Dissertations / Theses on the topic 'Vertebraria'
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Dalpozzo, Boris <1981>. "Il trattamento delle fratture e lussazioni vertebrali nei piccoli animali." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2009. http://amsdottorato.unibo.it/1880/.
Full textVendrame, José Roberto Benites. "Ensaios mecânicos e estudo histológico da interface dos implantes vertebrais." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/17/17142/tde-29062007-142851/.
Full textSpine surgery has developed a lot in the last years because of the evolution of the fixation system. The behavior of a screw in the bone is still unknown in many ways. Because the screw is the anchor of sustentation, this work tries to find the answers involving the pedicle screw fixation. To reach this objective we developed this work based on mechanical and histological studies. Two kinds of pedicle screws were used: pedicle screw of the USIS (Ulrich) and pedicle screw of the USS system (Synthes). The pullout tests were made in wood and polyurethane. The histological study was done in lumbar vertebra of humans. In the study about the USIS screw, the follow parameters were tested: hole done with probe and hole done with drill, all of the same inner diameter of the screw. The effect of tapping and not tapping the hole done with drill was tested. In the USS screw study, the effect of the diameter pilot hole in the pullout tests and its historical analysis was seen. In the pullout tests of these screws, both kind of holes done with probes and a drill were tested. The work was divided into stages; first stage was the study of the pullout of the USIS screw; second stage was two studies, a light-microscopic one and a sweeping-electronic-microscope one of the slides of the instrumented vertebra with USIS screws; third stage was the study of the USS screws pullout comparing the relationship between the diameter of the holes and the inner diameter of the screw together with the type of hole (drill and probe); fourth stage was light-microscopic histological study of the instrumented vertebras which had had USIS screws. Results of the first stage showed that probes were more efficient than drills because the mechanical tests of pullouts from probe-made-holes showed the need of the use of a stronger force. In the second stage, a light-microscopic analysis showed that probe-made-holes had a lesser minimum diameter and a lower index of fragmentation than drill-made holes. With relation to the tapping, there was no difference between the holes. Under electronic microscope sweeping, it was seen that probes betters compact the bone around the screw. In the third stage, it was seen that when 9 the pilot orifice was greater than the screws internal diameter a significantly lower force was needed for pullout, while when the pilot orifice was smaller it did not significantly increase the force needed. It was also seen that probe-made-holes had a better anchorage than the drill-made-holes. In the fourth stage, the histological analysis of the slides done with light-microscopy showed that the smaller the diameter of the drill the smaller minimum diameter; there was no significant difference between fragmentation indexes. Conclusion: Probes are better than drills to make a pilot hole because they cause less damage to the surrounding bone and give a stronger anchorage for the screw; the smaller the instrument used to make the pilot hole, better will be the strength of the screws anchorage; the critical point which the hole must not exceed is the internal diameter of the screw. Tapping, or not, makes no difference to the anchorage.
ARAÚJO, Bruno Martins. "Fraturas e luxações vertebrais toracolombares em cães: observações clínico-cirúrgicas." Universidade Federal Rural de Pernambuco, 2013. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5290.
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Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq
Vertebral fractures and luxations (VFL) are one of the most common and severe neurological issues found in clinical practice, with an elevated risk of permanent damage to the spinal cord. Our objective was to study the characteristics and implications associated with thoracolumbar VFL in 37 dogs examined at the Veterinary Hospital of the Universidade Federal Rural de Pernambuco. Each patient had detailed history obtained, followed by clinical, neurologic and radiographic exams. The dogs were submitted to conservative or surgical treatment according to each case. The VFL were more common in intact males with access to the street. Regarding etiology, 32 dogs were involved in car accidents. Of the dogs included in this research, 14 had non-neurological issues in other systems. Radiographic exams were 100% effective in diagnosing VFL, but 42.8% of the dogs treated surgically had vertebral lesions that weren't detected radiographically. Mean time until initial neurologic exam was 35 days, and most dogs were reffered without external coaptation. There was a significant difference in recovery of the dogs when comparing a degree of dislocation of 0 – 25% and 76 – 100%. Presence of two or three severe neurological signs was associated with a poor prognosis, while lack or just one of these indicated a favorable prognosis. Deep pain perception (DPP) was present in 37.7% of the dogs. Twenty dogs received conservative treatment, 14 underwent surgery and three dogs died before treatment for the acute spinal trauma. Of the dogs with intact DPP, 100% recovered, while none of the dogs that lost DPP recovered voluntary motion (five developed spinal walk). Presence or absence of DPP is a reliable prognostic indicator. However, there was no significant difference in time for recovery of voluntary motion in dogs with intact DPP when comparing surgical versus conservative treatment. The percentage of euthanasia was less than in other reports, probably due to the greater awareness and protectiveness of owners nowadays. Of the dogs without DPP treated either surgically or conservatively, 31.25% recovered the ambulation without recovery of DPP.
Fraturas e luxações vertebrais (FLV) são uma das afecções neurológicas mais graves e comumente encontradas na prática clínica, com elevado risco de danos permanentes à medula espinal. Objetivou-se estudar as características e implicações associadas às FLV toracolombares em 37 cães atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco. Cada paciente passou por anamnese, seguida por exames clínicos, neurológico e radiográfico. Os cães foram submetidos ao tratamento conservativo ou cirúrgico de acordo com cada caso. As FLV foram mais comuns em machos não castrados com acesso a rua. Dentre a etiologia, 32 cães foram acometidos por acidente automobilístico. Dos animais da pesquisa, 14 apresentaram lesões não neurológicas em outros sistemas. Por meio do exame radiológico se diagnosticou FLV em 100% dos casos, mas nos cães submetidos ao tratamento cirúrgico, observou-se uma grande quantidade destes apresentavam lesões vertebrais não detectadas nas radiografias convencionais (42,8%). O tempo médio ate o atendimento neurológico inicial foi de 35 dias, no qual a maioria foi encaminhada sem imobilização externa. Houve diferença estatisticamente significante ao se comparar os graus de deslocamento de 0 a 25% e de 76 a 100%. A presença de dois ou três sinais neurológicos graves esteve relacionada a prognóstico desfavorável, enquanto que a ausência ou presença de apenas um destes indicou um prognóstico favorável. A percepção de dor profunda (PDP) estava presente em 37,7% dos animais. Vinte animais foram submetidos ao tratamento conservativo, 14 ao tratamento cirúrgico e três animais faleceram antes de ser realizado o tratamento do traumatismo medular agudo propriamente dito. Dos animais que mantiveram a PDP intacta, a taxa de recuperação foi de 100%, enquanto que dos animais que perderam a PDP nenhum recuperou a deambulação voluntária (cinco adquiriram caminhar espinal). O parâmetro de ausência ou presença de PDP é um confiante indicativo do prognóstico desta afecção. Apesar de que nos animais que mantiverem a PDP intacta, independente do tratamento instituído e do grau de comprometimento neurológico, não houve diferença significante nas taxas nem no tempo de recuperação da deambulação voluntária. A taxa de eutanásia foi menor que em outros trabalhos descritos na literatura, provavelmente devido a conscientização e protecionismo dos tutores nos dias atuais. Dos animais sem PDP submetidos ao tratamento conservativo ou cirúrgico, 31,25% readquiriram a capacidade de caminhar sem recuperar a PDP.
Nastasi, Valentina <1977>. "Alterazioni del metabolismo osseo e fratture vertebrali dopo trapianto di rene." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4595/.
Full textKrieger, Carla Mariza de Lima. "Efeito dos programas de ginástica e de hidroginástica nas algias vertebrais." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 1999. http://hdl.handle.net/10183/149047.
Full textNowadays, there is concem on the behalf of health scholars so as to fight degeneratives problems of the spinal column which are responsible for the back pain. They originated form incorrectly performed movements, impacts over the joints and muscular imbalance; they can, however, be improved and even prevented through the practice of exercises which are, among others, gymnastics and hidrogymnastics. The object this study was verify the effect of gymnastics and hidrogymnastics over the back pain, associated to muscular pain, of a hospital's employees. The sample was constituted of 40 subjects suffering from chronical back pain, with an average age 41,7. A experimental group (n=8) was submitted to a gymnastics program and the other group, also experimental (n=12), to a hydrogymnastics routine. These programs included aerobic exercises, of muscularresistence, of stretching and of relaxation, developed for a period of twelve weeks of treatment, with two weekly sessions, of 45 minutes each. The control group (n=20) did not receive any treatment. The effect of the programs was analysed, through the use of a questionaire to evaluate the intensity and the frequency of the back pain, two questionaire to evaluate just the intensity of the back pain and the last one was used to evaluate the degree of disconfort ofthe pain over the Daily Life Activities. The results obtained showed that there was a statistically significant difference in the intensity and frequency of the back pain, respectivelly in the cervical area (p=0,04), shoulders (p=0,01) and shoulders and arms (p=0,03), as well as in the shoulders' area (p=0,03), shoulders and arms (p=0,00) and dorsal (p=0,04) among the hydrogymnastics and the control groups. However, in the shoulders' area, the gymnastics group, in relation of control, the gymnastics group has also shown a significant difference (p=0,02). As to the degree of the interference of the back pain over Daily Life Activities, the statistically significant difference found was between the control group and the experimental group (gymnastics (p= 0,02) and hydrogymnastics (p=0,00). One concludes that there was no statistically significant difference in the intensity, frequency and degree ofintrference ofthe back pain over the Daily Life Activities between adults who were taking part in the gymnastics program and in the hydrogymnastics one, and this suggests that both programs are appropriated for the fight against backpain.
Lopes, Jaqueline Barros. "Prevalência e fatores de risco para fraturas vertebrais em idosos da comunidade." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5145/tde-09032010-184235/.
Full textPurpose: To estimate the prevalence of radiographic vertebral fracture and investigate factors associated with this condition in Brazilian communitydwelling elderly. Methods: This cross sectional study included 769 elderly subjects 65 years old and over (462 women and 307 men) living in São Paulo, Brazil. Thoracic and lumbar spine radiographs were obtained and vertebral fractures were evaluated using Genant´s semi-quantitative method. Bone mineral density (BMD) was measured by DXA and bone biochemical markers were also evaluated. Female and male subjects were analyzed independently, and each gender was divided into 2 groups, based on whether vertebral fractures were present. Results: The prevalence of vertebral fracture was 16.7% (95% CI 13.3-20.1) in women and 21.2% (95% CI 16.6-25.7) in men. Logistic regression analyses using variables that were significant in the univariate analysis, in female group showed that age (OR=1.12, 95% CI 1.06-1.18; p<0.001) and femoral neck T-score (OR=0.61, 95% CI 0.46-0.88; p=0.006) were independently factors in predicting vertebral fracture. In the male group, logistic regression analyzes demonstrated that chronic faller condition (OR=2.54 95% CI 1.1-5.9; p=0.031) and femoral neck T-score (OR=0.72, 95% CI 0.53-0.96; p=0.025) were independent parameters in predicting vertebral fractures. Conclusions: Our results suggest that radiographic vertebral fractures are common in Brazilian community-dwelling elderly and that a low femoral neck T-score was an important risk factor for this condition in both males and females. Age was also significantly correlated with the presence of vertebral fractures in women, and chronic faller was correlated with vertebral fractures in men.
ó, Fernanda Rachel Melo e. Vidigal do. "DEFORMIDADES VERTEBRAIS EM MULHERES COM OSTEOPENIA E OSTEOPOROSE EM SÃO LUÍS, MARANHÃO." Universidade Federal do Maranhão, 2007. http://tedebc.ufma.br:8080/jspui/handle/tede/1108.
Full textPurpose: To study vertebral deformities of Osteopeny/Osteoporosis among over 40 years old women, São Luís, Maranhão. To verify frequency of vertebral deformities in lumbar column. Methods: A prospective transversal study, peri-postmenopausal women period, selected by spontaneous demand, with recent bone densitometry (last 12 months) showing osteopeny/osteoporosis, at Centro de Densitometria Óssea do Maranhão, São Luís, between March and December, 2006. A questionnaire was aplicated, solicitated sacral column radiography at Centro de Diagnóstico Médico do Maranhão. Results: In 222, with 109 osteopeny and 113 osteoporosis, according with bone densitometry results. Higher osteoporosis frequency among women with more than three gestations and deliveries, postmenopausics, diabetics, users of alcoholics drinks, not user of milk and derivates, not obese and sedentary. Vertebral deformities by the lumbar-sacral column radiography, associated with osteoporosis reduced vertebral discus spaces (52%), vertebral fractures (12%), flatten vertebral bodies (8%), vertebral collapses (4%). Vertebral deformities before osteoporosis higher frequency, like osteophytes (75%), scoliosis (69%), artrosis (35%). Conclusions: White women, low escolarity and retired, more frequent. Age between 40 and 59 years old with osteopeny, over 60 years old osteoporosis. User of Sodic Alendronate for more time than a year, initiated at perimenopause, higher osteopeny frequency. Vertebral factures and vertebral collapses were the most important osteoporosis complications in lumbar-sacral column.
Objetivos: Avaliar a presença de deformidades vertebrais, na coluna lombar, em mulheres com osteopenia/osteoporose, a partir dos 40 anos, em São Luís, Maranhão. Métodos: Estudo prospectivo, transversal, mulheres climatéricas, demanda espontânea, densitometria óssea recente (últimos 12 meses), apresentando osteopenia/osteoporose, realizado no Centro de Densitometria Óssea do Maranhão, São Luís, de março a dezembro, 2006. Foi aplicado questionário, e as pacientes submetidas à radiografia de coluna lombosacra no Centro de Diagnóstico Médico do Maranhão. Resultados: A densitometria óssea revelou nas 222 mulheres, osteopenia em 109 e osteoporose em 113. Maior freqüência de osteoporose em mulheres com mais de três gestações e partos, pós-menopáusicas, diabéticas, não obesas, sedentárias, usuárias de bebida alcoólica, não usuárias de leite e derivados. Deformidades vertebrais à radiografia de coluna lombo-sacra, associadas à osteoporose: redução de espaços discais 52%, fraturas vertebrais 12%, achatamento de corpos vertebrais 8%, colapsos vertebrais 4%. Maior freqüência de deformidades vertebrais anteriores à osteoporose: osteofitos 75%, escoliose 69%, artrose 35%. Conclusões: Cor branca, baixa escolaridade, aposentadas, faixa etária de 40 a 59 anos de idade, predominando osteopenia, e acima de 60 anos, osteoporose. Alendronato de sódio por mais de 12 meses demonstrou efeito protetor contra osteoporose. Maior freqüência de deformidades vertebrais anteriores e associadas à osteoporose. Principais complicações da osteoporose na coluna lombar: fraturas e colapsos vertebrais.
Berglund, Åsa. "Havets tryffel : En sensorisk studie på olja smaksatt med tryffeltång (Vertebrata lanosa)." Thesis, Örebro universitet, Restaurang- och hotellhögskolan, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-68926.
Full textPereira, Lucas Frighetto. "Classificação semiautomática de fraturas vertebrais benignas e malignas em imagens de ressonância magnética." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17142/tde-07062017-100712/.
Full textPurpose: Vertebral compression fractures (VCFs) result in partial collapse of vertebral bodies. They usually are nontraumatic or occur with low-energy trauma in the elderly secondary to different etiologies, such as insufficiency fractures of bone fragility in osteoporosis (benign fractures) or vertebral metastasis (malignant fractures). Our study aims to detect the presence of VCFs and classify them as malignant and benign using image processing techniques and machine learning classifiers in T1-weighted magnetic resonance images (MRI). Materials and methods: We used the median sagittal planes of lumbar spine MRIs from 63 patients (38 women and 25 men) previously diagnosed with VCFs. The lumbar vertebral bodies were manually segmented and statistical features of gray levels were computed from the histogram. We also extracted texture features to analyze the gray-level distribution, and shape features to analyze the contours of the vertebral bodies. In total, 102 lumbar VCFs (53 benign and 49 malignant) and 89 normal lumbar vertebral bodies were analyzed. After run feature selection methods to the vector of features, the k-nearest-neighbor (k-NN), neural network with radial basis functions (RBF network), a naïve Bayes classifier, J48, and Support Vector Machine (SVM) were used for classification. We compared the classification obtained by these classifiers with the final diagnosis of each case, including biopsy for the malignant fractures and clinical and laboratory follow up for the benign fractures. Furthermore, three voluntary radiologists classified the same cases analyzing the same regions of interests (ROIs) used by the classifiers and a comparison between the classifiers and the radiologists was done. xxiii Results: The results obtained by the classifiers showed an area under the receiver operating characteristic curve (AUROC) of 0.984 in distinguishing between normal and fractured vertebral bodies, and AUROC of 0.930 in discriminating between benign and malignant VCFs. Conclusion: Our method reached great results in the classification of vertebral bodies without fractures, vertebral bodies with fractures due to osteoporosis and vertebral bodies with fractures due to metastatic diseases. Our results were statistically equivalent to the results of the classifications made by radiologists and they showed to be promising in diagnosis assisting of VCFs.
Ruas, Gualberto. "Identificação da presença de osteoporose e fraturas vertebrais na doença pulmonar obstrutiva crônica." Universidade Federal de São Carlos, 2010. https://repositorio.ufscar.br/handle/ufscar/5257.
Full textIntroduction: Osteoporosis is a progressive disease with a significant reduction in bone mineral density (BMD) contributes to the emergence of osteoporotic vertebral fractures, thereby directly interfering with the quality of life of patients with chronic obstructive pulmonary disease (COPD). Objectives: Detection of osteoporosis, vertebral fractures and pain intensity in the regions of the spine in men with moderate to severe COPD, but also whether there is any relationship between the variables studied and the degree of pulmonary obstruction. Methods: We studied 34 males with COPD (COPDG) and 33 healthy sedentary men (CG), through the bone densitometry and radiographs of the thoracic and lumbar spine. Results: There were no significant differences between groups in clinical trials that were within normal limits and anthropometric data. The COPDG showed lower values in the spirometric variables, BMD and T-score at lumbar spine, femoral neck and trochanter compared with the CG (p<0,05; Student t test), moreover, there was no correlation between FEV1 and BMD and T-score (Pearson correlation, p>0,05). It was found that 28 (83%) of individuals COPDG have osteoporosis, and 20 individuals (59%) presented with moderate obstruction of the lumbar spine, 0l (3%) in the femoral neck and 0l (3%) in the trochanter; 4 (12%) with severe pulmonary obstruction in the lumbar spine, 0l (3%) and femoral neck 0l (3%) in the trochanter. Twenty subjects (59%) of COPDG with moderate obstructive pulmonary disease patients with osteoporosis showed osteoporotic vertebral fractures in segments T5, T7, T9, T11, T12 and L1 grads I and II, 4 (12%) with severe obstructive pulmonary disease patients with osteoporosis at the lumbar spine osteoporotic fractures had grade III between segments T12-L4 (k=0,90;CI: 95%; with k=0,72-1,0) already in the CG 3 subjects had vertebral fractures and osteoarthritis segments T5, T6 and L1 and none had osteoporotic vertebral fractures (k=0,89; CI: 95% with k=0,72-1,0), the pain intensity of 3 individuals COPDG obstructive lung conditions who had osteoporosis and osteoporotic vertebral fractures grade III, reported presence of pain intensity "light" in the thoracolumbar region, while 21 had osteoporotic vertebral fractures and 3 asymptomatic individuals with CG not osteoporotic vertebral fractures and arthritis reported moderate pain intensity in the lumbar region. Conclusions: We conclude that individuals with moderate to severe COPD also had pulmonary involvement, decreased BMD and osteoporotic vertebral fractures, which indicates the need to adopt measures that take into account the prevention of osteoporosis in these patients and early diagnosis of this. Still, considering the entirety of the individual's needs, these must be assessed and addressed in establishing programs of physical therapy intervention to avoid future complications such as worsening or appearance of new fractures and thus promoting the improvement of functional capacity and quality of life.
Introdução: A osteoporose é uma doença progressiva com redução significativa da densidade mineral óssea(DMO) contribuindo para o surgimento de fraturas vertebrais osteoporóticas, interferindo diretamente na qualidade de vida dos portadores de doença pulmonar obstrutiva crônica(DPOC). Objetivos: Identificar a presença da osteoporose, de fraturas vertebrais e intensidade de dor nas regiões da coluna vertebral em indivíduos com DPOC moderada a grave, como também, verificar se há relação entre as variáveis estudadas com o grau de obstrução pulmonar. Métodos: Foram avaliados 34 indivíduos do sexo masculino portadores de DPOC (GDPOC) e 33 indivíduos saudáveis, sedentários e do sexo masculino (GC), por meio da densitometria óssea e radiografias da coluna torácica e lombar. Resultados: Não houve diferenças significativas inter-grupos nos exames clínicos que se encontravam dentro dos limites da normalidade e nos dados antropométricos. O GDPOC apresentou valores menores nas variáveis espirométricas, na DMO e no escore-T nas regiões da coluna lombar, colo do fêmur e trocânter quando comparado com o GC (p≤0,05;Teste t Student); além disso, não observou-se correlação entre VEF1 e DMO e escore-T (Correlação de Pearson,p>0,05). Verificou-se que 28 (83%) dos indivíduos do GDPOC possuem osteoporose, sendo que 20 indivíduos(59%) com obstrução moderada apresentaram na coluna lombar, 0l(3%) no colo do fêmur e 0l(3%) no trocânter; 4(12%) com obstrução pulmonar grave na coluna lombar, 0l(3%) colo do fêmur e 0l(3%) no trocânter. Vinte indivíduos(59%) do GDPOC com obstrução pulmonar moderada portadores de osteoporose apresentaram fraturas vertebrais osteoporóticas nos segmentos T5,T7,T9,T11,T12 e L1 de graus I e II; 4(12%) com grau de obstrução pulmonar grave portadores de osteoporose na coluna lombar apresentaram fraturas osteoporóticas grau III entre os segmentos T12-L4 (k=0,90; IC: 95% com k=0,72-1,0), já no GC 3 indivíduos apresentaram fraturas vertebrais e artrose nos segmentos T5, T6 e L1 e nenhum apresentou fraturas vertebrais osteoporóticas (k=0,89; IC: 95% com k=0,72-1,0), quanto a intensidade da dor 3 indivíduos do GDPOC com obstrução pulmonar grave que apresentaram osteoporose e fraturas vertebrais osteoporóticas de grau III, relataram presença de dor com intensidade leve na região tóraco-lombar, enquanto 21 apresentaram fraturas vertebrais osteoporóticas assintomáticas e 3 indivíduos do GC com fraturas vertebrais não osteoporóticas e artrose relataram intensidade de dor moderada na região lombar. Conclusões: Concluímos que os indivíduos com DPOC moderada a grave apresentaram além do comprometimento pulmonar, diminuição da DMO e fraturas vertebrais osteoporóticas, o que indica a necessidade de se adotar medidas que levem em conta a prevenção da osteoporose nesses pacientes e o diagnóstico precoce dessa. Ainda, considerando-se a integralidade das necessidades do indivíduo, essas devem ser avaliadas e atendidas ao se estabelecer programas de intervenção fisioterapêutica, evitando futuras complicações tais como agravamento ou surgimento de novas fraturas e promovendo assim, a melhora da capacidade funcional e da qualidade de vida.
Thelander, Linnea, and Johan Gunnarsson. "Samband mellan muskuloskeletal smärta från columna vertebralis, rörelserädsla, tilltro till egen förmåga och balans." Thesis, Uppsala universitet, Fysioterapi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-351743.
Full textBackground: Balance capacity is a complex notion. It relies upon several abilities interacting well with each other in order to be functioning. Pain, kinesiophobia and Self-Efficacy are factors that according to studies do have an impact on the individual ́s functional capacity. Although within the area of how such variables specifically affects a balance test there are still gaps of knowledge. Objective: Examine possible correlations between pain, kinesiophobia, Self-Efficacy and balance in a population of people with musculoskeletal pain from columna vertebralis. Methods: The study was one of correlating design. The study group consisted of 18 people, 9 men and 9 women with an average age of 32 years. All of them had musculoskeletal pain from columna vertebralis and were selected through a convenience sample. Self-assessed pain, kinesiophobia, Self- Efficacy were studied separately relative to measured balance. Data was collected through Numerical Rating Scale-self assesment questionaires, Tampa Scale of Kinesiophobia and Mini- BESTest, whereon Spearman's rank correlation was applied in order to analyse correlations. Results: No significant correlations were found between self-assessed pain and measured balance, self-assessed kinesiophobia and measured balance or Self-Efficacy (self-assessed balance) and measured balance. Conclusion: In the studied group no significant correlations between pain, balance and kinesiophobia could be detected.
Brocklehurst, Neil. "The early evolution of Synapsida (Vertebrata, Amniota) and the quality of their fossil record." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2015. http://dx.doi.org/10.18452/17351.
Full textSynapsids first appear in the fossil record during the late Pennsylvanian, and dominated the terrestrial realm until the end of the Palaeozoic. This thesis provides the first detailed examination of the earliest evolution of synapsids. Modifications of previously published metrics are used to assess the completeness of their specimens, and a variety of methods are employed to measure the fit of the fossil record to the phylogeny. The analysis into the completeness of pelycosaurian-grade specimens reveals a negative correlation between diversity and the Skeletal Completeness Metric, assessing the bulk of material preserved, suggesting a tendency to name many species based on poor material. The lack of correlation between the Character Completeness Metric (assessing the proportion of phylogenetic characters that can be scored) and diversity is attributed to the history of discovery in the group: the majority of pelycosaurian-grade species were named between the 1930s and 1960s, when assignments were often based on size, location and stratigraphy rather than morphological characters. The different methods of assessing diversity provide very similar results. The initial diversification of synapsids in the Late Pennsylvanian and early Cisuralian was followed by an extinction event during the Sakmarian. A second extinction event occurred across the Kungurian/Roadian boundary. The tree topology analysis found no significant increases in diversification rate occurring in pelycosaurian-grade taxa relative to their contemporaries. A broader examination of diversification patterns in Palaeozoic and Triassic amniotes reveals a possible explanation; diversification rate shifts within early amniotes tend to occur during periods of elevated extinction.
Castro, Ilton José Carrilho de. "Estudo experimental do sequenciamento das manobras para ligamentotaxia nas fraturas vertebrais do tipo explosão." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/17/17142/tde-14022007-155451/.
Full textCASTRO, I.J.C.: Experimental study of the sequence of ligamentotaxis maneuvers in vertebral canal decompression. 2006. 59f. Thesis (Master) Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 2006. Spinal fractures may project fragments of the posterior wall of the vertebral body into the vertebral canal and these bone fragments may compress the nervous structures located in the canal. Decompression of the vertebral canal can be performed by ligamentotaxis, which is an indirect method of vertebral canal decompression. The ligamentotaxis techniques involves distraction and lordosis of the fractured vertebral segment.The objective of the present study was to analyze the influence of the sequence in which these maneuvers are performed (distraction + lordosis versus lordosis + distraction) during ligamentotaxis on vertebral canal decompression. Thoracolumbar transition vertebrae of hybrid Landrace swine aged 5 months and weighing on average 102.05± 3.47 kg were used in the study.After production of a burst fracture using a device specially developed for this purpose, the vertebrae were submitted to computed tomography and ten specimens presenting fractures of the burst type were selected. The vertebral segments were fixed with an internal fixator (Synthes) to one vertebra above and one vertebra below the fractured one. The 10 models were divided into two groups of 5. The first group was submitted to lordosis followed by distraction and called (lor+dis). At the end of the sequence of maneuvers, the vertebrae of this group were submitted to a new compression with a clamp until they returned to the initial position of the fracture. These moldels with ther repositioned fractures, denoted (R:dis+lor) were again submitted to the dis+lor sequence.The second group was submitted to distraction followed by lordosis and denoted (dis+lor).Tomography was performed after each maneuver to measure the diameter of the vertebral canal. The dislocation of the fractured vertebral fragment was measured and the values obtained were compared by the Student t-test, with the level of significance set at 5%. The results of ligamentotaxis obtained in the present study showed that the percent dislocation of the fragments was higher in the sequence starting with kyphosis correction (lordosis), but statistical analysis with a level of of significance of ? 5% (p?0,05), showed that there was no difference between the sequences with a p level of ? 0,06. This result was close to level of significance adopted, suggesting that the sequence starting with kyphosis correction (lordosis) followed by distraction strongly tended to be more effective.
Damasceno, Luiz Henrique Fonseca. "Avaliação da participação dos corpos vertebrais e discos intervertebrais na composição da lordose lombar." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/17/17142/tde-16032007-190229/.
Full textThe vertebral bodies and intervertebral discs participation in lumbar lordosis and their contribution between lumbar curves of different size were studied. 350 lumbar spine radiographs of asymptomatic adults (143 men and 207 women, average age 29 years) were evaluated. Lumbosacral (L1S1) and lumbolumbar (L1L5) curves and the angular inclination of each vertebral boby and intervertebral disc were measured using a Cobb method variant. The percentile participation of each vertebral body and intervertebral disc in the lumbossacal curve was calculated. Sex and age were compared. The subjects were separated in tree subgroups, in acording to lumbosacral curve size. The compounds of lumbar curve (discs and vertebrae) were compared in these tree subgroups. The mean lumbosacral curve was ?60,9º (-33º to ?89º). L1 vertebral body was kyphotic (2,15º), L2 was neutral (-0,36º), and the other ones were progressively lordotic from L3 (-1,56º) to L5 (-9,23º). The intervertebral discs were progressively lordotic from L1-L2 (?4,99º) to L5-S1 (?15,58º). Both vertebrae and discs showed a progressive participation in cephalic-caudal direction. The participation of discs was about 80% of lumbosacral curve, and the caudal elements (L4, L5 vertebrae and L4-L5, L5-S1 discs) contributed far 65% of the curve. The older subjects presented lumbar curves larger than younger 4º average, with significant statistical difference to L2, L5 and L3-L4 measures, with older subjects presenting bigger angular values. There were statistical differences of lumbar curves, L2 and L4 measures between sexes, with females presenting bigger values. The lumbosacral curve presented average -46,9º in minor lordosis subgroup, -64,59º in intermediate lordosis sugbroup, and ?74,13º in major lordosis subgroup. The lumbolumbar curve presented average ?33,28º in minor lordosis subgroup, -45,34º in intermediate lordosis subgroup, and ?56,96º in major lordosis subgroup. The absolut values of vertebrae and discs angles were smaller in minor lordosis subgroup than in major lordosis subgroup, but the intervertebral discs participation of was bigger in minor lordosis subgroup (88%) than intermediate lordosis (81%) and major lordosis (75%) subgroups. Complementarely, the vertebrae had a bigger participation in intermediate and major lordosis subgroups. Individually, the vertebrae presented a larger participation in major lordosis subgroup, excepting L5 that presented bigger participation in minor lordosis subgroup. The discs presented larger participation in minor lordosis subgroup. That is consequence of a more kyphotic inclination of the cephalic vertebrae in minor lordosis subgroup than the other ones, causing a compensating effect, with a larger disc participation in the small curves. The intermediate and major lordosis subgroups had the cephalic vertebrae more lordotic than that of the minor lordosis subgroup. We concluded that the intervertebral discs are the main responsible for the lumbar curve angulation and that the contribution of vertebrae and discs in lumbar curves of different sizes is not equal. In spite of a gradual increase of lordotic wedging while lumbar curve increase, the cephalic vertebrae make the disc and vertebrae participation different between different magnitude lumbar curves.
Rubira, Cassia Maria Fischer. "Estudo das diferenças de calibre entre as arterias vertebrais esquerda e direita por angiografia cerebral." [s.n.], 2002. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289210.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: Estudaram-se 14 coelhos adultos da raça Norfolk inglesa, que foram submetidos à angiografia cerebral do território vértebro-basilar durante anestesia geral, com o objetivo de se comparar os calibres das artérias vertebrais. Dentre os 14 casos analisados, o calibre da artéria vertebral esquerda foi maior em 5 (36 %), o da direita foi maior em 3 (21 %) e os calibres foram considerados similares em 6 (43 %). Estes achados guardam analogia com os dados disponíveis sobre as diferenças de calibre entre as artérias vertebrais do homem
Abstract: Fourtheen normal adult Norfolk English rabbits were submitted to angiographies of the vertebral arterial blood vessels, during geral anesthesia. The objective was to compare the diameter between the left and right vertebral arteries. Among the 14 analyzed cases, the left vertebral artery was bigger in 5 (36%), the right vertebral artery was bigger in 3 (21%) and the diameter was similar in 6 (43%). This data are similar to some disponible anatomical records of the human vertebral arterial territory
Mestrado
Anatomia
Mestre em Biologia Buco-Dental
Andrade, Cristiane Thomaz de Aquino Exel. "Pacientes com metástases vertebrais submetidos à cirurgia - avaliação da qualidade de vida relacionada à saúde." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/22/22132/tde-23112015-200209/.
Full textPain and functional disability resulting from the impairment of spinal metastasis impact significantly on Quality of Life of any patient. To reduce the symptoms, two groups of treatment are possible nowadays: surgery and/or radiotherapy. The aim of this study was to evaluate the impact of spinal decompressive surgery on Health-Related Quality of Life (HRQoL) of patients affected by metastasis at some level of the spine. It is a prospective, quantitative, descriptive correlational and longitudinal study that comprises four ratings: before surgery (T0), two (T1), four (T2) and six (T3) months after surgical procedure. The researcher held individual interviews at the hospital service prior to surgery and at the ambulatory within three moments described above. The following data collection instruments were used: structured questionnaire for sociodemographic and clinical sample characteristics; Faces Pain Scale Revised (FPS-R); questionnaire of Health-Related Quality of Life (EORTC QLQ-C30). It was performed comparison the preoperative (T0) results with times T1, T2 and T3. The sample consisted of 22 patients with a mean age of 56 years without differences in prevalence related to sex, all with low education and with average monthly income of approximately one basic wage. The most prevalent primary tumors were in order of frequency: breast, prostate, lung and colorectal. The most used surgical approach was the posterior vertebral (63,6%) in which the lumbar segment (36,4%) was the most affected. In the preoperative period (T0), participants presented low score for State of Global Health/Quality of Life and for most areas of Functional Scale and Symptoms Scale. In three different times (T1, T2 and T3) compared regarding the preoperative period (T0), there was a statistically significant improvement in the performance status, presence of pain, insomnia and constipation of patients. There was no significant difference in daily activities in any of the three periods analyzed after surgery, always taking into account the preoperative phase (T0) as standard
Abrahão, Fernando Alexandre. "Estudo da influência da técnica de preparação dos pedículos vertebrais na resistência ao arrancamento dos implantes." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-12022016-154421/.
Full textAn experimental study was conducted on swme vertebrae to investigate the effect of the technique of vertebral pedicle perforation on the pullout resistance of the implants. The technique of perforation with a burr followed by tapping of the pedicular canal (technique 1) was individually compared to the remaining ones, i.e., perforation with a burr without tapping of the pedicular canal (technique 2), perforation with a Kirschner wire with tapping of the pedicular canal (technique 3), and perforation with a probe without tapping of the pedicular canal (technique 4). Three experimental groups were used according to orifice preparation. Group I was used to compare technique 1 to technique 2, with a study of the effect of tapping on the pedicular canal. Group II was used to compare technique 1 with technique 3, with a study of the effect of mode of orifice preparation using a Kirschner wire. Group III was used to compare technique 1 to technique 4, with a study of the effect of the use of a probe for orifice preparation. Comparison of the techniques of orifice preparation according to the parameters studied (maximum pullout load, stiffness, load in the proportionality limit, maximum dislocation, and dislocation in the proportionality limit) showed no statistically significant difference between the various techniques used for preparation of the orifices of the vertebral pedicle, in terms of their effect on the pullout resistance of the implants.
Berkeljon, Jeanne. "A systematic review of Amietia vertebralis (Hewitt, 1927) and Strongylopus hymenopus (Boulenger, 1920) (Anura: Pyxicephalidae) / Jeanne Berkeljon." Thesis, North-West University, 2007. http://hdl.handle.net/10394/594.
Full textThesis (M. Environmental Science)--North-West University, Potchefstroom Campus, 2008.
Farias, Francisco Alfredo Bandeira e. "Prevalencia de osteoporose, fraturas vertebrais, ingestao de calcio e deficiencia de vitamina D em mulheres pos-menopausa." Rio de Janeiro : [s.n.], 2003. http://teses.cict.fiocruz.br/pdf/bandeirafd.pdf.
Full textFronza, Fernanda Cerveira Abuana Osório. "Avaliação prospectiva de um programa de exercícios aquáticos sobre parâmetros morfométricos vertebrais em mulheres na pós menopausa." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/39/39132/tde-28052012-155126/.
Full textNormal aging is a continuous process that results in biological and psychosocial changes, unaffected by pathologies. These changes can lead to a loss in neuromuscular and skeletal order, impacting the locomotors system in the elderly. Osteoporosis is a systemic disease that progressively affects the skeleton structure where the fractures its main consequence, mainly in the spine. The gauged of these fractures can be assessed by vertebral morphometry, by using X-ray (MRX) or X-ray absorptiometry (MXA), which consider the vertebra morphology trough comparison between the heights of its contours in 6 different points. The women, especially postmenopausal, are more susceptible to fractures. The exercise prescription should not just add physical benefits, but also consider the predisposition to the rise of new injuries, such as fractures. The high-intensity exercise in the water can act as a safety feature for a population usually weakened by age. The goal of this research was the investigation if a mechanical overload caused by a program of high-intensity water exercise is safe for the spine morphology in postmenopausal women. A prospective and controlled study was made where 108 postmenopausal sedentary women were distributed in a fracture group (n = 20) and one without fracture (n = 88). The group was distributed in control (CG) (n = 44) composed by sedentary elderly and intervention (GI) (n = 64), formed by those who participated in the protocol for water exercises. All participants received oral supplementation with 500 mg calcium and 1000 IU of Vitamin D3 and were submitted to an initial assessment and 24 weeks after intervention of water exercises. Were evaluated anthropometric data, information on ethnicity, pain parameters, neuromuscular tests applied to variables and performing bone densitometry followed by morphometry to identify fractures. The findings showed that 18.51% of the women present fracture, predominantly located in the anterior thoracic spine. Were observed significant changes for strength, flexibility and a reduction of fall´s in a group with and without fracture (p <0.05). The presence of fractures was associated with age, body mass index (BMI) and bone mineral content (BMC) of the femoral trochanter (p <0.0001). The performance variables have best scores in GI than GC, even in fractured women included in this group. The protocol used was safe for postmenopausal women
Farias, Francisco Alfredo Bandeira e. "Prevalência de osteoporose, fraturas vertebrais, ingestão de cálcio e deficiência de vitamina D em mulheres pós-menopausa." reponame:Repositório Institucional da FIOCRUZ, 2003. https://www.arca.fiocruz.br/handle/icict/4511.
Full textO objetivo deste estudo foi verificar a prevalência de osteoporose, como também de deficiência de vitamina D, de baixa ingestão de cálcio, e de fraturas vertebrais, em mulheres na pós-menopausa. Estudamos 627 mulheres com idade acima de 50 anos, com média de idade foi de 63.9 ± 8.3 anos, tempo de menopausa de 16.2 ± 8.6 anos, e índice de massa corpórea de 26.6 ± 4.3 Kg/m2. A prevalência de osteoporose foi de 28.8 por cento na coluna lombar e de 18.8 por cento no colo do fêmur. A prevalência foi maior nas pacientes que apresentaram história de fraturas quando jovens. Na faixa entre 60 a 69 anos 33.2 por cento tinham osteoporose na coluna lombar e 17.4 por cento no colo do fêmur. Entre 70 e 79 anos, 38.2 por cento na coluna lombar e em 34 por cento no colo do fêmur. Das pacientes com mais de 80 anos 54.5 por cento tinham osteoporose na coluna lombar e 72.7 por cento no colo do fêmur. Em 32 por cento a ingestão de cálcio foi considerada baixa. A média de 25OH-D sérica foi de 31.2 ± 7.4 ng/ml, sendo que 24 por cento tinham níveis abaixo de 20 ng/ml, 19.7 por cento entre 20 e 25 ng/ml, e 56 por cento acima de 25 ng/ml. Trinta e sete por cento tinham fraturas, sendo que 9 por cento tinham fraturas grau I, e 10.9 por cento tinham farturas severas.Em mulheres na pós-menopausa, verificamos uma alta taxa de prevalência de osteoporose, de fraturas vertebrais assintomáticas, de deficiência de vitamina D, e de baixa ingestão de cálcio.
Salvà, Catarineu Montserrat. "Anàlisi de les plantes i de la fauna vertebrada a la vall de Furiosos (Montnegre, Serralada Litoral Catalana)." Doctoral thesis, Universitat de Barcelona, 2000. http://hdl.handle.net/10803/1943.
Full textDes d'un punt de vista metodològic, es va pretendre posar en pràctica un mètode d'estudi corològic i cartogràfic de la flora vascular i de la fauna vertebrada. També es van dissenyar diferents mètodes de mostreig per a l'obtenció de dades estadísticament comparable.
La recerca es va desenvolupar al massís del Montnegre, a la serralada Litoral Catalana. L'àrea és de 48 km², situada 41º39' de latitud nord i 2º33' de longitud est. Aquesta zona inclou tota la vall de la riera de Fuirosos i quatre valls més petites que li són veïnes. L'àrea d'estudi està situada entre tres comarques: el Vallès Oriental, la Selva i el Maresme. Els municipis on es treballa són Sant Celoni, Fogars de Tordera, Sant Iscle de Vallalta, Sant Pol i Tordera. Gairebé tota la zona és dins el Parc Natural del Montnegre i el Corredor i està protegida pel Pla Especial de Protecció (1989).
La vall de la riera de Fuirosos és una de les més característiques del vessant vallesà del Montnegre, les seves aigües tributen a la Tordera, que desemboca a la Mediterrània, entre les poblacions de Blanes i Malgrat. Aquesta riera esdevé interessant perquè gairebé porta aigua tot l'any, els mesos d'estiu queda seca menys en el curs superior. Els anys de gran sequera l'aigua es manté als embassaments i en els trams anteriors a aquest.
Fuirosos es troba en els dominis de vegetació de la sureda, de l'alzinar i de les rouredes. Però a la zona investigada també trobem plantacions de pins i d'eucaliptus que fan evident una explotació forestal més o menys intensa. La presència d'espècies espontànies mediterrànies, eurosiberianes i d'espècies indicadores de l'estat de la vall -bioindicadores- fan de la vall un punt idoni per posar en pràctica un mètode de treball biogeogràfic on s'integri la vegetació i la fauna vertebrada.
Les aportacions principals de la tesi han estat, en primer lloc, reconèixer quins són els factors físics i humans que intervenen en la distribució de la vegetació i de la fauna. En segon lloc, l'elaboració d'un catàleg de flora i de fauna de la vall de Fuirosos: sobretot a partir d'un treball de camp sistemàtic. En tercer lloc, s'aporta la cartografia corològica de les plantes vasculars i de la fauna vertebrada més significativa, amb base UTM d'1 km de costat.
S'ha demostrat que són els quadrats UTM de la carena del Montnegre, on el relleu presenta les seves màximes pendents, on es donen els nivells més baixos de biodiversitat i de riquesa. A la carena dominen les rouredes i les castanyedes, ambdós boscos caducifolis afavorits i la majoria aprofitats per l'home, per treure la fusta. En general han estat els quadrats per on circula la riera de Fuirosos i la Tordera els que donen un valors més elevats de riquesa i de diversitat i si tenim en compte que és on hi ha els camps de conreus més grans, també és on es dóna més abundància d'espècies de fauna vertebrada.
. The main aim of the thesis is focused in the biodiversity and the species richness and in the relationship between fauna, vegetation and man in the Fuirosos valley.
The research was undertaken in the Montnegre massif, in the Coastal Catalan Ranges in Barcelona province, Spain. The study area is 48 km², located at 41º39' North and 2º33' East. Almost the entire zone is included inside the Natural Reserve of the Montnegre and Corredor and it is protected by the Special Plan of Protection (1989).
The Fuirosos valley is one of the most typical in the "vallesan" area of the Montnegre massif. Its waters drain to the Tordera, which ends at the Mediterranean Sea, between the locations of Blanes and Malgrat. Fuirosos is under the vegetation domains of the cork oaks, evergreen oaks and oaks. However, in the study area there also exist pine and eucalyptuses plantations that make evident more or less intense forest exploitation.
The main thesis contributions have been, in first place, to recognize which are the physical and human factors that intervene in the vegetation and fauna distribution. Secondly, the elaboration of a flora and fauna catalogue of the Fuirosos valley: basically obtained from a systematic fieldwork. Thirdly, the chorological cartography of vascular plants and vertebrated fauna most significant, using a 1 km side UTM grid.
It has been demonstrated that in the UTM cells that belong to the highest area of the Montnegre, the lowest levels of biodiversity and wealth of flora are found. In this area oaks and the chestnut-trees are dominant, and both are favored non-perennial forests from which man has taken advantage in order to extract wood. In general, they belong to the cells where the Fuirosos River and the Tordera River flow through, which provide higher values of wealth and of flower diversity. Bearing in mind that it is in this area where the largest agricultural fields are found, it is also the cells where the major abundance of vertebrate fauna species are found.
Depintor, Jidiene Dylese Presecatan. "Prevalência de algias vertebrais crônicas e identificação de fatores associados em uma população da cidade de São Paulo." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5137/tde-11052015-132318/.
Full textIntroduction: Spinal pain is associated with significant economic and societal impact and is an important health issue. It has recently been listed as the first cause of -years lived with disability worldwide and one of the most common reasons for which people seek medical care. Estimates of lifetime prevalence of spinal pain vary between 54% and 80%. Objectives: To estimate the prevalence of chronic spinal pain (CSP) and to identify associated factors in a sample of persons aged 15 or older from a segment of the population of Sao Paulo City, Brazil. Methods: A cross-sectional epidemiologic survey was performed to determine the prevalence of chronic spinal pain and to identify associated factors in a random sample of persons 15 years or older from a segment of the population of São Paulo City, Brazil. Face-to-face interviews were performed with 826 individuals between December 2011 and February 2012. Participants responded the following instruments: Hospital Anxiety and Depression Scale, EuroQol 5D, Alcohol Use Disorders Identification Test (AUDIT), Fargerström Test for Nicotine Dependence (FTND), and Brazil Economic Classification Criteria (CCEB). Results: A prevalence of 22% (95% CI, 19.3 - 25.0) was observed for chronic spinal pain. The following factors were independently associated with chronic spinal pain: female gender, 30 years of age or older, four or less years of formal education, symptoms consistent with anxiety and intense physical strain for the main occupation. Quality of life and self-rated health were significantly worse among CSP individuals. Conclusions: This study found a prevalence of 22% for chronic spinal pain in a segment of the population of São Paulo city. Demographic, socioeconomic, psychological and physical factors were independently associated with this condition. Quality of life and self-rated health were significantly worse among CSP individuals
Salas-Gismondi, Rodolfo. "Evolution of Neotropical biodiversity : phylogeny, ecology, and biogeography of Mesoeucrocodylia (Vertebrata Crocodyliformes) from the Miocene of Peruvian Amazonia." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS124/document.
Full textUnder the influential role of the Andean range, western Amazonia developed distinctive environmental conditions that ultimately led to divergent, higher biodiversity within the Neotropics. Although this intimate geologic-biotic interaction might have produced similar phenomena in the past, our knowledge about the tropical biotic evolution occurring in close proximity to these rapid growing mountains is poorly documented in the deep time. A pivotal time interval for the emergence of the modern Amazonian ecosystems occurred during the Miocene, when major Andean uplift remodeled the landscape of the foreland basin and fostered the onset of the Amazon River System, at about 10.5 million years ago. Proto-Amazonian biotas just prior to this episode are integral to understanding origins of Neotropical biodiversity, yet vertebrate fossil evidence was extraordinarily rare thus far. By studying the evolution, ecology, and biogeography of fossil mesoeucrocodylians (caimans, gharials, and sebecids) documented in new rich paleontological sites of eastern Peru, this research provides a snapshot of the florishing Miocene life of western proto-Amazonia. The crocodylian assemblage of the Iquitos bonebeds (middle-late Miocene transition) is extraordinary in representing both the highest taxonomic diversity (with up to seven associated species) and the widest range of snout morphotypes ever recorded in any crocodyliform community, recent or extinct. The heterogeneity of snout shapes at the Peruvian Miocene localities covers most of the morphospace range known for the entire crocodyliform clade reflecting the combined influences of long-term evolution, resource abundance and variety, and niche partitioning in a complex ecosystem, with no recent equivalent. Besides the large-bodied Purussaurus and Mourasuchus, all other crocodylians in Iquitos are new taxa, including a stem caiman—Gnatusuchus pebasensis—bearing a massive shovel-shaped mandible, procumbent anterior and globular posterior teeth, and a mammal-like diastema. This unusual species is an extreme exemplar of a radiation of small caimans with crushing dentitions recording peculiar feeding strategies correlated with a peak in proto-Amazonian molluscan diversity and abundance, deep in the so-called Pebas Mega-Wetland System. The sole long-snouted crocodylian in this community is the basalmost gavialoid of the Amazonian basin, a critical taxon that offers evidence for accurately reconstructing the ancestral anatomy and ecology of this clade. Including this new species in phylogenetic-morphometric analyses suggests that the evolution of the similar rostral pattern between South American and Indian gavialoids results from parallel evolution in riverine habitats. As part of the same prevailing Pebas biome, Fitzcarrald localities correspond to coeval paleoenvironments closer to the Andean influence (13-12 Ma). This fauna includes deep-snouted sebecids (Sebecosuchia) and advanced gavialoids (Gavialoidea) with protruding eyes, associated with a wide array of caimans (Mourasuchus, Purussaurus, Paleosuchus et Eocaiman), and further suggesting the presence of terrestrial settings and fluvially-dominated ecosystems. On the other hand, the highly endemic Iquitos faunas evolved within the dysoxic marshes and swamps typical of the long-lived Pebas Mega-Wetland System (early–early late Miocene) and declined with the inception of the transcontinental Amazon drainage, favoring diversification of longirostrine crocodylians and more modern generalist-feeding caimans. Indeed, the end of the Pebas Mega-Wetland System notably resulted in the reduction of the phylogenetic and morphotypical mesoeucrocodylian proto-Amazonian diversity, designating the beginning of the modern Amazonian faunas. The rise and demise of distinctive, highly productive aquatic ecosystems substantially influenced evolution of Amazonian biodiversity hotspots of crocodylians and other organisms throughout the Neogene
Münster, Thomas von. "Der Einfluss der Körperposition auf die zerebrale venöse Drainage eine duplexsonographische Untersuchung der Vena jugularis interna und Vena vertebralis /." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=966137590.
Full textSantos, Iranilson Medeiros Germano dos. "Influência do grau de especialização médica no diagnóstico de fraturas vertebrais benignas e malignas nas imagens de ressonância magnética." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17158/tde-17042018-154321/.
Full textBenign osteoporotic and malignant spinal fractures represent a diagnostic challenge for medical specialists. Osteoporotic benign fractures occur because of the bone fragility of osteoporosis and malignant fractures are secondary to neoplastic infiltration. These two groups have in common the fact that they affect predominantly the elderly population. Some radiological signs favor the diagnosis of benign osteoporotic fractures while other imaging signs favor the diagnosis of malignant fractures, however no signs identified in the images are specific. The purpose of this study was to identify whether the level of medical training of radiologists and orthopedists (spine surgeons) influences the etiological diagnosis of these fractures in lumbar spinal MRI (magnetic resonance imaging), as well as to evaluate the degree of intra and interobserver agreement for the diagnosis of benign fractures due to osteoporosis and malignant fractures. We retrospectively included the exams of 63 consecutive patients from the clinical routine of the HCRP, performed previously by clinical indication and with diagnosis of non-traumatic vertebral body fracture. To evaluate the influence of the level of medical training, four radiologists and two spine surgeons with different levels of training performed evaluations independently, without knowing the other readings and without the information in the medical record. The anonymized MRI in the DICOM format were evaluated in OsiriX workstation. Observer doctors did the readings by classifying each vertebra in the lumbar region as follows: no fracture, with fracture of benign features or with fracture of malignant characteristics. Each observer performed two readings, with a 15-day interval between readings. The reference standard was obtained from the detailed evaluation of each patient\'s electronic medical record by a senior radiologist, with the Hospital Information System (HIS) and the Computerized Radiology System, including biopsy with histopathological confirmation in cases of neoplasia and clinical and laboratory follow-up for at least two years in cases in which there was no clinical indication of biopsy. Using this reference standard, sensitivity, specificity, accuracy, positive and negative predictive value with 95% confidence interval (CI) were calculated for each reading. The results demonstrate excellent intraobserver agreement and good interobserver agreement, but without statistical relevance. In addition, the sensitivity of the observers for the detection of malignant fractures was generally good. The specificity, accuracy and negative predictive value were high for all observers. The positive predictive value ranged from moderate to substantial. Therefore, there was no influence of the level of medical training for diagnostic performance in the detection of benign osteoporotic fractures and malignant fractures in magnetic resonance imaging.
Pernegre, Vincent. "Les ptéraspidiformes (vertebrata, heterostraci) de la formation de Wood Bay (Dévonien inférieur, Spitsberg) : position phylogénétique, implications biostratigraphiques et paléobiogéographiques." Paris, Muséum national d'histoire naturelle, 2004. http://www.theses.fr/2004MNHN0018.
Full textThe Pteraspidiformes of the Wood Bay Formation reveals an high diversity. Doryaspis is composed of 6 species ; Gigantaspis 4 species; Xylaspis and Woodfjordaspis nov. Gen. Are monospecifics. New faunal assemblages are proposed. They are correlated to the faunal divisions of the biostratigraphic scale of the formation. The lithostratigraphic scale is caracterised too and compared with the preceding one. The Austfjorden member is equivalent to the Sigurdfjellet-Kapp Kjeldsen divisions, and the Dicksonfjord Member as equivalent to the Keltiefjellet division. Comparisons with the Russian Arctic allow to consider the Spokojnaya Formation (Severnaya Zemlya), the Mount Veselye Formation (Novaya Zemlya) and the Sigurdfjellet-Kapp Kjeldsen divisions (Svalbard) as equivalent. This proposition is completed by new sub-province named: Gigantaspis sub-Province. The cladistic analysis leads to a revision of the admitted classification, and does not support the monophyly of the "Protopteraspididae"; yet it confirms that of the Pteraspididae and Protaspididae. The Gigantaspididae nov. Fam. Is proposed as the sister-group of the Protaspididae
Goulart, Gladstone. "O valor dos critérios de indicação da angiotomografia no diagnóstico de lesões das artérias carótidas e vertebrais no trauma contuso." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-12012011-180454/.
Full textBackground: Blunt trauma of the carotid and vertebral arteries (LCCV) are infrequent, but may have serious repercussions. The incidence of this type of injury is difficult to evaluate as many patients are neurologically asymptomatic when assisted in emergency rooms, or with symptoms attributed to cranium trauma or to other associated injuries. Recent statistical data show an incidence of 0.24% to 0.33% traumatized patients that carry some neurological symptom, we are not aware of any papers in Brazil that have studied the occurrence of LCCV. On the other hand, the real morbidity and mortality are not clearly determined, not even in the international literature. The objectives of the current study were: a) to evaluate the incidence of carotid and vertebral artery injuries in 100 patients with blunt trauma subjected to cervical angiography, using parameters obtained from the initial clinical evaluation and tomography of the patients and b) to verify which criteria for recommending cervical angiography are most related to the presence of LCCV in the trauma services section in a Brazilian quaternary care hospital. Method: During thirty months, starting in July 2006, all patients admitted in the emergency room of Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, with blunt cervical trauma, with potential risk of injuries to cervical vessels that presented neurological deficit unexplained after cranial CT scan, cerebral infarction, stable cervical haematomas, severe epistaxis, anisocoria/sign of Horner`s syndrome, Glasgow coma scores bellow 8 that are not explained by CT scan, cervical spine fracture, basilar skull fracture, facial fracture (Le Forte II or III), seatbelt signals above the clavicle, cervical hum or bruit were included in the study. The patients were subjected to cervical angiography in order to diagnose LCCV. There were analyzed the mechanisms of injuries, gender, age, severity of LCCV, type of treatment and outcome. The patients were divided into two groups: without LCCV (Group I) and with LCCV (Group II). The data analyzed are presented as mean minus standard deviation and the statistical analyzes were done using Chi-square and Fisher`s exact tests, and the Mann-Whitney test. For date comparison, a p-value <=0,05 was considered significant. Results: 2.467 patients, victims of blunt trauma, were included in the study. In 100 patients that presented the criteria for the inclusion in the study, the angiography identified 23 with LCCV, 17 male and 6 female. The mean age was 34,81±14,84 years. Car crash (49%) and car-pedestrian accidents (24%) were the most frequent mechanisms of injury, followed by falling from altitude (18%), and other mechanisms (9%). Ten patients suffered internal carotid artery injury, 2 patients with common carotid artery injury, and eleven patients with vertebral artery injury. Seven patients presented arterial injury level I, 10 level II, 4 level IV and 1 level V and one carotid fistula. Seven (30,4%) out of the 23 patients with LCCV presented cervical vertebrae fractures and 11 (47,8%) presented facial fracture (LeFort II e III). Seventeen patients were treated clinically and six underwent endovascular treatment (one stent and five embolizations). Conclusion: The criteria used in this study have allowed the diagnosis of LCCV in 0,93% of the cases, those being such injuries that occurred in the most seriously traumatized patients, and did not lead to death in the studied population.
Zeisberger, Marcel Philippe [Verfasser]. "Interventionelle Behandlungen von Stenosen der Arteria vertebralis : Eine retrospektive Studie zu kurz- und langfristigen Ergebnissen der Stent- und Ballonangioplastie / Marcel Philippe Zeisberger." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2020. http://d-nb.info/1218530235/34.
Full textCavalcante, Jeancarlo Fernandes. "Efeitos da simpaticotomia endosc?pica sobre as art?rias car?ticas e vertebrais na terap?utica cir?rgica da hiperidrose prim?ria." Universidade Federal do Rio Grande do Norte, 2005. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13366.
Full textAnalyze, in patients with primary hyperhidrosis (PH) who was undergone to videothoracoscopic sympathicotomy, the degree of vascular denervation after surgical transection of the thoracic sympathetic chain by measuring ultrasonografic parameters in carotid and vertebral arteries. Methods: Twenty-four patients with PH underwent forty-eight endoscopic thoracic sympathicotomy and were evaluated by duplex eco-doppler measuring systolic peak velocity (SPV), diastolic peak velocity (DPV), pulsatility index (PI) and resistivity index (RI) in bilateral common, internal and external carotids, besides bilateral vertebral arteries. The exams were performed before operations and a month later. Wilcoxon test was used to analyse the differences between the variables before and after the sympatholisis. Results: T3 sympathicotomy segment was the most frequent transection done (95,83%), as only ablation (25%) or in association with T4 (62,50%) or with T2 (8,33%). It was observed increase in RI and PI of the common carotid artery ( p<0,05). The DPV of internal carotid artery decreased in both sides (p<0,05). The SPV and the DPV of the right and left vertebral arteries also increased (p<0,05). Asymmetric findings were observed so that, arteries of the right side were the most frequently affected. Conclusions: Hemodynamic changes in vertebral and carotid arteries were observed after sympathicotomy for PH. SPV was the most often altered parameter, mostly in the right side arteries, meaning significant asymmetric changes in carotid and vertebral vessels. Therefore, the research findings deserve further investigations to observe if they have clinical inferences
O delineamento desse estudo objetiva a an?lise das repercuss?es na hemodin?mica das art?rias car?tidas e vertebrais, respons?veis pela irriga??o do enc?falo, ap?s a desnerva??o da cadeia simp?tica ao n?vel de T2, T3 e/ou T4, provocada pela simpaticotomia tor?cica videotoracosc?pica para tratamento da hiperidrose prim?ria. Foram estudados pacientes submetidos a 48 simpaticotomias tor?cicas por v?deo, utilizando como par?metros de compara??o pr? e p?s-operat?rios vari?veis num?ricas de velocidade de pico sist?lico, velocidade de pico diast?lico, ?ndice de resist?ncia e ?ndice de pulsatibilidade. As vari?veis foram obtidas a partir do exame de eco-doppler das art?rias car?tidas e vertebrais bilateralmente utilizando o mesmo aparelho de ultrassom e o mesmo examinador no per?odo de uma semana que antecedeu ao procedimento cir?rgico e 30 dias depois da opera??o. As diferen?as das vari?veis do pr? e do p?s-operat?rio foram mensuradas pelo teste de Wilcoxon, utilizando o software SPSS? 7.5 for Windows (SPSS, Inc., Chicago, IL). Os achados de altera??es significativas foram discutidos, observando os dados da literatura m?dica relacionados com estudos na mesma linha de investiga??o e enfatizando os aspectos de interdisciplinaridade cient?fica
Brocklehurst, Neil [Verfasser], Jörg [Akademischer Betreuer] Fröbisch, Johannes [Akademischer Betreuer] Müller, and Kenneth [Akademischer Betreuer] Angielczyk. "The early evolution of Synapsida (Vertebrata, Amniota) and the quality of their fossil record / Neil Brocklehurst. Gutachter: Jörg Fröbisch ; Johannes Müller ; Kenneth Angielczyk." Berlin : Lebenswissenschaftliche Fakultät, 2015. http://d-nb.info/1078949565/34.
Full textDemangel, Miranda Diego B. "Clasificación de humedales en la cuenca del Río Copiapó para la conservación de la fauna vertebrada, según su valor ambiental y la presión antrópica." Tesis, Universidad de Chile, 2011. http://www.repositorio.uchile.cl/handle/2250/112789.
Full textLos humedales de la cuenca del río Copiapó se encuentran en una situación crítica debido a la intervención y la extracción de agua para actividades humanas. Se realizó una clasificación de 30 humedales en base a su relevancia ambiental para la conservación, la cual se obtuvo a partir de la ponderación del valor ambiental, definido como la combinación de algunos atributos comunitarios de la fauna vertebrada (riqueza de especies, singularidad, especies amenazadas), y de la presión antrópica (una medida de la intervención humana actual y potencial) a partir de cartografías de usos del territorio. Además, se analizaron y compararon tres ecuaciones de valor ambiental propuestas. Los resultados mostraron las dificultades en el levantamiento de información y la importancia de los algoritmos elegidos para la valoración de sitios. Se destaca lo inevitable de establecer criterios subjetivos de priorización o, en su defecto, utilizar objetivos de conservación predeterminados. Por medio de las ecuaciones propuestas se determinó la presencia de tres sitios de alta relevancia ambiental: el Estuario del Río Copiapó (ya se encuentra dentro de un área de protección oficial); Río Manflas (se encuentra próximo a un sitio prioritario para la conservación, que corresponde a una declaración de intenciones por organismos públicos); y Piedra Colgada (se encuentra ubicado en una zona de alta presión antrópica y denota deterioro ambiental). Se recomienda la protección oficial de los dos últimos sitios mencionados y medidas de restauración del cause asociado al sector de Piedra Colgada.
The wetlands of the Copiapó River basin are in critical condition as a result of human intervention and water extraction. A total of 30 sites wetlands were classified based on the environmental relevance for conservation, which was obtained from the combination of the environmental value, defined as the combination of some community attributes of the vertebrate fauna (species richness, singularities, threatened species), and the anthropogenic pressure, a measure of the actual and potential human intervention in the territory. Three equations of environmental value are proposed and discussed, which showed the difficulties of data collection and the choice of algorithms, where stands out the inevitability of using subjective criteria or establishing objectives for conservation. Using the three proposed equations, 3 sites were defined as of high environmental relevance: the Estuary of the Copiapó river is already inside an officially protected area; Manflas river is near to a site of priority for the conservation, that corresponds to a statement of purpose for public organisms; Piedra Colgada is in an area of “high” anthropogenic pressure. It is recommended the protection of the last two mentioned sites and restoration measures in the riverbed associated to the Piedra Colgada zone.
Merzou, Fatma [Verfasser], and Wolfgang [Akademischer Betreuer] Reith. "Interventionelle Therapie von Stenosen der extracraniellen und intracraniellen Abschnitte der Arteria vertebralis mit technischer Erfolgs- und Komplikationsrate und 30 Tage follow-up / Fatma Merzou ; Betreuer: Wolfgang Reith." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2018. http://d-nb.info/1165574012/34.
Full textMachado, Luana Gerheim. "Gordura visceral medida por DXA está associada com risco aumentado de fraturas não vertebrais em mulheres idosas não obesas: São Paulo Ageing e Health (SPAH) Study." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-15122017-120924/.
Full textIntroduction: The protective effect of obesity on bone health has been questioned because visceral fat has been demonstrated to have a deleterious effect on bone. However, to date, there have been no studies evaluating the association between visceral fat measured by dual-energy Xray absorptiometry (DXA) with fracture risk. Objective: The aim of this study was to investigate the association of visceral fat measured by DXA with the incidence of non-spine fractures in community-dwelling elderly women. Methods: This longitudinal prospective population-based cohort study evaluated 433 community-dwelling women aged 65 years or older. A clinical questionnaire, including personal history of a fragility fracture in non-spine osteoporotic sites, was administered at baseline and after an average of 4.3 years. All incidences of fragility fractures during the study period were confirmed by affected-site radiography. Visceral adipose tissue (VAT) was measured in the android region of a whole-body DXA scan through a specific software. Logistic regression models were used to estimate the relationship between visceral fat and non-spine fractures. Results: The mean age was 72.8 ± 4.7 years, and 28 incident non-spine osteoporotic fractures were identified after a mean follow-up time of 4.3 ± 0.8 years. According to the Lipschitz classification for nutritional status in the elderly, 38.6% of women were nonobese (BMI <= 27 kg/m²) and 61.4 % were obese/overweight (BMI > 27 kg/m²). After adjusting for age, race, previous fractures, and bone mineral density (BMD), VAT (mass, area, volume) had a significant association with the incidence of non-spine fractures only in nonobese elderly women (VAT mass: OR 1.42, 95 % CI 1.09-1.85, p = 0.010; VAT area: OR 1.19, 95 % CI 1.05-1.36, p = 0.008; VAT volume: OR 1.40, 95 % CI 1.09-1.80, p = 0.009). Conclusion: This study suggests a potential negative effect of visceral adiposity on bone health in nonobese women
Vézina, Daniel. "Plourdosteus canadensis (woodward 1892), un arthrodire du frasnien inferieur du canada : contribution a l'etude morphologique et phylogenetique des plourdosteidae (vertebrata, placodermi) du devonien moyen et superieur." Paris 7, 1988. http://www.theses.fr/1988PA077165.
Full textLignereux, Yves. "Atlas stéréotaxique de l'encéphale de la vache frisonne (Bos Taurus L. )." Toulouse 3, 1986. http://www.theses.fr/1986TOU30147.
Full textBastians, Philipp [Verfasser], Matthias [Gutachter] Wiese, and Roland Ernst [Gutachter] Willburger. "Die Bedeutung der Crista vertebralis mediana posterior (Crista Krämer) als eine die Mittellinienmembran unterstützende Struktur für die Operation des lumbalen Bandscheibenprolaps / Philipp Bastians ; Gutachter: Matthias Wiese, Roland Ernst Willburger ; Medizinische Fakultät." Bochum : Ruhr-Universität Bochum, 2015. http://d-nb.info/1148750509/34.
Full textRaschke, David [Verfasser], Marios-Nikos [Akademischer Betreuer] Psychogios, Michael [Akademischer Betreuer] Knauth, and Hans-Christoph [Akademischer Betreuer] Ludwig. "Halsgefäßstenosen: Computertomographische Angiographie (CTA) versus Digitale Subtraktionsangiographie (DSA) : Eine Validitätsstudie zur Stenoseermittlung in der Arteria carotis und Arteria vertebralis / David Raschke. Gutachter: Michael Knauth ; Hans-Christoph Ludwig. Betreuer: Marios-Nikos Psychogios." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044768088/34.
Full textBastians, Philipp [Verfasser], Matthias Gutachter] Wiese, and Roland Ernst [Gutachter] [Willburger. "Die Bedeutung der Crista vertebralis mediana posterior (Crista Krämer) als eine die Mittellinienmembran unterstützende Struktur für die Operation des lumbalen Bandscheibenprolaps / Philipp Bastians ; Gutachter: Matthias Wiese, Roland Ernst Willburger ; Medizinische Fakultät." Bochum : Ruhr-Universität Bochum, 2015. http://d-nb.info/1148750509/34.
Full textQuentel, Claire. "Modifications sanguines consécutives à l'inoculation d'agents phlogogènes chez la truite arc-en-ciel (salmo gairdneri richardson) cathéterisée." Brest, 1988. http://www.theses.fr/1988BRES2023.
Full textCaldani, Martine. "Mise en évidence immunohistochimie des neurones à LHRH du mouton (ovies aries) : systématisation et ontogenèse." Paris 6, 1986. http://www.theses.fr/1986PA066483.
Full textDomiciano, Diogo Souza. "Incidência e fatores de risco para fratura vertebral por osteoporose em idosos brasileiros da comunidade: um estudo prospectivo de base populacional. São Paulo Ageing e Health (SPAH) Study." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5166/tde-11052015-161753/.
Full textVertebral fractures are associated with increased future fracture risk and mortality. No data on incidence of osteoporotic vertebral fracture have been reported in low-income countries where the population\'s aging has been faster. Thus, we sought to describe the incidence and risk factors for radiographic vertebral fracture in a longitudinal prospective Brazilian population-based elderly cohort. 707 older adults (449 women and 258 men) were evaluated with spinal radiographs obtained at baseline and after a mean follow-up of 4.3 ± 0.8 years. New vertebral fracture was defined as distinct alteration in the morphology of vertebrae resulting in higher grade of deformity on the second radiograph when compared to the baseline radiograph. Clinical questionnaire, bone mineral density (BMD), and laboratory tests were performed at baseline. Multivariate Poisson regression models were used to identify independent predictors of fracture. The age-standardized incidence of vertebral fracture was 40.3/1,000 person-years in women and 30.6/1,000 in men. In women, three models of risk factors for fracture were fitted: (1) age (relative risks (RR) 2.46, 95 % confidence interval (CI) 1.66-3.65), previous osteoporotic fracture (RR 1.65, 95 % CI 1.00-2.71), and lumbar spine BMD (RR 1.21, 95 % CI 1.03-1.41); (2) age (RR 2.25, 95 % CI 1.52-3.34) and femoral neck BMD (RR 1.42, 95 % CI 1.11-1.81); (3) age (RR 2.11, 95 % CI 1.41-3.15) and total hip BMD (RR 1.56, 95 % CI 1.21-2.0). In men, the highest quartile of cross-linked C-telopeptide (CTx) (RR 1.96, 95 % CI 0.98-3.91) and prior fracture (RR 2.10, 95 % CI 1.00-4.39) were predictors of new vertebral fracture. This is the first population-based study to ascertain the incidence of vertebral fracture in elderly Latin Americans, confirming the high frequency of the disorder. Age, prior fracture, BMD, and bone turnover were predictors of the short-term incidence of vertebral fracture
LEGRAND, PHILIPPE. "Biosynthese et utilisation des lipides chez le poulet (gallus domesticus) : comparaison de deux lignees selectionnees de poulets maigres et gras." Paris 6, 1987. http://www.theses.fr/1987PA066480.
Full textMartineau, Thuillier Stephanie. "Rôle du disque télophasique dans la dynamique de la cytokinèse : étude de la régulation et des fonctions de la protéine TD-60." Université Joseph Fourier (Grenoble ; 1971-2015), 1998. http://www.theses.fr/1998GRE10078.
Full textOliveira, Rogerio Jorge Barbosa de. "Incorporação e esterificação do colesterol na lipoproteína de alta densidade (HDL): avaliação de biomarcadores plasmáticos e do diagnóstico por imagem (ecografia vascular com doppler) relacionados com a doença aterogênica de carótidas extracranianas e artérias vertebrais." reponame:Repositório Institucional da FIOCRUZ, 2012. https://www.arca.fiocruz.br/handle/icict/4270.
Full textMade available in DSpace on 2012-08-03T19:33:51Z (GMT). No. of bitstreams: 1 Rogerio Jorge Barbosa Oliveira Incorporação e esterificação do colesterol na... 2012.pdf: 2467697 bytes, checksum: 40447b73cfb90f7a212555b74a8d0091 (MD5) Previous issue date: 2012
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
As complicações da aterosclerose agregam as principais causas de morte no mundo relacionada a problemas cardiovasculares. É caracterizada por distúrbio da condição mecânica e fisiológica, que promove espessamento e endurecimento nas ar tér i as coronárias, cerebrais e periféricos, ocasionando lesão inflamatória crônica, rica em lipídios e células características do processo inflamatório nas paredes vasculares. Objetivos: Avaliar concentrações plasmáticas de biomarcadores do metabolismo lipídico e resultados de doppler de carótidas, relacionando-os com a doença aterogênica de carótidas. Delineamento: Estudo de Corte Transverso. Casuística e Métodos: 66 pacientes com idade 57,5 ± 15,5 anos, (20 a 77), 63% mulheres. Na análise estatística utilizaram-se testes paramétricos e nãoparamétricos, valores de p < 0,05 foram considerados estatisticamente significantes. Resultados: Verificou-se DCA na população masculina a partir da faixa 36-45 anos; nas mulheres, a doença pôde ser detectada a partir de 46-55 anos, elevando-se em ambos gêneros conforme aumento da idade. Tivemos maior prevalência de DCA no gênero feminino (33% contra apenas 15%), na faixa de 56-65 anos, mostrando RR de 1,56 para o gênero feminino (p<0,002; teste de Fisher, com aproximação de Katz). Quanto ao perfil clínico, houve prevalência de 53% pacientes com DCA; 82% pacientes estavam em uso de medicação regular para quaisquer das doenças pregressas; 68% hipertensos; 73% dislipidêmicos; 11% coronariopatas; 4% apresentaram AVE e 64% faziam uso regular de hipolipemiantes. O teste de Fisher evidenciou diferentes RR em função da presença ou não de DCA: Hipotireoidismo (DCA vs NDCA, p< 0,555; RR=1,0); (DCA vs EMI, p < 0,0001; RR=5,2); Dislipidemia (DCA vs NDCA, p< 0,001; RR=1,62); HAS (DCA vs NDCA, p< 0,003; RR=1,76); DM (DCA vs NDCA, p< 0,001; RR=3,6); AVE (DCA vs NDCA, p< 0,0001; RR=2,03); DAC (DCA vs NDCA, p< 0,0001; RR=6,14). Predominaram estenoses leves em 44%, estenoses moderadas em 9%, não foram observados pacientes com estenose severa ou oclusão. A avaliação dos dados de colesterol livre e total de colesterol marcado na fração HDL diferiu entre os grupos estratificados por HDL-C maior e menor do que 40mg/dl e para as condições DCA e sem DCA (p = 0,0409 e, p = 0,0475 teste t), respectivamente. A análise de correlação linear de Pearson entre os dados de atividade de PON1 quando HDL-C < 40mg/dl e incorporação de colesterol livre e, também entre percentual de esterificação CL/CE foi significativa (r = -0,6; p = 0,048; n = 20 e r = -0,7; p = 0,006; n = 12), respectivamente. Conclusões: Evidenciado presença da DCA com aumento da idade conforme literatura; prevaleceu DCA no perfil clínico dos participantes do estudo; as doenças de base identificadas elevam o risco para DCA; o transporte reverso de colesterol é prejudicado na DCA.
Atherosclerosis is the leading cause death worldwide related from cardiovascular. Atherosclerosis is characterized by disturbance of mechanical and physiological condition, which promotes thickening and hardening of the coronary vessels, cerebral and peripheral inflammatory lesion causing chronic high-fat and abnormal cells in vascular walls. Objectives: Assess plasma concentrations of biomarkers of lipid metabolism and vascular echocardiography results of carotid artery linking them with the disease of the carotid atherogenic. Delineation: Cross-sectional observational study. Casuistry and Methods: 66 patients aged 57.5 ± 15.5 years (20-77), 63% female. Were used in the statistical analysis parametric tests and non-parametric, p-values <0.05 was considered significant. Results: It was found in the DCA from the male population age 36-45 years, in women, the disease could be detected from 46-55 years, rising in both genders as age increases. We had a higher prevalence of DCA among females (33% versus 15%), range 56-65 years, showing an RR of 1.56 for females (p <0.002, Fisher's test with approximation of Katz). As the clinical profile, there was prevalence from 53% patients with DCA, 82% patients were taking regular medication for any of the previous diseases, 68% hypertensive, 73% had dyslipidemia, and of those, 53% had evidence of DCA associated with. Coronary artery disease 11%, 4% had stroke and 64% were regularly taking lipid-lowering. The Fisher test showed different RR due to the presence or absence of DCA: The Fisher test showed different RR due to the presence or absence of DCA: Hypothyroidism (DCA vs NDCA, p <0.555, RR = 1.0), (DCA vs. EMI, p <0.0001, RR = 5.2) ; Dyslipidemia (DCA vs NDCA, p <0.001, RR = 1.62), hypertension (DCA vs NDCA, p <0.003, RR = 1.76), DM (DCA vs NDCA, p <0.001, RR = 3.6 ), stroke (DCA vs NDCA, p <0.0001, RR = 2.03), DAC (DCA vs NDCA, p <0.0001, RR = 6.14). Mild stenosis predominated in 44%, moderate stenosis in 9%. Were not seen patients with severe stenosis or occlusion. The evaluation of data from free cholesterol and total cholesterol HDL fraction differed marked on stratified groups and increased HDL-C less than 40mg/dl and conditions and without DCA (p = 0.0409 and p = 0, 0475 t-test), respectively. The analysis of Pearson's linear correlation between the data of PON1 activity when HDL-C <40mg/dl and incorporation of free cholesterol, and also between percentage of esterification CL / CE was significant (r = -0.6, p = 0.048 n = 20 and r = -0.7, p = 0.006, n = 12), respectively. Conclusions: Evidenced presence of DCA with increasing age according to the literature, DCA prevailed in the clinical profile of study participants, underlying diseases increase the risk identified for DCA, the reverse is impaired in DCA.
Haloui, Zoubida. "Effet de la mutation cat fraser sur la synthese des collagenes non fibrillaires et interstitiels chez la souris (cat fr)." Paris 7, 1987. http://www.theses.fr/1987PA077207.
Full textBarbieri, Paulo Duarte. "Explorando superpixels para a segmentação semiautomática de imagens médicas para recuperação por conteúdo." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/55/55134/tde-17112016-101608/.
Full textThis work presents the development of a semiautomatic vertebral body segmentation method VBSeg, which uses superpixels to increase effi- ciency of well established image segmentation methods without losing quality. Experiments have shown motivating results with superpixels im- proving vertebral bodies segmentation in 18% and making segmentation algorithms at least 38% faster. Furthermore, our VBSeg method has low dependency on the level of expertise and got similar results to Watershed method, a well-established image segmentation method. However, VB- Seg method was able to segment 100% of the analyzed vertebral bodies while Watershed method missed 44% of those.
Simonneaux, Valérie. "Role des compartiments juxta-epitheliaux - mucus et tissu sereux - dans l'iono- et l'osmo- regulation digestive chez l'anguille europeenne d'eau de mer." Université Louis Pasteur (Strasbourg) (1971-2008), 1987. http://www.theses.fr/1987STR13100.
Full textTorres, Geórgea Hermógenes Fernandes. "Associação de fraturas vertebrais moderadas e graves com menor densidade volumétrica trabecular na tíbia em mulheres idosas e menor densidade mineral óssea areal em fêmur em homens idosos da comunidade: São Paulo Ageing & Health study (SPAH)." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5166/tde-13022019-143204/.
Full textBackground: Many vertebral fractures (VF) occur in individuals classified by DXA as low risk for fragility fractures. Thus, the aim of this study was to verify the association between VF and peripheral bone microarchitecture and strength parameters using also high-resolution peripheral quantitative computed tomography (HR-pQCT) and axial bone microarchitecture by trabecular bone score (TBS). Study design: Cross-sectional study of 276 subjects aged >=65 years from SPAH cohort. Methods: Lateral scans of spine obtained from Vertebral Fracture Assessment by DXA were analyzed to assess VF. HR-pQCT was performed at radius and tibia. TBS was performed using DXA. Results: At tibia, women with Moderate/severe VF had lower volumetric bone density (vBMD), trabecular number (Tb.N), strength parameters and higher trabecular separation (Tb.Sp); and men had lower Tb.N, strength parameters and higher Tb.Sp. At radius, women with moderate/severe VF had lower v.BMD, trabecular and cortical thickness and strength parameters; and men had lower trabecular v.BMD and strength parameters. No differences were observed in TBS in both genders. Logistic regression analysis revealed that lower trabecular vBMD at tibia in women (OR: 0.980, 95%CI: 0.963-0.997, p = 0.022) and lower femoral neck aBMD and total hip in men (OR: 0.002, 95%CI: 0-0.607, p = 0.033 and OR: 0,003, IC 95%: 0-0,623, p = 0,033) were independently associated with VF. Conclusion: HR-pQCT images detected differences on bone microstructure in older women with moderate/severe VF independent of aBMD and TBS by DXA and HR-pQCT could be useful tool to assess fracture risk. Differently, in men femoral aBMD was associated with moderate/severe VF and DXA continue an important tool for predicting VF
Benaroch, Philippe. "Etude des mecanismes cellulaires de la suppression allotypique des immunoglobulines chez le lapin et chez la souris." Paris 6, 1988. http://www.theses.fr/1988PA066062.
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