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Journal articles on the topic 'Variable number of tandem repeats'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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1

Kim, Song, Ha, et al. "Variable Number Tandem Repeats in the Mitochondrial DNA of Lentinula edodes." Genes 10, no. 7 (2019): 542. http://dx.doi.org/10.3390/genes10070542.

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Variable number tandem repeats (VNTRs) in mitochondrial DNA (mtDNA) of Lentinula edodes are of interest for their role in mtDNA variation and their application as genetic marker. Sequence analysis of three L. edodes mtDNAs revealed the presence of VNTRs of two categories. Type I VNTRs consist of two types of repeat units in a symmetric distribution, whereas Type II VNTRs contain tandemly arrayed repeats of 7- or 17-bp DNA sequences. The number of repeat units was variable depending on the mtDNA of different strains. Using the variations in VNTRs as a mitochondrial marker and the A mating type

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2

Huang, Ying, Xin Huang, Xuming Zhou, et al. "Immune activation by a multigene family of lectins with variable tandem repeats in oriental river prawn ( Macrobrachium nipponense )." Open Biology 10, no. 9 (2020): 200141. http://dx.doi.org/10.1098/rsob.200141.

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Genomic regions with repeated sequences are unstable and prone to rapid DNA diversification. However, the role of tandem repeats within the coding region is not fully characterized. Here, we have identified a new hypervariable C-type lectin gene family with different numbers of tandem repeats (Rlecs; R means repeat) in oriental river prawn ( Macrobrachium nipponense ) . Two types of repeat units (33 or 30 bp) are identified in the second exon, and the number of repeat units vary from 1 to 9. Rlecs can be classified into 15 types through phylogenetic analysis. The amino acid sequences in the sa

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3

Bakhtiari, Mehrdad, Sharona Shleizer-Burko, Melissa Gymrek, Vikas Bansal, and Vineet Bafna. "Targeted genotyping of variable number tandem repeats with adVNTR." Genome Research 28, no. 11 (2018): 1709–19. http://dx.doi.org/10.1101/gr.235119.118.

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4

Ghosh, Raikamal, G. Balakrish Nair, Li Tang, et al. "Epidemiological study ofVibrio choleraeusing variable number of tandem repeats." FEMS Microbiology Letters 288, no. 2 (2008): 196–201. http://dx.doi.org/10.1111/j.1574-6968.2008.01352.x.

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5

Danandeh, Mostafa, Seyed Reza Moadab, Mohammad Asgharzadeh, Naser Alizadeh, and Reza Ghotaslou. "Mycobacterium tuberculosis Diversity by Exact Tandem Repeats-Variable Number Tandem Repeat Method in Azerbaijan, Iran." Infectious Diseases in Clinical Practice 26, no. 2 (2018): 80–83. http://dx.doi.org/10.1097/ipc.0000000000000561.

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6

Subirana, Juan A., and Xavier Messeguer. "Tandem Repeats in Bacillus: Unique Features and Taxonomic Distribution." International Journal of Molecular Sciences 22, no. 10 (2021): 5373. http://dx.doi.org/10.3390/ijms22105373.

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Little is known about DNA tandem repeats across prokaryotes. We have recently described an enigmatic group of tandem repeats in bacterial genomes with a constant repeat size but variable sequence. These findings strongly suggest that tandem repeat size in some bacteria is under strong selective constraints. Here, we extend these studies and describe tandem repeats in a large set of Bacillus. Some species have very few repeats, while other species have a large number. Most tandem repeats have repeats with a constant size (either 52 or 20–21 nt), but a variable sequence. We characterize in detai

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Broza, Yoav Y., Yael Danin-Poleg, Larisa Lerner, Lea Valinsky, Meir Broza, and Yechezkel Kashi. "Epidemiologic Study ofVibrio vulnificusInfections by Using Variable Number Tandem Repeats." Emerging Infectious Diseases 15, no. 8 (2009): 1282–85. http://dx.doi.org/10.3201/eid1508.080839.

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8

Porrini, S. Costanzi, A. Sciarra, N. Sulli, M. Piane, R. Gualtieri, and G. Del Porto. "Variable Number of Tandem Repeats in Zygosity Diagnosis in Twins." Acta geneticae medicae et gemellologiae: twin research 39, no. 4 (1990): 473–77. http://dx.doi.org/10.1017/s000156600000369x.

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AbstractThe use of DNA restriction fragment length polymorphisms (RFLP) to analyze variable number of tandem repeat (VNTR) sequences dispersed in the human genome, has become a powerful tool for the study of population genetics due to the very substantial polymorphism involved. Because the markers usually employed for twin zygosity determination (such as sex combination, placentation, HLA typing, blood group antigens, etc) may not be uniformly informative, we propose the use of synthetic olygonucleotides, representing VNTR “core” sequences, for the determination of zygosity in twins.

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9

Monot, M., N. Honore, C. Baliere, et al. "Are Variable-Number Tandem Repeats Appropriate for Genotyping Mycobacterium leprae?" Journal of Clinical Microbiology 46, no. 7 (2008): 2291–97. http://dx.doi.org/10.1128/jcm.00239-08.

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10

Urbančič, Dunja, Alenka Šmid, Gabriele Stocco, Giuliana Decorti, Irena Mlinarič-Raščan, and Nataša Karas Kuželički. "Novel motif of variable number of tandem repeats in TPMT promoter region and evolutionary association of variable number of tandem repeats with TPMT*3 alleles." Pharmacogenomics 19, no. 17 (2018): 1311–22. http://dx.doi.org/10.2217/pgs-2018-0123.

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11

Coletta-Filho, Helvécio Della, Marco Aurélio Takita, Alessandra Alves de Souza, Carlos Ivan Aguilar-Vildoso, and Marcos Antonio Machado. "Differentiation of Strains of Xylella fastidiosa by a Variable Number of Tandem Repeat Analysis." Applied and Environmental Microbiology 67, no. 9 (2001): 4091–95. http://dx.doi.org/10.1128/aem.67.9.4091-4095.2001.

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ABSTRACT Short sequence repeats (SSRs) with a potential variable number of tandem repeat (VNTR) loci were identified in the genome of the citrus pathogen Xylella fastidiosa and used for typing studies. Although mono- and dinucleotide repeats were absent, we found several intermediate-length 7-, 8-, and 9-nucleotide repeats, which we examined for allelic polymorphisms using PCR. Five genuine VNTR loci were highly polymorphic within a set of 27 X. fastidiosa strains from different hosts. The highest average Nei's measure of genetic diversity (H) estimated for VNTR loci was 0.51, compared to 0.17

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12

Jung, Kyoung-Hwa, Sang-Hoon Kim, Seong-Joo Kim, Ji-Cheon Kim, and Young-Gyu Chai. "Strain-specific Detection of Bacillus Anthracis using Multiple-locus Variable-number Tandem Repeat Analysis." Journal of the Korea Institute of Military Science and Technology 14, no. 2 (2011): 305–12. http://dx.doi.org/10.9766/kimst.2011.14.2.305.

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13

Doran, G., N. DeLappe, J. O'Connor, D. Morris, M. Cormican, and B. Lindstedt. "P1859 Variable number of tandem repeats of S. typhimurium in Ireland." International Journal of Antimicrobial Agents 29 (March 2007): S532. http://dx.doi.org/10.1016/s0924-8579(07)71698-9.

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14

van Belkum, A., S. Scherer, W. van Leeuwen, D. Willemse, L. van Alphen, and H. Verbrugh. "Variable number of tandem repeats in clinical strains of Haemophilus influenzae." Infection and immunity 65, no. 12 (1997): 5017–27. http://dx.doi.org/10.1128/iai.65.12.5017-5027.1997.

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15

Liu, Shiguo, Jiajia Cui, Xinhua Zhang, et al. "Variable number tandem repeats in dopamine receptor D4 in Tourette's syndrome." Movement Disorders 29, no. 13 (2014): 1687–91. http://dx.doi.org/10.1002/mds.26027.

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16

Paquette, Jean, Nick Giannoukakis, Constantin Polychronakos, Petros Vafiadis, and Cheri Deal. "TheINS5′ Variable Number of Tandem Repeats Is Associated withIGF2Expression in Humans." Journal of Biological Chemistry 273, no. 23 (1998): 14158–64. http://dx.doi.org/10.1074/jbc.273.23.14158.

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17

Claisse, Olivier, and Aline Lonvaud-Funel. "Multiplex variable number of tandem repeats for Oenococcus oeni and applications." Food Microbiology 38 (April 2014): 80–86. http://dx.doi.org/10.1016/j.fm.2013.08.012.

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18

Marshall, Jack NG, Ana Illera Lopez, Abigail L. Pfaff, Sulev Koks, John P. Quinn, and Vivien J. Bubb. "Variable number tandem repeats – Their emerging role in sickness and health." Experimental Biology and Medicine 246, no. 12 (2021): 1368–76. http://dx.doi.org/10.1177/15353702211003511.

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Understanding the mechanisms regulating tissue specific and stimulus inducible regulation is at the heart of understanding human biology and how this translates to wellbeing, the ageing process, and disease progression. Polymorphic DNA variation is superimposed as an extra layer of complexity in such processes which underpin our individuality and are the focus of personalized medicine. This review focuses on the role and action of repetitive DNA, specifically variable number tandem repeats and SINE-VNTR- Alu domains, highlighting their role in modification of gene structure and gene expression

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19

Maeda-Mitani, Eriko, Koichi Murakami, Akira Oishi, Yoshiki Etoh, Nobuyuki Sera, and Shuji Fujimoto. "Typing Method for the QUB11a Locus ofMycobacterium tuberculosis: IS6110Insertions and Tandem Repeat Analysis." BioMed Research International 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/5216530.

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QUB11a is used as a locus for variable number of tandem repeats (VNTR) analysis ofMycobacterium tuberculosisBeijing lineage. However, amplification of QUB11a occasionally produces large fragments (>1,400 bp) that are not easily measured by capillary electrophoresis because of a lack of the typical stutter peak patterns that are used for counting repeat numbers. IS6110insertion may complicate VNTR analysis of large QUB11a fragments inM. tuberculosis. We established a method for determining both tandem repeat numbers and IS6110insertion in the QUB11a locus ofM. tuberculosisusing capillary ele

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20

Taylor, John S., and Felix Breden. "Slipped-Strand Mispairing at Noncontiguous Repeats in Poecilia reticulata: A Model for Minisatellite Birth." Genetics 155, no. 3 (2000): 1313–20. http://dx.doi.org/10.1093/genetics/155.3.1313.

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Abstract The standard slipped-strand mispairing (SSM) model for the formation of variable number tandem repeats (VNTRs) proposes that a few tandem repeats, produced by chance mutations, provide the “raw material” for VNTR expansion. However, this model is unlikely to explain the formation of VNTRs with long motifs (e.g., minisatellites), because the likelihood of a tandem repeat forming by chance decreases rapidly as the length of the repeat motif increases. Phylogenetic reconstruction of the birth of a mitochondrial (mt) DNA minisatellite in guppies suggests that VNTRs with long motifs can fo

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21

Tan, John C., Asako Tan, Lisa Checkley, Caroline M. Honsa, and Michael T. Ferdig. "Variable Numbers of Tandem Repeats in Plasmodium falciparum Genes." Journal of Molecular Evolution 71, no. 4 (2010): 268–78. http://dx.doi.org/10.1007/s00239-010-9381-8.

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22

., Rashid Ramazanzadeh, and Ruth McNerney . "Variable Number of Tandem Repeats (VNTR) and its Application in Bacterial Epidemiology." Pakistan Journal of Biological Sciences 10, no. 16 (2007): 2612–21. http://dx.doi.org/10.3923/pjbs.2007.2612.2621.

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23

Capurso, C., V. Solfrizzi, A. D'Introno, et al. "Interleukin 6 Variable Number of Tandem Repeats (VNTR) Gene Polymorphism in Centenarians." Annals of Human Genetics 71, no. 6 (2007): 843–48. http://dx.doi.org/10.1111/j.1469-1809.2007.00368.x.

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24

Smittipat, N., P. Billamas, M. Palittapongarnpim, et al. "Polymorphism of Variable-Number Tandem Repeats at Multiple Loci in Mycobacterium tuberculosis." Journal of Clinical Microbiology 43, no. 10 (2005): 5034–43. http://dx.doi.org/10.1128/jcm.43.10.5034-5043.2005.

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25

Mouton, L., and D. Ebert. "Variable-Number-of-Tandem-Repeats Analysis of Genetic Diversity in Pasteuria ramosa." Current Microbiology 56, no. 5 (2008): 447–52. http://dx.doi.org/10.1007/s00284-008-9104-1.

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26

Bustamante, A. V., A. M. Sanso, D. O. Segura, A. E. Parma, and P. M. A. Lucchesi. "Dynamic of Mutational Events in Variable Number Tandem Repeats ofEscherichia coliO157:H7." BioMed Research International 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/390354.

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VNTRs regions have been successfully used for bacterial subtyping; however, the hypervariability in VNTR loci is problematic when trying to predict the relationships among isolates. Since few studies have examined the mutation rate of these markers, our aim was to estimate mutation rates of VNTRs specific for verotoxigenicE. coliO157:H7. The knowledge of VNTR mutational rates and the factors affecting them would make MLVA more effective for epidemiological or microbial forensic investigations. For this purpose, we analyzed nine loci performing parallel, serial passage experiments (PSPEs) on 9

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27

van Gils, Carla H., Kathleen Conway, Yu Li, and Jack A. Taylor. "HRAS1 variable number of tandem repeats polymorphism and risk of bladder cancer." International Journal of Cancer 100, no. 4 (2002): 414–18. http://dx.doi.org/10.1002/ijc.10497.

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28

Cooley, Michael B., Diana Carychao, Kimberly Nguyen, Linda Whitehand, and Robert Mandrell. "Effects of Environmental Stress on Stability of Tandem Repeats in Escherichia coli O157:H7." Applied and Environmental Microbiology 76, no. 10 (2010): 3398–400. http://dx.doi.org/10.1128/aem.02373-09.

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ABSTRACT Multilocus variable-number tandem-repeat analysis (MLVA) is used for source tracking Escherichia coli O157:H7 in agricultural environments. Tandem repeats were stable after limited replication but changed after exposure to irradiation, elevated temperatures, and starvation conditions. The pO157 plasmid was frequently lost under these stress conditions. Environmental stresses may increase phylogenetic diversity as measured by MLVA.

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29

Zhu, Luchang, Randall J. Olsen, Nicola Horstmann, et al. "Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream ofrocAAlters Toxin Production and Enhances Virulence in Streptococcus pyogenes." Infection and Immunity 84, no. 7 (2016): 2086–93. http://dx.doi.org/10.1128/iai.00258-16.

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Variable-number tandem-repeat (VNTR) polymorphisms are ubiquitous in bacteria. However, only a small fraction of them has been functionally studied. Here, we report an intergenic VNTR polymorphism that confers an altered level of toxin production and increased virulence inStreptococcus pyogenes. The nature of the polymorphism is a one-unit deletion in a three-tandem-repeat locus upstream of therocAgene encoding a sensor kinase.S. pyogenesstrains with this type of polymorphism cause human infection and produce significantly larger amounts of the secreted cytotoxinsS. pyogenesNADase (SPN) and st

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30

NOLLET, Séverine, Nicolas MONIAUX, Jacques MAURY, et al. "Human mucin gene MUC4: organization of its 5′-region and polymorphism of its central tandem repeat array." Biochemical Journal 332, no. 3 (1998): 739–48. http://dx.doi.org/10.1042/bj3320739.

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In a previous study we isolated a partial cDNA with a tandem repeat of 48 bp, which allowed us to map a novel human mucin gene named MUC4to chromosome 3q29. Here we report the organization and sequence of the 5´-region and its junction with the tandem repeat array of MUC4. Analysis of three overlapping genomic clones allowed us to obtain a partial restriction map of MUC4 and to locate the complete 48 bp tandem repeat domain on a PstI/EcoRI genomic fragment that exhibits a very large variation in number of tandem repeats (7–19 kb). cDNA clonal extension allowed us to obtain the entire 5´ coding

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31

Simsek, S., P. M. M. Bleeker, C. E. van der Schoot та A. E. G. Kr von dem Borne. "Association of a Variable Number of Tandem Repeats (VNTR) in Glycoprotein Ibα and HPA-2 Alloantigens". Thrombosis and Haemostasis 72, № 05 (1994): 757–61. http://dx.doi.org/10.1055/s-0038-1648954.

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SummaryThe human platelet alloantigen HPA-2 (Koa/Kob) system is involved in two clinical syndromes, neonatal alloimmune thrombocytopenia and platelet transfusion refractoriness. Wb have previously described that the human platelet alloantigens HPA-2a(Kob) and HPA-2b(Koa), are caused by a Thrl45Met amino acid polymorphism in the N-terminal globular domain of the human platelet glycoprotein (GP) Ibα. In the present study the question was addressed as to whether a genetic association exists between this Thrl45Met polymorphism and the recently described variable number of tandem repeat (VNTR) poly

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32

Simmons, Warren L., Amy M. Denison, and Kevin Dybvig. "Resistance of Mycoplasma pulmonis to Complement Lysis Is Dependent on the Number of Vsa Tandem Repeats: Shield Hypothesis." Infection and Immunity 72, no. 12 (2004): 6846–51. http://dx.doi.org/10.1128/iai.72.12.6846-6851.2004.

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ABSTRACT The Vsa proteins are associated with the virulence of the murine respiratory pathogen Mycoplasma pulmonis. The antigens consist of a conserved N-terminal region that is combined with one of several different variable C-terminal regions comprised of tandem repeats. M. pulmonis strains that produce VsaA with about 40 tandem repeats do not adhere to polystyrene or erythrocytes and are highly resistant to complement killing. Strains that produce VsaA with three tandem repeats adhere strongly to polystyrene and erythrocytes and are highly susceptible to complement killing. We report here t

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33

Dreo, T., M. Ravnikar, J. E. Frey, T. H. M. Smits, and B. Duffy. "IN SILICO ANALYSIS OF VARIABLE NUMBER OF TANDEM REPEATS IN ERWINIA AMYLOVORA GENOME." Acta Horticulturae, no. 896 (May 2011): 115–18. http://dx.doi.org/10.17660/actahortic.2011.896.13.

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34

Chalmers, G., S. W. Martin, J. F. Prescott, and P. Boerlin. "Typing of Clostridium perfringens by multiple-locus variable number of tandem repeats analysis." Veterinary Microbiology 128, no. 1-2 (2008): 126–35. http://dx.doi.org/10.1016/j.vetmic.2007.09.018.

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35

Bougnères, Pierre. "Genotypic and Phenotypic Complexity at the Insulin Variable Number of Tandem Repeats Locus." Journal of Clinical Endocrinology & Metabolism 91, no. 11 (2006): 4246–49. http://dx.doi.org/10.1210/jc.2006-1728.

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36

Smittipat, N., and P. Palittapongarnpim. "Identification of possible loci of variable number of tandem repeats in Mycobacterium tuberculosis." Tubercle and Lung Disease 80, no. 2 (2000): 69–74. http://dx.doi.org/10.1054/tuld.2000.0236.

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37

Klevytska, A. M., L. B. Price, J. M. Schupp, P. L. Worsham, J. Wong, and P. Keim. "Identification and Characterization of Variable-Number Tandem Repeats in the Yersinia pestis Genome." Journal of Clinical Microbiology 39, no. 9 (2001): 3179–85. http://dx.doi.org/10.1128/jcm.39.9.3179-3185.2001.

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38

Lindstedt, Bjørn-Arne. "Multiple-locus variable number tandem repeats analysis for genetic fingerprinting of pathogenic bacteria." ELECTROPHORESIS 26, no. 13 (2005): 2567–82. http://dx.doi.org/10.1002/elps.200500096.

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39

Joob, Beuy, and Viroj Wiwanitkit. "Comment on “IL1-RN variable number of tandem repeats polymorphism with osteoarthritis risk”." Acta Orthopaedica et Traumatologica Turcica 54, no. 4 (2020): 472. http://dx.doi.org/10.5152/j.aott.2020.19191.

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40

Hopkins, K. L., C. Maguire, E. Best, E. Liebana, and E. J. Threlfall. "Stability of Multiple-Locus Variable-Number Tandem Repeats in Salmonella enterica Serovar Typhimurium." Journal of Clinical Microbiology 45, no. 9 (2007): 3058–61. http://dx.doi.org/10.1128/jcm.00715-07.

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41

Ramisse, V., P. Houssu, E. Hernandez, et al. "Variable Number of Tandem Repeats in Salmonella enterica subsp. enterica for Typing Purposes." Journal of Clinical Microbiology 42, no. 12 (2004): 5722–30. http://dx.doi.org/10.1128/jcm.42.12.5722-5730.2004.

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42

LUNT, DAVID H., LAWRENCE E. WHIPPLE, and BRADLEY C. HYMAN. "Mitochondrial DNA variable number tandem repeats (VNTRs): utility and problems in molecular ecology." Molecular Ecology 7, no. 11 (1998): 1441–55. http://dx.doi.org/10.1046/j.1365-294x.1998.00495.x.

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43

Yazdankhah, S. P., B. A. Lindstedt, and D. A. Caugant. "Use of Variable-Number Tandem Repeats To Examine Genetic Diversity of Neisseria meningitidis." Journal of Clinical Microbiology 43, no. 4 (2005): 1699–705. http://dx.doi.org/10.1128/jcm.43.4.1699-1705.2005.

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44

Course, Meredith M., Arvis Sulovari, Kathryn Gudsnuk, Evan E. Eichler, and Paul N. Valdmanis. "Characterizing nucleotide variation and expansion dynamics in human-specific variable number tandem repeats." Genome Research 31, no. 8 (2021): 1313–24. http://dx.doi.org/10.1101/gr.275560.121.

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45

Afshar-Kharghan, Vahid, Reyhan Diz-Küçükkaya, Erwin H. Ludwig, Ali J. Marian, and José A. López. "Human polymorphism of P-selectin glycoprotein ligand 1 attributable to variable numbers of tandem decameric repeats in the mucinlike region." Blood 97, no. 10 (2001): 3306–7. http://dx.doi.org/10.1182/blood.v97.10.3306.

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Abstract Platelet GP Ibα and leukocyte P-selectin glycoprotein ligand 1 (PSGL-1) are membrane mucins with a number of structural and functional similarities. It was investigated whether, like GP Ibα, PSGL-1 is affected by a variable number of tandem repeat polymorphism in its mucin-like region. By polymerase chain reaction amplification of the genomic region encoding the PSGL-1 repeats, 3 allelic variants were identified in the human population. The 3 alleles—A, B, and C—from largest to smallest, contained 16, 15, and 14 decameric repeats, respectively, with the B variant lacking repeat 2 and

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46

Eikenboom, Jeroen C. J., Pieter H. Reitsma, Pieter A. Velden, and Ernest Briët. "Instability of repeats of the von Willebrand factor gene variable number tandem repeat sequence in intron 40." British Journal of Haematology 84, no. 3 (1993): 533–35. http://dx.doi.org/10.1111/j.1365-2141.1993.tb03114.x.

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47

Mouton, Laurence, Guang Nong, James F. Preston, and Dieter Ebert. "Variable-Number Tandem Repeats as Molecular Markers for Biotypes of Pasteuria ramosa in Daphnia spp." Applied and Environmental Microbiology 73, no. 11 (2007): 3715–18. http://dx.doi.org/10.1128/aem.02398-06.

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ABSTRACT Variable-number tandem repeats (VNTRs) have been identified in populations of Pasteuria ramosa, a castrating endobacterium of Daphnia species. The allelic polymorphisms at 14 loci in laboratory and geographically diverse soil samples showed that VNTRs may serve as biomarkers for the genetic characterization of P. ramosa isolates.

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48

Parkinson, Neil, Ruth Bryant, Janice Bew, et al. "Application of Variable-Number Tandem-Repeat Typing To Discriminate Ralstonia solanacearum Strains Associated with English Watercourses and Disease Outbreaks." Applied and Environmental Microbiology 79, no. 19 (2013): 6016–22. http://dx.doi.org/10.1128/aem.01219-13.

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ABSTRACTVariable-number tandem-repeat (VNTR) analysis was used for high-resolution discrimination amongRalstonia solanacearumphylotype IIB sequevar 1 (PIIB-1) isolates and further evaluated for use in source tracing. Five tandem-repeat-containing loci (comprising six tandem repeats) discriminated 17 different VNTR profiles among 75 isolates from potato, geranium, bittersweet (Solanum dulcamara), tomato, and the environment.R. solanacearumisolates from crops at three unrelated outbreak sites where river water had been used for irrigation had distinct VNTR profiles that were shared with PIIB-1 i

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49

Levdansky, Emma, Jacob Romano, Yona Shadkchan, et al. "Coding Tandem Repeats Generate Diversity in Aspergillus fumigatus Genes." Eukaryotic Cell 6, no. 8 (2007): 1380–91. http://dx.doi.org/10.1128/ec.00229-06.

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ABSTRACT Genes containing multiple coding mini- and microsatellite repeats are highly dynamic components of genomes. Frequent recombination events within these tandem repeats lead to changes in repeat numbers, which in turn alters the amino acid sequence of the corresponding protein. In bacteria and yeasts, the expansion of such coding repeats in cell wall proteins is associated with alterations in immunogenicity, adhesion, and pathogenesis. We hypothesized that identification of repeat-containing putative cell wall proteins in the human pathogen Aspergillus fumigatus may reveal novel pathogen

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50

Papadopoulou, E., N. Gale, S. A. Goodchild, et al. "Strain discrimination of Yersinia pestis using a SERS-based electrochemically driven melting curve analysis of variable number tandem repeat sequences." Chemical Science 6, no. 3 (2015): 1846–52. http://dx.doi.org/10.1039/c4sc03084b.

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Abstract:

Variable number tandem repeats in DNA extracted from three bacterialY. pestisstrains have been differentiated usingE-melting analysis monitored by SERS, combined with the use of a blocker oligonucleotide.

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