Academic literature on the topic 'Vecuronium'

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Journal articles on the topic "Vecuronium"

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Wright, Peter M. C., Paul Hart, Marie Lau, et al. "The Magnitude and Time Course of Vecuronium Potentiation by Desflurane Versus Isoflurane." Anesthesiology 82, no. 2 (1995): 404–11. http://dx.doi.org/10.1097/00000542-199502000-00011.

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Background Preliminary studies suggest that desflurane and isoflurane potentiate the action of muscle relaxants equally. However, variability between subjects may confound these comparisons. A crossover study was performed in volunteers on the ability of desflurane and isoflurane to potentiate the neuromuscular effect of vecuronium, to influence its duration of action, and on the magnitude and time course of reversal of potentiation when anesthesia was withdrawn. Methods Adductor pollicis twitch tension was monitored in 16 volunteers given 1.25 MAC desflurane on one occasion, and 1.25 MAC isof
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Fisher, Dennis M., Janos Szenohradszky, Peter M. C. Wright, Marie Lau, Ronald Brown, and Manohar Sharma. "Pharmacodynamic Modeling of Vecuronium-induced Twitch Depression." Anesthesiology 86, no. 3 (1997): 558–66. http://dx.doi.org/10.1097/00000542-199703000-00007.

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Background After bolus doses of nondepolarizing muscle relaxants, the adductor pollicis recovers from paralysis more slowly than the diaphragm and the laryngeal adductors, suggesting that the adductor pollicis is more sensitive than the respiratory muscles to effects of those drugs. In contrast, during onset, the respiratory muscles are paralyzed more rapidly than the adductor pollicis, suggesting that the respiratory muscles are more sensitive than the adductor pollicis. To reconcile these apparently conflicting findings, we determined vecuronium's pharmacokinetics and its pharmacodynamics at
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Wright, Peter M. C., Gerald McCarthy, Janos Szenohradszky, Manohar L. Sharma, and James E. Caldwell. "Influence of Chronic Phenytoin Administration on the Pharmacokinetics and Pharmacodynamics of Vecuronium." Anesthesiology 100, no. 3 (2004): 626–33. http://dx.doi.org/10.1097/00000542-200403000-00024.

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Background The duration of action of vecuronium is reduced in patients receiving phenytoin. In this study, the authors examined, simultaneously, the influence of phenytoin on both the pharmacokinetics and the pharmacodynamics of vecuronium. Methods This study was approved by the institutional review board of the University of California, San Francisco, and patients gave written informed consent. Twenty-two patients, 11 taking phenytoin and all scheduled to undergo prolonged neurosurgical procedures with general anesthesia, participated in the study. In 12 patients (6 phenytoin, 6 control), vec
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Blobner, Manfred, Eberhard Kochs, Heidrun Fink, et al. "Pharmacokinetics and Pharmacodynamics of Vecuronium in Rats with Systemic Inflammatory Response Syndrome." Anesthesiology 91, no. 4 (1999): 999. http://dx.doi.org/10.1097/00000542-199910000-00020.

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Background Insufficient detoxification caused by nitric oxide-related inhibition of cytochrome P450 may be important for metabolism of numerous drugs, including vecuronium. The present study investigated the pharmacodynamics and pharmacokinetics of vecuronium in rats with inflammatory liver dysfunction. Methods Male Sprague-Dawley rats (n = 56) were randomly allocated into two groups: In the sepsis group, liver inflammation was established by injection of 56 mg/kg heat-killed Corynebacterium parvum; control rats received the solvent. At day 4, groups were subdivided according to treatment with
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Stirt, Joseph A., William Maggio, Charles Haworth, Michael D. Minton, and Robert F. Bedford. "Vecuronium." Anesthesiology 67, no. 4 (1987): 570–72. http://dx.doi.org/10.1097/00000542-198710000-00022.

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Beaufort, Ton M., Johannes H. Proost, Jan-Gerard Maring, Emiel R. Scheffer, J. Mark K. H. Wierda, and Dirk K. F. Meijer. "Effect of Hypothermia on the Hepatic Uptake and Biliary Excretion of Vecuronium in the Isolated Perfused Rat Liver." Anesthesiology 94, no. 2 (2001): 270–79. http://dx.doi.org/10.1097/00000542-200102000-00017.

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Background Hypothermia prolongs the time course of action of nondepolarizing muscle relaxants. It is not known whether this prolongation is caused by a reduced rate of extrahepatic distribution or elimination, liver uptake, metabolic clearance, or biliary excretion. Therefore, the authors studied the effects of hypothermia on the net hepatic uptake, metabolism, and biliary excretion of vecuronium in isolated perfused rat liver. Methods Livers of Wistar rats were perfused with Krebs Ringer solution (1% albumin, 3.3% carbon dioxide in oxygen, pH 7.36-7.42, 38 degrees C). Each perfusion experimen
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Reich, David L., Ingrid Hollinger, Donna J. Harrington, Howard S. Seiden, Sephali Chakravorti, and D. Ryan Cook. "Comparison of Cisatracurium and Vecuronium by Infusion in Neonates and Small Infants after Congenital Heart Surgery." Anesthesiology 101, no. 5 (2004): 1122–27. http://dx.doi.org/10.1097/00000542-200411000-00011.

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Background Neonates and infants often require extended periods of mechanical ventilation facilitated by sedation and neuromuscular blockade. Methods Twenty-three patients aged younger than 2 yr were randomly assigned to receive either cisatracurium or vecuronium infusions postoperatively in a double-blinded fashion after undergoing congenital heart surgery. The infusion was titrated to maintain one twitch of a train-of-four. The times to full spontaneous recovery of train-of-four without fade, extubation, intensive care unit discharge, and hospital discharge were documented after drug disconti
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&NA;. "Vecuronium bromide see Fentanyl/halothane/vecuronium bromide." Reactions Weekly &NA;, no. 367 (1991): 12. http://dx.doi.org/10.2165/00128415-199103670-00063.

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Larijani, Ghassem E., Irwin Gratz, Shahab S. Minassian, Deurward L. Hughes, Mary Afshar, and Basil N. Karayannis. "Comparative Evaluation of the Neuromuscular and Cardiovascular Effects of Pipecuronium, Pancuronium, Atracurium, and Vecuronium Under Isoflurane Anesthesia." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 12, no. 4 (1992): 278–82. http://dx.doi.org/10.1002/j.1875-9114.1992.tb04461.x.

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The neuromuscular and cardiovascular effects of intubating doses of pipecuronium 80 μg/kg, pancuronium 100 μg/kg, atracurium 500 μg/kg, and vecuronium 100 μg/kg were compared in 62 patients under isoflurane (end‐tidal concentration = 0.5–1%) anesthesia. Pipecuronium, pancuronium, and vecuronium had no significant effect on systolic or diastolic blood pressure. In one patient the administration of atracurium resulted in significant hypotension. Heart rate was significantly increased only after the administration of pancuronium. The neuromuscular‐blocking effect of pipecuronium and pancuronium a
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Wyon, Nicholas, Henning Joensen, Yuji Yamamoto, Sten G. E. Lindahl, and Lars I. Eriksson. "Carotid Body Chemoreceptor Function Is Impaired by Vecuronium during Hypoxia." Anesthesiology 89, no. 6 (1998): 1471–79. http://dx.doi.org/10.1097/00000542-199812000-00025.

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Background Neuromuscular blocking agents reduce the human ventilatory response to hypoxia at partial neuromuscular block. It was hypothesized that vecuronium impairs carotid body chemoreceptor function during hypoxia. Method The effect of systemic administration of vecuronium on single chemoreceptor activity during hypoxia, as recorded from a single nerve fiber preparation of the carotid sinus nerve, was studied in seven mechanically ventilated New Zealand White rabbits during continuous thiopental anesthesia. During normoventilation, the isocapnic hypoxic chemosensitivity of the single caroti
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Dissertations / Theses on the topic "Vecuronium"

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Nützel, Jakob. "Präkurarisierung mit Vecuronium inhibiert die Succinylcholinwirkung dosisabhängig." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963770780.

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SEGREDO, VERONICA. "Curarisation prolongee apres administration de vecuronium au long cours en reanimation." Nantes, 1992. http://www.theses.fr/1992NANT060M.

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Senotier, Jean-Marc. "Intubation rapide et curares non dépolarisants : contribution à l'étude du "priming" avec le vecuronium." Nantes, 1986. http://www.theses.fr/1986NANT3520.

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Dinsmore, Kristen G., Bethany Campbell, Timothy Archibald, Greg Mosier, Stacy D. Brown, and Alexei Gonzalez-Estrada. "Refrigerated Stability of Diluted Cisatracurium, Rocuronium, and Vecuronium for Skin Testing after Perioperative Anaphylaxis." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/5266.

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RATIONALE: The purpose of this study is to investigate the stored stability of dilutions of neuromuscular blocking agents (NMBAs), namely cisatracurium, rocuronium, and vecuronium, for skin prick/intradermal testing. METHODS: Concentrations of NMBAs were monitored by liquid chromatography-mass spectrometry (LC-MS/MS) for a period of 14 days. Dilutions of NMBAs were prepared in saline by factors of 10x, 100x, 1,000x, and 100,000x as sensitivity of the assay allowed. Diluted drug products were stored in a laboratory refrigerator until sampling. On sampling days, aliquots of each dilution were re
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Dinsmore, Kristen, Bethany Campbell, Timothy Archibald, Greg Mosier, Stacy PhD Brown, and Alexei MD Gonzalez-Estrada. "Refrigerated Stability of Diluted Cisatracurium, Rocuronium, and Vecuronium for skin testing after perioperative anaphylaxis." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/146.

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Rationale: The purpose of this study is to investigate the stored stability of dilutions of neuromuscular blocking agents (NMBAs), namely cisatracurium, rocuronium, and vecuronium, for skin prick/intradermal testing. Methods: Concentrations of NMBAs were monitored by liquid chromatography-mass spectrometry (LC-MS/MS) for a period of 14 days. Dilutions of NMBAs were prepared in saline by factors of 10x, 100x, 1,000x, 10,000x, and 100,000x as sensitivity of the assay allowed. Diluted drug products were stored in a laboratory refrigerator until sampling. On sampling days, aliquots of each dilutio
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Wyon, Nicholas. "On the interaction between a neuromuscular blocking agent and regulation of breathing during hypoxia /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-659-6.

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Castillejo, Correa Julio César. "Evaluación de secuencia inversa con vecuronio en pacientes sometidos a anestesia general." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2004. https://hdl.handle.net/20.500.12672/1777.

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EVALUACIÓN DE SECUENCIA INVERSA CON VECURONIO EN PACIENTES SOMETIDOS A ANESTESIA GENERAL EN EL HOSPITAL GUILLERMO ALMENARA IRIGOYEN. Dr. Julio César Castillejo Correa Hospital Guillermo Almenara Irigoyen. UNMSM Objetivo: Determinar como influye la secuencia de administración de Vecuronio en el tiempo, para lograr condiciones adecuadas de intubación en pacientes que reciben anestesia general. Metodología: Se diseño un estudio Experimental (Ensayo clínico), Prospectivo, Analítico, Longitudinal, Tipo Cohorte. La muestra incluyó 200 pacientes, que cumplieron los criterios de inclusión y fueron
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Early, Marvin E. "Comparison of Succinylcholine Induced Fasciculation Attenuation with Defasciculating Doses of Vecuronium and Mivacurium Based on Ideal Body Weight." VCU Scholars Compass, 1993. http://scholarscompass.vcu.edu/etd/4548.

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This study was conducted to determine if Mivacurium (Miv) was as effective as Vecuronium (Vec) in attenuating Succinylcholine (Sch)-induced fasciculations with muscle relaxant doses based upon ideal body weight (IBW). A quasi experimental design was used to study 60 patients who were randomly assigned to one of three groups. The two study groups were compared to a control group and each other with regards to the incidence and intensity of fasciculations. Either Vec (0.01 mg/kg (IBW)), Miv (0.02 mg/kg (IBW)), or saline (control) was administered in a double-blinded manner 3 minutes prior an int
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Kellner, Bernhard [Verfasser], Jürgen [Akademischer Betreuer] Schüttler, Jürgen [Gutachter] Schüttler, and Carla [Gutachter] Nau. "Die Muskelrelaxanzien Rocuronium, Vecuronium, Pancuronium, Atracurium und Succinylcholin aktivieren TRPA1 - und TRPV1 - Rezeptoren nozizeptiver Neurone / Bernhard Kellner ; Gutachter: Jürgen Schüttler, Carla Nau ; Betreuer: Jürgen Schüttler." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2020. http://d-nb.info/1204257841/34.

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Wiederkehr, Heinz. "Verteilung, Ausscheidung und Metabolismus von C-14-Vecuronium-Bromid nach i.v.-Applikation bei der Ratte : Beiträge zur Aufklärung der Pharmakokinetik und des Metabolismus eines Pancuronium-Analogon /." Zürich, 1985. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=7920.

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Books on the topic "Vecuronium"

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Kirchhübel, Martin. Die Wirkungsdauer von Alcuronium, Pancuronium und Vecuronium unter balancierter Anästhesie. [s.n.], 1988.

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Wiederkehr, Heinz. Verteilung, Ausscheidung und Metabolismus von ¹⁴C-Vecuronium-Bromid [C-Vecuronium-Bromid] nach i.v.-Applikation bei der Ratte: Beiträge zur Aufklärung der Pharmakokinetik und des Metabolismus eines Pancuronium-Analogon. [s.n.], 1985.

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Markreiter, Martin. Einflu¿ von Antihistaminika auf die Wirkdauer von Atracurium im Vergleich zu Vecuronium. 1990.

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Simões, Almeida Maria Cristina. Die Wirkung des Alters auf Anschlagszeit und Erholung nach Atracurium, Rocuronium und Vecuronium. 1996.

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Main, Universität Frankfurt am, ed. Der Einfluss von Desfluran auf die Wirkstärke der Muskelrelaxanzien Atracurium, Vecuronium und Pancuronium. 1998.

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Keienburg, Thomas. Der Einfluss einer Praecurarisierung mit Vecuronium, Pancuronium oder Atracurium auf das Wirkungsprofil von Succinylcholin. 1999.

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Gutenberg-Universität, Johannes, ed. Vergleichende Untersuchung zum Einfluss von Fentanyl und Sufentanil auf die Hämodynamik koronar herzkranker Patienten: Interaktionen mit Vecuronium. 1988.

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Rex, Christopher. Intubationsbedingungen nach Gabe von Atracurium und Vecuronium: Bolusinjektion versus Priming Prinzip ; eine prospektive, randomisierte, doppelblinde klinische Studie. 1994.

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Spemann, Barbara. Untersuchungen zum systemischen Einsatz des Muskelrelaxans Vecuronium bei Haustauben (Columba livia, var. domestica, Gmel., 1789) unter Luftsack-Perfusionsanästhesie. 1997.

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Raskin, Katrin. Modulation der Acetylcholin-Freisetzung aus dem Nervus phrenicus der Ratte durch präsynaptische Nikotin-Rezeptoren: Wirkung von (+)-Tubocurarin, Pancuronium, Atracurium und Vecuronium unter verschiedenen Stimulationsbedingungen. 1994.

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Book chapters on the topic "Vecuronium"

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Bowman, W. C., and G. A. Sutherland. "Vecuronium (ORG-NC-45)." In New Neuromuscular Blocking Agents. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70682-0_18.

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Miller, R. D. "Vecuronium (ORG-NC-45)." In New Neuromuscular Blocking Agents. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70682-0_28.

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Meretoja, Olli A., Larisa Jalkanen, Tomi Taivainen, Barbara W. Brandom, and Bimal Dayal. "Synergism Between Atracurium and Vecuronium with Mivacurium." In Muscle Relaxants. Springer Japan, 1995. http://dx.doi.org/10.1007/978-4-431-66896-1_62.

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Ottermann, U., and H. J. Schröder. "Interaktion von Vecuronium und Pancuronium — Klinische elektromyographische Untersuchungen." In Aktueller Stand der klinischen Anaesthesie. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71229-6_28.

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Redl, G., S. Schlöglhofer, C. K. Spiss, R. Riegler, J. Neumark, and V. Draxler. "Kombinationsanästhesie mit Propofol, Alfentanil und Vecuronium für mikrolaryngoskopische Eingriffe." In ZAK München 1987. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73573-8_12.

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Okuyama, Atsushi, Koichi Takita, and Osamu Kemmotsu. "The Duration of Vecuronium Action Shortened After Kidney Transplantation." In Muscle Relaxants. Springer Japan, 1995. http://dx.doi.org/10.1007/978-4-431-66896-1_87.

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Schultz, M., W. Friesdorf, T. Fösel, and K. H. Altemeyer. "Pharmakodynamik von Vecuronium beim Kleinkind nach intravenöser Narkoseeinleitung mit Ketamin." In Spezielle Anaesthesieprobleme. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71281-4_29.

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Nöldge, G., N. Krieg, G. Schomburg, B. Baumann, and K. L. Scholler. "Influence of Isoflurane on Muscle Relaxation with Vecuronium in Clinical Anesthesia." In Isoflurane. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71230-2_15.

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Nöldge, G., N. Krieg, B. Baumann, and K. L. Scholler. "Der Einfluß von Isofluran auf die Wirkungsstärke und den Wirkungsablauf von Vecuronium." In Aktueller Stand der klinischen Anaesthesie. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71229-6_27.

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Maestrone, E. "Heart Rate and Blood Pressure Changes After Vecuronium During NLA.A Preliminary Investigation." In Aktueller Stand der klinischen Anaesthesie. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71229-6_29.

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Conference papers on the topic "Vecuronium"

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McDaniel, Sullivan, Zhang, Hogan, and Wagner-Mann. "Influence Of Vecuronium Bromide On The ED50 For Electrical Ventricular Defibrillation In The Canine Model." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1992. http://dx.doi.org/10.1109/iembs.1992.595773.

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McDaniel, W. C., M. Sullivan, Q. Zhang, M. Hogan, and C. Wagner-Mann. "Influence of Vecuronium Bromide on the ED50 for electrical ventricular defibrillation in the canine model." In 1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1992. http://dx.doi.org/10.1109/iembs.1992.5761160.

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Reports on the topic "Vecuronium"

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Liao, Jian-Qiang, Darrell Shih, Tzu-Yu Lin, Meng Lee, and Cheng-Wei Lu. Appropriate dosing of sugammadex for reversal of rocuronium-/vecuronium-induced muscle relaxation in morbidly obese patients: a meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0130.

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Review question / Objective: To conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) to compare the effect of lower-dose sugammadex using IBW or CBW as dosing scalars, with that of standard-dose sugammadex based on TBW, on reversal time, defined as time to recovery of train of four ratio (TOFR) ≥ 0.9, among morbidly obese people after moderate or deep NMB with either rocuronium or vecuronium. Eligibility criteria: We included only randomized controlled trials (RCTs) that compared TBW with other dosing scalars for sugammadex. Studies not published in full text ar
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