Log in

Relevant bibliographies by topics / Variation (biology) / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Variation (biology).

Dissertations / Theses on the topic 'Variation (biology)'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 July 2024

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Variation (biology).'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Franks, Alexander M. "Quantifying Sources of Variation in High-throughput Biology." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17463988.

Full text

Abstract:

One of the central challenges in systems biology research is disentangling relevant and irrelevant sources of variation. While the relevant quantities are always context dependent, an important distinction can be drawn between variability due to biological processes and variability due measurement error. Biological variability includes variability between mRNA or protein abundances within a well defined condition, variability of these abundances across conditions (physiological variability), and between species or between subject variability. Technical variability includes measurement error

APA, Harvard, Vancouver, ISO, and other styles

2

Herfindal, Ivar. "Life history consequences of environmental variation along ecological gradients in northern ungulates." Doctoral thesis, Norwegian University of Science and Technology, Department of Biology, 2006. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-706.

Full text

Abstract:

<p>Temporal and spatial variation in the environment can influence the performance of individuals in wild ungulate populations. Of particular importance is an understanding of the mechanisms that shape variation in individual body mass, because several important life history traits are directly related to body mass. Body mass is one of the first traits that is influenced by environmental variation, and often the effect operates through variation in the components of the foraging niche of ungulates. In this thesis, I aim to demonstrate how measurements of environmental variation relate to varia

APA, Harvard, Vancouver, ISO, and other styles

3

Larsson, Jobs Karl. "Population Fragmentation and Genetic Variation in Grouse." Doctoral thesis, Uppsala University, Department of Ecology and Evolution, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6006.

Full text

Abstract:

<p>In this thesis the genetic variation of two grouse species, the Chinese grouse (<i>Bonasa sewersowi</i>) and the Black grouse (<i>Tetrao tetrix</i>) was examined with neutral genetic markers: microsatellites. Habitat fragmentation and isolation leads to structuring among and loss of genetic variation within populations.</p><p>The Chinese grouse in a small population in Lianhuasan nature reserve was found to have undergone a population bottleneck and as a result of isolation and possible inbreeding showed genetic impoverishment hereof.</p><p>The Black grouse populations in Europe face variou

APA, Harvard, Vancouver, ISO, and other styles

4

Jacobs, Jerry Dale. "Regulation of life history strategies with individuals in predictable and unpredictable environments /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/5169.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Allen, J. B. "Geographical variation and population biology in wild Theobroma cacao." Thesis, University of Edinburgh, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384148.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Davids, Wagied. "Causes of Substitution Frequency Variation in Pathogenic Bacteria." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4838.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Barrera, Luis A. "Towards a Systematic Approach for Characterizing Regulatory Variation." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718710.

Full text

Abstract:

A growing body of evidence suggests that genetic variants that alter gene expression are responsible for many phenotypic differences across individuals, particularly for the risk of developing common diseases. However, the molecular mechanisms that underlie the vast majority of associations between genetic variants and their phenotypes remain unknown. An important limiting factor is that genetic variants remain difficult to interpret, particularly in noncoding sequences. Developing truly systematic approaches for characterizing regulatory variants will require: (a) improved annotations for th

APA, Harvard, Vancouver, ISO, and other styles

8

Benmerzouga, Imaan A. "REGULATION OF ANTIGENIC VARIATION IN TRYPANOSOMA BRUCEI." Cleveland State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=csu1376047183.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Foulkes, Nicholas F. "Molecular biology of the human G 6-PD gene." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Wilson, David Francis. "Purposive variation in recordkeeping in the academic molecular biology laboratory." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2482/.

Full text

Abstract:

This thesis presents an investigation into the role played by laboratory records in the disciplinary discourse of academic molecular biology laboratories. The motivation behind this study stems from two areas of concern. Firstly, the laboratory record has received comparatively little attention as a linguistic genre in spite of its central role in the daily work of laboratory scientists. Secondly, laboratory records have become a focus for technologically driven change through the advent of computing systems that aim to support a transition away from the traditional paper-based approach toward

APA, Harvard, Vancouver, ISO, and other styles

11

Stevens, D. P. "Studies of variation and reproductive biology in Saxifraga granulata L." Thesis, University of Newcastle Upon Tyne, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370163.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Kenyon, David Michael. "The biology and pathogenic variation of Erysiphe species on rhododendron." Thesis, University of Strathclyde, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252052.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Patil, Sonali A. "Single cell interferon beta response variation with virus infection." Thesis, Icahn School of Medicine at Mount Sinai, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3617973.

Full text

Abstract:

<p> Viral infection and the subsequent immune responses such as the expression of interferon beta (<i>ifnb1</i>) show extreme levels of cell to cell variability. A fraction of cells get infected and a fraction of infected cells induce an <i>ifnb1</i> response. These responding cells then signal to coordinate appropriate immune responses required to clear infection. The mechanism of propagation of this response at the single cell level is critical to generate an appropriate defense against the virus, yet is incompletely understood. </p><p> Interesting work on cell to cell variability has be

APA, Harvard, Vancouver, ISO, and other styles

14

Postuma, Ronald B. "Seasonal variation in risk of Parkinson's disease." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=99199.

Full text

Abstract:

Parkinson's disease (PD) is a common neurodegenerative condition characterized by progressive motor, speech, swallowing, and gait difficulties. Risk factors for PD include male sex, pesticide exposure, head trauma, and rural living, but these account for only a small amount of the variation in risk. Recent studies suggest that for many neurological diseases, people born at a certain time of year are at higher risk of developing the disease. Small-scale studies have also suggested that persons born in the spring may be at higher risk of developing PD late in life. We examined the birth dates of

APA, Harvard, Vancouver, ISO, and other styles

15

Cantonwine, Emily Gayle. "Phenylheptatriyne variation in bidens alba var. radiata leaves." FIU Digital Commons, 1999. http://digitalcommons.fiu.edu/etd/2031.

Full text

Abstract:

Variation of phenylheptatriyne (PHT) concentrations in leaves of Bidens alba (Linn.) var. radiata (Schultz-Bip.) was investigated across it's Florida range, throughout the year and in response to photoenvironment. Natural surveys of PHT concentrations in B. alba leaves were done at 13 sites in Florida and three sites throughout the year. PHT concentrations were significantly different between populations (p<0.001) but showed little relationship with latitude (R2 =0.024) and none with longitude. Concentrations in leaves fluctuated throughout the year (p<0.001). They were highest in October, fol

APA, Harvard, Vancouver, ISO, and other styles

16

Blackman, Benjamin K. "Evolutionary genetics of flowering time regulation and variation in Helianthus." [Bloomington, Ind.] : Indiana University, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3373495.

Full text

Abstract:

Thesis (Ph.D.)--Indiana University, Dept. of Biology 2009.<br>Title from home page (viewed on Jul 8, 2010). Source: Dissertation Abstracts International, Volume: 70-10, Section: B, page: 5957. Advisers: Loren H. Rieseberg; Scott D. Michaels.

APA, Harvard, Vancouver, ISO, and other styles

17

Obaid, Jian. "What is known about genetic variation among Baltic Sea blue mussels and the promise of proteomics. A literature review." Thesis, Södertörn University College, School of Life Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-2701.

Full text

Abstract:

<p>The Baltic Sea is an evolutionary young sea that have developed a low salinity in its water from the fresh water that flows from the north and saltwater that flows from the south of the sea. The low salinity is too low for many marine organisms and too high for many freshwater organisms. Species like the blue mussel, which have adapted to the low salinity, may have developed different protein expression as a result. To study which protein that have been expressed in the organism proteome analysis is often used. 2-dimensional electrophoresis may be the only method that can do this kind of an

APA, Harvard, Vancouver, ISO, and other styles

18

PANDYA, UNNATI. "Trypanosoma Brucei Telomere Functions In Antigenic Variation." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1406241248.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Scheper, Reiny W. A. "Studies on the biology and genetic variation of phomopsis on grapevine /." Title page, contents and abstract only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phs325.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Pool, P. A. "Variation, reproductive biology and yielding behaviour in cloves (Syzygium aromaticum L.)." Thesis, University of Reading, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379309.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Peters, Derek Tilghman. "Isogenic Human Pluripotent Stem Cell Models of Cardiovascular Disease-Associated Genetic Variation." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493401.

Full text

Abstract:

A complex interplay of genetic and environmental factors underlies the development of common human diseases such as cardiovascular disease. Despite widespread use of existing medications, coronary heart disease (CHD), including myocardial infarction (MI), remains a significant cause of morbidity and mortality worldwide. The results of recent human genetic studies have provided unprecedented opportunities to elucidate the genes and molecular pathways that underlie CHD and risk factors like plasma lipid concentrations. Translating these findings into mechanistic insight promises to improve our u

APA, Harvard, Vancouver, ISO, and other styles

22

Li, Xiang. "STRESS-INDUCED GENETIC CHANGE IN FLAX REVEALS GENOME VARIATION MECHANISM." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1565964370435691.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Ratnappan, Ramesh. "Analyses of adaptive evolution and recombination rate variation in Drosophila." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/3517.

Full text

Abstract:

The neutral theory of molecular evolution provides a framework to understand the molecular basis of evolutionary change. The fundamental principle of the neutral theory is that the majority of mutations observed within populations as well as between species is neutral. More importantly, the theoretical framework that the neutral theory provides not only includes mutation and random genetic drift but also two other important parameters in evolution: selection and recombination. Molecular evolutionary analyses allow us to estimate the magnitude and consequences of these parameters in natural pop

APA, Harvard, Vancouver, ISO, and other styles

24

Parsley, Meghan. "Adaptive Variation in Tiger Salamander Populations." TopSCHOLAR®, 2017. https://digitalcommons.wku.edu/theses/2056.

Full text

Abstract:

Amphibians face an unknown future in a time of rapid environmental change due to global climate perturbations. Since amphibians are perceived to be indicators of ecosystem health, understanding the causes of their declines can improve our perception of threats to other species. Molecular techniques have allowed us to explore how environmental change affects genetic variation and to predict evolutionary adaptive potential of amphibian populations. The identification of populations with the greatest potential to respond to changing environmental variables may be an important conservation strateg

APA, Harvard, Vancouver, ISO, and other styles

25

Danielson-Francois, Anne. "Variation in Tetragnathid spermathecal structures and sperm competition with descriptions of natural history." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/279954.

Full text

Abstract:

The study of variation in arachnid genitalic structures has contributed to the fields of systematics and sexual selection. Simon (1892--1903) in his Histoire Naturelle des Araignees first divided the ecribellate higher spiders into two groups, the Haplogynae and Entelegynae, using reproductive morphology. Spider genitalia have been used as a taxonomic tool for distinguishing between taxa because of their species-specific morphological variation. Variation in spider genitalic morphology has inspired evolutionary biologists to test mechanisms of sexual selection by which the variation could evol

APA, Harvard, Vancouver, ISO, and other styles

26

Herron, Jon C. "Genetic variation, thermal sensitivity, and thermal acclimation in Volvox aureus and Volvox globator /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/5115.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Dolphin, Kimberly E. "Variation in mating preferences and behaviors in Drosophila melanogaster." Thesis, California State University, Long Beach, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1585517.

Full text

Abstract:

<p> I found that in inbred females <i>D. melanogaster,</i> physical condition plays a major role in the amount of polyandry. In some systems there is evidence that the ability to self assess allows inbred females to vary their reproductive behavior to increase promiscuity. I predicted that this may be true in <i>Drosophila melanogaster</i> females, but we found that inbred females behaved less promiscuously in three proxies than outbred females. Inbred females mated with fewer total males, fewer different males, and had longer copulation latency than their outbred conspecifics. However, ma

APA, Harvard, Vancouver, ISO, and other styles

28

Lewis, Paul Ollin. "Allozyme variation and evolution in Polygonella (Polygonaceae)." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1239622655.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Mal, Tarun K. "Population biology and floral variation in Lythrum salicaria, a heterostylous colonizing weed." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1996. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ30286.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Einarsson, Elin. "Comparative Cell Biology in Diplomonads." Doctoral thesis, Uppsala universitet, Institutionen för cell- och molekylärbiologi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-264541.

Full text

Abstract:

The diplomonads are a diverse group of eukaryotic flagellates found in microaerophilic and anaerobic environments. The most studied diplomonad is the intestinal parasite Giardia intestinalis, which infects a variety of mammals and cause diarrheal disease. Less is known about Spironucleus salmonicida, a parasite of salmonid fish, known to cause systemic infections with high mortality. We created a transfection system for S. salmonicida to study cellular functions and virulence in detail (Paper I). The system was applied to explore the mitochondrion-related organelle (MRO) in S. salmonicida. We

APA, Harvard, Vancouver, ISO, and other styles

31

Carrara, Susan. "Genetic variation among cultivated selections of mamey sapote (Pouteria spp. [Sapotaceae])." FIU Digital Commons, 2004. http://digitalcommons.fiu.edu/etd/2054.

Full text

Abstract:

Mamey sapote [Pouteria spp., Sapotaceae] is a tree fruit of economic and cultural importance in Central America, Mexico, and the Caribbean islands. It contributes greatly to local economies, habitats, and human nutrition. This study is among the first to analyze genetic variability among cultivated selections of mamey sapote. The Amplified Fragment Length Polymorphism (AFLP) molecular technique was used to estimate levels of genetic diversity and similarity between individual specimens in the germplasm collections of Fairchild Tropical Botanic Garden and University of Florida. The study found

APA, Harvard, Vancouver, ISO, and other styles

32

Sosnoskie, Lynn Marie. "Investigations in weed biology studies at the plant, population, and community levels /." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1102976937.

Full text

Abstract:

Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xx, 147 p.; also includes graphics (some col.) Includes bibliographical references (p. 137-147).

APA, Harvard, Vancouver, ISO, and other styles

33

Dankwa, Selasi. "Sialic acid variation as a determinant of Plasmodium invasion of erythrocytes in malaria infection." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467188.

Full text

Abstract:

Sialic acids are acidic sugars that terminate glycan chains on proteins or lipids on vertebrate cell surfaces. They vary greatly in structure, presentation and amount, all of which are important physiologically, but can also impact the tissue and host tropism of diverse pathogens. Parasites of the genus Plasmodium cause malaria, a disease characterized by a cyclical process of parasite invasion of host erythrocytes, growth and replication and fresh invasion of new erythrocytes. During erythrocyte invasion – an event central to malaria pathogenesis – proteins on the surface of the parasite, kn

APA, Harvard, Vancouver, ISO, and other styles

34

Kitson, Sarah R. "Malaclemys terrapin Hatchlings: Variation in Seasonal Emergence." Ohio University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1479156414322192.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Anderson, Jeffrey K. "Systematic implications of isozyme number variation in Tribe Brassiceae (Brassicaceae)." Thesis, University of Ottawa (Canada), 1995. http://hdl.handle.net/10393/9643.

Full text

Abstract:

Tribe Brassiceae (haploid chromosome number, n=6$-$75) is generally recognized as one of the few natural (monophyletic) groups in the Brassicaceae. Recent molecular analyses, however, have questioned the validity of this subtribal classification and have proposed new generic and subtribal circumscriptions. The present study examined isozyme number, which is usually highly conserved in diploid plants, in order to assess the evolution of chromosome number and systematic relationships in the tribe. Ten enzyme systems were surveyed for 108 species in 35 genera of tribe Brassiceae and for eleven sp

APA, Harvard, Vancouver, ISO, and other styles

36

Lee, Peter Daniel. "Building a model for mapping genetic variation affecting gene expression." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85931.

Full text

Abstract:

The majority of genetic traits including most common diseases are believed to be multigenic and arise both from variations in coding sequences as well as from regulatory polymorphisms. Genome-wide approaches are needed to develop models for understanding this complexity. This thesis develops approaches for studying genetic variation affecting gene expression on a genome-wide scale. This included development of experimental design principles and analytical methods for microarray data. These principles were then applied to characterize differences between commonly-used A/J and C57BL/6J in

APA, Harvard, Vancouver, ISO, and other styles

37

Al-Sulaimani, Maha Saleh. "Genetic variation in the FMO2 gene : evolution & functional consequences." Thesis, Queen Mary, University of London, 2011. http://qmro.qmul.ac.uk/xmlui/handle/123456789/2324.

Full text

Abstract:

Flavin-containing monooxygenase 2 (FMO2) is involved in the metabolism of xenobiotics, including therapeutic drugs. FMO2 exists in two forms: a functional and a non-functional form. The functional allele is found only in Africa and individuals of recent African origin. The aims of the project were to determine the frequency of functional FMO2 in Africa and obtain insights into the evolutionary history of the FMO2 gene. Six hundred and eighty nine samples from nine African population groups were genotyped for six high-frequency SNPs, and the genetic diversity within FMO2 was characterized by se

APA, Harvard, Vancouver, ISO, and other styles

38

Lomelin, David. "Using human genetic variation to predict functional elements in non-coding genomic regions." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3390057.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Jordan, Daniel Michael. "Predicting the Effects of Missense Variation on Protein Structure, Function, and Evolution." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17464216.

Full text

Abstract:

Estimating the effects of missense mutations is a problem with many important applications in a variety of fields, including medical genetics, evolutionary theory, population genetics, and protein structure and design. Many popular methods exist to solve this problem, the most widely used of which are PolyPhen-2 and SIFT. These methods, along with most other popular methods, rely on multiple sequence alignments of orthologous protein sequences. Based on the amino acids observed in each column of the alignment, they produce a profile describing how tolerated each amino acid is at each position.

APA, Harvard, Vancouver, ISO, and other styles

40

Zuravnsky, Kristin Nicole. "Understanding the roles of polyploidy and the environment on nordihydroguaiaretic acid variation in Larrea tridentata." Thesis, Salisbury University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1525307.

Full text

Abstract:

<p> Nordihydroguaiaretic acid (NDGA) is the principal compound in the resinous leaf coating of <i>Larrea tridentata</i> (creosote bush), the dominant shrub of North American deserts. <i>L. tridentata</i> exists as three polyploid races: diploid (2X = 26), tetraploid (4X = 52), and hexaploid (6X = 78). The distributions of these ploidy levels are strongly associated with the three major deserts of the region where diploids primarily reside in the cooler, wetter Chihuahuan desert, tetraploids in the Sonoran desert, and hexaploids in the hot, dry Mojave desert. NDGA is a secondary metabolite of c

APA, Harvard, Vancouver, ISO, and other styles

41

Cosner, Mary Elizabeth. "Phylogenetic and molecular evolutionary studies of chloroplast DNA variation in the campanulaceae /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487847761306203.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Dimsoski, Pero. "Variation in microsatellite loci and trait differences in Yorkshire and Large White /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487935958845124.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Morisak, Kelli M. "Variation of Pseudogymnoascus destructans Spore Loads and Risk of Human Vectored Transport." University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1511983700318656.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Cropp, Cheryl D. "Genetic variation in drug transporters in ethnic populations." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3339183.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Samocha, Kaitlin E. "Modeling Rare Protein-Coding Variation to Identify Mutation-Intolerant Genes With Application to Disease." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493508.

Full text

Abstract:

Sequencing exomes—the 1% of the genome that codes for proteins—has increased the rate at which the genetic basis of a patient’s disease is determined. Unfortunately, when a patient does not carry a well-established pathogenic variant, it is extremely challenging to establish which of the tens of thousands of variants identified in that individual is contributing to their disease. In these situations, variants must be prioritized to make further investigation more manageable. In this thesis, we have focused on creating statistical frameworks and models to aid in the interpretation of rare varia

APA, Harvard, Vancouver, ISO, and other styles

46

Coon, Keith Darren. "Genetic variation of maternal and paternal lineages within the Havasupai Indians of northern Arizona." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/284314.

Full text

Abstract:

The Havasupai Indians are a small (∼600 members), Yuman-speaking population that resides on a reservation in the Grand Canyon region of northern Arizona. Due to their location and cultural practices, they are subjected to extreme geographic and reproductive isolation. Additionally, an influenza epidemic at the turn of the century decreased the reproducing population to 43 females and 42 males. These observations suggest that the Havasupai should contain less genetic diversity than other Native American populations. They are also disproportionately affected by disease, having the third largest

APA, Harvard, Vancouver, ISO, and other styles

47

Anders, Constance. "Morphological, Molecular, and Biogeographical Variation within the Imperiled Virginia Spiraea." TopSCHOLAR®, 2000. http://digitalcommons.wku.edu/theses/709.

Full text

Abstract:

Spiraea virginiana Britton is a rare federally listed rhizomatous shrub endemic to the southern Blue Ridge and Appalachian Plateau physiographic provinces. Populations of S. virginiana are found restricted to scoured sections of high gradient streams within the Ohio River drainage. Present evidence indicates the species is reproducing asexually, most probably through the deposition of rhizomes from upstream populations forming new downstream ramets. Phenotypic variation was examined through a morphometric evaluation of 25 leaf measurements and analyzed using Principal Components Analysis (PCA)

APA, Harvard, Vancouver, ISO, and other styles

48

Barker, Carl. "Ecological, genetic and metabolic variation in populations of Tilia cordata." Thesis, Edge Hill University, 2017. http://repository.edgehill.ac.uk/10392/.

Full text

Abstract:

Predicting the responses of tree species to rapid environmental change requires an understanding of their ecology, reproductive strategy, population connectivity and levels of adaptive variation. This project examines these aspects for an understudied UK native tree genus Tilia L. Comparison of edaphic and physiographic variables indicated that Tilia cordata Mill. is more generalist than T. platyphyllos Scop., as well as preferring locations with higher potential incident solar radiation and greater levels of organic carbon content. Examination of fine-scale spatial genetic structure indicates

APA, Harvard, Vancouver, ISO, and other styles

49

Desai, Kinjal. "Characterizing the impact of single nucleotide variation in breast cancer." Thesis, Dartmouth College, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10144817.

Full text

Abstract:

<p> Genome sequencing technology has enabled the identification of genetic variants that are linked with cancer phenotypes, whether these are somatically acquired mutations or common inherited single nucleotide polymorphisms (SNPs). Whereas coding variants have been reported to disrupt protein function to promote cancer, most variants map to noncoding regions, with no known function. Recently, much effort has gone into annotating the human noncoding genome, enabling the characterization of the functional basis of noncoding SNPs. As an example of functional impact, breast cancer (BrCa) risk-ass

APA, Harvard, Vancouver, ISO, and other styles

50

San, Martin Elena. "Latitudinal variation in plankton size spectra along the Atlantic Ocean." Thesis, University of Southampton, 2005. https://eprints.soton.ac.uk/41351/.

Full text

Abstract:

Abundance-size distributions of organisms within a community reflect fundamental properties underlying population dynamics. These include characteristics such as predator to prey biomass ratios, given the relationships that exist between body mass and metabolic activity, and between body mass and the ecological regulation of population density. In this way, plankton size has an important role in structuring the rates and pathways of material transfer in the marine pelagic food web, and consequently the oceanic carbon cycle. The transfer of energy between trophic levels can be inferred from reg

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!