagina" and other stories." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4821/.
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This thesis includes seven short stories and a critical afterword. The afterword places the stories in their literary historical context in regards to creative nonfiction. It goes on to discuss the craft of fictionalizing autobiographical stories. Each of the stories should stand alone, though they follow the narrator's life for a number of years. Harlin Anderson is the narrator of all the stories.
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Buchberger, Andrea. "Infektionen an Vulva, Vagina und Zervix." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-98380.
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Fernandes, Tatiane Rosa 1981. "Influencia do uso tópico do estrogênio ou testosterona ou acido poliacrilico sobre a funçao sexual em mulheres na pós menopausa = ensaio clinico controlado e aleatorizado = Eficcacy of vaginally applied estrogen, testosterone, polyacrylic acid on sexual function in postmenopausal women: a randomized controlled trail." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313671.
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Orientador: Aarão Mendes Pinto-Neto<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-23T11:12:13Z (GMT). No. of bitstreams: 1
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Previous issue date: 2013<br>Resumo: Introdução: A atrofia vaginal é uma condição crônica frequente em mulheres na pós-menopausa que acarreta alterações em sua sexualidade e consequentemente em sua qualidade de vida. Recentes estudos avaliam novas alternativas de tratamento para essa ascendente queixa da população feminina. Entretanto, atualmente dispomos de poucas opções terapêuticas adequadamente avaliadas. Objetivo: Comparar a função sexual feminina após o uso tópico de estrogênio, testosterona e ácido poliacrílico com o uso de lubrificante vaginal. Métodos: Ensaio clinico randomizado com 80 mulheres na pós-menopausa, entre 40 e 70 anos, em seguimento no Ambulatório de Menopausa do CAISM Unicamp. As mulheres foram randomizadas para o tratamento tópico via vaginal com estrogênio, testosterona, ácido poliacrílico e lubrificante, três vezes na semana, por um período de 12 semanas, entre novembro de 2011 a janeiro 2013. Utilizou-se o Índice de Função Sexual Feminina para avaliar as mudanças da resposta sexual no início e após 6 e 12 semanas. Resultados: O ácido poliacrílico e a testosterona tópica, em comparação com o lubrificante após 12 semanas de tratamento, apresentaram aumento nos domínios: desejo sexual, lubrificação, satisfação, dor na relação sexual e escore total. O tratamento com o estrogênio tópico em comparação com o lubrificante apresentou melhora no domínio desejo. A análise intragrupo ao longo do tempo de tratamento evidenciou melhora nos domínios desejo, lubrificação, dor para as mulheres que utilizaram ácido poliacrílico, testosterona e estrogênio. Além disso, as mulheres que utilizaram testosterona apresentaram melhora ao longo do tempo nos domínios excitação, orgasmo e satisfação. Conclusão: O tratamento por 12 semanas- em mulheres na pós-menopausa com sintomas de atrofia vaginal - realizado com ácido poliacrílico, testosterona e estrogênio demonstrou melhora na função sexual feminina. quando comparado ao uso de lubrificante vaginal<br>Abstract: Introduction. Female libido is multifactorial and complex. Declining estrogen levels in postmenopausal women affects vaginal function. Aim. To evaluate female sexual function after using topical estrogen, testosterone or polyacrylic acid as vaginal lubricants with K-Y jelly as a placebo lubricant. Methods. This was a randomized controlled clinical trial on 80 postmenopausal women between 40 and 70 years of age with follow-up at the Menopause Clinic of the CAISM / Unicamp. The women were randomized to treatment with topical vaginal estrogen, testosterone, polyacrylic acid or oil lubricant alone, three times a week for a period of 12 weeks from November 2011 to January 2013. Main Outcome Measures. We used the Female Sexual Function Index (FSFI) to assess changes in sexual response at baseline, and after 6 and 12 weeks. Results. After 12 weeks of treatment, polyacrylic acid and topical testosterone produced improvements in the FSFI domains of sexual desire, lubrication, satisfaction, reduced pain during intercourse and total score compared with lubricant alone. Treatment with topical estrogen in comparison with lubricant alone showed an improvement in the FSFI field of desire. The intragroup analysis over the time of the treatment showed improvements in the fields of desire, lubrication, and reduced pain for polyacrylic acid, testosterone and estrogen. Furthermore, women who used testosterone showed improvements over time in the fields of arousal, orgasm and satisfaction. Conclusions. Treatment of postmenopausal women with symptoms of vaginal atrophy with polyacrylic acid, testosterone and estrogen for 12 weeks produced improvements in self-reported female sexual function when compared with a lubricant<br>Mestrado<br>Fisiopatologia Ginecológica<br>Mestra em Ciências da Saúde
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Jakobsson, Tell. "Lactobacillus iners and the normal vaginal flora." Doctoral thesis, Linköping : Department of Clinical and Experimental Medicine, Linköping University, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11334.
Full textBooks on the topic "Vagina"
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J, Wilkinson Edward, ed. Pathology of the vulva and vagina. Churchill Livingstone, 1987.
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H, Kaufman Raymond, and Kaufman Raymond H, eds. Benign diseases of the vulva and vagina. 4th ed. Mosby, 1994.
Find full textBook chapters on the topic "Vagina"
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Houghton, Oisin, and W. Glenn McCluggage. "Vagina." In Histopathology Specimens. Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-673-3_26.
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Fahmy, Mohamed A. Baky. "Vagina." In Rare Congenital Genitourinary Anomalies. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43680-6_12.
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Houghton, Oisin P., and W. Glenn McCluggage. "Vagina." In Histopathology Specimens. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-57360-1_26.
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Heilmann, H. P., and H. Bünemann. "Vagina." In Strahlentherapie. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-79432-2_32.
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Riethdorf, L. "Vagina." In Spezielle pathologische Anatomie. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56781-0_5.
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Zaspel, Uta, and Bernd Hamm. "Vagina." In MRI and CT of the Female Pelvis. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-68212-7_12.
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Lierse, Werner. "Vagina." In Applied Anatomy of the Pelvis. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71368-2_21.
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Costa, S. D. "Vagina." In Die Gynäkologie. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-11496-4_22.
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Kaufmann, M. "Vagina." In Die Gynäkologie. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-11496-4_35.
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Riethdorf, Lutz, and Thomas Löning. "Vagina." In Pathologie. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-04564-6_17.
Full textConference papers on the topic "Vagina"
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Kaur, Inderjit. "Case report of vaginal melanoma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685370.
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Primary malignant melanoma of vagina is a rare disease with a predilection for local recurrence, distant metastasis and short survival time. Due to the low incidence and lack of reporting in the literature, treatment choices still remain controversial. We describe 2 cases of vaginal malignant melanoma. A 42 yr old female presented with complaints of post coital and per vaginal bleed of 1 month duration. Examination findings shows growth 6 cm x 6 cm on anterior vaginal wall, another 3 x 3 cm lesion on right lateral vagianl wall. Vaginal biopsy showed malignant melanoma, S-100 and HMB-45 positive while negative for CK and LCA. MRI Whole abdomen showed altered lesion [3.8 cm (AP), 6.0 cm (TR) and 4.9 cm (CC)] in upper 2/3rd of vagina extending into vaginal fornices and abutting right lower cervix superiorly, right paravaginal extension and mesorectal fascia. No significant enlarged lymph nodes were seen. In view of localised disease she underwent Type III Radical hysterectomy with bilateral salpingo-ophorectomy with bilateral pelvic lymphnode dissection with total vaginectomy. Histopathology s/o 2 tumour nodules, one located in the anterior vaginal cuff measuring – 5 x 5 x 3.2 cm, another located in right lateral vaginal cuff measuring 2.5 x 3 x 1.5 cm, malignant melanoma with involvement of the cervix with full thickness stromal invasion (2.8/2.8 cm,) invading perivaginal soft tissue, distance of invasive carcinoma from closest stromal margin <0.1 cm (12 O’ clock), LVI, PNI – not seen, all pelvic LN free (0/25). In view of positive margin and full thickness stromal involvement, she received radiotherapy to pelvis and Inguinal region to a dose of 45 Gy/25# followed by a boost of 16 Gy/8# to the tumour bed till 01/01/16. Another case is a 40 yrs female, presented with complaints of bloody discharge per vaginum of 4 months duration. On examination, there was a large growth occupying the vagina till introitus. Cervix normal, para free. MRI Pelvis showed altered lesion involving left lateral uterine cervix and upper 2/3rd of vagina with full thickness stromal involvement with mild left parametrial, anterior and posterior paravaginal extension, measuring 2.9 x 4.5 x 5.3 cm. Few subcmlymphnodes were seen in bilateral external and internal iliac regions (L>R). Vaginal Biopsy was suggestive of Malignant Melanoma, expressing S-100, HMB 45 and SDX-10. Metastatic work up was negative. She underwent RH with total vaginectomy with bilateral PLND with RPLND. HPR showed exophytic black growth seen involving all quadrants of vagina, extending upwards into both lips of cervix – 7 x 6 x 2.5 cm, Malignant melanoma, distance of invasive carcinoma from closest margin: <0.1 cm (paravaginal soft tissue), 3/8 right Pelvic LN, ECE +, 01/9 Left pelvic LN, ECE absent, 0/6 Right common iliac LN, 0/1 Reperitoneal LN was seen. She received adjuvant radiotherapy to a dose of 50 Gy/25# to the pelvis and inguinals→ boost of 6 Gy/3# to nodal regions showing ECE & 10Gy/5# to the primary region.
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Tokar, Stacy, Andrew Feola, Pamela A. Moalli, and Steven Abramowitch. "Characterizing the Biaxial Mechanical Properties of Vaginal Maternal Adaptations During Pregnancy." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19394.
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Pelvic organ prolapse impacts the lives of many women. Injury during vaginal delivery is considered to be one of the greatest risk factors for developing this disorder. In this study, we characterized vaginal adaptations during pregnancy in terms of changes in the mechanical behavior of virgin and mid-pregnant vaginas using a planar biaxial mechanical testing protocol to determine the change necessary to avoid maternal birth injury. The findings of this study show that the vagina is anisotropic and that the tissue becomes more distensible circumferentially by mid-pregnancy in the rodent model.
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Kaur, Inderjit, Swarupa Mitra, Manoj Kumar Sharma, et al. "Case report of vaginal melanoma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685371.
Full textAbstract:
Primary malignant melanoma of vagina is a rare disease with a predilection for local recurrence, distant metastasis and short survival time. Due to the low incidence and lack of reporting in the literature, treatment choices still remain controversial. We describe 2 cases of vaginal malignant melanoma. A 42 yr old female presented with complaints of post coital and per vaginal bleed of 1 month duration. Examination findings show growth 6 cm x 6 cm on anterior vaginal wall, another 3 x 3 cm lesion on right lateral vaginal wall. Vaginal biopsy showed malignant melanoma, S-100 and HMB-45 positive while negative for CK and LCA. MRI Whole abdomen showed altered lesion [3.8cm (AP), 6.0cm (TR) and 4.9cm (CC)] in upper 2/3rd of vagina extending into vaginal fornices and abutting right lower cervix superiorly, right paravaginal extension and mesorectal fascia. No significant enlarged lymph nodes were seen. In view of localised disease she underwent Type III Radical hysterectomy with bilateral salpingo-ophorectomy with bilateral pelvic lymphnode dissection with total vaginectomy. Histopathology s/o 2 tumour nodules, one located in the anterior vaginal cuff measuring – 5 x 5 x 3.2 cm, another located in right lateral vaginal cuff measuring 2.5 x 3 x 1.5 cm, malignant melanoma with involvement of the cervix with full thickness stromal invasion (2.8/2.8 cm,) invading perivaginal soft tissue, distance of invasive carcinoma from closest stromal margin <0.1cm (12 O’ clock), LVI, PNI – not seen, all pelvic LN free (0/25). In view of positive margin and full thickness stromal involvement, she received radiotherapy to pelvis and Inguinal region to a dose of 45 Gy/25# followed by a boost of 16 Gy/8# to the tumour bed till 01/01/16. Another case is a 40 yrs female, presented with complaints of bloody discharge per vaginum of 4 months duration. On examination, there was a large growth occupying the vagina till introitus. Cervix normal, para free. MRI Pelvis showed altered lesion involving left lateral uterine cervix and upper 2/3rd of vagina with full thickness stromal involvement with mild left parametrial, anterior and posterior paravaginal extension, measuring 2.9 x 4.5 x 5.3 cm. Few subcmlymphnodes were seen in bilateral external and internal iliac regions (L>R). Vaginal Biopsy was suggestive of Malignant Melanoma, expressing S-100, HMB 45 and SDX-10. Metastatic work up was negative. She underwent RH with total vaginectomy with bilateral PLND with RPLND. HPR showed exophytic black growth seen involving all quadrants of vagina, extending upwards into both lips of cervix – 7 x 6 x 2.5 cm, Malignant melanoma, distance of invasive carcinoma from closest margin: <0.1 cm (paravaginal soft tissue), 3/8 right Pelvic LN, ECE +, 01/9 Left pelvic LN, ECE absent, 0/6 Right common iliac LN, 0/1 Reperitoneal LN was seen. She received adjuvant radiotherapy to a dose of 50 Gy/25# to the pelvis and inguinals→ boost of 6 Gy/3# to nodal regions showing ECE & 10 Gy/5# to the primary region.
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Feola, Andrew J., Keisha Jones, Marianna Alperin, Robbie Duerr, Pam A. Moalli, and Steven Abramowitch. "Establishing an Animal Model for the Evaluation of Vaginal Meshes." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206762.
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Roughly three million women in the United States give birth vaginally each year [1]. Clinically, the vagina undergoes pronounced adaptations up to the time of delivery, presumably to afford passage of the fetus [2]. Our group has suggested that if these adaptations are not sufficient or if fetus size is too large, an injury to the vagina or its supportive tissues will likely result. Vaginal injury at the time of delivery occurs quite frequently and research examining the levator ani muscle, the major muscular component of the pelvic floor, revealed injury in up to 20% of women who have given birth vaginally [3]. Therefore, vaginal birth is considered one of the greatest risk factors for pelvic floor disorders (i.e. urinary dysfunction and pelvic organ prolapse) later in life.
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Bansal, Nupur, Abhishek Soni, Anil Khurana, Yashpal Verma, Paramjeet Kaur, and Ashok Kumar Chauhan. "Vaginal dilator therapy to prevent stenosis from radiotherapy: A systematic review." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685362.
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Background: Pelvic radiotherapy may damage the vagina and cause vaginal stenosis. Its incidence in the literature ranges from 1.2% to 88%. To prevent vaginal stenosis, routine vaginal dilation is recommended during and after pelvic radiotherapy. Materials and Methods: The objective was to examine critically the evidence behind this guideline. Searches included the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and Google scholarly articles. All the relevant articles were included in the study. Discussion: Various studies gave recommendations on dilation during or immediately after radiotherapy. Literature does not support routine vaginal dilatation during or immediately after pelvic radiotherapy. Occasional penetration might prevent the sides of the vagina adhering to each other, and dilation might be valuable once the inflammatory and psychological scarring has settled. Two trials demonstrated that encouraging vaginal dilation increased patient compliance, but no difference was found in sexual function scores in the first trial. One retrospective study reported that dilation lowered stenosis rates, but the control group is not comparable. One study involving 89 women revealed that the median vaginal length was 6 cm, six to ten weeks after radiation therapy, but women tolerated a 9-cm dilator/measurer after 4 months of dilation experience. One trial showed no significant advantage by inserting mitomycin C. A study of five women reported that vaginal stenosis can be treated by dilation even many years after radiotherapy. Dilation during or immediately after radiotherapy can cause damage, and there is no evidence that it prevents stenosis. Dilation might stretch the vagina if commenced after the inflammatory phase. Dilation has been associated with traumatic rectovaginal fistulae and psychological consequences. Conclusion: Vaginal dilation might help treat the late effects of radiotherapy, but it must not be assumed that this applies to the acute toxicity phase. Routine dilation during treatment is not supported by good evidence. Prophylactic and therapeutic dilation therapy needs to be considered separately and research is needed to determine when dilation therapy should start on a large population.
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Silva, Aline Custódio, Anna Gabriela Girardello Gomes, Mariana Madrona Ribeiro, Amanda Borges Barbero, Letícia Marques Neiverth, and Emilly Gabriela Castilho Garcia. "Síndrome de Mayer-Rokitansky-Kuster-Hauser: aspectospsicológicos." In 45º Congresso da SGORJ XXIV Trocando Ideias. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/jbg-0368-1416-20211311086.
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Introdução: A síndrome de Mayer-Rokitansky-Kuster-Hauser (MRKH) consiste na agenesia ou disgenesia da porção mulleriana da vagina e do útero, em que a mulher tem cariótipo feminino normal e funções ovarianas condizentes com a normalidade. Essa patologia causa extremo sofrimento psicológico, sendo necessário ajuda e orientação psicológica a fim de buscar satisfação e aumento da qualidade de vida da paciente. Objetivo: O presente trabalho visa mostrar o impacto do aspecto psicológico na vida das pacientes com síndrome de MRKH. Métodos: Este trabalho foi elaborado com base em uma criteriosa revisão da literatura, feita por meio pesquisa de artigos nas bases de dados Scientific Electronic Library Online (SciELO) e PubMed. As palavras-chave usadas foram “anormalidades congênitas”, “infertilidade” e “vagina”. Assim, foram selecionados 15 artigos, excluindo-se os relatos de caso. Resultados e conclusão: As mulheres com a síndrome de MRKH têm cariótipo 46 XX e fenótipo feminino, com função ovariana regular, caracteres secundários desenvolvidos, genitália externa nos padrões anatômicos e função endócrina normal. No quadro clínico, apresentam ausência de menarca com ou sem algia abdominopélvica cíclica, dispareunia ou incapacidade de ter relações sexuais por ausência ou encurtamento da vagina, além de infertilidade. No exame ginecológico, a vagina é hipoplásica ou até inexistente, exceto em casos de atividade sexual prévia, ausência de colo do útero, em fundo cego. Exames hormonais são normais. Ao ultrassom ou ressonância magnética, evidencia-se falta de útero. O tratamento de primeira linha é a dilatação vaginal, com aplicação de dilatadores vaginais que aumentam progressivamente o comprimento e o diâmetro da vagina ou técnicas para a criação de neovagina nos casos de agenesia vaginal. O destaque é o componente psicológico e o cuidado com ele. Instaura-se um quadro ansioso pelo conceito errôneo de que, para a realização do ato sexual e do prazer, o coito deve acontecer. Isso gera consequências negativas nas pacientes por acharem que não são “mulheres normais” e que não irão atingir a satisfação sexual, além de pensarem que terão de se casar com homens viúvos que já tenham descendentes, ou homens fisicamente deficientes que queiram adotar crianças. Ademais, a infertilidade causa medo de rejeição por parceiros, depressão e isolamento social. Assim, é imperiosa a presença de terapeutas que esclareçam a essas adolescentes que elas podem ter acesso à intimidade, aos relacionamentos e so prazer sexual, que construam a autoestima e estimulem a autoaceitação. Uma opção é a terapia em grupo, na qual mulheres diagnosticadas com síndrome de MRKH podem compartilhar experiências, sentimentos de dor, encontrando conforto e alívio, além de aconselhamento sobre adoção e reprodução assistida. Além disso, outra alternativa é o incentivo para que elas se apeguem à espiritualidade, uma vez que estudos relatam que a fé pode auxiliá-las a lidar com preocupações, ansiedades e a busca por explicações.
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Chamorro, Daniela Cardeño, Julio da Silva Almeida, Mario Fernando Davila Obando, et al. "Leiomioma vaginal: um relato de caso." In 47º Congresso da SGORJ e Trocando Ideias XXVI. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/jbg-2965-3711-2023133s116.
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Introdução: Os leiomiomas são neoplasias benignas compostas por células musculares lisas, que ocorrem comumente no trato genital feminino e podem apresentar-se como tumores únicos ou múltiplos. A causa desses tumores ainda é desconhecida, mas sabe-se que o seu crescimento é influenciado por fatores hormonais, especialmente estrogênicos. Por esse motivo, eles afetam principalmente mulheres em idade reprodutiva. Embora os leiomiomas uterinos sejam mais prevalentes, também há relatos de tumores da musculatura lisa em outros órgãos pélvicos, como a uretra, a vulva e a vagina, que podem apresentar características distintas. Os leiomiomas vaginais são tumores raros, com cerca de 300 casos relatados na literatura desde o primeiro caso documentado em 1733. Acredita-se que possam originar-se de células mioepiteliais (como as encontradas nas glândulas de Bartholin), células musculares lisas das vênulas, músculos vaginais ou miofibroblastos, mas a etiologia ainda não está claramente estabelecida. Relato de caso: Uma paciente de 23 anos, parda, procurou o ambulatório de ginecologia de outra unidade de saúde devido a uma lesão vaginal que surgiu há 3 meses. Há 20 dias, ela notou a presença de secreção purulenta proveniente da lesão após a prática de atividade física, mas negou qualquer episódio de dor local ou febre. Durante a consulta, a paciente apresentou um ultrassom transvaginal solicitado por outro profissional, que revelou uma lesão expansiva na parede lateral direita da vagina, medindo 3,8 × 2,0 × 4,1 cm. Uma ressonância magnética pélvica foi solicitada, a qual sugeriu uma possível origem uretral da lesão. Por isso, o ginecologista encaminhou a paciente ao urologista, que descartou a relação anatômica da lesão com a uretra e a encaminhou para o serviço de ginecologia da Santa Casa da Misericórdia do Rio de Janeiro. Durante a consulta, o exame físico revelou a presença de uma lesão sólida de aproximadamente 5 cm, com base entre o meato uretral e o introito vaginal, de textura elástica, móvel e com uma área ulcerada, aparentemente sem relação com as estruturas uretrais. Foi decidido realizar uma biópsia excisional no centro cirúrgico. Durante o procedimento cirúrgico, confirmou-se que a lesão não estava anatomicamente relacionada à uretra e procedeu-se à exérese do tumor. O resultado histopatológico confirmou um leiomioma vaginal degenerado, com dimensões de 6 × 5 × 3 cm. Comentários: As lesões expansivas na vagina são queixas pouco frequentes nos ambulatórios de ginecologia e apresentam uma ampla gama de diagnósticos diferenciais. A raridade de algumas doenças que afetam a região vaginal torna o diagnóstico desafiador e, consequentemente, pode levar ao atraso na resolução desses casos. Em casos de lesões miomatosas, a exérese é o método de escolha na maioria dos casos, levando sempre em consideração a viabilidade anatômica e o bom senso, respeitando as particularidades de cada situação. Relatos de casos como esse têm um grande valor como ferramentas para auxiliar na conduta de pacientes subsequentes afetadas por essas condições.
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Feola, Andrew, Masayuki Endo, and Jan Deprest. "Biomechanics of the Rat Vagina During Pregnancy and After Vaginal Delivery: A 3-Dimensional Ultrasound Approach." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14071.
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The vagina plays a focal point in support by directly supporting the bladder, urethra, uterus, and rectum. The vagina also is a central location for connective tissue and muscle attachments. Failure in any component of this intricate support system can lead to the development of pelvic floor disorders, such as pelvic organ prolapse (POP), urinary and fecal incontinence and sexual dysfunction.
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Feola, Andrew, Marianna Alperin, Pamela Moalli, and Steven Abramowitch. "Characterizing the Maternal Adaptations of Pregnancy and Recovery Following Vaginal Delivery in the Rodent Model." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19224.
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Pelvic organ prolapse and urinary incontinence are common conditions in women that significantly diminish quality of life. Vaginal delivery and maternal birth injury are the number one risk factors for the development of pelvic floor disorders. The goal of this study was to characterize maternal adaptations throughout pregnancy and recovery after vaginal delivery in terms of the passive quasi-static mechanical properties of the vagina using a rodent model. Virgin (n = 8), mid-pregnant (n = 7, day 15–16), late-pregnant (n = 7, day 20–21), immediate postpartum (n = 8, <2 hours post delivery), and 4 week postpartum (n = 6) Long-Evans female rats were utilized in this study. The mechanical properties (tangent modulus, tensile strength, ultimate strain, and strain energy density) were quantified by testing longitudinal sections of vaginal tissue to failure. The tangent modulus of virgin animals (25.1±5.1 MPa) was significantly higher compared to mid-pregnant (11.7±7.7 MPa, p = 0.003), late-pregnant (7.9±4.0 MPa, p<0.001), and immediate postpartum (8.5±4.7 MPa, p = 0.001) animals. A similar trend was also observed in the tensile strength, whereas the ultimate strain increased throughout pregnancy until the time of vaginal delivery. Recovery was observed four weeks postpartum as no significant difference was found from virgin animals for any of the parameters. This study has shown a significant decrease in the tangent modulus and tensile strength along with an increase in the ultimate strain of longitudinal sections of vaginal tissue throughout pregnancy. These maternal adaptations are likely to increase the overall distensibility of the vagina and allow for vagina delivery with minimal injury. This process appears to be effective in the rodent model as the properties recovered to virgin levels by 4 weeks. In the future, we hope to alter these adaptations or exceed them in order to study the risk and impact of birth injury in this model.
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Maciel, Chrystiane Helena, Mariana De Lima CarózioMariana De Lima Carózio, Pâmela Rodrigues Reina Moreira, Carlos Eduardo de Siqueira, and Juliane Teramachi Trevizan. "LEIOMIOMA VAGINAL EM FÊMEA CANINA – RELATO DE CASO." In I Congresso On-line Nacional de Clínica Veterinária de Pequenos Animais. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/2401.
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Introdução: O leiomioma trata-se de uma neoplasia benigna mesenquimal da musculatura lisa, caracterizada como uma massa globóide de base séssil ou de massa polipóide pedunculada intralumial. O principal local de desenvolvimento deste tumor é o canal vaginal em cadelas de meia idade. A contribuição do estrógeno para a formação do leiomioma ainda é controverso, haja visto que relatos em cadelas castradas têm sido reportados. Objetivo: Assim, objetiva-se com o presente estudo relatar um caso de leiomioma. Material e Métodos: uma cadela de 16 anos de idade, nulípara, sem raça definida com queixa principal de prolapso vaginal. Relato de Caso: O animal havia sido submetido à ovariohisterectomia eletiva há ± 2 anos atrás, devido histórico recorrente de prolapso vaginal (três vezes). No entanto, no exame físico foi possível constatar que não se tratava de um prolapso da mucosa vaginal ou de hiperplasia vaginal, mas sim de um nódulo penduculado (1,0 cm x 1,0 cm) aderido a porção dorsal da parede da vagina. A citologia do nódulo foi inconclusiva e a ressecção cirúrgica por meio da episotomia foi recomendada. Após a ressecção tumoral, o laudo histopatológico confirmou a suspeita de leiomioma vaginal. Os achados microscópicos revelaram área neoplásica de crescimento expansivo, não encapsulada com presença acentuada de leimiócitos irregulares. Conclusão: Em sua maioria, os tumores vaginais são benignos e o crescimento dessas projeções intralumiais ou extralumiais, podem acarretar compressão de vasos e órgãos abdominais, bem como obstrução do canal dificultando a cópula, sendo a recessão cirúrgica altamente recomendada A cadela obteve excelente recuperação após o procedimento cirúrgico sem demandar uso de quimioterápicos.
Reports on the topic "Vagina"
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Adar, Maia. Eau de Vagina: A Novel Investigation into Human Pheromones. ResearchHub Technologies, Inc., 2024. http://dx.doi.org/10.55277/researchhub.l928792f.
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Carrascal Triana, E. L., N. Herrera Pérez, and William Burgos Paz. Efecto del método de colecta seminal sobre la calidad espermática de carneros pre- y post- congelación/descongelación. Corporación colombiana de investigación agropecuaria - AGROSAVIA, 2019. http://dx.doi.org/10.21930/agrosavia.poster.2019.15.
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Diferentes métodos de colectas seminales han sido establecidos para extraer semen y analizar la calidad del eyaculado del macho reproductor, así como, criopreservar y posibilitar la multiplicación y difusión de genes a futuro. El presente trabajo tuvo como objetivo evaluar el efecto del método de colecta seminal (vagina arti cial-VA o electroeyaculación-EE) sobre la calidad espermática pre- y post- congelación/descongelación de carneros en el caribe húmedo colombiano.
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Chrispin, Thyeres Teixeira Bueno, Claudia Cristina Takano Novoa, and Marair Gracio Ferreira Sartori. Dilatadores vaginais produzidos por impressora 3d para uso em Ginecologia. Universidade Federal de São Paulo., 2022. http://dx.doi.org/10.34024/agits20220002.
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A agenesia vaginal é uma malformação congênita do trato reprodutivo das mulheres causada por uma anomalia na formação dos ductos paramesonéfricos (Müller), que são responsáveis por originar os órgãos genitais internos no sexo feminino. Os dilatadores vaginais têm como objetivo promover a dilatação e conscientização da musculatura do assoalho pélvico em mulheres com alguma disfunção nesta área por meio de tratamento de caráter progressivo. Particularmente entre mulheres com agenesia vaginal, a criação de dilatadores vaginais personalizados à sua própria anatomia, com auxílio de impressão 3D, pode ser uma excelente alternativa terapêutica.
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Charatsi, Dimitra, Polyxeni Vanakara, Michail Nikolaou, et al. Vaginal Dilator Use to Promote Sexual Wellbeing After Radiotherapy in Gynaecological Cancer Survivors: A Prospective Observational Study. Science Repository, 2021. http://dx.doi.org/10.31487/j.ijcst.2021.03.01.sup.
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Background: Since continuing advances in radiotherapy technology broaden the role of radiotherapy in the treatment of gynaecologic malignancies, the use of vaginal dilators has been introduced in order to mitigate the risk of vaginal stenosis. The main aims of this study were to investigate the vaginal dilator use efficacy in the treatment of radiation-induced vaginal stenosis and the vaginal dilator effect on sexual quality of life. Methods: We studied fifty-three patients with endometrial or cervical cancer. The participants were treated with radical or adjuvant external beam radiotherapy and/or brachytherapy. They were routinely examined at four time points post-radiotherapy when also they were asked to fill in a validated sexual function-vaginal changes questionnaire. A p-value less than 0.05 was considered statistically significant. Results: The vaginal stenosis grading score was decreased and the size of the vaginal dilator comfortably insertable was gradually increased throughout the year of vaginal dilator use while radiation-induced vaginal and sexual symptoms were improved throughout the year of VD use. All patients with initial grade 3 showed vaginal stenosis of grade 2 after 12 months of vaginal dilator use and 65.8% of the patients with grade 2 initial vaginal stenosis demonstrated final vaginal stenosis grade 1 while 77.8% of the participants with initial 1st size of vaginal dilators reached the 3rd vaginal dilator size after 12 months. Starting time of dilator therapy <= 3 months after the end of radiotherapy was associated with a significant decrease in vaginal stenosis. Additionally, there was an overall upward trend regarding patients’ satisfaction with their sexual life. Conclusion: Endometrial and cervical cancer survivors should be encouraged to use vaginal dilators for the treatment of vaginal stenosis and sexual rehabilitation after radiotherapy.
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Varello, John. Vaginal Cleansing before C-Section. Touch Surgery Publications, 2019. http://dx.doi.org/10.18556/touchsurgery/2016.s0165.
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Clavé, Henri. Minimally Invasive Vaginal Hysterectomy (MIVH). Touch Surgery Simulations, 2021. http://dx.doi.org/10.18556/touchsurgery/2021.s0179.
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Varello, John. Vaginal Cleansing before C-Section. Touch Surgery Simulations, 2019. http://dx.doi.org/10.18556/touchsurgery/2019.s0165.
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Pasic, Resad. Total Vaginal Hysterectomy with Bilateral Salpingectomy. Touch Surgery Simulations, 2017. http://dx.doi.org/10.18556/touchsurgery/2017.s0112.
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Pasic, Resad. Total Vaginal Hysterectomy with Bilateral Salpingectomy. Touch Surgery Simulations, 2017. http://dx.doi.org/10.18556/touchsurgery/2018.s0112.
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Danan, Elisheva R., Susan Diem, Catherine Sowerby, et al. Genitourinary Syndrome of Menopause: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2024. http://dx.doi.org/10.23970/ahrqepccer272.
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Objectives. To conduct a systematic review of evidence regarding genitourinary syndrome of menopause (GSM) screening, treatment, and surveillance. Data sources. Ovid/Medline®, Embase®, and EBSCOhost/CINAHL® from database inception through December 11, 2023. Review methods. We employed methods consistent with the Agency for Healthcare Research and Quality Evidence-based Practice Center Program Methods Guidance to identify studies and synthesize findings for Key Questions related to screening for GSM, effectiveness and harms of U.S.-available interventions for GSM, appropriate followup intervals for patients using GSM treatments, and endometrial surveillance for patients using hormonal GSM treatments. For vaginal estrogen and vaginal or systemic non-estrogen hormonal interventions, energy-based interventions, and vaginal moisturizers, we first assessed study quality and then, for moderate or high-quality studies, reviewed outcomes related to GSM symptoms, treatment satisfaction, and adverse effects. For low-quality studies, we described limited study characteristics only. For studies of other non-hormonal interventions, we created an evidence map describing study characteristics without assessing study quality. Results. After assessing 107 publications for risk of bias (RoB), we extracted and synthesized effectiveness and/or harms outcomes from 68 publications describing trials or prospective, controlled observational studies that were rated low, some concerns, or moderate RoB (24 estrogen publications, 35 non-estrogen, 11 energy-based, and 4 moisturizers). Of 39 high, serious, or critical RoB publications, we extracted long-term harms from only 15 uncontrolled studies of energy-based interventions (all serious or critical RoB due to confounding). An additional 66 publications evaluating 46 non-hormonal interventions, including natural products, mind/body practices, and educational interventions, were described in an evidence map. Across all 172 publications, studies differed in GSM definitions, diagnosis, enrollment criteria, and outcomes assessed. Few studies enrolled women with a history of breast or gynecologic cancers. Overall, we found that vaginal estrogen, vaginal dehydroepiandrosterone (DHEA), vaginal moisturizers, and oral ospemifene may all improve at least some GSM symptoms, while evidence does not demonstrate the efficacy of energy-based therapies, vaginal or systemic testosterone, vaginal oxytocin, or oral raloxifene or bazedoxifene for any GSM symptoms. Harms reporting was limited, in part, by studies not being sufficiently powered to evaluate infrequent but serious harms, though most studies did not report frequent serious harms. Common non-serious adverse effects varied by treatment and dose. No studies evaluated GSM screening or directly addressed appropriate followup intervals or the effectiveness and harms of endometrial surveillance among women with a uterus receiving hormonal therapy for GSM. The longest followup period for active endometrial surveillance in an included trial was 12 weeks (vaginal estrogen) or 1 year (non-estrogen hormonal interventions). Conclusions. This systematic review provides comprehensive, up-to-date information to guide patients, clinicians, and policymakers regarding GSM. Despite the breadth of included studies, findings were limited by several factors, including heterogeneity in intervention-comparator-outcome combinations. Future studies would be strengthened by a standard definition and uniform diagnostic criteria for GSM, a common set of validated outcome measures and reporting standards, and attention to clinically relevant populations and intervention comparisons. Lack of long-term data assessing efficacy, tolerability, and safety of GSM treatments leaves postmenopausal women and clinicians without evidence to guide treatment longer than 1 year.