Log in

Relevant bibliographies by topics / Vernonia amygdalina / Journal articles

To see the other types of publications on this topic, follow the link: Vernonia amygdalina.

Journal articles on the topic 'Vernonia amygdalina'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Vernonia amygdalina.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Putri, Adira Aulia, Irdat Mukaromah, Novi Dwi Pratiwi, and Galih Noor Alivian. "UTILIZATION OF AFRICAN LEAVES (VERNONIA AMYGDALINA) TO LOWER BLOOD PRESSURE IN PATIENTS WITH HYPERTENSION: A SYSTEMATIC REVIEW." International Journal of Biomedical Nursing Review 1, no. 1 (2022): 52. https://doi.org/10.20884/1.ijbnr.2022.1.1.6534.

Full text

Abstract:

Introduction: Hypertension is a non-communicable disease caused by genetics, stress, and lack of physical activity. So far, no effective drugs have been found to cure high blood pressure. Vernonia amygdalina contains substances that can lower blood pressure, namely flavonoids and potassium. Purpose: The systematic review aims to assess the potential of vernonia amygdalina in lowering blood pressure in hypertensive people. Methods: Articles are obtained from electronic databases such as PubMed, ScienceDirect, and Google Scholar published from 2011 to 2021. Keywords used: ("African leaf" OR "bit

APA, Harvard, Vancouver, ISO, and other styles

2

Aulannisa, Fidya, Isnaini Nur Jannah, Erna Ayu Wulandari, Vira Cesar Oktaviani, and Eka Saputri. "Systematic Review Perbandingan Efektifitas Daun Insulin (Smallanthus sonchifolius) dan Daun Afrika (Vernonia amygdalina) dalam Penurunan Kadar Gula Darah Tikus Diabetes." Generics: Journal of Research in Pharmacy 1, no. 2 (2021): 70–78. http://dx.doi.org/10.14710/genres.v1i2.11148.

Full text

Abstract:

Objective: Diabetes Melitus (DM) adalah penyakit ditandai dengan kadar glukosa darah sewaktu sama atau lebih dari 200 mg/dl, dan kadar glukosa darah puasa di atas atau sama dengan 126 mg/dl. Daun pada tanaman insulin atau yacon (Smallanthus sonchifolius) dan tanaman afrika (Vernonia amygdalina Del.) telah diketahui memiliki kemampuan menurunkan kadar glukosa darah. Penulisan systemtic review ini bertujuan untuk mengetahui perbedaan penurunan kadar glukosa darah tikus putih yang diberi perlakuan daun insulin (Smallanthus sonchifolius) dan daun afrika (Vernonia amygdalina Del).Metode: Pencarian

APA, Harvard, Vancouver, ISO, and other styles

3

Prananda, Arya Tjipta, Aminah Dalimunthe, Urip Harahap, et al. "Vernonia amygdalina protects against doxorubicin-induced hepatic and renal damage in rats: mechanistic insights." Pharmacia 70, no. 3 (2023): 825–35. http://dx.doi.org/10.3897/pharmacia.70.e112425.

Full text

Abstract:

The use of the chemotherapeutic agent doxorubicin is limited due to its potential to cause signifi-cant hepatorenal damage. The present study aimed to investigate the potential hepatoprotective and nephroprotective effects of Vernonia amygdalina, a medicinal plant with known antioxidant and anti-inflammatory properties, against doxorubicin-induced toxicity in rats. Male Wistar rats were randomly divided into four groups: Control, Doxorubicin (DOX), DOX + Vernonia Amyg-dalina (DOX+VA), and Vernonia amygdalina (VA) alone. DOX and DOX+VA groups were treated with a single intraperitoneal injection

APA, Harvard, Vancouver, ISO, and other styles

4

Prananda, Arya Tjipta, Aminah Dalimunthe, Urip Harahap, et al. "Vernonia amygdalina protects against doxorubicin-induced hepatic and renal damage in rats: mechanistic insights." Pharmacia 70, no. (3) (2023): 825–35. https://doi.org/10.3897/pharmacia.70.e112425.

Full text

Abstract:

The use of the chemotherapeutic agent doxorubicin is limited due to its potential to cause signifi-cant hepatorenal damage. The present study aimed to investigate the potential hepatoprotective and nephroprotective effects of Vernonia amygdalina, a medicinal plant with known antioxidant and anti-inflammatory properties, against doxorubicin-induced toxicity in rats. Male Wistar rats were randomly divided into four groups: Control, Doxorubicin (DOX), DOX + Vernonia Amyg-dalina (DOX+VA), and Vernonia amygdalina (VA) alone. DOX and DOX+VA groups were treated with a single intraperitoneal injection

APA, Harvard, Vancouver, ISO, and other styles

5

Son, Hoang Le, Ha Nguyen Anh Tu, and Tran Van Minh. "Ameliorative Potentials of Vernonia amygdalina on Acetaminophen-induced Acute Liver Injury in Mice." Asian Journal of Biotechnology and Bioresource Technology 9, no. 2 (2023): 22–35. http://dx.doi.org/10.9734/ajb2t/2023/v9i2180.

Full text

Abstract:

Aims: To investigate the ameliorative potentials of Vernonia amygdalina on acetaminophen-induced liver injury in mice. Methodology: Acetaminophen-induced acute liver injury was conducted on Swiss-albino mice weighing 25 - 30 g. Group A was maintained as a negative control (healthy liver) while group B was assigned as a positive control (damaged liver). Group C, D and E were orally administered 100 mg/kg, 200 mg/kg and 400 mg/kg of dried Vernonia amygdalina leaf extract, respectively. Meanwhile, group F, G and H were orally administered 100 mg/kg, 200 mg/kg and 400 mg/kg of fresh Vernonia

APA, Harvard, Vancouver, ISO, and other styles

6

Oseghale, Ikalo David, Olabisi Promise Lawal, Daniel Osezuwa Ubebe, et al. "Ethnomedicinal and Phytopharmacological Aspects of Vernonia amygdalina (Bitter Leaf) Utilized as a Traditional Medicinal Herb." Asian Journal of Research in Biochemistry 14, no. 6 (2024): 41–57. http://dx.doi.org/10.9734/ajrb/2024/v14i6326.

Full text

Abstract:

Vernonia amygdalina Delile, commonly known as “bitter leaf,” is a shrub in the Asteraceae family, widely seen in tropical regions of Africa. Vernonia amygdalina is found to be traditionally used in African medicine. Various parts of this plant, especially the leaves, are utilized to treat ailments such as fever, diabetes, and gastrointestinal issues. Research from multiple researchers has shown a wide range of phytochemical and bioactive compounds present in Vernonia amygdalina; examples are terpenoids, tannins, alkaloids, saponins, flavonoids, steroids, glycosides, etc., which have contribute

APA, Harvard, Vancouver, ISO, and other styles

7

Usunomena, U., N. Paulinus Okolie, and I. Gerald Eze. "Inhibitory Effect of Vernonia amygdalina on Dimethylnitrosamine (DMN)-induced Liver Fibrosis in Rats." International Journal of Clinical Pharmacology & Toxicology (IJCPT) 4, no. 4 (2015): 179–84. https://doi.org/10.19070/2167-910X-1500030.

Full text

Abstract:

In this study, the protective effect of Vernonia amygdalina ethanolic leaf extract against hepatic fibrosis induced by repeated intermittent administration of Dimethylnitrosamine (DMN) was investigated in rats. A total of 48 rats divided into 4 groups were used. Group 1 served as control, Group 2 received 200mg/kg Vernonia amygdalina only for 14days, Group 3 received 200mg/kg Vernonia amygdalina for 14 days followed by intraperitoneal administration of 10mg/kg DMN on first three days of each week for 2 weeks, while Group 4 received intraperitoneal administration of 10mg/kg

APA, Harvard, Vancouver, ISO, and other styles

8

Harefa, Herman Syukur, Poppy Anjelisa Zaitun Hasibuan, and Urip Harahap. "Cytotoxic and Apoptotic Activities of Vernonia amygdalina Extract in HepG2 Cell Line." Indonesian Journal of Pharmaceutical and Clinical Research 5, no. 2 (2022): 24–29. http://dx.doi.org/10.32734/idjpcr.v5i2.6350.

Full text

Abstract:

Liver cancer is a malignant tumor originating from the development of chronic hepatitis or cirrhosis and is responsible for damage to the shape and function of the liver. The loss of the ability of conventional chemotherapy to inhibit the growth of cancer cells is a major focus in the world. Natural ingredients are the solution to this problem, for example the use of Vernonia amygdalina leaves. Vernonia amygdalina contains flavonoids, cardiac glycosides, and steroids/triterpenoids which are reported to have anticancer properties. This study aims to examined the activity of these plants as anti

APA, Harvard, Vancouver, ISO, and other styles

9

Fitriani, Nyayu, Kamalia Layal, and Kamila Kamila. "Aktivitas Antidiabetes Kombinasi Ekstrak Etanol Daun Andrographis Paniculata dan Vernonia Amygdalina." Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan 7, no. 2 (2017): 104. http://dx.doi.org/10.32502/sm.v7i2.1371.

Full text

Abstract:

Diabetes mellitus merupakan sekelompok penyakit metabolik yang ditandai dengan hiperglikemia kronik yang diakibatkan oleh defek pada sekresi insulin, aksi insulin atau keduanya. Daun Andrographis paniculata dan Vernonia amygdalina merupakan tanaman yang dapat digunakan sebagai pengendali kadar gula dalam darah. Penelitian ini bertujuan untuk mengetahui efektivitas kombinasi ekstrak kedua daun dibandingkan dengan acarbose dalam menurunkan kadar gula darah postprandial tikus diabetes. Penelitian ini adalah penelitian eksperimental, dengan pre dan post test control group design. Tikus diinduksi d

APA, Harvard, Vancouver, ISO, and other styles

10

Hsu, Chia-Fang, Fu-An Yang, Shih-Chuan Liu, et al. "Protective Role of Vernonia Amygdalina Leaf Aqueous Extract Against Neomycin-Induced Hair Cell Damage in Transgenic Zebrafish." Current Topics in Nutraceutical Research 18, no. 4 (2020): 366–72. http://dx.doi.org/10.37290/ctnr2641-452x.18:366-372.

Full text

Abstract:

Aminoglycoside treatment increases the loss of hair cells in the inner ear. Once the hair cells are lost, they are unable to regenerate spontaneously, and the resulting hearing loss is profound and irreversible in humans. The aqueous extract from the leaves of Vernonia amygdalina has been reported to have antioxidant properties. In this study, we evaluated whether the aqueous extracts of Vernonia amygdalina leaf could protect hair cells from aminoglycoside-induced damage using a transgenic zebrafish line. Our results showed that the EC<sub>50</sub> of 1,1-Diphenyl-2 picrylhydrazyl radical scav

APA, Harvard, Vancouver, ISO, and other styles

11

Ahamefula Sunday Ezekwe, Karibo Amakiri Okari, Peter Gift Wokocha, Mike Tochi Achor, and Boma Ngo Fubara. "Evaluating alloxan-induced diabetic rats." International Journal of Science and Research Archive 13, no. 2 (2024): 3544–52. https://doi.org/10.30574/ijsra.2024.13.2.2499.

Full text

Abstract:

The increasing incidence of diabetes and the adverse effects of chemical medications underscore the importance of exploring alternative non-pharmacological treatments. Vernonia amygdalina, a widely utilized medicinal herb, shows promising therapeutic potential. This study investigated the impact of aqueous leaf extracts of Vernonia amygdalina on various biochemical parameters in alloxan-induced diabetic rats. Diabetes was induced in male Wistar rats through intraperitoneal injection of alloxan (150 mg/kg). The rats were then randomly divided into four groups: Group 1 (normal control), Group 2

APA, Harvard, Vancouver, ISO, and other styles

12

Usunobun, Usunomena, and Okolie Ngozi. "Phytochemical analysis and proximate composition of Vernonia amygdalina." International Journal of Scientific World 4, no. 1 (2016): 11. http://dx.doi.org/10.14419/ijsw.v4i1.5845.

Full text

Abstract:

<p><strong>Background:</strong> <em>Vernonia amygdalina</em> is used to prepare dishes as well as a multi-purpose fodder tree with high biomass yield. This study was conducted to determine phytochemicals and proximate composition of <em>Vernonia amygdalina</em> leaves.</p><p><strong>Methods:</strong> Evaluation of <em>Vernonia amygdalina</em> for phytochemicals and proximate composition were conducted using standard methods.</p><p><strong>Results:</strong> Result showed that <em>Vernonia

APA, Harvard, Vancouver, ISO, and other styles

13

Abdulrahman, A., M. G. Garba, S. Gaddafi, and A. Yusuf. "RESPONSE OF YANKASA RAMS TO VARIOUS INCLUSION LEVELS OF PROPAGATED BITTER LEAF (Vernonia amygdalina) ON PERFORMANCE AND RUMEN ECOLOGY." FUDMA Journal of Animal Production and Environmental Science 1, no. 1 (2025): 46–51. https://doi.org/10.33003/japes.2025.v1i1.46-51.

Full text

Abstract:

The experiment evaluated the response of Yankasa rams fed graded levels of propagated Bitter Leaf (Vernonia amygdalina) on growth performance, nutrient digestibility, rumen ecology, and blood profile. Twenty (20) rams were randomly allocated into four dietary treatments consisting of 0%, 5%, 10%, and 15% inclusion levels of dry bitter leaf. Growth performance, nutrient digestibility trail and rumen fluid were collected and analyzed accordingly. Data obtained were analyzed using statistical analysis system (SAS,2002). Growth performance results showed that T3(15%) had an outstanding (P<0.05)

APA, Harvard, Vancouver, ISO, and other styles

14

Ikbal, Abu Md Ashif, Amlanjyoti Rajkhowa, P. Chinglemba Singh, Paromita Dutta Choudhury, and Ram Kumar Sahu. "Assessment of Phytochemical and Anthelmintic Activity of Some Selected Ethnomedicinal Plants from Barak Valley Region of Assam." Biomedical and Pharmacology Journal 13, no. 4 (2020): 1825–31. http://dx.doi.org/10.13005/bpj/2057.

Full text

Abstract:

Since ancient times it has been observed that the ethnomedicinal knowledge is backbone of rural healthcare. The traditional healers of Barak Valley region of Assam used traditional medicine for the treatment of various diseases including helminths infection. Hence the current study was planned to explore the traditional medicines namely Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordica charantia used as anthelmintic activity by the local people of Barak Valley region of Assam. The decoction of leaves of Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordi

APA, Harvard, Vancouver, ISO, and other styles

15

Ikbal, Abu Md Ashif, Amlanjyoti Rajkhowa, P. Chinglemba Singh, Paromita Dutta Choudhury, and Ram Kumar Sahu. "Assessment of Phytochemical and Anthelmintic Activity of Some Selected Ethnomedicinal Plants from Barak Valley Region of Assam." Biomedical and Pharmacology Journal 13, no. 4 (2020): 1825–31. http://dx.doi.org/10.13005/bpj/2057.

Full text

Abstract:

Since ancient times it has been observed that the ethnomedicinal knowledge is backbone of rural healthcare. The traditional healers of Barak Valley region of Assam used traditional medicine for the treatment of various diseases including helminths infection. Hence the current study was planned to explore the traditional medicines namely Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordica charantia used as anthelmintic activity by the local people of Barak Valley region of Assam. The decoction of leaves of Justicia adhatoda, Vernonia amygdalina, Mikania micrantha and Momordi

APA, Harvard, Vancouver, ISO, and other styles

16

Maulana, Maulana Zulkarnain Imansyah, and Atriana Zain. "Uji Efektivitas Sediaan Krim Ekstrak Etanol Daun Afrika (Vernonia amygdalina Del.) Terhadap Bakteri Propionibacterium acnes." Jurnal Kesehatan Yamasi Makassar 7, no. 1 (2023): 81–88. http://dx.doi.org/10.59060/jurkes.v7i1.239.

Full text

Abstract:

Daun Afrika (Vernonia amygdalina Del.) atau yang dulu disebut “Daun Pahit” merupakan salah satu varietas tanaman yang digunakan sebagai obat herbal. Daun afrika berkhasiat sebagai antibakteri, antijamur, antialergi, antioksidan, analgesik dan antiinflamasi. Daun afrika mengandung metabolit sekunder seperti flavonoid, saponin, tanin, steroid, terpenoid. Penelitian ini bertujuan untukmengetahui efektivitas sediaan krim ekstrak etanol daun Afrika (Vernonia amygdalina Del.) terhadap bakteri Propionibacterium acnes. Penelitian ini dilakukan dengan metode Eksperimental Laboratorium. Di buat krim eks

APA, Harvard, Vancouver, ISO, and other styles

17

Anifowose, Oluwagbenga, Bitrus W. Tukura, and Obaje D. Opaluwa. "Detoxification Efficiency of Ethanolic Leaf Extracts of Moringa oleifera and Vernonia amygdalina on Aflatoxin B1 in Rice and Maize." International Journal of Scientific Research in Chemical Sciences 12, no. 2 (2025): 1–6. https://doi.org/10.26438/ijsrcs.v12i2.187.

Full text

Abstract:

The prevalence of aflatoxin B1 in stored agricultural produce and their subsequent effect on food safety has stepped up researches to identify novel phytoremediation techniques. This research evaluates the potency of phytochemical remediation on aflatoxin B1 (AFB1) in stored rice and maize using ethanolic leaf extracts of Moringa oleifera and Vernonia amygdalina. HPLC-UV/Vis spectroscopy was employed in the determination of the detoxification levels of the AFB1 in the samples. Phytochemical constituents in the plant extracts were quantified using standard methods. Phytochemical concentrations

APA, Harvard, Vancouver, ISO, and other styles

18

Usunobun, Usunomena, and Gabriel Anyanwu. "Dimethylnitrosamine (DMN) pre-treated rats and protective effect of Vernonia amygdalina post-treatment on liver function." International Journal of Pharmacology and Toxicology 4, no. 1 (2016): 74. http://dx.doi.org/10.14419/ijpt.v4i1.6065.

Full text

Abstract:

Background: Liver disease and toxicity is common, especially with many drug treatments. The effect of Vernonia amygdalina ethanolic leaf extract post-treatment on rats pre-treated with dimethylnitrosamine (DMN) was evaluated.Methods: Male wistar rats were orally administered DMN (single dose of 25 mg/kg) on first day and thereafter post-treated with 100 and 200mg/kg ethanolic leaf extract of Vernonia amygdalina for seven days. Analysis of serum concentrations of albumin, total protein, total bilirubin and glucose were carried out.Results: Administration of DMN alone to rats significantly incre

APA, Harvard, Vancouver, ISO, and other styles

19

Uthman H. "Kinetic Studies on the Inhibition Potential of Bitter Leaf (Vernonia Amygdalin) in the Management of Diabetes." GSC Advanced Research and Reviews 21, no. 3 (2024): 184–97. https://doi.org/10.30574/gscarr.2024.21.3.0483.

Full text

Abstract:

The aim of this study was to investigate the inhibition potential of extracts from Vernonia amygdalina on α-amylase and α-glucosidase activity, and its useful mechanisms in the treatment of diabetes specifically Type 2. The searchlight is beamed on the potential of the plant extract to inhibit the activity of α-amylase and thereby determining its mechanism or mode on inhibition as well as its IC50 value. The inhibition of alpha-amylase and alpha-glucosidase enzymes is a key strategy in managing diabetes. Vernonia amygdalina is a natural plant extract that has been used traditionally to manage

APA, Harvard, Vancouver, ISO, and other styles

20

Tedla, Abebe, Tesfaye Sharew, Minbale Gashu, and Belete Tewabe. "Comparative Study of the Phytochemical Constituents and Antibacterial Activity of Vernonia amygdalina and Moringa oleifera Crude Extracts." BERHAN INTERNATIONAL RESEARCH JOURNAL OF SCIENCE AND HUMANITIES 8, no. 1 (2024): 62–81. https://doi.org/10.61593/dbu.birjsh.01.08.04.

Full text

Abstract:

Vernonia amygdalina Amharic vernacular name “Grawa” and Moringa oleifera Amharic vernacular name “Shiferaw”, are the most common traditional medicinal plants used in Ethiopia. The parts of these plants such as stem bark, leaves and flowers showed varieties of medicinal properties and cure various human and animal diseases and ailments. The purpose of this study was to investigate the antibacterial activity and the phytochemical constituents of the crude extracts of Vernonia amygdalina and Moringa oleifera. Maceration technique was employed to obtain crude extracts from the various parts of the

APA, Harvard, Vancouver, ISO, and other styles

21

ZAHRA, IKLILA. "UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN AFRIKA (Vernonia amygdalina Del.) TERHADAP BAKTERI Escherichia coli ATCC 25922 SECARA In Vitro." MEDFARM: Jurnal Farmasi dan Kesehatan 10, no. 1 (2021): 28–34. http://dx.doi.org/10.48191/medfarm.v10i1.52.

Full text

Abstract:

Obat tradisional merupakan bahan atau ramuan berupa tumbuhan, bahan hewan atau bahan lainnya. Salah satu contoh obat tradisional adalah Tanaman Daun Afrika (Vernonia amygdalina Del.). Daun Afrika (Vernonia amygdalina Del.) memiliki beberapa kandungan kimia seperti Flavanoid, alkaloid, tanin dan kandungan kimia lainnya yang diyakini berkhasiat untuk pengobatan beberapa penyakit seperti diabetes, hipertensi, asam urat dan antibakteri. Tujuan: Penelitian ini bertujuan untuk mengetahui potensi antibakteri pada Escherichia coli dengan menggunakan metode difusi cakram. Hasil Penelitian : Zona hambat

APA, Harvard, Vancouver, ISO, and other styles

22

M. Muhammad, E.D. Putra, H. Cintya, and D. Satria. "THE EFFECT OF SOLVENT TOWARDS ANTIOXIDANT ACTIVITY OF Vernonia amygdalina Delile LEAVES." RASAYAN Journal of Chemistry 16, no. 02 (2023): 760–65. http://dx.doi.org/10.31788/rjc.2023.1628059.

Full text

Abstract:

Antioxidants guard against reactive oxygen free radicals. Antioxidants neutralize free radicals by adding electrons to them, preventing bodily harm. African leaves (Vernonia amygdalina Delile.) contain an antioxidant. African leaves are the leaves of a thousand diseases because they have pharmacological effects on various diseases. African leaves contain steroids/triterpenoids, glycosides, saponins, tannins, and flavonoids. This study examined Vernonia amygdalina Delile. leaf combination ethanol extract antioxidant properties. The extracts were prepared with the reflux method using methanol, b

APA, Harvard, Vancouver, ISO, and other styles

23

Raimi, C. O., W. A. Oyelade, and A. O. Iyanda. "Histopathological effect of aqueous bitter leaf extract (Vernonia amygdalina) on acetaminophen-induced liver damage in albino rat (Rattus norvegicus)." Nigerian Journal of Animal Production 47, no. 4 (2020): 24–31. http://dx.doi.org/10.51791/njap.v47i4.95.

Full text

Abstract:

Liver diseases are a worldwide problem. Medicinal plants are being increasingly utilized to treat a wide variety of diseases, liver disorder inclusive. The effect of aqueous leaf extracts of Vernonia amygdalina on acetaminophen-induced liver damage via the assessment of the histopathological examination was examined. Five groups of albino rats were used (n = 5). Animals in group 1 were fed normal laboratory pellet and water ad libitum (Control); those in group 2 received 3000mg/kg of acetaminophen alone. Groups 3, 4 and 5 received 3000mg/kg of acetaminophen and in addition 50mg/kg Vernonia amy

APA, Harvard, Vancouver, ISO, and other styles

24

Alege, Gbenga Olorunshola, Musa Ozigi Yakubu, Deborah Tini Egilla, David Franklin Igata, Usman Ibrahim Aliyu, and Danlami Dauda. "GROWTH AND YIELD RESPONSE OF SESAME (SESAMUM INDICUM L.) TO BITTER LEAF (VERNONIA AMYGDALINA DEL.) LEAF, STEM AND ROOT AQUEOUS EXTRACTS." FUDMA JOURNAL OF SCIENCES 5, no. 4 (2022): 150–56. http://dx.doi.org/10.33003/fjs-2021-0504-798.

Full text

Abstract:

This study was carried out to assess the effect of leaf, stem and root aqueous extracts of Vernonia amygdalina on seed germination, growth and yield performance of Sesamum indicum. The aqueous extracts of the three plant parts were applied at concentrations of 25%, 50%, 75%, and 100% to sesame seeds in petri dish and compared with seeds treated with distilled water (control). The percentage of germinated seeds and lengths of radicle and plumule were measure within 10 days of sowing. The different concentrations of leaf, stem and root extracts of Vernonia amygdalina were applied to the seedling

APA, Harvard, Vancouver, ISO, and other styles

25

Hasibuan, Poppy Anjelisa Zaitun, Rasme Kita Uli Arihta Br Sitorus, Adam Hermawan, Fathul Huda, Syukur Berkat Waruwu, and Denny Satria. "Anticancer activity of the ethylacetate fraction of Vernonia amygdalina Delile towards overexpression of HER-2 breast cancer cell lines." Pharmacia 71 (June 5, 2024): 1–8. http://dx.doi.org/10.3897/pharmacia.71.e125788.

Full text

Abstract:

Vernonia amygdalina Delile, coming from the Asteraceae tribe, contains active compounds that can treat breast cancer. This study examines the anticancer activity of Vernonia amygdalina Delile leaves, an active fraction of MCF-7/HER-2 breast cancer cells. Thin-layer chromatography determines the phytochemical screening. Cytotoxic and proliferation analyses were determined using the MTT method for the MCF-7/HER-2 breast cancer cell line. The cell cycle and apoptosis profiles were examined using flow cytometry. The results can be summarized in this study: Vernonia amygdalina Delile fraction conta

APA, Harvard, Vancouver, ISO, and other styles

26

Enogieru, A. B., and F. O. Egbon. "Neurobehavioural and Histological Alterations in Lead Acetate-Exposed Rats Pretreated with Aqueous Leaf Extract of Vernonia amygdalina." African Journal of Biomedical Research 25, no. 2 (2022): 205–13. http://dx.doi.org/10.4314/ajbr.v25i2.14.

Full text

Abstract:

Lead is a systemic toxicant that affects virtually every organ system, primarily the central nervous system, through an increase in the production of reactive oxygen species (ROS). This increase in ROS overwhelms the natural antioxidant system of the body leading to oxidative stress. Some plants such as Vernonia amygdalina have been reported to possess antioxidant activity which counteracts the damage induced by free radicals. Accordingly, this study was designed to investigate the possible protective activity of aqueous Vernonia amygdalina leaf extract against lead-induced neurotoxicity in ad

APA, Harvard, Vancouver, ISO, and other styles

27

Liu, Xiangzhong, Mi Zhou, Shoulun He, et al. "Polyhydric Stigmastane-Type Steroids Derivative from Vernonia amygdalina and Their Anti-Neuroinflammatory Activity." Pharmaceuticals 15, no. 9 (2022): 1160. http://dx.doi.org/10.3390/ph15091160.

Full text

Abstract:

Vernonia amygdalina Del. is a traditional medicinal plant and vegetable originating from tropical Africa. The phytochemical investigation of V. amygdalina led to eight undescribed polyhydric stigmastane-type steroids, vernonin M–T (1–8). Their gross structures and stereochemistry were elucidated by HR-ESI-MS, 1D and 2D NMR spectra, X-ray diffraction, quantum chemical computation of the ECD spectrum, and the in situ dimolybdenum CD method. The anti-neuroinflammatory activity of the isolated compounds was performed in BV-2 microglia cells. As a result, compound 1 displayed a notable anti-neuroin

APA, Harvard, Vancouver, ISO, and other styles

28

Adoyi, Michael Paul, Ubelejit Alfred John, Ladan Muhammad Suwaiba, Samuel Terhide Tyohemba, Vawanje Bitrus Kwaya, and Asugu Mary Mbahi. "COMPARATIVE EVALUATION OF THE ANTIBACTERIAL EFFICACY AND PHYTOCHEMICAL PROFILE OF METHANOL AND AQUEOUS EXTRACTS OF Vernonia amygdalina AGAINST GASTROENTERITIS CAUSING BACTERIA." FUDMA JOURNAL OF SCIENCES 9, no. 4 (2025): 161–66. https://doi.org/10.33003/fjs-2025-0904-3564.

Full text

Abstract:

Vernonia amygdalina, commonly known as bitter leaf, is a shrub recognized for its bioactive compounds with documented antibacterial properties against gastroenteritis. However, the efficacy of methanolic and aqueous extracts of Vernonia amygdalina leaves has not been extensively evaluated. This study aimed to assess the efficacy of these extracts and determine their chemical composition, as well as their potential to inhibit the activity of selected bacteria associated with gastroenteritis. Vernonia amygdalina leaves were procured from Gombe central market, and the extracts were subjected to p

APA, Harvard, Vancouver, ISO, and other styles

29

MOHD RUSLI, NURSHAHIDAH, MOHD NORFAIZAL GHAZALLI, NORAINI TALIP, et al. "LEAF EPIDERMAL CHARACTERISTICS OF MEDICINAL Eclipta prostrata (L.) L., Vernonia amygdalina Delile (ASTERACEAE) AND Clitoria ternatea L. (FABACEAE)." Malaysian Applied Biology 50, no. 1 (2021): 189–96. http://dx.doi.org/10.55230/mabjournal.v50i1.1507.

Full text

Abstract:

A study on leaf anatomical characteristics was undertaken on three medicinal plants species, Eclipta prostrata (L.) L., Vernonia amygdalina Delile and Clitoria ternatea L. It is found that there are variables in leaf epidermal features such as anticlinal wall patterns, stomata types, trichome types, and the occurrence of secretory structures. Results showed that there is slight variation in anticlinal wall patterns, which is, sinuous on abaxial surfaces and straight to wavy on adaxial surfaces of Eclipta prostrata, straight to wavy on both abaxial and adaxial surfaces of Vernonia amygdalina, a

APA, Harvard, Vancouver, ISO, and other styles

30

Zubairu, Aminu Yakubu, Muhammad Mukhtar, Isah Saidu, et al. "Antibacterial activity of methanolic extract of bitter leaf (Vernonia amygdalina) from various component fractions using column chromatography." GSC Biological and Pharmaceutical Sciences 7, no. 2 (2019): 016–21. https://doi.org/10.5281/zenodo.4286143.

Full text

Abstract:

This research work determined the antibacterial activities of various components at different ratios from column fractions of methanolic extract of bitter leaf (<em>Vernonia amygdalina</em>), meanwhile column chromatography been the best method of separating component nowadays. The column chromatography was perform using several type of solvent such as non-polar, semi-polar, polar solvent as well as their mixture in deference ratio.  The phytochemical screening was carried out on the leaves extract of (<em>Vernonia amygdalina</em>) which revealed the presence of some active ingredients su

APA, Harvard, Vancouver, ISO, and other styles

31

Okanume, Ogochukwu Esther, Solomon Gabriel Abok, and Oluwatobi Adekunle Oso. "Leaf epidermal and petiole anatomical features as taxonomic characters in some Vernonia species in Nigeria." Bio-Research 20, no. 1 (2022): 1388–97. http://dx.doi.org/10.4314/br.v20i1.1.

Full text

Abstract:

Foliar and petiole micro-morphological characteristics of some members of the genus Vernonia namely; Vernonia amygdalina Del. (bitter variety), Vernonia amygdalina Del. (non-bitter variety), Vernonia cinerea (L) Less., Vernonia galamensis (Cass.) Less., and Vernonia adoensis Sch. Bip. in Jos, Nigeria was investigated to provide additional micro-morphological characters to support existing taxonomic information regarding the species. Epidermal peels of fresh leaves were made and transverse sections of petioles were cut using a rotary microtome. Staining was done using Safranin and slides observ

APA, Harvard, Vancouver, ISO, and other styles

32

Magaji, Auwal, Zinat Mahmud, and Aminu Mustafa. "Phytochemical Analysis and Assessment of Antibacterial Efficacy of Vernonia amygdalina (Bitter Leaf) against Some Selected Clinical Bacterial Isolates." UMYU Journal of Microbiology Research (UJMR) 8, no. 2 (2023): 174–80. http://dx.doi.org/10.47430/ujmr.2382.020.

Full text

Abstract:

Vernonia amygdalina is a plant known to contain substances with reported antimicrobial properties against various microorganisms. This study therefore, aimed at assessing the antibacterial properties of Vernonia amygdalina extract against some clinical bacterial isolates. The bacterial isolates were obtained from General hospital Azare, and the Vernonia amygdalina leaves were purchased at Azare central market. Various compounds, including saponins, glycosides, tannins, flavonoids, steroids, phenolic compounds, and alkaloids, were identified in the plant extract via phytochemical screening. Dif

APA, Harvard, Vancouver, ISO, and other styles

33

Chukwuemeka, Ibezute Albert, and Marcus-Abdul Oshone. "Exploring the Lipid-Modulating, Haematological and Antioxidant Potential of Vernonia Amygdalina and Celosia Argentea in Potassium Bromate-Induced Toxicity in Rats." International Journal of Research and Innovation in Applied Science X, no. III (2025): 466–77. https://doi.org/10.51584/ijrias.2025.10030035.

Full text

Abstract:

Background: Potassium bromate (KBrO₃) is a widely used food preservative known for its potential toxicological effects, including oxidative stress and alterations in haematological parameters. Objectives: This study aimed to investigate the lipid-modulating, haematological, and antioxidant potential of Vernonia amygdalina (bitter leaf) and Celosia argentea (shoko) in mitigating potassium bromate-induced toxicity in Wistar rats. Materials and Methods: Male and female Wistar rats (6-7 weeks old) were randomly assigned to four groups: Control (Group A), Potassium Bromate (Group B), Potassium Brom

APA, Harvard, Vancouver, ISO, and other styles

34

Hasibuan, Poppy Anjelisa Zaitun, Rasme Kita Uli Arihta Br Sitorus, Adam Hermawan, Fathul Huda, Syukur Berkat Waruwu, and Denny Satria. "Anticancer activity of the ethylacetate fraction of Vernonia amygdalina Delile towards overexpression of HER-2 breast cancer cell lines." Pharmacia 71 (June 5, 2024): 1–8. https://doi.org/10.3897/pharmacia.71.e125788.

Full text

Abstract:

<i>Vernonia amygdalina</i> Delile, coming from the Asteraceae tribe, contains active compounds that can treat breast cancer. This study examines the anticancer activity of <i>Vernonia amygdalina</i> Delile leaves, an active fraction of MCF-7/HER-2 breast cancer cells. Thin-layer chromatography determines the phytochemical screening. Cytotoxic and proliferation analyses were determined using the MTT method for the MCF-7/HER-2 breast cancer cell line. The cell cycle and apoptosis profiles were examined using flow cytometry. The results can be summarized in this study: <i>Vernonia amygdalina</i>

APA, Harvard, Vancouver, ISO, and other styles

35

Hasibuan, Poppy Anjelisa Zaitun, and Dian Fachrunisa. "Cell Cycle Inhibition and Apoptotic Induction of Vernonia amygdalina Del. Leaves Extract on MCF-7 Cell Line." Open Access Macedonian Journal of Medical Sciences 7, no. 22 (2019): 3807–10. http://dx.doi.org/10.3889/oamjms.2019.509.

Full text

Abstract:

OBJECTIVE: The research aimed to determine the cytotoxic activity, cell cycle inhibition, and apoptosis induction of the ethyl acetate extract of the African leaves Vernonia amygdalina Del. on the MCF-7 cancer cells.  METHODS: The extraction of Vernonia amygdalina Del. leaves was done using the maceration method whereas the cytotoxic was performed using MTT assay. After that, the cell cycle testing and apoptosis induction were conducted using flow cytometry assay.  RESULTS: The IC50 values of n-hexane, ethyl acetate, and ethanol extract of Vernonia amygdalina Del. on th

APA, Harvard, Vancouver, ISO, and other styles

36

Immaculate, Obika Ogochukwu, and Ochekwu Edache Bernard. "Evaluation of Iron Concentration of Five Nigerian Shrubs for their Prospective use in the Therapy of Iron Deficiency Anemia (IDA)." Journal of Nutrients 7, no. 1 (2021): 1–7. http://dx.doi.org/10.18488/journal.87.2021.71.1.7.

Full text

Abstract:

Medicinal herbs are commonly being used in the treatment of anemia traditionally and Jatropha tanjorensis Ellis & Saroja, Vernonia amygdalina Delile, Manihot esculenta Crantz, Megaskepasma erythrochlamys Lindau, Solanum macrocarpon L. are local shrubs mostly employed. This study aims to analyze the prospective use of some local shrubs in the therapy of Iron Deficiency Anemia. The proximate composition analysis and the iron content in leaves of the shrubs were determined following the methods of the association of official analytical chemists (A.O.A.C). The results obtained for iron concent

APA, Harvard, Vancouver, ISO, and other styles

37

S. I, Maryam, Abdulsalam . H, Namadina M.M, Yunusa A. Y, and Shehu S. A. "Phytochemical, Antioxidant and Antibacterial Activities of Vernonia amygdalina Del. Leaf Extract." Biological and Environmental Sciences Journal for the Tropics 21, no. 1 (2024): 1–11. http://dx.doi.org/10.4314/bestj.v21i1.1.

Full text

Abstract:

Scientific standardization as well as possible therapeutic effects of some herbal preparations, alternatives against antibiotic resistant bacterial infections indicates a strong need for conti- nuous effort to validate the use of plant materials as alternative therapy regimens with similar or higher antibiotic beneficial properties. The study was aimed to at evaluating the phytoche- mical, antioxidant, antibacterial activities of Vernonia amygdalina leaves. Phytochemical screeing was achieved using standard qualitative phytochemical screening procedures. Antibacterial studies were carried out

APA, Harvard, Vancouver, ISO, and other styles

38

Haqqi, Arini Nurul, and Wahyuni Wahyuni. "Uji EfektiviUji Efektivitas Ekstrak Etanol Kombinasi Daun Afrika (Vernonia Amygdalina Del.) dan Daun Kluwih (Artocarpus Camansi) Terhadap Penurunan Kadar Asam Urat Pada Mencit (Mus Musculus)tas Ekstrak Etanol Kombinasi Daun Afrika (Vernonia Amygdalina Del.) dan Daun Kluwih (Artocarpus Camansi) Terhadap Penurunan Kadar Asam Urat Pada Mencit (Mus Musculus)." Pharmacy Genius 2, no. 1 (2023): 1–12. http://dx.doi.org/10.56359/pharmgen.v2i1.168.

Full text

Abstract:

Pendahuluan: Penyakit asam urat atau gout merupakan salah satu kategori penyakit kronis tidak menular, yang di tandai dengan adanya hiperurisemia atau peningkatan kadar asam urat dalam darah. Tujuan: Untuk mengetahui konsentrasi berapa dari kombinasi ekstrak daun afrika (Vernonia amygdalina Del.) dan daun kluwih (Artocarpus camansi) yang efektif dalam menurunkan kadar asam urat mencit (Mus musculus). Metode: Penelitian ini merupakan eksperimental laboratorium dengan menggunakan metode RAL (Rancangan Acak Lengkap) dan selanjutnya dilakukan analisis data menggunakan uji one way ANOVA yang dibagi

APA, Harvard, Vancouver, ISO, and other styles

39

Oloruntola, Olugbenga D., Fehintoluwa S. Oladebeye., Samuel A. Adeyeye., Simeon O. Ayodele, Ojurereoluwa A. Ayodele, and Olufemi E. Adeniji. "INVESTIGATING THE BIOCHEMICAL PROFILE AND NUTRITIONAL COMPOSITION OF VERNONIA AMYGDALINA LEAVES: A STUDY ON ANTIOXIDANT PROPERTIES, PHYTOCHEMICAL COMPOSITION, ENZYME INHIBITION, AND PROTEIN ACTIVITY." Acta Scientifica Malaysia 8, no. 1 (2024): 15–20. https://doi.org/10.26480/asm.01.2024.15.20.

Full text

Abstract:

In this comprehensive study, the biochemical profile and nutritional composition of Vernonia amygdalina leaves were examined, focusing on their antioxidant properties, phytochemical composition, enzyme inhibition, and protein activity. A meticulous extraction process using 70% ethanol yielded an ethanolic extract of Vernonia amygdalina leaves powder (VLP), which exhibited substantial Vitamin C content (12.95 mg/g) and impressive antioxidant activity, as evidenced by a 2,2-diphenyl-1-picrylhydrazyl hydrate value of 60.24% and a ferric ion reducing antioxidant power value of 49.22 mg/g. The extr

APA, Harvard, Vancouver, ISO, and other styles

40

Alara, OR, NH Abdurahman, CI Ukaegbu, and OU Osazuwa. "Antibacterial Activity of Vernonia amygdalina and Vernonia cinerea Leaf Extracts through Microwave-Assisted Extraction Technique." Nigerian Research Journal of Engineering and Environmental Sciences 07, no. 02 (2022): 413–19. https://doi.org/10.5281/zenodo.7496588.

Full text

Abstract:

<em>The occurrence of multi-drug-resistant bacteria has been a great challenge facing public health care in recent times. Therefore, this study investigated the antibacterial activity of extracts from two species of Vernonia (Vernonia amygdalina and Vernonia cinerea) against Bacillus cereus, Enterococcus faecalis, Pseudomonas aeruginosa, and Escherichia coli. The results obtained showed that the tested bacteria were sensitive to extracts from both plant samples in the concentration range of 6 to 30 mg/mL. Higher sensitivities were seen at a concentration of 30 mg/mL. Moreover, the sensitivitie

APA, Harvard, Vancouver, ISO, and other styles

41

Akunna, Gabryel G., LC Saalu, A. Irozuoke, and E. Joshua. "Rats kidney morphological particularities and functions post-treatment with vernonia amygdalina extract and low-dose lead acetate." European Journal of Anatomy 27 (January 2023): 91–102. http://dx.doi.org/10.52083/ztzk6810.

Full text

Abstract:

This study was conducted to evaluate the effect of Vernonia amygdalina extract on Pb-induced kidney toxicity in Wistar rats. This investigation was carried out using 25 Wistar rat of both sexes, and the animals were divided into five groups: 5 rats per group. Group A served as the negative control group and was orally gavaged with 5mg/ kg body weight of normal saline daily. Group B served as the positive control and was treated with daily intraperitoneal (IP) injection of 8 mg/kg body weight of Pb acetate (Pb). Group C was treated with daily intraperitoneal (IP) injection of 8 mg/kg body weigh

APA, Harvard, Vancouver, ISO, and other styles

42

Mashunah, Evi, Erwin, and Saibun Sitorus. "Isolasi dan Identifikasi Steroid dari Ekstrak N-Heksana Daun Afrika (Vernonia amygdalina Del.)." KOVALEN: Jurnal Riset Kimia 6, no. 1 (2020): 18–22. http://dx.doi.org/10.22487/kovalen.2020.v6.i1.15032.

Full text

Abstract:

Isolation and identification of steroids from the n-hexane fraction of Vernonia amygdalina Del. was carried out. Separation and purification were performed using flash chromatographic and gravity chromatography. Based on the results of phytochemical tests supported by UV and FT-IR data analysis, the isolate obtained was a steroid (sterol type). Toxicity test results using the Brine Shrimp Lethality Test (BSLT) were known that the steroid has moderate toxicity with an LC50 value of 48.39 ppm. Keywords: Vernonia amygdalina Del., Toxicity, BSLT, Sterol, Steroid

APA, Harvard, Vancouver, ISO, and other styles

43

Degu, Amsalu, Belayneh Kefale, Diriba Alemayehu, and Gobezie Temesgen Tegegne. "Evaluation of the Antidiarrheal Activity of Hydromethanol Crude Extracts of Ruta chalepensis and Vernonia amygdalina in Mice." Evidence-Based Complementary and Alternative Medicine 2020 (April 13, 2020): 1–6. http://dx.doi.org/10.1155/2020/8318713.

Full text

Abstract:

Background. The herbal medicine practitioners in Ethiopia have used a wide range of medicinal plants as antidiarrheal agents. Among these, Ruta chalepensis and Vernonia amygdalina were claimed to have antidiarrheal activity in Ethiopian folklore medicine. Hence, the aim of the present study was to evaluate the antidiarrheal activity of the crude extracts of Ruta chalepensis and Vernonia amygdalina in mice. Methods. The crude extracts were obtained by cold maceration with 80% methanol, and its antidiarrheal activities were evaluated using a castor oil-induced diarrheal model. The test groups we

APA, Harvard, Vancouver, ISO, and other styles

44

Syahputra, Rony Abdi, Urip Harahap, Yahdiana Harahap та ін. "Vernonia amygdalina Ethanol Extract Protects against Doxorubicin-Induced Cardiotoxicity via TGFβ, Cytochrome c, and Apoptosis". Molecules 28, № 11 (2023): 4305. http://dx.doi.org/10.3390/molecules28114305.

Full text

Abstract:

Doxorubicin (DOX) has been extensively utilized in cancer treatment. However, DOX administration has adverse effects, such as cardiac injury. This study intends to analyze the expression of TGF, cytochrome c, and apoptosis on the cardiac histology of rats induced with doxorubicin, since the prevalence of cardiotoxicity remains an unpreventable problem due to a lack of understanding of the mechanism underlying the cardiotoxicity result. Vernonia amygdalina ethanol extract (VAEE) was produced by soaking dried Vernonia amygdalina leaves in ethanol. Rats were randomly divided into seven groups: K-

APA, Harvard, Vancouver, ISO, and other styles

45

O., Oluyele, and K.Oladunmoye M. "Susceptibility Patterns of Staphylococcus aureus Isolated from Wounds Swabs to Extracts of Vernonia amygdalina." Journal of Advances in Medical and Pharmaceutical Sciences 13, no. 4 (2017): 1–11. https://doi.org/10.9734/JAMPS/2017/33837.

Full text

Abstract:

<strong>Aims: </strong>There is an ever growing interest in investigating different groups of plants to identify their potential therapeutic applications. This is due to a tremendous historical legacy in folk medicine use of plants as remedy for treating diseases. <em>Vernonia amygdalina</em> have been shown to exhibit profound ethnomedical and pharmacological properties. The present study investigated the susceptibility patterns of <em>Staphylococcus aureus </em>isolated from wound infections to extracts of <em>Vernonia amygdalina.</em> <strong>Study Design:</strong> This study was designed t

APA, Harvard, Vancouver, ISO, and other styles

46

Agbidye, Isaac Gbaa, Timothy Tertsea Awuhe, and Susan Doofan Iortyom. "Comparative Proximate and Phytochemical Analyses of the Leaf Extracts of two Species of Vernonia." Chemistry Research Journal 5, no. 2 (2020): 185–94. https://doi.org/10.5281/zenodo.12493111.

Full text

Abstract:

<strong>Abstract </strong>Comparative proximate and phytochemical analyses of two variants of bitter leaf; <em>Vernonia </em><em>amygdalina</em> and <em>Vernonia colorata</em><em> </em>were studied using AAS, UV, IR and TLC. Extraction was done with ethanol using the powdered leaves of the two variants, distilled off, and labelled as: ethanol extract of <em>Vernonia amygdalina </em>(EEVA) and ethanol extracts of <em>Vernonia colorata </em>(EEVC). The same procedure was repeated with acetone and water to obtain: acetone extracts of <em>Vernonia amygadalina</em><em> </em>(AEVA); acetone extracts

APA, Harvard, Vancouver, ISO, and other styles

47

Ugokwe, I. N., and C. U. Ugokwe. "Comparative study on the prebiotic effects of Inulin and aqueous extract of Vernonia amygdalina on growth and intestinal morphometry of broiler chicken (Cobb strain)." Journal of Animal Science and Veterinary Medicine 7, no. 1 (2022): 17–27. http://dx.doi.org/10.31248/jasvm2022.308.

Full text

Abstract:

Antibiotic misuses aimed at improving growth performance in poultry production have resulted to widespread of antimicrobial resistance (AMR) in poultry. Recently, prebiotics are accepted as preferred alternatives. The aim of this study was to compare the prebiotic activities of a known and commercially available substance, inulin and a locally available plant, Vernonia amygdalina (bitter leaf) on growth performance and intestinal morphometry of broiler chicken. Sixty day-old broiler chicken (Cobb strain) employed in this study were acclimatized for three weeks and randomly divided into six tre

APA, Harvard, Vancouver, ISO, and other styles

48

Ambrose, Okunima, Chukwuma S. Anakwe, Ezomoh Olubunmi Olusoga, Arhoghro Marcellinus Ejovwoke, and Prohp, The Prophet. "Vernonia amygdalina, Ocimum gratissimum and Talinum triangulare Mitigates Kidney Toxicity in Male Wistar Rats Administered with Dichlorvos." SAR Journal of Medical Biochemistry 5, no. 05 (2024): 40–49. http://dx.doi.org/10.36346/sarjmb.2024.v05i05.001.

Full text

Abstract:

This study aimed to evaluate the therapeutic potentials of extracts from medicinal plants (Vernonia amygdalina, Ocimumgratissimum, Talinum triangulare) against DDVP-induced renal toxicity in Wistar rats. A total of 50 male adult rats, each weighing approximately 272g, were divided into ten groups (n=5). The groups were given normal saline (normal control), 8.0mg/kg body weight DDVP (positive control), 8.0mg/kg body weight DDVP along with 200mg/kg and 400mg/kg body weight of the plant extracts respectively, and 20mg/kg and 40mg/kg body weight of vitamin C for 28 days. DDVP significantly (P<0

APA, Harvard, Vancouver, ISO, and other styles

49

Daturara, Brigita, Bida cincin Kirana, and Christina Indriasari. "Uji Efektivitas Ekstrak Daun Afrika (Vernonia amygdalina) Terhadap Penyembuhan Luka." JUKEJ : Jurnal Kesehatan Jompa 3, no. 1 (2024): 44–52. http://dx.doi.org/10.57218/jkj.vol3.iss1.1106.

Full text

Abstract:

Penggunaan bahan alam telah banyak digunakan sebagai pilihan alternatif untuk pengobatan tradisional, termasuk untuk penyembuhan luka. Salah satunya yang sudah terbukti secara empiris untuk penyembuhan luka adalah daun afrika (Vernonia amygdalina). Senyawa aktif yang ada pada daun afrika diantaranya berupa alkaloid, tanin, steroid, saponin dan flavonoid. Tujuan penelitian yaitu untuk mengetahui efektivitas ekstrak daun afrika (Vernonia amygdalina) dalam menyembuhkan luka. Metode pengujian dilakukan menggunakan hewan uji kelinci jantan New Zealand, yang diberi perlukaan pada bagian punggung. Ke

APA, Harvard, Vancouver, ISO, and other styles

50

Asmaydo, Dhio, Iwan Sahrial Hamid, Muchammad Yunus, Kusnoto Kusnoto, Mohammad Sukmanadi, and Endang Suprihati. "The Anthelmintics Activity of Ethanol Extract of African Leaf (Vernonia amygdalina) on Mortality of Fasciola gigantica in Vitro." Journal of Parasite Science 3, no. 1 (2019): 15. http://dx.doi.org/10.20473/jops.v3i1.16426.

Full text

Abstract:

The Aims of this study is to know the anthelmintics activity of ethanol extract of african leaf (Vernonia amygdalina) on mortality of Fasciola gigantica in Vitro. Method that used in the research was a completely randomized design. There were five treatments and each treatment was done in four replications. This research used ten Fasciola gigantica in each treatment for all replications. The observation and recording of dead Fasciola gigantica was done at 2, 4, 6, 8, and 10 hours. Fasciola gigantica were declared dead if there was no movement when disturbed by anatomy tweezers and when dipped

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!