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1

Brown, Marena Dessette. "Sickle cell-endothelial interactions : modulation of cell adhesion molecule expression." Diss., Georgia Institute of Technology, 1995. http://hdl.handle.net/1853/11306.

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Cooke, Vesselina G. "Role of Junctional Adhesion Molecule-A in vascular biology." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 147 p, 2008. http://proquest.umi.com/pqdweb?did=1495945061&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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3

Alapati, Anuja. "Small Organic Molecule Inhibition of Tumor Necrosis Factor-a Induced Vascular Cell Adhesion Molecule-1 Expression by Endothelial Cells." Ohio University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1375177527.

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4

Wu, Tao. "Structure-function analysis of vascular tethering molecules using atomic force microscope." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/31844.

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Thesis (Ph.D)--Mechanical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Zhu, Cheng; Committee Member: Barry, Bridgette; Committee Member: Boyan, Barbara; Committee Member: McEver, Rodger; Committee Member: McIntire, Larry. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Ramrakha, Punit Satyavrat. "Strategies to modulate leukocyte adherence to endothelium : inhibition of vascular cell adhesion molecule expression." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402448.

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6

Koßmann, Eugen Franz Josef [Verfasser]. "Vascular Cell Adhesion Molecule-1 (VCAM-1) modulates plasticity of human melanoma cells / Eugen Franz Josef Koßmann." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://d-nb.info/1233008927/34.

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7

Fukiage, Kenichi. "Expression of vascular cell adhesion molecule-1 indicates the differentiation potential of human bone marrow stromal cells." Kyoto University, 2010. http://hdl.handle.net/2433/120604.

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8

Mulgrew, Scott. "Fatty acid regulation of adhesion molecule expression in human vascular cells." Thesis, Robert Gordon University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526063.

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9

Gandhi, Neha Sureshchandra. "Molecular modelling of platelet endothelial cell adhesion molecule 1 and its interaction with glycosaminoglycans." Thesis, Curtin University, 2007. http://hdl.handle.net/20.500.11937/1513.

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The Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) has many functions including its roles in leukocyte extravasation as part of the inflammatory response, and in the maintenance of vascular integrity through its contribution to endothelial cell-cell adhesion. Various heterophilic ligands of PECAM-1 have been proposed. The possible interaction of PECAM-1 with glycosaminoglycans (GAGs) is the focus of this thesis. The three dimensional structure of the extracellular immunoglobulin (Ig)-domains of PECAM-1 was constructed using homology modelling and threading methods. Potential heparin/h
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10

Amos, Amanda Owings. "Regulation of cytokine-induced adhesion molecule expression and sickle erythrocyte adhesion to microvascular endothelial cells by intracellular adenosine 3',5'-cyclic monophosphate and nitric oxide." Diss., Available online, Georgia Institute of Technology, 2006, 2006. http://etd.gatech.edu/theses/available/etd-04052006-104355/.

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Thesis (Ph. D.)--Chemical and Biomolecular Engineering, Georgia Institute of Technology, 2006.<br>Dr. Peter A. Lane, Committee Member ; Dr. Larry V. McIntire, Committee Member ; Dr. Ronald W. Rousseau, Committee Member ; Dr. James R. Eckman, Committee Member ; Dr. Timothy M. Wick, Committee Chair.
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Couffinhal, Thierry. "Etude de l'expression des E-sélectines, d'intercellular adhesion molecule-1 (ICAM-1) et du vascular cell adhesion molecule-1 (VCAM-1) dans les cellules de la paroi artérielle." Bordeaux 2, 1994. http://www.theses.fr/1994BOR28285.

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Dans l'athérosclérose, la cellule endothéliale (CE) activée joue un rôle central dans le recrutement monocytaire pariétal. Parallèlement, le recrutement macrophagique au sein des plaques joue un rôle important dans l'activation des CE et des cellules musculaires lisses (CML). Les travaux de la littérature ont permis d'individualiser, in vitro, le rôle des protéines d'adhésion endothéliales E-selectines, ICAM-1 et VCAM-1 dans l'adhésion des monocytes et des T lymphocytes. Cependant, peu de données étaient disponibles, in vivo, dans l'athérosclérose. Notre premier travail s'est attaché à définir
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Deosarkar, Sudhir P. "Development of Novel Therapeutic and Diagnostic Approaches for Atherosclerosis." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1268371885.

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13

Duplàa, Cécile. "Etude de la régulation d'intercellular Adhesion Molécule-1 (ICAM-1) et de Vascular Cell Adhesion Molécule-1 (VCAM-1) dans les cellules musculaires lisses en culture." Bordeaux 2, 1994. http://www.theses.fr/1994BOR28281.

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Le recrutement des cellules musculaires lisses (CML) dans l'intima représente un événement clé dans les pathologies artérielles. La compréhension des mécanismes régulant les capacités migratoires et synthétiques des CML, c'est à dire l'état de différenciation, est déterminante dans la perspective du contrôle du développement ou de l'arrêt du processus d'hyperplasie intimale. Certaines protéines membranaires (les intégrines ou les molécules d'adhésion) en permettant les interactions cellule/cellule ou cellule/matrice extracellulaire sont des acteurs du changement de phénotype de la CML. Nous av
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14

Chang, Chao-Hui. "Haematopoietic stem/progenitor cell interactions with the bone marrow vascular niche." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:452da334-bd4e-45c7-a7bd-fc8767d1239c.

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Umbilical cord blood (UCB) is used as a source of haematopoietic stem cells (HSCs) for transplantation but shows defective homing to the bone marrow niche and delayed haematological reconstitution. Following transplantation, HSCs will home to the bone marrow in response to the CXCL12 chemokine, adhere to the bone marrow sinusoidal endothelial cells and then migrate into and lodge in bone marrow niches. In addition to CXCR4, a variety of molecules have been described as being important in these processes. In this laboratory, junctional adhesion molecule-A (JAM-A) was shown to be expressed on hu
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Liang, Jacky. "The Effects of Acute Running Induced Neuronal Activation on Cerebral GLUT1 and Vascular Plasticity." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20396.

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Morphologic and metabolic change is a known property of the adult brain. A number of behavioural tasks alter local cerebral blood flow and glucose utilisation. The expression of the glucose transporter 1 (GLUT1), which allows the entry of glucose to the brain, also has been shown to change in response to long-lasting neuronal activation. However, little is known about the effect of acute neuronal activation on GLUT1 expression. Using immunohistochemistry and Western blot, we investigated cerebral GLUT1 expression and vasculature density in mice undergoing a 48-hour voluntary wheel running peri
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Strindhall, Jan. "Innate immune response in human endothelial cells : characterization and regulation of E-selectin, ICAM-I and cytokine expression and the role of Staphylococcus aureus /." Linköping : Univ, 2003. http://www.bibl.liu.se/liupubl/disp/disp2003/med804s.pdf.

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Frechou, Magalie. "Identification de nouveaux agents de contraste pour la détection par IRM à haut champ de biomarqueurs dans l'ischémie cérébrale." Thesis, Paris 5, 2012. http://www.theses.fr/2012PA05P602.

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Ce travail de thèse s'inscrit dans le cadre d'une collaboration avec le groupe Guerbet. Il visait à caractériser la lésion qui fait suite à un accident vasculaire cérébral (AVC) ischémique en imagerie par résonance magnétique (IRM) grâce à des agents de contraste novateurs. Guerbet et leurs collaborateurs ont développés des USPIO ciblés (ultrasmall superparamagnetic iron oxide), particules de fer couplées à des peptides reconnaissant spécifiquement un biomarqueur. Dans un modèle d’ischémie cérébrale avec reperfusion réalisé chez la souris, nous avons recherché la capacité de ces agents à carac
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Dourado, Letícia Barbosa Kawano. "Ativação endotelial na granulomatose com poliangeíte (granulomatose de Wegener)." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-11052015-141231/.

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INTRODUÇÃO: Eventos vasculares e imunológicos são centrais na patogênese da granulomatose com poliangeíte (GPA). Moléculas de adesão celular tem papel fundamental no recrutamento de células inflamatórias do sangue para os tecidos. Diferentes leitos vasculares apresentam particularidades na expressão de moléculas de adesão celular explicando talvez parte da especificidade da GPA por determinados órgãos. A elevação no nível sérico de moléculas de adesão celular e aumento da expressão destas em amostras de biópsia renal já foram demonstrados em pacientes com vasculite ANCA associada. No entanto,
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Kölbeck, Karl-Gustav. "Nasal and bronchial airway reactivity in allergic and non allergic airway inflammation /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-428-3/.

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Soares, Andressa Heimbecher. "Hipogonadismo associado à obesidade: efeitos do tratamento com citrato de clomifeno." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-13062018-074535/.

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INTRODUÇÃO: A obesidade é uma das causas de hipogonadismo (HG) secundário no homem. A terapia de reposição padrão de testosterona (TRT) é associada à melhora dos parâmetros metabólicos, mas pode levar à infertilidade. Apenas recentemente indicou-se que não há novas evidências nível 1 para apoiar uma conexão definitiva entre TRT e eventos cardiovasculares (CV). OBJETIVO: Avaliar os efeitos do Citrato de Clomifeno (CC) em homens jovens com hipogonadismo associado à obesidade diagnosticado por testosterona total (TT) <= 300 ng/dL em duas ocasiões, sintomas positivos no questionário ADAM, hormônio
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21

Sandlund, Johanna. "Angiogenesis in human renal cell carcinoma : hypoxia, vascularity and prognosis." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1331.

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Вернигородський, В. С., Н. М. Фетісова, М. В. Вернигородська, Р. В. Валентьєва та О. В. Мальченко. "Зв'язок рівнів молекули адгезії судинних клітин svcam-1 з порушенням ліпідного обміну у хворих на гіпотиреоз". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/63624.

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Гіпотиреоз – захворювання, що характеризується поліморфністю клінічних симптомів. На тлі гіпотиреозу зазнають змін всі без винятку органи і системи. Доведено, що дефіцит тиреоїдних гормонів спричиняє суттєві порушення ліпідного обміну, що зумовлюють формування проатерогенних змін, ендотеліальної дисфункції та прогресування ішемічної хвороби серця навіть за умов субклінічного гіпотиреозу [1; 2; 3]. Водночас питання щодо поширеності та особливостей дисліпідемій у хворих з різними видами гіпотиреозу досі залишається відкритим. У численних наукових дослідженнях доведено, що гіпотиреоїдний
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Zhao, Bo. "Local mRNA expression of vascular cell adhesion molecule-1 (VCAM-1), macrophage colony-stimulating factor (MCSF-1), and its receptor, c-fms, on rabbit heart valves in the early phase after atrioventricular valve surgery and Staphylococcus aureus bacteremia." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972046437.

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Zago, Alexandre do Canto. "Importância da interação entre a integrina Mac-1 leucócitos e a glicoproteína Ib alfa das plaquetas para o recrutamento de leucócitos pelas plaquetas e para a resposta inflamatória à lesão vascular." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-11032008-140622/.

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INTRODUÇÃO: A interação entre leucócitos e plaquetas é fundamental para o início e a progressão da reestenose e da aterosclerose. Recentemente foi evidenciado em estudos in vitro que a integrina Mac-1 dos leucócitos se liga à glicoproteína Ibalfa (GP Ibalfa) das plaquetas e que esta interação possui uma função central na firme adesão e transmigração de leucócitos em locais de deposição de plaquetas. Entretanto, não há estudos in vivo que avaliam a importância da interação entre a integrina Mac-1 dos leucócitos e a GP Ibalfa das plaquetas (alfaMbeta2-GP Ibalfa) em modelo experimental de lesão v
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Jakobsson, Emma. "Structural Studies of Echinococcus granulosus Fatty-acid-binding Protein 1 and Human Semicarbazide-sensitive Amine Oxidase." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis: Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5884.

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Maghzal, Nadim. "The epithelial cell adhesion molecule (EpCAM) regulates cell motility and cell-cell adhesion by inhibiting PKC signaling." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114215.

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Tissue cohesion is achieved in part by a large family of plasma membrane-bound cell adhesion molecules (CAMs). During morphogenesis, CAM-mediated interactions provide adhesive forces required for cells to aggregate and form tissues. CAM-mediated adhesions in developing cells are highly dynamic, which provides the fluidity required for cellular movements that drive morphogenesis. Xenopus laevis gastrulation is an established model to study morphogenetic movements. During this phase of development, the mesoderm moves inside the embryo through involution, and migrates along the inner surface of t
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Tian, Li. "ICAM-5 (telencephalin) : a novel cell adhesion molecule." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/laa/biola/vk/tian/.

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Miyahara, Ryo. "Expression of neural cell adhesion molecules(polysialated form of neural cell adhesion molecule and L1-cell adhesion molecule)on resected small cell lung cancer specimens : in relation to proliferation state." Kyoto University, 2001. http://hdl.handle.net/2433/150163.

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Ghosh, Ananya. "Developmental expression pattern of junctional adhesion molecule-C and correlation of its expression in junctional adhesion molecule-A null mice." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 117 p, 2008. http://proquest.umi.com/pqdweb?did=1654488391&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Leung, Yu Hing Nelly. "Carcinoembryonic antigen cell adhesion molecule 1: cancer and metabolic regulation." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18740.

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Carcinoembryonic antigen cell adhesion molecule 1, CEACAM1, is a glycoprotein and a member of the CEA (carcinoembryonic antigen) family of genes. It is expressed on the surface of epithelial, endothelial, and hematopoietic cells, within the gastrointestinal tract, reproductive organs, liver, lungs and kidney. CEACAM1 plays a role in inhibiting the immune response, in cell adhesion, in insulin clearance, in cellular apoptosis and proliferation, in angiogenesis, and functions as a tumor suppressor. In humans, CEACAM1 is dysregulated and often lower in hyperplastic lesions than in normal tissue
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Takemoto, Naohiro. "Small-Molecule-Induced Clustering of Heparan Sulfate Promotes Cell Adhesion." Kyoto University, 2014. http://hdl.handle.net/2433/193544.

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Dwivedi, Amrita. "Regulation of cell adhesion molecule expression in the endothelial cell line EA.hy 926." Thesis, Oxford Brookes University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325504.

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羅慧詩 and Wai-sze Law. "Conditional knockout of neural cell adhesion molecule L1 in mouse brain." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B42575266.

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Ustaogla, Pinar. "Alternative splicing regulation of Drosophila Down Syndrome Cell Adhesion Molecule gene." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6693/.

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This thesis intends to elucidate the mechanisms regulating DSCAM (Down Syndrome Cell Adhesion Molecule) alternative splicing. This gene contains 115 exons of which 95 exons are mutually exclusively spliced. Thus, it can generate 38,016 different MRNA isoforms.
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Yamazoe, Sayumi. "A Dumbbell-Shaped Small Molecule that Promotes Cell Adhesion and Growth." Kyoto University, 2010. http://hdl.handle.net/2433/120539.

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Law, Wai-sze. "Conditional knockout of neural cell adhesion molecule L1 in mouse brain." Click to view the E-thesis via HKUTO, 2000. http://sunzi.lib.hku.hk/hkuto/record/B42575266.

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Carpenito, Carmine. "Expression and functional analysis of murine intercellular adhesion molecule 1 (ICAM-1)." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/28939.

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Cell adhesion molecules enhance Interactions between adjacent cells In order to mediate a large variety of functions of the Immune system. An antibody against the murine lymphocyte surface antigen MALA-2 has previously been shown to Inhibit mixed lymphocyte response. A λgt10 cDNA library from NS-1 cells was screened and a cDNA clone, K3-1.1, was previously isolated. It had significant homology to the human ICAM-1 gene. This thesis covers the isolation of a second cDNA clone, K4-1.1, and its comparison to K3-1.1 In terms of expression, function and distribution. The two clones are identical in
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Jannie, Karry Marie. "Activated leukocyte cell adhesion molecule (ALCAM) regulation of tumor cell behavior and neuronal targeting." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/2901.

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Numerous events during development require the tightly controlled and regulated interaction of cells - from gastrulation in the early embryo to axonal pathfinding and remodeling of synaptic networks. Each of these events is dependent upon signals generated by cell-cell interactions, which are in turn specified by a diverse number of cell adhesion molecules. Many families of cell adhesion molecules have been described, and these fall into the broad categories of cadherins, immunoglobulin superfamily (IgSF) members, selectin
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Chon, John H. "Mediation of vascular smooth muscle cell adhesion and migration by cell surface heparan sulfate glycosaminoglycans." Diss., Georgia Institute of Technology, 1999. http://hdl.handle.net/1853/11315.

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Xie, Lixia. "Effects of salvianolic acid B against apoptosis and adhesion molecules expression in the vascular endothelial cells." HKBU Institutional Repository, 2009. http://repository.hkbu.edu.hk/etd_ra/1082.

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Klompstra, Diana. "Determining the role of the cell adhesion molecule E-cadherin in contact-mediated cell polarization." Thesis, New York University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10139556.

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<p> Early embryonic cells in many species polarize radially by distinguishing their contacted and contact-free surfaces. Radial polarization is a critical patterning event driven by cell-cell contact and is required for developmental processes, such as the first differentiation event in the early mammalian embryo. The homophilic adhesion protein E-cadherin is required for contact-induced polarity in many cells. However, it is not clear whether E-cadherin functions instructively as a spatial cue, or permissively by ensuring adequate adhesion so that cells can sense other contact signals. In <i>
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Burns, James Adam. "Cell adhesion molecule mechanisms for polymorphonuclear leukocyte (PMNL) recruitment to lung inflammation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0009/MQ60670.pdf.

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Asimakopoulos, George. "Effects of aprotinin on adhesion molecule expression and leucocyte-endolethial cell interaction." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412900.

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Houri, Nadia. "Proteolytic processing of the cell adhesion molecule coxsackievirus and adenovirus receptor (CAR)." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121116.

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The Coxsackievirus and Adenovirus Receptor (CAR) is a cell adhesion molecule involved in various functions including neuronal and heart development, contribution to epithelial cell tight junction integrity, and suppression of glioma migration and invasion. Proteolysis of cell adhesion molecules, and a wide variety of other proteins, serves as a mechanism for protein turnover and may also have consequences on cellular signaling. Proteolysis by metalloproteases such A Disintegrin and Metalloprotease (ADAM) family members results in ectodomain shedding of substrates, while the presenilin/gamma-se
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Bowman, Kate Alexandra. "Functional influence of VASE insertion on neural cell adhesion molecule homophilic binding." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6424.

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Neural cell adhesion molecule (NCAM) is a transmembrane, homophilic binding protein which has important roles in cellular migration, nervous system development, learning and memory. NCAM is estimated to have at least 27 different isoforms and the functional significance of one alternatively spliced isoform, called the variable alternatively spliced exon (NCAM-VASE) is the subject of this research. NCAM-VASE differs from NCAM by the insertion of an extra ten amino acids into the fourth immunoglobulin domain. This converts NCAM function from a promoter of axonal outgrowth to an inhibitor. NCAM-V
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Elshazly, Tarek Hassan. "Characterization of PVA hydrogels with regards to vascular graft development." Thesis, Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-04082004-092432/unrestricted/elshazly%5Ftarek%5Fh%5F200405%5Fmast.pdf.

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Thesis (M.S.)--Mechanical Engineering, Georgia Institute of Technology, 2004.<br>Dr. David Ku, Committee Chair ; Dr. Raymond Vito, Committee Member ; Dr. Alexander Rachev, Committee Member. Includes bibliographical references (leaves 103-106).
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Malleske, Daniel T. "Maintaining Neutrophils at Low Temperature During in Vitro Manipulation Improves Accuracy of Cell Adhesion Molecule Analysis." Youngstown State University / OhioLINK, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=ysu999634332.

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Ismail, Hodan. "Vascular endothelial growth factor and angiopoietin-1 regulate leukocyte adhesion to endothelial cells through the nuclear receptor Nur77." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107844.

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Vascular endothelial growth factor (VEGF) and angiopoietin 1 (Ang-1) are critical regulators of angiogenesis. Additionally, both have been found to participate in inflammatory processes: VEGF as a pro-inflammatory and Ang-1 as an anti-inflammatory mediator. Nur77 is a member of a family of orphan receptors (NR4A) that includes Nurr1 and Nor1 and plays a role in regulating vascular inflammation; however, this has yet to be fully understood. The aim of this study was to evaluate whether Nur77 expression in endothelial cells (ECs) serves as a negative feedback mechanism designed to inhibit NFkapp
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Mangiante, Lee Elena Taylor Joan M. "The role of focal adhesion kinase in vascular smooth muscle cell migration." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,2137.

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Thesis (M.S.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Feb. 17, 2009). "... in partial fulfillment of the requirements for the degree of Master of Science in the Department of Pathology and Laboratory Medicine." Discipline: Pathology and Laboratory Medicine; Department/School: Medicine.
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Guyot, Viviane. "Expression tissulaire de la " neural cell adhesion molecule " et pronostic des cancers bronchiques opérés." Montpellier 1, 1992. http://www.theses.fr/1992MON11078.

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