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Dissertations / Theses on the topic 'Venous thrombosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Brown, John Gordon. "A study of deep venous thrombosis." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303015.

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2

Payne, Holly. "Novel insights into the mechanisms of venous thrombosis." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8172/.

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Venous thrombosis is a major health concern, with an annual incidence of ~1 per 1000 adults (Cushman 2007). This includes deep vein thrombosis (DVT) and pulmonary embolism (PE), the fatal consequence of a clot detaching and moving to the lungs, together these diseases are termed venous thromboembolism (VTE). Current treatment options for VTE are often associated with serious side effects and bleeding complications, highlighting the need for more effective prophylaxis. This study therefore aimed to identify new targets to treat DVT, which would not have the associated negative side effects. Thi

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3

Lindmarker, Per. "Treatment of deep vein thrombosis and risk of recurrent venous thromboembolism /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-3211-5/.

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4

Robins, Richard. "The role of vascular Gas6 in the pathophysiology of Venous Thrombosis." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114250.

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Gas6 is a vitamin K-dependent, secreted protein that amplifies platelet aggregation and secretion in response to platelet agonists. Gas6-/- mice are protected from experimentally induced lethal venous and arterial thromboembolism. This protection has been attributed to defective aggregation in platelets from Gas6-/- mice. However, this platelet phenotype was only observed when platelets were challenged by one agonist, ADP, and only at a concentration of 5.0 µM. This subtle platelet abnormality resulting in a rather dramatic clinical phenotype raises the possibility that Gas6 from a source othe

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5

Dai, Guohao 1970. "Computational and biological studies of mechanical prophylaxis against deep venous thrombosis." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/28236.

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Thesis (Ph. D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 2001.<br>Includes bibliographical references (p. 137-151).<br>Deep vein thrombosis (DVT) of the lower extremity and induced pulmonary embolism are common complications resulting from prolonged periods of bed-rest or immobilization of the limbs. One of the most effective methods of prophylaxis against DVT is external pneumatic compression (EPC). In spite of its wide acceptance as an effective means of prophylaxis, its mechanism remains poorly understood and optimal compression conditions

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6

Wilson, Stanley Darrin. "An investigation of lower limb venous function, whole blood coagulation and deep venous thrombosis following proximal femoral fracture." Thesis, Queen's University Belfast, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268218.

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7

Horner, Daniel. "Isolated distal deep vein thrombosis in symptomatic ambulatory patients : a prospective data analysis and therapeutic feasibility study." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/isolated-distal-deep-vein-thrombosis-in-symptomatic-ambulatory-patients-a-prospective-data-analysis-and-therapeutic-feasibility-study(02979c49-ec26-4099-b0f8-3da2acbf0672).html.

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Isolated distal deep vein thrombosis (IDDVT) is a condition recently suggested to be a different entity to that of proximal disease. There is currently little evidence defining the clinical importance of detection and treatment. International guidelines vary regarding management advice.An observational cohort study, prospective service evaluation and pilot randomised controlled trial were performed within a United Kingdom ambulatory thrombosis service. This project aimed to describe the burden of disease and explore three poorly researched aspects of IDDVT assessment and management: whole-leg

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8

Pazzini, Carla. "Preparação e caracterização de nanoparticulas com heparina e sua avaliação em modelo animal de trombose venosa." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310166.

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Orientadores: Joyce Maria Annichino-Bizacchi, Nelci Fenalti Hoher<br>Dissertação (mestrado) - Universidade Estadual de Campinas. Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-15T09:49:31Z (GMT). No. of bitstreams: 1 Pazzini_Carla_M.pdf: 2143259 bytes, checksum: b3ff6eb2527b691a4021526983ef2aeb (MD5) Previous issue date: 2010<br>Resumo: A heparina é um anticoagulante amplamente empregado no tratamento e profilaxia da trombose venosa profunda (TVP). Algumas limitações do seu uso são o custo e a via de administração, endovenosa ou subcutânea, às vezes em doses repetidas e

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9

Lapidus, Lasse. "Thromboembolism following orthopaedic surgery : outcome and diagnostic procedures after prophylaxis in lower limb injuries /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-111-1/.

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10

Andia, Kohnenkampf Marcelo. "Venous thrombosis : formation, evolution and resolution imaging using non-invasive MRI techniques." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/venous-thrombosis-formation-evolution-and-resolution-imaging-using-noninvasive-mri-techniques(99e7c5ac-77eb-4d0e-aad7-c90aa4202c79).html.

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Deep venous thrombosis (DVT) remains a major health problem. Although thrombolytic therapies are effective in recanalising the veins, restoring blood flow, preventing pulmonary embolism and post-thrombotic complications, there is still no consensus on the selection criteria for this invasive treatment. Experimental data suggest that thrombus rich in fibrin has better response to thrombolysis than red cell rich (acute phase) or collagen rich (chronic) thrombus. Thus, there is a need for a diagnostic technique that provides better information on the stage of thrombus organization in-vivo and all

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11

Vossen, Carolina Y. "Genetic risk factors for venous thrombosis : key players or minor risk modifiers ? /." [S.l. : s.n], 2005. http://catalogue.bnf.fr/ark:/12148/cb402235083.

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12

Svensson, Peter J. "Resistance to activated protein c a novel risk factor for venous thrombosis /." Lund : Dept. for Coagulation Disorders, Malmö University Hospital, Lund University, 1997. http://catalog.hathitrust.org/api/volumes/oclc/68945075.html.

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13

Duffett, Lisa. "Management of Superficial Venous Thrombosis: A Systematic Review of Literature and Survey of Canadian Physicians." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37105.

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Superficial venous thrombosis (SVT) is a common inflammatory and thrombotic pathology occurring within a superficial vein. SVT can result in distressing symptoms of redness and pain in the affected area and exposes patients to a risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE). Various therapeutic options are available to patients including anti-inflammatories, anti-coagulation and surgical procedures, however which of these therapies is the best first line treatment remains unknown. Several randomized controlled trials have been conducted addressing this question, yet

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14

Beauchamp, Nicholas James. "Molecular genetic basis of inherited thrombophilia." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287349.

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15

Sevestre-Pietri, Marie-Antoinette. "Réactualisation de modèles épidémiologiques et application à la maladie thromboembolique veineuse." Grenoble, 2010. http://www.theses.fr/2010GRENS042.

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La maladie thrombo-embolique veineuse est une entité hétérogène avec des formes cliniques de présentation et de pronostic variables. Compte tenu de l'évolution démographique de la population, de la grande diffusion d'outils diagnostiques fiables et de l'impact de la thromboprophylaxie, il nous a paru nécessaire de réactualiser les connaissances sur ce sujet. Trois études épidémiologiques ont permis les analyses de ce travail. Pour les sujets âgés en soins de suite lors d'une étude de type coupe transversale avec évaluation de type avant/après, nous avons montré que les patients âgés avaient de

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16

Flores-Nascimento, Mariane Cristina 1979. "Pesquisa de microparticulas plaquetarias circulantes em individuos com trombose venosa profunda, sindrome do anticorpo antifosfolipideo ou fator V de Leiden." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310164.

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Orientador: Joyce Maria Annicchi-Bizzacchi<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-09T02:14:05Z (GMT). No. of bitstreams: 1 Flores-Nascimento_MarianeCristina_M.pdf: 1784393 bytes, checksum: 7247759965458fc5957d9f5617c9fb7e (MD5) Previous issue date: 2007<br>Resumo: A Trombose Venosa Profunda (TVP) é uma doença multicausal, mas muitos fatores de risco ainda não estão definidos. Micropartículas (MPs) são pequenas vesículas liberadas da membrana celular durante ativação e apoptose. MPs podem ser um refle

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17

Opatrny, Lucie. "A case-control study examining the association between travel and deep venous thrombosis /." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82303.

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Background. This thesis explores the link between travel and deep venous thrombosis (DVT). While it is biologically plausible that prolonged travel is an independent risk factor for venous thromboembolic disease (VTE), epidemiological data to date are conflicting.<br>Aim. To determine whether there is a independent association between travel and DVT.<br>Methods. This was a multi-center case control study. Consecutive patients presenting to the vascular laboratory with clinically suspected DVT were eligible to participate. Cases were patients with confirmed DVT; controls were patients wh

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18

Aronen, Hannu J. "Imaging methods in the diagnosis of suspected deep venous thrombosis of the leg." Hki : Societas scientiarum Fennica, 1989. http://catalog.hathitrust.org/api/volumes/oclc/57854420.html.

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19

Rao, Deepa Prema. "The role of growth arrest-specific 6 in venous thromboembolism /." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112349.

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Background. Growth-arrest specific 6 (gas6) is a novel vitamin-K dependent protein whose role in venous thromboembolism was recently characterized in murine models. Gas6 is suggested to be a prothrombotic protein capable of mediating thrombus stability. However, the association between gas6 and venous thromboembolism has yet to be elucidated in humans. The present work aims to delineate the existence of such an association in humans and propose a mechanism by which gas6 expression is related to venous thromboembolic disease.<br>Methods. To analyze the association between gas6 and venous thromb

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20

Holmström, Margareta. "Clinical aspects on treatment of deep venous thrombosis with a low molecular weight heparin /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-2989-0/.

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21

Dörffler-Melly, Janine. "Experimental, clinical, and meta-analytical studies of antithrombotic therapies in venous and arterial thrombosis." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/59215.

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22

Al, Rawahi Bader. "Efficacy and Safety of Pharmacological Thromboprophylactic Agents for the Prevention of Venous Thromboembolism after Major Abdominal Surgery." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36050.

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Statement of the problem: The type and duration of pharmacological thromboprophylaxis post major abdominal surgery remains controversial. Methods of investigation: A systematic review and pooled analysis of literature was performed to assess the risk benefit ratio of the different pharmacological thromboprophylaxis agents compared to placebo or no thromboprophylaxis post major abdominal surgery. A survey of the clinical practice among both general surgeons and thrombosis expert was conducted. Results: The systematic review demonstrated that all five pharmacological thromboprophylaxis regimen

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23

Castellucci, Lana Antoinette. "Evaluating Risk of Delayed Major Bleeding in Critically Ill Trauma Patients." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/33442.

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Background: Up to 40% of trauma patients die during the first 24 hours after injury due to massive hemorrhage. In patients who survive this critical time period, no information is available on rates of delayed major bleeding or factors associated with delayed major bleeding. Methods: A retrospective chart review of 150 critically ill adult trauma patients was used to determine the incidence of delayed major bleeding events. Cox proportional hazards multivariate analysis was performed to assess for risk factors associated with delayed major bleeding events. The anticipated rate of delayed majo

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24

Smith, Sarah Faith. "Influences on the incidence of clinical deep vein thrombosis and pulmonary embolism in a prospectively collated population of 21,000 neurosurgical inpatients." Thesis, The University of Sydney, 2001. http://hdl.handle.net/2123/818.

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Records of all neurosurgical inpatients admitted to Royal North Shore Hospital since 1976 have been prospectively kept in a relational database. Demographic details, diagnoses, operations and complications have been entered continuously since 1982 by the author of this study. Complications are monitored at monthly review meetings attended by medical staff. The recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE) at these meetings, despite continual improvements in patient care, prompted this study. It aims to use the database to study changes in the incidence of DVT and PE

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Smith, Sarah Faith. "Influences on the incidence of clinical deep vein thrombosis and pulmonary embolism in a prospectively collated population of 21,000 neurosurgical inpatients." University of Sydney. Public Health and Community Medicine, 2001. http://hdl.handle.net/2123/818.

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Records of all neurosurgical inpatients admitted to Royal North Shore Hospital since 1976 have been prospectively kept in a relational database. Demographic details, diagnoses, operations and complications have been entered continuously since 1982 by the author of this study. Complications are monitored at monthly review meetings attended by medical staff. The recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE) at these meetings, despite continual improvements in patient care, prompted this study. It aims to use the database to study changes in the incidence of DVT and PE

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26

van, Rooijen Marianne. "Effects of combined oral contraceptives on hemostasis and biochemical risk indicators for venous thromboembolism and atherothrombosis /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-089-3/.

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27

Amini, Nekoo Ali. "Molecular analysis of human tissue factor pathway inhibitor (TFPI) gene in relation to venous thrombosis." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427717.

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28

Cheung, Katharine Lana. "Chronic Kidney Disease and the Risk of Venous Thromboembolism." ScholarWorks @ UVM, 2018. https://scholarworks.uvm.edu/graddis/879.

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Chronic kidney disease (CKD) affects more than 30 million adults in the U.S. and is strongly associated with cardiovascular events and mortality. Venous thromboembolism (VTE) is the third leading vascular disease, affects up to 900,000 Americans each year and contributes to as many as 100,000 deaths annually. The relationship of CKD and VTE has been described in patients receiving dialysis, kidney transplants recipients and in nephrotic syndrome, however, data supporting the association of VTE in mild to moderate CKD is conflicted. The overall goal of this research was to study the association

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29

Ikesaka, Rick. "The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/41954.

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Venous thromboembolism (VTE) is a common disorder which causes significant morbidity and mortality. Upper extremity deep vein thrombosis(UEDVT) is a relatively understudied subtype of VTE which is commonly associated with central venous catheters, cancer, and thrombophilia. The goal of this project was to better characterize the risk of UEDVT and to design and execute a pilot study that will demonstrate the efficacy of a strategy preventing the occurrence of VTE in a high-risk population for UEDVT. This M.Sc project, was conducted in three parts. Chapter 1 of the thesis outlines a sy

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Alessio, Aline Morandi. "Associação dos polimorfismos nos genes dos receptores alfa e beta do estrogeno em pacientes com trombose venosa profunda." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311375.

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Orientador: Nelci Fenalti Hoehr, Joyce M. Anichino-Baizzacchi<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-06T11:11:48Z (GMT). No. of bitstreams: 1 Alessio_AlineMorandi_M.pdf: 5240817 bytes, checksum: f759b9c995ffcb5198175f672d2a40aa (MD5) Previous issue date: 2005<br>Resumo: o estrógeno atua na hemostasia promovendo efeitos pró e antitrombóticos, sua ação ocorre através de sua ligação a receptores nucleares específicos, denominados receptores 'alfa' e 'beta' do estrógeno (RE). A presença de polimorfismos

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Flores-Nascimento, Mariane Cristina 1979. "Identificação de proteínas diferencialmente expressas em pacientes com trombose venosa profunda." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310154.

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Orientador: Joyce Maria Annichino-Bizzacchi<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-20T22:19:23Z (GMT). No. of bitstreams: 1 Flores-Nascimento_MarianeCristina_D.pdf: 2045016 bytes, checksum: 26506f3c6c426ff227cd481188662275 (MD5) Previous issue date: 2011<br>Resumo: A trombose venosa profunda (TVP) é uma doença multifactorial, e possui uma alta taxa de morbi-mortalidade devido a complicações como embolia pulmonar e a síndrome póstrombótica, e cerca de 25 % dos pacientes apresentarão recorrência em 5 anos. A

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32

Antovic, Aleksandra. "Determinations of the overall haemostasis potential and fibrin gel permeability : method development and application in research and in clinical materials /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-932-3/.

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33

Karevaara, Anette. "Komplikationer hos patienter med PICC." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-213215.

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SAMMANFATTNING Bakgrund: PICC är en central infart som används inom vården för att kunna ge kärlretande läkemedel. Komplikationer vid användning av PICC kan vara infektion, trombos, tromboflebit eller stopp i katetern. Syfte: Syftet med studien är att undersöka förekomsten av komplikationer av PICC hos onkologiska patienter samt för att se om det finns några skillnader mellan olika diagnosgrupper och behandlingar med avseende på förekomsten av djupa ventromboser (DVT) och infektioner. Syftet är också att ta reda på hur länge en PICC sitter och hur vanligt det är att en PICC felplaceras. Meto

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Cardoso, Luciana Ventura. "Terapia da bota de unna na redução do edema em portadores de lesão venosa." Faculdade de Medicina de São José do Rio Preto, 2018. http://hdl.handle.net/tede/425.

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Submitted by Suzana Dias (suzana.dias@famerp.br) on 2018-10-22T17:35:56Z No. of bitstreams: 1 LucianaVenturaCardoso_tese.pdf: 1870589 bytes, checksum: 7ea7e78e76f10c8a1f0c87d8a6c0a5a4 (MD5)<br>Made available in DSpace on 2018-10-22T17:35:56Z (GMT). No. of bitstreams: 1 LucianaVenturaCardoso_tese.pdf: 1870589 bytes, checksum: 7ea7e78e76f10c8a1f0c87d8a6c0a5a4 (MD5) Previous issue date: 2018-04-13<br>Venous insufficiency is linked to longevity; an aggravating factor worldwidely, its main complication is venous ulcer. The boot of Unna is one of the forms of compression therapy. The bioimpedancio

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Almeida, Maria Antônia Campos. ""Fibrinogênio como marcador de trombose"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5136/tde-15092006-141829/.

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INTRODUÇÃO: Um grande número de estudos epidemiológicos têm demonstrado que o fibrinogênio é fator de risco consistente e independente para doença cardiovascular. O fibrinogênio, além de ser um determinante de trombose arterial foi considerado fator de risco de trombose venosa. Foram avaliados os níveis plasmáticos do fibrinogênio em indivíduos que apresentaram algum tipo de trombose não influenciada por reação de fase aguda ou resposta inflamatória. MÉTODOS: Neste estudo de caso-controle realizado entre julho de 2003 a abril de 2005 foram incluídos 39 pacientes, entre 25 e 65 anos, com diagnó

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Murchison, John Tallach. "New insights into the natural history of thrombo-embolic disease provided by imaging and disease quantification." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/8185.

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Venous thromboembolism (VTE) is a common disease with a myriad of presentation. It is often difficult to diagnosis with symptoms which are shared with many other disorders. Because of the overlap in symptomatology with other pathologies it is both commonly overlooked when present and commonly considered when absent. The threshold for investigating suspected VTE has dropped over time, in part due to a greater awareness of the disease among clinicians, but also because of the greater availability of diagnostic tests which are both accurate at positively diagnosing VTE and are patient friendly. T

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Hussain, Raza, Alay Mansurov, Kanishka Chakraborty, and Alisa Vasileva. "Absence of Infrarenal inferior vena cava Leading to Deep Venous Thrombosis and Incidental Finding of Nutcracker Syndrome." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/asrf/2020/presentations/17.

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Introduction: Inferior vena cava (IVC) malformations are extremely rare. Their impact with additional risk factors has not been well studied. Here, we present a case of a young female with absent IVC. She presented with an extensive left lower extremity (LLE) deep venous thrombosis (DVT) after starting oral contraceptives. Case: A 21-year-old female with no past medical history presented with progressively worsening back pain and LLE edema. Her only medication was combined oral contraceptive (OCP) which was started 4 months ago. Physical exam was significant for blue discoloration of her LLE e

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Alessio, Aline Morandi. "Avaliação das células endoteliais circulantes na trombose venosa profunda : pacientes e modelo animal." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310150.

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Orientador: Joyce Maria Anichino-Baizzacchi<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-17T00:05:28Z (GMT). No. of bitstreams: 1 Alessio_AlineMorandi_D.pdf: 8973520 bytes, checksum: 3a7a6ff893220f5bdd3d1d52da276f91 (MD5) Previous issue date: 2010<br>Resumo: As células endoteliais participam da hemostasia com efeitos pró e antitrombóticos, que podem ser estimulados por uma lesão endotelial. A presença de células endoteliais na circulação pode ser considerada um novo marcador de integridade vascular, como já desc

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Bassora, Fernanda Dutra Santiago 1982. "Avaliação da expressão gênica de marcadores inflamatórios em células mononucleares de pacientes com trombose venosa profunda." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310152.

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Orientador: Joyce Maria Annichino Bizzacchi<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T17:55:26Z (GMT). No. of bitstreams: 1 Bassora_FernandaDutraSantiago_D.pdf: 2667928 bytes, checksum: 612538a2c5c4e4e33577d2303de3a9c1 (MD5) Previous issue date: 2012<br>Resumo: A trombose venosa é definida como a oclusão de um vaso do sistema venoso. Três fatores básicos para a formação de um trombo no interior dos vasos são: alteração do fluxo sangüíneo, da parede vascular e/ou dos elementos sangüíneos. A trombose venosa

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Bayoumy, Nervana M. K. "Genetic analysis of plasma von Willebrand factor antigen levels as a risk factor for arterial and venous thrombosis." Thesis, University of Aberdeen, 2006. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU223247.

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We carried out the first genome-wide linkage analysis in British families for VWF levels. ABO and VWF loci were specifically examined. The results showed that VWF levels are highly heritable 42% ( P>0.000001) with age and C-reactive protein (CRP) the main covariates. The ABO locus was strongly associated with VWF levels ( P=2x10-18), but linkage was modest (LOD = 1.6). VWF gene marker showed no significant association or linkage with phenotype. Genome-wide linkage analysis, conditioned on age and ABO genotypes, revealed regions with potential linkage. Highlighted regions were on chromosomes 2

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Tarantino, E. "THE ROLE OF CYCLOOXYGENASE-1 (COX-1) AND CYCLOOXYGENASE-2 (COX-2) IN A VENOUS THROMBOSIS MOUSE MODEL." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/353697.

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Background: Deep vein thrombosis (DVT) is a serious national health problem, and pulmonary thromboembolism (PE) represents the life-threatening most common complication. Venous thromboembolism (VTE), including both these conditions, is traditionally treated with anticoagulant drugs. In particular, vitamin K antagonists and heparins are usually used in the reduction of thrombus development and in secondary prevention. However, the use of these drugs has several limitations: wide variability dose/response relationship between patients and in the same patient, multiple interactions with other dru

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Brock, Sheila Anne. "Compression and Doppler ultrasound of deep vein thrombosis in patients on tuberculosis treatment." Thesis, Cape Peninsula University of Technology, 2013. http://hdl.handle.net/20.500.11838/1570.

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Thesis submitted in fulfilment of the requirements for the degree of Doctor of Technology: Radiography in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology 2013<br>Background. Ultrasound has until recently been regarded as a sophisticated examination reserved for tertiary health care. In reality it is well suited to the district or primary health-care situation. A DVT (deep vein thrombosis) is an important complication of the treatment of TB and this can lead to more devastating sequelae such as a pulmonary embolus. Many DVTs are clinically silent, maki

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Farrell, Laura-Lee Amelia Catherine. "Prosthetic Vein Valve: Delivery and In Vitro Evaluation." Thesis, Available online, Georgia Institute of Technology, 2007, 2007. http://etd.gatech.edu/theses/available/etd-04042007-180135/.

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Sobieraj, Diana M., Craig I. Coleman, Vinay Pasupuleti, Abhishek Deshpande, Roop Kaw, and Adrian V. Hernández. "Comparative efficacy and safety of anticoagulants and aspirin for extended treatment of venous thromboembolism: A network meta-analysis." Elsevier B.V, 2015. http://hdl.handle.net/10757/346496.

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Diana.sobieraj@hhchealth.org<br>Objective To systematically review the literature and to quantitatively evaluate the efficacy and safety of extended pharmacologic treatment of venous thromboembolism (VTE) through network meta-analysis (NMA). Methods A systematic literature search (MEDLINE, Embase, Cochrane CENTRAL, through September 2014) and searching of reference lists of included studies and relevant reviews was conducted to identify randomized controlled trials of patients who completed initial anticoagulant treatment for VTE and then randomized for the extension study; compared extension

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Edwards, David. "Pre-Clinical Evaluation of a Novel Radiotracer for the Diagnosis of DVT and Pulmonary Embolism." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7321.

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Rosenqvist, Kerstin. "Transjugular intrahepatic portosystemic shunt in the treatment of symptomatic portal hypertension." Doctoral thesis, Uppsala universitet, Radiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-321538.

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Portal hypertension (PHT) is a condition with serious complications, such as variceal bleeding, refractory ascites and bowel ischemia. The cause of PHT may be pre-, intra- or post-hepatic. Initial treatment is pressure-reducing drugs and the treatment of acute symptoms. Ten patients presented with severe abdominal pain and acute portomesenteric venous thrombosis. Their response to systemic anticoagulation was insufficient. Treatment with primary continuous thrombolysis by a transhepatic or transjugular approach in four patients resulted in major complications, incomplete recanalization and a 7

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Swekwi, Natta. "The effects of co-prescription of warfarin and cardiovascular medicines among atrial fibrillation patients and/or deep vein thrombosis patients in Queensland, Australia." Thesis, Griffith University, 2020. http://hdl.handle.net/10072/398411.

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Introduction: Warfarin has been an anticoagulant for prophylaxis and treatment of venous thrombosis and thromboembolism in patients with atrial fibrillation for more than five decades. Due to its narrow therapeutic index, warfarin management is considerably challenging. A small change in plasma concentration can cause adverse effects which are sometimes life threatening. Thus, it is essential to monitor it closely by measuring International Normalised Ratio (INR) and Time in Therapeutic Range (TTR). Many factors such as age, weight, BMI, gender, smoking status, comorbidity, genetic factors and

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Baar, Simon [Verfasser], and Stefan-Martin [Akademischer Betreuer] Brand. "The role of HIVEP1 in endothelial platelet interaction in the context of venous thrombosis / Simon Baar ; Betreuer: Stefan-Martin Brand." Münster : Universitäts- und Landesbibliothek Münster, 2019. http://d-nb.info/1188706500/34.

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Pereira, Mora José Mauricio [Verfasser]. "Central venous catheter induced thrombosis in dogs : occurrence under an antithrombotic treatment regimen and possible indicators / José Mauricio Pereira Mora." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2020. http://d-nb.info/1225740339/34.

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Bittar, Luis Fernando 1980. "Avaliação de alterações moleculares nos genes do FVW e da ADAMTS 13 e sua correlação com os niveis plasmaticos de FVIII e FVW em pacientes com trombose venenosa profunda." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310145.

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Orientador: Joyce Annichino-Bizzacchi<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-13T01:42:43Z (GMT). No. of bitstreams: 1 Bittar_LuisFernando_M.pdf: 1309049 bytes, checksum: 8d7bbcbc4a659300d128bc58336cbb88 (MD5) Previous issue date: 2009<br>Resumo: Níveis elevados de fator VIII (FVIII) são um fator de risco independente e prevalente para trombose venosa profunda (TVP), e tem influência do FvW. A ADAMTS13 é responsável pela modulação do tamanho molecular do FvW, clivando os multímeros de altíssimo peso m

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