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Journal articles on the topic 'Vcaop'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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1

Tsukasaki, Kunihiro, Atae Utsunomiya, Haruhiko Fukuda, et al. "VCAP-AMP-VECP Compared With Biweekly CHOP for Adult T-Cell Leukemia-Lymphoma: Japan Clinical Oncology Group Study JCOG9801." Journal of Clinical Oncology 25, no. 34 (2007): 5458–64. http://dx.doi.org/10.1200/jco.2007.11.9958.

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Purpose Our previous phase II trial for treating human T-lymphotropic virus type I–associated adult T-cell leukemia-lymphoma (ATLL) with vincristine, cyclophosphamide, doxorubicin, and prednisone (VCAP), doxorubicin, ranimustine, and prednisone (AMP), and vindesine, etoposide, carboplatin, and prednisone (VECP) showed promising results. To test the superiority of VCAP-AMP-VECP over biweekly cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), we conducted a randomized controlled trial exclusively for ATLL. Patients and Methods Previously untreated patients with aggressive ATLL we

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Isozaki, Eiji, Toshio Shimizu, Kiyomi Takamoto, et al. "Vocal cord abductor paralysis (VCAP) in Parkinson's disease: difference from VCAP in multiple system atrophy." Journal of the Neurological Sciences 130, no. 2 (1995): 197–202. http://dx.doi.org/10.1016/0022-510x(95)00030-6.

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Wang, Lyu, and Xiangling Wang. "Building virtual communities of practice in post-editing training: A mixed-method quasi-experimental study." Journal of Specialised Translation, no. 36 (July 25, 2021): 193–219. https://doi.org/10.26034/cm.jostrans.2021.041.

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Since post-editing of machine translation has become a widespread practice in the language service industry, post-editing training has been increasingly included in translation courses. The purpose of the study is to investigate the feasibility of implementing a virtual community of practice (VCoP) in training future post-editors that meet the market's needs. A VCoP refers to a social group sharing a common interest in an argument or a problem, interacting with each other by networks (Davis and Goodman 2014). Based on this concept, a VCoP method is postulated to facilitate online post-editing

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Ceccato, Pietro, Christelle Vancutsem, Robert Klaver, James Rowland, and Stephen J. Connor. "A Vectorial Capacity Product to Monitor Changing Malaria Transmission Potential in Epidemic Regions of Africa." Journal of Tropical Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/595948.

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Rainfall and temperature are two of the major factors triggering malaria epidemics in warm semi-arid (desert-fringe) and high altitude (highland-fringe) epidemic risk areas. The ability of the mosquitoes to transmitPlasmodiumspp. is dependent upon a series of biological features generally referred to as vectorial capacity. In this study, the vectorial capacity model (VCAP) was expanded to include the influence of rainfall and temperature variables on malaria transmission potential. Data from two remote sensing products were used to monitor rainfall and temperature and were integrated into the

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Boonlue, Surapon, Maneerat Manyuen, Jariya Neanchaleay, Atipat Boonmoh, and Vitsanu Nittayathammakul. "The Inquiry-Driven VCoP Model to Promote Digital Agriculturalists’ Learning Competencies in the Agriculture 4.0 Era." International Journal of Information and Education Technology 14, no. 1 (2024): 19–25. http://dx.doi.org/10.18178/ijiet.2024.14.1.2019.

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This research was conducted to develop the Inquiry-Driven Virtual Communities of Practice model (The ID VCoP model) in order to enhance the learning competencies of Thai digital agriculturists in preparation for the agriculture 4.0 era. The objectives of this study were to 1) develop the ID VCoP model to promote digital agriculturalists’ learning competencies, and 2) evaluate the suitability of the ID VCoP model. The research procedure consisted of two phases. The first phase involved the development of the model: 1) studying, analyzing, and synthesizing existing documents and previous researc

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Siltari, Aino, Merja Bläuer, Heimo Syvälä, Teuvo L. Tammela, and Teemu J. Murtola. "Abstract 121: Differential resistance to hypoxia is linked to increased lipid accumulation in treatment resistant prostate cancer cells." Cancer Research 82, no. 12_Supplement (2022): 121. http://dx.doi.org/10.1158/1538-7445.am2022-121.

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Abstract Introduction: Solid tumors typically favor non-oxygen related pathways on utilizing energy for cell metabolism. This helps tumor cells to survive in hypoxic microenvironment which is common in solid tumors such as prostate cancer (PCa). PCa cells characteristically store lipids, especially cholesterol. Furthermore, hypoxia and lipid metabolism are both associated with decreased responses to immune system and resistance to cancer treatments. Aim of this study was to investigate the impact of hypoxia on cell proliferation and lipid metabolism in advanced PCa cells at various stages of t

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Dunn, Sheila, Sarah Munro, Courtney Devane, et al. "A Virtual Community of Practice to Support Physician Uptake of a Novel Abortion Practice: Mixed Methods Case Study." Journal of Medical Internet Research 24, no. 5 (2022): e34302. http://dx.doi.org/10.2196/34302.

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Background Virtual communities of practice (VCoPs) have been used to support innovation and quality in clinical care. The drug mifepristone was introduced in Canada in 2017 for medical abortion. We created a VCoP to support implementation of mifepristone abortion practice across Canada. Objective The aim of this study was to describe the development and use of the Canadian Abortion Providers Support-Communauté de pratique canadienne sur l’avortement (CAPS-CPCA) VCoP and explore physicians’ experience with CAPS-CPCA and their views on its value in supporting implementation. Methods This was a m

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Hendrayani, Putri Fajar Ayu, Tamara Adriani Salim, Muhammad Prabu Wibowo, and Mad Khir Johari Abdullah Sani. "Benefit of Knowledge Sharing in Virtual Community of Practice (VCoP): A Systematic Literature Review." Palimpsest: Jurnal Ilmu Informasi dan Perpustakaan 16, no. 1 (2025): 34–53. https://doi.org/10.20473/pjil.v16i1.65880.

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Latar belakang: Knowledge sharing (KS) di Virtual Communities of Practice (VCoP) telah menjadi elemen kunci dalam menciptakan keunggulan kompetitif organisasi, terutama di era digital. Tujuan: Penelitian ini bertujuan untuk mengeksplorasi manfaat KS dalam VCoP melalui metode systematic literature review. Metode: Penelitian dilakukan dengan menganalisis 11 artikel primer yang dipilih menggunakan pendekatan PRISMA, mencakup publikasi dari 2019 hingga 2024, yang berfokus pada bagaimana KS meningkatkan pembelajaran individu, menciptakan pengetahuan baru, dan mendukung inovasi organisasi. Hasil: Ha

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Degano, Bruno, Marie Mittaine, Hervé Guénard, et al. "Nitric oxide and carbon monoxide lung transfer in patients with advanced liver cirrhosis." Journal of Applied Physiology 107, no. 1 (2009): 139–43. http://dx.doi.org/10.1152/japplphysiol.91621.2008.

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In advanced cirrhosis, decreased lung transfer for carbon monoxide (TLCO) and increased alveolar-arterial oxygen tension difference (PA-aO2 ≥15 mmHg while breathing ambient air) are frequently detected. Pulmonary membrane diffusion capacity for CO (DmCO) and pulmonary capillary blood volume (Vcap) can be derived from the simultaneous measurement of TLCO and lung transfer for nitric oxide (TLNO). Measurements of single-breath TLNO and TLCO were performed in 49 cirrhotic patients with advanced liver cirrhosis and in 35 healthy controls to derive Vcap, DmCO, and TLNO:TLCO ratio. Twenty-five patie

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Ferreira da Silva, Rogerio, Itana Maria de Souza Gimenes, and José Carlos Maldonado. "The Challenge of Evaluating Virtual Communities of Practice: A Systematic Mapping Study." Interdisciplinary Journal of Information, Knowledge, and Management 15 (2020): 039–64. http://dx.doi.org/10.28945/4505.

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Aim/Purpose: This paper presents a study of Virtual Communities of Practice (VCoP) evaluation methods that aims to identify their current status and impact on knowledge sharing. The purposes of the study are as follows: (i) to identify trends and research gaps in VCoP evaluation methods; and, (ii) to assist researchers to position new research activities in this domain. Background: VCoP have become a popular knowledge sharing mechanism for both individuals and organizations. Their evaluation process is complex; however, it is recognized as an essential means to provide evidences of community e

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Wannapiroon, Naphong. "International Virtual Communities of Practice (I-VCoP) with Immersive Learning Ecosystem for Enhancing Critical Communication Skills in Multicultural Society." International Journal of Information and Education Technology 15, no. 2 (2025): 335–47. https://doi.org/10.18178/ijiet.2025.15.2.2246.

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This research explores the integration of an Immersive Learning Ecosystem (ILE) within International Virtual Communities of Practice (I-VCoP) for enhancing critical communication skills in multicultural societies. The study aims to (1) conduct a PRISMA and bibliometric analysis of existing research related to Virtual Communities of Practice (VCoP), (2) develop I-VCoP with an immersive learning ecosystem, and (3) assess the critical communication skills of users engaged in I-VCoP activities. The immersive learning ecosystem leverages Virtual Reality (VR) and Augmented Reality (AR) technologies

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Fouzas, Sotirios, Anne-Christianne Kentgens, Olga Lagiou, et al. "Novel volumetric capnography indices measure ventilation inhomogeneity in cystic fibrosis." ERJ Open Research 8, no. 1 (2022): 00440–2021. http://dx.doi.org/10.1183/23120541.00440-2021.

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BackgroundVolumetric capnography (VCap) is a simpler alternative to multiple-breath washout (MBW) to detect ventilation inhomogeneity in patients with cystic fibrosis (CF). However, its diagnostic performance is influenced by breathing dynamics. We introduce two novel VCap indices, the capnographic inhomogeneity indices (CIIs), that may overcome this limitation and explore their diagnostic characteristics in a cohort of CF patients.MethodsWe analysed 320 N2-MBW trials from 50 CF patients and 65 controls (age 4–18 years) and calculated classical VCap indices, such as slope III (SIII) and the ca

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Eller, Kari. "Learning to (Co)Evolve: A Conceptual Review and Typology of Network Design in Global Health Virtual Communities of Practice." Interdisciplinary Journal of Information, Knowledge, and Management 19 (2024): 021. http://dx.doi.org/10.28945/5353.

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Aim/Purpose: This conceptual review analyzes the designs of global health virtual communities of practice (VCoPs) programming reported in the empirical literature and proposes a new typology of their functioning. The purpose of this review is to provide clarity on VCoP learning stages of (co)evolution and insight into VCoP (re)development efforts to best meet member, organization, and network needs against an ever-evolving landscape of complexity in global health. Background: Since the COVID-19 pandemic, the field of global health has seen an uptick in the use of VCoPs to support continuous le

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Dedzoe, Justice Dey-Seshie, Agneta Malmgren Fänge, Jonas Christensen, and Connie Lethin. "Collaborative Learning through a Virtual Community of Practice in Dementia Care Support: A Scoping Review." Healthcare 11, no. 5 (2023): 692. http://dx.doi.org/10.3390/healthcare11050692.

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The aim of this scoping review was to identify, synthesize, and report research on reflective collaborative learning through virtual communities of practice (vCoP), which, to our knowledge, is scarce. A second aim was to identify, synthesize, and report research on the facilitators and barriers associated with resilience capacity and knowledge acquisition through vCoP. The literature was searched in PsycINFO, CINAHL, Medline, EMBASE, Scopus, and Web of Science. The Preferred Reporting Items for Systematic Reviews (PRISMA) and Meta-Analyses for Scoping Reviews (ScR) framework guided the review.

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Moen, Pamela, and Kelley Walters. "Written Speech." International Journal of Online Pedagogy and Course Design 8, no. 4 (2018): 38–49. http://dx.doi.org/10.4018/ijopcd.2018100103.

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Data collected within this qualitative, multiple-case study included teachers' knowledge building preferences for written speech in a virtual community of practice (VCoP), blended learning, teacher professional development program. This data was analyzed using the theoretical tenets of Vygotsky's social constructivist learning theory. Through heterogeneous sampling, six sites were selected from 11 program participating schools, with 11 participating teachers purposively selected from these sites. Following semi-structured participant interviews, data were coded and analyzed, where the findings

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Ann Amaratunga, Carol. "Building community disaster resilience through a virtual community of practice (VCOP)." International Journal of Disaster Resilience in the Built Environment 5, no. 1 (2014): 66–78. http://dx.doi.org/10.1108/ijdrbe-05-2012-0012.

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Purpose – This paper aims to discuss a pilot in-progress project to promote community-based research (CBR) as a tool for disaster resilience planning in rural, remote and coastal communities. Using trans-disciplinary approaches, this project demonstrates how emergency and foresight planning in five rural Canadian pilot communities can be enhanced through the co-design of a pilot Web 2.0 “virtual community of practice” (VCOP). Design/methodology/approach – The VCOP initiative was designed with pilot and field site communities to facilitate knowledge generation and exchange and to enhance commun

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Ruslyakova, Irina A., Elvina Z. Shamsutdinova, Galina A. Mityuchenko, Alexandra O. Orlova, and Elena B. Avalueva. "Efficacy of Scoring Systems for Routing and Predicting Length of ICU Stay in Severe Community-Acquired Pneumonia." General Reanimatology 21, no. 1 (2025): 38–48. https://doi.org/10.15360/1813-9779-2025-1-38-48.

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Scoring systems based on assessment of disease severity and patient condition are widely used for routing and predicting length of stay in the ICU. However, their effectiveness varies in patients with sepsis.The aim of the study. To evaluate the effectiveness of scoring systems in routing and predicting ICU length of stay in patients with severe community-acquired pneumonia (CAP).Materials and methods. Medical records of 664 patients from the Intensive Care for Severe CAP database of I. I. Mechnikov Northwestern State Medical University (2013–2023) were analyzed using the following scoring sca

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Nätkin, Reetta, Pasi Pennanen, Heimo Syvälä, et al. "Abstract A012: Adaptive and non-adaptive gene expression responses in prostate cancer during androgen deprivation." Cancer Research 83, no. 11_Supplement (2023): A012. http://dx.doi.org/10.1158/1538-7445.prca2023-a012.

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Abstract Development of novel and efficient treatments for advanced prostate cancer (PCa) requires better understanding of the cellular mechanisms behind the transition to castration resistant prostate cancer (CRPC). We created long-term cell cultures to model the development of castration resistance. Using a low passage VCaP cells as an initial model, we first created a highly testosterone-dependent PCa cell line (VCaP-T) and then a subclone cell line developing the ability to grow at low testosterone concentration (VCaP-CT). Adaptation to low testosterone was solely due to long term culturin

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Lukic, Sandra, Connie Lethin, Jonas Christensen, and Agneta Malmgren Fänge. "Reflexive Views of Virtual Communities of Practice among Informal and Formal Caregivers of People with a Dementia Disease." Healthcare 12, no. 13 (2024): 1285. http://dx.doi.org/10.3390/healthcare12131285.

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Knowledge seems to mitigate the consequences of dementia and new educational strategies are required. This study aimed to qualitatively explore the reflexive views and experiences of virtual Communities of Practice (vCoP) among informal and formal caregivers of people with dementia and explore vCoP as a tool for learning and knowledge development. Data were collected in a sequence of virtual workshops and analyzed and synthesized using thematic analysis. For the informal caregivers, one main theme emerged: Learning and support, comprising three subthemes: Strategies for learning; Creating emot

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Barnett, Stephen, Sandra C. Jones, Sue Bennett, Don Iverson, and Andrew Bonney. "Usefulness of a virtual community of practice and Web 2.0 tools for general practice training: experiences and expectations of general practitioner registrars and supervisors." Australian Journal of Primary Health 19, no. 4 (2013): 292. http://dx.doi.org/10.1071/py13024.

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General practice training is a community of practice in which novices and experts share knowledge. However, there are barriers to knowledge sharing for general practioner (GP) registrars, including geographic and workplace isolation. Virtual communities of practice (VCoP) can be effective in overcoming these barriers using social media tools. The present study examined the perceived usefulness, features and barriers to implementing a VCoP for GP training. Following a survey study of GP registrars and supervisors on VCoP feasibility, a qualitative telephone interview study was undertaken within

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Bickle, Ed, Silvina Bishopp-Martin, Ursula Canton, et al. "Emerging from the third space chrysalis: Experiences in a non-hierarchical, collaborative research community of practice." Journal of University Teaching and Learning Practice 18, no. 7 (2021): 135–58. http://dx.doi.org/10.53761/1.18.7.9.

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This article discusses the creation of a research-focused virtual community of practice (vCoP) for geographically-dispersed third space professionals, motivated by desires for enhanced professional collaboration, visibility and identity. The authors used collaborative autoethnography (CAE) to evaluate their personal reflections as vCoP participants. Data were gathered in two collaborative writing activities and analysed using thematic analysis (TA). The TA identified two connected themes, which capture the vCoP members’ aspirations to transcend their current roles and be research-active throug

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Qutab, Saima, Abid Iqbal, Farasat Shafi Ullah, Nadeem Siddique, and Muhammad Ajmal Khan. "Role of virtual communities of practice (VCoP) in continuous professional development of librarians: a case of Yahoo mailing group from Pakistan." Library Management 43, no. 5 (2022): 317–33. http://dx.doi.org/10.1108/lm-02-2021-0017.

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PurposeVirtual communities of practice (VCoP) are becoming increasingly popular as professional networking. These communities support and shape professional development, especially in countries with limited opportunities and constrain like time and distance. This study throws light on the role of VCoP and its impact on the continuous professional development (CPD) of librarians in Pakistan.Design/methodology/approachThis study is carried out with qualitative research methods to understand effects of VCoP on CPD. With a thematic content analysis on the email conversations of a library and infor

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Zahra, Fatimah Az, and Shierly N. Yappi. "CLUBHOUSE AS VIRTUAL COMMUNITY OF PRACTICE FOR NON-NATIVE ENGLISH SPEAKERS TO PRACTICE." Academy of Education Journal 14, no. 2 (2023): 1351–62. http://dx.doi.org/10.47200/aoej.v14i2.2054.

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Clubhouse application, since it is found, becomes the popular application to practice English. It is because it is easy to use worldwide as well as provides good features and a community system. This case study investigated whether the Clubhouse application could become a virtual community of practice (VCoP) and motivate non-native English speakers (NNES) to speak within the community system. The data were collected through questionnaires with a Likert scale and semi-structured interviews. The participants were the members of the Smart and Easy English club, one of the biggest English clubs in

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Diniz, Odair Henrique Gaverio, Monica Corso Pereira, Silvia Maria Doria da Silva, Marcel Koenigkam-Santos, Ilma Aparecida Paschoal, and Marcos Mello Moreira. "Correlations between Volumetric Capnography and Automated Quantitative Computed Tomography Analysis in Patients with Severe COPD." Journal of Respiration 2, no. 1 (2022): 13–24. http://dx.doi.org/10.3390/jor2010002.

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Background: In chronic obstructive pulmonary disease (COPD), morphological analysis made by computed tomography (CT) is usually correlated with spirometry as the main functional tool. In this study, quantitative CT analysis (QCT) was compared with volumetric capnography (VCap), alongside spirometry and the 6-min walk test (6MWT). Methods: Twenty-seven patients with severe/very severe COPD were included, compared with nineteen control subjects. All participants performed spirometry and chest high resolution CT scans that were analyzed with fully-automated software. The COPD group was also submi

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Deshmukh, Ajita. "From Pixels to Personalities: Identity Formation in Virtual Communities through Multimodal Communication." European Conference on Social Media 11, no. 1 (2024): 50–58. http://dx.doi.org/10.34190/ecsm.11.1.2378.

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Communities of Practice (CoPs) are an important thread in the social fabric of knowledge sharing (Wenger, 2004). Members of CoPs who share a common passion and interact regularly in a bid to improve their discipline and expertise contribute thus to the cohort of knowledge and practice. Recently, due to the transformation of technology this interaction is no longer limited to the physical world but more than often it takes place using communication channels thus breaking the boundaries of time and space. This has led to the rise of the term Virtual Communities of Practice (VCoPs). It is recogni

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Rick, Ferenc G., Cale D. Fahrenholtz, Maria I. Garcia, Norman L. Block, Andrew V. Schally, and Kerry L. Burnstein. "Preclinical efficacy of growth hormone-releasing hormone antagonist MIA-602 for androgen-dependent and castration-resistant human prostate cancer." Journal of Clinical Oncology 32, no. 4_suppl (2014): 221. http://dx.doi.org/10.1200/jco.2014.32.4_suppl.221.

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221 Background: Advanced hormone-sensitive prostate cancer (PCa) responds to androgen deprivation therapy (ADT). However, therapeutic options for castration-resistant disease are limited. As growth hormone-releasing hormone receptor (GHRH-R) and ligand GHRH are regulated in an autocrine fashion in PCa, GHRH-R inhibition represents a novel approach to PCa treatment. We investigated the effects of a new, highly potent GHRH antagonist, MIA-602, on growth of androgen-dependent and castration-resistant PCa cells in vitro/in vivo. Methods: All three cell lines used in this study expressed androgen r

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Nakamura, Daisuke, Makoto Yoshimitsu, Tomohisa Tabuchi, et al. "OPEC/Mpec for Adult T-Cell Leukemia/Lymphoma: A Single-Institution Study." Blood 128, no. 22 (2016): 1828. http://dx.doi.org/10.1182/blood.v128.22.1828.1828.

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Abstract Introduction Adult T-cell leukemia/lymphoma(ATL) is a neoplasm of peripheral T-lymphocytes associated with human T-lymphotropic virus typeⅠ(HTLV-1), and its prognosis still remains very poor. VCAP-AMP-VECP, which is a sequential combination chemotherapy consisting of VCAP (vincristine, cyclophosphamide, doxorubicin, and prednisolone), AMP (doxorubicin, ranimustine, and prednisolone), and VECP (vindesine, etoposide, carboplatin, and prednisolone) has been considered to standard of care in Japan for the treatment of aggressive ATL (acute, lymphoma and chronic type with unfavorable progn

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Hafeez, Khalid, Fathalla M. Alghatas, Pantea Foroudi, Bang Nguyen, and Suraksha Gupta. "Knowledge sharing by entrepreneurs in a virtual community of practice (VCoP)." Information Technology & People 32, no. 2 (2019): 405–29. http://dx.doi.org/10.1108/itp-09-2016-0202.

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PurposeThe purpose of this paper is to examine how entrepreneurs engage in a virtual community of practice (VCoP) to share knowledge. Intensity of engagement is taken as a proxy to measure the strength of knowledge sharing.Design/methodology/approachThe archival data spanning over a three-year period from “Start-up-Nation©” (a VCoP purposefully setup for entrepreneurs) are used for analysis. A set of indices are introduced to measure participants’ intensity of engagement in terms of message length, message frequency and reciprocity in the knowledge sharing process. Content analysis is employed

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Mahesa Rani, Putu, Tamara Adriani Salim, and Muhammad Prabu Wibowo. "KNOWLEDGE MANAGEMENT IN VIRTUAL COMMUNITY OF PRACTICE (VCoP)." Jurnal Abdi Insani 11, no. 2 (2024): 1436–45. http://dx.doi.org/10.29303/abdiinsani.v11i2.1539.

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Manajemen Pengetahuan (KM) memainkan peran penting dalam organisasi untuk tetap kompetitif dan inovatif dalam lanskap global yang berkembang pesat saat ini. Komunitas Praktik Virtual (VCoPs) telah muncul sebagai platform berharga untuk berbagi pengetahuan dan kolaborasi antar individu dengan kepentingan profesional yang sama. Tujuan dari penelitian ini adalah untuk menganalisis bagaimana pengetahuan berkembang dalam praktik komunitas virtual berdasarkan konsep SECI oleh Nonaka Takeuchi. Data yang digunakan berasal dari karya tulis ilmiah tentang implementasi KM pada VCoPs di beberapa bidang pa

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Nätkin, Reetta, Pasi Pennanen, Heimo Syvälä, et al. "Adaptive and non-adaptive gene expression responses in prostate cancer during androgen deprivation." PLOS ONE 18, no. 2 (2023): e0281645. http://dx.doi.org/10.1371/journal.pone.0281645.

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Androgen deprivation therapy is the cornerstone treatment of advanced prostate cancer. Eventually prostate cancer cells overcome androgen deprivation therapy, giving rise to castration resistant prostate cancer (CRPC) characterized by increased androgen receptor (AR) activity. Understanding the cellular mechanisms leading to CRPC is needed for development of novel treatments. We used long-term cell cultures to model CRPC; a testosterone-dependent cell line (VCaP-T) and cell line adapted to grow in low testosterone (VCaP-CT). These were used to uncover persistent and adaptive responses to testo

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Kellam, Hugh, Clare Cook, Deborah L. Smith, and Pam Haight. "The Virtual Community of Practice Facilitation Model." International Journal of Technology and Human Interaction 19, no. 1 (2023): 1–14. http://dx.doi.org/10.4018/ijthi.328578.

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This study examines the instructional design, learning experiences, and outcomes of a virtual community of practice (VCoP). In 2019, the Northern Ontario School of Medicine launched a continuing professional development program consisting of an asynchronous online module followed by an optional series of facilitated case-based videoconference workshops, designed as a VCoP. This program evaluation study employed a convergent parallel mixed methods design and combined data sources from participant pre- and post-program surveys and reflections with a content analysis of semi-structured interviews

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Özgönül, Ali Mert, Aycan Aşık, Burak Durmaz, Ramin Aslaminabad, Cumhur Gündüz, and Eser Yıldırım Sozmen. "Antiproliferative effect of rosehip tea phenolics in prostate cancer cell lines." Turkish Journal of Biochemistry 45, no. 4 (2020): 423–28. http://dx.doi.org/10.1515/tjb-2019-0262.

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AbstractObjectivesRecently, phenolic compounds (quercetin, kaempferol, ellagic acid (EA), and myricetin) as natural sources have been suggested to be used for treatment and chemoprevention of prostate cancer. Since rosehip includes the above molecules in high concentration, we set out to investigate possible anti-proliferative effect of rosehip tea on the prostate cancer cell line.MethodsThe flavonol content of rosehip tea prepared at different temperatures and time intervals was determined first and then the antiproliferative effect of tea samples was established by adding tea samples to the

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Donnellan, Claudine, Niall Corcoran, and Matthew Cannon. "Investigating Knowledge Translation Dynamics for a Multi-Agency Response to Gender-Based Abuse." European Conference on Knowledge Management 25, no. 1 (2024): 190–98. http://dx.doi.org/10.34190/eckm.25.1.2429.

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Domestic, sexual, and gender-based abuse (DSGBA) is a complex societal issue with implications for individuals, families, and communities. According to the World Health Organisation, violence remains a pervasive problem, affecting one in three women globally. Addressing this complex issue requires the coordinated efforts of all agencies involved in the intervention and prevention of DSGBA. Despite shared goals, these agencies predominantly operate independently, resulting in the development of their own knowledge bases. Recognising the negative implications of agencies developing isolated know

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Campillejo, Alba, Ileana Gefaell-Larrondo, Vanesa Ramos-García, et al. "Implementation of a virtual community of practice to promote the empowerment of middle-aged people with multimorbidity: study protocol of a randomised controlled trial." BMJ Open 14, no. 5 (2024): e084937. http://dx.doi.org/10.1136/bmjopen-2024-084937.

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IntroductionEmpowering people living with multimorbidity (multiple chronic conditions) to gain greater confidence in managing their health can enhance their quality of life. Education focused on self-management is a key tool for fostering patient empowerment and is mostly provided on an individual basis. Virtual communities of practice (VCoP) present a unique opportunity for online education in chronic condition self-management within a social context. This research aims to evaluate the effectiveness/cost-effectiveness of individualised, online self-management education compared with VCoP amon

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Kaneko, Haruo, Ken Shikoshi, Shuichi Annou, et al. "VCAP Combination Chemotherapy for Multiple Myeloma in the Aged." Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 28, no. 4 (1991): 504–8. http://dx.doi.org/10.3143/geriatrics.28.504.

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Romero-Mas, Montse, Beni Gómez-Zúñiga, Andrew M. Cox, and Anna Ramon-Aribau. "Designing virtual communities of practice for informal caregivers of Alzheimer’s patients: An integrative review." Health Informatics Journal 26, no. 4 (2020): 2976–91. http://dx.doi.org/10.1177/1460458220950883.

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The main aim of this study is to review the literature to show how ideas around virtual communities of practice (VCoP) offer a model for supporting informal caregivers of Alzheimer’s patients (caregivers) to learn how to deal with caregiving demands. Caregivers are individuals who have a significant personal relationship with and provide a broad range of unpaid assistance to an older person or an adult with a chronic or disabling condition outside of a professional or formal framework. This review will examine the current evidence on the needs of caregivers, identify dimensions to be considere

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Romero-Mas, Montse, Anna Ramon-Aribau, Dyego Leandro Bezerra de Souza, Andrew M. Cox, and Beni Gómez-Zúñiga. "Improving the Quality of Life of Family Caregivers of People with Alzheimer’s Disease through Virtual Communities of Practice: A Quasiexperimental Study." International Journal of Alzheimer's Disease 2021 (April 5, 2021): 1–10. http://dx.doi.org/10.1155/2021/8817491.

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Caring for a person with dementia burdens family caregivers, and there is a close negative relationship between this burden and their quality of life (QoL). Research suggests that caregivers’ main needs are information and training about the disease and support from others experiencing the same situation, and Internet interventions hold considerable promise for meeting these needs. Virtual communities of practice (VCoPs) are Internet frameworks to share knowledge where members collaborate and achieve a sense of trust in the community. This paper seeks to evaluate the impact of participating in

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Pouliot, Frederic, Mélanie Rouleau, Bertrand Neveu, et al. "Contribution of extragonadal steroids to the androgen receptor activity and to the castration-resistance development in recurrent prostate cancers after primary therapy." Journal of Clinical Oncology 38, no. 6_suppl (2020): 148. http://dx.doi.org/10.1200/jco.2020.38.6_suppl.148.

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148 Background: Beyond testosterone, several steroids contribute to the activation of the androgen receptor (AR) pathway, but their relative contributions in castrated prostate cancer (PCa) patients remain unknown. Methods: Serum levels of nine steroids were measured by mass spectrometry from continuously castrated patients of the PR.7 study (n=219) and from the PCA24 cohort (n=116). For each steroid, standard curves for dose-dependent prostate-specific antigen promoter activation were built in castration-sensitive (LAPC4) and resistant (VCaP) PCa models. Standard curves were used to determine

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Izadmehr, Sudeh, Alexander Kirschenbaum, Shen Yao, and Alice C. Levine. "Prostatic Acid Phosphatase Is a Progenitor Cell Marker That Persists After Androgen Ablation." Journal of the Endocrine Society 5, Supplement_1 (2021): A1030—A1031. http://dx.doi.org/10.1210/jendso/bvab048.2108.

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Abstract Introduction: Prostatic Acid Phosphatase (PAP), a protein phosphatase and 5’ecto-nucleotidase, is expressed in prostate cancer (PCa) bone metastases and correlates with poor survival. Growing evidence suggests that PAP is not regulated by androgens, but rather by factors in the tumor microenvironment. Hypothesis: We hypothesized that PAP is a marker for a more progenitor type PCa cell and its expression is androgen-independent, persisting in castration-resistant disease. Methods: Protein expression of PAP and three androgen-regulated proteins, the Androgen Receptor (AR), Prostate-Spec

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Albert, Geeta, Goh See Kwong, and Nor Takrim Ibrahim. "Factors influencing professional virtual communities towards public service efficiency." European Conference on Knowledge Management 24, no. 1 (2023): 24–32. http://dx.doi.org/10.34190/eckm.24.1.1525.

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Communities of practice, which are often a central component of KM, are considered to be used to facilitate information sharing, resolve internal obstacles, and enhance mutual learning. The extensive use of ICT has enabled their transformation into a virtual environment – Professional Virtual Communities of Practice (VCoPs) – which is creating ideal conditions for collaborative information sharing and learning. This research examined factors predicting usage of the VCoP and how Malaysian public sector organisations, through their adoption, can influence their service efficiency. Based on the s

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Cheman, Shaik. "Safe, Clean and Unbiased Elections with Encrypted QR Code Voter Cards." International Journal on Cryptography and Information Security (IJCIS) 11, no. 1 (2021): 13. https://doi.org/10.5281/zenodo.5840171.

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The aim of this paper is to propose a novel approach to conducting safe, clean and unbiased elections by issuing Voter Cards with encrypted QR codes and including a new device called Voter Card Processor (VCAP) for verifying the issued voter cards at polling stations during elections. Detailed descriptions are provided of how to generate encrypted QR code voter cards, and how the VCAP functions in detecting fraudulent voter cards and repeat voters. This approach enables polling officers to automatically verify forgery of voter cards, identify and stop repeat voters, and also prevent rigging an

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Ramachandran, Balaji, Satheeshkumar Rajendiran, Rajendran Venkidusamy, Raghu Patil, Sachin Joshi, and Krishnappa Haladasappa. "Abstract 4759: Novel treatment approach for efficacy outcome in androgen dependent and independent prostate cancer orthotopic mice models." Cancer Research 85, no. 8_Supplement_1 (2025): 4759. https://doi.org/10.1158/1538-7445.am2025-4759.

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Abstract Prostate cancer is one of the leading cause of deaths worldwide. Orthotopic injection of cancer cells into mouse prostate remains significant challenge and orthotopic mouse models resemble human pathophysiology. In the current study Androgen dependent (LNCaP VCaP and VCaP-EnzR) and Androgen independent (PC3) cells were orthotopically inoculated (1x10^6 cells) into anterior prostate of male athymic nude mice. Seven to eleven days post implantation, the preclinical efficacy of Enzalutamide (15mg/kg, PO QD x 6 weeks) and Docetaxel (DTX; 7.5mg/kg, i.p Q7D x 6 weeks) as standalone and comb

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Katernyak, Ihor, Viktoriia Loboda, Ruslan Strotskyy, and Тetiana Мamatova. "VIRTUAL COMMUNITY OF PRACTICE FOR LOCAL DEVELOPMENT: DIVERSE CONTEXT AND PARTNERSHIP FOR ELEARNING IN PROJECT MANAGEMENT." Socio-economic relations in the digital society 4, no. 50 (2023): 172–83. http://dx.doi.org/10.55643/ser.4.50.2023.544.

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The purpose of this paper is to generate an in-depth and comprehensive understanding of knowledge management processes in the virtual Community of Practice (vCoP) and to propose a framework for organising an eLearning process in project management for local development. The vCoP was created on the web platform for exchanging best practices and learning within a group of professionals with specific experiences and diverse learning needs. For 10 years, the vCoP annually brought together from 600 to 1,000 participants from different regions and organisations who defined problems, learned from the

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Huang, Huarong, Yan He, Lanyue Zhang, et al. "Phenethyl isothiocyanate in combination with dibenzoylmethane inhibits the androgen-independent growth of prostate cancer cells." Food & Function 9, no. 4 (2018): 2398–408. http://dx.doi.org/10.1039/c7fo01983a.

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Hargrove, Amanda E., Thomas F. Martinez, Alissa A. Hare, et al. "Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide." PLOS ONE 10, no. 11 (2015): e0143161. http://dx.doi.org/10.1371/journal.pone.0143161.

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Loberg, Robert D., Lauren N. St. John, LaShon L. Day, Chris K. Neeley, and Kenneth J. Pienta. "Development of the VCaP androgen-independent model of prostate cancer." Urologic Oncology: Seminars and Original Investigations 24, no. 2 (2006): 161–68. http://dx.doi.org/10.1016/j.urolonc.2005.11.005.

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Hornung, Tassilo, Heather A. O’Neill, Stephen C. Logie, et al. "ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes." Nucleic Acids Research 48, no. 8 (2020): 4013–27. http://dx.doi.org/10.1093/nar/gkaa034.

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Abstract Libraries of single-stranded oligodeoxynucleotides (ssODNs) can be enriched for sequences that specifically bind molecules on naïve complex biological samples like cells or tissues. Depending on the enrichment strategy, the ssODNs can identify molecules specifically associated with a defined biological condition, for example a pathological phenotype, and thus are potentially useful for biomarker discovery. We performed ADAPT, a variant of SELEX, on exosomes secreted by VCaP prostate cancer cells. A library of ∼1011 ssODNs was enriched for those that bind to VCaP exosomes and discrimin

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Zwierzchowska, Anna, Eliza Gaweł, Agata Krużyńska, Kajetan J. Słomka, Aleksandra Żebrowska, and Grzegorz Juras. "Postural Stability of Adolescents with Late Cochlear Implantation and Hearing Aids: A Non-Randomized Trial." Audiology Research 14, no. 4 (2024): 572–80. http://dx.doi.org/10.3390/audiolres14040048.

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Background: The aim of this study was to assess the neuromuscular control of adolescents with late unilateral cochlear implantation and compare them to adolescents with hearing aids (HAs) while performing a balance task on a platform with the conditions of an activated hearing device (cochlear implant (CI)/HAs) with eyes opened/closed (EO/EC). Methods: Forty-eight adolescents with hearing loss participated in the study and were divided into SG (unilateral CI and HA) and CG (bilateral HA). The evaluation of the postural stability was performed with a force plate during two repeating testing tri

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Ghani, Manisa, Pauline Cooper-Ioelu, and Tanisha Jowsey. "Measuring the added value of virtual communities of practice for developing the educator role of critical care professionals." BMJ Open Quality 13, no. 1 (2024): e002556. http://dx.doi.org/10.1136/bmjoq-2023-002556.

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In healthcare settings, workplace learning is often supported by clinicians who strive to combine service provision and educator roles. We evaluated an international 12-month programme that supports widely distributed critical care health professional educators (HPEs) through a virtual community of practice (vCoP). Specifically, we evaluateifandhowthe vCoP approach affects learning experiences using an innovative evaluation framework in medical education—the value-creation framework (VCF). We used a mixed-methods approach to evaluation, including an anonymous survey and semistructured intervie

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Park, G. Yeon, and Jinhye Park. "Digital Discourse and Linguistic Proficiency: Sentiment Analysis of YouTube Comments in Informal English Learning Experiences." STEM Journal 26, no. 2 (2025): 58–78. https://doi.org/10.16875/stem.2025.26.2.58.

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This study investigates the potential of virtual communities of practice (VCoP) in English language education through sentiment analysis of YouTube comments on videos by Oliver Ssam (2022) and Moon Ga Young (2023). YouTube enables learners to exchange insights on English pronunciation and multilingual proficiency, fostering an interactive and collaborative learning environment through active engagement in comment sections. Sentiment analysis was conducted using the Sentiment VADER algorithm and Naïve Bayes classifier, achieving 94% and 96% accuracy rates for the respective videos. The study id

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