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Journal articles on the topic 'Variation (Biologie)'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 February 2023

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1

OLSSON, P. G. "Studien über die Variation des Choleravirus in Bezug auf Biologie und Virulenz." Nordiskt Medicinskt Arkiv 47, no. 10 (2009): 1–101. http://dx.doi.org/10.1111/j.0954-6820.1914.tb01550.x.

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Pailler, Thierry, Benjamin Warren, and Jean-Noël Labat. "Biologie de la reproduction de Aloe mayottensis (Liliaceae), une espèce endémique de l'île Mayotte (Océan Indien)." Canadian Journal of Botany 80, no. 4 (2002): 340–48. http://dx.doi.org/10.1139/b02-019.

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A particularly interesting aspect of the study of organisms in insular environments is plant reproduction and the interaction of plants with their pollinators. Differences in composition between the fauna and flora of continental and island populations, combined with their geographical isolation, have frequently driven rapid evolution in colonizing populations. In particular, floral traits and compatibility systems tend to favour autogamy in response to a paucity of pollinators in the environment. In this context we investigate the origins of the reproductive biology of Aloe mayottensis Berger

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Ntumba Mabedi, Jean Métis, Victorine Mbadu Zebe, Johan R. Michaux, and Jean-Claude Micha. "Biologie de la reproduction des Marcusenius (M. monteiri, M. stanleyanus, M. schilthuisiae et M. macrolepidotus) du Pool Malebo, fleuve Congo, Kinshasa." International Journal of Biological and Chemical Sciences 16, no. 2 (2022): 564–80. http://dx.doi.org/10.4314/ijbcs.v16i2.5.

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Les informations sur la biologie de la reproduction des poissons du genre Marcusenius vivant au pool Malebo, sont peu connues. Pourtant, leur exploitation très importante actuellement se fait sans tenir compte du renouvellement de leurs stocks. Cette étude avait comme objectif de déterminer les stratégies de reproduction de quatre espèces du genre Marcusenius les plus abondantes dans les captures effectuées à l’aide des filets maillants dormants au niveau du pool Malebo. Les quatre espèces de Marcusenius récoltés ont une seule gonade gauche bien développée avec de grands ovocytes presque de mê

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Hilley, P., C. Li Wai Suen, A. Srinivasan, M. C. Choy, and P. De Cruz. "P379 Variations in disease monitoring between Inflammatory Bowel Disease patients on intravenous and subcutaneous biologic agents." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S393. http://dx.doi.org/10.1093/ecco-jcc/jjab076.503.

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Abstract Background The availability of subcutaneous (SC) administration devices of biologics in addition to intravenous (IV) administration has influenced patients’ and clinicians’ preferences towards initiating or transitioning to SC administration particularly during the COVID-19 pandemic. Whilst SC administration improves patient convenience and reduces demands on infusion centres we hypothesised that the reduction in healthcare contact associated with SC therapies may reduce the opportunities available for objective disease assessment. We aimed to compare the uptake of objective assessmen

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Enos, Clinton W., Hadiza Galadima, Arjun D. Saini, Stacie Bell, Michael Siegel, and Abby S. Van Voorhees. "Predictors of Biologic Use and Satisfaction Among Patients With Psoriasis: An Analysis and Geographic Visualization of the 2016 and 2017 National Psoriasis Foundation Annual Surveys." Journal of Psoriasis and Psoriatic Arthritis 5, no. 3 (2020): 100–108. http://dx.doi.org/10.1177/2475530320925553.

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Background: There are an increasing number of biologic therapies approved for the treatment of psoriasis. Previous reports have identified undertreatment as a concern in the United States. Undertreatment has been associated with decreased patient satisfaction and increased morbidity. Objectives: Assess biologic use and satisfaction among respondents to the 2016 and 2017 National Psoriasis Foundation (NPF) Annual Surveys. Methods: Retrospective data analysis of the 2016 and 2017 NPF Annual Survey responses from individuals with psoriasis. ArcGIS Pro software was utilized to generate maps and pe

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Henderson, I. Craig. "Biologic variations of tumors." Cancer 69, S7 (1992): 1888–95. http://dx.doi.org/10.1002/1097-0142(19920401)69:7+<1888::aid-cncr2820691703>3.0.co;2-#.

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Galli, Emily, Guodong Liu, Doug Leslie, Joslyn Kirby, and Jeffrey J. Miller. "Prescription Pattern Variability of Biologic Therapies in Treating Psoriasis." Journal of Psoriasis and Psoriatic Arthritis 3, no. 3 (2018): 84–87. http://dx.doi.org/10.1177/2475530318781308.

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Background: Medical conditions with high variability in clinical costs and outcomes, such as psoriasis, represent a critical area for health-care value improvement. Thus, the prescription pattern variability of psoriasis biologics merits further study. Objective: The purpose of our study was to determine whether there is variation in psoriasis biologic prescribing patterns. Methods: This study analyzed data from the Truven MarketScan Commercial Claims and Encounters database. Patients with International Classification of Diseases, Ninth Revision psoriasis diagnoses from January 1, 2008, to Dec

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Ricós, Carmen, Virtudes Álvarez, Joana Minchinela, et al. "Biologic Variation Approach to Daily Laboratory." Clinics in Laboratory Medicine 37, no. 1 (2017): 47–56. http://dx.doi.org/10.1016/j.cll.2016.09.005.

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Moody, J. P. "Biologic Variation of Serum and Salivary Lithium." Therapeutic Drug Monitoring 21, no. 1 (1999): 97–101. http://dx.doi.org/10.1097/00007691-199902000-00015.

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Sledge, George W. "Innumerable Variations: Combining Biologics." Clinical Breast Cancer 9, no. 1 (2009): 7. http://dx.doi.org/10.3816/cbc.2009.n.001.

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11

Jerome, Rebecca N., Jill M. Pulley, Nila A. Sathe, et al. "Exploring Biologic Predictors of Response Disparities to Atypical Antipsychotics among Blacks: A Quasi-Systematic Review." Ethnicity & Disease 30, Suppl 1 (2020): 229–40. http://dx.doi.org/10.18865/ed.30.s1.229.

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Purpose: Management of schizophrenia among Blacks in the United States is affected by persistent disparities. This review explored response to atypical antipsychotics among Blacks compared with other groups to assess systematic variation that may contribute to disparities.Methods: We conducted a quasi-systematic review of studies reporting response to atypical antipsychotics among Blacks compared with other groups, including effects of genetic variation.Results: Of 48 identified research articles, 29 assessed differences in outcomes without inclusion of genetic variation and 20 explored ef

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Miller, J., J. Kirby, D. Leslie, G. Emily, and G. Liu. "202 Prescription variation of biologic therapies for psoriasis." Journal of Investigative Dermatology 136, no. 5 (2016): S36. http://dx.doi.org/10.1016/j.jid.2016.02.230.

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Bellini, Marilanda Ferreira, Rosana Silistino-Souza, Marileila Varella-Garcia, Maria Tercília Vilela de Azeredo-Oliveira, and Ana Elizabete Silva. "Biologic and Genetics Aspects of Chagas Disease at Endemic Areas." Journal of Tropical Medicine 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/357948.

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The etiologic agent of Chagas Disease is theTrypanosoma cruzi, transmitted through blood-sucking insect vectors of the Triatominae subfamily, representing one of the most serious public health concerns in Latin America. There are geographic variations in the prevalence of clinical forms and morbidity of Chagas disease, likely due to genetic variation of theT. cruziand the host genetic and environmental features. Increasing evidence has supported that inflammatory cytokines and chemokines are responsible for the generation of the inflammatory infiltrate and tissue damage. Moreover, genetic poly

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Kroll, Martin H. "Multiple Patient Samples of an Analyte Improve Detection of Changes in Clinical Status." Archives of Pathology & Laboratory Medicine 134, no. 1 (2010): 81–89. http://dx.doi.org/10.5858/2008-0652-oar1.1.

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Abstract Context. When comparing results over time, biologic variation must be statistically incorporated into the evaluation of laboratory results to identify a physiologic change. Traditional methods compare the difference in 2 values with the standard deviation (SD) of the biologic variation to indicate whether a “true” physiologic change has occurred. Objective. To develop methodology to reduce the effect of biologic variation on the difference necessary to detect changes in clinical status in the presence of biologic variation. Design. The standard test for change compares the difference

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Willett, N., C. G. Heisler, N. Nazer, et al. "P338 The effectiveness of a standardised biologic care pathway in the management and treatment of inflammatory bowel disease." Journal of Crohn's and Colitis 14, Supplement_1 (2020): S325. http://dx.doi.org/10.1093/ecco-jcc/jjz203.467.

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Abstract Background inflammatory bowel disease (IBD) is a class of chronic immune-mediated diseases. Biologics have revolutionised the treatment of IBD. Existing literature suggests significant variation exists in the use of biologic treatment among physicians, from provider-specific prescribing to completion of the pre-biologic workup. These differences may influence the effectiveness of achieving and maintaining long-term remission. Clinical care pathways can standardise the use of biologics, improve patient outcomes, and increase consistency of care. The aim of the project was to determine

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Willett, N., C. Heisler, N. Nazer, et al. "A157 THE EFFECTIVENESS OF A STANDARDIZED BIOLOGIC CARE PATHWAY IN THE MANAGEMENT AND TREATMENT OF INFLAMMATORY BOWEL DISEASE." Journal of the Canadian Association of Gastroenterology 3, Supplement_1 (2020): 21–22. http://dx.doi.org/10.1093/jcag/gwz047.156.

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Abstract Background Inflammatory Bowel Disease (IBD) is a class of chronic immune-mediated diseases. Biologics have revolutionized the treatment of IBD. Existing literature suggests significant variation exists in the use of biologic treatment among physicians, from provider-specific prescribing to completion of the pre-biologic workup. These differences may influence the effectiveness of achieving and maintaining long-term remission. Clinical care pathways may serve to standardize the use of biologics in the treatment of IBD leading to improvements in patient outcomes and consistency of care

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Heuser, Michael, and R. Keith Humphries. "Biologic and experimental variation of measured cancer stem cells." Cell Cycle 9, no. 5 (2010): 909–12. http://dx.doi.org/10.4161/cc.9.5.10852.

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Vasile, Vlad C., Amy K. Saenger, Jean M. Kroning, George G. Klee, and Allan S. Jaffe. "Biologic Variation of a Novel Cardiac Troponin I Assay." Clinical Chemistry 57, no. 7 (2011): 1080–81. http://dx.doi.org/10.1373/clinchem.2011.162545.

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Goettel, Andrea M., Josh DeClercq, Leena Choi, Thomas B. Graham, and Amy A. Mitchell. "Efficacy and Safety of Abatacept, Adalimumab, and Etanercept in Pediatric Patients With Juvenile Idiopathic Arthritis." Journal of Pediatric Pharmacology and Therapeutics 26, no. 2 (2021): 157–62. http://dx.doi.org/10.5863/1551-6776-26.2.157.

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OBJECTIVE The lack of randomized controlled trials comparing biologics for the treatment of juvenile idiopathic arthritis (JIA) has led to wide variation in treatment approaches. The objective of this study is to compare the efficacy and safety of abatacept, adalimumab, and etanercept in JIA patients treated at a tertiary pediatric institution. METHODS This was a single-center, retrospective chart review of patients initiated on abatacept, adalimumab, or etanercept from December 1, 2015, to August 31, 2018, at Monroe Carell Jr. Children's Hospital at Vanderbilt (VCH). The primary outcome was t

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Wang, Xiu-Mei, Xiangbing Yang, Lian-Sheng Zang, Zheng Wang, Chang-Chun Ruan, and Xian-Jiao Liu. "Effect of geographic variation on biology and cold tolerance of Harmonia axyridis in China." Entomologia Generalis 36, no. 3 (2017): 239–50. http://dx.doi.org/10.1127/entomologia/2017/0441.

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Putra, Aldy Darmansyah, Wildan Nurfalah, Emma Hermawati Muhari, and Muchtar Gozali. "Pemanfaatan Limbah Lumpur IPAL Proses Biologi Sebagai Bahan Bakar Alternatif dalam Bentuk Briket." Fluida 15, no. 2 (2022): 136–42. http://dx.doi.org/10.35313/fluida.v15i2.4522.

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Industrial WWTP sludge has not been used properly, especially biological process WWTP sludge can be used as an alternative fuel in the form of briquettes. The purpose of this study was to determine potential utilization of biological process WWTP sludge as briquettes, and to determine the effect of adding variations charcoal to the quality of briquettes. The biological process WWTP sludge was obtained from the Trio Food, Cianjur. The dried sludge has a calorific value 2468 cal/g. The research methodology includes material drying, size reduction (250 μm), mixing, molding, and briquette drying.

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Sander, P. M. "Life history of Tendaguru sauropods as inferred from long bone histology." Fossil Record 2, no. 1 (1999): 103–12. http://dx.doi.org/10.1002/mmng.1999.4860020107.

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Abstract. Sauropod dinosaurs present exceptional challenges in understanding their biology because of their exceptional body size. One of these, life history, can be inferred from the histology of their bones. For this purpose, the diverse sauropod assemblage of the Upper Jurassic Tendaguru beds was sampled with a new coring method which provided unprecented access to and insights into sauropod bone histology. Growth series of humeri and femora as well as long growth records from single bones suggest that all four sauropod taxa are characterized by continued growth after sexual maturity but th

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Anisdahl, K., S. S. Lirhus, A. W. Medhus, B. Moum, H. O. Melberg, and M. L. Høivik. "P882 Regional differences in biologic and surgical treatment of inflammatory bowel disease in Norway 2011–2019." Journal of Crohn's and Colitis 17, Supplement_1 (2023): i999—i1001. http://dx.doi.org/10.1093/ecco-jcc/jjac190.1012.

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Abstract Background We have previously reported regional differences in biologic and surgical treatment for inflammatory bowel disease (IBD) patients diagnosed 2010–2012. In this study, our aim was to explore whether regional differences in the use of biologics and surgery were consistent over time. Methods We performed a nationwide, observational study using linked data from the Norwegian Patient Registry (NPR) and the Norwegian Prescription Database (Nor-PD). Incident cases were defined as ≥2 IBD diagnosis codes in the NPR, or ≥1 IBD diagnosis code in the NPR and ≥2 IBD prescriptions in the

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Ockene, Ira S., Charles E. Matthews, Nader Rifai, Paul M. Ridker, George Reed, and Edward Stanek. "Variability and Classification Accuracy of Serial High-Sensitivity C-Reactive Protein Measurements in Healthy Adults." Clinical Chemistry 47, no. 3 (2001): 444–50. http://dx.doi.org/10.1093/clinchem/47.3.444.

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Abstract Background: Increased concentrations of high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, are associated with increased risk for coronary heart disease. Because of its relationship to inflammation, hs-CRP has considerable biologic variation. This study was carried out to characterize CRP variation and to compare it to another risk factor, total serum cholesterol. Methods: One hundred thirteen individuals were scheduled to have five measurements each of hs-CRP and total cholesterol carried out at quarterly intervals over a 1-year period. Variations of hs-

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Roach, A., I. Scott, G. Macfarlane, G. T. Jones, and A. Macgregor. "OP0284 AN AGENT-BASED SIMULATION OF THE EFFECTS OF VARYING TIME TO TREATMENT WITH BIOLOGICAL AGENTS ON PATIENT HEALTH AND COST IN AXIAL SPONDYLOARTHRITIS USING NATIONAL REGISTER DATA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 177.1–177. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1507.

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Background:Evaluating the long-term impacts of healthcare policies on patient’s health and treatment costs for people with axial spondyloarthritis (axSpA) is challenging due to its chronic nature, and the variation in individual patient journeys post-diagnosis. Agent-based simulations are a novel approach to interrogating this complexity, and allow the consequences of different policy scenarios on outcomes to be explored.Objectives:Develop and validate an agent-based simulation of the UK axial spondyloarthritis healthcare system, using real-world data.Interrogate the effects of earlier biologi

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Otremski, I., M. Katz, G. Livshits, and Z. Cohen. "Biology of aging in an Israeli population. 1. Review of literature and morphological variation analysis." Anthropologischer Anzeiger 51, no. 3 (1993): 233–49. http://dx.doi.org/10.1127/anthranz/51/1993/233.

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Fraser, Callum G., Stephen P. Wilkinson, Ronald G. Neville, James D. E. Knox, John F. King, and Ronald S. Macwalter. "Biologic Variation of Common Hematologic Laboratory Quantities in the Elderly." American Journal of Clinical Pathology 92, no. 4 (1989): 465–70. http://dx.doi.org/10.1093/ajcp/92.4.465.

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Andersen, Stig, Niels Henrik Bruun, Klaus Michael Pedersen, and Peter Laurberg. "Biologic Variation is Important for Interpretation of Thyroid Function Tests." Thyroid 13, no. 11 (2003): 1069–78. http://dx.doi.org/10.1089/105072503770867237.

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Jongerius, Peter H., Jacques van Limbeek, and Jan J. Rotteveel. "Assessment of Salivary Flow Rate: Biologic Variation and Measure Error." Laryngoscope 114, no. 10 (2004): 1801–4. http://dx.doi.org/10.1097/00005537-200410000-00023.

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Kuzma, Kori, James Stevenson, Jiachen Liu, et al. "21. Translating human readable variation descriptions to unique computable variations with the Variation Normalizer." Cancer Genetics 268-269 (November 2022): 7–8. http://dx.doi.org/10.1016/j.cancergen.2022.10.024.

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Cohen, Claudine. "De la biologie au roman : le modèle morphologique et ses variations." Romantisme 138, no. 4 (2007): 47. http://dx.doi.org/10.3917/rom.138.0047.

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de Jong, Daphne, Andreas Rosenwald, Mukesh Chhanabhai, et al. "Immunohistochemical Prognostic Markers in Diffuse Large B-Cell Lymphoma: Validation of Tissue Microarray As a Prerequisite for Broad Clinical Applications—A Study From the Lunenburg Lymphoma Biomarker Consortium." Journal of Clinical Oncology 25, no. 7 (2007): 805–12. http://dx.doi.org/10.1200/jco.2006.09.4490.

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Purpose The results of immunohistochemical class prediction and prognostic stratification of diffuse large B-cell lymphoma (DLBCL) have been remarkably various thus far. Apart from biologic variations, this may be caused by differences in laboratory techniques, scoring definitions, and inter- and intraobserver variations. In this study, an international collaboration of clinical lymphoma research groups from Europe, United States, and Canada concentrated on validation and standardization of immunohistochemistry of the currently potentially interesting prognostic markers in DLBCL. Patients and

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Fernandes, Laísa, and Patricia Shirley Prado. "Submental Anatomical Variations: The Uniqueness of a Common Variation." Journal of Morphological Sciences 38 (2021): 100–108. http://dx.doi.org/10.51929/jms.38.19.2021.

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Cembrowski, George S., Andrew W. Lyon, Christopher McCudden, et al. "Transformation of Sequential Hospital and Outpatient Laboratory Data into Between-Day Reference Change Values." Clinical Chemistry 68, no. 4 (2022): 595–603. http://dx.doi.org/10.1093/clinchem/hvab271.

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Abstract Background Serial differences between intrapatient consecutive measurements can be transformed into Taylor series of variation vs time with the intersection at time = 0 (y0) equal to the total variation (analytical + biological + preanalytical). With small preanalytical variation, y0, expressed as a percentage of the mean, is equal to the variable component of the reference change value (RCV) calculation: (CVA2 + CVI2)1/2. Methods We determined the between-day RCV of patient data for 17 analytes and compared them to healthy participants’ RCVs. We analyzed 653 consecutive days of Dartm

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Salomo, Salomo, Nova Lestari, and Muhammad Hamdi. "ANALISA PENGARUH GAYA ELEKTROSTATIK PADA SPEKTRUM PENCITRAAN RESONANSI MAGNETIK (MRI) DALAM JARINGAN BIOLOGI." Komunikasi Fisika Indonesia 16, no. 1 (2019): 8. http://dx.doi.org/10.31258/jkfi.16.1.8-11.

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A study of magnetic core resonance imaging modeling of biological tissue has been carried out in analyzing the effect of electrostatic forces with computational approach. This analysis aims to look at the effect of electric and magnetic force on the spectrum of breast cancer tissue. Physical parameters were determined using the modeled wave equation with the application of mathematical wolfram software 9. Computational or modeling results obtained 6 variations of the MRI spectrum showing the peak magnitude of the electric and magnetic spectrum changes by varying the resolution and distance. Th

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Cooper, G. R., S. J. Smith, G. L. Myers, E. J. Sampson, and E. Magid. "Estimating and minimizing effects of biologic sources of variation by relative range when measuring the mean of serum lipids and lipoproteins." Clinical Chemistry 40, no. 2 (1994): 227–32. http://dx.doi.org/10.1093/clinchem/40.2.227.

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Abstract Biologic intraindividual variation (CVb) is a major source of inaccuracy in current lipid and lipoprotein measurements. Metaanalysis has been used to estimate the average CVb of serum total cholesterol (TC), high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), and triglyceride (TG). These CVb values are larger than the National Cholesterol Education Program-accepted and -proposed analytic (CVa) goals. Measuring serial specimens reduces the error in determination of the mean concentration used in classification of the patient by cutoff points. We sho

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Freeman, Kathleen P., Randolph M. Baral, Navneet K. Dhand, Søren Saxmose Nielsen, and Asger L. Jensen. "Recommendations for designing and conducting veterinary clinical pathology biologic variation studies." Veterinary Clinical Pathology 46, no. 2 (2017): 211–20. http://dx.doi.org/10.1111/vcp.12475.

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Prieto, Jennifer M., Patrick C. Carney, Meredith L. Miller, et al. "Biologic variation of symmetric dimethylarginine and creatinine in clinically healthy cats." Veterinary Clinical Pathology 49, no. 3 (2020): 401–6. http://dx.doi.org/10.1111/vcp.12884.

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Khankari, Nikhil K., Patrick T. Bradshaw, Lauren E. McCullough, et al. "Genetic variation in multiple biologic pathways, flavonoid intake, and breast cancer." Cancer Causes & Control 25, no. 2 (2013): 215–26. http://dx.doi.org/10.1007/s10552-013-0324-8.

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Patterson, K. David. "Biologic variation in health and illness: Race, age and sex differences." Social Science & Medicine 43, no. 8 (1996): 1297. http://dx.doi.org/10.1016/0277-9536(96)85827-8.

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Gohil, S. "AB1343-HPR A QUALITATIVE REVIEW ASSESSING THEMATIC OUTCOMES FROM THE PHARMACY-LED ADALIMUMAB BIOSIMILAR SWITCH PLAN ACROSS 3 SPECIALITIES; RHEUMATOLOGY, GASTROENTEROLOGY AND DERMATOLOGY AT UNIVERSITY HOSPITALS OF COVENTRY AND WARWICKSHIRE (UHCW)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1959.1–1960. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3880.

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Background:The advent of biosimilars has heralded a new era for cost effective biologic prescribing in the NHS. As patents expire for originator biologics, less expensive versions are now widely available as biosimilars. Non-medical switches (for reasons unrelated to a patient’s health) ensure prescribing of best value medicines, and cost savings can be redirected to patient care.1This practice resonates with recommendations from Lord Carter’s 2016 report regarding reducing unwarranted variation in the NHS and adopting cost saving opportunities.2In 2018/19, following loss of patent exclusivity

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Huynh, L., S. Hass, B. E. Sands, et al. "P621 Physician preferences for biologics (originator vs. biosimilar) for the treatment of ulcerative colitis in France, Germany and the UK." Journal of Crohn's and Colitis 14, Supplement_1 (2020): S515—S516. http://dx.doi.org/10.1093/ecco-jcc/jjz203.749.

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Abstract Background Although originator biologics are effective therapies for patients with ulcerative colitis (UC), they can be costly and may not be widely available. Therefore, less expensive biosimilars have been developed and approved to treat and manage symptoms. In this new treatment landscape, UC-treatment preferences are unknown. Thus, this interim analysis aimed to characterise physician preferences for biologics for the treatment of UC in France, Germany and the UK. Methods As part of a broader chart review study, treatment preferences were also collected from participating gastroen

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Oğuz, Osman, Hilal Mercan, and F. Sinem Hocaoglu-Emre. "Biological variation of glycated albumin, glucose and albumin in healthy Turkish subjects." Turkish Journal of Biochemistry 46, no. 2 (2021): 197–203. http://dx.doi.org/10.1515/tjb-2020-0115.

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Abstract Objectives Biological variation (BV) in laboratory tests can be defined as the variation in analyte concentration over time within and between individuals. Glycated albumin (GA) is a ketoamine which is used in the short-term monitoring of diabetes. The aim of this research was to determine BV of GA, glucose, and albumin under a well-designed and standardized protocol. Methods Blood samples were collected weekly from 21 healthy subjects (10 males, 11 females) for four consecutive weeks. Samples were analyzed using enzymatic methods in duplicate. After subjected to outlier and normality

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SCRIVO, ROSSANA, ILARIA SAUZULLO, FABIO MENGONI та ін. "Mycobacterial Interferon-γ Release Variations During Longterm Treatment with Tumor Necrosis Factor Blockers: Lack of Correlation with Clinical Outcome". Journal of Rheumatology 40, № 2 (2012): 157–65. http://dx.doi.org/10.3899/jrheum.120688.

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Objective.To assess the performance of serial QuantiFeron-TB Gold In-Tube (QFT-GIT) tests in patients with rheumatic diseases during longterm systemic treatment with biologic therapy, evaluating conversions and reversions in relation to the clinical outcome.Methods.We conducted a prospective study on patients awaiting biologic agents. At baseline, they had chest radiographs, QFT-GIT tests, and tuberculin skin tests (TST); QFT-GIT was repeated at 3, 6, 12, and 18 months after onset of biologic therapy. In patients with no evidence of latent tuberculosis infection (LTBI) at baseline, TST was rep

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Capo, Alessandra, Marta Di Nicola, Matteo Auriemma, et al. "Mean platelet volume variation after biologic therapy in psoriasis and psoriatic arthritis." European Journal of Dermatology 24, no. 1 (2014): 133–35. http://dx.doi.org/10.1684/ejd.2014.2269.

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Fraser, Callum G. "Clinically Useful Limits (CUL) Criteria Best Based on Within-Subject Biologic Variation." American Journal of Clinical Pathology 92, no. 2 (1989): 256. http://dx.doi.org/10.1093/ajcp/92.2.256a.

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Braga, Federica, Dominika Szőke, Cristina Valente, and Mauro Panteghini. "Biologic variation of copper, ceruloplasmin and copper/ceruloplasmin ratio (Cu:Cp) in serum." Clinica Chimica Acta 415 (January 2013): 295–96. http://dx.doi.org/10.1016/j.cca.2012.11.007.

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Van Ness, Brian G., John C. Crowley, Christine Ramos, et al. "SNP Associations with Event Free Survival in Myeloma from Two Phase III Clinical Trials Using the Bank On A Cure Chip." Blood 108, no. 11 (2006): 131. http://dx.doi.org/10.1182/blood.v108.11.131.131.

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Abstract:

Abstract While there are certain common clinical features in myeloma, the disease shows significant heterogeneity with regard to disease progression, and responses to therapy, affecting both survival and toxicities. Heritable variations in a wide variety of genes and pathways affecting cellular functions and drug responses likely impact patient outcomes. In the Bank On A Cure (BOAC) program we have developed a custom chip that assesses 3,404 SNPs representing variations in cellular functions and pathways that may be involved in myeloma progression and response. The chip has gone through rigoro

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Saret, CJ, MJ Cangelosi, JD Chambers, JT Cohen, and PJ Neumann. "Geographic Variation In Local Medicare Coverage For Part B Biologics." Value in Health 16, no. 3 (2013): A10. http://dx.doi.org/10.1016/j.jval.2013.03.062.

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Bortfeld, Thomas, and Harald Paganetti. "The biologic relevance of daily dose variations in adaptive treatment planning." International Journal of Radiation Oncology*Biology*Physics 65, no. 3 (2006): 899–906. http://dx.doi.org/10.1016/j.ijrobp.2006.02.036.

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