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1
Fiala, Václav. "Klasifikace typu vozidel (VCL)." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2016. http://www.nusl.cz/ntk/nusl-240922.
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This thesis deals with recognition of vehicles with image captured by one camera. The image is always taken as a front view of a vehicle passing one specific place in case of various lighting conditions. The aim is to implement classification method with regard to robustness, reliability and computional complexity. The method is implemented in Mircosoft Visual Studio 2013 using the OpenCV library.
2
He, Yanan. "Enhanced VCD in transition metal complexes and metalloproteins." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2005. http://wwwlib.umi.com/cr/syr/main.
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Turner, Helen Louise. "Absolute stereochemistry : the merits of VCD and XRD." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430715.
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Diamond-Stanic, Maggie Keck. "Diabetic Kidney Disease in the VCD Model of Menopause." Diss., The University of Arizona, 2008. http://hdl.handle.net/10150/195657.
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Kidney disease is a major complication of diabetes and accounts for one-third of all diabetes-related deaths. Estrogen is considered protective against cardiovascular and non-diabetic renal disease, however it is unclear if this protection extends to diabetes and diabetic kidney disease.To address these questions, we have used a new model of menopause in which repeated daily injections of 4-vinylcyclohexene (VCD) induces gradual ovarian failure in mice. Unlike with ovariectomy, the VCD model preserves the gradual transition into ovarian failure (OF) (modeling perimenopause). Also, following OF, the residual ovarian tissue is retained and secretes androgens, similar to the androgen production by postmenopausal human ovaries.The VCD model of menopause was combined with the streptozotocin (STZ) model of type 1 diabetes, and the development of diabetes and diabetic kidney damage were studied over the subsequent 6 weeks. We observed that blood glucose levels are higher in post-OF diabetic mice compared to cycling diabetic and peri-OF diabetic mice. Renal cell proliferation, an early marker of kidney damage, is increased in post-OF diabetic mice compared to cycling diabetic mice, as measured by expression of proliferating cell nuclear antigen. We also demonstrate that expression of α-smooth muscle actin is increased in post-OF diabetic mice compared to cycling diabetic mice. Five weeks after STZ injection, post-OF diabetic mice had higher rates of urine albumin excretion than cycling diabetic mice.Using real-time PCR, we identified changes in expression between post-OF diabetic and cycling diabetic mice of genes which have previously been associated with diabetic kidney damage. We also show that some of these changes occur in peri-OF diabetic mice as well. Using microarray, we identified 119 new genes which are regulated by the combination of ovarian failure and diabetes in the mouse kidney.These data support our hypothesis that the changes in hormones which occur during the transition into ovarian failure exacerbate the development and progression of diabetic kidney damage in mice. These data also highlight the utility and importance of the VCD model of menopause in the study of diabetic kidney damage.
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Haufe, Kati, Sylvie Meyer, Corina Jödicke, Jana Riedel, Eric Schoop, Bärbel Fürstenau, and Ralph Sonntag. "VCL-Transfer – Ein Projekt zum Erfahrungstransfer von virtuellen Gruppenlernprojekten." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-143286.
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Haufe, Kati, Sylvie Meyer, Corina Jödicke, Jana Riedel, Eric Schoop, Bärbel Fürstenau, and Ralph Sonntag. "VCL-Transfer – Ein Projekt zum Erfahrungstransfer von virtuellen Gruppenlernprojekten." Technische Universität Dresden, 2010. https://tud.qucosa.de/id/qucosa%3A27005.
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Meyer, David, Achim Zeileis, and Kurt Hornik. "The Strucplot Framework: Visualizing Multi-way Contingency Tables with vcd." Department of Statistics and Mathematics, WU Vienna University of Economics and Business, 2005. http://epub.wu.ac.at/480/1/document.pdf.
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This paper describes the `strucplot' framework for the visualization of multi-way contingency tables. Strucplot displays include hierarchical conditional plots such as mosaic, association, and sieve plots, and can be combined into more complex, specialized plots for visualizing conditional independence, GLMs, and the results of independence tests. The framework's modular design allows flexible customization of the plots' graphical appearance, including shading, labeling, spacing, and legend, by means of graphical appearance control (`grapcon') functions. The framework is provided by the R package vcd. (author's abstract)Series: Research Report Series / Department of Statistics and Mathematics
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Eder, Franziska. "VCL enhanced: Die sozialwissenschaftliche Dimension des Gruppenlernens im Virtual Classroom." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-141305.
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Im Rahmen des Bologna-Prozesses wird verstärkt auf Gruppenlernen und Virtualisierung gesetzt. Ziel dieses Beitrags ist eine Aussage über die Effektivität von Gruppenlernen im Virtual Classroom (VC) aus sozialwissenschaftlich-theoretischer Perspektive zu treffen.
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Eder, Franziska. "VCL enhanced: Die sozialwissenschaftliche Dimension des Gruppenlernens im Virtual Classroom." Technische Universität Dresden, 2008. https://tud.qucosa.de/id/qucosa%3A27947.
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Im Rahmen des Bologna-Prozesses wird verstärkt auf Gruppenlernen und Virtualisierung gesetzt. Ziel dieses Beitrags ist eine Aussage über die Effektivität von Gruppenlernen im Virtual Classroom (VC) aus sozialwissenschaftlich-theoretischer Perspektive zu treffen.
10
Hornik, Kurt, Achim Zeileis, and David Meyer. "The Strucplot Framework: Visualizing Multi-way Contingency Tables with vcd." American Statistical Association, 2006. http://epub.wu.ac.at/3984/1/strucplot.pdf.
Full textAbstract:
This paper describes the "strucplot" framework for the visualization of multi-way contingency
tables. Strucplot displays include hierarchical conditional plots such as mosaic,
association, and sieve plots, and can be combined into more complex, specialized plots for
visualizing conditional independence, GLMs, and the results of independence tests. The
framework's modular design allows flexible customization of the plots' graphical appearance,
including shading, labeling, spacing, and legend, by means of "graphical appearance
control" functions. The framework is provided by the R package vcd.
11
Craig, Zelieann Rivera. "Characterization of Residual Ovarian Tissue in Mice following 4-vinylcyclohexene Diepoxide-induced Ovarian Failure." Diss., The University of Arizona, 2009. http://hdl.handle.net/10150/195567.
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Menopause is associated with disorders such as osteoporosis and ovarian cancer. It is unclear whether the postmenopausal ovary retains steroidogenic capacity and how it can impact the development of these disorders. The present studies used the VCD-treated follicle-depleted mouse model of menopause to test the hypothesis that residual ovarian tissue retains steroidogenic capacity following ovarian failure and, thus, affects the development of these disorders. Microarray technology was used to evaluate gene expression in residual ovarian tissue of follicle-depleted mice compared to that in ovaries from cycling animals. Among the genes identified were those encoding proteins for synthesis of androgens. Steroidogenic capacity of residual ovarian tissue was further evaluated by determining the expression of genes and proteins involved in ovarian steroidogenesis, and by measuring levels of circulating and rostenedione and gonadotropins. Follicle-depleted ovaries were enriched in mRNAs for androgenic enzymes, receptors involved in the internalization of cholesterol, and luteinizing hormone receptor. Increased circulating levels of FSH and LH and detectable and rostenedione were measured throughout the study. Protein for 3β-hydroxysteroid dehydrogenase, 17α- hydroxylase/17,20-lyase and luteinizing hormone receptor was detected in follicledepleted ovaries by Western blot analysis and localized by immunofluorescence staining. The contribution of retaining residual ovarian tissue to accelerated bone loss following ovarian failure was evaluated by comparing bone mineral density from young and aged VCD-treated mice to that in age-matched ovariectomized (OVX) animals. Retaining residual ovarian tissue resulted in protection against accelerated bone loss in young but not aged VCD-treated mice. Whether residual ovarian tissue is more susceptible to development of ovarian neoplasms compared to ovaries from cycling animals was addressed by combining the VCD-treated mouse with the DMBA model of ovarian carcinogenesis. VCD-treated follicle-depleted mice that received DMBA developed Sertoli-Leydig cell tumors while no tumors were observed in cycling animals. Residual ovarian tissue following ovarian failure appears to have a protective effect against loss of bone integrity, but a detrimental effect on development of ovarian neoplasms. Findings from these studies: provided evidence of a physiological role for residual ovarian tissue following ovarian failure, and furthered the use of the VCD-treated mouse as a relevant model for menopause and associated disorders.
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Rajapaksa, Kathila Seuwandhi. "The Role of Ovarian Metabolism in 4-Vinylcyclohexene Metabolites and 7,12-Dimethylbenz[a]anthracene Induced Ovotoxicity in Mice." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/194403.
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Ovarian toxicants 4-vinylcychlohexene (VCH) and 7,12-dimethylbenz[a]anthracene (DMBA) requires bioactivation to induce follicle loss. VCH is bioactivated to monoepoxides (1,2-VCM and 7,8-VCM), and subsequently to an ovotoxic diepoxide (VCD) by hepatic CYP 2A and CYP 2B. DMBA is sequentially bioactivated to the ovotoxicant DMBA-3,4-diol-1,2-epoxide by hepatic CYP 1B1, microsomal epoxide hydrolase (mEH), and CYP 1A1/1B1 enzymes. Even though the liver is the primary organ metabolizing VCH and DMBA to reactive intermediates, several studies suggest that the ovary can also metabolize these two compounds. Studies were designed to investigate the role of ovarian metabolism in the resulting ovotoxicity of these two compounds using a novel mouse ovarian culture system. The hypothesis was that the ovary can participate in bioactivation and detoxification of VCH/VCM and DMBA and thereby influence the resulting ovotoxicity.Postnatal day 4 CYP 2E1 wild-type, null and B6C3F1 mouse ovaries were incubated with 1,2-VCM, VCD or DMBA for various lengths of time. 28 day old female CYP 2E1 wild-type and null mice were dosed (15d, i.p) with VCH, 1,2-VCM, VCD, or sesame oil (control). Following incubations and dosing, ovaries were prepared for histological evaluation of follicle numbers, mEH mRNA level, or mEH protein level. Medium from cultures were analyzed by LC/MS for VCD-GSH adducts.DMBA was found to be a potent ovotoxicant compared to VCH/VCM/VCD. In the ovarian culture system, VCM-induced toxicity required the CYP 2E1 enzyme. However, in vivo dosing studies indicated that in the presence of hepatic metabolism the ovary plays a minimal role in VCH/VCM-induced toxicity. Studies utilizing LC/MS showed that once bioactivated to VCD, this ovotoxic metabolite can be detoxified by glutathione conjugation in the ovary. Follicle loss induced by the ovotoxicant DMBA was found to involve mEH enzyme in culture.Collectively, these studies show that the ovary has the capacity to bioactivate and detoxify ovotoxicants. In the presence of hepatic metabolism ovarian effects might play only a minimal role in the resulting toxicity. The role of ovarian metabolism in the whole animal needs to be further investigated, especially for potent toxicants such as DMBA that can induce ovotoxicity at nanomolar concentrations.
13
Balazs, Ildiko Erzsebet. "Konzeption von Virtual Collaborative Learning Projekten." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1111134624957-21292.
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Virtual Collaborative Learning (VCL) beschäftigt sich mit einer Möglichkeit, Lernenden eine virtuelle Lernumgebung zu bieten, in der sie die Vorteile von E-Learning, wie zeitliche Flexibilität oder Ortsunabhängigkeit, mit den Vorteilen einer kollaborativen Zusammenarbeit kombinieren können. Hierbei steht die systematisch vorbereitete, tutoriell begleitete, unter Projektbedingungen (klare Zielvorgabe, offener Lösungsweg, begrenzte personelle und zeitliche Ressourcen) realisierte und mit Hilfe von Informations- und Kommunikationstechnologie hauptsächlich in virtueller Umgebung stattfindende, selbstorganisierte Kleingruppenarbeit an authentischen Problemstellungen im Mittelpunkt. Das Ziel der vorliegenden Arbeit ist die Unterstützung eines Entscheidungsträgers beim Treffen von VCL-bezogenen Planungsentscheidungen und somit die Erhöhung der Wahrscheinlichkeit eines erfolgreichen Einsatzes dieser Lehrform. Hierfür wurden basierend auf den Erfahrungen und Daten, die innerhalb von sieben VCL Projekten zwischen 2001 und 2003 am Lehrstuhl für Wirtschaftsinformatik, insb. Informationsmanagement, der Technischen Universität Dresden gesammelt und ausgewertet wurden, die Besonderheiten eines VCL Einsatzes systematisiert und ein Vorgehensmodell zur Unterstützung des Entscheidungsträgers abstrahiert. Die im Teil A der Arbeit vorgestellten Informationen ermöglichen dem Leser, Virtual Collaborative Learning in die Vielzahl unterschiedlicher Lehrformen der virtuellen Gruppenarbeit einzuordnen, eine präzise Vorstellung über die mit VCL erreichbaren Ziele zu gewinnen und VCL im Detail kennen zu lernen. Dieses Wissen ist notwendig, um das im Teil B vorgestellte Vorgehensmodell erfolgversprechend nutzen zu können. Das Vorgehensmodell teilt den gesamten Entscheidungsprozess in einzelne Phasen, die Phasen in mehrere Schritte und die Ermittlung möglicher Alternativen in mehrere aufeinander aufbauende Module auf. Zu den einzelnen Vorgehensschritten stehen dem Entscheidungsträger im Anhang unterstützende Informationen, abgeleiteten Empfehlungen, Checklisten und abstrahierte Regeln zur Verfügung.
14
Wertheim, Adolf. "Využití diagnostické sady VAG-COM PROFI v soudním inženýrství." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-232856.
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The thesis deals with possibilities of application of VAG-COM PROFI diagnostic kit in forensic engineering. After defining a theoretical basis, according to possibilities of evaluation of technical condition of a vehicle, the thesis is focused on applying diagnostic methods using above mentioned diagnostic kit. With respect to opportunities of identification of driving parameters, possibility of acceleration measurement and estimation of engine power are introduced. Describing of methodology and making the final statement are contained in the thesis as a part of every single measurement.
15
Oliveira, Nayara Pestana de. "Efeitos da terapia estrogênica sobre a neuroquímica de fêmeas em modelo animal de perimenopausa (rata) induzida pelo 4-diepóxido de vinilciclohexano." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17134/tde-23072018-104343/.
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A perimenopausa representa a transição da vida reprodutiva para não reprodutiva. É geralmente caracterizada por alterações neuroendócrinas, metabólicas e comportamentais, um possível resultado da depleção folicular ovariana e consequente redução do número de folículos ovarianos. É o período em que as mulheres podem apresentar maior susceptibilidade a manifestar transtornos afetivos e de ansiedade. A exposição de roedores ao resíduo químico 4-diepóxido de vinilciclohexeno (VCD) é um modelo bem estabelecido para estudos sobre perimenopausa, pois o VCD acelera o processo natural de atresia folicular. Embora as concentrações plasmáticas de estradiol estejam normais ou elevadas durante a perimenopausa, a terapia com estradiol pode ser benéfica para mulheres sintomáticas na perimenopausa. Portanto, o objetivo do presente trabalho foi investigar se a depleção folicular gradativa acelerada pelo VCD resulta em alterações na neuroquímica de ratas fêmeas em núcleos cerebrais que controlam o humor, além de avaliar se o estradiol seria capaz de reverter as possíveis alterações. Ratas da linhagem Wistar (28 dias pós-natal) receberam diariamente, durante 15 dias consecutivos, injeções subcutâneas de VCD (160 mg / kg) ou óleo de milho (O). Aproximadamente 55 dias após a primeira injeção, cápsulas de silastic contendo 17?-estradiol (E) ou O foram inseridas subcutaneamente (Grupos O+O; VCD+O; VCD+E). Cerca de 21 dias após o implante das cápsulas, as ratas dos grupos O+O e VCD+O foram decapitadas na manhã do diestro, enquanto que as do grupo VCD+E foram decapitadas exatamente 21 dias após o implante das cápsulas contendo estradiol, entre 0900 h e 1100 h. O sangue foi colhido para avaliação das concentrações plasmáticas de estradiol e progesterona por radioimunoensaio (RIE). Os cérebros foram removidos para microdissecção do hipocampo, amígdala, Locus coeruleus (LC) e Núcleo Dorsal da Rafe (NDR), para posterior análise dos níveis de RNAm para os receptores de progesterona (PR) e estradiol do tipo beta (ER?) por meio de RT/PCR. Este experimento foi replicado para remoção do hipocampo e amígdala para dosagem dos conteúdos de noradrenalina (NA) e serotonina (5-HT) por meio de cromatografia líquida de alta performance, seguida de detecção eletroquímica (HPLC/ED). Outro conjunto de ratas submetidas às mesmas condições10 experimentais foi perfundido para imunohistoquímica para TPH no NDR e TH no LC. Como esperado, na periestropausa (grupo VCD+O) as concentrações plasmáticas de estradiol não foram diferentes daquelas das ratas controles (O+O). As concentrações plasmáticas de progesterona na periestropausa foram menores que as do grupo controle, o que foi revertido pelo estradiol. No LC, a expressão de PR na periestropausa foi igual à das ratas controles, enquanto a expressão do ER? foi menor; a terapia com estradiol não modificou a expressão de nenhum destes receptores. A densidade de neurônios noradrenérgicos (TH+) no LC não foi alterada nem pela depleção folicular nem pela terapia estrogênica. Na periestropausa, o conteúdo de NA foi menor na amígdala, mas não no hipocampo, e o estradiol não alterou este conteúdo em nenhuma das áreas. No NDR, a expressão de PR e de ER? nas ratas na periestropausa foi menor que nas ratas controles; o estradiol preveniu o declínio da expressão de ER?, mas não de PR. O NDR foi analisado separadamente por toda a extensão rostro-caudal em 3 níveis anatômicos: rostral, médio e caudal, cada um dividido em 3 sub-regiões: lateral, dorsal e ventral. O número de neurônios serotonérgicos (TPH+) no NDR foi menor na periestropausa, e o estradiol foi capaz de reverter esse efeito, atuando principalmente na região caudal. A expressão gênica de PR não foi alterada nem pela depleção folicular nem pela terapia estrogênica tanto na amígdala como no hipocampo. A expressão de ER? também não foi diferente na periestropausa, quando comparada ao grupo controle, mas o estradiol aumentou esta expressão no hipocampo. Tanto na amígdala como no hipocampo houve redução no conteúdo de 5-HT na periestropausa e estradiol foi capaz de reestabelecer os níveis deste neurotransmissor aos valores controles apenas no hipocampo. Estes dados elucidam, pelo menos em parte os mecanismos do efeito positivo da terapia estrogênica nos sintomas de mulheres normoestrogênicas na perimenopausa. Estes efeitos parecem não envolver de forma importante o sistema noradrenérgico central, mas resultar do aumento da biossíntese de progesterona periférica em associação com a regulação positiva de ER? no NDR e hipocampo, que parece potencializar a via serotonérgica NDR/HPC. Portanto, o desenvolvimento de novas terapias que ativem os ER? pode ser uma alternativa para obter os efeitos positivos da ação do estradiol, eliminando os efeitos colaterais das terapias de estradiol que normalmente resultam da ativação do ER?.Perimenopause represents the transition from reproductive to non-reproductive life. It is usually characterized by neuroendocrine, metabolic and behavioural changes, which result from a follicular depletion and reduced number of ovarian follicles. During this period, women are more likely to express mood disorders and anxiety. The exposure of animals to diepoxide 4-vinylcyclohexene (VCD) is a well-established experimental model for perimenopause studies, as VCD induces loss of ovarian small follicles (primary and primordial) in mice and rats by accelerating the natural process of atresia. Although estrogens levels are normal or even high during perimenopause, estrogen therapy can be beneficial for symptomatic perimenopausal women. The aim of this study was to investigate whether gradual follicular depletion induced by VCD results in changes in the neurochemistry of female rats in brain nuclei that control mood and the role of estradiol on these changes. Female rats (28 days) were daily injected with VCD or corn oil (O) for 15 days. Around 55 days after the first injection, pellets of 17?-estradiol (E) or O were inserted s.c (Groups O+O; VCD+O; VCD+E). Around 21 days after, rats O+O and VCD+O were decapitated between 0900 h and 1100 of diestrus while rats VCD+E were decapitated exactly 21 days after the onset of E therapy. Another set of rats followed the same experimental design and were perfused for TH and TPH immunohistochemistry in Locus coeruleus (LC) and Dorsal Raphe Nuclei (DRN), respectively. Blood was collected for estradiol and progesterone measurement by radioimmunoassay (RIA). The brains were removed from decapitated rats to punch out LC, DRN, hippocampus and amygdala to analyse the expression of mRNA for ER? and PR by RT/PCR. This experiment was replicated to punch out the hippocampus and amygdala for the determination of noradrenaline (NE) and serotonin (5-HT) contents by High Performance Liquid Chromatography, followed by Electrochemical Detection (HPLC/ED). As expected, plasma concentrations of estradiol were not different from those of control rats (O + O). Plasma concentrations of progesterone in the periestropause were lower than those in the control group, which was reversed by estradiol. In the LC, the PR expression in the periestropause was similar to that of the control rats, whereas the ER? expression was lower; estradiol therapy did not modify the expression of any of these receptors. The12 density of noradrenergic (TH +) neurons in LC was not altered by either follicular depletion or estrogen therapy. In periestropause, NA content was lower in the amygdala, but not in the hippocampus, and estradiol did not alter this content in any of the areas. In NDR, the expression of PR and ER? in periestropausal rats was lower than in controls; estradiol prevented the decrease of ER? expression, but not PR. The NDR was analyzed separately for the entire rostrocaudal axis in three anatomical levels: rostral, middle and caudal, each divided into three sub-regions: lateral, dorsal and ventral. The number of serotonergic neurons (TPH +) in NDR was lower in the periestropause, and estradiol was able to reverse this effect, acting mainly in the caudal region. PR gene expression was not altered by either follicular depletion or estrogen therapy in either the amygdala or the hippocampus. ER? expression was also no different in periestropause compared to the control group, but estradiol increased this expression in the hippocampus. Both in the amygdala and in the hippocampus there was a reduction in 5-HT content in the periestropause, and estradiol was able to reestablish the levels of this neurotransmitter at the control values only in the hippocampus. These data elucidate, at least in part, the mechanisms of the positive effect of estrogen therapy on the symptoms of normoestrogenic women in perimenopause. These effects do not appear to significantly involve the central noradrenergic system but result from increased peripheral progesterone biosynthesis in association with positive regulation of ER? in the NDR and hippocampus, which appears to potentiate the serotonergic NDR/HPC pathway. Therefore, the development of new therapies that activate ER? may be an alternative to obtain the positive effects of the estradiol action, eliminating the side effects of the estradiol therapies that normally result from the activation of ER?.
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Balazs, Ildiko Erzsebet. "Konzeption von Virtual Collaborative Learning Projekten: Ein Vorgehen zur systematischen Entscheidungsfindung." Doctoral thesis, Technische Universität Dresden, 2004. https://tud.qucosa.de/id/qucosa%3A24468.
Full textAbstract:
Virtual Collaborative Learning (VCL) beschäftigt sich mit einer Möglichkeit, Lernenden eine virtuelle Lernumgebung zu bieten, in der sie die Vorteile von E-Learning, wie zeitliche Flexibilität oder Ortsunabhängigkeit, mit den Vorteilen einer kollaborativen Zusammenarbeit kombinieren können. Hierbei steht die systematisch vorbereitete, tutoriell begleitete, unter Projektbedingungen (klare Zielvorgabe, offener Lösungsweg, begrenzte personelle und zeitliche Ressourcen) realisierte und mit Hilfe von Informations- und Kommunikationstechnologie hauptsächlich in virtueller Umgebung stattfindende, selbstorganisierte Kleingruppenarbeit an authentischen Problemstellungen im Mittelpunkt. Das Ziel der vorliegenden Arbeit ist die Unterstützung eines Entscheidungsträgers beim Treffen von VCL-bezogenen Planungsentscheidungen und somit die Erhöhung der Wahrscheinlichkeit eines erfolgreichen Einsatzes dieser Lehrform. Hierfür wurden basierend auf den Erfahrungen und Daten, die innerhalb von sieben VCL Projekten zwischen 2001 und 2003 am Lehrstuhl für Wirtschaftsinformatik, insb. Informationsmanagement, der Technischen Universität Dresden gesammelt und ausgewertet wurden, die Besonderheiten eines VCL Einsatzes systematisiert und ein Vorgehensmodell zur Unterstützung des Entscheidungsträgers abstrahiert. Die im Teil A der Arbeit vorgestellten Informationen ermöglichen dem Leser, Virtual Collaborative Learning in die Vielzahl unterschiedlicher Lehrformen der virtuellen Gruppenarbeit einzuordnen, eine präzise Vorstellung über die mit VCL erreichbaren Ziele zu gewinnen und VCL im Detail kennen zu lernen. Dieses Wissen ist notwendig, um das im Teil B vorgestellte Vorgehensmodell erfolgversprechend nutzen zu können. Das Vorgehensmodell teilt den gesamten Entscheidungsprozess in einzelne Phasen, die Phasen in mehrere Schritte und die Ermittlung möglicher Alternativen in mehrere aufeinander aufbauende Module auf. Zu den einzelnen Vorgehensschritten stehen dem Entscheidungsträger im Anhang unterstützende Informationen, abgeleiteten Empfehlungen, Checklisten und abstrahierte Regeln zur Verfügung.
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Yala, Louiza. "Content Delivery Networks as a Service (CDNaaS)." Thesis, Rennes 1, 2018. http://www.theses.fr/2018REN1S097/document.
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Le but de cette thèse est d’étudier et d’évaluer le rôle de la virtualisation des réseau de diffusion de contenu. Nous proposons une implémentation d’une architecture CDN permettant à un opérateur de réseau de virtualiser son infrastructure CDN et de la louer à des fournisseurs de contenu. Afin d’avoir une allocation optimale des ressources, nous proposons une méthode qui combine les informations fournies lors de la demande par le fournisseur de contenu avec les données du réseau et de l’infrastructure de calcul. Nous avons modélisé ce problème d’allocation de ressources en problème d’optimisation, résolu par un algorithme. Les résultats obtenues donnent suite à la proposition d’algorithmes et d’heuristiques de placement pour l’allocation conjointe de vCPU-à-VM et le placement des VMs dans les PmsThe goal of this thesis is to study and evaluate the role a Virtual CDNs in improving the end-users QoE while saving on service providers’ costs and service availability. First, we present the design and implementation of an architecture for on-demand deployment of a vCDN infrastructure over a telco cloud. Second, we propose different algorithms for solving the Virtual Network Function (VNF) placement problem. We propose a polynomialtime heuristic algorithms to solve a relaxed version of the problem’s assumptions, we show experimentally that the derived solutions are close to the optimal. Finally, we study and evaluate solutions for the placement of VNF at the edge, by moving from the traditional central cloud to the edge one. We have also shown how our method can reduce delays and still provide a highly-available service
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Kaskar, Khalied. "Evaluation of quantitative motility and zona pellucida binding of human spermatozoa in an assisted reproductive programme." University of the Western Cape, 1994. http://hdl.handle.net/11394/8416.
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>Magister Scientiae - MScMale factor disorders affect more than 30% of infertile couples. Thus, it has become important to perform a andrological consultation and a basic semen evaluation in all male partners of couples consulting for infertility. The advent and development of assisted reproductive technologies has not only improved clinical results but also enhanced our basic understanding of the physiology of sperm and sperm preparation methods. Assisted reproduction has become among the more successful therapeutic modalities for a wide variety of sperm function disorders e.g. artificial insemination and in vitro fertilization (IVF) (Acosta et al. 1989). It is clear from recent experience that patients with male infertility showing oligozoospermia, asthenozoospermia, teratozoospermia (sometimes in combination), male immunological factor (antisperm antibodies) or ejaculatory problems as well as congenital abnormalities, can be successfully treated with IVF and embryo transfer. Prerequisite pre-fertilization changes by sperm, termed "capacitation" (Austin 1952) provides sperm with the capacity to fertilize eggs. These processes are generally regarded as encompassing all pre-fertilization changes occurring in sperm up 'to, but not including, loss of the acrosome (Bedford 1970). The endpoints of capacitation are often described as the acrosomal loss as well as changes in the motion characteristics. Capacitation alters the pattern of motility exhibited by freely swimming sperm, changing from a fairly rigid flagellar beat pattern to one of extreme flexure, often associated with increased thrust (Johnson et al. 1981) , which is referred to as hyperactivated motility (Yanagimachi 1981). without the transition to hyperactivated motility, sperm are unable to penetrate the zona pellucida (Fraser 1981), and possibly unable to fertilize eggs. Hyperactivation per se is marked by increased curvature in swimming trajectories and/or increased lateral displacement of the sperm head along their path (Burkman 1984). However, the physiological role of this change in motility is not clearly understood because almost all relevant data have been obtained under in vitro conditions. The association of specific seminal characteristics (sperm concentration, percentage motile cells and percentage normal sperm morphology) with the success rate of assisted particular has been The analysis of 1984; the reproductive techniques and IVF in under great scrutiny (Mahadevan and Trounson relationships between conventional semen parameters and fertilization rates in vitro has shown that sperm motility, concentration and morphology must be considered in estimating opportunities for successful intervention, as in the case of IVF and gamete intrafallopian transfer (GIFT) (Oehninger and Hodgen 1991). A reduction in the percentage of progressive motility alone does not seem to have a significant impact on IVF results unless it is below a threshold value of 10%. The semen sample should have an acceptable sperm concentration and morphology and/or that at least 1.5 X 106 motile spermatozoa can be recovered after swim-up separation (Acosta et al. 1989).
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Knipper, Richard [Verfasser], Jürgen [Gutachter] Popp, and Heidemarie [Gutachter] Schmidt. "Plasmonische Metamaterial-Strukturen als Quellen gesteigerter Sensitivität in FT-IR- und VCD-Messsystemen / Richard Knipper ; Gutachter: Jürgen Popp, Heidemarie Schmidt." Jena : Friedrich-Schiller-Universität Jena, 2018. http://d-nb.info/1205884947/34.
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Peters, Nils. "Enantioselektive HPLC-Trennung und VCD-Strukturbestimmung von atropisomeren MeSO2-PCB sowie Studien über deren Toxizität und deren Verteilung in Biota-Proben." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=966002849.
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Lipovka, Yulia. "Estrogen Dependent Regulation of the Amp-Activated Protein Kinase Pathway." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/556852.
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Sex differences exist in the progression of heart disease, as premenopausal women are protected from developing severe hypertension, aortic stenosis, myocardial infarction and hypertrophic cardiomyopathies. The susceptibility and progression of cardiovascular disease increases in post-menopausal women. This is at least partially underlined by a pronounced decrease in circulating estrogen levels. Estradiol (E2), the most abundant estrogen in premenopausal women, is known to be cardioprotective. Recently, AMP-activated protein kinase (AMPK) has emerged as a prominent player in the development of cardiac hypertrophy and heart failure. AMPK is central to the energetic metabolism of the cell and is activated in response to energy deprivation. E2 has been shown to activate AMPK, by yet an unknown mechanism. The first part of this dissertation focuses on describing the molecular mechanism behind this AMPK activation. We found that E2 activates AMPK through a non- genomic pathway and involves direct interaction of classical estrogen receptors (ERα and ERβ) with the α-catalytic subunit of AMPK. These receptors also associate with the upstream kinase LKB1, which is required for E2-dependent activation of AMPK. Furthermore, the two estrogen receptors play opposite roles, where ERα increases AMPK activation, and ERβ acts as a repressor, inhibiting AMPK phosphorylation. To translate our findings to heart disease, the next step was to determine the effect of ovarian failure, underlined by E2 loss, on AMPK signaling during the progression of cardiac hypertrophy. We hypothesized that ovarian failure decreases cardiac AMPK signaling, translating in worsening of hypertrophy. We found that the status of cardiac AMPK signaling depends on the nature of the hypertrophic stimulus and the timing of ovarian failure in relation to the onset of hypertrophy. Furthermore, we did not detect any differences in the development of cardiac hypertrophy between wild type mice and mice in ovarian failure, which most likely occur down the line. In summary we described a novel mechanism of AMPK activation by the hormone E2. We also explored the effect of estrogen loss on cardiac AMPK activity, and found that it is dependent on factors such as the pathological state of the heart and timing of the intervention. These findings add to our understanding of the molecular mechanisms behind sex differences in energy handling and in the future could be translated into better therapeutics for the treatment of cardiac pathologies.
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Rossi, Iuliana. "L'effet paravent des TICE." Thesis, Cergy-Pontoise, 2014. http://www.theses.fr/2014CERG0696/document.
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L'effet paravent est une proposition contradictoire à l'effet Pygmalion. Les études de Rosenthal et Jacobson ont mis en évidence le fait que les attentes des enseignants ont comme résultat la tendance de l'élève à se conformer à ces attentes. Par conséquent, les élèves considérés comme susceptibles de s'épanouir arrivent à obtenir des résultats supérieurs aux résultats des autres élèves (et inverse pour les élèves faibles). Mais, les enseignants élaborent souvent des attentes en prenant en compte des éléments qui ne se situent pas dans une relation directe avec les performances scolaires. Le genre, l'origine ethnique, la classe socioéconomique, l'attractivité physique sont des facteurs qui influencent l'élaboration des attentes par les enseignantes, malgré leurs caractères moins fiables. L'essor des technologies, ces dernières années, leur utilisation massive et à grande échelle au niveau de la société, ainsi que leur introduction dans les écoles semblent offrir de nouvelles perspectives, y compris celle de l'amélioration des résultats des élèves, dus aux représentations erronées des enseignants à l'égard de potentiel cognitif de leurs élèves. En effet, avec les technologies, l'école trouve de nouvelles ressources pour accomplir sa mission. Compte tenu de ces nouvelles conditions de travail et d'apprentissages apportées par l'utilisation des technologies, un certain nombre de questions surgissent en lien direct avec les possibilités de changer les regards des enseignants concernant les performances des élèves, avec des effets bénéfiques sur l'image de soi des élèves et, pourquoi pas, sur leurs résultats scolaires. Pour répondre à ces questions, ce travail propose l'étude de l'effet paravent des TICE, autrement dit, la possibilité d'utiliser les TICE pour contrecarrer les effets d'attentes des enseignants sur les performances des élèves. Dans cette perspective, des technologies permettant l'assurance de l'anonymat apparaissent comme un élément susceptible de briser la relation classique maître-élèveThe screening effect is opposite proposal to the so called Pygmalion effect. Early studies of Rosenthal and Jacobson had proven the pupils' tendency to reach teacher's expectations concerning theirs scholar performances. It follows that the students considered as promising get usually better results than the others (and contrary, those one considered as weak got lower results). Nevertheless the teacher expectations are sometime based on facts that are not direct linked to the scholar performances. Despite theirs reliability, the gender, the ethnical origin, the social level and physical attractiveness are factors that can contribute in establishing these expectations. The development of ICT in last decades and subsequently their massive use in society (particularly in scholar environment) offers completely new opportunities and perspectives. The aim of present thesis is to study the impacts of these technologies within situations when a relatively poor level of scholar achievements has like source a possible wrong estimation of teachers concerning the scholar potential of theirs students. We can say that by using these new technological achievements the school is finding in fact new tools for achieving its important mission. Currently, intensive efforts are made on studying how this completely new educational work environment and the particularities of these new techniques can influence teachers' regard on scholar's performances with positives effects on the self-esteem of the students or even on their scholar achievement. Trying to answer to some of these questions, the aim of present work is to study the screening effect of ICT, thus the possibility of using ICT to diminish the effects of teaching expectances on the scholar performances of the students. In this context, using ICT to hide the student identity seems to break the classical student teacher interaction
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Gherase, Dragos. "TADDOLs and derivatives : synthesis and applications in enantioselective processes." Thesis, Aix-Marseille 3, 2011. http://www.theses.fr/2011AIX30040.
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Dans cette thèse les résultats dans le domaine de la synthèse des dérivée des TADDOL et leur capacité d’induction chirale sont présentés. Une librairie des TADDOLs a été synthétisée et une analyse conformationnelle par VCD a été faite. Ces composés enantiopurs ont été testés dans la réaction de cyanosilylation enantioselective en donnant des résultats moyens. En partant de TADDOL nous avons synthétisé des dérivée phosphorés, des amines et des (thio)urées. Les dérivés de P(III) ont été utilisés comme ligands pour le palladium dans l’alkylation allylique asymétrique et les amines dans le réarrangement des époxydes meso. Les (thio)urées ont été testées pour leur capacité de complexation des anions carboxylatesIn this thesis are presented the results in the field of synthesis of TADDOL derivatives and their chiral induction capacity. A family of TADDOLs was synthesized and a conformational analysis was performed by VCD. These enantipure compounds were tested in enantioselective cyanosilylation reactions obtaining moderate results. Starting from TADDOL we obtained phosphorus derivatives, amines and (thio)ureas. The P(III) derivatives were tested as ligands for palladium in asymmetric allylic alkylation and the amines in the rearrangement of meso-epoxides. The (thio)ureas were screened for complexation capacity for carboxylate anions
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O'Donnell, John, and Jose Ramirez. "Design and Use of a CCSDS - Compatible Data Unit Decoder." International Foundation for Telemetering, 1994. http://hdl.handle.net/10150/611643.
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International Telemetering Conference Proceedings / October 17-20, 1994 / Town & Country Hotel and Conference Center, San Diego, CaliforniaThe Consultative Committee for Space Data Systems (CCSDS) formulates and publishes recommendations for space data system standards. CCSDS Recommendations define a layered data communications network along the lines of the OSI model. In the space link layer (OSI Data Link layer) fixed length blocks of CCSDS Packets are generated and multiplexed into the data field of Virtual Channel Data Units (VCDUs) in the Virtual Channel Access Sublayer. VCDUs with error correction coding become CVCDUs (coded VCDUs). CVCDUs (or VCDUs) with an attached sync marker become Channel Access Data Units (CADUs) which are transmitted on the Physical Space Channel. This paper discusses AYDIN's DEC012 Data Unit Decoder, a VMEbus circuit card which recovers Virtual Channel Data Units (VCDUs) from corrupted Channel Access Data Units (CADUs) received on the Space Link Subnet of a CCSDS-compatible space datacomm link. The module's design and operation is described along with its use in the X-ray Timing Explorer (XTE) and Tropical Rainfall Measuring Mission (TRMM) science satellite programs run by NASA Goddard Space Flight Center.
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Gercken, Martina [Verfasser], Daniel Peter [Verfasser] Franzen, and Wilhelm [Verfasser] Krone. "Klinische Studie zur elektrischen Therapie von Vorhofflimmern mittels R-Zacken gesteuerter Cardioversion versus Defibrillation (VCD-Studie) / Martina Gercken, Daniel Peter Franzen, Wilhelm Krone." Köln : Deutsche Zentralbibliothek für Medizin, 2019. http://d-nb.info/1196880506/34.
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Gercken, Martina [Verfasser], Daniel Peter Verfasser] Franzen, and Wilhelm [Verfasser] [Krone. "Klinische Studie zur elektrischen Therapie von Vorhofflimmern mittels R-Zacken gesteuerter Cardioversion versus Defibrillation (VCD-Studie) / Martina Gercken, Daniel Peter Franzen, Wilhelm Krone." Köln : Deutsche Zentralbibliothek für Medizin, 2019. http://d-nb.info/1196880506/34.
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Sen, Ananya. "Chiral recognition in neutral and ionic molecular complexes." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA112163/document.
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L'objectif principal de cette thèse est l’étude spectroscopique de molécules ou de complexes portant plusieurs centres chiraux en phase gazeuse, pour comprendre les effets de la stéréochimie sur leurs propriétés structurales. Des alcaloïdes dérivés de la Cinchonine ont été introduits intacts en phase gazeuse par ablation laser. Ils ont été étudiés en combinant un jet supersonique avec de la spectroscopie laser. Les deux pseudo-énantiomères Quinine et Quinidine ont montré des spectres électroniques et vibrationnels similaires, en accord avec leur structure similaire. Leurs propriétés en solution diffèrent davantage, comme le montrent les expériences de dichroïsme circulaire vibrationnel (VCD). Cette différence est encore plus marquée dans l’Hydroquinine et l’Hydroquinidine. Enfin la reconnaissance chirale a été étudiée dans des complexes ioniques dans un piège à ions. La stabilité des complexes formés entre S-camphre et les R et S-Alanine protonées indique une préférence homochirale. Cependant, l'énergie d'interaction calculée ainsi que les spectres IRMPD dans la région des empreintes digitales sont identiques. Le rôle des conformères plus hauts en énergie dans la reconnaissance chirale a été discutéThe main objective of this thesis is a spectroscopic study of molecules or complexes bearing multiple chiral centres in the gas phase, to understand the effects of stereochemistry on their structural properties. Neutral cinchona alkaloids have been introduced intact in gas phase by laser-ablation. They have been studied by combining supersonic expansion with laser spectroscopy. The two pseudo-enantiomers Quinine and Quinidine show similar electronic and vibrational spectra, in line with similar structure. Their properties in solution differ more, as shown by Vibrational Circular Dichroism (VCD) experiments. This difference is further enhanced in Hydroquinine and Hydroquinidine. Lastly chiral recognition has been studied in ionic complexes in an ion trap. A homochiral preference has been shown in the stability of the complexes formed between S-Camphor and R and S protonated Alanine. However, the calculated interaction energy as well as the IRMPD spectrum in the fingerprint region are identical. The role of higher energy conformers in chiral recognition has been discussed
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Laviolette, Laura. "The Effects of the Female Reproductive Hormones on Ovarian Cancer Initiation and Progression in a Transgenic Mouse Model of the Disease." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/19939.
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Ovarian cancer is thought to be derived from the ovarian surface epithelium (OSE), but it is often diagnosed during the late stages and therefore the events that contribute to the initiation and progression of ovarian cancer are poorly defined. Epidemiological studies have indicated an association between the female reproductive hormones and ovarian cancer etiology, but the direct effects of 17β-estradiol (E2), progesterone (P4), luteinizing hormone (LH) and follicle stimulating hormone (FSH) on disease pathophysiology are not well understood.
A novel transgenic mouse model of ovarian cancer was generated that utilized the Cre/loxP system to inducibly express the oncogene SV40 large and small T-Antigen in the OSE. The tgCAG-LS-TAg mice developed poorly differentiated ovarian tumours with metastasis and ascites throughout the peritoneal space. Although P4 had no effect; E2 significantly accelerated disease progression in tgCAG-LS-TAg mice. The early onset of ovarian cancer was likely mediated by E2’s ability to increase the areas of putative preneoplastic lesions in the OSE.
E2 also significantly decreased survival time in ovarian cancer cell xenografts. Microarray analysis of the tumours revealed that E2 mainly affects genes involved in angiogenesis and cellular differentiation, proliferation, and migration. These results suggest that E2 acts on the tumour microenvironment in addition to its direct effects on OSE and ovarian cancer cells.
In order to examine the role of the gonadotropins in ovarian cancer progression, the tgCAG-LS-TAg mice were treated with 4-vinylcyclohexene-diepoxide (VCD) to induce menopause. Menopause slowed the progression of ovarian cancer due to a change in the histological subtype from poorly differentiated tumours to Sertoli tumours.
Using a transgenic mouse model, it was shown that E2 accelerated ovarian cancer progression, while P4 had little effect on the disease. Menopause (elevated levels of LH and FSH) altered the histological subtype of the ovarian tumours in the tgCAG-LS-TAg mouse model. These results emphasize the importance of generating animal models to accurately recapitulate human disease and utilizing these models to develop novel prevention and treatment strategies for women with ovarian cancer.
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Bünnemann, Karoline [Verfasser], Christian [Gutachter] Merten, Stefan M. [Gutachter] Huber, and Rochus [Gutachter] Schmid. "Lösungsmitteleffekte auf die IR und VCD Spektren kleiner chiraler Modellverbindungen und supramolekularer Strukturen / Karoline Bünnemann ; Gutachter: Christian Merten, Stefan M. Huber, Rochus Schmid ; Fakultät für Chemie und Biochemie." Bochum : Ruhr-Universität Bochum, 2020. http://d-nb.info/1202609023/34.
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Dörl, Maria, Jonathan Kurz, and Alexander Clauss. "Kritischer Perspektivenwechsel im virtuellen Klassenzimmer: Charakteristika einer erfolgreichen virtuellen Zusammenarbeit aus Studierendensicht." TUDpress, 2019. https://tud.qucosa.de/id/qucosa%3A36590.
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Arbeitsbedingungen verändern sich immer deutlicher, insbesondere im Bereich der Wissensarbeit. Die moderne Informations- und Kommunikationstechnologie (IKT) führt zu einem Bedeutungsverlust zentraler, lokal begrenzter Arbeitsplätze. Gleichzeitig gewinnt die Fähigkeit zur Zusammenarbeit in dezentralen, interkulturellen, interdisziplinären Teams an Bedeutung (Perez-Sabater, Montero-Fleta, MacDonald, & Garcia-Carbonell, 2015). Neben inhaltsbezogenen Fachkompetenzen gewinnen dadurch Sozial-, Selbst-, Medien- und Methodenkompetenzen in Unternehmen an Relevanz (Kummer, Wolff, Lieske, & Schoop, 2012). Die Vorbereitung der Studierenden auf diese veränderten Arbeitsbedingungen ist eine entscheidende Herausforderung für die Hochschulen (Coyne, 2008). [... aus der Einleitung]
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Mogg, Sebastian. "Long-Wavelength Vertical-Cavity Lasers : Materials and Device Analysis." Doctoral thesis, KTH, Microelectronics and Information Technology, IMIT, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3585.
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Vertical-cavity lasers (VCLs) are of great interest as lightsources for fiber-optic communication systems. Such deviceshave a number of advantages over traditional in-plane laserdiodes, including low power consumption, efficient fibercoupling, on-chip testability, as well as potential low-costfabrication and packaging. To date, GaAs-based VCLs operatingat 850 nm are the technology of choice for short-distance,high-speed data transmission over multimode fiber. Forlong-distance communication networks, long-wavelength (LW) VCLsoperating in the 1.3 and 1.55-μm transmission windowsof standard singlemode fibers are desired. However, despiteconsiderable worldwide development efforts, the commercialbreakthrough of such devices has still to be achieved. This ismainly due to shortcomings of the intrinsic material propertiesof InP-based material systems, traditionally employed in LWlaser diodes. While LW quantum well (QW) active regions basedon InP are well established, efficient distributed Braggreflectors (DBRs) are better built up in the AlGaAs/GaAsmaterial system. Therefore, earlier work on LW VCLs has focusedon hybrid techniques such as bonding between InP-based QWs andAlGaAs/GaAs DBRs using waferfusion. More recently, however, themain interest in this field has shifted towards all-epitaxialGaAs-based devices employing novel 1.3-μm activematerials with strained GaInNAs QWs as one of the mostpromising candidates.
The main focus of this thesis is on the characterization andanalysis of LW VCLs and building blocks thereof, based on bothInP and GaAs substrates. This includes a theoretical study on1.3-μm InGaAsP/InP multiple QW active regions, as wellas an experimental investigation of novel, highly strained1.2-μm InGaAs/GaAs single QWs. Two high-accuracyabsolute reflectance measurement setups were built for thecharacterization of various DBRs. Reflectance measurementsrevealed that n-type doping is much more detrimental to theperformance of AlGaAs/GaAs DBRs than previously anticipated.Near-room temperature operation of a single-fused1.55-μm VCL with an InP/InGaAsP bottom DBR wasobtained. A thermal analysis of this device structure clearlyindicated its limited capabilities in terms of high-temperatureoperation. As a result, further efforts were directed towardsall-epitaxial GaAs-based VCLs. Record-long emission wavelengthsto above 1260 nm were obtained from InGaAs VCLs based on anextensive gaincavity detuning. These devices showed verypromising performance characteristics in terms of thresholdcurrent and light output power, indicating good potential forbeing a viable alternative to GaInNAs-based VCLs.
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Radtke, Oliver, and Markus Kellgren. "3D-visualisering i mark- och anläggningsprojekt. : En studie utifrån Veidekkes förutsättningar att implementera 3D-modeller i produktion." Thesis, Högskolan i Halmstad, Akademin för ekonomi, teknik och naturvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-40451.
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Samhällsdigitaliseringen har lett till att byggbranschen mer och mer strävar efter att digitalisera verktyg och arbetssätt. Att presentera projekt i 3D har därför blivit ett hett ämne där flera aktörer strävar efter att både projektera och nyttja 3D ute i produktionen. Tidigare forskning inom ämnet har till största del valt att lägga fokus på byggskedet och belyser de fördelar som går att utvinna genom nyttjandet av så kallade VDC- eller BIM verktyg. Samtidigt belyser andra vetenskapliga rapporter mark och anläggning som ett betydelsefullt skede inom hela byggprocessen. Ett flertal menar också att mark- och anläggningsskedet spelar en huvudroll i huruvida ett byggprojekt når framgång eller inte. Med detta i åtanke upplever författarna att 3D-modeller i mark- och anläggningsprojekt inte utforskats till den grad som känns nödvändig för att belysa fördelarna, men även de olika hinder som står i vägen för en lyckad implementeringsprocess. Det råder inte heller några tvivel om att byggskedet kommit längre i digitala utvecklingsaspekter, så som att visualisera projekt i 3D, vid en jämförelse med mark och anläggning. I denna studie belyser därför författarna de fördelar som går att utvinna genom att visualisera mark- och anläggningsprojekt i 3D. Studien visar upp bevis på varför verktyget bör implementeras och vad aktörer bör tänka på vid en eventuell implementering av 3Dvisualisering i projekt. Syftet med studien är därav att utreda hur det undersökta fallföretaget kan integrera 3D-modeller i mark- och anläggningsprojekt, samt belysa vilka krav fallföretagets anställda ställer på en 3D-modell för att främja utvecklingen av ett verktyg som passar och leder till en hög nyttjandegrad ute i produktionen. Vidare sker en identifiering av vilka förutsättningar ute i mark och anläggningsprojekt som spelar en nyckelroll i huruvida en implementerad 3D-modell skall kunna figurera och verka så som det är tänkt. Studien utförs med en kvalitativ metod där granskning av befintlig litteratur lyfter fram de problemområden som författarna identifierat. Vidare utförs semistrukturerade intervjuer med tjänstemän och yrkesarbetare på fallföretaget Veidekke Entreprenad AB. Intervjuerna genomförs i syfte att identifiera aktuella problem ute i produktionen, undersöka respondenternas syn på 3D-modeller samt belysa verktygets potentiella inverkan på deras vardagliga arbete. En tydligt övergripande slutsats är att 3D-modeller i allra högsta grad behövs ute i produktionen på mark- och anläggningsprojekt. Mycket pekar på att verktyget bland annat skulle bidra med en ökad förståelse kring utförandet av projekten, men också förbättra kommunikation och produktionsledande. Verktyget kan också enligt studien minimera problemområden gällande tekniska lösningar, förbättra planering, samt genom att digitalisera moment även tillfredsställa arbetsglädjen för produktionsteamet.Due to the digitalization the construction business is increasingly striving against more digitized tools and working methods. Presenting projects in 3D has therefore become a hot topic where several actors are trying to implement 3D not only in the design phase but also in the production phase. Earlier research dealing with the subject largely chooses to focus on the building construction process and highlights the advantages that can be extracted using so called VDC- or BIM tools. Some of the scientific reports reviewed during this study on the other hand, highlights the importance of the infrastructure and earthworks stages as a part of the entire construction process. Many also believe that the infrastructure and earthworks stage play a key role in whether a construction project achieve success or not. With that in mind, the authors feel that 3D-models for infrastructure and earthworks, have not yet been explored to the extent that feels necessary, meaning that the advantages and the various obstacles that stand in the way of a successful implementation process needs to be investigated. There is no doubt that building construction has come further in a digital development aspect of visualizing projects in 3D, compared to infrastructure and earthworks. In this study the authors have highlighted the benefits that can be gained by visualizing infrastructure and earthworks projects in 3D. The study also shows evidence of why the application of such should take place and what companies should be considering when implementing 3D visualization into such projects. The purpose of the study is therefore to investigate how the company researched by the authors can integrate 3D models into their infrastructure and earthworks projects. This in addition to identifying the requirements that the employees have on a 3D model to facilitate development of a tool that fulfils these requirements and is usable in production. In addition, the conditions and requirements that play a main role in infrastructure and earthworks projects have been investigated to identify the most suitable conditions to allow the model to work in the most efficient way as possible. The study is conducted with a qualitative method including an examination of existing literature that highlights the problem areas identified by the authors. In addition, semi structured interviews are carried out with employees from the work-site leadership and the skilled workers at the company Veidekke Entreprenad AB. This to identify the current problem areas in the production of infrastructure and earthworks projects and to examine employees’ view about how 3D models would impact on their everyday work. A clear overall conclusion is that 3D-models are truly needed in infrastructure and earthworks projects out in production. A lot of factors indicate that the tool would, among other things, contribute to an increased understanding of the scope of projects and thus contribute to an improved communication and production process leading. Such a tool can according to this study, also minimize problem areas regarding technical solutions, contribute to a better planning, and by digitizing processes, increase job satisfaction for the site team.
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Drummer, Jens. "Einfluss verschiedener Typen online basierter Lernplattformen auf die Kompetenz– und Leistungsentwicklung von Schülern." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1232884068861-14322.
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Online basierte Lernplattformen sind an Universitäten und Hochschulen im Bereich der Lehre weitestgehend eingeführt. An Schulen werden diese Lernplattformen ebenfalls immer mehr genutzt. Bei der Nutzung von online basierten Lernplattformen verspricht man sich eine Reihe von Verbesserungen im Bereich der Selbstlernkompetenzen. In der vorliegenden Arbeit wird untersucht, in welcher Form Lernangebote auf der Basis von Lernplattformen über das Internet für Schüler bereitgestellt werden können und welche Konsequenzen sich für den Aufbau der Lernplattformen ergeben, wenn diese in der Schule eingesetzt werden. Parallel hierzu wird untersucht, wie stark sich die Selbstlernkompetenz der Schüler während der Nutzung von online basierten Lernplattformen verändert. Damit eine Zuordnung der entwickelten Szenarien zu den jeweiligen Lernplattformen vereinfacht wird, wurde ein Diagramm in der Form eines Fünfeckes entwickelt. Dieses Diagramm wird als didaktisches Pentagramm in der Arbeit eingeführt und verwendet. Bei der Nutzung der Lernplattformen wird die Möglichkeit der Kollaboration zwischen den Nutzern (Lehrende und Lerner) als Klassifikationskriterium aus der Sicht eines Lerners eingeführt. Daraus ergeben sich zwei Typen von Lernplattformen: - Primär kollaborative Systeme (PKS) bzw. Gruppenlernsysteme, bei denen die Kollaboration einen wesentlichen Bestandteil des Wissenserwerbs darstellt und - Sekundär kollaborative Systeme (SKS) bzw. Individuallernsysteme, bei denen eine Kollaboration mit anderen Lernern in den Hintergrund rückt. Der Einsatz der Lernplattformen wird zum einen durch einen Fragebogen zum anderen durch die Messung der Leistungsentwicklung im Vergleich zu Testgruppen ohne die Nutzung von online basierten Lernplattformen erfasst. Aus diesen Ergebnissen heraus werden allgemeine technische Anforderungen an Lernplattformen abgeleitet. Durch die Umsetzung dieser Forderungen soll sichergestellt werden, dass bei einem Einsatz der Lernplattformen im schulischen Bereich ein optimaler Lernerfolg erreicht werden kann. Es wird nachgewiesen, dass für Einsatz von online basierten Lernplattformen bei Lernern mit einer gering ausgeprägten Selbstlernkompetenz eine Steuerung des Lernweges notwendig ist. In diesem Fall führt der Einsatz von online basierten Lernplattformen des Types SKS zu einer Verbesserung der Lernleistung. Der kollaborative Ansatz unter Nutzung eines primär kollaborativen Systems bzw. Gruppenlernsystems führt bei den Testgruppen zwar zu einer Verbesserung der Selbstlernkompetenz, hierbei können jedoch keine Verbesserungen von Lernleistungen gegenüber dem klassischen Lehransatz nachgewiesen werden. ---- <img src="http://vg01.met.vgwort.de/na/532892aa69654092b591f5531a8bf22c" width="1" height="1" alt=""/>
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Sen, Ananya. "Reconnaissance chirale dans des complexes moléculaires neutres et ioniques." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00829098.
Full textAbstract:
L'objectif principal de cette thèse est l'étude spectroscopique de molécules ou de complexes portant plusieurs centres chiraux en phase gazeuse, pour comprendre les effets de la stéréochimie sur leurs propriétés structurales. Des alcaloïdes dérivés de la Cinchonine ont été introduits intacts en phase gazeuse par ablation laser. Ils ont été étudiés en combinant un jet supersonique avec de la spectroscopie laser. Les deux pseudo-énantiomères Quinine et Quinidine ont montré des spectres électroniques et vibrationnels similaires, en accord avec leur structure similaire. Leurs propriétés en solution diffèrent davantage, comme le montrent les expériences de dichroïsme circulaire vibrationnel (VCD). Cette différence est encore plus marquée dans l'Hydroquinine et l'Hydroquinidine. Enfin la reconnaissance chirale a été étudiée dans des complexes ioniques dans un piège à ions. La stabilité des complexes formés entre S-camphre et les R et S-Alanine protonées indique une préférence homochirale. Cependant, l'énergie d'interaction calculée ainsi que les spectres IRMPD dans la région des empreintes digitales sont identiques. Le rôle des conformères plus hauts en énergie dans la reconnaissance chirale a été discuté.
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Drummer, Jens. "Einfluss verschiedener Typen online basierter Lernplattformen auf die Kompetenz– und Leistungsentwicklung von Schülern." Doctoral thesis, Technische Universität Dresden, 2008. https://tud.qucosa.de/id/qucosa%3A23846.
Full textAbstract:
Online basierte Lernplattformen sind an Universitäten und Hochschulen im Bereich der Lehre weitestgehend eingeführt. An Schulen werden diese Lernplattformen ebenfalls immer mehr genutzt. Bei der Nutzung von online basierten Lernplattformen verspricht man sich eine Reihe von Verbesserungen im Bereich der Selbstlernkompetenzen. In der vorliegenden Arbeit wird untersucht, in welcher Form Lernangebote auf der Basis von Lernplattformen über das Internet für Schüler bereitgestellt werden können und welche Konsequenzen sich für den Aufbau der Lernplattformen ergeben, wenn diese in der Schule eingesetzt werden. Parallel hierzu wird untersucht, wie stark sich die Selbstlernkompetenz der Schüler während der Nutzung von online basierten Lernplattformen verändert. Damit eine Zuordnung der entwickelten Szenarien zu den jeweiligen Lernplattformen vereinfacht wird, wurde ein Diagramm in der Form eines Fünfeckes entwickelt. Dieses Diagramm wird als didaktisches Pentagramm in der Arbeit eingeführt und verwendet. Bei der Nutzung der Lernplattformen wird die Möglichkeit der Kollaboration zwischen den Nutzern (Lehrende und Lerner) als Klassifikationskriterium aus der Sicht eines Lerners eingeführt. Daraus ergeben sich zwei Typen von Lernplattformen: - Primär kollaborative Systeme (PKS) bzw. Gruppenlernsysteme, bei denen die Kollaboration einen wesentlichen Bestandteil des Wissenserwerbs darstellt und - Sekundär kollaborative Systeme (SKS) bzw. Individuallernsysteme, bei denen eine Kollaboration mit anderen Lernern in den Hintergrund rückt. Der Einsatz der Lernplattformen wird zum einen durch einen Fragebogen zum anderen durch die Messung der Leistungsentwicklung im Vergleich zu Testgruppen ohne die Nutzung von online basierten Lernplattformen erfasst. Aus diesen Ergebnissen heraus werden allgemeine technische Anforderungen an Lernplattformen abgeleitet. Durch die Umsetzung dieser Forderungen soll sichergestellt werden, dass bei einem Einsatz der Lernplattformen im schulischen Bereich ein optimaler Lernerfolg erreicht werden kann. Es wird nachgewiesen, dass für Einsatz von online basierten Lernplattformen bei Lernern mit einer gering ausgeprägten Selbstlernkompetenz eine Steuerung des Lernweges notwendig ist. In diesem Fall führt der Einsatz von online basierten Lernplattformen des Types SKS zu einer Verbesserung der Lernleistung. Der kollaborative Ansatz unter Nutzung eines primär kollaborativen Systems bzw. Gruppenlernsystems führt bei den Testgruppen zwar zu einer Verbesserung der Selbstlernkompetenz, hierbei können jedoch keine Verbesserungen von Lernleistungen gegenüber dem klassischen Lehransatz nachgewiesen werden. ---- <img src="http://vg01.met.vgwort.de/na/532892aa69654092b591f5531a8bf22c" width="1" height="1" alt=""/>
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Cedrón, Juan Carlos. "Métodos para determinar la configuración absoluta de una molécula." Revista de Química, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/99434.
Full textAbstract:
Determinar la configuración absoluta de las moléculas quirales representa un gran reto para los químicos orgánicos. Para conseguir este objetivo existen diversas técnicas, las cuales se describen en el presente trabajo, así como ejemplos de cómo han sido utilizadas para la determinación de la configuración absoluta de productos naturales.Methods for the assignment of the absolute configuration of an organic molecule: The assignment of the absolute configuration of chiral molecules represents a great challenge for organic chemists. There are several techniques in order to establish it, and they are described in this work, as well as examples of how they can be applied in the assignment of the absolute configuration of natural products.
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Bautista, Harold H. 1979. "Performance analysis of different voltage controlled delay lines in a delay-locked loop." Thesis, 2012. http://hdl.handle.net/2152/ETD-UT-2012-05-5416.
Full textAbstract:
Bus interfaces keep getting faster and thus requiring designers to build custom physical fabrics that are able to delay clock and(or) data, on their transmitter and receivers, in order to properly receive and send data with enough setup and hold times. Delay locked loops (DLLs) have become fundamental building blocks that address such problems. Not only are they present in physical layers in integrated circuits but they also solve the problem of VLSI systems that suffer from clock skew and jitter. This report focuses on the implementation of a standard DLL and three different voltage controlled delay topologies. The different topologies are designed and compared for metrics such as linearity, delay range, and sensitivity to power supply.text
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Góbi, Sándor. "Flexibilis molekulák és molekulakomplexek vizsgálata VCD spekroszkópiával." Doctoral thesis, 2018. http://hdl.handle.net/10316/47415.
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Adamec, Martin. "Komponenty VCL pro vektorovou grafiku ve výuce chemie." Master's thesis, 2006. http://www.nusl.cz/ntk/nusl-265909.
Full textAbstract:
Předmětem práce je zhodnocení problematiky vzorců ve výuce organické chemie na střední škole, zhodnocení současného stavu softwaru pro kreslení chemických struktur a vývoj VCL komponent pro chemické kreslení. V současnosti dostupný software je na vysoké odborné úrovni a v chemické praxi má široké použití, nehodí se však pro použití ve výuce na druhém a třetím stupni. Výsledkem práce jsou komponenty pro vytváření, zobrazení a manipulaci s chemickými vzorci jednoduchých organických látek v souladu s požadavky střední školy Součástí práce je také aplikace ukazující základní vlastnosti vyvinutých komponent. Kom- ponenty i aplikace jsou vytvořeny v prostředí Borland Delphi 2005. CD s elektronickou verzí textu, zdrojovými kódy komponent i aplikace a spustitelnou verzí aplikace je přiloženo.
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SU, PO-JUI, and 蘇柏睿. "VCDC: An Efficient Trust Value Collection Mechanism for Trust Management in MANET." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/03038379549776479516.
Full textAbstract:
碩士國立臺灣科技大學
資訊管理系
99
As the world modernizes nowadays, change of the society, and the popular use of mobile internet device by almost every human being. Consequently, there are more and more user nodes take part in mobile ad hoc networks. On the other hand, the security problems of mobile ad hoc networks have been suffering from a severe challenge. However, security methods used to deal with traditional problems can not directly be used on MANETs environment. It is obviously that people need a robust system to guard networks against wicked attacks. Then, how to build trust among nodes is the key to prevent the adversary from launching a successful attack. In recent years, trust management framework has drawn many researchers’ attentions to this field. Trust management framework provides a high-level consideration of security policy and management, and this framework is used comprehensively for misbehavior detection, secure routing protocol, and key management and extends to access control, e-commerce, data aggregation, and even researching potential threats in mobile ad hoc networks. In trust management framework, node requires absorbing the other nodes’ opinions to improve the robustness of this framework. However, nodes periodically exchange their direct observation to each others, which consumes more bandwidth even generates a traffic jam. Whereas, it is not objective when node only adopts its neighbors’ direct observation, and narrows the detection rate of misbehaved nodes. In this thesis, we present a new method called virtual cluster data collection method (VCDC) for reactive collecting second-hand information rapidly in trust management framework. At first, user node sorts neighbor nodes according to the node density they observed with a common ways. Next, calculate covariance value between two nodes in the sorting order, then according to covariance value, dividing neighbor nodes into k groups. Last, choose an inheritor from a specific group to take over the following works. We also conduct simulations based on three key factors, and it shows that our method is very suitable for high-density mobile ad hoc networks and will be a powerful tool to assist nodes gathering useful information.
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Shin-Bang, Chen, and 陳信邦. "VCD Protocol for Transaction Management in Composite Web Services." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/86490969408662208999.
Full textAbstract:
碩士國立中正大學
資訊管理學系
93
Web services are emerging as a promising technology for effectively integrating diverse applications. A composite web service is one that aggregates the functionality provided by web services. In order to transactional support, we may impose three specifications to accomplish transaction management on composite web services. However, these specifications bring additional communication cost to the overall transaction management in terms of coordination. Further, these specifications that may be used two-phase commit can lead to resource locked and wait for a long time. The proposed protocol can decrease communication cost and don’t adopt resource locking method.
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Chi-Chelin and 林祺哲. "VCD Bubble Improvement in Color-FilterProcess of G8.5 TFT-LCD Fabrication." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/99396508550396953590.
Full textAbstract:
碩士國立成功大學
工程科學系專班
100
Color filters are the major parts of LCD. In the study, the improvement is made on an abnormal issue of the color filter caused by the vacuum dry process, which is just behind the photo resist coating process. The abnormal issue is the formation of VCD bubbles. The VCD bubbles are mainly resulted from the too fast pressure change or the non-uniform air flow, which make tiny bubbles appear in the photoresist on the surface of the substrate. There are two ways to solve the VCD bubble problem. The first one is to adjust the composition of the photoresist. The other one is to improve the design of the equipment or tune the working parameters of equipment. In the engineering emergent treatment of the bubble issue, the common way is to adjust the vacuum flow rate, the height of glass in the chamber, or the proportion of vacuum pressures of different types. In the long-term treatment of the issue, the composition of the photoresist is adjusted. However, these two treatments are often ineffective. Besides the methods mentioned above, this study adds some new designs. For example, the number of chamber vacuum pipe is changed. Single vacuum pipe is added into the experimental investigation while there is only multi-pipe used in the old ways. The internal extract opening in the chamber is changed from the stationary type to the adjustable one. The quality characteristic of Smaller-The-Best of the Taguchi method is used to evaluate the experimental factors for reducing the defect rate of bubble and to obtain the optimal process conditions. The results of the study are expected to be helpful for the new design of the new generation equipment.
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Hsiang-ShengWu and 吳祥生. "Improvement on VCD Bubble Problems in G5 Process of Color Filter." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/44448972476599915675.
Full textAbstract:
碩士國立成功大學
工程科學系專班
101
TFT-LCD is a very important high-tech industry in Taiwan. The whole world TFT-LCD panels are almost provided by Taiwan, Japan and South Korea since 1990. Each panel manufacturer actively expanded the production capacity based on the conviction that the bigger the stronger. The expansion competition reached the apex before the financial tsunami of 2008 and then the average sale price stumbled endlessly. This let the manufacturers make more panels and lose more money and therefore the manufacturers stopped the competition. Instead of the capacity contest, the high tech, high specification, high ASP products are now on the way, such as IPS, IGZO, AHVA and high PPI products. The price of the 15.5 inch monitor with the high resolution of 320 PPI is 50% to 60% higher than that of the one with the normal resolution of 200 PPI. Consequently, under the precondition that the high PPI will become the main-stream specification, the customer will ask the stricter defect specification, especially the WP (white point) one. The main purpose of the thesis is to improve the VCD bubble problems in G5 process of color filter. Under the current equipment layout, the bubble problems are studied experimentally with the assistance of the Taguchi experiment method. It is expected that the modified method of zero VCD bubble and low cost could be found.
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梁俊傑. "Developing the Flaw Inspection Systemon on the Surface of VCD and DVD Disk." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/51265128839639901130.
Full textAbstract:
碩士國立屏東科技大學
機械工程系
90
The objective of this research was devoted to develop an automatic inspection system for detecting the flaws on the surface of VCD and DVD disk. A self-designed inspection system is divided into two subsystems including the “feeder-loading and sorter-loading” and the machine vision system. The main equipments of the present inspection system comprise a personal computer, a programmable motion controller, feeder/sorter mechanism and illumination light structure. The inspected disk was initially transported from feeder-loading to place at a rotary plate for further taking images. The disk was fixed by vacuum force and successively captured by two cameras for further detection of various flaws. The flaws of the present investigation including pinholes, scratch, oil stain and clouds were effectively recognized by using the frame processing of image Subtraction, blobs analysis and morphology method. The experimental results indicate that if the flaw area is larger than 0.026mm2, the investigated flaws are completely detected.
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Bernstein, Sarah Mae. "Improving differential diagnosis of vocal cord dysfunction." Thesis, 2014. http://hdl.handle.net/2152/25870.
Full textAbstract:
Purpose: The purpose of this study was to assess whether the factors historically presented in the literature to differentiate vocal cord dysfunction (VCD) from breathing difficulties of other etiologies accurately predict and identify patients who have VCD. The researchers were also interested in whether patients with VCD have a higher risk of misdiagnosis than patients with breathing difficulties of other etiologies. Finally, the present study investigated whether patients with VCD were more likely to have their symptoms attributed to psychological factors than patients with breathing difficulties of other etiologies.
Method: A survey comprised of 23 questions regarding the participants’ previous and current diagnoses, triggers that precede breathing difficulty, and whether or not the participants have ever been misdiagnosed was posted to internet support groups, websites, blogs, and forums. The final participant pool included 20 participants with VCD and 25 participants with asthma.
Results: None of the factors investigated accurately differentiated participants with asthma from participants with VCD one hundred percent of the time. However, participants with VCD were more likely to report throat tightness during an attack, association of an attack with symptoms of acid reflux, and rapid resolution of symptoms without treatment. Conversely, participants with asthma were more likely to report expiratory stridor and chest tightness, full resolution of symptoms with use of asthma medications, nocturnal symptoms or symptoms just after waking, and symptoms that seemed to be triggered by environmental agents or allergens. Preliminary findings from the present study suggest that patients with VCD are both more likely to receive a misdiagnosis and have their symptoms attributed to psychological factors than participants with asthma.
Conclusion: A diagnosis of VCD must be made very carefully, ideally with instrumental evaluation of the vocal mechanism during an acute “attack” of breathing difficulty. The factors identified in the literature to differentially diagnose patients with asthma from patients with VCD do not accurately differentiate these populations. These findings suggest that continued education about the nature of VCD and differential diagnosis should be paramount to medical professionals.text
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Merten, Christian [Verfasser]. "Untersuchung der molekularen Konformation und der intermolekularen Wechselwirkung chiraler Verbindungen mittels VCD-Spektroskopie / von Christian Merten." 2010. http://d-nb.info/1007324635/34.
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LIN, WU HSIAO, and 巫曉玲. "The Compresion With Health Education VCD and Leaflet for Coronary Artery Disease Patient's Diet Cognition and Self-efficacy." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/83003738313564110432.
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碩士慈濟大學
護理學研究所
92
The purpose of this study is to make comparison of diet cognition and self-efficacy between health education VCD and leaflet for patients with coronary artery disease. The study used interventional experimental design on 70 cardiac patients from both cardiac intensive and regular care units at a medical center in Changhua. Subjects were devided into Group A and B. Subjects of Group A were arranged to watch health education VCD and then received pre and post test on health care knowledge for cardiac artery disease and self-efficacy for diet. Two weeks after they discharged from hospital, they had second post test on the same topics. Subjects of Group B given educational leaflets and received the same pre and post questionnaires. After the first post test, subject in Group B then watched the health education VCD, and received the second post-test two weeks after returning home from hospital. Findings of this study indicate that the implementation of teaching activity on “Health Education VCD” has helped improve the scores for cardiac artery disease patients’ diet cognition which was superior to that of Group B.Beside, the implementation of teaching activity on “Health Education VCD” has helped improve the scores for cardiac artery disease patients’ self-efficacy for diet control which is superior to that of Group B. For evaluating two weeks after discharged from hospital, there was a declined tendency on scores for Group A on diet cognition and self-efficacy. As watching “Health Education VCD” after the questionnaire evaluation, Group B has improved greatly on scores two weeks after which were superior to that pre and post the questionnaire evaluation. Furthermore, diet cognition was positively correlated with self-efficacy for diet. Findings from Stepwise Regression Analysis indicate that age, education, diet habit and group category of patients in this study would have effect on scores on diet cognition and self-efficacy for diet pre and post the questionnaire evaluation. Thes results show that teaching effect of VCD produced from model, images and demonstration is superior to that which takes leaflet as teaching tool. Meanwhile, nutrition education program can enhance the effect of case cognition and self-efficacy. Therefore, multiple media is one worthwhile health education measure which can work as reference for clinic nursing teaching in the future.
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"Variations in Menopause Etiology Affect Cognitive Outcomes: How Age, Menopause Type, and Exogenous Ovarian Hormone Exposures Across the Lifespan Impact the Trajectory of Brain Aging." Doctoral diss., 2019. http://hdl.handle.net/2286/R.I.54874.
Full textAbstract:
abstract: Reproductive hormones are recognized for their diverse functions beyond reproduction itself, including a vital role in brain organization, structure, and function throughout the lifespan. From puberty to reproductive senescence, the female is characterized by inherent responsiveness to hormonal cyclicity. For most women, a natural transition to menopause occurs in midlife, wherein the endogenous hormonal milieu undergoes significant changes and marks the end of the reproductive life stage. Although most women experience natural menopause, many women will undergo gynecological surgery during their lifetime, which can lead to an abrupt surgical menopause. It is of critical importance to better understand how endogenous and exogenous reproductive hormone exposures across the lifespan influence cognitive and brain aging, as women are at a greater risk for developing a variety of diseases after menopause, including dementia. Using rodent models, this dissertation explores how the etiology of reproductive senescence, that is, whether it is transitional or surgical, influences the female phenotype to result in divergent cognitive outcomes dependent upon a variety of factors, with an emphasis on age at the time of intervention playing a key role in brain outcomes. Furthermore, the impact of exogenous hormone therapy on cognition is evaluated in the context of surgical menopause. A novel rat model of hysterectomy is also presented, with results demonstrating for the first time that the nonpregnant uterus, which is typically considered to be a quiescent organ, may play a unique, direct role in modulating cognitive outcomes. Neurobiological mechanisms associated with reproductive hormones and aging are assessed to better recognize neural correlates underlying the observed behavior changes. The overarching goal of this dissertation was to elucidate novel factors contributing to cognitive aging outcomes in females. Collectively, the data presented herein indicate that the age at the onset of reproductive senescence has significant implications for learning and memory outcomes, and that variations in gynecological surgery can have unique, long-lasting effects on the brain and cognition. Translationally, this series of experiments moves the field forward toward the goal of improving the health and quality of life for women throughout the lifespan.Dissertation/Thesis
Doctoral Dissertation Psychology 2019
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Lakhmostova, Irina, Anna Leichsenring, Alexander Clauss, Anne-Katrin Haubold, and Eric Schoop. "Personalwirtschaft integrativ und virtuell." 2018. https://ul.qucosa.de/id/qucosa%3A33231.
Full textAbstract:
Das hochschulübergreifende Lehrangebot „Personalwirtschaft integrativ und virtuell“ steht für ein interaktives sowie flexibles Lernarrangement. Ziel des kooperativen Projektes zwischen den wirtschaftswissenschaftlichen Fakultäten der Technischen Universität Dresden (TU Dresden) und der Hochschule für Technik und Wirtschaft Dresden (HTW Dresden) ist die Realisierung eines lernerzentrierten,
integrativen und virtuellen Lehrkonzepts. Der vorliegende Beitrag fokussiert sich in diesem Zusammenhang auf die Darstellung des didaktischen Grundkonzeptes und damit einhergehend auf die Schaffung eines generischen Frameworks zur Übertragung auf ähnliche Lehr-/Lernszenarien in der Hochschullehre. Zudem werden die aus der Durchführung des kooperativen Lehr-Lern-Projektes resultierenden Herausforderungen und Potenziale im Sinne der Nachhaltigkeit und Verstetigung der Projektergebnisse für weiterführende Lehrangebote herausgearbeitet.
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Peters, Nils [Verfasser]. "Enantioselektive HPLC-Trennung und VCD-Strukturbestimmung von atropisomeren MeSO2-PCB sowie Studien über deren Toxizität und deren Verteilung in Biota-Proben / vorgelegt von Nils Peters." 2002. http://d-nb.info/966002849/34.
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