Dissertations / Theses on the topic 'Variation (Biologie)'
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Hutter, Stephan. "Natural variation in Drosophila melanogaster." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-74185.
Full textCisneros, Caballero Angel Fernando, and Caballero Angel Fernando Cisneros. "The role of structural pleiotropy in the retention of protein complexes after gene duplication." Master's thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37529.
Full textLa duplication de gènes est l’un des plus importants mécanismes évolutifs pour la génération de diversité fonctionelle. Lorsqu’un gène est dupliqué, la nouvelle copie partage toutes ses fonctions avec la copie ancestrale car elles encodent pour des protéines identiques. Donc, les deux protéines, appelées paralogues, auront le même réseau d’interactions physiques protéine-protéine. Cependant, dans le cas de la duplication des gènes qui codent des protéines qui interagissent avec elles-mêmes (homomères), la nouvelle protéine interagira aussi avec la copie ancestrale, ce qui introduit une nouvelle interaction (heteromère) (Kaltenegger and Ober, 2015; Pereira-Leal et al., 2007). Puisque ces interactions peuvent avoir des différents motifs de rétention et de fonction (Ashenberg et al., 2011; Baker et al., 2013; Boncoeur et al., 2012; Bridgham et al., 2008), il est important de mieux comprendre comment ces états sont atteints et quelles forces évolutives les favorisent. Dans ce memoire, je cible ces questions avec des simulations in silico de l’évolution des protéines suite à la duplication de gènes en travaillant avec des structures crystallographiques de haute qualité, provenant de la Protein Data Bank (Berman et al., 2000; Dey et al., 2018). Les simulations montrent que les sous-unités et interfaces partagées entraînent une forte corrélation entre les trajectoires évolutives de ces complexes. Ainsi, les simulations prédisent que la préservation de seulement les deux homomères ou seulement l’hétéromère ne devrait pas être fréquente. Toutefois, la simulation qui applique la sélection seulement sur un homomère montre que l’homomère neutre est destabilisé plus rapidement que l’hétéromère neutre. Nous avons comparé ces prédictions avec des résultats expérimentaux du réseau d’interactions protéine-protéine de la levure. Comme suggéré par les simulations, les patrons d’interactions les plus fréquents ont été la formation des trois complexes (deux homomères et un hétéromère) ou la formation de seulement un homomère. Les patrons correspondants à deux homomères sans hétéromères ou un hétéromère sans homomères sont rares. Nos résultats démontrent l’extension de l’hétéromérisation entre paralogues dans le réseau d’interactions physiques protéine-protéine de la levure, les mécanismes sous-jacents et ses implications.
Gene duplication is one of the most important evolutionary mechanisms for the generation of functional diversity. When a gene is duplicated, the new copy shares all of the ancestral copy’s functions because they encode identical proteins. Therefore, the two proteins, called paralogs, will have the same protein-protein interaction network. However, in the case of the duplication of genes encoding proteins that self-interact (homomers), the new protein will also interact with the ancestral copy, introducing a novel interaction (heteromer) (Kaltenegger and Ober, 2015; Pereira-Leal et al., 2007). As these interactions can have different retention and functional patterns (Ashenberg et al., 2011; Baker et al., 2013; Boncoeur et al., 2012; Bridgham et al., 2008), it is important to understand better how these states are reached and what evolutionary forces favor each of them. In this thesis, I approach these questions by means of in silico simulations of protein evolution after gene duplication by working with high-quality crystal structures from the Protein Data Bank (Berman et al., 2000; Dey et al., 2018). The simulations show that the shared subunits and interfaces lead to these complexes having highly correlated evolutionary trajectories. Thus, the simulations predict that the preservation of only the two homomers or only the heteromer is not likely to happen often. Nevertheless, simulating evolution with selection on only one homomer shows that the neutral homomer is destabilized faster than the neutral heteromer. We compared these predictions against experimental results from the yeast protein-protein interaction network. As suggested by the simulations, the most abundant interaction patterns were either the formation of all three complexes (two homomers and one heteromer) or the formation of only one homomer, with motifs corresponding to two homomers without a heteromer or a heteromer without homomers being rare. Our results highlight the extent of heteromerization between paralogs in the yeast protein-protein interaction network, the underlying mechanisms, and its implications
Gene duplication is one of the most important evolutionary mechanisms for the generation of functional diversity. When a gene is duplicated, the new copy shares all of the ancestral copy’s functions because they encode identical proteins. Therefore, the two proteins, called paralogs, will have the same protein-protein interaction network. However, in the case of the duplication of genes encoding proteins that self-interact (homomers), the new protein will also interact with the ancestral copy, introducing a novel interaction (heteromer) (Kaltenegger and Ober, 2015; Pereira-Leal et al., 2007). As these interactions can have different retention and functional patterns (Ashenberg et al., 2011; Baker et al., 2013; Boncoeur et al., 2012; Bridgham et al., 2008), it is important to understand better how these states are reached and what evolutionary forces favor each of them. In this thesis, I approach these questions by means of in silico simulations of protein evolution after gene duplication by working with high-quality crystal structures from the Protein Data Bank (Berman et al., 2000; Dey et al., 2018). The simulations show that the shared subunits and interfaces lead to these complexes having highly correlated evolutionary trajectories. Thus, the simulations predict that the preservation of only the two homomers or only the heteromer is not likely to happen often. Nevertheless, simulating evolution with selection on only one homomer shows that the neutral homomer is destabilized faster than the neutral heteromer. We compared these predictions against experimental results from the yeast protein-protein interaction network. As suggested by the simulations, the most abundant interaction patterns were either the formation of all three complexes (two homomers and one heteromer) or the formation of only one homomer, with motifs corresponding to two homomers without a heteromer or a heteromer without homomers being rare. Our results highlight the extent of heteromerization between paralogs in the yeast protein-protein interaction network, the underlying mechanisms, and its implications
Loës, Corinna. "Variation in sleep behaviour and its underlying causes." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-149876.
Full textAraya-Ajoy, Yimen G. "Multi-level variation in labile characters." Diss., Ludwig-Maximilians-Universität München, 2015. http://nbn-resolving.de/urn:nbn:de:bvb:19-185184.
Full textMontero, Terrazas Juan Carlos [Verfasser], and Albert [Akademischer Betreuer] Reif. "Floristic variation of the Igapó Forests along the Negro River, Central Amazonia = Floristische Variation der Igapó Wälder entlang des Rio Negro, Zentral Amazonien." Freiburg : Universität, 2012. http://d-nb.info/1122592426/34.
Full textMartin, Jean-Louis. "Variation géographique, adaptation et spéciation : l'exemple de Parus caeruleus (Aves)." Montpellier 2, 1988. http://www.theses.fr/1988MON20233.
Full textRaess, Michael. "Annual timing and life-history variation in free-living stonechats." Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-63313.
Full textBoell, Louis A. [Verfasser]. "Variation und Variabilität der Unterkieferform in der Hausmaus / Louis A. Boell." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1020001011/34.
Full textDavid, Bruno. "La variation chez les Echinidés irréguliers : dimensions ontogénétiques, écologiques, évolutives." Dijon, 1985. http://www.theses.fr/1985DIJOS004.
Full textWarthmann, Norman [Verfasser]. "Finding the Causal Genes: Developing Tools for Natural Variation Research / Norman Warthmann." München : Verlag Dr. Hut, 2012. http://d-nb.info/1028785836/34.
Full textBerg, Wiebke [Verfasser], and Kathrin [Akademischer Betreuer] Dausmann. "Metabolic responses to environmental variation in tropical reptiles / Wiebke Berg ; Betreuer: Kathrin Dausmann." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2017. http://d-nb.info/1128820447/34.
Full textBerg, Wiebke Verfasser], and Kathrin H. [Akademischer Betreuer] [Dausmann. "Metabolic responses to environmental variation in tropical reptiles / Wiebke Berg ; Betreuer: Kathrin Dausmann." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2017. http://nbn-resolving.de/urn:nbn:de:gbv:18-84374.
Full textTams, Verena [Verfasser], and Mathilde [Akademischer Betreuer] Cordellier. "Intraspecific phenotypic variation and its genetic basis in Daphnia / Verena Tams ; Betreuer: Mathilde Cordellier." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2018. http://d-nb.info/117288062X/34.
Full textJax, Elinor [Verfasser]. "Immunology going wild : genetic variation and immunocompetence in the mallard (Anas platyrhynchos) / Elinor Jax." Konstanz : KOPS Universität Konstanz, 2019. http://d-nb.info/1189593912/34.
Full textMignot, Emmanuel. "Étude des cinétiques de variation des métabolites des monoamines dans le LCR du rat." Paris 6, 1986. http://www.theses.fr/1986PA066593.
Full textHarter, David Verfasser], and Carl [Akademischer Betreuer] [Beierkuhnlein. "Eco-evolutionary responses of plants to spatial and temporal climatic variation / David Harter. Betreuer: Carl Beierkuhnlein." Bayreuth : Universität Bayreuth, 2016. http://d-nb.info/1097378837/34.
Full textAckermann, Marit [Verfasser], Katja [Akademischer Betreuer] Ickstadt, and Jörg [Gutachter] Rahnenführer. "Discovering genetic interactions based on natural genetic variation / Marit Ackermann. Betreuer: Katja Ickstadt. Gutachter: Jörg Rahnenführer." Dortmund : Universitätsbibliothek Dortmund, 2012. http://d-nb.info/1103586823/34.
Full textHarter, David [Verfasser], and Carl [Akademischer Betreuer] Beierkuhnlein. "Eco-evolutionary responses of plants to spatial and temporal climatic variation / David Harter. Betreuer: Carl Beierkuhnlein." Bayreuth : Universität Bayreuth, 2016. http://d-nb.info/1097378837/34.
Full textRoth, Patrick [Verfasser], and Ulrich [Gutachter] Schatzschneider. "Metalltricarbonyl-basierte CO-releasing molecules (CORMs): Variation der Freisetzungskinetik und Biokonjugation / Patrick Roth ; Gutachter: Ulrich Schatzschneider." Würzburg : Universität Würzburg, 2021. http://d-nb.info/1236547950/34.
Full textGroßbach, Jan [Verfasser], Andreas [Gutachter] Beyer, and Achim [Gutachter] Tresch. "Identification and Validation of Regulatory Genetic Variation in Yeasts / Jan Großbach ; Gutachter: Andreas Beyer, Achim Tresch." Köln : Universitäts- und Stadtbibliothek Köln, 2019. http://d-nb.info/1219652342/34.
Full textMerlin, Francesca. "Le hasard et les sources de la variation biologique : analyse critique d'une notion multiple." Phd thesis, Université Panthéon-Sorbonne - Paris I, 2009. http://tel.archives-ouvertes.fr/tel-00397641.
Full textpopulations naturelles. Plus exactement, nous abordons la question de savoir quelle notion de hasard est conceptuellement et empiriquement appropriée en ce qui concerne deux sources de variation biologique : les mutations génétiques et le bruit dans l'expression des gènes. Nous
apportons une clarification conceptuelle de cette notion, selon une perspective évolutionnaire et d'un point de vue moléculaire, sur la base des avancées récentes au sujet de ces deux causes de la variation. En vertu de la relation apparemment privilégiée entre la notion de hasard et les probabilités, nous traitons aussi la question de l'interprétation des probabilités dans les descriptions formelles de ces phénomènes biologiques. L'objectif principal de ce travail est de fournir un cadre conceptuel précis à l'utilisation de la notion de hasard en biologie.
Mutzel, Ariane. "The role of parental care in shaping personality-related variation in reproductive success in free-living passerines." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-163919.
Full textJuszczak, Ilona [Verfasser]. "Natural genetic variation in the expression regulation of chloroplast antioxidant system among A. thaliana accessions. / Ilona Juszczak." Berlin : Freie Universität Berlin, 2013. http://d-nb.info/1042441324/34.
Full textDebieu, Marilyne [Verfasser], and Maarten [Akademischer Betreuer] Koornneef. "Comprehensive phenotypic and genomic analyses of life-cycle variation in Arabidopsis thaliana / Marilyne Debieu. Gutachter: Maarten Koornneef." Köln : Universitäts- und Stadtbibliothek Köln, 2011. http://d-nb.info/1038064252/34.
Full textSchmidt, Gesine [Verfasser], and Matthias [Akademischer Betreuer] Köck. "Secondary Metabolites in the Arctic Sponge Haliclona viscosa - Spatial and Temporal Variation / Gesine Schmidt ; Betreuer: Matthias Köck." Braunschweig : Technische Universität Braunschweig, 2010. http://d-nb.info/117582688X/34.
Full textDrewe, Philipp [Verfasser], and Daniel [Akademischer Betreuer] Huson. "Detection and characterisation of RNA processing variation from deep RNA sequencing data / Philipp Drewe ; Betreuer: Daniel Huson." Tübingen : Universitätsbibliothek Tübingen, 2016. http://d-nb.info/1168011264/34.
Full textGáspár, Bence [Verfasser], and Oliver [Akademischer Betreuer] Bossdorf. "Evolutionary consequences of land use – Epigenetic and phenotypic variation in Plantago lanceolata / Bence Gáspár ; Betreuer: Oliver Bossdorf." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1212025369/34.
Full textAraya-Ajoy, Yimen G. [Verfasser], and Niels [Akademischer Betreuer] Dingemanse. "Multi-level variation in labile characters : adaptive causes and evolutionary consequences / Yimen G. Araya-Ajoy. Betreuer: Niels Dingemanse." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1075456711/34.
Full textHerz, Katharina [Verfasser]. "Drivers of intraspecific variation of plant functional traits, plant performance and root exudates in German grasslands / Katharina Herz." Halle, 2017. http://d-nb.info/1142155315/34.
Full textBen, Abdallah Heithem [Verfasser]. "Natural variation in leguminous species and rice shows physiological and molecular adaptation to abiotic stress / Heithem Ben Abdallah." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2018. http://d-nb.info/1160085641/34.
Full textHooi, Wei Yeng. "Search for early molecular markers of the mantled floral variation of oil palm." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS244.
Full textProject title : Search for early molecular markers of the mantled floral variation of oil palmObjectives : - identifying expression markers of the mantled somaclonal variation through the comparison between the true-to-type and the variant transcriptome. - assessing the discriminating power of the selected markers at early stages of the in vitro process.Strategy and Methods : Transcriptomic analysis of the normal oil palm inflorescence, construction of a reference transcriptome. Technique : RNAseq, Illumina sequencing.Identification of sequences and pathways of interest. Technique : bioinformatic analysis of sequencing data.Comparison between the normal and the mantled inflorescence transcriptome through the re-sequencing of libraries generated from several different clonal lines. Technique : Illumina. Identification of sequences displaying consistently a phenotype-dependent differential expression pattern. Technique : bioinformatic analysis of sequencing data, statistical analysis of expression patterns. Validation of candidate markers on normal/mantled regenerant palm pairs from different clonal lines and on normal-/mantled-derived in vitro cultures at various stages of the industrial regeneration process. Technique : quantitative PCR (q-PCR)
Müller, Niels [Verfasser], and Maarten [Akademischer Betreuer] Koornneef. "Natural variation in circadian rhythms and photoperiodic flowering in tomato and its wild relatives / Niels Müller. Gutachter: Maarten Koornneef." Köln : Universitäts- und Stadtbibliothek Köln, 2014. http://d-nb.info/1072500507/34.
Full textZhang, Lei [Verfasser], and George [Gutachter] Coupland. "Identification and Characterization of Genes underlying Natural variation in Flowering Time in Arabidopsis thaliana / Lei Zhang ; Gutachter: George Coupland." Köln : Universitäts- und Stadtbibliothek Köln, 2017. http://d-nb.info/1162273534/34.
Full textMajda, Stephan [Verfasser], and Jens [Akademischer Betreuer] Boenigk. "Evolution in Chrysophyceae regarding the nutritional mode and intraspecific variation based on comparative genomics / Stephan Majda ; Betreuer: Jens Boenigk." Duisburg, 2020. http://d-nb.info/1233199943/34.
Full textBarragan, Lopez Ana Cristina [Verfasser]. "A Dangerous Mix : From Natural Variation to Genetic Incompatibilities in Arabidopsis thaliana and Arabidopsis arenosa / Ana Cristina Barragan Lopez." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1224232798/34.
Full textForneris, Mattia [Verfasser], and Oliver [Akademischer Betreuer] Stegle. "Natural sequence variation as a tool to dissect gene expression regulation in Drosophila melanogaster / Mattia Forneris ; Betreuer: Oliver Stegle." Heidelberg : Universitätsbibliothek Heidelberg, 2020. http://d-nb.info/1221019171/34.
Full textSchäfer, Barbara Nicole [Verfasser], Klaus [Akademischer Betreuer] Theres, and Wolfgang [Akademischer Betreuer] Werr. "Identifizierung und Charakterisierung neuer Verzweigungsregulatoren durch Verwendung natürlicher Variation in Arabidopsis thaliana / Barbara Nicole Schäfer. Gutachter: Klaus Theres ; Wolfgang Werr." Köln : Universitäts- und Stadtbibliothek Köln, 2012. http://d-nb.info/1038234182/34.
Full textTergemina, Emmanuel [Verfasser], George [Gutachter] Coupland, Ute [Gutachter] Höcker, Maria [Gutachter] Albani, and Franziska [Gutachter] Turck. "Natural variation at FLOWERING LOCUS T in Arabidopsis thaliana / Emmanuel Tergemina ; Gutachter: George Coupland, Ute Höcker, Maria Albani, Franziska Turck." Köln : Universitäts- und Stadtbibliothek Köln, 2017. http://d-nb.info/1163012939/34.
Full textVenu, Vrinda [Verfasser], and Felicity [Akademischer Betreuer] Jones. "Genomic insights into fine-scale recombination variation in adaptively diverging threespine stickleback fish (Gasterosteus aculeatus) / Vrinda Venu ; Betreuer: Felicity Jones." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/120783114X/34.
Full textCostea, Paul Igor [Verfasser], Thomas [Gutachter] Dandekar, and Peer [Gutachter] Bork. "Stratification and variation of the human gut microbiota / Paul Igor Costea ; Gutachter: Thomas Dandekar, Peer Bork." Würzburg : Universität Würzburg, 2016. http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-139649.
Full textCostea, Paul Igor Verfasser], Thomas [Gutachter] [Dandekar, and Peer [Gutachter] Bork. "Stratification and variation of the human gut microbiota / Paul Igor Costea ; Gutachter: Thomas Dandekar, Peer Bork." Würzburg : Universität Würzburg, 2016. http://d-nb.info/1117477312/34.
Full textLi, Dan. "Phenotypic variation and molecular signaling in the interaction of the rhizosphere bacteria Acidovorax sp. N35 and Rhizobium radiobacter F4 with roots." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-126570.
Full textMalyshev, Andrey [Verfasser], and Jürgen [Akademischer Betreuer] Kreyling. "Plant growth responses to winter climate change: from amongand within-species variation to plant-soil interactions / Andrey Malyshev. Betreuer: Jürgen Kreyling." Bayreuth : Universität Bayreuth, 2015. http://d-nb.info/1074461851/34.
Full textAkter, Pervin [Verfasser], Petr [Akademischer Betreuer] [Gutachter] Karlovsky, and Franz [Gutachter] Hadacek. "Plant Root Exudates : Variation between Species and Reaction to Water Deficit / Pervin Akter ; Gutachter: Petr Karlovsky, Franz Hadacek ; Betreuer: Petr Karlovsky." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/1125105968/34.
Full textKarelina, Darya [Verfasser], and Detlef [Akademischer Betreuer] Weigel. "Genome-Wide Analysis of Nucleotide-Binding Domain Leucine-Rich Repeat (NLR) Variation Patterns in Arabidopsis thaliana / Darya Karelina ; Betreuer: Detlef Weigel." Tübingen : Universitätsbibliothek Tübingen, 2019. http://d-nb.info/1188642022/34.
Full textGroll, Fanny [Verfasser], v. [Gutachter], and Joachim [Gutachter] Krug. "Diversity and Stability in Food Webs : Impacts of Non-Equilibrium Dynamics, Topology and Variation / Fanny Groll ; Gutachter: Alexander Altland, Joachim Krug." Köln : Universitäts- und Stadtbibliothek Köln, 2016. http://d-nb.info/1122713843/34.
Full textIlk, Nadine [Verfasser], Maarten [Akademischer Betreuer] Koornneef, and Ute [Akademischer Betreuer] Höcker. "Genetic bases of plant performance in different environmental scenarios using natural variation in Arabidopsis thaliana / Nadine Ilk. Gutachter: Maarten Koornneef ; Ute Höcker." Köln : Universitäts- und Stadtbibliothek Köln, 2012. http://d-nb.info/1038226171/34.
Full textRomanov, Natalie [Verfasser], Peer [Gutachter] Bork, and Thomas [Gutachter] Dandekar. "Characterizing Variation of Protein Complexes and Functional Modules on a Temporal Scale and across Individuals / Natalie Romanov ; Gutachter: Peer Bork, Thomas Dandekar." Würzburg : Universität Würzburg, 2019. http://d-nb.info/1194836216/34.
Full textFischer, Sina [Verfasser], and Stephan [Akademischer Betreuer] Clemens. "Untersuchung der natürlichen Variation der Metalltoleranz von Arabidopsis thaliana Ökotypen und Identifikation von Genen verantwortlich für Toleranzunterschiede / Sina Fischer ; Betreuer: Stephan Clemens." Bayreuth : Universität Bayreuth, 2018. http://d-nb.info/1159632871/34.
Full textSchießl-Weidenweber, Sarah [Verfasser]. "The role of genome structure variation in the evolution and adaptation of life cycle traits in Brassica species / Sarah Schießl-Weidenweber." Gießen : Universitätsbibliothek, 2021. http://d-nb.info/1230476121/34.
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