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Journal articles on the topic 'Vernonia amydalina'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Chidera V. Eboh, Chukwubuikem C. Okolo, Ogechi O. Anyanwu, Nkeoma N. Okoye, Chigozie C. Ezeagha, and Festus B.C. Okoye. "Metabolites of Colletrotricum species, an endophytic fungus isolated from Vernonia amygdalina Del possess antimicrobial and antioxidant activities." GSC Biological and Pharmaceutical Sciences 20, no. 3 (2022): 148–59. http://dx.doi.org/10.30574/gscbps.2022.20.3.0323.

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The endophytic fungus, colletrotricum species, isolated from the leaves of Vernonia amygdalina was investigated for its chemical constituents and biological activity. The pure fungus was grown using solid fermentation on rice medium and the metabolites were extracted using ethyl acetate. Further purification of the extract was carried out using vacuum liquid chromatography (VLC) and gel chromatography on Sephadex LH-20. The chemical constituents were detected by dereplication using HPLC-DAD. Antimicrobial assay of the Sephadex fractions EC3-1 and EC3-3 were evaluated using agar well diffusion

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2

Chidera, V. Eboh, C. Okolo Chukwubuikem, O. Anyanwu Ogechi, N. Okoye Nkeoma, C. Ezeagha Chigozie, and B.C. Okoye Festus. "Metabolites of Colletrotricum species, an endophytic fungus isolated from Vernonia amygdalina Del possess antimicrobial and antioxidant activities." GSC Biological and Pharmaceutical Sciences 20, no. 3 (2022): 148–59. https://doi.org/10.5281/zenodo.7142366.

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The endophytic fungus, <em>colletrotricum</em> species, isolated from the leaves of <em>Vernonia amygdalina </em>was investigated for its chemical constituents and biological activity. The pure fungus was grown using solid fermentation on rice medium and the metabolites were extracted using ethyl acetate. Further purification of the extract was carried out using vacuum liquid chromatography (VLC) and gel chromatography on Sephadex LH-20. The chemical constituents were detected by dereplication using HPLC-DAD. Antimicrobial assay of the Sephadex fractions EC3-1 and EC3-3 wer

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3

Wirasti, Wirasti, Farahdina Ulfah, and Slamet Slamet. "Karakterisasi Sediaan Suspensi Nanopratikel Ekstrak Etanol Daun Afrika (Vernonia Amygdalina Del.)." Cendekia Journal of Pharmacy 4, no. 2 (2020): 138–48. http://dx.doi.org/10.31596/cjp.v4i2.107.

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Nanopartikel merupakan partikel koloid atau padatan dengan diameter berukuran 10 – 1000 nm. Daun Afrika (Vernonia amydalina Del.) merupakan tanaman yang memiliki banyak manfaat dalam pengobatan, Penelitian ini bertujuan untukformulasinanopartikel ekstrak etanol Daun Afrika sebagai zat aktif dalam sediaan suspensi dan mengevaluasinya. Metode pembuatan nanopartikel ekstrak etanol Daun Afrika pada penelitian ini yaitu metode gelasi ionik. Nanopartikel ekstrak etanol Daun Afrika dikarakterisasi menggunakan PSA. Evaluasi sediaan suspensi meliputi uji organoleptik, pH, viskositas, sedimentasi, volum

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4

Frank Uchenna, Eneh, Okeke Chidi Benjamin, Igbokwe Gabriel Ejike, Okpala Chukwuemeka Obumneme, and Nwachukwu Godslove Pephel. "Antibacterial Effects of Aqueous Ethanolic Leaf Extracts of Ocimum gratissimum, Cymbopogon citratus, Vernonia amygdalina and Annona muricata on the Isolated Pathogenic Organism of Citrus Canker from Citrus sinensis (Sweet Orange)." Journal of Biotechnology Research, no. 58 (August 25, 2019): 64–68. http://dx.doi.org/10.32861/jbr.58.64.68.

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The aqueous ethanolic extracts of Vernonia amygdalina, Ocimum gratissimum, Cymbopogon citrates and Annona muricata were screened for antibacterial activities at 200mg/ml concentration. Antibacterial efficacy of extracts against the bacteria were identified by gram staining techniques, coagulase and catalase tests and the bacterial isolate was indicated by the appearance of clear zones of inhibition around the disks. The extracts of Vernonia amygdalina and Ocimum gratissimum showed inhibitory activities against the bacterial isolate with zones of inhibition of 12mm and 8.5mm respectively while

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5

A., I. Nta, E. Agbo B., and S. Udoekong N. "Bio-insecticidal and Grain Protectant Activities of Mixed Powder of Ocimum gratissimum and Vernonia amydalina against Callosobruchus maculatus (Coleoptera: Bruchidae) in Calabar, Nigeria." Asian Journal of Biology 2, no. 3 (2017): 1–7. https://doi.org/10.9734/AJOB/2017/33500.

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The bio-insecticidal and grain protectant activities of mixed powder of <em>Ocimum gratissimum</em> and <em>Vernonia amygdalina </em>upon <em>Callosobruchus maculatus</em> was carried out in Calabar, Nigeria during the dry season (August to November) of 2015. The mortality rate of cowpea weevil treated <em>V. amygdalina</em>: <em>O. gratissimum</em> at 100: 0 concentrations were 17.0%, 27.0%, and 47.0% for a period of 24hrs, 48hrs and 72hrs, respectively. Concentrations 0:100 gave a percentage mortality of 47.0%, 67.0% and 73.0% at 24hrs, 48hrs and 72hrs, respectively. 80: 20 and 20: 80 concen

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6

Nta, A., B. Agbo, and N. Udoekong. "Bio-insecticidal and Grain Protectant Activities of Mixed Powder of Ocimum gratissimum and Vernonia amydalina against Callosobruchus maculatus (Coleoptera: Bruchidae) in Calabar, Nigeria." Asian Journal of Biology 2, no. 3 (2017): 1–7. http://dx.doi.org/10.9734/ajob/2017/33500.

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7

James, Stephen, Efe Omwirhiren, Istifanus Joshua, Iliyasu Suleiman, and Joseph Endas. "In vitro and In vivo Assessment of the Anti-diabetes Potentials of Murraya koenigii, Hibiscus cannabinus, Vernonia amydalina and Telfairia occidentalis Leave Extract." International Journal of Biochemistry Research & Review 15, no. 1 (2016): 1–11. http://dx.doi.org/10.9734/ijbcrr/2016/30494.

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8

Ogunjinmi, Oluwasayo Esther, Olumayowa Vincent Oriyomi, and Adedoyin Adetutu Olasunkanmi. "Phytochemical, Antioxidant and Anti-diabetic Potentials of the Ethanol Leave Extracts of four Medicinal Plants." European Journal of Medicinal Plants 34, no. 5 (2023): 1–11. http://dx.doi.org/10.9734/ejmp/2023/v34i51135.

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For many years, medicinal plants have been a resource for healing in several local communities around the world and the phytochemicals in them such as flavonoids, alkaloids, phenolic, tannins, and terpenoids are attributed to their many medicinal values. Vernonia amydalina, Senna alata, Jatropha curcas, and Grewia pubescens are important plants with immense value. In this study, phytochemical screening, antioxidant analysis and the potential anti-hyperglycemic properties of the plants was investigated in-vitro. The ethanol leave extracts of the plants were subjected to qualitative phytochemica

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9

Auwal, Musa M., Jibrin M. Yelwa, Ibrahim Abubakar, Jamilu B. Umar, Hussaina G. Anchau, and Fatima B. Tanimu. "The Levels of Antinutritional Factors in Moringa Oleifera and Vernomia Amygdalina Leaves Found in Some Part of Plateau State, Nigeria." Oriental Journal of Physical Sciences 4, no. 2 (2020): 65–69. http://dx.doi.org/10.13005/ojps04.02.06.

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In this research work, various materials were used and they include; apparatus such as fume cupboard, measuring cylinder, spatula, centrifuge, pipette and reagent such as Na2CO3, CaCl2, H2SO4, HCl, AgNO3. The nutrient composition of V. Amydalina are: Phytate 11.9 ± 0.01 (mg/100g), oxalate 244.02 ± 0.57 (mg/100g), tannins 1.28 ± 0.50 (mg/100g), alkaloid 1.66 ± 0.01%, HCN 2036.00 ± 0.58 (mg/100g) and M. oleifera are: phytate 10.58 ± 0.01 (mg/100g), oxalate 334.33 ± 0.67 (mg/100g), tannin 8.19 ± 0.01 (mg/100g), alkaloid 1.72 ± 0.01% and HCN 3998.30 ± 0.49 (mg/100g). These results showed that V. A

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10

Nitonye, Samson, Umoh Ofonime Emmanuel, and A. Ogbonnaya Ezenwa. "Combating Corrosion in Transmission Pipelines in Marine Environment Using Vernomia Amydalina as Inhibitor." Open Journal of Marine Science 08, no. 04 (2018): 450–72. http://dx.doi.org/10.4236/ojms.2018.84025.

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11

Oladele, Johnson Olaleye, Oyedotun Moses Oyeleke, Boyede Dele Olowookere, et al. "Bitter Leaf (Vernonia Amygdalina) Modulates Nitrobenzene-Induced Renal Damage in Rats Via Suppression of Oxido-Inflammatory Activities." Serbian Journal of Experimental and Clinical Research, March 13, 2021. http://dx.doi.org/10.2478/sjecr-2020-0040.

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Abstract Renal diseases have been documented as one of the massive health challenges, ranked as the 12th most common cause of death globally. This study was carried out to assess the chemopreventive effects of Vernonia amydalina on nitrobenzene mediated renal damage in rats. Rats were exposed to 100 mg/kg body weight of nitrobenzene via oral administration and treated with 200 mg/kg body weight (BW) and 400 mg/kg BW of methanol leaf extract of Vernonia amydalina (MLVA) and Vitamin E for 14 consecutive days. Nitrobenzene significantly induced a renal injury with a significant increase in the se

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12

E. Andy, Iniobong, Ekomobong A. Okpo, and Christiana E. Ubengama. "In-vitro Susceptibility Profile of Pseudomonas aeruginosa to Selected Medicinal Plants Obtained from University of Calabar Farm, Nigeria." Annual Research & Review in Biology, January 27, 2022, 85–91. http://dx.doi.org/10.9734/arrb/2022/v37i130481.

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Antibiotic resistance represents the greatest challenges to global health. Strategies to curb the menace of antibiotic resistance include researching for new antimicrobials from plants. This study is aimed at determine the in-vitro susceptibility of Pseudomonas aeruginosa to Chromolaena odorata, Jatropha tanjorensis, Ocimum gratissimum, Vernonia amydalina, Hibiscus sabdariffa and Aloe barbadensis obtained within University of Calabar farm. All the test carried out were performed according to standard microbiological procedure. Ethanol was used for extraction of Phytochemicals and were purified

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13

"MAJOR COMPONENT AND ANTIMICROBIAL ACTIVITY OF THE EXTRACT OF BITTER LEAF (Vernonia amydalina) AGAINST Vibrio parahaemolyticus." Journal of Animal and Plant Sciences, no. 1 (December 21, 2024). https://doi.org/10.36899/japs.2025.1.0004.

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14

Leelee, Famii Zitte and Friday Robinson Nuanae. "Effects of Methanolic Extract of Bitter leaf (Vernonia amygdalina) on the Neuromuscular functions of Albino rats. (Rattus norvegicus)." April 17, 2023. https://doi.org/10.5281/zenodo.7834852.

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This research was conducted to determine the effects of methanolic extract of bitter on the neuromuscular system of albino rats. Twenty–five (25) albino rats were grouped into five groups (A, B, C, D and E) of five (5) rats per group. Group A served as control while groups B, C, D and E were treated with  different concentrations of methanolic extract of bitter leaf (100mg/kg/day, 200mg/kg/day, 400mg/kg/day and 800mg/kg/day) at two different times (morning and evening with half the daily dose per administration) respectively for a period of one-month. Thereafter the rats were subjec

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15

Abimbola, Ogunsola Oluseyi, and Great Alabi. "Vernonia amydalina leaf extract ameliorates hyperandrogenism and oxidative stress in polycystic ovarian syndrome-induced Sprague-Dawley rats." Endocrine Abstracts, October 27, 2022. http://dx.doi.org/10.1530/endoabs.86.p272.

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16

Osaretin, Buraimoh Samuel, and Adeniyi Adejoke Deborah. "Physicochemical Properties of Selected Local Medicinal Soups Consumed in Southwest Nigeria." Journal of Medicine and HealthCare, June 30, 2020, 1–6. http://dx.doi.org/10.47363/jmhc/2021(3)147.

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Cottonseed (Gossypium herbaceum), bitter leaf (Vernonia) amydalina), cashew leaf (Anacardium occidentale), Piper nigrum (black pepper) and scent leaf (Ocimumgratissimum) are major ingredients used in preparation of the local soups namely; ‘koroowu soup’, ‘black soup’, ‘cashew leaf soup’ and ‘ewe luje soup’ consumed in certain parts of Nigeria. The ingredients for the soups were sorted according to the local preparations, separately blended into a paste and were either cooked or uncooked. The pastes were subjected to physicochemical (proximate, pH, total titratable acidity, mineral, phytochemic

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17

Kate, Imafidon E., and Okunrobo O. Lucky. "Effects of Vernonia amygdalina Del. Extract on Cholesterol Level and Lipid Peroxidation Status in Rats Given Red Dye Adulterated Palm Oil Diets." May 15, 2012. https://doi.org/10.5281/zenodo.9236.

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Aims: To evaluate the effects of aqueous extract of V. amygdalina on lipid profile and lipid peroxidation status in rats. Study Design: Experimentation. Place and Duration of Study: Departments of Biochemistry and Pharmaceutical Chemistry, University of Benin, Benin city, Nigeria. From February, 2011 to November, 2011. Methodology: Biochemical analyses were carried out to determine the activities of liver and plasma catalase, superoxide dismutase (SOD) and levels of malondialdehyde, total cholesterol, high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol. Consequently, f

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18

Angupale, Jimmy R., Jonans Tusiimire, and Ndidi C. Ngwuluka. "A review of efficacy and safety of Ugandan anti-malarial plants with application of RITAM score." Malaria Journal 22, no. 1 (2023). http://dx.doi.org/10.1186/s12936-023-04486-6.

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Abstract Background Malaria, a treatable disease mainly caused by Plasmodium falciparum has remained a health challenge in Africa, a continent that accounted for 96% of total global cases and deaths in 2021. Uganda, a malaria endemic country is experiencing malaria parasite resistance to some of the drugs used in the artemisinin-based combination therapy (ACT). In an effort to prioritize herbal medicines for new product development, this review synthesized the available safety and efficacy literature on the Ugandan anti-malarial plants to suggest most effective herbal plants. Methods Literatur

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19

Ugwu, Melvin Nnaemeka, Atamgba Agbor Asuk, Mbeh Ubana Eteng, and Edward Odey Emuru. "Evaluation of Impact of Some Selected Plants on Haematological Parameters of Testosterone and Estradiol Induced Benign Prostatic Hyperplasia Adult Male Rats." International Blood Research & Reviews, December 4, 2019, 1–15. http://dx.doi.org/10.9734/ibrr/2019/v10i130113.

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Background: Benign prostate hyperplasia (BPH) is an age-related disease of unknown etiology, characterized by prostate enlargement. The effect of Prosopis africana (PA), Vernonia amydalina (VA) and Ocimum gratissmum (OG), plant extracts on haematological parameters of BPH animal model was investigated. Methods: BPH was induced in 45 male Wistar rats (250-350 g) by exogenous injection of testosterone and estradiol in staggered doses for 3 weeks. To confirm BPH induction, some animals were sacrificed; histological inspection of prostate gland and PSA was carried out. Forty BPH induced rats

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