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Dissertations / Theses on the topic 'Variable number of tandem repeats'

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Published: 4 June 2021

Last updated: 19 February 2022

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1

SaidQasem, Osama. "Temporal and spatial explorations of Clostridium difficile variable number tandem repeats." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=211224.

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Clostridium difficile infection (CDI) has recently emerged as a major health problem. An understanding of the micro-epidemiology of the infection is decisive for the design and implementation of control polices. Presently, typing using PCR ribotyping (RT), Multi-locus Sequence Typing (MLST) and Multi-locus Variable Number Tandem Repeat Analysis (MLVA) can be used to investigate recent transmission events of C. difficile. In the case of MLVA, different criteria have been used to classify strains and this reflects inconsistencies in the contemporary knowledge of change in MLVA polymorphisms. In

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2

Manca, Maurizio. "Role of Variable Number Tandem Repeats (VNTRs) on gene expression in the CNS." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3007520/.

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It is now known that at least 80% of the human genome is composed of non-coding DNA which has a biochemical activity and is involved in a wide range of activities and mechanisms. Among these, epigenetic modifications, cis-trans gene expression regulation, transcription factor binding sequences, are the most studied. Non-coding DNA is often characterised by a polymorphic and repetitive nature and it is composed of a high density of GC nucleotides. These polymorphic and repetitive regions within the population may represent either protective elements or risk factors, based on population studies

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3

Kunorozva, Lovemore. "PERIOD3 variable number tandem repeat genotype associations with performance, injury, illness and re-entrainment." Doctoral thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22812.

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Background: Circadian rhythms are internally driven biological variations that fluctuate with a period of approximately 24 hours, even in the absence of external environmental time cues. These rhythms enable organisms to synchronise their internal clock time with external environmental time. This ensures appropriate timing of biological and metabolic processes, and allows anticipation of daily changes in the environment. Circadian rhythms also play an important role in sports in terms of optimising performance time-of-day and aiding adjustment to global time zone changes. Thus, performance, wh

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4

Schlaphoff, Theresa Elizabeth-Anne. "A study to evaluate variable number of tandem repeat DNA polymorphisms in disputed paternity testing." Thesis, Cape Technikon, 1993. http://hdl.handle.net/20.500.11838/1465.

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Thesis (MDip (Medical Technology))--Cape Technikon, 1993<br>The use of genetic marker testing to resolve cases of disputed paternity, is well established. The number and range of systems used depends on the expertise of the laboratory, and for this reason various laboratories offer different systems. Standard testing includes tests in the following genetic marker systems: human leukocyte antigen (tissue) typing; red cell blood groups; and red cell enzyme and serum protein testing. The Provincial Laboratory for Tissue Immunology currently offers a range of 16 genetic marker systems cap

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5

Ng, Sau-wah, and 吳秀華. "Population genetics study on the variable number of Tandem repeats (VNTR) loci of a Han Chinese population in Hong Kong and itsapplication in human identity." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31224994.

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6

Weipert, Christine [Verfasser]. "Die Heterozygotie des Längenpolymorphismus "variable number of tandem repeats" des thrombozytären Glykoproteins Iba alpha als Risikofaktor für koronare Herzkrankheit und Myokardinfarkt in Niedrigrisikogruppen / Christine Weipert." Gießen : Universitätsbibliothek, 2014. http://d-nb.info/1068591617/34.

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7

Box, Matthew. "Multiple-locus variable-number tandem-repeat analysis (MLVA) for clonal characterization of methicillin resistant Staphylococcus aureus strains." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. https://www.mhsl.uab.edu/dt/2008r/box.pdf.

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8

Radtke, Andreas. "Molecular Methods for Typing of Streptococcus agalactiae with Special Emphasis on the Development and Validation of a Multi-Locus Variable Number of Tandem Repeats Assay (MLVA)." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for laboratoriemedisin, barne- og kvinnesykdommer, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-17135.

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Molekylære metoder for typing av Streptococcus agalactiae med særlig vektlegging av utvikling og validering av et multi-locus variable number of tandem repeats assay (MLVA) Sammendraget: Streptococcus agalactiae eller gruppe B streptokokker (GBS) forårsaker livsfarlige infeksjoner hos nyfødte, gravide eller voksne med kroniske sykdommer. Den forårsaker også jurbetennelse i storfe. Typing av GBS gir innblikk i bakteriens epidemiologi og dens fylogenetiske slektskap. Ulike deler av bakteriene kan være mål for typingsmetoder. Eldre immunologiske metoder fokuserer ofte på overflateegenskaper som p

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9

Ng, Sau-wah. "Population genetics study on the variable number of Tandem repeats (VNTR) loci of a Han Chinese population in Hong Kong and its application in human identity." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2292582X.

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10

Fujita, Kohei. "Association between polyclonal and mixed mycobacterial Mycobacterium avium complex infection and environmental exposure." Kyoto University, 2014. http://hdl.handle.net/2433/188673.

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11

Razzaghian, Hamid Reza. "Post-zygotic Genetic Variation in Health and Disease." Doctoral thesis, Uppsala universitet, Medicinsk genetik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-196217.

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Post-zygotic genetic variation has previously been shown in healthy individuals and linked to various disorders. The definition of post-zygotic or somatic variation is the existence of genetically distinct populations of cells in a subject derived from a single zygote. Structural changes in the human genome are a major type of inter-individual genetic variation and copy number variation (CNV), involving changes in the copy number of genes, are one of the best studied category of structural genetic changes. In paper I we reported a pair of healthy female monozygotic (MZ) twins discordant for an

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12

Constien, Christine Verfasser], and Alexander [Akademischer Betreuer] [Mellmann. "Entwicklung und Evaluierung der „Multilocus Variable Number Tandem Repeat Sequenztypisierung (MLVST)“ zur Typisierung von Enterococcus faecium / Christine Constien ; Betreuer: Alexander Mellmann." Münster : Universitäts- und Landesbibliothek Münster, 2017. http://d-nb.info/1142527972/34.

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13

Constien, Christine [Verfasser], and Alexander [Akademischer Betreuer] Mellmann. "Entwicklung und Evaluierung der „Multilocus Variable Number Tandem Repeat Sequenztypisierung (MLVST)“ zur Typisierung von Enterococcus faecium / Christine Constien ; Betreuer: Alexander Mellmann." Münster : Universitäts- und Landesbibliothek Münster, 2017. http://d-nb.info/1142527972/34.

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14

Varela, Filipa Alexandra Pereira Rosa. "Tipificação de Mycoplasma mycoides subsp. mycoides SC e detecção da sua aderência a células epiteliais pulmonares." Master's thesis, Faculdade de Ciências e Tecnologia, 2010. http://hdl.handle.net/10362/5092.

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Dissertação apresentada para a obtenção do Grau de Mestre em Genética Molecular e Biomedicina, pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia<br>A Peripneumonia Contagiosa Bovina (PPCB) é uma doença respiratória infecciosa, de grande relevo no âmbito da produção de gado bovino, causada pela bactéria Mycoplasma mycoides subsp. mycoides SC (MmmSC). Actualmente, a PPCB permanece endémica apenas em África, sendo aí responsável por perdas incontornáveis no sector pecuário. O último surto de PPCB detectado na Europa ocorreu em Portugal em 1999 mas, devido à sua natureza insidio

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15

Lebeurre, Jérémie. "Analyse comparative de génomes complets de souches pathogènes et de portage de Staphylococcus lugdunensis et caractérisation du système de sécrétion Ess/type VII." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMR081/document.

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La première partie de nos travaux a consisté au séquençage de génomes complets de trois souches pathogènes et de trois souches de portage de Staphylococcus lugdunensis pour les comparer aux 15 génomes complets disponibles sur NCBI. Aucun déterminant génétique associé au contexte de virulence ou de portage de S. lugdunensis n’a été identifié. Cependant, nous avons mis en évidence la présence d’éléments génétiques mobiles et des variations dépendantes des complexes clonaux,définis par MultiLocus Sequence Typing, au sein de loci potentiellement associés à la virulence. Des variations ont été obse

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16

Ceccucci-Völker, Alexander Richard Karl [Verfasser]. "Einfluss des 40 Basenpaar variable number of tandem repeat des humanen Dopamintransporters auf die Entwicklung extrapyramidal-motorischer Arzneimittelwirkungen bei schizophrenen Patienten unter Antipsychotikatherapie / Alexander Richard Karl Ceccucci-Völker." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2009. http://d-nb.info/1023747758/34.

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17

Dahyot, Sandrine. "Contribution à la compréhension des mécanismes moléculaires impliqués dans la virulence de Staphylococcus lugdunensis." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR046/document.

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Nos travaux ont cherché à mieux comprendre les mécanismes à l’origine de la virulence de Staphylococcus lugdunensis, espèce au pouvoir pathogène proche de celui de Staphylococcus aureus. Nous avons procédé à la première caractérisation fonctionnelle chez cette espèce d’un système à deux composants, LytSR. Ce système s’est révélé impliqué dans le contrôle de processus métaboliques majeurs et dans la virulence. Il est en effet impliqué dans la formation de biofilm, probablement en lien avec le contrôle exercé sur la mort cellulaire. LytSR est de plus impliqué dans la pathogenèse des infections à

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18

Feuerschuette, Otto Henrique May. "Diversidade genética e características fenotípicas do estreptococo do grupo B do trato anogenital de gestantes." reponame:Repositório Institucional da UNISUL, 2018. http://www.riuni.unisul.br/handle/12345/4823.

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Introduction: Colonization of the anogenital tract of pregnant women by Group B Streptococcus (GBS) is the main risk factor for early-onset neonatal sepsis. Identification of maternal colonization allows antimicrobial prophylaxis and prevention of vertical transmission. Objectives: To identify the genetic diversity and phenotypic characteristics of GBS using molecular biology techniques and culture in specific medium, and the epidemiological aspects of pregnant women colonized by this bacterium. Methods: It was performed a cross-sectional study, anogenital samples of 316 pregnant women were co

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19

Kam, Janice Lik Ming. "MUC1 synthetic peptide inhibition of ICAM-1 and MUC1 binding is dependent on the number of tandem repeats." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0026/MQ34381.pdf.

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20

Chang, Chia-Hung, and 張嘉宏. "Automatically Predicting Possible Loci of Variable Number of Tandem Repeats." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/03720752099789861973.

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碩士<br>國立臺灣大學<br>資訊工程學研究所<br>92<br>Variable number of tandem repeats (VNTR) stands for a tandem repeat which has variation in length and the number of repeated segments between individuals. VNTRs are useful as molecule markers in many applications, such as DNA fingerprinting, genetic disease analysis and molecular typing of prokaryotes. It costs a large amount of money and time to identify these special loci by using traditional biological experiments. Here we develop a novel tool, VNTR analyzer, to identify and analyze VNTR in genome sequence by comparing genomic sequences of different stra

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21

Marques, Isabel Maria. "Variable number of tandem repeat polymorphisms of man in Southern Africa." Thesis, 1992. http://hdl.handle.net/10539/22190.

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A thesis submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy<br>Two classes of hypervariable loci, VNTRs and (CA)n repeats, represent a rich source of highly polymorphic markers in the human genome. The main objective of this study was to assess their usefulness in elucidating the relationships between 17 southern African populations and to assess the feasibility of paternity testing using these hypervariable markers in the local context.<br>WHSLYP2017

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22

Rumore, Jillian. "Application and interpretation of multiple locus variable number tandem repeat analysis for Escherichia coli O157:H7 laboratory surveillance and outbreak response in Canada, 2008-2012." 2014. http://hdl.handle.net/1993/23863.

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To enhance outbreak investigations of Shiga toxin-producing Escherichia coli O157:H7, PulseNet Canada has recently applied Multiple Locus Variable Number Tandem Repeat Analysis (MLVA) as a supplemental subtyping tool in combination with the gold standard subtyping method Pulsed-field Gel Electrophoresis (PFGE) for enhanced resolution of isolates exhibiting indistinguishable/highly similar PFGE patterns. The objective was to assess the discriminatory power and level of specificity MLVA offers for outbreak detection and response. Results demonstrate that MLVA provides a statistically significa

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23

Yao, Chou-Hao, and 姚秋好. "A study of quantification of the copy number of short tandem repeats using ligation and bioluminescence method." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/b96hh4.

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碩士<br>國立臺北科技大學<br>生物科技研究所<br>99<br>Short tandem repeats (STRs) composing one to six nucleotides non-randomly distribute throughout the euchromatic genome. Their polymorphisms have been used as a diagnostic marker for cancer and several hereditary neurodegenerative disorders and analysis development of evolution and pedigrees. In this study, we used DNA ligation and bioluminescence to determine the copy number of the STR. The primer and the probes were ligated when they are complementary to the proper sites of the template containing short tandem repeats. The copy number of the STR is proportio

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