Relevant bibliographies by topics / Valeriani

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Academic literature on the topic 'Valeriani'

Author: Grafiati
Published: 22 February 2023

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Journal articles on the topic "Valeriani"

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Nejeschleba, Tomáš. "Metaphysica Valeriani Magni." American Catholic Philosophical Quarterly 93, no. 2 (2019): 361–83. http://dx.doi.org/10.5840/acpq2019311176.

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Plushner, Susyn L. "Valerian: Valeriana officinalis." American Journal of Health-System Pharmacy 57, no. 4 (2000): 328–35. http://dx.doi.org/10.1093/ajhp/57.4.328.

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Martinho, Ana, Sara M. Silva, Tiago Rosado, et al. "Valeriana spp.: Biological Activities and New In vitro and In vivo Perspectives." Current Bioactive Compounds 16, no. 3 (2020): 210–42. http://dx.doi.org/10.2174/1573407214666181026111431.

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Background:Valerian extract is widely used in dietary supplements as well as in conventional, traditional and alternative medicines. It is one of the most used herbal plants for the treatment of several disorders, mainly related to the digestive and the nervous systems. Dozens of chemical constituents with pharmacological and therapeutic properties were identified in essential oils and/or other extracts of valerian’s roots, rhizomes and aerial parts. This review summarizes and updates the current knowledge about the pharmacological properties of valerian, highlighting the most recent clinical, in vitro and in vivo findings, and intends to identify and propose future directions for further research regarding the effective biological effects of Valeriana spp.Methods:This review analyzed the scientific literature published in PubMed, Science Direct and Web of Science.Results:Some reports are contradictory or inconclusive, probably due to the presence of chemically distinct chemotypes within a species of Valeriana or to different approaches adopted in different studies. Also, there are a number of studies showing that co-administration of herbal supplements and drugs may promote pharmacokinetic and pharmacodynamic herb-drug interactions.Conclusion:It is of utmost importance to clarify the state of the art related to Valeriana spp. therapeutic properties and their effects on metabolism.
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Morokhina, S. L., R. N. Alyautdin, D. A. Kaperko, E. V. Shubnikova, I. I. Snegireva, and Yu A. Smirnova. "Adverse Reactions of Drugs Containing Valeriana and Corvalol: Analysis of Spontaneous Reporting." Safety and Risk of Pharmacotherapy 6, no. 4 (2018): 162–73. http://dx.doi.org/10.30895/2312-7821-2018-6-4-162-173.

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Abstract. Valerianа officinalis rhizomes whis roots, monocomponent and complex herbal drugs based on Valerianа officinalis, and the drug Corvalol containing chemically synthesized α-bromizovalerianic acid ethyl ester (ethyl bromovalerianate) are OTC drugs and are widely used. At the same time, in the database of drug adverse effects «Pharmacovigilance» AIS Roszdravnadzor from 2009 to 2018, 147 spontaneous reports of adverse reactions were registered when taking Valeriana rhizomes whis roots and Corvalol. The aim of the study was the analisis of spontaneous reporting about adverse reactions when taking Valeriana rhizomes and roots and the multi-component drug Corvalol in the database «Pharmacovigilance» AIS Roszdravnadzor and assessment of their compliance with the information in the instructions for medical use. It was reactions from the nervous system (lethargy, drowsiness, weakness, apathy, headache, dizziness, depression of consciousness, stupor, neurotoxicity, toxic encephalopathy), from the gastrointestinal tract (nausea, bitterness in the mouth, burning of the mucous membrane, belching, heartburn, appetite disorders), cardiovascular system (tachycardia) and allergic reactions (skin itching, skin flushing, rash, maculo-papular rash, urticaria, dermatitis, cheilitis, aphthous stomatitis, angioedema) in the reports. The sedative and anxiolytic effects of the leading biologically active component of rhizomes with valerian roots, valerenic acid, are mediated through modulation of the function of type-γ-aminobutyric acid receptors A. Experimentally confirmed that the mechanism of action of valerenic acid is similar to benzodiazepine drugs, which cause of a number of reported adverse neurological reactions. However, the range of complaints from patients cited in the reports is significantly wider than in the instructions for the medical use of these drugs. There is a need for further monitoring of reports and analysis of already received data and the addition of prescribing information of Valeriana rhizomes whis roots and Corvalol for ensuring safety requirements.
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Joshi, Vaishali C., Andres Navarrete, and Ikhlas A. Khan. "Authentication of Valeriana procera Kunth and Comparative Account of Five Valeriana Species." Journal of AOAC INTERNATIONAL 88, no. 6 (2005): 1621–25. http://dx.doi.org/10.1093/jaoac/88.6.1621.

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Abstract Valeriana procera Kunth (Mexican Valerian) is a commercially important species, sometimes used as a substitute for Valeriana officinalis L., an important sedative in herbal medicine. A detailed macroscopic and microscopic account was provided for V. procera Kunth and a comparison was made between the wild and cultivated samples of V. procera Kunth. Macroand microscopic comparative analyses were performed to differentiate V. procera Kunth from V. officinalis L. and other commercially important Valerian species such as V. jatamansi Jones, Valeriana edulis Nutt, and V. sitchensis Bong.
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Antolin, Michael F., and John F. Addicott. "Habitat Selection and Colony Survival of Macrosiphum valeriani Clarke (Homoptera: Aphididae)." Annals of the Entomological Society of America 81, no. 2 (1988): 245–51. http://dx.doi.org/10.1093/aesa/81.2.245.

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Carnino, Cecilia. "Gli anni rivoluzionari di Giuseppe Valeriani, un «patriota disinteressato, ingenuo e deciso» (1796-­1799)." SOCIETÀ E STORIA, no. 170 (November 2020): 707–34. http://dx.doi.org/10.3280/ss2020-170002.

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Odyntsova, V. M., V. H. Korniievska, S. V. Panchenko, Yu I. Korniievskyi, and V. I. Kokitko. "Chromato-mass spectrometric study of valerian infusion with various extractants." Current issues in pharmacy and medicine: science and practice 15, no. 1 (2022): 31–39. http://dx.doi.org/10.14739/2409-2932.2022.1.252374.

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Valerian Officinalis (Valeriana officinalis L.s.p.) is a collective species in Ukraine. It contains 13 species, including in the south of Ukraine grows valerian (V. stolonifera Czern.). At the present stage, it is confirmed that the calming and antispasmodic properties of valerian raw materials are due to the content of valepotriates, sesquiterpenoids and aromatic substances, in particular eugenol derivatives. That is why in many countries around the world a number of drugs have been created on their basis. The aim of our research is to determine the component composition of tinctures of tinctures of V. stolonifera Czern. made of 70 % alcohol and methanol using gas chromatography. Materials and methods. Raw materials (underground organs) Valerianae radices were harvested in March 2020 in Zaporizhzhia, Kantserivska Balka. Valerian tincture was prepared from fresh raw materials according to the method of making tinctures. The tincture was investigated on a gas chromatograph Agilent 7890B with mass spectrometric detector 5977B. The NIST14 mass spectrum library was used to identify the components. Results. 77 components were identified by gas chromatography in methanolic tincture of V. stolonifera Czern. roots, 13 components were isolated quantitatively. In the analysis of the chromatogram and the characteristic of the area of the peaks of the alcoholic tincture of V. stolonifera Czern. roots, 78 components were identified, 11 components were isolated quantitatively. At the comparative characteristic of chromatograms 39 components coincide. Of the main components, the largest content is: 13.413 RT methanolic 1(2H)-Naphthalenone, octahydro-4a,8a-dimethyl-7-(1-methylethyl)-, [4aR-(4a.α.,7.β.,8a.α.)] – 5.34 % 13.414 RT alcohol – 8.41 %; 11.943 RT methanolic Myrtenyl isovalerate – 3.88 %; 11,942 RT alcohol – 5.15 %; 15.362 RT methanolic Kessanyl acetate – 2.52 %; 15.360 RT Kessanyl acetate alcohol – 1.41 %. Conclusions. It was seen that valerian tinctures with methanol and alcohol extractant differ in both quantitative and qualitative composition analyzing the obtained data of gas chromatography. 39 Compounds were present in all tinctures; three of them were present in large quantities. According to the results of the study, data have been obtained that show that the best indicators of the quantitative and qualitative composition of the tincture of V. stolonifera Czern. were obtained using the extractant 70 % alcohol.
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Navarrete, Andres, Bharathi Avula, Young-Whan Choi, and Ikhlas A. Khan. "Chemical Fingerprinting of Valeriana Species: Simultaneous Determination of Valerenic Acids, Flavonoids, and Phenylpropanoids Using Liquid Chromatography with Ultraviolet Detection." Journal of AOAC INTERNATIONAL 89, no. 1 (2006): 8–15. http://dx.doi.org/10.1093/jaoac/89.1.8.

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Abstract The roots and rhizomes of various valeriana species are currently used as a sleeping aid or mild sedative. A liquid chromatography method has been developed that permits the analysis of chlorogenic acid, lignans, flavonoids, valerenic acids, and valpotrates in various valerian samples. The best results were obtained with a Phenomenex Luna C18(2) column using gradient elution with a mobile phase consisting of water and 0.05% phosphoric acid and 2100% acetonitrilemethanol (1 + 1) with 0.05% phosphoric acid. The flow rate was 0.8 mL/min and ultraviolet detection was at 207, 225, 254, 280, and 325 nm. Different valerian species and commercial products showed remarkable quantitative variations. Chlorogenic acid (0.21.2%), 3 lignans, linarin (0.0020.24%), and valepotriates were detected in all the valeriana species analyzed. Highest amounts of valerenic acids were detected in V. officinalis L., trace amounts in V. sitchensis, and none in the other species analyzed.
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Krystal, Andrew D., and Ilana Ressler. "The Use of Valerian in Neuropsychiatry." CNS Spectrums 6, no. 10 (2001): 841–47. http://dx.doi.org/10.1017/s1092852900001668.

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ABSTRACTValerian is a medicinal agent deriving from the plant Valeriana officinalis L. We reviewed the available literature on the use of valerian preparations in the treatment of neuropsychiatric disorders. Preclinical studies suggest that valerian has sedative and muscle-relaxant effects. Few clinical trials with valerian have been carried out in conditions other than insomnia. The insomnia studies have methodologic shortcomings but suggest that some preparations lead to significant subjective improvement in sleep complaints with remarkably few side effects. Furthermore, some evidence indicates that valerian preparations may have a mechanism of action and clinical characteristics that differ from the benzodiazepine-related sedative/hypnotics, making them more suitable for long-term use. If this safety profile and the plant's sedative/hypnotic efficacy are confirmed in double-blind, placebo-controlled trials with carefully and consistently prepared valerian compounds, then those compounds would fill an important and presently unfilled niche in the treatment of insomnia.
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Dissertations / Theses on the topic "Valeriani"

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URBAN, JEAN-DENIS. "Etudes chimiques et pharmacologiques preliminaires de nouvelles formes galeniques de valeriane, valeriana officinalis (l) d. C." Strasbourg 1, 1987. http://www.theses.fr/1987STR10672.

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Maurmann, Natasha. "Valeriana glechomifolia : crescimento e produção de valepotriatos em diferentes meios nutritivos e avaliação preliminar de atividade neurofarmacológica." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2006. http://hdl.handle.net/10183/24076.

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Valeriana glechomifolia é uma espécie vegetal endêmica da região sul do Brasil. Ela acumula valepotriatos em todos os seus órgãos, que são os possíveis componentes sedativos das espécies de Valeriana utilizadas farmaceuticamente. Foi comparado o crescimento in vitro de V. glechomifolia em meios de cultura sólidos Murashige e Skoog completo (MS), com 75% dos nutrientes inorgânicos (MS 75) ou em uma formulação modificada (M ) em culturas mantidas a longo prazo, por até 9 meses sem subcultura. Alterações da biomassa, do desenvolvimento de raízes e partes aéreas, bem como a produção dos valepotriatos acevaltrato, valtrato e diidrovaltrato foram avaliadas mensalmente. O maior aumento de biomassa e desenvolvimento foliar foi detectado em plantas cultivadas em meio MS, e o melhor desenvolvimento radicular foi observado em plantas cultivadas em meio MS modificado (M ) durante o cultivo. A análise por Cromatografia Líquida de Alta Eficiência mostrou que o máximo de rendimento de valtrato e diidrovaltrato foi após os seis meses de cultivo em plantas em meio M , enquanto a maior concentração de acevaltrato foi encontrada em plântulas cultivadas em meio MS 75, após sete meses de cultivo. Os resultados sugerem uma relação direta entre crescimento e acúmulo de valepotriatos, e um efeito positivo do aumento da quantidade de micronutrientes e de mesoinositol nos rendimentos valepotriatos em plantas mantidas em longo período de cultivo. Também foi analisado o efeito neurocomportamental de um extrato contendo uma mistura de valepotriatos (EV) de V. glechomifolia. Camundongos adultos foram tratados com doses de 1, 3 e 10 mg/kg de EV ou veículo, 30 minutos antes dos testes. Durante a exploração no campo aberto, os camundongos tratados com 10 mg/kg mostraram redução na locomoção e no comportamento exploratório (número de rearings) em comparação aos animais controle, e o EV não induziu alteração na ansiedade. Todos os grupos realizaram normalmente a tarefa de memória de reconhecimento de novo objeto, exceto o grupo que recebeu 3 mg/kg, que apresentou piora na memória de reconhecimento do novo objeto. Os resultados indicaram que os camundongos tratados com valepotriatos não apresentaram déficits de memória aversiva de longa duração, e apenas a dose de 3 mg/kg apresentou um prejuízo na tarefa de memória de reconhecimento de novo objeto, além de uma possível propriedade sedativa na dose de 10 mg/kg.<br>Valeriana glechomifolia is a plant species endemic to southern Brazil. It accumulates the terpene derivatives valepotriates, the presumed sedative components of the pharmaceutically used species of Valeriana, in all of its organs. In vitro growth of V. glechomifolia on solid Murashige and Skoog (MS) without phytohormones at full, 75% (MS 75) or on a modified formulation (M ) was compared in long term stock cultures kept for up to 9 months without subculture. Changes in biomass accumulation, development of roots and shoots, as well as the production of valepotriates acevaltrate, valtrate and didrovaltrate were monthly evaluated. The best root development was observed in plants grown on modified MS medium (M ∆ ), whereas highest biomass accumulation and leaf development were detected in MS medium grown plants throughout the period. High Performance Liquid Chromatography analysis showed maximal valtrate and didrovaltrate yields on M ∆ grown plants harvested after six months of culture, whereas acevaltrate concentration was highest on MS 75 grown plants after seven months of culture. The overall results suggest a direct relationship between growth and valepotriate accumulation, and a positive effect of increases in micronutrient and myo-inositol amounts on valepotriate yields of long-term stock-cultures. An extract containing a mixture of valepotriates (EV) of V. glechomifolia was evaluated in relation to neurobehavioral parameters. Adult mice were treated with doses of 1, 3 and 10 mg/kg of EV or vehicle, 30 minutes before tests. During exploration of an open field, mice treated with 10 mg/kg showed reduced locomotion and reduced exploratory behavior (number of rearings) compared to control animals, and the EV did not induce alterations in anxiety. All groups performed normally the task of novel object recognition memory, except the group receiving 3 mg/kg dose, which showed decrease in novel object recognition memory. The results indicated that mice treated with valepotriates presented no deficits in long-term memory for aversive training and presented an impairment in novel object recognition memory task only at 3 mg/kg, as well as a possible sedative proprieties at 10 mg/kg.
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De, Marchi Roberta <1993&gt. "VALERIANUS APUD PARTHOS IGNOBILI SERVITUTE CONSENUIT. La sorte dell’imperatore Valeriano: tradizioni divergenti a confronto." Master's Degree Thesis, Università Ca' Foscari Venezia, 2018. http://hdl.handle.net/10579/12676.

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La ricerca si apre con lo studio della battaglia di Edessa (260 d.C.), considerata nei suoi sviluppi evenemenziali come momento cruciale della storia romana: per la prima volta un imperatore romano, dopo essere stato vinto, viene condotto prigioniero dai nemici in terra straniera. Si esamina la cattura di Valeriano (253-260 d.C.) da parte di Shapur, re dei Persiani, collazionando le tradizioni divergenti (fonti epigrafiche, iconografiche e letterarie sia orientali che occidentali) con l’intento di chiarire il trattamento dell’imperatore in Persia fino alla sua morte. Inoltre, si analizza il comportamento del figlio Gallieno all’indomani della cattura del padre e il ruolo di Odenato nell’ultio Caesaris, così come emergono dai passi degli autori antichi. Infine, si tenta di ricostruire l’immagine di Valeriano mettendo a confronto fonti pagane e cristiane. Si sottolinea in tal senso come i due editti emanati dall’imperatore nel 257 e nel 258 d.C. abbiano influenzato gli autori antichi nel giudizio sull’operato del princeps, determinando il loro schieramento in due gruppi: l’uno favorevole e incline a consegnare ai moderni l’immagine di un “eroe nazionale” e l’altro ostile nei suoi confronti, poiché spiega la sua cattura alla luce di un piano punitivo di Dio.
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Rey, F., and de Abram Ana Pastor. "Valepotreatos de valeriana interrupta." Revista de Química, 2013. http://repositorio.pucp.edu.pe/index/handle/123456789/100495.

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Raíces de V. Interrupta contienen 12% de valepotreatos, fueron aislados Valtrato y dos nuevos compuestos11-Etoxiviburtinal, 11-Metoxiviburtinal. La estructura química fue caracterizada a partir de los datos RNM y EM.
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Campos, Mara Lúcia de. "Desenvolvimento físico e neurocomportamental de filhotes após exposição materna à valeriana (Valeriana officinalis) durante a gestação em ratas (Rattus Norvegicus Berkenhout,1769)." Universidade Federal de Juiz de Fora, 2012. https://repositorio.ufjf.br/jspui/handle/ufjf/1874.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-06-22T11:31:21Z No. of bitstreams: 1 maraluciadecampos.pdf: 1264653 bytes, checksum: b2a9f890fc102cc866b811fc0c301aae (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-07-13T15:28:50Z (GMT) No. of bitstreams: 1 maraluciadecampos.pdf: 1264653 bytes, checksum: b2a9f890fc102cc866b811fc0c301aae (MD5)<br>Made available in DSpace on 2016-07-13T15:28:50Z (GMT). No. of bitstreams: 1 maraluciadecampos.pdf: 1264653 bytes, checksum: b2a9f890fc102cc866b811fc0c301aae (MD5) Previous issue date: 2012-12-10<br>A valeriana é moderadamente sedativa e usada no tratamento da ansiedade e distúrbios do sono. De acordo com a literatura a exposição a psicofármacos que atuam em receptores GABA-A durante a gestação podem provocar alterações comportamentais nos filhotes na vida adulta. O objetivo do presente trabalho foi avaliar o efeito que a administração do extrato de Valeriana durante a gestação possa ter sobre o desenvolvimento físico, o desenvolvimento reflexológico, a ansiedade e a memória dos filhotes. As ratas prenhes foram distribuídas aleatoriamente em quatro grupos (n=10): controle (1ml de água destilada) e três grupos tratados com valeriana, via intragástrica, T-500 (500mg/Kg/dia), T-1000 (1000mg/Kg/dia) e T-2000 (2000mg/Kg/dia) do 12° ao 19° dia de gestação. Depois do nascimento, o comportamento materno foi registrado e os filhotes fêmeas e machos foram avaliados separadamente quanto a alterações no desenvolvimento físico e reflexológico. Os filhotes machos também foram avaliados na vida adulta, 90 dias, quanto à ansiedade e à memória. Os animais apresentaram algumas alterações nas datas de aparecimento dos sinais indicadores físicos, os quais não permaneceram na vida adulta. A data de aparecimento dos reflexos foi semelhante entre os grupos. Em relação à ansiedade e à memória na vida adulta, não houve diferença estatística entre os grupos nos testes utilizados. Portanto, não houve alteração no desenvolvimento neonatal e neurocomportamental dos ratos, não tendo sido possível verificar se tal fato se deveu aos componentes da Valeriana não passarem pela placenta ou se o extrato ser inócuo para os fetos.<br>Valerian is moderately sedative and used for anxiety problems and sleep disturbance. Previous studies have shown that the exposure to psychopharmacs acting on GABA-A system during gestation in rats can produce behavioral alterations in their descendants in the adult life. This work was designed to evaluate the effects of the exposure to Valeriana officinalis L. (Valerianaceae) during gestation on the physical and reflexological development of the offspring and on their anxiety state and memory in the adult stage. Pregnant rats were randomly distributed into four groups (n = 10): control (1 ml distilled water) and three valerian-treated groups with the doses T-500 (500 mg/Kg/ day), T-1000 (1000 mg/Kg/day) and T-2000 (2000 mg/Kg/ day), administered by gavage, from the 12th to 19th day of gestation. After birth, maternal behavior was evaluated and the physical and reflexological development of the offspring male and females was assessed separately. The anxiety and memory of offspring male were evaluated at 90 days of age. Maternal behavior was not affected by treatment with valerian. The offspring exhibited some alterations on the day of appearance of physical signs, which did not affect the adult life, whereas similar days of appearance of the reflexes were observed among the groups. No significant difference was detected in the offspring in the anxiety and memory tests. Therefore, no alterations in the neonatal and neurobehavioral development of rats exposed to valerian during intrauterine life were found in the present work.
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Hattesohl, Miguel Marc Bernhard. "Pharmakologische Untersuchungen zu Valeriana officinalis L.s.I. /." [S.l. : s.n.], 2006. http://www.gbv.de/dms/bs/toc/523285779.pdf.

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Silva, Andreia Loviane. "Análise química de espécies de valeriana brasileiras." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/18403.

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A importância dos estudos sobre as espécies de Valeriana brasileiras tem sido estimulada para se obter quantidades viáveis de compostos fitoterápicos que possam ser economicamente explorados. Neste trabalho procedeu-se ao estudo da composição química de dos óleos voláteis obtidos por aparelho modificado de Clevenger de sete espécies de Valeriana (V. chamaedryfolia, V. eichleriana, V. eupatoria, V. glechomifolia, V. salicariifolia, V. scandens e V. tajuvensis.) usando-se a Cromatografia Gasosa (com detectores de ionização por chama e espectrometria de massas) aliada ao uso de padrões e dos Índices de Retenção de Kovatz. Foram identificados 243 compostos. Três espécies de Valeriana tiveram mais de 92 % dos compostos identificados e duas outras espécies, 86 %. Os resultados foram comparados com os dados apresentados para V. officinalis L. Foi estabelecida a separação em dois grupos pela correlação do conjunto de variáveis multivariadas e a análise de componentes principais (PCA) selecionou os compostos que contribuíram significativamente para o agrupamento ou dispersão de espécies Valeriana. Também foram realizadas extrações com fluido supercrítico (SFE) para a espécie V. tajuvensis, usando dois solventes extratores (CO2 e propano). O rendimento percentual obtido na SFE foi superior ao do hidrodestilado (cleavenger). Houve a detecção de compostos ainda não relatados para a espécie, como a vitamina E, o g-tocoferol, esqualeno e estigmasterol. A partir do levantamento estatístico das espécies de maior similaridade química, foram estabelecidos estudos relacionados à extração por maceração (EMAC), extração por Sohxlet (ESOX), extração por ultra-som (USE) e a extração acelerada por solventes (ASE) empregando a mistura solvente etanol:água (70:30 - v/v) para três espécies (V. chamaedryfolia, V. glechomifolia e V. tajuvensis) tendo o ultra-som apresentado melhores resultados, evidenciando a presença de 49 diferentes compostos entre eles polissacarídeos, aminoácidos, monoterpenos, sesquiterpenos, catequina, cumarina, flavona, valepotriato e amidas. A Cromatografia Gasosa foi a ferramenta fundamental na análise de óleos e extratos.<br>The importance of studies on the species of Brazilian Valeriana has been encouraged to obtain viable quantities of phytotherapic compounds that can be economically exploited. This work was carried out to study the chemical composition of volatile oils obtained by the modified Clevenger apparatus of seven species of Valeriana (V. chamaedryfolia, V. eichleriana, V. eupatoria, V. glechomifolia, V. salicariifolia, V. scandens and V. tajuvensis) using the gas chromatography (with flame ionization and mass spectrometry detection) coupled with the use of standards and Kovatz Retention Indices. We identified 243 compounds. Three species of Valeriana had more than 92 % of the identified compounds and two other species, 86 %. The results were compared with data presented for V. officinalis L. Statistically, it was possible to separate them into two groups by correlating the set of variables and multivariate principal component analysis (PCA) selecting the compounds that contributed significantly to the clustering or dispersion of Valeriana species. It was also performed the supercritical fluid extraction (SFE) of the V. tajuvensis using two solvent extractors (CO2 and propane). The yield obtained in SFE was higher than those obtained by hydro-distillation (cleavenger). In these extracts it was achieved some compounds that were not yet reported, such as vitamin E, a -tocopherol, squalene and stigmasterol. From the statistical evaluation of the chemical species, it was established studies on the extraction by maceration (EMAC), Sohxlet (ESOX), ultrasonic (USE) and accelerated solvent (ASE) using a mixture of solvents (ethanol:water - 70:30 v/v) for three species (V. chamaedryfolia, V. glechomifolia and V. tajuvensis). The ultrasound extraction presented better results, showing the presence of 49 different compounds including polysaccharides, amino acids, monoterpenes, sesquiterpenes, catechines, coumarines, flavones, valepotriates and amides. The gas chromatography was the key tool in the analysis of these oils and extracts.
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Russowski, Denise. "Produção de valepotriatos em culturas líquidas de plantas de Valeriana glechomifolia Meyer (Valerianaceae)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/13707.

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Valeriana glechomifolia, espécie endêmica do Sul do Brasil, produz valepotriatos nas partes aéreas e raízes, os quais também ocorrem em rizomas da espécie européia Valeriana officinalis, usada na fabricação de fitoterápicos. Esses metabólitos monoterpênicos estão presumivelmente envolvidos em ação sedativa suave sobre o sistema nervoso central (SNC), bem como apresentam propriedades citotóxicas e antimicóticas. Para melhor compreender o perfil do acúmulo destes metabólitos e a regulação de sua biossíntese, um sistema de cultivo de plantas inteiras de V. glechomifolia em meio líquido foi desenvolvido, e o conteúdo de valepotriatos nestas plantas submetidas a diferentes fatores, tais como presença ou ausência de luz, estresse mecânico (ultrassom – US) e exposição a moléculas sinalizadoras de respostas de defesa como ácido salicílico (AS) e jasmônico (AJ) foi analisado por CLAE. Também foi avaliado o conteúdo de fenóis totais por espectrofotometria, pois recentemente foi descoberta uma possível atividade destes compostos extraídos de raízes de Valeriana officinalis sobre o SNC. Foi observado que o conteúdo de valepotriatos não foi alterado na ausência de luz, enquanto o número de raízes aumentou significativamente. Os demais fatores testados (AS, US e AJ) induziram apenas o acúmulo de valepotriatos, de modo que as vias de biossíntese de valepotriatos e compostos fenólicos parecem ser reguladas de modo independente neste sistema. Ensaios com inibidores específicos das vias de biossíntese plastídica e citossólica da unidade do esqueleto terpênico (isopentenil-pirofosfato - IPP), conduzidos sob condições de elicitação, mostraram reduções similares no conteúdo de valepotriatos, revelando que ambas rotas parecem participar de forma cooperativa e aproximadamente equânime na biossíntese de valepotriatos.<br>Valeriana glechomifolia, an endemic species of southern Brazil, accumulates valepotriates in both shoots and roots. These metabolites are also present in the European species Valeriana officinalis, used in the production of phytomedicines. These monoterpene metabolites have a putative mild sedative effect on the central nervous system (CNS), and display cytotoxic and antifungal activities. In order to better understand the accumulation profile and the regulation of biosynthesis of these metabolites, a liquid culture system for whole-plants of V. glechomifolia was established, and the content of valepotriates in plants submitted to different factors, such as presence or absence of light, mechanical stress (ultrasound – US), and exposure to signaling molecules of defense responses, such as salycilic (SA) and jasmonic acid (JA), was analyzed by HPLC. The content of total phenolics was also evaluated spectrophotometrically since the involvement of flavonoids from roots of V. officinalis in the CNS effects was recently described. The results showed that the content of valepotriates was not altered in the absence of light, whereas the number of roots increased significantly. The various other factors investigated caused increases only in valepotriate contents, indicating that valepotriate and phenolic biosynthesis seem to be independently regulated in this system. Assays with specific inhibitors of the plastidic and cytosolic biosynthetic pathways leading to the terpene carbon skeleton unit (isopentenyl pyrophosphate - IPP), carried out under eliciting conditions, yielded similar reductions in the valepotriate content, suggesting that both routes participate in cooperative and approximately equivalent fashion on valepotriate biosynthesis.
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SUTTER, VERONIQUE. "Analyse physico-chimique d'un extrait sec de valeriana officinalis." Strasbourg 1, 1987. http://www.theses.fr/1987STR10754.

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Müller, Liz Girardi. "Avaliação do envolvimento do sistema monoaminérgico na atividade antidepressiva de um extrato obtido por dióxido de carbono supercrítico de valeriana glechomifolia meyer." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/36120.

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Espécies do gênero Valeriana são tradicionalmente utilizadas no tratamento de insônia e ansiedade. Valepotriatos constituem um importante grupo de metabólitos do gênero que contribui para os efeitos farmacológicos. Trabalhos recentes demonstraram a atividade do tipo antidepressiva de diversas espécies de Valeriana, como V. glechomifolia, nativa do Rio Grande Sul, o que representa uma nova abordagem para o emprego terapêutico do gênero. Objetivos: Investigar o envolvimento da neurotransmissão monoaminérgica na atividade antidepressiva de um extrato de V. glechomifolia obtido por dióxido de carbono supercrítico (SCCO2) e avaliar a influência do tempo e condições de armazenamento no teor de valepotriatos diênicos. Materiais e Métodos: Partes aéreas e subterrâneas de V. glechomifolia foram submetidas a SCCO2 e o extrato obtido foi armazenado (a - 20ºC) seco ou solubilizado em metanol. As concentrações de valepotriatos diênicos foram determinadas, durante 8 meses, através de cromatografia líquida de alta eficiência. A atividade do tipo antidepressiva foi avaliada em camundongos no teste da suspensão pela cauda (TSC) e da natação forçada (TNF). Para a investigação do envolvimento do sistema monoaminérgico, antagonistas de receptores de monoaminas e um inibidor da síntese de serotonina foram administrados. A interação do extrato com antidepressivos convencionais foi avaliada no TNF através da co-administração de doses sub-efetivas. Resultados e Conclusões: V. glechomifolia reduziu a imobilidade dos animais no TSC e TNF, confirmando o potencial antidepressivo. O efeito foi mediado pelos sistemas neurotransmissores noradrenérgico (receptor α2) e dopaminérgico (receptores D1 e D2), o que representa uma ação dual diferenciada. V. glechomifolia potencializou o efeito de imipramina, desipramina e bupropiona no TNF. Em ambas as condições de armazenamento do extrato, observaram-se conversão molecular de valepotriatos diênicos em valtrato. Houve formação de produtos de degradação somente quando o extrato foi armazenado em metanol.<br>Species of the genus Valeriana are traditionally used to treat sleep disorders and anxiety. Valepotriates represent an important group of metabolites that contribute to the pharmacological properties of the genus. Studies have demonstrated the antidepressant-like activity of Valeriana species, like V. glechomifolia, a south Brazil native species, representing a new approach to the therapeutic use of the genus. Objectives: To further investigate the antidepressant-like activity of a V. glechomifolia supercritical carbon dioxide (SCCO2) extract as well as to evaluate the influence of time and storage conditions on diene valepotriates content of this extract. Material and Methods: Aerial and subterranean parts of V. glechomifolia were submitted to SCCO2 and the extract was stored (at -20 ºC) dry or in methanol. Diene valepotriates concentrations were determined through 8 months by high efficiency liquid chromatography. The antidepressant-like activity was evaluated in mice forced swimming test (FST) or tail suspension test (TST). To investigate the involvement of the monoaminergic system in this effect, different groups of mice were pre-treated with monoamine receptors antagonists or an inhibitor of serotonin synthesis. The interaction of the extract with antidepressants was evaluated in the FST by mice co-administration of sub-effective doses. Results and Conclusions: V. glechomifolia was active in the FST and TST, confirming its antidepressant-like effect, which was impaired by adrenergic (α2) and dopaminergic D1 and D2 antagonists, representing a distinct dual action. V. glechomifolia potentiated the antidepressant-like effect of imipramine, desipramine and bupropione in the FST. In both conditions of extract storage, a molecular interconvertion of diene valepotriates into valtrate was observed. Degradation products formation occurred only when the extract was stored in methanol.
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Books on the topic "Valeriani"

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J, Houghton Peter, ed. Valerian: The genus Valeriana. Harwood Academic Press, 1997.

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Pucci, Luigi. Luigi Valeriani Molinari (1758-1828): Un economista tra rivoluzione e restaurazione. Arnaud, 1989.

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Hobbs, Christopher. Valerian: The relaxing and sleep herb. Botanica Press, 1993.

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N, Gorbunov I͡U. Valeriany flory Rossii i sopredelʹnykh gosudarstv: Morfologii͡a, sistematika, perspektivy ispolʹzovanii͡a. Nauka, 2002.

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Febbonio, Muzio. Carseoli e Valeria nei Marsi: Le antiche civiltà dei Carseolani e dei Valeriensi. A. Polla, 2003.

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Dignard, N. La situation de la valériane des tourbières (Valeriana uliginosa) au Québec. Ministère de l'environnement, Direction du patrimoine écologique et du développement durable, 2000.

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Elizabeth, Goudge. Linnets and valerians. Knight, 1989.

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Elizabeth, Goudge. Linnets and Valerians. Puffin Books, 2001.

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Trubbiani, Valeriano. Valeriano Trubbiani: "oficina mundi". Edizioni De Luca, 1997.

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Mills-Macias, Kathi. Valeria's cross. Abingdon Press, 2010.

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Book chapters on the topic "Valeriani"

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Rabbeno, Ugo. "Valeriani, Luigi Molinari (1758–1828)." In The New Palgrave Dictionary of Economics. Palgrave Macmillan UK, 1987. http://dx.doi.org/10.1057/978-1-349-95121-5_1851-1.

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Rabbeno, Ugo. "Valeriani, Luigi Molinari (1758–1828)." In The New Palgrave Dictionary of Economics. Palgrave Macmillan UK, 2018. http://dx.doi.org/10.1057/978-1-349-95189-5_1851.

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Penzkofer, Michael, and Heidi Heuberger. "Valeriana officinalis L. s.l.: Valerian." In Handbook of Plant Breeding. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-38792-1_19.

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Gooch, Jan W. "Valerian." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_12433.

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Paniagua-Zambrana, Narel Y., Rainer W. Bussmann, Javier Echeverría, and Carolina Romero. "Valeriana convallarioides (Schmale) B.B. Larsen Valeriana decussata Ruiz & Pav. Valeriana microphylla Kunth Valeriana micropterina Wedd. Valeriana nivalis Wedd. Valeriana officinalis L. Valeriana pilosa Ruiz & Pav. Valeriana plantaginea Kunth Valeriana rigida Ruiz & Pav. Valeriana scandens L. Valeriana urbanii Phil. Caprifoliaceae." In Ethnobotany of Mountain Regions. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77093-2_294-1.

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Paniagua-Zambrana, Narel Y., Rainer W. Bussmann, Javier Echeverría, and Carolina Romero. "Valeriana convallarioides (Schmale) B.B. Larsen Valeriana decussata Ruiz & Pav. Valeriana microphylla Kunth Valeriana micropterina Wedd. Valeriana nivalis Wedd. Valeriana officinalis L. Valeriana pilosa Ruiz & Pav. Valeriana plantaginea Kunth Valeriana rigida Ruiz & Pav. Valeriana scandens L. Valeriana urbanii Phil. Caprifoliaceae." In Ethnobotany of Mountain Regions. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28933-1_294.

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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott, and R. W. Briddon. "Valeriana spp. (Valeriana officinalis; V. jatamansi)." In Encyclopedia of Plant Viruses and Viroids. Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_979.

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Bährle-Rapp, Marina. "Valeriana fauriei." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_10942.

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Bährle-Rapp, Marina. "Valeriana officinalis." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_10944.

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Bos, R., H. J. Woerdenbag, P. A. G. M. De Smet, and J. J. C. Scheffer. "Valeriana Species." In Adverse Effects of Herbal Drugs. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60367-9_15.

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Conference papers on the topic "Valeriani"

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Leclerc, Sophie, Martin Hill, Jose Burgos, Christian Alzmann, Peter Nofz, and Olivier Martin. "Valerian and the City of a Thousand Planets." In SIGGRAPH '17: Special Interest Group on Computer Graphics and Interactive Techniques Conference. ACM, 2017. http://dx.doi.org/10.1145/3078345.3099611.

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Larina, V. V., Olga Babich, S. Voronova, and Evgeny Chupakhin. "SELECTION OF PARAMETERS FOR OBTAINING EXTRACTS OF VALERIANA OFFICINALIS WITH ANTIOXIDANT PROPERIESS." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-70.

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In this work, were obtained various extracts from the root of Valeriana officinalis and was studied their antioxidant activity by three methods, was studied the content of secondary metabolites of a phenolic nature. Biologically active substances were isolated from the extracts individually.
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Karaj, Shkelqim, Nazim Gruda, Matthias Buscher, and Joachim Müller. "Production of Valeriana officinalis roots in different soil structure in East Albania." In VII South-Eastern Europe Syposium on Vegetables & Potatoes. University of Maribor Press, 2017. http://dx.doi.org/10.18690/978-961-286-045-5.42.

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Aydemir, Onder. "Classification of electroencephalography signals recorded during smelling of valerian and rosewater odors." In 2016 39th International Conference on Telecommunications and Signal Processing (TSP). IEEE, 2016. http://dx.doi.org/10.1109/tsp.2016.7760904.

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Zhao, Li-Hui, Yu-Juan Chen, Feng-Qi Hao, and De-Ming Han. "Study on Active Components on Sleep-Improving Function of Compound Prescription of Valeriana Officinalis." In 2015 Seventh International Conference on Measuring Technology and Mechatronics Automation (ICMTMA). IEEE, 2015. http://dx.doi.org/10.1109/icmtma.2015.254.

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Perez Sabino Juan, F., A. Muñoz Wug Manuel, S. Mérida Reyes Max, et al. "Chemical composition and evaluation of the antimicrobial activity of Valeriana prionophylla Standl. from Guatemala." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608496.

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de Oliveira, Thomás Tabosa, Sebastião Rogério da Silva Neto, Igor Vitor Teixeira, Patricia Takako Endo, and Vanderson Souza Sampaio. "VALERIA: Uma Plataforma para Auxiliar o Diagnóstico e o Monitoramento de Arboviroses." In Anais Estendidos do Simpósio Brasileiro de Sistemas Multimídia e Web. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/webmedia_estendido.2021.17623.

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Arboviruses are Neglected Tropical Diseases (NTDs) that mainly affect developing countries and Brazil is one of them. Such diseases have a negative impact on quality of life of the patients. One of the main challenges in combating these diseases is the difficulty of an accurate diagnosis among the concomitant arborival diseases due the similarity of symptoms. This project proposes VALERIA, a low-cost platform based on machine learning (ML) models for assisting the diagnose of arboviruses in the national scenario. VALERIA is proposed to improve the quality of life of patients, allowing the most appropriate treatment after a diagnose and therefore presenting a great potential of generating local public policies of social impact. A prototype was already developed for diagnosis and is in validation phase by public health specialists.
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Sánchez Gómez-Serranillos, Marta, Elena González-Burgos, and M. Pilar Gómez-Serranillos. "Identification and quality assessment of commercial valerian samples using DNA barcoding and UHPLC-MS." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07285.

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Erdoğan, M., B. Aru, ŞT Yılmaz, E. Yeşilada, G. Yanıkkaya Demirel, and H. Kırmızıbekmez. "Isolation of cytotoxic compounds from the underground parts of Valeriana sisymbriifolia Vahl. through activity-guided fractionation." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736775.

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Atienza Fuente, Javier. "The Local Quarries of the Ancient Roman City of Valeria (Cuenca, Spain)." In XI International Conference of ASMOSIA. University of Split, Arts Academy in Split; University of Split, Faculty of Civil Engineering, Architecture and Geodesy, 2018. http://dx.doi.org/10.31534/xi.asmosia.2015/05.08.

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Reports on the topic "Valeriani"

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Netz, Nicolai. Welchen Einfluss hat internationale Mobilität auf wissenschaftliche Karrieren? Ein Forschungsüberblick. Deutscher Akademischer Austauschdienst (DAAD), 2021. http://dx.doi.org/10.46685/daadstudien.2021.01.

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In einem systematischen Review werten Nicolai Netz, Svenja Hampel und Valeria Aman 96 empirische Studien zum Einfluss internationaler Mobilität auf wissenschaftliche Karrieren aus. Die Analyse dieses noch jungen, aber in den letzten Jahren sehr dynamischen Forschungsfeldes zeigt, dass internationale Mobilität zum Ausbau wissenschaftlicher Netzwerke beiträgt. Zudem gibt es Hinweise, dass internationale Mobilität die wissenschaftliche Produktivität und Rezeption, das heißt die Anzahl der Publikationen und Zitationen, erhöhen kann. Auch den beruflichen Aufstieg kann internationale Mobilität begünstigen. Sie scheint jedoch ebenso mit durchschnittlich längeren befristeten Beschäftigungsverhältnissen einherzugehen. Andere Karrieredimensionen – wie die Kompetenz- und Persönlichkeitsentwicklung, das wissenschaftliche Fachwissen, der Zugang zu Forschungsinfrastruktur und -finanzierung sowie Reputationsgewinne – wurden erst deutlich seltener und auf Basis weniger belastbarer Forschungsdesigns untersucht.
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