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1

Li, Yu-Bing, Xue-Zhong Zhou, Run-Shun Zhang, et al. "Detection of Herb-Symptom Associations from Traditional Chinese Medicine Clinical Data." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/270450.

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Background. Traditional Chinese medicine (TCM) is an individualized medicine by observing the symptoms and signs (symptoms in brief) of patients. We aim to extract the meaningful herb-symptom relationships from large scale TCM clinical data.Methods. To investigate the correlations between symptoms and herbs held for patients, we use four clinical data sets collected from TCM outpatient clinical settings and calculate the similarities between patient pairs in terms of the herb constituents of their prescriptions and their manifesting symptoms by cosine measure. To address the large-scale multiple testing problems for the detection of herb-symptom associations and the dependence between herbs involving similar efficacies, we propose a network-based correlation analysis (NetCorrA) method to detect the herb-symptom associations.Results. The results show that there are strong positive correlations between symptom similarity and herb similarity, which indicates that herb-symptom correspondence is a clinical principle adhered to by most TCM physicians. Furthermore, the NetCorrA method obtains meaningful herb-symptom associations and performs better than the chi-square correlation method by filtering the false positive associations.Conclusions. Symptoms play significant roles for the prescriptions of herb treatment. The herb-symptom correspondence principle indicates that clinical phenotypic targets (i.e., symptoms) of herbs exist and would be valuable for further investigations.
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2

Neeraja, P.V, and Margaret Elizabeth. "Eclipta alba (L.) Hassk: A Valuable Medicinal herb." International Journal of Current Pharmaceutical Review and Research 2, no. 4 (2012): 188–97. https://doi.org/10.5281/zenodo.12698283.

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Herbs are staging a comeback and herbal ‘renaissance’ is happening all over the globe. Theherbal products today symbolise safety in contrast to the synthetics that are regarded asunsafe to human and environment. Although herbs had been priced for their medicinal,flavorings and aromatic qualities for centuries, the synthetic products of the modern agesurpassed their importance, for a while. The plant Eclipta alba Hassk (Asteraceae) known forits medicinal values in alternative systems of (Ayurvedic, Unani, Sidha, Homeopathy,Chines) holistic health and herbal medicine. Eclipta alba Hassk is reported to possessHepatoprotective, antimicrobial, anti-inflammatory, analgesic, immuno-modulatory, antiviraland promoter for blackening and growth of hair. Important source of chemicals iswedelolactone, demethylwedelolactone exhibit antihepatotoxic activities. This review articleelucidates the evidence based information regarding the photochemistry and pharmacologicalactivity of this plant.
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Sarkar, Manjusha, and Satyesh Chandra Roy. "Rapid Scale Micropropagation of Glycyrrhiza Glabra L. ( Leguminoseae) A Valuable Medicinal Herb." International Journal of Scientific Research 3, no. 3 (2012): 20–22. http://dx.doi.org/10.15373/22778179/march2014/7.

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4

R., Mohanapriya, and Vanathi P. "Pharmacological Insights into Trichodesma indicum: A Medicinally Valuable Herb." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 10 (2024): 794–804. https://doi.org/10.5281/zenodo.13908174.

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<strong>Background:</strong>&nbsp;The present study was aimed to investigate the pharmacological properties of a medicinally significant herbal species,&nbsp;<em>Trichodesma indicum</em>. Phytochemical analysis of methanol, ethanol, acetone, petroleum ether and aqueous extracts of&nbsp;<em>T.indicum&nbsp;</em>was explored. &nbsp; <strong>Methodology:&nbsp;</strong>Antibacterial activity of these solvent extracts of&nbsp;<em>T.indicum&nbsp;</em>was determined against the test organisms (<em>Escherichia coli, Klebsiella&nbsp;</em>sp.,&nbsp;<em>Pseudomonas aeruginosa, Salmonella&nbsp;</em>sp. and&nbsp;<em>Proteus&nbsp;</em>sp.) using well diffusion method. Anti-oxidant activity for three different standard concentrations (100, 200 and 300&mu;g/ml) of&nbsp;<em>T.indicum&nbsp;</em>methanol extract was determined using DPPH, superoxide scavenging activity and nitric oxide scavenging activity assays. Wound healing efficacy of&nbsp;<em>T.indicum&nbsp;</em>methanol extract was investigated using standard&nbsp;<em>in vitro</em>&nbsp;wound scratch assay. &nbsp; &nbsp; <strong>Results:</strong>&nbsp;Phytochemical analysis explored the presence of alkaloids, phenols, flavonoids, tannins and terpenoids in higher level for methanol extracts of&nbsp;<em>T.indicum.&nbsp;</em>Antibacterial activity of the methanol extracts of&nbsp;<em>T.indicum&nbsp;</em>exhibited inhibitory zones ranging from 27 to 29mm against all the test bacteria; which was comparatively maximum than other solvent extracts. Hence methanol extract was used for anti-oxidant activity and wound healing studies. Anti-oxidant DPPH assays revealed IC50 value of 292.19&micro;g/ml for&nbsp;<em>T. indicum&nbsp;</em>extract. Superoxide scavenging activity expressed IC50 value of 192.34&micro;g/ml; and nitric oxide scavenging activity showed IC50 value of 224.64&micro;g/ml respectively. The self-wound healing ability of&nbsp;<em>T.indicum</em>&nbsp;extracts showed positive cell migration and cell proliferation after 12&nbsp;<sup>th&nbsp;</sup>and 24<sup>th</sup>&nbsp;hours indicating the wound closure under&nbsp;<em>in vitro</em>&nbsp;conditions. &nbsp; <strong>Conclusion &amp; recommendation:</strong>&nbsp;The research showed promising results and evidenced pharmacological properties of the selected medicinally significant&nbsp;<em>T.indicum.&nbsp;</em>Further studies like anti-diabetic, antifungal and antiviral properties shall be considered based on the above results.
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5

Yang, Ming, Jianghe Luo, Yan Li, and Limian Xu. "Systems Pharmacology-Based Research on the Mechanism of Tusizi-Sangjisheng Herb Pair in the Treatment of Threatened Abortion." BioMed Research International 2020 (July 21, 2020): 1–15. http://dx.doi.org/10.1155/2020/4748264.

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Threatened abortion (TA) is a common complication with high incidence in the first trimester of pregnancy, which will end in miscarriage if not treated properly. The Chinese herbs Cuscutae Semen (Tusizi in Chinese) and Herba Taxilli (Sangjisheng in Chinese) first recorded in the ancient classic medical book Shennong Bencao Jing are effective and widely used as an herb pair for the treatment of TA, while the active ingredients and the functional mechanism of Tusizi-Sangjisheng herb pair treating TA are still unknown. In order to exploit the relationship between those two herbs and TA, systems pharmacology analysis was carried out in this study. A total of 75 ingredients of Tusizi-Sangjisheng were collected from Traditional Chinese Medicine System Pharmacology Database and Analysis Platform (TCMSP). 12 bioactive compounds were screened, and 153 directly related targets were predicted by systematic models. Besides, Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were used to systematically explore the potential mechanisms of Tusizi-Sangjisheng treating TA. Meanwhile, Compound-Target (C-T), Target-Disease (T-D), and Target-Pathway (T-P) networks were constructed to further quest the underlying functional mechanisms of Tusizi-Sangjisheng. As a result, 31 targets and 3 key pathways were found to be directly related to TA that includes mitogen-activated protein kinases (MAPKs), phosphatidylinositol-3-kinase/protein kinase B (PI3K-Akt), and transforming growth factor-β (TGF-β) signaling pathways. The results in this study may provide some valuable clues about the molecular mechanisms of the efficient Chinese herb pair Tusizi-Sangjisheng in the treatment of TA.
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Ahmad, Asrar, Mohd Afsahul Kalam, and Zaffar Hussain. "SANKHAHOLI (EVOLVULUS ALSINOIDES LINN): A VALUABLE HERB OF UNANI MEDICINE." Journal of Biological & Scientific Opinion 10, no. 4 (2022): 45–48. http://dx.doi.org/10.7897/2321-6328.104159.

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Sankhaholi (Evolvulus alsinoides) is a small perennial herb belonging to the family Convolvulaceae. It is also known as Vishnukranti (Sanskrit), Sankhavalli (Marathi) and Vishnukraandi (Tamil). According to Unani Medicine the notable medicinal properties reported for the treatment of flatulence, haemorrhoids, diabetes, frequency of micturition, burning micturition, gonorrhea, syphilis, and other renal and bladder diseases. It contains pentatriacontane, triacontane and betasitosterol. Various pharmacological properties reported are Antihypertensive, Antioxidant, Anti Stress, Hypolipidaemic etc. This review presents a detailed survey of the literature on the identification of plant, phytochemistry and medicinal properties from the perspective of Unani Medicine and pharmacological studies.
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7

Rey Benayas, J. M., A. Fernández, and A. Aubenau. "Clipping herbaceous vegetation improves early performance of planted seedlings of the Mediterranean shrub <i>Quercus coccifera</i>." Web Ecology 7, no. 1 (2007): 120–31. http://dx.doi.org/10.5194/we-7-120-2007.

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Abstract. We tested how the conditions resulting from alternative management strategies addressed to mitigate abiotic and biotic limitations to plant establishment affect the performance of planted Quercus coccifera seedlings. This species is a xerophytic and heliophillous Mediterranean shrub, of interest for the restoration of abandoned farmland. We hypothesised that release from herb competition by clipping would allow Q. coccifera seedlings to cope more efficiently with water shortage by adjusting their mass allocation pattern. We established three environments of herb competition: absence of competition (AC), reduced competition by clipping (RC), and total competition (TC); and applied two irrigation treatments: low and high irrigation. We measured soil moisture at different depths, above- and below-ground herb biomass, and evaluated seedling responses, such as mortality, growth, biomass allocation, and morphological and physiological features. The TC treatment reduced water availability more than the RC treatment, in agreement with the highest water stress of seedlings under TC conditions. Irrigation increased above- and below-ground herb biomass, whereas clipping reduced herb production. Release of herb competition by clipping increased seedling survivorship by one order of magnitude and resulted in a growth rate comparable to the absence of competition. This growth was mostly related to carbon gain allocated to roots. The competition intensity imposed by treatments was related to a parallel reduction in total plant leaf area, biomass allocated to leaves and shoot:root ratio, and an increase in biomass allocated to roots and leaf mass area. The negative effects of herbs on Q. coccifera seedlings seem the result of competition for both water and light, in contrast with previous research with more mesic Quercus species, for which competition is primarily for water. Clipping of herbs is a feasible technique that greatly improved seedling performance, and thus a valuable alternative to herbicide application, common in native plantations aimed at restoring Mediterranean farmland.
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8

Ekiert, Halina, Joanna Pajor, Paweł Klin, Agnieszka Rzepiela, Halina Ślesak, and Agnieszka Szopa. "Significance of Artemisia Vulgaris L. (Common Mugwort) in the History of Medicine and Its Possible Contemporary Applications Substantiated by Phytochemical and Pharmacological Studies." Molecules 25, no. 19 (2020): 4415. http://dx.doi.org/10.3390/molecules25194415.

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Artemisia vulgaris L. (common mugwort) is a species with great importance in the history of medicine and was called the “mother of herbs” in the Middle Ages. It is a common herbaceous plant that exhibits high morphological and phytochemical variability depending on the location where it occurs. This species is well known almost all over the world. Its herb—Artemisiae vulgaris herba—is used as a raw material due to the presence of essential oil, flavonoids, and sesquiterpenoids lactones and their associated biological activities. The European Pharmacopoeia has listed this species as a potential homeopathic raw material. Moreover, this species has been used in traditional Chinese, Hindu, and European medicine to regulate the functioning of the gastrointestinal system and treat various gynecological diseases. The general aim of this review was to analyze the progress of phytochemical and pharmacological as well as professional scientific studies focusing on A. vulgaris. Thus far, numerous authors have confirmed the beneficial properties of A. vulgaris herb extracts, including their antioxidant, hepatoprotective, antispasmolytic, antinociceptive, estrogenic, cytotoxic, antibacterial, and antifungal effects. In addition, several works have reviewed the use of this species in the production of cosmetics and its role as a valuable spice in the food industry. Furthermore, biotechnological micropropagation of A. vulgaris has been analyzed.
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9

NagaSree, Punem Vani* Shankar Priyanka Mishra Anu Ram Kailash Sagar Prashant. "Plumbago Zeylanica: A Valuable Resource for Natural Health Products." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1007–14. https://doi.org/10.5281/zenodo.15181835.

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Chitrak, <em>Plumbago zeylanica Linn.,</em> is well known as a medicinal herb with substantial health benefits. This is a perennial herb, which is a member of the Plumbaginaceae family. The plant has a long-term&nbsp; use in traditional Indian medicine as well as other regional medicine. Chitrak significance has increased because of its various pharmacological qualities. The plant can therapeutically act as an anti-inflammatory, anti-obesity, analgesic effects, anti-cancer, anti-fertility effects, and anti-blood coagulate. The plant parts and roots have been used since centuries in ayurvedic medicine to cure conditions like arthritis, leprosy, skin conditions, and digestive problems. The promising effects of this plant are attributed to an important bio-active compound called Plumbagin and phytochemicals such as Flavonoids, Alkaloids, and some key elements that the leaf possess. Despite its extensive medicinal benefits, caution is advised as overuse can lead to adverse effects.&nbsp; Even in today&rsquo;s era of Modern Medicine, many individuals rely on consumption of herbal medicine. To meet the current demand and to support the health of individuals, the review aims to seek the attention of future researchers to fully utilize the naturally available resources into a natural remedy such as herbal formulations like decoction, tea, or nutraceuticals for treating the different health aliments around the world.
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10

Baskaran, P., and N. Jayabalan. "An efficient micropropagation system for Eclipta, alba—A valuable medicinal herb." In Vitro Cellular & Developmental Biology - Plant 41, no. 4 (2005): 532–39. http://dx.doi.org/10.1079/ivp2005667.

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11

Nandita, Gautam, KK Shivalingesh, Singh Arjun, Singh Varnika, and Rajpoot Deepshikha. "Herbo-dentistry- A review." Journal of Dental Problems and Solutions 9, no. 1 (2022): 006–11. http://dx.doi.org/10.17352/2394-8418.000109.

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Phytotherapy is the study of the use of extracts from the natural origin as medicines or health-promoting agents. Plant products have long been used in dentistry as part of various dental materials right from impression materials to eugenol, which forms an integral part of the dental clinic. The use of herbs in dental practice is not limited to only material sciences. A single herb shows a variety of effects like anti-inflammatory, antibacterial, antifungal activity, and many more. Hence the incorporation of these herbs in dental practice will prove to be a valuable adjunct to dental treatment.
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12

Kumari, Vidyan. "Ethnopharmacological Importance of Gymnema sylvestre." European Journal of Medicinal Plants 35, no. 6 (2024): 224–33. http://dx.doi.org/10.9734/ejmp/2024/v35i61221.

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Gymnema sylvestre is one of the valuable medicinally important herbs that belong to family Apocynaceae. G. Sylvester is a woody climber mostly found in India, Srilanka, China, Indonesia, Malaysia and Tropical Africa. Traditionally the leaf of the herb is used as antidiabetic, antihelmentic, antiobesity, anti-inflammatory, hypolipidaemic, antivenom and antimicrobial. The herb is used by some ethnic community in constipation, haemorrhoids, jaundice, leucoderma, asthma, bronchitis, cardiac problems and dyspepsia. Most important phytochemicals of the plant are gymnemic acid, deacyl gymnemic acid and gymnemagenol which help in the controlling of blood cholesterol, triglyceride levels, inflammation and body weight. The present review aims to document the traditional and modern pharmacological uses of the plant to provide better scope for further experiments and future application. The botanical description, cultivation practices, phytochemical constituents and safety issues of the plant has also been described in the chapter.
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Saeidnia, Soodabeh. "Future Position of Crocus sativus as a Valuable Medicinal Herb in Phytotherapy." Pharmacognosy Journal 4, no. 27 (2012): 71. http://dx.doi.org/10.5530/pj.2012.27.12.

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14

S Sonawane, Vaishnavi, Sonal B. shinde, and Vaibhavi S Joshi. "Unveilling the healing properties of Euphorbia nerrifolia in treatment of piles." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 694–99. https://doi.org/10.35629/4494-0906694699.

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Plants have been valuable because they can be utilised as medical herbs to cure a variety of diseases. Euphorbia neriifolia is one such plant that produces toxic milky white latex, a natural herb with wound healing property of piles. It may promote wound healing by enhancing collagen synthesis and tissue repair.Phenol is the main chemical compound use for the wound healing which include euphol, taraxerol, nerifoliol,etc. In combination it is effective remedy for managing and treating piles. The goal of the review is to refresh our understanding of Euphorbia neriifolia, including its uses, distribution, harmful effects, chemical composition, mechanism etc.
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Sunita, Verma, and Rajbala. "LUFFA CYLINDRICA- SPONGE GOURD (CUCURBITACEAE): A MEDICINAL GREEN HERB." International Journal of Applied and Advanced Scientific Research 3, no. 1 (2018): 53–55. https://doi.org/10.5281/zenodo.1158025.

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A medicinal herb as potential source of therapeutic aids has attained a significant role in health system. Genus <em>Luffa </em>belongs to Cucurbitaceae family is a tropical or sub tropical and warm climate fast growing plant. <em>Luffa cylindrica</em> as a medicinal plant has been widely employed in treatment of many diseases. It used as edible vegetable. The present paper is an attempt to provide a detailed taxonomy, phyto-chemical characters, medicinal and pharmacological potential of this valuable herb plant.
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Li, Ya-Li, Yan-Zhu Zhu, Pei-He Zheng, et al. "Potentially Harmful Maillard Reaction Products in Food and Herb Medicines." Journal of Food Quality 2021 (January 5, 2021): 1–11. http://dx.doi.org/10.1155/2021/1798936.

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The Maillard reaction is of great significance in food, herb medicines, and life processes. It is usually occurring during the process of food and herb medicines processing and storage. The formed Maillard reaction productions (MRPs) in food and herb medicines not only generate a large number of efficacy components but also generate a small amount of harmful substance that cannot be ignored. Some of the MRPs, especially the advanced glycation end products (AGEs) are concerning humans, based on the possibility to induce cancer and mutations in laboratory animals. Numerous studies have been reported on the formation, analysis, and control of the potentially harmful MRPs (PHMRPs). Therefore, the investigation into the formation, analysis, and control of PHMRPs in food and herb medicines is very important for improving the quality and safety of food and herb medicines. This article provides a brief review of the formation, analysis (major content), and control of PHMRPs in food and herb medicines, which will provide a base and reference for safe processing and storage of food and herb medicines. Practical Applications. The formed Maillard reaction productions in food and herb medicines not only generate a large number of functional components but also generate a small amount of harmful substance that cannot be ignored. This contribution provides a brief review on the formation (including the correlative studies between MRs and the PHMRPs, mechanisms, and the main pathways); analysis (major content, pretreatment for analysis, qualitative and quantitative analysis, and structural identification analysis); and control (strategies and mechanisms) of PHMRPs in food and herb medicines, which will provide a solid theoretical foundation and a valuable reference for safe processing and storage for food and herb medicines.
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Wang, Lidong, Yin Zhang, Yun Zhang, Xiaodong Xu, and Shihua Cao. "Prescription Function Prediction Using Topic Model and Multilabel Classifiers." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/8279109.

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Determining a prescription’s function is one of the challenging problems in Traditional Chinese Medicine (TCM). In past decades, TCM has been widely researched through various methods in computer science, but none concentrates on the prediction method for a new prescription’s function. In this study, two methods are presented concerning this issue. The first method is based on a novel supervised topic model named Label-Prescription-Herb (LPH), which incorporates herb-herb compatibility rules into learning process. The second method is based on multilabel classifiers built by TFIDF features and herbal attribute features. Experiments undertaken reveal that both methods perform well, but the multilabel classifiers slightly outperform LPH-based method. The prediction results can provide valuable information for new prescription discovery before clinical test.
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Rastogi, Nidhi, and Alind Rastogi. "Phytosociological analysis of the restored Sal (Shorea robusta) plantations and natural sal forest of Tripura." Indian Journal of Forestry 30, no. 4 (2007): 377–85. http://dx.doi.org/10.54207/bsmps1000-2007-1399ll.

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Among the existing activities in managing tropical forests, conservation efforts for Sal (Shorea robusta) forest in Tripura have virtually offered very valuable results. 68 plant species belonging to 41 taxonomic families were identified in such study areas. Remarkable dissimilarity between the stands of the restored coppice crop (7 and 16 years) and natural forest (approx. 45 years) was observed. Ground flora of young coppice crop was enriched with herb species while the density of shrubs and woody climbers was higher in the natural stand. Density per ha of herbs, shrubs and trees varied between 168000-497800, 18800-42112, 1100-2975 respectively. Total basal cover (m2 per ha) of herbs, shrubs and trees ranged between 0.524-0.941, 0.138-0.952, 2.333- 86.295 respectively. In the shrub layer 24.9% to 46.2% of the density and 53.4-81.6% of the Total Basal Cover (TBC) was shared by saplings belonging to economically and medicinally important tree species. It also indicates the regeneration potential of the area. Diversity index (Shannon Wiener Index) varied between 0.918- 0.967 for herbs, 0.743-0.876 for shrubs and 0.859 for trees. Values of Jaccard Similarity index were between 33-80% in herb layer, 22-48% in shrub layer, 14-100% in tree layer. The study brings out that the distribution of most of the species was random to contagious. Important flora viz. Smilax zeylanica, Vitex peduncularis, Ziziphus rugosa were the common species of the plant community on account of intact natural habitat.
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Chandradevan, Machap, Sanimah Simoh, Ahmed Mediani, Nor Hadiani Ismail, Intan Safinar Ismail, and Faridah Abas. "UHPLC-ESI-Orbitrap-MS Analysis of Biologically Active Extracts from Gynura procumbens (Lour.) Merr. and Cleome gynandra L. Leaves." Evidence-Based Complementary and Alternative Medicine 2020 (January 27, 2020): 1–14. http://dx.doi.org/10.1155/2020/3238561.

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This study aimed to determine the total phenolic content, DPPH scavenging, α-glucosidase, and nitric oxide (NO) inhibition of Gynura procumbens and Cleome gynandra extracts obtained with five different ethanolic concentrations. The findings showed that the 100% ethanolic extract of G. procumbens had the highest phenolic content and the lowest IC50 values for DPPH scavenging and NO inhibition activity compared to the properties of the other extracts. For C. gynandra, the 20% and 100% ethanolic extracts had comparably high total phenolic contents, and the latter possessed the lowest IC50 value in the NO inhibition assay. In addition, the 20% ethanolic extract of C. gynandra had the lowest IC50 value in the DPPH scavenging assay. However, none of the extracts from either herb had the ability to inhibit α-glucosidase enzyme. Pearson correlation analysis indicated a strong relationship between the phenolic content and DPPH scavenging activity in both herb extracts. A moderately strong relationship was also observed between the phenolic content and NO inhibition in G. procumbens extracts and not in C. gynandra extracts. The UHPLC-ESI-Orbitrap-MS revealed major phenolics from the groups of hydroxycinnamic acids, hydroxybenzoic acids, and flavonoid derivatives from both herbs, which could be the key contributors to their bioactivities. Among the identified metabolites, 24 metabolites were tentatively assigned for the first time from both species of studied herbs. These two herbs could be recommended as prospective natural products with valuable medicinal properties.
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Alam, Dr Md Izhar, and Dr Abdul Nasir Ansari Ansari. "Therapeutic and Nutritional Properties of Fenugreek in Unani Medicine: A Short Review." International Journal of Medical and Biomedical Studies 7, no. 4 (2023): 52–58. http://dx.doi.org/10.32553/ijmbs.v7i4.2704.

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Fenugreek is a wonderful herb with impressive therapeutic and nutritional benefits and has been in use for thousands of years in Ayurveda, Unani, and Chinese medicine both as medicine and spice. It is a rich source of iron, magnesium, alkaloids, saponins, flavonoids and steroids. Recent researches have highly explored its antidiabetic, anticarcinogenic, hypocholesteremic, anti-oxidant, and immunological actions. Seeing the volume and trend of research on the said herb, least work has been done with reference to this valuable plant in Unani medicine. It is a sincere effort of authors to accurately present the invaluable benefits mentioned in Unani classical literature.
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P, Thangavel, John Britto S, and R. Senthilkumar S. "Adventitious shoot regeneration from leaf explants of the valuable medicinal herb Plectranthus barbatus Andrews." African Journal of Biotechnology 10, no. 43 (2013): 8562–69. http://dx.doi.org/10.5897/ajb10.1262.

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22

Behera, Shashikanta, Kumari Monalisa, Rajesh K. Meher, et al. "Phytochemical fidelity and therapeutic activity of micropropagated Curcuma amada Roxb.: A valuable medicinal herb." Industrial Crops and Products 176 (February 2022): 114401. http://dx.doi.org/10.1016/j.indcrop.2021.114401.

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23

Darshan, Hosmath*. "Therapeutic Potential and Multifaceted Benefits of Piper Betle Linn: A Comprehensive Review." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1500–1509. https://doi.org/10.5281/zenodo.15037095.

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A plant in the Piperaceae family, the piper betle has heart-shaped leaves that are deep green in color. Paan, or "Green Gold," is another name for piper betle leaves in India. It contains a lot of vitamins, minerals, nutrients, antioxidants, and phytochemicals. It is a valuable herb with numerous health benefits. It is herbal drug described by ancient charayas, nighantus and Rajnighantu. It is widely used in community for their non side effects and long-lasting benefits. Its extract used for mouthwash breath cleansing and treating various diseases. Its phytochemical includes phenolic, alkaloids, terpenoids, flavonoids, tannins, saponins, and sugar etc. Its antimicrobial, antioxidant, anti-cancer, and anti-inflammatory pharmacological qualities have all been investigated. This review article focuses on phytochemical of active constituents, pharmacological properties and anti-microbial effect of Piper betle Linn.
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Bączek, Katarzyna, Olga Kosakowska, Jarosław L. Przybył, and Zenon Węglarz. "Accumulation of phenolic compounds in the purple betony herb (Stachys officinalis L.) originated from cultivation." Herba Polonica 62, no. 2 (2016): 7–16. http://dx.doi.org/10.1515/hepo-2016-0007.

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Summary Introduction: Purple betony (Stachys officinalis L., Lamiaceae) is a perennial of versatile medicinal usage. Nowadays, in Poland betony herb is collected exclusively from wild growing plants. Decreasing number of its natural sites results in lack of the herb supply and thus, in its limited usage. Objective: The aim of the study was to determine the effects of the age of plant and term of raw material harvest on its yield and quality in cultivation conditions. Methods: The observations were carried out on 2- and 3-year-old plants. During vegetation the herb was collected for four times. The raw material was subjected to chemical analysis. Tannins (as pyrogallol equivalent) were determined according to Polish Pharmacopoeia, phenolic acids and flavonoids – by HPLC. Results: The mass of herb, both in the second and third year, had increased from the beginning of vegetation up to seed setting. The highest content of tannins was found in the herb collected at the vegetative stage of plant development (2.05% in the second and 2.91% in the third year). Four phenolic acids (chlorogenic, ferulic, caffeic and rosmarinic acids) and five flavonoid compounds (orientin, luteolin-7-glucoside, apigenin-7-glucoside, apigenin-3-glucoside, apigenin) were identified in the obtained raw materials. In these groups, the dominant compounds were caffeic acid and apigenin. The highest content of caffeic acid was found at the beginning of plant vegetation, whereas apigenin – at the stage of full blooming and seed setting. Conclusion: In cultivation conditions, purple betony produces high mass of herb which may be used as a valuable raw material in herbal industry.
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Pisal, Shriraj. "Medicinal Herb Identification Using CNN Model." International Journal for Research in Applied Science and Engineering Technology 12, no. 5 (2024): 5022–27. http://dx.doi.org/10.22214/ijraset.2024.62716.

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Abstract: Automated herb identification plays a crucial role in various industries such as cosmetics, medicine, and food, where the need to accurately identify different plant species is essential. However, existing methods often face challenges when dealing with complex backgrounds and a wide variety of patterns, especially in wild environments. In response to these challenges, we propose an innovative convolutional neural network (CNN) model that incorporates two key components: the Part- Information Perception Module and the Species Classification Module. The Part-Information Perception Module in our model is designed to focus the model's attention on the relevant parts of the herb, effectively suppressing background noise. This mechanism allows the model to better discern the distinctive features of the herb itself, improving overall accuracy. Furthermore, we employ depthwise separable convolution and label smoothing techniques to reduce model complexity and minimize the impact of labelling inconsistencies, enhancing both efficiency and reliability. To validate the effectiveness of our model, we conducted experiments using a diverse dataset of herb images. The results demonstrate a significant improvement in accuracy and model efficiency compared to existing methods, making it a valuable tool for herb identification in challenging environments. In addition to herb identification, we also address the complex task of recognizing medicinal plant species. To facilitate this, we have created a dataset comprising image features of plant leaves, enabling the development of an automated recognition system using machine learning classifiers. Our experiments show that the classifiers achieve an impressive average accuracy rate of over 97%, highlighting the potential of our approach in accurately identifying medicinal plant species.
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NASTASI, LOUIS F., and ANDREW R. DEANS. "Review of the world genera of Phanacidini (Hymenoptera: Cynipoidea: Cynipidae), with the first record from China and a new tribal diagnostic character." Zootaxa 5621, no. 4 (2025): 401–19. https://doi.org/10.11646/zootaxa.5621.4.1.

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We review the genera of Phanacidini and provide updated diagnoses for each genus and a new key to the four genera. We also redescribe the enigmatic herb gall wasp Diakontschukia saussureae Diakontschuk, 2001 (Hymenoptera: Cynipidae: Phanacidini), based on a specimen collected in Haopingsi Nature Reserve, China. This is the first record of the tribe Phanacidini in China. Lastly, we provide extensive commentary on the validity of diagnostic characters that have been used for Phanacidini relative to other herb gall wasp tribes. We carried out a survey of Aulacideini, Aylacini, and Phanacidini to identify whether the length of F1 relative to F2 was of diagnostic value at the tribal level, finding that F1 was always conspicuously longer than F2 in Phanacidini and Aylacini but at most subequal to F2 in Aulacideini, suggesting that this is indeed a valuable character for diagnosing herb gall wasp tribes. Other characters discussed are the closure of the marginal cell and the dimensions of the mesopectus.
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Bhukta, Pallishree, Deepankar Rath, Gurudutta Pattnaik, Biswakanth Kar, and Santosh Kumar Ranajit. "A Comprehensive Review on Promising Phytopharmacological Applications of Chamomile Flower." Asian Journal of Chemistry 33, no. 11 (2021): 2864–70. http://dx.doi.org/10.14233/ajchem.2021.23390.

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Chamomile (Matricaria recutita L., Chamomilla recutita L., Matricaria chamomilla) is one of the most favoured single ingredient herbs. Chamomile tea is prepared by brewing the dried flower heads which has been used as traditional remedy. It is a crop introduced into India, mainly grown in Assam, Uttar Pradesh, Jammu &amp; Kashmir states of India. The valuable unknown properties of this multipurpose herb should be explored to determine the therapeutic properties of its different parts, extracts, oils, etc. The flowers constitute many phenolic compounds like flavonoids, apigenin, patuletin, glucosides, luteolin and quercetin as main components. This herb is used as an antioxidant, antidepressant, antidiarrheal, antimicrobial, anti-inflammatory, antidiabetic, anticarcinogenic and hepatoprotective agents. In addition to that, it is also useful in treatment of gastrointestinal disorders, premenstrual syndrome, knee osteoarthritis andulcerative colitis. Matricaria Recutita chamomilla L. is used for both therapeutically and non-therapeutically around the globe that precipitate its remarkable worth. Chamomile contents of essential oils are widely used in aromatherapy and cosmetics. Most popular chamomile preparation is herbal tea which has been developed and consumed by more than one million cups per day across the globe. This review article briefs about the therapeutic efficiency along with phytology and cultivation techniques.
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Dreger, Mariola, Jolanta Wegenke, Joanna Makowiecka, Tomasz Michalik, and Karolina Wielgus. "Application of multi-shoots cultures in micropropagation of willow herb (Chamaenerion angustifolium (L.) Scop.)." Herba Polonica 62, no. 3 (2016): 28–39. http://dx.doi.org/10.1515/hepo-2016-0015.

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Summary Introduction: Willow herb (Chamaenerion angustifolium (L.) Scop. syn. Epilobium angustifolium L. from Onagraceae family is a valuable medicinal plant that has been used in the treatment of urogenital disorders including BPH (Benign Prostatic Hypertrophy). The raw material is a rich source of polyphenols as well as steroids, triterpenoids and fatty acids. Due to frequent interspecific hybridization, plants collected in wild display a very diverse and variable content of active compounds. This poses a challenge in obtaining high quality and homogenous raw material. Application of the in vitro cultures and micropropagation techniques may offer a solution for alternative methods of cultivation. Objective: This work presents preliminary results of the first implementation of in vitro cultures of willow herb to obtain material for medicinal purposes. Methods: Sterile seedlings were donors of explants, which were used for induction of multi-shoots culture according to a modified protocol described by Turker and co-workers. Statistical analysis was used for assessment of significance of differences among variables. Results: Six different genotypes (lines) originating from root explants were chosen for clonal propagation. Efficiency of the elaborated method was 16–20 shoots per explant. Finally, over 3000 acclimatized plants were obtained and used for field crops. Conclusions: The use of Ch. angustifolium in vitro cultures can contribute to the introduction of this valuable herb for field crops and increase the availability of the raw material for food and pharmaceutical industries.
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Michalak, Monika, Martyna Zagórska-Dziok, Marta Klimek-Szczykutowicz, and Agnieszka Szopa. "Phenolic Profile and Comparison of the Antioxidant, Anti-Ageing, Anti-Inflammatory, and Protective Activities of Borago officinalis Extracts on Skin Cells." Molecules 28, no. 2 (2023): 868. http://dx.doi.org/10.3390/molecules28020868.

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In this study, methanol and water–methanol extracts of borage (Borago officinalis) herb dried using various methods were analysed for their phenolic profile and biological activity. Twelve compounds, including flavonoids (astragalin, kaempferol 4-glucoside, rutoside, and vitexin) and phenolic acids (caffeic, chlorogenic, 3,4-dihydroxyphenylacetic, ferulic, p-hydroxybenzoic, protocatechuic, rosmarinic, and syringic), were determined qualitatively and quantitatively in B. officinalis extracts by the HPLC-DAD method. The highest total flavonoid content was confirmed for the methanol extract from the hot-air-dried herb, while the methanol extract from the air-dried herb was most abundant in phenolic acids. The results of in vitro tests on human keratinocytes (HaCaT) and fibroblasts (BJ) showed that the extracts were able to reduce the intracellular level of reactive oxygen species in skin cells. Tests performed to assess inhibition of protein denaturation, lipoxygenase activity, and proteinase activity demonstrated that borage extracts have anti-inflammatory properties. In addition, the methanol extract of the herb dried in a convection oven showed the strongest inhibition of both collagenase and elastase activity, which is indicative of anti-ageing properties. The results show that the borage extracts are a source of valuable bioactive compounds with beneficial properties in the context of skin cell protection.
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Mitich, Larry W. "White Man's Foot: Broadleaf Plantain." Weed Technology 1, no. 3 (1987): 250–51. http://dx.doi.org/10.1017/s0890037x00029638.

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Plantain, which weary toilers dig from their lawns, hoe from their gardens, or cultivate from their fields was brought to the United States to serve man. Originally considered a valuable medicinal herb and an edible green, it was grown in monastery gardens and was cultivated in botanic gardens. It still is raised as a crop for bird feed.
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Pol, Michal, Knut Schmidtke, and Sylwia Lewandowska. "Plantago lanceolata – An overview of its agronomically and healing valuable features." Open Agriculture 6, no. 1 (2021): 479–88. http://dx.doi.org/10.1515/opag-2021-0035.

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Abstract This article gives an overview of the widely distributed herb ribwort plantain (Plantago lanceolata). Currently, this plant is mostly grown in grasslands, rarely in arable land, and its secondary metabolites are used in medicine. Studies cited in the article indicate its very rapid growth and deep rooting in the soil, which results in high drought tolerance and uptake of valuable nutrients from deep soil layers. An intensive symbiosis with various mycorrhizal fungi is characteristic of plantain for a high capacity for nutrient and water appropriation. It is also characterized by different contents of iridoid glycosides like aucubin and catalpol in shoots and roots of different varieties. The use of P. lanceolata is discussed on permanent and non-permanent grasslands where agriculturally specific varieties have been developed for grazing animals showing positive health effects in them. Information is provided on the cultivation of ribwort plantain, including studies on sowing and fertilization, the yield and infestation of the plant with pathogens, and the occurrence of iridoid glycosides in the plant. In addition, information is included on pests that threaten the plant’s cultivation.
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DIMA, Milica, Aurelia DIACONU, Florentina NETCU, Cornel NETCU, and Emilia CONSTANTINESCU. "PRELIMINARY RESULTS REGARDING THE BEHAVIOR OF THE CASSIA ANGUSTIFOLIA VAHL. SPECIES ON THE SANDY SOILS OF THE SOUTH OF OLTENIA." "Annals of the University of Craiova - Agriculture Montanology Cadastre Series " 54, no. 1 (2024): 100–106. https://doi.org/10.52846/aamc.v54i1.1543.

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The research carried out had as its objective the introduction of some valuable medicinal and aromatic plant species into cultivation on sandy soils and aimed at enriching the collection of medicinal and aromatic plants existing at the Research Development Station Plant Culture Sands Dăbuleni .The behavior of the Cassia angustifolia Vahl. (senna) species on sandy soils was monitored in 2024 within the framework of Project 1.2.2,, Diversification of the assortment of medicinal, aromatic and Jerusalem artichoke plant species cultivated on sandy soils,, funded by Ministry of Agriculture and Rural Development.Under irrigation conditions, at Research Development Station Plant Culture Sands Dăbuleni, the senna crop recorded an average production of green herb of 12640 kg/ha and of dry herb of 2429 kg/ha.
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Pang, Han-Qing, Ding-Qiao Xu, Yu-Ping Tang, et al. "Comparatively Evaluating the Role of Herb Pairs Containing Angelicae Sinensis Radix in Xin-Sheng-Hua Granule by Withdrawal Analysis." Evidence-Based Complementary and Alternative Medicine 2020 (September 22, 2020): 1–13. http://dx.doi.org/10.1155/2020/9456350.

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The present study aims to investigate the roles of herb pairs containing Angelicae Sinensis Radix (Danggui) in Xin-Sheng-Hua Granule (XSHG) on hemolytic and aplastic anemia (HAA) mice. HAA model mice were induced by acetyl phenylhydrazine and cyclophosphamide; then the samples of XSHG and its decomposed recipes (DY, DC, DT, DH, DJ, and DZ) were orally administrated to these mice. Indicators of peripheral blood routine, organ index, and ATPase activities were tested. Moreover, the main effective components in these samples were also analyzed by UHPLC-TQ-MS/MS. Clear separation between the control and model groups from score plot of principal component analysis (PCA) was easily seen, indicating that HAA model was successfully conducted. Afterwards, relative distance calculation method between dose groups and control group from PCA score plot was adopted to evaluate the integrated effects of hematinic function of different samples. And the orders of hematinic effects were as follows: XHSG &gt; DJ &gt; DT &gt; DZ &gt; DH &gt; DC &gt; DY. Further analysis of these samples by UHPLC-TQ-MS/MS revealed that XSHG underwent complicated changes when herb pairs containing Danggui were excluded from XSHG, respectively. Compared with XSHG, the vast majority of active compounds in sample DY (formula minus herb pair Danggui-Yimucao) decreased significantly, which could partly explain why herb pair Danggui-Yimucao made great contribution to XSHG. These findings showed that withdrawal analysis method is a valuable tool to analyze the impacts of herb pairs containing Danggui on XSHG, which could lay foundation to reveal the compatibility rules of this formula.
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Khan, Aman, Prof Rajkumari Lodhi, and Dr Satish Nayak. "A Review on “A study of Anti Cancer Herb Vinca Rosea”." International Journal of Research and Scientific Innovation XII, no. IV (2025): 1372–82. https://doi.org/10.51244/ijrsi.2025.12040154.

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Vinca rosea, also called Catharanthus roseus or Madagascar periwinkle, is a widely recognized medicinal plant extensively researched for its strong anti-cancer properties. This review provides an in-depth look at the plant’s phytochemical composition, pharmacological effects, and therapeutic potential, with a particular focus on its role in cancer treatment. Vinca rosea is a valuable source of bioactive alkaloids, such as vincristine and vinblastine, which have been developed into effective chemotherapy drugs used to treat a variety of cancers, including leukemia, lymphoma, breast cancer, and lung cancer. These compounds primarily work by disrupting microtubule dynamics, which inhibits cell division and induces apoptosis in cancer cells. In addition to its clinical relevance, the review also examines the biological mechanisms behind its anti-cancer effects, current drug formulations and their pharmaceutical applications, toxicity levels, and challenges in drug development. Moreover, it discusses efforts to conserve the plant and biotechnological methods aimed at improving the sustainable production of these valuable alkaloids. By summarizing existing knowledge and highlighting research gaps, the paper emphasizes the importance of Vinca rosea in natural product-based cancer therapies and advocates for further exploration of its clinical potential and bioengineering applications.
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Datta, Kunal, Soubhik Bhattacharyya, and Dhrubajyoti Sarkar. "Major biochemical constituents of Premna integrifolia extract: A Review of chemical analysis." Research Journal of Biotechnology 19, no. 6 (2024): 137–48. http://dx.doi.org/10.25303/1906rjbt01370148.

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Premna integrifolia (Ganimari) is a precise widespread medicinal herb developed mainly in Sri Lanka and different regions of India. The plant grows wild in coastal districts of Andhra Pradesh, Orissa, West Bengal, Tamil Nadu and Kerala in India. Premna integrifolia, a valuable herb in Ayurveda, has many health advantages including analgesic, anti-inflammatory, antibacterial, antiarthritic, antioxidant, anti-ulcer, antidiabetic, CNS stimulant, hepatoprotective, cardiac stimulant, hypolipidemic and neurodegenerative disease-fighting properties. This review discusses the challenges and analytical approaches for determining the chemical components of Premna integrifolia, both quantitatively and qualitatively. This review also provides a thorough analysis of the methods used to accurately characterize the chemical profile of Premna integrifolia extract. The effectiveness of analytical methods like chromatography, UV-spectroscopy and mass spectrometry in identifying and quantifying bioactive constituents is being investigated.
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Joshee*, Nirmal, Bipul K. Biswas, and Anand K. Yadav. "Somatic Embryogenesis in Centella asiatica, a Valuable Medicinal Plant." HortScience 39, no. 4 (2004): 859C—859. http://dx.doi.org/10.21273/hortsci.39.4.859c.

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Centella asiatica L. (Apiaceae family), also called `Indian Pennywort,' is a prostrate, faintly aromatic, and stoloniferous perennial herb with long petiolated leaves. In the Ayurvedic medicine, it is reputed as a nervine tonic along with antibacterial, antifeedant, antileprotic and wound healing properties. Centella contains glycosides, indocentelloside, brahmoside, and asiaticoside. Its leaves are rich in carotenoids and vitamins B and C. In vitro culture techniques which offer a viable tool for mass propagation of plants have recently become increasingly popular for conservation of rare, endangered and threatened medicinal plants germplasm. Centella tissue culture has been reported to experience high incidences of microbial contamination which drastically reduces survival of explants. Thus, the main purpose of this study was to develop an efficient micropropagation technique for Centella asiatica to reduce explant contamination and rapidly disseminate superior clones for research and production. Here we present induction and further development of somatic embryos, using Centella stolons as explants. Somatic embryos were induced in response to 2,4-D shock on MS medium. Initially, somatic embryos appeared as highly nodular callus and eventually developed into somatic embryos that exhibited globular, heart shaped and cotyledonary stages. After auxin shock, cultures were regularly transferred to MS basal medium where somatic embryos completed various developmental stages and then germinated to give rise to new plantlets. In this presentation, we will demonstrate complete protocols for the successful sterilization of Centella explants prepared from plants that had abundance of fungal and bacterial contamination.
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Rosli, Khairul Azree, Azizah Misran, Latifah Saiful Yazan, and Puteri Edaroyati Megat Wahab. "Light-NPK Synergy Increases Biomass, Photosynthetic Pigment and Nitrogen Content in Agastache rugosa (Fisch. & C.A.Mey.) Kuntze." Journal of Tropical Plant Physiology 16, no. 2 (2024): 26. https://doi.org/10.56999/jtpp.2024.16.2.38.

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Agastache rugosa (Fisch. &amp; C.A.Mey.) is a medicinal herb native to subtropical and temperate climates which is highly valued for its essential oils and phytochemicals in the pharmaceutical, cosmetic, and food industries. This study examined the adaptive strategies of A. rugosa in response to varying light and NPK levels. The treatments were four NPK levels which were low (NPK1, 40 mg kg-1), moderate (NPK2, 80 mg kg-1), high (NPK3, 120 mg kg-1) and very high (NPK4, 160 mg kg-1) nested under two light levels namely high-light (HL, 0% shade) and low-light (LL, 50% shade). We uncovered a resource allocation mechanism that optimises growth and photosynthetic efficiency through a multidimensional analysis involving biomass, photosynthetic pigment, and nitrogen contents. High-light promoted greater biomass and pigment content across NPK treatments, with the most pronounced effects under low NPK levels, indicating enhanced nitrogen use efficiency. This suggested that strategic management of light levels could compensate for nutrient deficiencies in this valuable herb. High-light increased leaf nitrogen content in a non-linear way, implying shifts in resource allocation, which are crucial for optimising fertilisation. Principal component analysis exhibited distinct clustering patterns, highlighting the dominant effect of light on overall physiology, with NPK levels introducing a secondary gradient of variation. Our results demonstrated the complex interplay between light and NPK availability in shaping plant responses, challenging simplistic notions of productivity and proving the importance of considering multiple environmental factors in tandem. These insights advance our understanding of plant adaptation to environmental changes and offer valuable guidance for optimising cultivation practices in medicinal herb production.
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Wu, Peng, Wei Sun, Hucun Wang, Luhai Zhang, and Petru A. Simionescu. "Design and Testing of an Inter-Toothed, Self-Propelled Digger for Deep-Rhizome Chinese Herbal Medicines." Agronomy 14, no. 9 (2024): 2024. http://dx.doi.org/10.3390/agronomy14092024.

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To address the challenges of digging deep-rhizome Chinese herbal medicines in northwest China’s hilly terrain, including difficulty, incompleteness, and herb damage, a specialized self-propelled digger with interlocking teeth has been developed. Designed for complex topography, small fields, and resistant soil, this digger provides an efficient and precise alternative to traditional methods. The prototype features in-place reverse differential steering, 360-degree digging capability, and minimized root and soil damage to promote future planting. Key components, including the digging mechanism, vibratory system, crawler chassis, hydraulic transmission system, and worm gear rotary hydraulic reducer, were analyzed and optimized through theoretical, graphical, and simulation studies using RecurDyn. Field tests demonstrated the digger’s effectiveness, achieving depths exceeding 600 mm with minimal herb damage and loss. The digger successfully navigated steep slopes and operated within noise regulations, surpassing industry standards, with less than 1.4% herb damage and a loss rate under 3%. The digger was capable of ascending gradients over 20° with driver noise levels below 92 dB. This innovative solution offers a valuable reference for developing specialized diggers for harvesting traditional Chinese medicinal materials in challenging conditions.
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Fornal-Pieniak, Beata, and Agnieszka Mandziuk. "Comparison of vascular plants in herb layers of ecotones in urban and non-urban forests in Brzesko city (Polish Carpathian foreland)." Folia Forestalia Polonica 64, no. 3 (2022): 156–60. http://dx.doi.org/10.2478/ffp-2022-0015.

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Abstract Nowadays, human influence is more noticeable in urban and non-urban ecosystems, which, in turn, leads to the transformation of valuable natural resources. This article presents a study on the diversity of species composition of the vascular herb layer species of ecotones in selected urban forests of the city of Brzesko and in forests outside the city. All forests represented the association of oak–hornbeam plant. The results showed that there are inconsistent and consistent vascular plant species with the Tilio-Carpinetum habitat in urban and non-urban forests. Plant species were significantly (c2 test, p &lt; 0.05) found more frequently in the herb layer of non-urban forests than in urban forests. This proves, among other things, that the influence of anthropogenic activity is more on these objects than in forests outside the city.
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Ding, Ding, and Chenguang Yang. "Experience of Treating Malignant Tumor with Large Dose of Radix Rehmanniae Praeparata." Journal of Contemporary Medical Practice 6, no. 6 (2024): 174–78. http://dx.doi.org/10.53469/jcmp.2024.06(06).31.

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With more than 30 years of clinical experience, Professor Yang Chenguang is adept at using ancient classical prescriptions as well as high-quality prescriptions inherited by later generations of physicians to treat tumor-related diseases. Rehmannia rehmannia often becomes an indispensable clinical herb because of its efficacy and pharmacological effects, and its importance is self-evident, which is closely related to its main effect of "benefiting the kidney and filling essence". The purpose of this article is to share Professor Yang Chenguang's valuable experience in the clinical use of high-dose Rehmannia in the treatment of tumors and their complications, and to provide valuable reference and enlightenment for clinicians.
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Menon, Sudeep, Pooja Lavagale, Shyam Maru, Kashinath Bari, and Ashutosh Dasmohapatra. "An Ayurvedic Drug Review of Yashtimadhu (Glycyrrhiza glabra L.)." Journal of Neonatal Surgery 14, no. 18S (2025): 742–46. https://doi.org/10.63682/jns.v14i18s.5253.

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Yashtimadhu, scientifically known as Glycyrrhiza glabra L., is a revered herb in Ayurveda, recognized for its diverse therapeutic properties. This paper presents a comprehensive review of Yashtimadhu, exploring its classical Ayurvedic attributes, chemical composition, pharmacological actions, traditional uses, clinical applications, and safety considerations. Through a synthesis of traditional Ayurvedic knowledge and contemporary scientific research, this review aims to provide a holistic understanding of Yashtimadhu's potential as a valuable medicinal agent.
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Spanakis, Marios, Eleftheria Tzamali, Georgios Tzedakis, et al. "Artificial Intelligence Models and Tools for the Assessment of Drug–Herb Interactions." Pharmaceuticals 18, no. 3 (2025): 282. https://doi.org/10.3390/ph18030282.

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Artificial intelligence (AI) has emerged as a powerful tool in medical sciences that is revolutionizing various fields of drug research. AI algorithms can analyze large-scale biological data and identify molecular targets and pathways advancing pharmacological knowledge. An especially promising area is the assessment of drug interactions. The AI analysis of large datasets, such as drugs’ chemical structure, pharmacological properties, molecular pathways, and known interaction patterns, can provide mechanistic insights and identify potential associations by integrating all this complex information and returning potential risks associated with these interactions. In this context, an area where AI may prove valuable is in the assessment of the underlying mechanisms of drug interactions with natural products (i.e., herbs) that are used as dietary supplements. These products pose a challenging problem since they are complex mixtures of constituents with diverse and limited information regarding their pharmacological properties, especially their pharmacokinetic data. As the use of herbal products and supplements continues to grow, it becomes increasingly important to understand the potential interactions between them and conventional drugs and the associated adverse drug reactions. This review will discuss AI approaches and how they can be exploited in providing valuable mechanistic insights regarding the prediction of interactions between drugs and herbs, and their potential exploitation in experimental validation or clinical utilization.
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Jadhav, Dinesh. "Zea mays L. (Poaceae) – An Ethnomedicinal Plant Used in the Treatment of Kidney Stone by Native Folklore of Ratlam District (Madhya Pradesh)." Journal of Non Timber Forest Products 23, no. 4 (2016): 233–34. http://dx.doi.org/10.54207/bsmps2000-2016-t171ap.

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Corn silk (Stigma maydis) is an important herb used traditionally by the native Indians to treat many diseases. It is also used as traditional medicine in many parts of the world such as China, Turkey, United States and France. In present study it has been found to be very effective for the treatment of kidney stone. This valuable ethnomedicinal plant is interestingly used by the inhabitants of Ratlam district (M.P.) to cure their kidney stone.
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Mohapatra, Priyanka, Asit Ray, I. Sriram Sandeep, Reena Parida, and Sujata Mohanty. "Genetic and biochemical stability of in vitro raised and conventionally propagated Centella asiatica - A valuable medicinal herb." South African Journal of Botany 140 (August 2021): 444–53. http://dx.doi.org/10.1016/j.sajb.2021.01.004.

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Dangi, Subas, and Niranjan Parajuli. "Phytochemical analysis, antioxidant and antibacterial activities of methanolic rhizome extract of Bergenia pacumbis: A valuable medicinal herb." BIBECHANA 19, no. 1-2 (2022): 14–26. http://dx.doi.org/10.3126/bibechana.v19i1-2.45963.

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Bergenia pacumbis, a perennial herb of the Saxifragaceae family, usually referred to as ‘Pashanbheda’ is geographically distributed within the temperate Himalaya including Nepal. The purpose of this study was to evaluate the phytochemical analysis as well as in vitro antioxidant and antibacterial activities of methanolic rhizome extract of B. pacumbis. The rhizome of B. pacumbis was extracted in methanol using the Soxhlet apparatus and then the extract was concentrated. The rhizome extract was tested for phytochemicals using the standard protocol. The in vitro antioxidant activity of the extract was evaluated using the 2, 2- diphenyl-1-picrylhydrazyl free radical scavenging assay. The 50 % inhibitory concentration (IC50) values of ascorbic acid and B. pacumbis were found to be 11.91 ± 0.03 μg/mL and 11.99 ± 0.05 μg/mL respectively that indicate B. pacumbis is a good source of antioxidant agents. The extract was further tested for antibacterial activity through the agar well diffusion method and found to be effective against Staphylococcus aureus (16 mm) and Klebsiella pneumoniae (12 mm). The present study validates the traditional use of B. pacumbis. BIBECHANA 19 (2022) 14-26
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Singh, Mithilesh, Neha Pandey, Vasudha Agnihotri, K. K. Singh, and Anita Pandey. "Antioxidant, antimicrobial activity and bioactive compounds of Bergenia ciliata Sternb.: A valuable medicinal herb of Sikkim Himalaya." Journal of Traditional and Complementary Medicine 7, no. 2 (2017): 152–57. http://dx.doi.org/10.1016/j.jtcme.2016.04.002.

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Swarna, J., and R. Ravindhran. "In vitro propagation and assessment of genetic integrity of Talinum triangulare (Jacq.) Willd: a valuable medicinal herb." Acta Physiologiae Plantarum 34, no. 5 (2012): 1987–96. http://dx.doi.org/10.1007/s11738-012-0999-6.

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48

Verma, Prawal Pratap Singh, Dipender Kumar, Sushmita Rawat, B. Agri, Amit Kumar, and R. C. Padalia. "A study on nutrient optimization for enhanced geranium oil yield in the lower altitude zones of Uttarakhand, India." Journal of Applied Horticulture 25, no. 03 (2023): 303–7. http://dx.doi.org/10.37855/jah.2023.v25i03.54.

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This study, carried out at CSIR-Central Institute of Medicinal and Aromatic Plant Research Centre Purara, Bageshwar (Uttarakhand), investigated the growth and productivity of geranium crops under different NPK doses in the lower hills of Uttarakhand. Nine different NPK treatments, varying from 60:40:20 to 220:200:180 kg ha-1, were applied using a Randomised Block Design. Examined factors related to plant growth and yield, included plant height, diameter, stem count, leaf count, fresh shoot biomass per gramme of plant, and fresh herb yield per hectare. The 180:160:140 NPK level produced the highest fresh herb yield of 327.29 q ha-1, which corresponded to the highest oil yield of 163.65 kg ha-1. This study provides valuable insights into optimising NPK formulations to improve geranium crop yields, which is essential for increasing agricultural productivity in the Himalayan hills of Uttarakhand.
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Li, Wen-Lan, Jing-Xin Ding, Bing-Mei Liu, et al. "Phytochemical screening and estrogenic activity of total glycosides of Cistanche deserticola." Open Chemistry 17, no. 1 (2019): 279–87. http://dx.doi.org/10.1515/chem-2019-0035.

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AbstractOver the decades, there have been continuous efforts to enhance the quality of human life. Postmenopausal syndrome is a serious concern for the wellbeing of a woman's health. Hormonal therapy is currently the mainstay of treatment for this condition. However, this therapy could lead to estrogen abuse, leading to adverse reactions and side effects. As a result, hormonal therapy has been unsuccessful in ameliorating postmenopausal syndrome. Cistanche deserticola is a classical tonic herb in traditional Chinese medicine. It exhibits significant estrogenic activity. The main active compounds of this herb are glycosides. In a previous experiment, three important factors contributing to the total glycoside yield, acteoside yield, and estrogenic activity were identified, namely, eluent concentration, pH, and eluent volume. In this experiment, an optimal purification process was determined using a central composite design-response surface methodology to obtain glycosides from this herb. An eluent (ethanol) concentration of 85% and volume of 25 BV at a pH of 11 was found to be optimal. Twenty-one active compounds were identified by a high-performance liquid chromatography/ quadrupole time-of-flight mass spectrometry assay. This study provides valuable insights for further in-depth research evaluating the estrogenic activities of total glycosides of Cistanche deserticola.
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Gao, Jiayu, Xiao Yang, and Weiping Yin. "From Traditional Usage to Pharmacological Evidence: A Systematic Mini-Review of Spina Gleditsiae." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/3898957.

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Spina Gleditsiae is an important herb with various medicinal properties in traditional and folk medicinal systems of East Asian countries. In China through the centuries, it has been traditionally used as a source of drugs for anticancer, detoxication, detumescence, apocenosis, and antiparasites effects. Recently, an increasing number of studies have been reported regarding its chemical constituents and pharmacological activities. To further evidence the traditional use, phytochemicals, and pharmacological mechanisms of this herb, a systematic literature review was performed herein for Spina Gleditsiae. The review approach consisted of searching several web-based scientific databases including PubMed, Web of Science, and Elsevier using the keywords “Spina Gleditsiae”, “Zao Jiao Ci”, and “Gleditsia sinensis”. Based on the proposed criteria, 17 articles were evaluated in detail. According to the reviewed data, it is quite evident that Spina Gleditsiae contains a number of bioactive phytochemical components, which account for variety medicinal values including anticancer, anti-inflammatory, antiatherogenic, antimicrobial, antiallergic, and antivirus activities. The phytochemical and pharmacological studies reviewed herein strongly underpin a fundamental understanding of herbal Spina Gleditsiae and support its ongoing clinical uses in China. The further phytochemical evaluation, safety verification, and clinical trials are expected to progress Spina Gleditsiae-based development to finally transform the traditional TCM herb Spina Gleditsiae to the valuable authorized drug.
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