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1

Liu, Ling, Xiaoting Xu, Qin Sun, et al. "Neurally Adjusted Ventilatory Assist versus Pressure Support Ventilation in Difficult Weaning." Anesthesiology 132, no. 6 (2020): 1482–93. http://dx.doi.org/10.1097/aln.0000000000003207.

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Abstract Background Difficult weaning frequently develops in ventilated patients and is associated with poor outcome. In neurally adjusted ventilatory assist, the ventilator is controlled by diaphragm electrical activity, which has been shown to improve patient–ventilator interaction. The objective of this study was to compare neurally adjusted ventilatory assist and pressure support ventilation in patients difficult to wean from mechanical ventilation. Methods In this nonblinded randomized clinical trial, difficult-to-wean patients (n = 99) were randomly assigned to neurally adjusted ventilat
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2

Ongsupankul, Sorawit, Christian Capirig, and Ehab Daoud. "Bridging the gap: Enhancing synchrony in mechanical ventilation." Journal of Mechanical Ventilation 6, no. 1 (2025): 32–42. https://doi.org/10.53097/jmv.10120.

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Background Mechanical ventilation is a life-saving intervention for patients with acute respiratory failure, yet ventilator dyssynchrony—misalignment between patient effort and ventilator support—remains a common challenge in intensive care units (ICUs). Dyssynchrony is associated with prolonged ventilation, diaphragm dysfunction, increased ICU and hospital stays, and higher mortality rates. Objective This review aims to provide an in-depth analysis of the physiological control of ventilation and its interaction with mechanical ventilators, emphasizing newer technologies and strategies to enha
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3

Perez, Victor, and Jamille Pasco. "Identifying asynchronies: Early cycling." Journal of Mechanical Ventilation 4, no. 1 (2023): 57–59. http://dx.doi.org/10.53097/jmv.10073.

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Mechanical ventilation is a lifesaving treatment but can be associated with some complications such as ventilator-induced lung injury, ventilator associated pneumonia or ventilation induced diaphragm dysfunction. Although partial ventilatory support is preferred to limit some of the complications associated with controlled mechanical ventilation, there could be some problems like asynchrony between the patient and the ventilator. Asynchronies occur when the ventilator’s breath delivery does not match the patient’s ventilatory pattern or is inadequate to meet their flow demand. Asynchronies can
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4

Tobin, Martin J., Franco Laghi, and Amal Jubran. "Ventilatory Failure, Ventilator Support, and Ventilator Weaning." Comprehensive Physiology 2, no. 4 (2012): 2871–921. https://doi.org/10.1002/j.2040-4603.2012.tb00468.x.

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AbstractThe development of acute ventilatory failure represents an inability of the respiratory control system to maintain a level of respiratory motor output to cope with the metabolic demands of the body. The level of respiratory motor output is also the main determinant of the degree of respiratory distress experienced by such patients. As ventilatory failure progresses and patient distress increases, mechanical ventilation is instituted to help the respiratory muscles cope with the heightened workload. While a patient is connected to a ventilator, a physician's ability to align the rhythm
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5

Srinivasan, Shriya S., Khalil B. Ramadi, Francesco Vicario, et al. "A rapidly deployable individualized system for augmenting ventilator capacity." Science Translational Medicine 12, no. 549 (2020): eabb9401. http://dx.doi.org/10.1126/scitranslmed.abb9401.

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Strategies to split ventilators to support multiple patients requiring ventilatory support have been proposed and used in emergency cases in which shortages of ventilators cannot otherwise be remedied by production or procurement strategies. However, the current approaches to ventilator sharing lack the ability to individualize ventilation to each patient, measure pulmonary mechanics, and accommodate rebalancing of the airflow when one patient improves or deteriorates, posing safety concerns to patients. Potential cross-contamination, lack of alarms, insufficient monitoring, and inability to a
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6

Halpern, P. "(A176) Mechanical Ventilation in Disasters: “To Intubate or Not to Intubate – That is the Question!”." Prehospital and Disaster Medicine 26, S1 (2011): s49—s50. http://dx.doi.org/10.1017/s1049023x11001749.

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The provision of mechanical ventilatory support for large numbers of casualties in disasters is a complex, controversial issue. Some experts consider this modality unsuitable for large disasters and a waste of resources better devoted to eminently salvageable victims. However, the reality has usually been that rescue teams bring with them some ventilatory capability, even if only for perioperative support. Also, there are many instances when the environment, the existing and potential capacities, allow for significant numbers of victims to be saved by providing artificial ventilation, that wou
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7

Cameron, P. D., and T. E. Oh. "Newer Modes of Mechanical Ventilatory Support." Anaesthesia and Intensive Care 14, no. 3 (1986): 258–66. http://dx.doi.org/10.1177/0310057x8601400306.

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Recent modes of ventilatory support aim to facilitate weaning and minimise the physiological disadvantages of intermittent positive pressure ventilation (IPPV). Intermittent mandatory ventilation (IMV) allows the patient to breathe spontaneously in between ventilator breaths. Mandatory minute volume ventilation (MMV) ensures that the patient always receives a preset minute volume, made up of both spontaneous and ventilator breaths. Pressure supported (assisted) respiration is augmentation of a spontaneous breath up to a preset pressure level, and is different from ‘triggering’, which is a pati
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8

VanKoevering, Kyle K., Pratyusha Yalamanchi, Catherine T. Haring, et al. "Delivery system can vary ventilatory parameters across multiple patients from a single source of mechanical ventilation." PLOS ONE 15, no. 12 (2020): e0243601. http://dx.doi.org/10.1371/journal.pone.0243601.

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Background Current limitations in the supply of ventilators during the Covid19 pandemic have limited respiratory support for patients with respiratory failure. Split ventilation allows a single ventilator to be used for more than one patient but is not practicable due to requirements for matched patient settings, risks of cross-contamination, harmful interference between patients and the inability to individualize ventilator support parameters. We hypothesized that a system could be developed to circumvent these limitations. Methods and findings A novel delivery system was developed to allow i
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9

Lacerda, Rodrigo Silva, Fernando Cesar Anastácio de Lima, Leonardo Pereira Bastos, et al. "Benefits of Manometer in Non-Invasive Ventilatory Support." Prehospital and Disaster Medicine 32, no. 6 (2017): 615–20. http://dx.doi.org/10.1017/s1049023x17006719.

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AbstractIntroductionEffective ventilation during cardiopulmonary resuscitation (CPR) is essential to reduce morbidity and mortality rates in cardiac arrest. Hyperventilation during CPR reduces the efficiency of compressions and coronary perfusion.ProblemHow could ventilation in CPR be optimized? The objective of this study was to evaluate non-invasive ventilator support using different devices.MethodsThe study compares the regularity and intensity of non-invasive ventilation during simulated, conventional CPR and ventilatory support using three distinct ventilation devices: a standard manual r
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10

Jaber, Samir, Mustapha Sebbane, Daniel Verzilli, et al. "Adaptive Support and Pressure Support Ventilation Behavior in Response to Increased Ventilatory Demand." Anesthesiology 110, no. 3 (2009): 620–27. http://dx.doi.org/10.1097/aln.0b013e31819793fb.

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Background Dual-control modes of ventilation adapt the pressure delivery to keep a volume target in response to changes in respiratory mechanics, but they may respond poorly to changes in ventilatory demand. Adaptive support ventilation (ASV), a complex minute volume-targeted pressure-regulated ventilation, was compared to adaptive pressure ventilation (APV), a dual-mode in which the pressure level is adjusted to deliver a preset tidal volume, and to pressure support ventilation (PSV) when facing an increase in ventilatory demand. Methods A total of 14 intensive care unit patients being weaned
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11

Perez, Victor, and Jamille Pasco. "Identifying asynchronies: Early cycling." Journal of Mechanical Ventilation 4, no. 1 (2023): 57–59. https://doi.org/10.53097/JMV.10073.

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<strong>Abstract</strong> Mechanical ventilation is a lifesaving treatment but can be associated with some complications such as ventilator-induced lung injury, ventilator associated pneumonia or ventilation induced diaphragm dysfunction. Although partial ventilatory support is preferred to limit some of the complications associated with controlled mechanical ventilation, there could be some problems like asynchrony between the patient and the ventilator. Asynchronies occur when the ventilator&rsquo;s breath delivery does not match the patient&rsquo;s ventilatory pattern or is inadequate to me
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12

Still, Joseph, Terry Newton, Bruce Friedman, Steve Furhman, Edward Law, and John Dawson. "Experience with Pneumonia in Acutely Burned Patients Requiring Ventilator Support." American Surgeon 66, no. 2 (2000): 206–9. http://dx.doi.org/10.1177/000313480006600220.

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Acutely burned patients requiring ventilatory support who developed pneumonia while in the hospital were retrospectively reviewed. The Centers for Disease Control and Prevention (CDC) clinical criteria for pneumonia are based on clinical findings, radiographic findings, and culture data. During an 18-month period, 784 burn patients were admitted. Of these, 145 (18.5%) were placed on ventilators for at least 1 day. Fifty-three (36.6%) patients on ventilators developed acute pneumonia based on CDC criteria. Identification of causative organisms was based on positive cultures from blood or endotr
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13

Grossbach, Irene, Linda Chlan, and Mary Fran Tracy. "Overview of Mechanical Ventilatory Support and Management of Patient- and Ventilator-Related Responses." Critical Care Nurse 31, no. 3 (2011): 30–44. http://dx.doi.org/10.4037/ccn2011595.

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Nurses must be knowledgeable about the function and limitations of ventilator modes, causes of respiratory distress and dyssynchrony with the ventilator, and appropriate management in order to provide high-quality patient-centered care. Prompt recognition of problems and action by the nurse may resolve acute respiratory distress, dyspnea, and increased work of breathing and prevent adverse events. This article presents an overview of mechanical ventilation modes and the assessment and management of dyspnea and patient-ventilator dyssynchrony. Strategies to manage patients’ responses to mechani
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14

Bersten, A. D., A. J. Rutten, and A. E. Vedig. "Efficacy of Pressure Support in Compensating for Apparatus Work." Anaesthesia and Intensive Care 21, no. 1 (1993): 67–71. http://dx.doi.org/10.1177/0310057x9302100116.

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Breathing through an endotracheal tube, connector, and ventilator demand valve imposes an added load on the respiratory muscles. As respiratory muscle fatigue is thought to be a frequent cause of ventilator dependence, we sought to examine the efficacy of five different ventilators in reducing this imposed work through the application of pressure support ventilation. Using a model of spontaneous breathing, we examined the apparatus work imposed by the Servo 900-C, Puritan Bennett 7200a, Engstrom Erica, Drager EV-A or Hamilton Veolar ventilators, a size 7.0 and 8.0 mm endotracheal tube, and ins
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15

Mokra, D., P. Mikolka, P. Kosutova, et al. "Effects of Conventional Mechanical Ventilation Performed by Two Neonatal Ventilators on the Lung Functions of Rabbits with Meconium-Induced Acute Lung Injury." Acta Medica Martiniana 16, no. 3 (2016): 5–13. http://dx.doi.org/10.1515/acm-2016-0012.

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AbstractSevere meconium aspiration syndrome (MAS) in the neonates often requires a ventilatory support. As a method of choice, a conventional mechanical ventilation with small tidal volumes (VT&lt;6 ml/kg) and appropriate ventilatory pressures is used. The purpose of this study was to assess the short-term effects of the small-volume CMV performed by two neonatal ventilators: Aura V (Chirana Stara Tura a.s., Slovakia) and SLE5000 (SLE Ltd., UK) on the lung functions of rabbits with experimentally-induced MAS and to estimate whether the newly developed neonatal version of the ventilator Aura V
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16

Restrick, LJ, NC Fox, G. Braid, EM Ward, EA Paul, and JA Wedzicha. "Comparison of nasal pressure support ventilation with nasal intermittent positive pressure ventilation in patients with nocturnal hypoventilation." European Respiratory Journal 6, no. 3 (1993): 364–70. http://dx.doi.org/10.1183/09031936.93.06030364.

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Nasal intermittent positive pressure ventilation (NIPPV) provides effective ventilatory support in patients with nocturnal hypoventilation. Nasal pressure support ventilation (NPSV), which only provides ventilation in response to patient triggering, may also be effective, simpler, and cheaper, but has not been evaluated. NIPPV and NPSV were compared in 12 patients with nocturnal hypoventilation, requiring domiciliary ventilatory support. The patients were studied on three consecutive nights, in random order: a control night without ventilation and a night on each mode of ventilatory support us
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17

Doorduin, Jonne, Christer A. Sinderby, Jennifer Beck, Johannes G. van der Hoeven, and Leo M. A. Heunks. "Assisted Ventilation in Patients with Acute Respiratory Distress Syndrome." Anesthesiology 123, no. 1 (2015): 181–90. http://dx.doi.org/10.1097/aln.0000000000000694.

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Abstract Background: In patients with acute respiratory distress syndrome (ARDS), the use of assisted mechanical ventilation is a subject of debate. Assisted ventilation has benefits over controlled ventilation, such as preserved diaphragm function and improved oxygenation. Therefore, higher level of “patient control” of ventilator assist may be preferable in ARDS. However, assisted modes may also increase the risk of high tidal volumes and lung-distending pressures. The current study aims to quantify how differences in freedom to control the ventilator affect lung-protective ventilation, brea
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18

Raymond, Samuel J., Sam Baker, Yuzhe Liu, et al. "A low-cost, highly functional, emergency use ventilator for the COVID-19 crisis." PLOS ONE 17, no. 3 (2022): e0266173. http://dx.doi.org/10.1371/journal.pone.0266173.

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Respiratory failure complicates most critically ill patients with COVID-19 and is characterized by heterogeneous pulmonary parenchymal involvement, profound hypoxemia and pulmonary vascular injury. The high incidence of COVID-19 related respiratory failure has exposed critical shortages in the supply of mechanical ventilators, and providers with the necessary skills to treat. Traditional mass-produced ventilators rely on an internal compressor and mixer to moderate and control the gas mixture delivered to a patient. However, the current emergency has energized the pursuit of alternative design
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19

Bhoyar, Ankit D. "Design Construction and Performance Test of a Low-Cost Pandemic Ventilator for Breathing Support." International Journal for Research in Applied Science and Engineering Technology 9, no. 8 (2021): 2374–80. http://dx.doi.org/10.22214/ijraset.2021.37771.

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Abstract: Mass casualty incidents such as those that are being experienced during the novel coronavirus disease (COVID-19) pandemic can overwhelm local healthcare systems, where the number of casualties exceeds local resources and capabilities in a short period of time. The introduction of patients with worsening lung function as a result of COVID-19 has strained traditional ventilator supplies. Mechanical ventilator is a medical device which is usually utilized to ventilate patients who cannot breathe adequately on their own. Among many types of ventilators Bag Valve Mask (BVM) is a manual ve
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20

Jung, Boris, Jean-Michel Constantin, Nans Rossel, et al. "Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet." Anesthesiology 112, no. 6 (2010): 1435–43. http://dx.doi.org/10.1097/aln.0b013e3181d7b036.

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Background Contrary to adaptive support ventilation (ASV), prolonged totally controlled mechanical ventilation (CMV) results in the absence of diaphragm activity and causes ventilator-induced diaphragmatic dysfunction. Because maintaining respiratory muscles at rest is likely a major cause of ventilator-induced diaphragmatic dysfunction, ASV may prevent its occurrence in comparison with CMV. The aim of our study was to compare the effects of ASV with those of CMV on both in vivo and in vitro diaphragmatic properties. Methods Two groups of six anesthetized piglets were ventilated during a 72-h
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21

Panagiotou, Panagiota, Christina Kanaka-Gantenbein, and Athanasios G. Kaditis. "Changes in Ventilatory Support Requirements of Spinal Muscular Atrophy (SMA) Patients Post Gene-Based Therapies." Children 9, no. 8 (2022): 1207. http://dx.doi.org/10.3390/children9081207.

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Spinal muscular atrophy (SMA) is a genetic neuromuscular disease resulting in global muscular weakness and, frequently, in respiratory failure and premature death. Gene-based therapies like Nusinersen are now available for patients with SMA. The aim of this review was to assess in “real world” studies, whether novel treatments would have a positive impact on the mechanical ventilatory support requirements of SMA patients, already initiated on ventilatory support prior to treatment administration. A literature search was performed in Pubmed using multiple combinations of MESH terms and the snow
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22

Salah, B. Alanazi, M. Alanazi Abdulkhaliq, A. Alqahtani Mansour, M. Al-Anazi Nawaf, and A. Alanazi Nailah. "The Role of Respiratory Therapists in Enhancing Capnography Accuracy for Critically Ill Patients: A Retrospective Analysis in a Tertiary Care ICU." International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences 12, no. 4 (2024): 1–8. https://doi.org/10.5281/zenodo.14013255.

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Background: Capnography is a critical monitoring tool in the management of mechanically ventilated patients in the ICU. Ensuring its accuracy is essential for proper ventilatory support and improved patient outcomes. Respiratory therapists (RTs) play a key role in maintaining capnography accuracy and managing ventilator settings. Objective: This study aimed to evaluate the impact of RT-led interventions on the accuracy of capnography monitoring and patient outcomes in critically ill patients in a tertiary hospital ICU. Methods: &nbsp;A retrospective cohort study of 150 mechanically ventilated
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Salah, B. Alanazi, M. Alanazi Abdulkhaliq, A. Alqahtani Mansour, M. Al-Anazi Nawaf, and A. Alanazi Nailah. "The Role of Respiratory Therapists in Enhancing Capnography Accuracy for Critically Ill Patients: A Retrospective Analysis in a Tertiary Care ICU." International Journal on Science and Technology 15, no. 3 (2024): 1–9. https://doi.org/10.5281/zenodo.14801497.

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Background:Capnography is a critical monitoring tool in the management of mechanically ventilated patients in the ICU. Ensuring its accuracy is essential for proper ventilatory support and improved patient outcomes. Respiratory therapists (RTs) play a key role in maintaining capnography accuracy and managing ventilator settings.&nbsp; &nbsp;&nbsp;Objective: This study aimed to evaluate the impact of RT-led interventions on the accuracy of capnography monitoring and patient outcomes in critically ill patients in a tertiary hospital ICU. Methods: &nbsp;A retrospective cohort study of 150 mechani
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24

Buiteman-Kruizinga, Laura A., Ary Serpa Neto, Michela Botta, et al. "Effect of automated versus conventional ventilation on mechanical power of ventilation—A randomized crossover clinical trial." PLOS ONE 19, no. 7 (2024): e0307155. http://dx.doi.org/10.1371/journal.pone.0307155.

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Introduction Mechanical power of ventilation, a summary parameter reflecting the energy transferred from the ventilator to the respiratory system, has associations with outcomes. INTELLiVENT–Adaptive Support Ventilation is an automated ventilation mode that changes ventilator settings according to algorithms that target a low work–and force of breathing. The study aims to compare mechanical power between automated ventilation by means of INTELLiVENT–Adaptive Support Ventilation and conventional ventilation in critically ill patients. Materials and methods International, multicenter, randomized
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25

Dargaville, Peter A. "Respiratory Support in Meconium Aspiration Syndrome: A Practical Guide." International Journal of Pediatrics 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/965159.

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Meconium aspiration syndrome (MAS) is a complex respiratory disease of the term and near-term neonate. Inhalation of meconium causes airway obstruction, atelectasis, epithelial injury, surfactant inhibition, and pulmonary hypertension, the chief clinical manifestations of which are hypoxaemia and poor lung compliance. Supplemental oxygen is the mainstay of therapy for MAS, with around one-third of infants requiring intubation and mechanical ventilation. For those ventilated, high ventilator pressures, as well as a relatively long inspiratory time and slow ventilator rate, may be necessary to a
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26

Rajbanshi, L. K., M. Dali, S. B. Karki, K. Khanal, B. Aryal, and K. Chapagain. "Adaptive Support Ventilation as a Sole Mode of Mechanical Ventilation-An Observational Study." Birat Journal of Health Sciences 1, no. 1 (2017): 8–12. http://dx.doi.org/10.3126/bjhs.v1i1.17090.

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Introduction Adaptive support ventilation (ASV) is a close loop dual control mechanical ventilation mode. This mode can automatically change its parameters to weaning mode once the patient is actively breathing converting volume targeted pressure control mode to volume targeted pressure support mode. We aimed to observe the outcome of the patients ventilated with ASV as a sole mode in terms of duration of mechanical ventilation, duration of weaning from the ventilatory support and length of Intensive care unit (ICU) stay.Methodology We conducted a prospective observational study for the durati
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Mireles-Cabodevila, Eduardo, Enrique Diaz-Guzman, Alejandro C. Arroliga, and Robert L. Chatburn. "Human versus Computer Controlled Selection of Ventilator Settings: An Evaluation of Adaptive Support Ventilation and Mid-Frequency Ventilation." Critical Care Research and Practice 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/204314.

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Background. There are modes of mechanical ventilation that can select ventilator settings with computer controlled algorithms (targeting schemes). Two examples are adaptive support ventilation (ASV) and mid-frequency ventilation (MFV). We studied how different clinician-chosen ventilator settings are from these computer algorithms under different scenarios.Methods. A survey of critical care clinicians provided reference ventilator settings for a 70 kg paralyzed patient in five clinical/physiological scenarios. The survey-derived values for minute ventilation and minute alveolar ventilation wer
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28

Piesesha, Virgiana. "Ventilator Weaning Difficulties in ICU: A Study on VAP Patients with Post-Tracheostomy, Thoracic Trauma, and Thoracic Spinal Cord Injury." Jurnal Kegawatdaruratan Medis Indonesia 4, no. 1 (2025): 1–13. https://doi.org/10.58545/jkmi.v4i1.154.

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Ventilator weaning failure is an inability to adapt to reduced mechanical ventilator assistance, which can slow down and prolong the weaning process. Ventilator weaning failure is characterized by increased respiratory rate, use of respiratory muscles, gasping breath, out-of-synchronization efforts to assist breathing and ventilator support, shallow breathing, agitation, and abnormal blood gas arteries. Ventilator weaning failure is an inability to spontaneous breathing trial (SBT), re-intubation, and assisted ventilation after extubation or death within 48 hours after extubation. Weaning proc
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Alfaray, Ricky Indra, Muhammad Iqbal Mahfud, and Rafiqy Sa'adiy Faizun. "Duration Of Ventilation Support Usage And Development Of Ventilator-Associated Pneumonia: When Is The Most Time At Risk?" Indonesian Journal of Anesthesiology and Reanimation 1, no. 1 (2019): 26. http://dx.doi.org/10.20473/ijar.v1i12019.26-31.

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Introduction: Ventilator-Associated pneumonia (VAP) is pneumonia that occurs in patients who have been mechanically ventilated for a duration of more than 48 hours. The duration of ventilator use was identified as a risk factor which is a trigger of VAP. Objective: This study aimed to determine the association between the duration of ventilator use and the incidence of VAP in patients in the Intensive Care Unit of Dr. Mohammad Hoesin General Hospital, Palembang. Method and Material: This study was an observational analytic study using a cross-sectional design. The samples were all patients who
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Su, Marissa, and ehab daoud. "Effect of respiratory effort on target minute ventilation during Adaptive Support Ventilation." Journal of Mechanical Ventilation 2, no. 2 (2021): 53–58. http://dx.doi.org/10.53097/jmv.10022.

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Background: Adaptive support ventilation (ASV) is an intelligent mode of mechanical ventilation protocol which uses a closed-loop control between breaths. The algorithm states that for a given level of alveolar ventilation, there is a particular respiratory rate and tidal volume which achieve a lower work of breathing. The mode allows the clinician to set a desired minute ventilation percentage (MV%) while the ventilator automatically selects the target ventilatory pattern base on these inputs and feedback from the ventilator monitoring system. The goal is to minimize the work of breathing and
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Gonzales Carazas, Maryanne Melanie, Cesar Miguel Gavidia, Roberto Davila Fernandez, et al. "Biological evaluation of a mechanical ventilator that operates by controlling an automated manual resuscitator. A descriptive study in swine." PLOS ONE 17, no. 3 (2022): e0264774. http://dx.doi.org/10.1371/journal.pone.0264774.

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The Covid-19 outbreak challenged health systems around the world to design and implement cost-effective devices produced locally to meet the increased demand of mechanical ventilators worldwide. This study evaluates the physiological responses of healthy swine maintained under volume- or pressure-controlled mechanical ventilation by a mechanical ventilator implemented to bring life-support by automating a resuscitation bag and closely controlling ventilatory parameters. Physiological parameters were monitored in eight sedated animals (t0) prior to inducing deep anaesthesia, and during the next
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32

Pamugar, Bramantyo, and Dhany Budipratama. "Lung Protective Strategy in Acute Respiratory Distress Syndrome with Approach of Compliance and Mechanical Power." Journal of Society Medicine 2, no. 10 (2023): 324–29. https://doi.org/10.47353/jsocmed.v2i10.96.

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Introduction: Lung protective strategy was meant to decrese risk of ventilatory induced lung injury without reducing benefit of ventilator. One of the approaches were the use of compliance and mechanical power (MP). Compliance was used to determine how large lung was recruited after ventilatory support. Mechanical power was used to determined enough ventilatory support to that patient. Case Report: We reported 36 years old female, whom admitted to ICU with diagnosis of acute respiratory distress syndrome caused by community acquired pneumonia. Patient was given pressure controlled ventilation
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Spahija, Jadranka, Michel de Marchie, Martin Albert, et al. "Patient-ventilator interaction during pressure support ventilation and neurally adjusted ventilatory assist*." Critical Care Medicine 38, no. 2 (2010): 518–26. http://dx.doi.org/10.1097/ccm.0b013e3181cb0d7b.

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34

Clochesy, JM, BJ Daly, and HD Montenegro. "Weaning chronically critically ill adults from mechanical ventilatory support: a descriptive study." American Journal of Critical Care 4, no. 2 (1995): 93–99. http://dx.doi.org/10.4037/ajcc1995.4.2.93.

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BACKGROUND: Ventilator-dependent patients average 11,419 daily in US acute care hospitals. OBJECTIVE: To describe the process of ventilatory weaning among chronically critically ill adults. METHODS A retrospective survey was used to study ventilator-dependent adults enrolled in a larger randomized study. Patients records were used to obtain duration of mechanical ventilatory support, success of weaning, serum albumin level, left ventricular function, number of drugs used to treat heart failure, and 24-hour fluid balance. Data were collected on admission to the intensive care unit; 24 hours aft
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35

Vadodariya, Namrata, and Harsha Jivarajani. "Association of Ventilator Associated Pneumonia with Various Risk Factors in Patients at Ahmedabad, Gujarat." Indian Journal of Emergency Medicine 4, no. 2 (2018): 93–98. http://dx.doi.org/10.21088/ijem.2395.311x.4218.4.

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Background and Aim: Ventilator associated pneumonia (VAP) is a common complication in critically ill patient affecting 9 to 27% of all critically ill patients. We have done the study of ventilator associated pneumonia (VAP) with various risk factors like age, sex, duration of ventilation, airway access, various organisms and their culture and sensitivity to various antibiotics and comorbid conditions associated with ventilator associated pneumonia. Material and Methods: The present study was conducted in our Medical ICU of Civil Hospital during period from November 2009 to November 2011. It in
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Jaber, Samir, Didier Tassaux, Mustapha Sebbane, et al. "Performance Characteristics of Five New Anesthesia Ventilators and Four Intensive Care Ventilators in Pressure-support Mode." Anesthesiology 105, no. 5 (2006): 944–52. http://dx.doi.org/10.1097/00000542-200611000-00015.

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Background During the past few years, many manufacturers have introduced new modes of ventilation in anesthesia ventilators, especially partial-pressure modalities. The current bench test study was designed to compare triggering and pressurization of five new anesthesia ventilators with four intensive care unit ventilators. Methods Ventilators were connected to a two-compartment lung model. One compartment was driven by an intensive care unit ventilator to mimic "patient" inspiratory effort, whereas the other was connected to the tested ventilator. The settings of ventilators were positive end
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Eweas, Amany S., Sahar Y. Mohammad, Jehan S. A. Sayyed, Marwa M. Abd Elbaky, and Magda M. Bayoumi. "Application of Modified Ventilator Bundle and Its Effect on Weaning and Ventilation Days among Critical Ill Patients." Evidence-Based Nursing Research 2, no. 4 (2021): 9. http://dx.doi.org/10.47104/ebnrojs3.v2i4.178.

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Context: Modified ventilator bundle is the group of interventions supported by evidence to prevent ventilator-associated pneumonia and other related complications that commonly occurred in mechanically ventilated patients. Furthermore, it helps in reducing the mortality rates and hospital length of stay.&#x0D; Aim: The current study aimed to apply a modified ventilator bundle and evaluate its effect on weaning and ventilation days among critically ill patients.&#x0D; Methods: A quasi-experimental research (study/control group) design was utilized. This study was conducted at the following crit
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Koryakin, A. G., A. V. Vlasenko, E. P. Rodionov, and E. A. Evdokimov. "Asynchronies during respiratory support." Medical alphabet, no. 17 (September 8, 2022): 50–61. http://dx.doi.org/10.33667/2078-5631-2022-17-50-61.

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Asynchronies (desynchronies, dyssynchrony) is a disturbance of the harmonious interaction between the patient’s respiratory system and а ventilator. Asynchronies occur as a result of various reasons and with any form of respiratory support (non-invasive, assisted or fully controlled mechanical ventilation). Asynchrony is a significant cause of biomechanics and gas exchange disorders in the development of both self-injury and ventilator-induced lung injury, an increase of the respiratory support duration and mortality in patients with respiratory failure. Understanding the mechanisms of the asy
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39

Gallagher, John J. "Alternative Modes of Mechanical Ventilation." AACN Advanced Critical Care 29, no. 4 (2018): 396–404. http://dx.doi.org/10.4037/aacnacc2018372.

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Modern mechanical ventilators are more complex than those first developed in the 1950s. Newer ventilation modes can be difficult to understand and implement clinically, although they provide more treatment options than traditional modes. These newer modes, which can be considered alternative or nontraditional, generally are classified as either volume controlled or pressure controlled. Dual-control modes incorporate qualities of pressure-controlled and volume-controlled modes. Some ventilation modes provide variable ventilatory support depending on patient effort and may be classified as close
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Nuschke, John, and Brooke Judd. "1236 A Challenging Transition Between Volume Assured Modes in a Patient with Congenital Lung Abnormalities." SLEEP 47, Supplement_1 (2024): A526. http://dx.doi.org/10.1093/sleep/zsae067.01236.

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Abstract Introduction The advent of volume-assured modes for non-invasive ventilation (NIV) has improved treatment of more complicated sleep-disordered breathing (SDB), although can present challenges in choosing ventilatory modes in patients with abnormal pulmonary anatomy. Report of case(s) Our Patient is a 44 year-old female with hypoplastic right lung, pulmonary hypertension and chronic hypercapnic/hypoxic respiratory failure on nocturnal NIV for complex sleep disordered breathing. She failed CPAP, BIPAP and BIPAP S/T. Average volume assured pressure support (AVAPS) NIV was initiated with
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41

Bhoyar, Ankit D. "Evolution and Characteristics of Bag-Valve-Mask Ventilation During Pandemic: A Review of the Literature." International Journal for Research in Applied Science and Engineering Technology 9, no. VII (2021): 25–29. http://dx.doi.org/10.22214/ijraset.2021.36227.

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Mass casualty incidents such as those that are being experienced during the novel coronavirus disease (COVID-19) pandemic can overwhelm local healthcare systems, where the number of casualties exceeds local resources and capabilities in a short period of time. The introduction of patients with worsening lung function as a result of COVID-19 has strained traditional ventilator supplies. To bridge the gap during ventilator shortages and to help clinicians triage patients, manual resuscitator devices can be used to deliver respirations to a patient requiring breathing support. For patients who re
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Rolland-Debord, Camille, Côme Bureau, Tymothee Poitou, et al. "Prevalence and Prognosis Impact of Patient–Ventilator Asynchrony in Early Phase of Weaning according to Two Detection Methods." Anesthesiology 127, no. 6 (2017): 989–97. http://dx.doi.org/10.1097/aln.0000000000001886.

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Abstract Background Patient–ventilator asynchrony is associated with a poorer outcome. The prevalence and severity of asynchrony during the early phase of weaning has never been specifically described. The authors’ first aim was to evaluate the prognosis impact and the factors associated with asynchrony. Their second aim was to compare the prevalence of asynchrony according to two methods of detection: a visual inspection of signals and a computerized method integrating electromyographic activity of the diaphragm. Methods This was an ancillary study of a multicenter, randomized controlled tria
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Breen, D. P., A. D. Spiers, and J. W. Stokes. "A Continuous High Flow Intermittent Mandatory Ventilation System Incorporating a Downs Venturi Device and a Modified Nuffield Series 200 Ventilator." Anaesthesia and Intensive Care 16, no. 3 (1988): 351–57. http://dx.doi.org/10.1177/0310057x8801600318.

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Systems for respiratory support are becoming increasingly expensive and complex. Many systems suffer inadequacies when used for spontaneous ventilation. Some modes on newer ventilators are rarely used because of the complex controls and settings. There is no truly universal ventilator that satisfies every intensivist's wishes. CPAP/IMV is becoming accepted as the standard management of many patients with acute respiratory failure and there would be few intensive care units where CPAP/IMV is not used for part of a patient's respiratory support. We describe a cost-effective system that may be us
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Holanda, Marcelo Alcantara, Renata dos Santos Vasconcelos, Juliana Carvalho Ferreira, and Bruno Valle Pinheiro. "Patient-ventilator asynchrony." Jornal Brasileiro de Pneumologia 44, no. 4 (2018): 321–33. http://dx.doi.org/10.1590/s1806-37562017000000185.

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ABSTRACT Patient-v entilator asynchrony (PVA) is a mismatch between the patient, regarding time, flow, volume, or pressure demands of the patient respiratory system, and the ventilator, which supplies such demands, during mechanical ventilation (MV). It is a common phenomenon, with incidence rates ranging from 10% to 85%. PVA might be due to factors related to the patient, to the ventilator, or both. The most common PVA types are those related to triggering, such as ineffective effort, auto-triggering, and double triggering; those related to premature or delayed cycling; and those related to i
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Imanaka, Hideaki, Dean Hess, Max Kirmse, et al. "Inaccuracies of Nitric Oxide Delivery Systems during Adult Mechanical Ventilation." Anesthesiology 86, no. 3 (1997): 676–88. http://dx.doi.org/10.1097/00000542-199703000-00021.

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Background Various systems to administer inhaled nitric oxide (NO) have been used in patients and experimental animals. We used a lung model to evaluate five NO delivery systems during mechanical ventilation with various ventilatory patterns. Methods An adult mechanical ventilator was attached to a test lung configured to separate inspired and expired gases. Four injection systems were evaluated with NO injected either into the inspiratory circuit 90 cm proximal to the Y piece or directly at the Y piece and delivered either continuously or only during the inspiratory phase. Alternatively, NO w
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Ankireddy, Korisipati, and Aruna Jyothi K. "A study on symptoms of children mechanically ventilated in a paediatric intensive care unit of a minimum resource setting in tertiary care centre." International Journal of Contemporary Pediatrics 6, no. 2 (2019): 574. http://dx.doi.org/10.18203/2349-3291.ijcp20190689.

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Background: Mechanical ventilation, a lifesaving intervention in a critical care unit is under continuous evolution in modern era. Despite this, the management of children with invasive ventilation in developing countries with limited resources is challenging. The study analyses the clinical profile, indications, complications and duration of ventilator care in limited resource settings. Methods: A retrospective study of critically ill children mechanically ventilated in an intensive care unit of a tertiary care government hospital. Results: A total of 120 children required invasive ventilatio
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Pierce, JD, and K. Gerald. "Differences in end-tidal carbon dioxide and breathing patterns in ventilator-dependent patients using pressure support ventilation." American Journal of Critical Care 3, no. 4 (1994): 276–81. http://dx.doi.org/10.4037/ajcc1994.3.4.276.

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BACKGROUND: Although several investigators have assessed the effects of pressure support ventilation on tidal volume and breathing patterns, none have investigated the combination of breathing patterns and end-tidal carbon dioxide in ventilator-dependent patients. OBJECTIVES: To determine the differences in end-tidal carbon dioxide and breathing patterns at varying pressure support ventilation levels in ventilator-dependent patients. METHODS: Breathing patterns were measured with a plethysmograph and a ventilator. End-tidal carbon dioxide was measured by connecting the capnography sampler to t
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Mathur, S. K., S. Kun, T. G. Keens, and I. A. Perez. "0874 Patients with Congenital Central Hypoventilation Syndrome Do Not Wake Up to Ventilator Alarms." Sleep 43, Supplement_1 (2020): A333. http://dx.doi.org/10.1093/sleep/zsaa056.870.

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Abstract Introduction Congenital Central Hypoventilation Syndrome (CCHS) requires lifelong ventilatory support during sleep. CCHS patients are vulnerable to sleep disturbances associated with treatments, monitoring alarms, and care they receive. We hypothesized that sleep would be disrupted in CCHS patient’s due to ventilatory support and other treatments at night. Methods An anonymous survey of CCHS patients aged 0-17 years was conducted through REDCAP. Patients were recruited in person, by flyer, email, and social media. Data collected included demographics, PHOX2B genotype, ventilatory supp
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Constantin, J. M., E. Futier, L. Combaret, D. Attaix, and J. E. Bazin. "Pressure support ventilation reduce ventilator-induced diaphragmatic dysfunction." European Journal of Anaesthesiology 23, Supplement 37 (2006): 76. http://dx.doi.org/10.1097/00003643-200606001-00272.

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Romano, Thiago Gomes, Pedro Vitale Mendes, Marcelo Park, and Eduardo Leite Vieira Costa. "Extracorporeal respiratory support in adult patients." Jornal Brasileiro de Pneumologia 43, no. 1 (2017): 60–70. http://dx.doi.org/10.1590/s1806-37562016000000299.

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ABSTRACT In patients with severe respiratory failure, either hypoxemic or hypercapnic, life support with mechanical ventilation alone can be insufficient to meet their needs, especially if one tries to avoid ventilator settings that can cause injury to the lungs. In those patients, extracorporeal membrane oxygenation (ECMO), which is also very effective in removing carbon dioxide from the blood, can provide life support, allowing the application of protective lung ventilation. In this review article, we aim to explore some of the most relevant aspects of using ECMO for respiratory support. We
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