Relevant bibliographies by topics / Vecteur viraux

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Vecteur viraux'

Author: Grafiati
Published: 21 December 2024
Last updated: 31 July 2025

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Journal articles on the topic "Vecteur viraux"

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Tangy, Frédéric, and Jean-Nicolas Tournier. "Les virus au service de la santé : la vaccination." médecine/sciences 38, no. 12 (2022): 1052–60. http://dx.doi.org/10.1051/medsci/2022168.

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Depuis plus de deux siècles, les virus sont utilisés, avec un succès impressionnant, comme outils de prévention des infections virales. Depuis la variole et la rage, l’histoire de la vaccinologie a suivi les pas de l’histoire de la virologie. Après les découvertes empiriques des premiers vaccins, le développement du génie génétique, de la virologie moléculaire, de la génétique inverse, la manipulation des génomes viraux, leur séquençage à haut débit et leur synthèse chimique, la maîtrise de la culture cellulaire et des méthodes de purification, ont considérablement contribué au développement d
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Bertagnoli, Stéphane. "Actualité sur les vecteurs vaccinaux viraux." Bulletin de l'Académie Vétérinaire de France, no. 1 (2017): 22. http://dx.doi.org/10.4267/2042/62249.

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Chouchan, Dominique. "Thérapie Génique: Loin des vecteurs viraux." Biofutur 1997, no. 166 (1997): 11. http://dx.doi.org/10.1016/s0294-3506(97)86766-x.

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BERTAGNOLI, S., B. PIGNOLET, S. BIACCHESI, et al. "Les vecteurs viraux : outils modernes de vaccination." INRAE Productions Animales 21, no. 1 (2008): 127–36. http://dx.doi.org/10.20870/productions-animales.2008.21.1.3383.

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Les vaccins destinés aux animaux appartiennent à deux grandes catégories : les vaccins à agents vivants, et ceux à agents inertes. Depuis quelques années, dans chacune de ces catégories, les innovations technologiques ont considérablement amélioré et diversifié les stratégies vaccinales disponibles en fonction des contraintes liées à des préoccupations tant d’innocuité, que d’efficacité ou encore de nature économique. C’est dans ce cadre que l’INRA a depuis de nombreuses années orienté les efforts de recherche vers l’élaboration de nouveaux vaccins s’appuyant sur la mise au point de vecteurs v
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Legendre, JY, J. Haensler, and JS Rémy. "Les vecteurs non-viraux de thérapie génique." médecine/sciences 12, no. 12 (1996): 1334. http://dx.doi.org/10.4267/10608/675.

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Quéméneur, Éric. "Les vecteurs viraux en immunothérapie du cancer." Annales des Mines - Réalités industrielles Novembre 2023, no. 4 (2023): 87–91. http://dx.doi.org/10.3917/rindu1.234.0087.

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Par leurs propriétés uniques, les vecteurs viraux sont incontournables en thérapie génique ou pour l’ingénierie des thérapies cellulaires. Leur usage direct en tant qu’agent d’immunothérapie antitumorale, soit sous la forme de virus oncolytique ou comme vaccin thérapeutique, fait encore l’objet d’importants travaux de recherche et développement. L’approbation de T-Vec en 2015 a dopé le domaine des oncolytiques et près d’une vingtaine de produits sont en cours d’évaluation clinique. Les vecteurs non réplicatifs bénéficient de l’engouement général pour la vaccination thérapeutique et de l’arrivé
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Peschanski, M. "Tyrosine hydroxylase : trois vecteurs viraux pour un gène." médecine/sciences 11, no. 3 (1995): 474. http://dx.doi.org/10.4267/10608/2231.

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Manus, Jean-Marie. "Anémie de Fanconi : vecteurs viraux pour essai de thérapie génique." Revue Francophone des Laboratoires 2020, no. 518 (2020): 10. http://dx.doi.org/10.1016/s1773-035x(20)30011-3.

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Fontenille, D., and C. Paupy. "Vecteurs et environnement pour support de l’émergence virale." Médecine et Maladies Infectieuses 38 (June 2008): S27—S29. http://dx.doi.org/10.1016/s0399-077x(08)72980-9.

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Martinent, E., and M. Zawati. "Le virage numérique comme vecteur d’égalité (territoriale) en santé (I)." Ethics, Medicine and Public Health 15 (October 2020): 100593. http://dx.doi.org/10.1016/j.jemep.2020.100593.

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Dissertations / Theses on the topic "Vecteur viraux"

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Link, Peggy. "Identification des déterminants viraux responsables de la spécificité de transmission du Grapevine fanleaf virus par son nématode vecteur Xiphinema index." Université Louis Pasteur (Strasbourg) (1971-2008), 2005. http://www.theses.fr/2005STR13140.

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Le Grapevine fanleaf virus (GFLV) est responsable de la maladie du court-noué de la vigne qui affecte près de 30 % du vignoble français et n’épargne pas les autres pays viticoles. Ce virus est spécifiquement transmis par le nématode Xiphinema index et son génome est constitué de deux ARN simple brin de polarité positive. Mon travail de thèse a porté sur l’identification des déterminants viraux responsables de la spécificité de transmission du GFLV par Xiphinema index. Des travaux préalables ont montré que ces résidus étaient situés sur l’ARN2, plus précisément au niveau des 9 aminoacides C-ter
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BRUYERE, ARNAUD. "Etude des determinants viraux impliques dans la transmission du beet western yellows virus (bwyv) par son vecteur, le puceron myzus persicae." Strasbourg 1, 1997. http://www.theses.fr/1997STR13128.

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Le beet western yellows virus ou bwyv est un luteovirus, qui infecte de tres nombreuses dicotyledones d'interet agronomique et provoque des jaunisses caracteristiques. Ce virus, limite aux tissus phloemiens de la plante hote, est transmis par un puceron, myzus persicae, selon le mode persistant et circulant. La capside de ce virus est constituee de deux proteines : une proteine majeure ou proteine de coque (cp) de 22,5 kda, codee par l'orf 3 et une proteine mineure ou proteine de readthrough (rt) de 74 kda. Cette proteine de rt est exprimee a partir des orf 3 et 5 grace a un mecanisme de trans
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Marchand, Maia. "Ingénierie chimique de la capside du vecteur viral adéno-associé par bioconjugaison et chimie click bioorthogonale." Electronic Thesis or Diss., Nantes Université, 2024. http://www.theses.fr/2024NANU1031.

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Le virus adéno-associé (AAV) est un vecteur de choix pour la thérapie génique in vivo grâce à sa capacité à transduire une grande majorité de tissus avec une faible immunogénicité. Bien que huit traitements utilisant l’AAV aient obtenu une autorisation de mise sur le marché en Europe et/ou aux États- Unis, certaines limitations, comme son large tropisme, restreignent son utilisation clinique. Afin d’augmenter sa spécificité tissulaire, nous avons développé une stratégie combinant bioconjugaison et chimie click bioorthogonale. Cette approche permet une fonctionnalisation rapide et efficace de l
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Cottard, Virginie. "Développement et utilisation de vecteurs viraux et cellulaires en thérapie génique anti-inflammatoire : application à un modèle de polyarthrite rhumatoïde." Paris 7, 2003. http://www.theses.fr/2003PA077029.

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Avenel, Allan. "Caractérisation et immunomodulation de la réponse cellulaire contre les produits de thérapie génique." Electronic Thesis or Diss., Nantes Université, 2024. http://www.theses.fr/2024NANU1028.

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Les virus adéno-associés recombinants (rAAV) plus prévalent avec 45% de positivité, suivi de l'AAV8 sont des outils efficaces pour le transfert de gènes in vivo, (24%). De plus, l'évaluation du profil d’expression avec 8 médicaments approuvés par la FDA ou l'EMA aux cytokinique _ a permis de montrer des différences de États-Unis et en Europe. Cependant, il reste des fonctionnalité des lymphocytes anti-AAV8 et anti-AAV9. obstacles majeurs à surmonter pour que leur application Afin de mettre en évidence ces différences, jai développé lini é un protocole permettant d’enrichir la très rare populat
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BELIN, CHRISTOPHE. "Recherche des determinants viraux impliques dans la transmission du virus du court-noue de la vigne (gflv) par son vecteur, le nematode xiphinema index." Université Louis Pasteur (Strasbourg) (1971-2008), 1999. http://www.theses.fr/1999STR13078.

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Le grapevine fanleaf nepovirus (gflv) et l'arabis mosaic nepovirus (armv) sont les agents de la maladie du court-noue de la vigne. Malgre une tres forte identite de sequence, gflv et armv sont transmis specifiquement par les nematodes xiphinema index et x. Diversicaudatum. Le genome de ces virus est reparti sur deux arn qui codent pour deux polyproteines. L'arn-1 assure la replication des arn et code pour la proteinase 1d#p#r#o qui mature les polyproteines. L'arn-2 est responsable de la specificite de vecteur ; il code pour la proteine 2a necessaire a sa replication et pour les proteines de mo
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Vaysse, Laurence. "Développement de vecteurs non viraux pour le transfert de gène dans l'épithélium respiratoire." Bordeaux 2, 2000. http://www.theses.fr/2000BOR28795.

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Doucet, Gilles. "Les vecteurs viraux pour le développement de thérapies géniques ex vivo dans les cellules du muscle squelettique humain." Master's thesis, Université Laval, 2007. http://hdl.handle.net/20.500.11794/19481.

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Venail, Frédéric. "Transfert d'ADN dans la cochlée de mammifère par vecteur adénoviral : mise au point technique vers un modèle de régénération de l'organe de Corti utilisant l'interférence ARN." Montpellier 1, 2008. http://www.theses.fr/2008MON1T024.

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Les surdités de perception résultent principalement de la destruction des cellules neurosensorielles de la cochlée, partie de l'oreille interne dédiée à l'audition. Ces pertes sont irréversibles chez le mammifère, car les cellules ciliées détruites ne sont pas renouvelées à partir de leurs cellules de soutien comme chez les oiseaux ou les reptiles. Chez ces animaux, la régénération des cellules ciliées est étroitement liée à la régulation de la cycline p27kip1. Le but de ce travail était de déterminer si l'inhibition de p27kip1 pouvait entraîner une division et une différenciation des cellules
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Léger, Psylvia. "Etude comparée de l'infection de cellules de l'hôte mammifère et de cellules du vecteur moustique par le virus de la Fièvre de la Vallée du Rift." Paris 7, 2009. http://www.theses.fr/2009PA077073.

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Le Virus de la Fièvre de la Vallée du Rift (VFVR) est un virus appartenant à la famille des Bunyaviridae et au genre Phlebovinis. Cet arbovirus, transmis par les moustiques, infecte l'homme et les ruminants et est à l'origine de nombreuses épidémies/épizooties. Le segment S utilise une stratégie ambisens afin de coder la nucléoprotéine N ainsi que la protéine non structurale NSs. Bien que le cycle viral soit exclusivement cytoplasmique, NSs forme des filaments nucléaires. Cette protéine est à l'origine d'au moins deux mécanismes délétères lors de l'infection de cellules de mammifère. En intera
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Books on the topic "Vecteur viraux"

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Julien, Jennifer. Le clônage de la protéine virale CrmA dans un vecteur d'expression. Université Laurentienne, 2000.

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L, Hefferon Kathleen, ed. Virus expression vectors. Transworld Research Network, 2007.

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Mukhopadhyay, S. Plant virus, vector epidemiology and management. Science Publishers, 2010.

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Mukhopadhyay, S. Plant virus, vector epidemiology and management. Science Publishers, 2010.

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Mukhopadhyay, S. Plant virus, vector epidemiology and management. Science Publishers, 2010.

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T, Plumb R., ed. Plant virus vector interactions. Academic Press, 2002.

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Chan, C. K. Aphid-transmitted viruses and their vectors of the world. Research Branch, Agriculture Canada, 1991.

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International Symposium on Viruses with Fungal Vectors (1987 St. Andrews University). Viruses with fungal vectors. Association of Applied Biologists, 1988.

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C, Asher M. J., Cooper J. I, and Association of Applied Biologists, eds. Viruses with fungal vectors: Proceedings of a conference at the University of St. Andrews, 25-27 August, 1987. Association of Applied Biologists, 1988.

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Danielová, Vlasta. Relationships of mosquitoes to Ťahyňa virus as determinant factors of its circulation in nature. Academia, Publishing House of the Czechoslovak Academy of Sciences, 1992.

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Book chapters on the topic "Vecteur viraux"

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Conzelmann, Karl-Klaus. "Reverse Genetics of Mononegavirales: The Rabies Virus Paradigm." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_1.

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Nagai, Yoshiyuki, and Atsushi Kato. "Sendai Virus Biology and Engineering Leading up to the Development of a Novel Class of Expression Vector." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_2.

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Iida, Akihiro, and Makoto Inoue. "Concept and Technology Underlying Sendai Virus (SeV) Vector Development." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_3.

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Wiegand, Marian, and Wolfgang J. Neubert. "Genome Replication-Incompetent Sendai Virus Vaccine Vector Against Respiratory Viral Infections That Is Capable of Eliciting a Broad Spectrum of Specific Immune Response." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_4.

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Seki, Sayuri, and Tetsuro Matano. "Development of Vaccines Using SeV Vectors Against AIDS and Other Infectious Diseases." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_5.

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Yonemitsu, Yoshikazu, Yasuji Ueda, and Mamoru Hasegawa. "BioKnife, a Modified Sendai Virus, to Resect Malignant Tumors." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_6.

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Fusaki, Noemi, and Hiroshi Ban. "Induction of Human Pluripotent Stem Cells by the Sendai Virus Vector: Establishment of a Highly Efficient and Footprint-Free System." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_7.

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Yonemitsu, Yoshikazu, Takuya Matsumoto, and Yoshihiko Maehara. "Gene Therapy for Peripheral Arterial Disease Using Sendai Virus Vector: From Preclinical Studies to the Phase I/IIa Clinical Trial." In Sendai Virus Vector. Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_8.

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Díaz-Menéndez, Marta, and Clara Crespillo-Andújar. "The Vector." In Zika Virus Infection. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59406-4_4.

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Gulhan, Baris. "Biological Methods Used in Gene Therapy." In Gene Therapy. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358824.3.

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Gene therapy is used to prevent or treat genetic diseases. To treat genetic diseases, transfer of genes that correct the effects of the mutation that causes the disease to the patient. In gene therapy, the therapeutic gene is transferred to target cells through a vector and viral vectors are most used. Retroviruses (lentiviruses), adenoviruses, adeno-associated viruses, and herpes virus vectors are common as viral vectors. In this section, biological methods used especially in gene therapy stages examined.
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Conference papers on the topic "Vecteur viraux"

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Mintaev, R. R., D. V. Glazkova, O. V. Orlova, F. A. Urusov, G. A. Shipulin, and E. V. Bogoslovskaya. "DEVELOPMENT OF THE TECHNOLOGY PLATFORM BASED ON THE MODIFIED VACCINIA ANKARA FOR RAPID PRODUCTION OF VECTOR VACCINES." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-194.

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Infectious diseases, including viral diseases, are a major cause of death and disability. Vaccination is the most effective means of protection, but the efficacy and safety of vaccines are often unsatisfactory. The aim of this study is to develop methods for the rapid production of immunogenic MVA-based vector vaccines against RNA viruses. We created candidate vaccines against influenza virus and against dengue virus based on MVA vector.
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Ryabova, E. I., A. A. Derkaev, M. A. Dovgiy, et al. "DELIVERY OF TETRAMERIZED SINGLE-DOMAIN ANTIBODY GENES USING A RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR TO INDUCE PROTECTION AGAINST INFLUENZA A VIRUS AND SARS-COV-2 VIRUS." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-98.

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Influenza A and SARS-CoV-2 viruses continue to pose a serious threat to public health. In our study we obtained a recombinant adeno-associated viral vector expressing the gene of tetramerized single-domain antibodies specific to various variants of the SARSCoV-2 virus and influenza A viruses. It was shown that a single intramuscular administration of the obtained vector provides protection against influenza A infection and COVID-19 in a prophylactic mode.
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Al-Shehab, Usmaan, Maduka Gunasinghe, Yousuf Elkhoga, Nimay Patel, and Juliana Yang. "Cardiovascular Disease Prediction Modelling: A Machine Learning Approach." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.109_2023.

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The objective of this project is to utilize the UCI Heart Disease dataset to identify physiological biomarkers that are highly correlated with heart disease incidence. A predictive model can then be developed using these biomarkers to estimate the likelihood of someone having or developing a heart-related condition. This study compares the efficacy of predicting cardiovascular disease as an outcome using three machine learning algorithms: Support Vector Machine, Gaussian Naive Bayes, and logistic regression. Support Vector Machine works by creating hyperplanes between data points to conduct cl
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Araujo, Carlos Soares, Marco Cristo, and Rafael Giusti. "Predicting Music Popularity on Streaming Platforms." In Simpósio Brasileiro de Computação Musical. Sociedade Brasileira de Computação - SBC, 2019. http://dx.doi.org/10.5753/sbcm.2019.10436.

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Online streaming platforms have become one of the most important forms of music consumption. Most streaming platforms provide tools to assess the popularity of a song in the forms of scores and rankings. In this paper, we address two issues related to song popularity. First, we predict whether an already popular song may attract higher-than-average public interest and become “viral”. Second, we predict whether sudden spikes in public interest will translate into long-term popularity growth. We base our findings in data from the streaming platform Spotify and consider appearances in its “Most-P
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Mueller, Melanie, Ralf Amann, Thomas Feger, and Hans-Georg Rammensee. "Abstract A170: The mode of action of Orf virus – a novel viral vector for therapeutic cancer vaccines." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-a170.

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Tomilova, Yulia, Yulia Khvorostova, Mikhail Ivanov, et al. "Complex PCR-diagnostics of respiratory infections in A children's hospital." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24027t.

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Background: Accurate differential etiological diagnosis allows to select the right therapy or adjust the course of treatment. The aim of the study was to analyze the etiological structure of childhood respiratory infections of viral and bacterial origin using the PCR method. Methods and Objectives: Nasoropharyngeal swabs of children admitted to hospital with symptoms of respiratory disease were examined (n=1443). The analysis was carried out using kits for DNA/RNA extraction and PCR kits "RealBest" (AO "Vector-Best"), designed to detect DNA/RNA of influenza A and B viruses, parainfluenza types
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Nurpeisova, Ainur, Zhandos Abay, Kamshat Shorayeva, et al. "Determining optimal conditions for growing recombinant vectors to be used in developing a bovine tuberculosis vaccine." In Research for Rural Development 2023 : annual 29th international scientific conference proceedings. Latvia University of Life Sciences and Technologies, 2023. http://dx.doi.org/10.22616/rrd.29.2023.013.

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Two recombinant influenza A virus vectors expressing the ESAT 6 and TB10.4 mycobacterial proteins from the nonstructural (NS) gene were constructed via reverse genetics technique to develop a specific means of prophylaxis for bovine tuberculosis. We experimented to determine optimal conditions for growing recombinant vectors in Vero cell culture and chick embryos. This study established that the maximum amount of virus builds up in a Vero cell culture with the Dulbecco′s Modified Eagle′s Medium (DMEM) serum-free medium. However, using cell culture to produce vector vaccines is labourintensive
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MIRON, Liviu-Dan, and Larisa IVĂNESCU. "The risk of vector-borne zoonotic disease transmission in the context of global warming." In "Instruire prin cercetare pentru o societate prosperă", conferinţă ştiinţifico-practică internaţională. Ion Creangă Pedagogical State University, 2024. https://doi.org/10.46727/c.v1.16-17-05-2024.p17-25.

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The incidence of mosquito-borne diseases varies geographically, with the transmission period potentially changing in response to the constant interaction between pathogens, hosts, vectors, and the environment with climate warming. In Iași County and the Great Brăila Island, 9 mosquito species have been identified: Aedes albopictus, Culex pipiens, Aedes caspius, Culex modestus, Aedes vexans, Anopheles maculipennis, Anopheles hyrcanus, Coquillettidia richardii, Culiseta anulata. Based on the temperatures developed in Romania, the risk of vector-borne diseases transmission was calculated: West Ni
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Lessa, Ruan Teixeira, Daniel Pedrosa Cassiano, Yasmin Jawhari da Silva, et al. "Epidemiological study on hospitalizations for viral encephalitis in Brazil between january 2010 to december 2020." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.561.

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Introduction: Viral encephalitis (VE) is an inflammation of the brain parenchyma that progresses to neurological dysfunction of infectious origin. It occurs after hematogenous dissemination into the Central Nervous System and the most common agents are herpes virus, influenza, enterovirus, arbovirus, cytomegalovirus and Epstein-Barr. The signs and symptoms are headache, fever, decreased level of consciousness, seizures, focal deficits and behavioral changes. Objective: Recognize the epidemiological pattern of hospitalizations for VE in Brazil, between 2010 and 2020. Methods: A search for origi
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Chisholm, Paul Joseph. "Competition with non-vectors mediates virus-vector interactions." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.115741.

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Reports on the topic "Vecteur viraux"

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Ullman, Diane, James Moyer, Benjamin Raccah, Abed Gera, Meir Klein, and Jacob Cohen. Tospoviruses Infecting Bulb Crops: Evolution, Diversity, Vector Specificity and Control. United States Department of Agriculture, 2002. http://dx.doi.org/10.32747/2002.7695847.bard.

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Objectives. The overall goal of the proposed research was to develop a mechanistic understanding of tospovirus evolution, diversity and vector specificity that could be applied to development of novel methods for limiting virus establishment and spread. Our specific objectives were: 1) To characterize newly intercepted tospoviruses in onion, Hippeastrum and other bulb crops and compare them with the known tomato spotted wilt virus (TSWV) and its isolates; 2) To characterize intra- and interspecific variation in the virus transmission by thrips of the new and distinct tospoviruses. and, 3) To d
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Mawassi, Munir, and Valerian V. Dolja. Role of the viral AlkB homologs in RNA repair. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7594396.bard.

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AlkB proteins that repair DNA via reversing methylation damage are conserved in a broad range of prokaryotes and eukaryotes including plants. Surprisingly, AlkB-domains were discovered in the genomes of numerous plant positive-strand RNA viruses, majority of which belong to the family Flexiviridae. The major goal of this research was to reveal the AlkB functions in the viral infection cycle using a range of complementary genetic and biochemical approaches. Our hypotheses was that AlkB is required for efficient replication and genetic stability of viral RNA genomes The major objectives of the r
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Mawassi, Munir, Adib Rowhani, Deborah A. Golino, Avichai Perl, and Edna Tanne. Rugose Wood Disease of Grapevine, Etiology and Virus Resistance in Transgenic Vines. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7586477.bard.

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Rugose wood is a complex disease of grapevines, which occurs in all growing areas. The disease is spread in the field by vector transmission (mealybugs). At least five elongated-phloem- limited viruses are implicated in the various rugose wood disorders. The most fully characterized of these are Grapevine virus A (GV A) and GVB, members of a newly established genus, the vitivirus. GVC, a putative vitivirus, is much less well characterized than GV A or GVB. The information regarding the role of GVC in the etiology and epidemiology of rugose wood is fragmentary and no sequence data for GVC are a
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Ullman, Diane E., Benjamin Raccah, John Sherwood, Meir Klein, Yehezkiel Antignus, and Abed Gera. Tomato Spotted Wilt Tosporvirus and its Thrips Vectors: Epidemiology, Insect/Virus Interactions and Control. United States Department of Agriculture, 1999. http://dx.doi.org/10.32747/1999.7573062.bard.

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Objectives. The major aim of the proposed research was to study thrips-TSWV relationships and their role in the epidemiology of the virus with the aim of using this knowledge to reduce crop losses occurring due to epidemics. Our specific objectives were: To determine the major factors involved in virus outbreaks, including: a) identifying the thrips species involved in virus dissemination and their relative role in virus spread; b) determining the virus sources among wild and cultivated plants throughout the season and their role in virus spread, and, c) determining how temperature and molecul
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Antignus, Yehezkiel, Ernest Hiebert, Shlomo Cohen, and Susan Webb. Approaches for Studying the Interaction of Geminiviruses with Their Whitefly Vector Bemisia tabaci. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604928.bard.

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The DNA of tomato yellow leaf curl virus (TYLCB) was detected in its whitefly vector, Bemisia tabaci, by dot spot hybridization as early as 1 h after acquisition access. The retention of the virus nucleic acid in the vector was at least 23 days after a 48 h acquisition access. However, the retention of TYLCV coat protein did not exceed 10 days. No replicative forms of TYLCV could be detected in B. tabaci, indicating a non-propagative relationship with the vector. Whiteflies were not able to accumulate naked virion ssDNA, virus cloned dsDNA, or virions with impaired coat protein. Deletion, fram
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Grubman, Marvin J., Yehuda Stram, Peter W. Mason, and Hagai Yadin. Development of an Empty Viral Capsid Vaccine against Foot and Mouth Disease. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570568.bard.

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Foot-and-mouth disease (FMD), a highly infectious viral disease of cloven-hoofed animals, is economically the most important disease of domestic animals. Although inactivated FMD vaccines have been succesfully used as part of comprehensive eradication programs in Western Europe, there are a number of concerns about their safety. In this proposal, we have attempted to develop a new generation of FMD vaccines that addresses these concerns. Specifically we have cloned the region of the viral genome coding for the structural proteins and the proteinase responsible for processing of the structural
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Mawassi, Munir, Baozhong Meng, and Lorne Stobbs. Development of Virus Induced Gene Silencing Tools for Functional Genomics in Grapevine. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7613887.bard.

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Grapevine is perhaps the most widely grown fruit crop. To understand the genetic make-up so as to improve the yield and quality of grapes and grape products, researchers in Europe have recently sequenced the genomes of Pinot noir and its inbred. As expected, function of many grape genes is unknown. Functional genomics studies have become the major focus of grape researchers and breeders. Current genetic approaches for gene function studies include mutagenesis, crossing and genetic transformation. However, these approaches are difficult to apply to grapes and takes long periods of time to accom
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Hernández Guzmán, Anngie Katherine, Diana Marcela Torres Jiménez, and Olga Yanet Pérez Cardona. Effect of the acquisition access period, retention period and inoculation access period on transmission efficiency of Potato yellow vein virus by Trialeurodes vaporariorum. Corporación Colombiana de Investigación Agropecuaria - AGROSAVIA, 2013. http://dx.doi.org/10.21930/agrosavia.poster.2013.1.

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El virus de la vena amarilla de la papa (PYVV) (Crinivirus / Closteroviridae), es un virus de planta reemergente, que se extendió en todas las áreas de de producción de papa colombiana PYVV, este es transmitido por el invernadero de mosca blanca (Trialeurodes vaporariorum) de semipersistente. Para la implementación de estrategias efectivas para PYVV / T. y el control de vaporariorum es necesaria la información sobre la relación entre el virus y su vector. En el presente estudio se detalla la transmisión de PYVV, se presentan las características de T. vaporariorum, la adquisición del período de
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Siriyasatien, Padet. Effect of double dengue serotypes infection in dengue mosquito (Aedes aegypti). Chulalongkorn University, 2012. https://doi.org/10.58837/chula.res.2012.19.

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We demonstrated the results of laboratory induced dengue virus infection more than 1 serotype in female Aedes aegypti through membrane feeding apparatus. Forty female mosquitoes were allowed to feed human blood contained 4 dengue serotypes at the concentration of 103 pfu/ml. One week after infection, dengue virus were detected by RT-PCR technique. Seven and two mosquitoes were positive for dengue serotype 3 and 4, respectively. Mix infection of dengue virus serotype 3 and 4 was found in 4 female mosquitoes. To determine the infectivity of dengue serotype 1 and 2, both serotypes were used to in
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Klement, Eyal, Elizabeth Howerth, William C. Wilson, et al. Exploration of the Epidemiology of a Newly Emerging Cattle-Epizootic Hemorrhagic Disease Virus in Israel. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7697118.bard.

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In September 2006 an outbreak of 'Bluetongue like' disease struck the cattle herds in Israel. Over 100 dairy and beef cattle herds were affected. Epizootic hemorrhagic disease virus (EHDV) (an Orbivirusclosely related to bluetongue virus (BTV)), was isolated from samples collected from several herds during the outbreaks. Following are the aims of the study and summary of the results: which up until now were published in 6 articles in peer-reviewed journals. Three more articles are still under preparation: 1. To identify the origin of the virus: The virus identified was fully sequenced and comp
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