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Journal articles on the topic 'Vaginal tumors'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Kabra, Shashi L., Renu Singh, and Richa Madaan. "An unusual case of lateral vaginal wall leiomyoma: case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 6 (2024): 1596–98. http://dx.doi.org/10.18203/2320-1770.ijrcog20241455.

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Twenty to thirty percent of women in the reproductive age group are affected with leiomyomas, the most frequent benign tumor of the uterus. Only 300 occurrences of vaginal leiomyomas have been documented, hence they are still a rare condition. Because of their low incidence and wide range of nonspecific clinical symptoms, tumors are assumed to originate from Mullerian smooth muscle cells in the sub-epithelium of the vagina. However, these cells can easily be misdiagnosed. Usually located in the anterior vaginal wall are vaginal leiomyomas. Here, we describe a case of left upper lateral vaginal

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2

Muralinath, E., Kumar A. Tanuz, Kumar S. Mumtesh, et al. "Exploring Pharmacological Interventions for Vaginal Cancer: A Comprehensive Overview." Journal of Applied Nursing Research and Education 2, no. 1 (2024): 24–28. https://doi.org/10.5281/zenodo.10776675.

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<em>Vaginally cancer is a rare malignancy that happens in the cells of the vagina and pharmacological interventions play a major role managing vaginal cancer. Cisplatin, a platinum _ based chemotherapy drug, is used in a wide manner regarding the treatment of different types of cancers along with vaginal cancer. Cisplatin performs by interfering with the DNA inside the cancer cells, stopping their capability to divide and grow. 5_ Fluorosis uracil (5_ Fu) is an anti-metabolite drug that disrupts the synthesis of DNA and RNA, stopping the growth of cancer cells. Trastuzumide (Herceptin) is a mo

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3

Morshed, AKM Amirul, Zohora Jameela Khan, Habiba Khatun, et al. "Vaginal yolk sac tumour in infant : A rare case report." Journal of Paediatric Surgeons of Bangladesh 8, no. 1 (2018): 36–37. http://dx.doi.org/10.3329/jpsb.v8i1.69636.

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Malignant germ cell tumors are rare tumors in children accounting for 2-3% of childhood malignancies, usually occurring in midline structures. Yolk sac tumor is one of the form of Germ cell tumor among them extra gonadal yolk sac tumor is rare entity. Vaginal yolk sac tumor usually occurs below 3 years. Its occurrence in vagina is very rare & typically presents with vaginal bleeding, vaginal mass or sometimes mechanical urinary retention. We report a 10 months old girl presented with vaginal bleeding and high Alpha fetoprotein and as diagnosed as yolk sac tumor. Journal of Paediatric

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4

Betova, Tatyana, Radoslav Trifonov, Savelina Popovska, et al. "Primary Vaginal Mucinous Adenocarcinoma of Intestinal Type—Clinical, Radiological and Morphological Aspects." Medicina 60, no. 4 (2024): 525. http://dx.doi.org/10.3390/medicina60040525.

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Background and Objectives: Neoplasms of the vagina are rare and account for 1–2% of all tumors of the female reproductive system. Primary neoplasms of the vagina are most often carcinomas originating from squamous or glandular epithelium. Of the primary glandular tumors, clear cell, endometrioid, and serous adenocarcinomas are the most common types, while mucinous and mesonephric types are very rare. Mucinous adenocarcinoma is histologically subclassified into endocervical and intestinal types. We add to the existing literature another case of an extremely rare gynecological neoplasm—primary v

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5

Anju, G., Meenakshi Rao, Garima Yadav, and Pratibha Singh. "Vaginal Cellular Angiofibroma: Report of a Rare Case with Literature Review." Journal of Mid-life Health 15, no. 3 (2024): 213–16. http://dx.doi.org/10.4103/jmh.jmh_186_23.

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ABSTRACT Cellular angiofibroma (CA) is a relatively recently described, rare, benign soft tissue tumor that predominantly occurs in the vulvoperineal region. It was first described in 1997 as a mesenchymal-origin tumor composed of connective (fibrous) tissue and blood vessels. We report a case of vaginal CA in a 40-year-old woman who presented with pressure symptoms, incidentally diagnosed with a vaginal mass and clinically suspected as vaginal myoma. This case was diagnosed based on histomorphology and immunohistochemistry and underwent surgical treatment. This tumor was a diagnostic dilemma

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6

Elliott, P., D. Green, A. Coates, et al. "The efficacy of postoperative vaginal irradiation in preventing vaginal recurrence in endometrial cancer." International Journal of Gynecologic Cancer 4, no. 2 (1994): 84–93. http://dx.doi.org/10.1046/j.1525-1438.1994.04020084.x.

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Between 1960 and 1985 hysterectomy was performed on 811 FIGO stage I and 116 stage II endometrial cancers which were divided into three groups: low-risk stage Ii (grade 1 and 2 lesions confined to the inner third of the myometrium; high-risk stage Iii (grade 3 and/or invading to the middle third of the myometrium or beyond); and FIGO stage II tumors (also high-risk). Hysterectomy was the only treatment in 492; in 145 the vaginal vault alone was radiated and in 290 the whole vagina, in each instance by an intracavity dose of 60Gy; in 34 of the latter high-risk tumors the pelvis received an addi

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7

Sarmiento-Piña, Maira, and Eduardo Reyna-Villasmil. "Rabdomiosarcoma pleomórfico vaginal." Revista de Obstetricia y Ginecología de Venezuela 84, no. 04 (2024): 503–8. https://doi.org/10.51288/00840419.

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Vaginal rhabdomyosarcoma is a malignant soft tissue neoplasm of mesenchymal origin, characterized by the proliferation of immature skeletal muscle cells. Predominantly in childhood, it manifests most frequently in the head and neck region, although the second most common location is genitourinary. The embryonal subtype is the most frequent histologically, with an exophytic growth pattern and a better prognosis. Clinical, imaging (ultrasound and magnetic resonance imaging) and histopathological findings, together with positive immunohistochemistry for muscle differentiation markers, determine t

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8

Tanaka, Yuji, Mayuko Nagasaka, Mariko Takahashi, and Masashi Kobayashi. "Rare Epithelioid Leiomyoma of the Vagina Exhibiting a Pelvic Mass." Case Reports in Obstetrics and Gynecology 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/2190135.

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Epithelioid leiomyoma of the vagina is extremely rare. Smooth muscle tumors of the vagina usually present with a submucosal growth pattern or a pedunculated growth pattern from the anterior vaginal wall into the vaginal cavity. Here we report a case of a 43-year-old woman with a solid epithelioid leiomyoma and a palpable mass in the pouch of Douglas. Transvaginal biopsy and angiography showed the epithelioid leiomyoma feeding from the vaginal artery behind the posterior vagina. An abdominal wide excision of the tumor with a partial vaginectomy was performed. Our use of ultrasound-guided needle

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9

Weissman, Andrea, David Jiménez, Brian Torres, Karen Cornell, and Shannon P. Holmes. "Canine Vaginal Leiomyoma Diagnosed by CT Vaginourethrography." Journal of the American Animal Hospital Association 49, no. 6 (2013): 394–97. http://dx.doi.org/10.5326/jaaha-ms-5922.

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A 13 yr old female spayed Labrador retriever presented for vulvar bleeding. Abdominal radiographs revealed a soft tissue mass in the ventral pelvic canal. A computed tomography (CT) exam and a CT vaginourethrogram localized the mass to the vagina, helped further characterize the mass, and aided in surgical planning. A total vaginectomy was performed and the histologic diagnosis was leiomyoma. Vaginal tumors make up 1.9–3% of all tumors. Seventy-three percent of vaginal tumors are benign, and 83% of those are leiomyomas. Leiomyomas often have a good long-term prognosis with surgical resection.

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10

Ahmad, Fauzi, Albiruni Haryo, Fajar Shodiq Permata, and Nurina Titisari. "VAGINAL FIBROSARCOMA IN GOLDEN RETRIEVER DOG: CASE REPORT." Jurnal Veteriner 22, no. 1 (2021): 141–49. http://dx.doi.org/10.19087/jveteriner.2021.22.1.141.

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A Golden Retriever bitch, 10 years old, came to the Animal Hospital of Brawijaya University, Malang, Indonesia, her conditions was discharge from the vagina, stink smell, polyuria, polydipsia and swelling in the vaginal area that begin to appear one month ago. Physical examination results found her weight 30 kg, scored three for body condition score (scale 1-5), body temperature at 38ºC, pale mucous membrane, and Capillart Reill Time > 2 seconds. Hard mass was palpable in the vaginal area. Based on the anamnesis, physical examination and clinical symptoms, the bitch appeared have some diffe

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11

Cross, Nathan M., A. Luana Stanescu, Erin R. Rudzinski, Douglas S. Hawkins, and Marguerite T. Parisi. "Vaginal Ewing Sarcoma: An Uncommon Clinical Entity in Pediatric Patients." Journal of Clinical Imaging Science 7 (April 25, 2017): 17. http://dx.doi.org/10.4103/jcis.jcis_96_16.

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Ewing sarcoma, including classical Ewing sarcoma of the bone and primitive neuroectodermal tumors arising in bone or extraosseous primary sites, is a highly aggressive childhood neoplasm. We present two cases of Ewing sarcoma arising from the vagina in young girls. Previously reported cases in literature focused on their pathologic rather than radiographic features. We describe the spectrum of multimodality imaging appearances of Ewing sarcoma at this unusual primary site. Awareness of vaginal Ewing tumors may facilitate prompt diagnosis and lead to a different surgical approach than the more

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Pampalakis, Georgios, Eleni Zingkou, and Georgia Sotiropoulou. "KLK5, a novel potential suppressor of vaginal carcinogenesis." Biological Chemistry 399, no. 9 (2018): 1107–11. http://dx.doi.org/10.1515/hsz-2017-0302.

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Abstract Vaginal cancer is rare and largely unexplored. We found here that kallikrein-related peptidase 5 (KLK5) is coordinately expressed along with other KLKs in all stratified epithelia, including vagina, pointing to potential role(s) in differentiation. Further, we propose that KLK5 could be implicated in vaginal cancer development based on the fact that Klk5−/− mice are prone to develop vaginal tumors when exposed to 7,12-dimethylbenz[a]anthracene. Nf-κb activation is markedly enhanced in Klk5−/−, leading to increased resistance to apoptosis of mutated vaginal cells. This explains the hig

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13

Dannecker, C., A. Hasenburg, C. Petersen, and H. Schmidberger. "Vaginal and vulvar tumors." Die Onkologie 30, no. 8 (2024): 644–47. http://dx.doi.org/10.1007/s00761-024-01552-9.

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14

V.V., Artyomenko, Nastradina N.M., Chikanchi V.O., and Iacoban S.R. "Vaginal microbiome and neoplasms of the female reproductive system: a marker or a factor of influence?" REPRODUCTIVE ENDOCRINOLOGY, no. 71 (March 15, 2024): 84–92. https://doi.org/10.18370/2309-4117.2024.71.84-92.

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The study of the human microbiome is one of the most pertinent areas of science and medicine today. The impact of changes in the microbiome is widely discussed in the context of new approaches to the diagnosis, treatment and prevention of many diseases. At the same time, approaches to the management of patients with precancerous and cancerous diseases are changing along with the discovery of new approaches to the management of this category of patients. Scientists all over the world are studying changes in the vaginal microbiome and its role in the female oncological pathology. This article co

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15

Assadi, Ayesha Amanath, Dipshikha Maiti, and Debasish Bandyopadhyay. "Vaginal Bleeding in an Infant due to Extragonadal Germ Cell Tumor: A Case Report with Review of Literature." Indian Pediatrics Case Reports 4, no. 4 (2024): 219–22. http://dx.doi.org/10.4103/ipcares.ipcares_32_24.

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Abstract Background: The occurrence of germ cell tumors (GCTs) in the vagina is uncommon in children, with yolk sac tumors being the most commonly identified histological subtype in young female infants. Clinical Description: A 7-month-old baby girl was presented with gradually progressive painless vaginal bleeding for 2 weeks. The infant was otherwise thriving well with no evidence of any local or systemic abnormality or constitutional symptoms. Management and Outcome: The child’s initial laboratory investigations were normal except for mild anemia. Further tests revealed elevated alpha-fetop

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16

WEPPLER, E. H., and E. M. GAERTNER. "Malignant extragastrointestinal stromal tumor presenting as a vaginal mass: report of an unusual case with literature review." International Journal of Gynecologic Cancer 15, no. 6 (2005): 1169–72. http://dx.doi.org/10.1136/ijgc-00009577-200511000-00031.

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The clinical and pathologic features of a malignant extragastrointestinal stromal tumor presenting as a vaginal mass are discussed. A 66-year-old female presented with copious vaginal bleeding and spontaneous passage of tumoral tissue per vagina. Histologic assessment showed a mitotically active spindle cell neoplasm. Immunohistochemical analysis demonstrated the neoplasm to be positive for CD117 (transmembrane tyrosine kinase) and CD34, consistent with a malignant extragastrointestinal stromal tumor. Subsequent clinical examination revealed an 8-cm posterior vaginal wall mass, with probable o

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17

Mishra, Vidhi. "Acute presentation of undiagnosed vaginal leiomyoma in pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 11 (2022): 3187. http://dx.doi.org/10.18203/2320-1770.ijrcog20222817.

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Vaginal leiomyomas are rare benign solid tumors of the vagina. There are approximately 300 case reports available in the literature and the para-urethral site is extremely uncommon. Here we report a case of 29 a year old primi-gravida who presented with complaints of sudden protrusion of mass arising from anterior vaginal wall at 16 weeks of pregnancy. On per-vaginum examination firm, mildly tender mass 6×4×5 cm was palpated arising from the lower one third of anterior vaginal wall and ending approximately 1 cm proximal to the external urethral meatus, occupying whole of the introitus and it w

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18

B., Preethi, Monu Singh, Sarita Singh, and Pallavi Singh. "Uterine leiomyosarcoma: an unusual presentation." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 8 (2020): 3493. http://dx.doi.org/10.18203/2320-1770.ijrcog20203349.

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Uterine leiomyosarcomas are rare aggressive tumors, with high recurrence rates, even when confined to the uterine corpus at the time of diagnosis. It arises from smooth muscle of uterus and is a rare tumor that accounts for 2-5% of all uterine malignancies. These tumors typically spread hematogenously. Patients present with vague symptoms similar to those of patients with leiomyomas. Most patients are diagnosed with leiomyosarcoma postoperatively. Although prognosis remains dismal, various ongoing studies are investigating the role of advanced imaging, multimodality treatment, prognostic nomog

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Pingkan, Trifonia, Fitri Juniarta, Hartono Tjahjadi, and Meliyana Lai. "Magnetic Resonance Findings in Adolescent Vaginal Rhabdomyosarcoma: A Rare Case Report." Indonesian Journal of Cancer 16, no. 1 (2022): 63. http://dx.doi.org/10.33371/ijoc.v16i1.842.

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Introduction: Rhabdomyosarcoma (RMS) is a rare soft tissue tumor, mainly affecting children, adolescents, and adults younger than 15 years, representing 3% to 4% of all childhood malignancies. Genitourinary is the second-most-common location of RMS with around 25% of cases. We describe a rare case of vaginal rhabdomyosarcoma in adolescents with huge polypoid tumors. Case Presentation: A 15-year-old female presented with vaginal bleeding for seven months. Her medical story was unremarkable. The clinical examination showed a polypoid mass prolapsed from the vagina, and the laboratory result was

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20

Upadhyay, Manisha, Meenakshi Chauhan, Sarika Gautam, and Tek Chand Yadav. "Rare case of vaginal leiomyoma in an adolescent girl: a diagnostic dilemma." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (2018): 1269. http://dx.doi.org/10.18203/2320-1770.ijrcog20180936.

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Vaginal leiomyoma are very uncommon primary tumors of vagina. They are extremely rare in adolescent age group. They can have variable clinical presentations and could be difficult to diagnose at times in adolescents. We report an extremely rare and novel case of primary vaginal leiomyoma with hyaline degeneration in an adolescent girl which was primarily misdiagnosed as hematocolpos or vaginal malignancy due to its clinical presentation. A 14-year-old girl presented with complains of difficulty in passing urine and irregular vaginal bleeding. On per rectal examination an ill-defined bulge was

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Murofushi, Keiko Nemoto, Nozomi Kitamura, Yasuo Yoshioka, et al. "A Clinical Evaluation of American Brachytherapy Society Consensus Guideline for Bulky Vaginal Mass in Gynecological Cancer." International Journal of Gynecologic Cancer 28, no. 7 (2018): 1438–45. http://dx.doi.org/10.1097/igc.0000000000001305.

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ObjectivesAmerican Brachytherapy Society (ABS)-recommended interstitial brachytherapy (IBT) should be considered for bulky vaginal tumor thicker than 5 mm. The aim of this study was to evaluate the ABS consensus guideline for patients with severe vaginal invasion based on our long-term follow-up results.Methods/MaterialsThe study included 7 patients with vaginal cancer and 14 patients with cervical cancer invading to the lower vagina. Based on prebrachytherapy magnetic resonance imaging findings, patients received intracavitary brachytherapy (ICT) for vaginal tumors 5 mm or less or IBT for vag

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Ceballos, Katherine M., Julie-Ann Francis, and John L. Mazurka. "Gastrointestinal Stromal Tumor Presenting as a Recurrent Vaginal Mass." Archives of Pathology & Laboratory Medicine 128, no. 12 (2004): 1442–44. http://dx.doi.org/10.5858/2004-128-1442-gstpaa.

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Abstract Gastrointestinal stromal tumors are CD117 (c-Kit)–positive mesenchymal neoplasms with histologic and ultrastructural features of the interstitial cell of Cajal. While tumors outside of the gastrointestinal tract have been described, to our knowledge the case we present is the first such case in the vagina. We describe a 75-year-old woman with a recurrent vaginal gastrointestinal stromal tumor without apparent rectal involvement. This tumor was characterized by short intersecting fascicles of spindled cells, focal necrosis, and 12 to 15 mitoses per 50 high-power fields. Immunohistochem

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23

Yuan, Zhen, Dongyan Cao, Jiaxin Yang, Shen Keng, and Huifang Huang. "Vaginal Yolk Sac Tumors: Our Experiences and Results." International Journal of Gynecologic Cancer 27, no. 7 (2017): 1489–93. http://dx.doi.org/10.1097/igc.0000000000001020.

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ObjectiveVaginal yolk sac tumors (YSTs) are rare malignant germ cell tumors largely affecting children younger than 3 years. Because of their low incidence, there is no consensus regarding diagnosis and treatment. In this article, we describe the presentation, diagnosis, treatment, and outcomes of 16 patients with vaginal YSTs diagnosed and managed at our center.MethodsDiagnoses of YST of the vagina were confirmed by 2 experienced pathologists. All patients were treated with bleomycin, etoposide, and cisplatin (PEB) combination chemotherapy alone. Complete remission (CR) was defined by a norma

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Tiwari, Kalpana, Farendra Bhardwaj, Shagun Gupta, Umang Juneja, Tushar Prabha, and Harsh Patel. "CASE REPORT: VAGINAL LEIOMYOMA." International Journal Of Advanced Research 10, no. 04 (2022): 199–203. http://dx.doi.org/10.21474/ijar01/14533.

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Leiomyoma are benign, monoclonal tumors of the smooth muscle cells of the myometrium and contain large aggregations of extracellular matrix composed of collagen, elastin, fibronectin, and proteoglycan. [1] They are the most common benign tumors in females and are most frequently seen in uterus. Vaginal leiomyomas are very rare and often confused with a variety of vaginal tumors. Since the first detected case back in 1733 by Denys de Leyden approximately 300 cases have been reported in the literature so far. [2] They may present with varied symptoms depending on site, size and vascularity inclu

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Hananeh, Wael M., Zuhair B. Ismail, and Mousa H. Daradka. "Tumors of the reproductive tract of sheep and goats: A review of the current literature and a report of vaginal fibroma in an Awassi ewe." Veterinary World 12, no. 6 (2019): 778–82. http://dx.doi.org/10.14202/vetworld.2019.778-782.

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Aim: This study aimed to provide a summary of all online available literature of published clinical and histopathological data regarding tumors affecting the reproductive tract of female sheep and goats. In addition, a detailed description of the clinical history, clinical findings, and gross and histopathological findings of one case of vaginal fibroma in an adult Awassi sheep is provided for the first time. Materials and Methods: Internet search engines such as PubMed, ResearchGate, Scopus, ScienceDirect, and Google Scholar were used to collect all published articles in refereed journals fro

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Zhang, Qin, Can Tian, Kun Wang, et al. "A case of a vaginal Brenner tumor without a gland mimicking a borderline tumor: unusual morphology and diagnostic pitfalls." Journal of International Medical Research 48, no. 8 (2020): 030006052094653. http://dx.doi.org/10.1177/0300060520946536.

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Brenner tumor is a rare neoplasm of the vagina. This tumor is diagnosed according to the criteria of ovarian tumors. We report here a 64-year-old postmenopausal woman with a 2.0-cm sessile vaginal polyp for 9 years. Microscopic examination showed unusual features of no gland appearing in the tumor, but the other two characteristic components of transitional islands and dense fibrous stroma were observed. The tumor was diagnosed as a vaginal Brenner tumor on the basis of the definition proposed by the World Health Organization classification of female reproductive organ tumors. In our case, par

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Halat, S. K., and K. Bach. "Primary S100 Negative Amelanotic Spindle Vaginal Melanoma." American Journal of Clinical Pathology 158, Supplement_1 (2022): S83. http://dx.doi.org/10.1093/ajcp/aqac126.173.

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Abstract Introduction/Objective Vaginal melanoma is a rare malignancy composed of cells showing melanocytic differentiation and represents less than 3% of malignant vaginal tumors. It occurs in older women, typically in the distal third of the vagina. Outcomes are poor and median survival is less than 2 years. Macroscopically, 90% of these lesions are pigmented, polypoid and ulcerated. Microscopically they demonstrate diffuse, nested, trabecular, and/or fascicular patterns and are comprised of epithelioid cells with or without a spindle cell component. They are typically pigmented and S100 pos

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Nikitina, Vera P., Tatiana A. Zykova, Elena A. Shevyakova, et al. "Vaginal biocenosis in patients with gynecological cancers." Journal of Clinical Oncology 39, no. 15_suppl (2021): e17574-e17574. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e17574.

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e17574 Background: The purpose of the study was to assess vaginal biocenosis in patients with gynecological cancers (GCs) and in non-cancer women. Methods: The study included 50 patients aged 52.3+2 years with histologically verified GCs (cervical cancer – 23, endometrial cancer – 27) – group 1, and 22 non-cancer women aged 42.4+2.3 – group 2. Vaginal swabs were taken prior to antitumor treatment. Real-time PCR was used to determine the total bacteria mass (TBM) and DNAs of 16 groups of microorganisms: Lactobacillus spp., Enterobacteriaceae, Streptococcus spp., Staphylococcus spp., Gardnerella

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De Vlam, M., S. Pil, A. Schlake, and H. De Rooster. "Latex-casting of vessels relevant during vaginectomy in bitches." Vlaams Diergeneeskundig Tijdschrift 89, no. 2 (2020): 81–90. http://dx.doi.org/10.21825/vdt.v89i2.16356.

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Vaginectomy is an infrequently performed invasive surgery to control vaginal disorders in bitches. Indications for vaginectomy include vaginal tumors (leiomyoma, fibroleiomyoma and leiomyosarcoma), polyps and vaginal prolapse. The surgical technique is a two-step procedure and consists of an extended laparotomy approach with caudal ovariohysterectomy followed by an episiotomy approach with removal and reconstruction of the vaginal wall. Although the surgery itself is invasive, the combined approach results in a favorable outcome with an apparently low risk of intra- and postoperative complicat

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Galuppi, Andrea, Anna Myriam Perrone, Mariangela La Macchia та ін. "Local α-Tocopherol for Acute and Short-Term Vaginal Toxicity Prevention in Patients Treated With Radiotherapy for Gynecologic Tumors". International Journal of Gynecologic Cancer 21, № 9 (2011): 1708–11. http://dx.doi.org/10.1097/igc.0b013e318223659d.

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IntroductionData in literature about the use of adjuvant treatment to reduce acute adverse effects of radiotherapy on the pelvis are scant, with the exception of a few reports on the topical use of estrogen, which promotes proliferation of epithelium.Materials and MethodsIn this prospective trial, α-tocopherol acetate was topically administered to patients affected by endometrial and cervical cancer and undergoing radiation treatment to avoid acute vaginal complications.ResultsVaginal application of α-tocopherol reduced vaginal toxicity and pain, although vaginal secretion was not significantl

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Saratlija, Žana, Ante Gotovac, Mario Duvnjak, and Boris Bačić. "Combination of peritoneal flap and buccal mucosa graft vaginoplasty after vaginectomy due to recurrent planocellular vaginal cancer." International Journal of Reconstructive Urology 2, no. 2 (2024): 236–38. http://dx.doi.org/10.4103/ijru.ijru_16_24.

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ABSTRACT Primary vaginal cancer is rare, and the optimal approach has not yet been determined. First-line treatment can be radiotherapy or surgery. Surgical treatment is often mutilating and it requires reconstructive surgery. There are many vaginal reconstructive techniques, but none of them showed unequivocal superiority. A 40-year-old woman with planocellular vaginal carcinoma grade I underwent surgical excision of tumor combined with adjuvant radiotherapy. A year after the provided therapy, she experienced a local relapse of vaginal carcinoma. A multidisciplinary team for gynecological tum

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Yordanov, Angel, Milen Karaivanov, Stoyan Kostov, Vanya Savova, and Vasilena Dimitrova. "Extraovarian Brenner Tumor in the Vagina: A Case Report and Review of Literature." Reports 8, no. 3 (2025): 103. https://doi.org/10.3390/reports8030103.

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Background and Clinical Significance: Brenner tumors are rare epithelial tumors that can occur in both males and females. They consist of ovarian transition cells surrounded by dense fibrous tissue and can be classified as benign, borderline, or malignant. While most commonly found in the ovary, extraovarian Brenner tumors (EOBTs) have been reported in the uterus, vagina, broad ligament, and omentum. Case Presentation: A 71-year-old postmenopausal woman presented with a polypous formation on the upper third of the posterior vaginal wall, which was found at a routine health check. Macroscopical

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Mulita, Francesk, Vasileios Leivaditis, Platon Dimopoulos, et al. "Correlation between gynecological tumors and atherosclerotic diseases." Archives of Medical Science – Atherosclerotic Diseases 8, no. 1 (2024): 118–22. http://dx.doi.org/10.5114/amsad/176655.

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Gynecological cancer is among the leading causes of cancer-related mortality worldwide, with malignancies of the ovary, uterus, fallopian tube, cervix, vagina, and vulva making up 10–18% of all cancers diagnosed in women globally. Gynecological cancer and atherosclerosis are two of the most frequent medical entities that afflict women worldwide; thus the possible correlations between them ought to be explored. Vulvar, cervical, vaginal, endometrial, and ovarian cancers have been found to have common points with atherosclerosis regarding their pathogenesis and predisposing factors. Obesity and

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Shevchenko, N. A., V. V. Varyasin, I. G. Tsidaeva, O. V. Polikarpova, and A. A. Ayazova. "Achromatic vaginal melanoma. A rare clinical report." Russian Journal of Woman and Child Health 6, no. 2 (2023): 145–48. http://dx.doi.org/10.32364/2618-8430-2023-6-2-145-148.

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Melanoma is "a queen of malignant tumors" and one of the most rare and aggressive types of cancer. At the same time, it is the most well- known malignant tumor. The word "melanoma" is derived from the Greek melas, melanos means “dark, black.” However, there is also an amelanotic type of melanoma. Melanoma is associated with skin disorders, but can also occur in multiple organs and tissues: the choroid and iris, urogenital tract (vulva, vagina, uterine cervix, penis), mucous membrane of the gastrointestinal tract, meninges, lungs, etc. This is related to the fact that all these organs have mela

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Aslan Çataklı, Cansu, Zeynep Günay Uçmak, İsmail Kırşan, Özge Erdoğan Bamaç, and Necati Öztürk. "A case of vaginal prolapse and torsion uteri complicated by leiomyoma in a pregnant Aksaray malaklı dog." Veteriner Hekimler Derneği Dergisi 96, no. 1 (2025): 68–75. https://doi.org/10.33188/vetheder.1475285.

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In this case report, a case of prolapsed vagina with torsio uteri in a pregnant Aksaray malaklısı breed dog, aged 7.5 months and weighing 38 kg, is described. A female dog was brought to our clinic with a complaint of a mass protruding from the vagina for one month. In the anamnesis, dog's first proestrus bleeding occurred at the age of six months, no vaginal pathology was observed during this period, and the patient owner did not observe the dog mating. During vaginal examination, necrotic areas were detected in the completely prolapsed vaginal tissue. Urinary bladder was catheterized, and it

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Alcaraz, Jennifer E. Reyes, Guadalupe Guerrero Reyes, Adrian Gutierrez Gonzalez, et al. "Lower urinary tract symptoms secondary to a vaginal leiomioma the female prostate: case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 2 (2024): 417–19. http://dx.doi.org/10.18203/2320-1770.ijrcog20240144.

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This is a case report of lower urinary tract symptoms secondary to a vaginal leiomioma “the female prostate”. A 45-year-old female patient with no significant personal history, sensation of a vaginal foreign body accompanied by lower urinary tract symptoms, on vaginal physical examination with a 7×7 cm deep tumor, increased consistency, not painful, without hemorrhage. Magnetic resonance imaging with hypointense T1 and T2 images, few linear hyperintense areas in T2, homogeneous postgadolinium enhancement 69×66×53 mm, solid tumor dependent on the vaginal vault. Tumor markers CA 19-9: 5.98 U/ml,

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Tarrab, Rand, Alaa Al Sabbagh, and Dema Adwan. "Vaginal leiomyoma misdiagnosed as a Bartholin abscess: A case report from Damascus, Syria." SAGE Open Medical Case Reports 10 (January 2022): 2050313X2211240. http://dx.doi.org/10.1177/2050313x221124072.

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Fibroids are benign neoplasms that are primarily found in the uterus. Fibroids can rarely be found in the vagina—most commonly arising from the anterior wall. Generally, the vagina is an unusual location for tumors. In this article, we present the case of a 30-year-old multigravid Syrian woman presenting to the emergency department with painful swelling of the left labia, mistakenly diagnosed as a Bartholin abscess. A surgical excision was recommended for the solid mass and the mass was sent for histopathological examination which confirmed the diagnosis of a vaginal leiomyoma.

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Watanabe, Noriko, Hajime Okita, Kentaro Matsuoka, et al. "Vaginal yolk sac (endodermal sinus) tumors in infancy presenting persistent vaginal bleeding." Journal of Obstetrics and Gynaecology Research 36, no. 1 (2010): 213–16. http://dx.doi.org/10.1111/j.1447-0756.2009.01083.x.

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Sathya, Suresh, and Kathleen Linn. "Regression of a Vaginal Leiomyoma After Ovariohysterectomy in a Dog: A Case Report." Journal of the American Animal Hospital Association 50, no. 6 (2014): 424–28. http://dx.doi.org/10.5326/jaaha-ms-6082.

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An 11 yr old female mixed-breed Siberian husky was presented with a history of sanguineous vaginal discharge, swelling of the perineal area, decreased appetite, and lethargy. A single, large vaginal leiomyoma and multiple mammary tumors were diagnosed. Mastectomy and ovariohysterectomy were performed. The vaginal leiomyoma regressed completely after ovariohysterectomy. This is the first reported case of spontaneous regression of a vaginal leiomyoma after ovariohysterectomy in a dog.

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Mr, B. T. Abbas, S. M. A. Hassan Mr, A. K. Saeed Mr, and D. M. Amin Mr. "Vulvar and vaginal tumors in Hawshar dogs." Iraqi Journal of Veterinary Sciences 32, no. 1 (2018): 67–72. http://dx.doi.org/10.33899/ijvs.2018.153800.

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Carney, David, Clarence E. Clark, Ayana Chase, Gabriela Oprea-Ilies, and Jacquelyn Turner. "Gastrointestinal Stromal Tumors Presenting as Vaginal Bleeding." American Surgeon 85, no. 9 (2019): 485–87. http://dx.doi.org/10.1177/000313481908500921.

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Tsuda, K., T. Murakami, H. Kurachi, et al. "MR imaging of non-squamous vaginal tumors." European Radiology 9, no. 6 (1999): 1214–18. http://dx.doi.org/10.1007/s003300050820.

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Schnürch, Hans-Georg, Sven Ackermann, Celine D. Alt-Radtke, et al. "Diagnosis, Therapy and Follow-up of Vaginal Cancer and Its Precursors. Guideline of the DGGG and the DKG (S2k-Level, AWMF Registry No. 032/042, October 2018)." Geburtshilfe und Frauenheilkunde 79, no. 10 (2019): 1060–78. http://dx.doi.org/10.1055/a-0919-4959.

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Abstract Purpose This is an official guideline, published and coordinated by the Gynecological Oncology Working Group (AGO) of the German Cancer Society (DKG) and the German Society for Gynecology and Obstetrics (DGGG). Vaginal cancers are rare tumors, which is why there is very little evidence on these tumors. Knowledge about the optimal clinical management is limited. This first German S2k guideline on vaginal cancer has aimed to compile the most current expert knowledge and offer new recommendations on the appropriate treatment as well as providing pointers about individually adapted therap

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Souza, Francilberto Dyego de, Fernanda dos Passos e. Silva Leite, Ana Ricarlanda Cajaseiras Liberato, Carolina Mayumi Haruta, and Artur Eduardo de Oliveira Rangel. "Urethral leiomyoma: combined vaginal and abdominal approach – a case report." Revista Brasileira de Saúde Materno Infantil 22, no. 2 (2022): 431–35. http://dx.doi.org/10.1590/1806-9304202200020013.

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Abstract Introduction: leiomyomas are benign mesenchymal tumors of smooth muscle origin that can develop in various locations. Urethral leiomyomas are rare, with approximately only 120 cases reported in the literature. These tumors often occur in the third and fourth decades of life but are rare in menopausal patients. In general, treatment involves surgery, only three recurrence reports in the literature. Description: a case report on a 56-year-old woman; the patient had type II diabetes mellitus and chronic high blood pressure, was overweight (body mass index, 27.1 kg/m2), and a smoker. Besi

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KOZAK, Oksana, Hanna FEDORENKO, Serhiy ROMANENKO, Serhiy ROMANENKO, and Oksana RODAK. "USE OF NEEDLES IN IRRADIATION OF GYNECOLOGICAL TUMORS." Medical physics – the current status, problems, the way of development. Innovation technologies, no. 1 (2024): 163–68. https://doi.org/10.17721/3041-1491/2024.11-20.

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Introduction. Methods of irradiation of cervical cancer and other localizations in gynecology are constantly being improved. This is especially true for brachytherapy. Methods. New applicators are being created, new types of normalization are being introduced, irradiation zones are identified, to which it is recommended to apply different doses of irradiation, recommendations for irradiation of critical organs are changing, and priorities are being set in the irradiation process. Results. If more modern applicators are unavailable, additional introduction of needles freehand solves the problem

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Dung, Tran Ngoc, and Nguyen Anh Quan. "Vaginal leiomyoma: A case report." Tạp chí Nghiên cứu Y học 190, no. 5E16 (2025): 271–76. https://doi.org/10.52852/tcncyh.v190i5e16.3000.

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Vaginal leiomyomas are rare, benign mesenchymal tumors. Since Denys de Leyden identified the first case in 1733, there have been only around 300 reported cases. This case of a surgically treated vaginal leiomyoma highlights the importance of considering this rare diagnosis in reproductive-age women. We provide a review of the relevant literature on diagnosis and management.

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Guessan, Bi Néné, N. Edith Ngalande, Fanfan Mutsche, et al. "A Rare Discovery of a Voluminous Cervical Myoma Prolapsed Out of the Introitus at Day 15 Post Spontaneous Vaginal Delivery." Scholars Journal of Medical Case Reports 12, no. 01 (2024): 47–50. http://dx.doi.org/10.36347/sjmcr.2024.v12i01.012.

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Leiomyomas of the uterus are the most common pelvic tumors, occurring in nearly 70% of 45-year-old women. This case report presents a multiparous woman who presented with an intracervical myoma that remained undiagnosed prenatally and during pregnancy (with no antenatal checkups). The vaginal delivery was uneventful. The patient presented on day 15 of post-partum with a large sub mucosa fibroid which prolapsed out of the introitus. A myomectomy was performed by twisting and rotation via the vagina, without complications.

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Nagase, S., Y. Mikami, T. Moriya, et al. "Vaginal tumors with histologic and immunocytochemical feature of gastrointestinal stromal tumor: two cases and review of the literature." International Journal of Gynecologic Cancer 17, no. 4 (2007): 928–33. http://dx.doi.org/10.1136/ijgc-00009577-200707000-00028.

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Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract (GI). Although positive immunohistochemistry for c-kit protein (CD117) and CD34 is critical in establishing diagnosis, the clinicopathologic features of CD117-positive mesenchymal tumors without obvious connection to the GI tract are not well documented. We describe the clinicopathologic features of two cases of extra-GIST. Case 1 was a 42-year-old woman who presented with a submucosal tumor located in the posterior vaginal wall. Case 2 was a 66-year-old woman who presented with a mass that

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Soukaina, Fekkoul, Rhazi Inas, Taheri Hafsa, Saadi Hanane, and Mimouni Ahmed. "Non-puerperal uterine inversion caused by a leiomyoma." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 12 (2022): 3399. http://dx.doi.org/10.18203/2320-1770.ijrcog20223140.

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Uterine inversion is characterized by the invagination of the fundus of the uterus through the vagina. It’s a rare postpartum complication leading to massive bleeding and it’s extremely rare in non-puerperal cases. Non-puerperal uterine inversion is caused by tumors exerting force on the fundus of the uterus, turning the uterus inside out. It is most frequently associated with benign tumors such as submucosal leiomyomas however, malignant tumors can also be associated. We reported the case of 43-year-old women, G1P1, who was admitted at the emergency department for a bleeding vaginal prolapsed

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Arega, Chuchu, Wubshet Girma, and Jose Manuel Sanchez Diaz. "Angiofibroma of the Vagina Presenting with Abnormal Vaginal Bleeding: A Case Report from Ethiopia and Review of the Literature." Case Reports in Obstetrics and Gynecology 2019 (June 2, 2019): 1–4. http://dx.doi.org/10.1155/2019/1486387.

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Background. Angiofibroma is an uncommon type of vascular benign tumor that is made up of blood vessels and fibrous (connective) tissue. First described in 1997, it usually occurs in middle aged females and is clinically often thought to represent a cyst. Unlike most of the other site specific vulvovaginal mesenchymal lesions, cellular angiofibroma has a marked predilection for the vulva with only occasional examples reported in the vagina. Case Detail. A 17-year adolescent nulligravid girl presented with a history of irregular vaginal bleeding of two-year duration and history of lower abdomina

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