Relevant bibliographies by topics / Veterinary toxicology

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Veterinary toxicology'

Author: Grafiati
Published: 4 June 2021
Last updated: 31 July 2024

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Journal articles on the topic "Veterinary toxicology"

1

Nebbia, Carlo. "Veterinary Toxicology." Veterinary Journal 164, no. 3 (November 2002): 187. http://dx.doi.org/10.1053/tvjl.2001.0685.

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Gabriel, Karl L. "VETERINARY TOXICOLOGY." Annals of the New York Academy of Sciences 111, no. 2 (December 15, 2006): 561. http://dx.doi.org/10.1111/j.1749-6632.1964.tb53122.x.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 82, no. 2 (March 1, 1999): 454. http://dx.doi.org/10.1093/jaoac/82.2.454.

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Nicholson, Steven S. "Clinical veterinary toxicology." Preventive Veterinary Medicine 33, no. 1-4 (January 1998): 319–20. http://dx.doi.org/10.1016/s0167-5877(97)00044-5.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 73, no. 1 (January 1, 1990): 143–46. http://dx.doi.org/10.1093/jaoac/73.1.143.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 74, no. 1 (January 1, 1991): 167–69. http://dx.doi.org/10.1093/jaoac/74.1.167.

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Ross, Frank P. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 75, no. 1 (January 1, 1992): 141–42. http://dx.doi.org/10.1093/jaoac/75.1.141.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 76, no. 1 (January 1, 1993): 165–67. http://dx.doi.org/10.1093/jaoac/76.1.165a.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 77, no. 1 (January 1, 1994): 199–201. http://dx.doi.org/10.1093/jaoac/77.1.199.

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Ross, P. Frank. "Veterinary Analytical Toxicology." Journal of AOAC INTERNATIONAL 78, no. 1 (January 1, 1995): 194–95. http://dx.doi.org/10.1093/jaoac/78.1.194.

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Dissertations / Theses on the topic "Veterinary toxicology"

1

Brown, Larry Dale. "Subchronic bioavailability and disposition of bivalent lead in pregnant swine and fetuses." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9901221.

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Siqueira, Adriana de. "Avaliação dos efeitos tóxicos dos carbamatos: I. Modelo experimental em ratos Wistar e comparação com a intoxicação exógena intencional em gatos e cães; II. Análise de estabilidade dos compostos e dos seus efeitos nos post mortem imediato e em animais exumados." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/10/10133/tde-31082015-142508/.

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A intoxicação intencional de animais e de pessoas é uma ameaça à saúde e à segurança públicas em todo o mundo. No Brasil, os pesticidas da classe dos carbamatos aldicarbe e carbofurano são facilmente obtidos, e uma única dose letal daqueles é facilmente misturada a alimentos palatáveis e iscas. Foram analisadas as necropsias de 26 gatos e 10 cães, da rotina do Serviço de Patologia Animal da FMVZ-USP, com variados intervalos post mortem e tipos de conservação de carcaça, intoxicados pelos carbamatos aldicarbe e carbofurano, confirmados pela cromatografia de camada delgada (CCD) e cromatografia líquida de alta performance com detector de arranjo de diodos (CLAE-DAD). Foram colhidas as matrizes biológicas para histopatologia e análise toxicológica. CLAE-DAD foi utilizada para detectar o aldicarbe e seus metabólitos, aldicarbe sulfóxido e aldicarbe sulfona, e carbofurano e seu metabólito 3-hidroxicarbofurano. As análises macroscópica e histopatológica revelaram predominantemente achados congestivos e hemorrágicos, o que pode ser resultante dos efeitos tóxicos dos carbamatos e seus metabólitos. Foram feitos 2 experimentos envolvendo exposição a uma dose única de carbofurano e de aldicarbe via gavagem em ratos Wistar. No primeiro, no qual foram avaliados os efeitos no post mortem imediato, 30 animais forma separados nos seguintes grupos: aldicarbe (n=10), carbofurano (n=10) e grupo controle (n=10). Os animais foram filmados para avaliar as alterações clínicas na intoxicação aguda e, quando foram sedados, foi colhido sangue por punção cardíaca para fazer o hemograma, bioquímica sérica, colinesterase e exame toxicológico e, após a eutanásia, foi feita a necropsia e colhido material para o exame histopatológico. Em todos os animais experimentais foi possível ser feita a detecção e a quantificação do aldicarbe e do carbofurano, além das alterações microscópicas congestivas e hemorrágicas, com alterações em parâmetros hematológicos e bioquímicos. No segundo experimento, foram utilizados 30 animais, e o protocolo experimental foi idêntico ao experimento anterior, exceto que, após o óbito, os animais foram colocados em uma caixa com terra nos seguintes grupos: 1 dia, 3 dias, 5 dias, 7 dias e 10 dias, e em cada dia foram agrupados 2 animais intoxicados e 1 controle, sendo que as necropsias foram feitas nestes intervalos. Foram colhidos cérebro, pulmão, fígado e rim ao exame histopatológico e globo ocular, conteúdo gástrico, fígado e músculo esquelético ao exame toxicológico. Foram observadas as alterações tanatológicas e, em todas as matrizes analisadas, puderam ser quantificados o aldicarbe e/ou seus metabólitos aldicarbe sulfóxido e aldicarbe sulfona, bem como o carbofurano e seu metabólito 3-hidroxicarbofurano. Estes estudos mostram a importância da necropsia e da coleta de matrizes diversas ao exame toxicológico, que são complementares e cruciais na investigação de óbitos decorrentes de intoxicações por praguicidas, tanto no post mortem imediato quanto em exumações
The intentional poisoning of animals and people is a threat to public health and safety worldwide. In Brazil, the carbamate pesticides aldicarb and carbofuran are easily obtained. A single lethal dose of these carbamates is easily mixed with palatable food or baits. Necropsies and histopathological examinations of 26 cats and 10 dogs poisoned by the carbamates aldicarb and carbofuran were performed in the Service of Animal Pathology of FMVZ-USP, and the poisoning was confirmed by thin layer chromatography (TLC) and high performance liquid chromatography with diode-array detector (HPLC-DAD), with variable post mortem interval and conservation of the carcass. Biological matrices were collected for histopathological and toxicological analysis. HPLC-DAD was utilised to detect aldicarb and its metabolites, aldicarb sulphoxide and aldicarb sulphone, and carbofuran and its metabolite 3-hydroxycarbofuran. Gross and histopathological evaluations showed mainly congestive and haemorrhagic findings, which may result from the toxic effects of the carbamates and their metabolites. Two experimental protocols were performed in Wistar rats by exposing them to a single oral gavage dose to the carbamates aldicarb and carbofuran. The first experiment was performed to evaluate the immediate post mortem effects of carbamates, and 30 rats were divided into three groups: aldicarb (n-=10), carbofuran (n=10) and control (n=10). The animals were filmed to evaluate the clinical signs of poisoning, and they were sedated to collect blood by heart puncture, to perform CBC, serum biochemistry, and to measure serum cholinesterase. After euthanasia, tissues were collected for histopathological evaluation. Aldicarb and carbofuran were detected and quantified in the blood of all experimental groups, and the most common histological changes observed were congestion and haemorrhage. In the second experiment, the experimental protocol was identical to the first one, but the animals were buried in a plastic box with garden soil within 5 groups of 3 animals, two exposed to the same pesticide and 1 control, as follows: day 1, day 3, day 5, day 7 and day 10. The exhumations were performed within these days (1, 3, 5, 7 and 10). We collected brain, lung, liver and kidney to examine the thanatological changes, and the eyeballs, gastric content, liver and skeletal muscle to perform the toxicological screening. Thanatological changes could be observed within and between the groups, and, in all the matrices we could detect aldicarb and its metabolites aldicarb sulphoxide and aldicarb sulphone, and carbofuran and its metabolite 3-hydroxycarbofuran. The studies have shown the importance of the necropsy and the collection of diverse matrices to the toxicological screening, because both are complementary and crucial to the investigation of deaths by pesticides poisoning, even in exhumation, since we could evaluate the thanatological changes and correlate them to the action of the pesticides in the tissues
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Dimande, Alberto Francisco Paulo. "The toxicity of Senecio inaequidens DC." Diss., Electronic thesis, 2007. http://upetd.up.ac.za/thesis/available/etd-05122008-080613/.

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Zuanaze, Rita de Cássia Collicchio [UNESP]. "Perfil hematológico, bioquímico, histopatológico e toxicológico de gatos induzidos experimentalmente com monofluoroacetato de sódio." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/101302.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação para o Desenvolvimento da UNESP (FUNDUNESP)
O monofluoroacetato de sodio (MFAS) ou composto 1080 e um rodenticida que foi amplamente utilizado para o controle de roedores e predadores domesticos, apos sua descoberta em 1945. Este potente rodenticida age bloqueando o ciclo de Krebs por acao do seu metabolito toxico, o fluorocitrato, e como consequencia, inibe a resposta celular e a producao de ATP. O MFAS foi proibido por lei no Brasil e em diversos paises, mas seu uso indiscriminado continua causando diversos casos de intoxicacoes potencialmente fatais no homem e animais domesticos, principalmente em caes e gatos, representadas por alteracoes neurologicas e cardiacas. Pretendeu-se com este estudo caracterizar o perfil hematologico e bioquimico, as alteracoes histopatologicas e toxicologicas de gatos intoxicados experimentalmente com MFAS, com o objetivo de determinar metodos diagnosticos eficazes. Para tanto, foram utilizadas amostras de sangue de 16 gatos intoxicados experimentalmente com 0,45mg/kg de MFAS, por via oral. Estas amostras foram colhidas por puncao jugular e analisadas quanto ao perfil hematologico, bioquimica serica e analises toxicologicas em cromatografia liquida de alta eficiencia (CLAE), para deteccao e quantificacao do MFAS no soro dos animais. Avaliaram-se tambem as lesoes macro e microscopicas dos animais intoxicados que vieram a obito. Observaram-se leucopenia e trombocitopenia transitorias; hiperglicemia, aumento das enzimas musculares creatinoquinase (CK) e creatinoquinase fracao cardiaca (CK-MB); observaram-se tambem hipocalemia, hipofosfatemia e hipomagnesemia. Os achados macroscopicos e histopatologicos demonstraram lesoes caracteristicas de processos isquemicos e as analises toxicologicas demonstraram um metodo diagnostico simples e eficiente...
Sodium monofluoroacetate (SMFAC) or 1080 compound is a potent rodenticide, largely used since 1945 for rodent and domestic pest control. The toxic effects of SMFAC are caused by fluorocitrato, a toxic metabolite, which has a competitive action with aconitase enzyme, leading to citrate accumulation and interferes in energy production by Krebs cycle blockade. In Brazil, although prohibited by law, there is illegal use, keep causing intoxication in children and domestic animals, specially dogs and cats. The most common intoxication clinical signs are from the cardiac and neurological alterations. In the present study, 16 domestic cats were intoxicated with oral doses of monofluoroacetate (0.45mg/kg). The hematologic and biochemical profiles, and histophatological and blood serum toxicological analysis by high performance liquid chromatography (HPLC) were made to looking for a efficient diagnosis methods. The hematologic profile showed transitory leucopenia and trombocitopenia; the biochemical profile presented hiperglycemia, increase of creatinoquinase enzyme (CK) and creatinoquinase cardiac fraction (CK-MB), hypokalemia and hypophosfatemia were observed. The macrocospic and histopathological findings showed lesions characteristic of degenerative and ischemic processes. The toxicological analysis was shown to be a simple and efficient diagnostic method. SMFAC was detected in 75% of the serum samples analysed, and it was verified an average concentration of 0.32 ìg/mL in them; 4.81% of the serum samples did not show metabolized SMFAC six hours after the induced intoxication of the animals used in this study.
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Zuanaze, Rita de Cássia Collicchio. "Perfil hematológico, bioquímico, histopatológico e toxicológico de gatos induzidos experimentalmente com monofluoroacetato de sódio /." Botucatu : [s.n.], 2006. http://hdl.handle.net/11449/101302.

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Orientador: Michiko Sakate
Banca: Noeme Sousa Rocha
Banca: Manoel Lima de Menezes
Banca: Mara Regina Stipp Balarin
Banca: Silvana Lima Gorniak
Resumo: O monofluoroacetato de sodio (MFAS) ou composto 1080 e um rodenticida que foi amplamente utilizado para o controle de roedores e predadores domesticos, apos sua descoberta em 1945. Este potente rodenticida age bloqueando o ciclo de Krebs por acao do seu metabolito toxico, o fluorocitrato, e como consequencia, inibe a resposta celular e a producao de ATP. O MFAS foi proibido por lei no Brasil e em diversos paises, mas seu uso indiscriminado continua causando diversos casos de intoxicacoes potencialmente fatais no homem e animais domesticos, principalmente em caes e gatos, representadas por alteracoes neurologicas e cardiacas. Pretendeu-se com este estudo caracterizar o perfil hematologico e bioquimico, as alteracoes histopatologicas e toxicologicas de gatos intoxicados experimentalmente com MFAS, com o objetivo de determinar metodos diagnosticos eficazes. Para tanto, foram utilizadas amostras de sangue de 16 gatos intoxicados experimentalmente com 0,45mg/kg de MFAS, por via oral. Estas amostras foram colhidas por puncao jugular e analisadas quanto ao perfil hematologico, bioquimica serica e analises toxicologicas em cromatografia liquida de alta eficiencia (CLAE), para deteccao e quantificacao do MFAS no soro dos animais. Avaliaram-se tambem as lesoes macro e microscopicas dos animais intoxicados que vieram a obito. Observaram-se leucopenia e trombocitopenia transitorias; hiperglicemia, aumento das enzimas musculares creatinoquinase (CK) e creatinoquinase fracao cardiaca (CK-MB); observaram-se tambem hipocalemia, hipofosfatemia e hipomagnesemia. Os achados macroscopicos e histopatologicos demonstraram lesoes caracteristicas de processos isquemicos e as analises toxicologicas demonstraram um metodo diagnostico simples e eficiente...(Resumo completo, clicar acesso eletrõnico abaixo)
Abstract: Sodium monofluoroacetate (SMFAC) or 1080 compound is a potent rodenticide, largely used since 1945 for rodent and domestic pest control. The toxic effects of SMFAC are caused by fluorocitrato, a toxic metabolite, which has a competitive action with aconitase enzyme, leading to citrate accumulation and interferes in energy production by Krebs cycle blockade. In Brazil, although prohibited by law, there is illegal use, keep causing intoxication in children and domestic animals, specially dogs and cats. The most common intoxication clinical signs are from the cardiac and neurological alterations. In the present study, 16 domestic cats were intoxicated with oral doses of monofluoroacetate (0.45mg/kg). The hematologic and biochemical profiles, and histophatological and blood serum toxicological analysis by high performance liquid chromatography (HPLC) were made to looking for a efficient diagnosis methods. The hematologic profile showed transitory leucopenia and trombocitopenia; the biochemical profile presented hiperglycemia, increase of creatinoquinase enzyme (CK) and creatinoquinase cardiac fraction (CK-MB), hypokalemia and hypophosfatemia were observed. The macrocospic and histopathological findings showed lesions characteristic of degenerative and ischemic processes. The toxicological analysis was shown to be a simple and efficient diagnostic method. SMFAC was detected in 75% of the serum samples analysed, and it was verified an average concentration of 0.32 ìg/mL in them; 4.81% of the serum samples did not show metabolized SMFAC six hours after the induced intoxication of the animals used in this study.
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Rawal, Sumit. "Mechanisms of the Extreme Sensitivity of Turkeys to Aflatoxin B1." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/568.

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The pathogenesis of hepatotoxic and hepatocarcinogenic actions of the mycotoxin aflatoxin B1 (AFB1) involves initial bioactivation by microsomal cytochrome P450s (P450) to a reactive and electrophilic intermediate, exo-aflatoxin B1-8,9-epoxide (exo-AFBO). Poultry, especially turkeys, are extremely sensitive to AFB1, a condition associated with efficient epoxidation by P450s. The purpose of this research was to 1) discover and characterize the P450s in turkey liver responsible for AFB1 bioactivation, and 2) determine the relative importance of these P450s in turkey liver. Initial investigations led to the discovery of CYP1A5. We then identified CYP3A37, a human CYP3A4 homologue from turkey liver, which along with CYP1A5 plays an important role in the bioactivation of AFB1 to exo-AFBO. The E. coli-expressed CYP3A37 possessed striking similarities to human CYP3A4, in terms of its catalytic activities and the kinetics of AFB1 oxidation. After the discovery of CYP3A37, further research evaluated its relative importance to CYP1A5, with respect to the epoxidation of AFB1, to determine which of the homologues bioactivated relatively low "real world" AFB1 concentrations, reflective of the potential dietary exposure. Using antibodies directed to both the enzymes as tools in immuno-inhibition experiments, we determined that CYP1A5 contributes to about 98% of the exo-AFBO formation at the low AFB1 concentrations (0.1 µM), which led us to conclude that CYP1A5 is likely the dominant homologue involved in the extreme sensitivity of the turkeys to AFB1. CYP3A37 also efficiently epoxidated AFB1, but only at high concentrations of this mycotoxin, not likely to be achievable in turkey liver in vivo. Our research has helped shed light on the relative importance of CYP1A5 and CYP3A37 in the bioactivation of AFB1 to the toxic exo-AFBO, and thus on the mechanisms of the extreme sensitivity of turkeys to AFB1. Given that AFB1 is a ubiquitous component of corn-based poultry feed and contamination is practically unavoidable, we conducted further studies evaluating the chemopreventive action of probiotic bacteria, Lactobacillus, on AFB1 toxicity in turkeys. Probiotic bacteria are known to bind AFB1, thus reducing its bioavailability. A mix of probiotic bacteria provided protection against key endpoints of aflatoxicosis, like AFB1-induced reduction in body and liver weights. Our data demonstrate that Lactobacillus was protective against aflatoxicosis in turkeys, thus validating its use as a possible chemopreventive, thereby helping alleviate the significant annual losses to the poultry industry due to feed contamination by AFB1.
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CAMBOIM, Expedito Kennedy Alves. "Bactérias que degradam Monofluoroacetato de Sódio." Universidade Federal de Campina Grande, 2012. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/1636.

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O objetivo deste trabalho foi isolar e identificar bactérias capazes de degradar fluoroacetato de sódio (FS) em amostras de solo e plantas, coletadas em áreas onde são encontradas plantas que contêm fluoroacetato tais como Mascagnia rigida e Palicourea aenofusca. As amostras foram cultivadas em meio mineral acrescido de 20 mmol L−1 de fluoroacetato de sódio. Através do sequenciamento do gene 16S rRNA os sete isolados foram identificados como Paenibacillus sp. (ECPB01), Burkholderia sp. (ECPB02), Cupriavidus sp. (ECPB03), Staphylococcus sp. (ECPB04), Ancylobacter sp. (ECPB05), Ralstonia sp. (ECPB06), e Stenotrophomonas sp. (ECPB07). Todos os sete isolados degradaram o FS contido no meio, alcançando uma taxa de degradação de 20 mmol L−1 de íon flúor. Dos isolados, seis são descritos pela primeira vez como capazes de degradar FS. No futuro, alguns destes microorganismos podem ser utilizados para estabelecer no rúmen uma população bacteriana capaz de degradar o fluoroacetato de sódio e proteger ruminantes de intoxicações por este composto.
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Thomas, Sarah Elizabeth. "A Prevalence Study of Southeast Origin Sale Barn Beef Cattle, Comingled in Warren County, Kentucky, Persistently Infected with Bovine Viral Diarrhea Virus, including the Effects of Season and Body Weight." TopSCHOLAR®, 2011. http://digitalcommons.wku.edu/theses/1070.

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Bovine viral diarrhea (BVD) is an economically important disease of cattle. Calves persistently infected (PI) with the bovine viral diarrhea virus (BVDV) are a powerful agent for spread of the virus. A total of 24,423 southeast origin beef cattle comingled at three Warren County, Kentucky locations were tested from November 2007 to June 2010 for PI BVDV. A total of 97 head tested positive for PI BVDV, giving an average overall prevalence of 0.397%. Calves tested were subdivided into categories for additional calculations of dependence. A total of 8,910 were categorized by weight range upon testing (300-399 lbs, 400-499 lbs, 500-599 lbs, and 600-699 lbs). Prevalence does show a dependence on weight, with a higher prevalence found in lower weight classes, especially 300-399 lb calves (P<0.001). A total of 24,423 were categorized by season at time of testing (Fall, Winter, Spring, Summer). Prevalence does not show a dependence on season (P>0.05). Although eradication programs are not likely to be organized in the United States, several control programs have been developed. These findings can be used as additional support for PI testing of calves, especially those in lighter weight classes, as part of a BVD control program.
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Monteiro, Davolli Gabriel. "REVERSIBLE DOWNREGULATION OF HYPOTHALAMIC-PITUITARY-GONADAL AXIS IN THE STALLION WITH A THIRD-GENERATION GNRH ANTAGONIST." UKnowledge, 2015. http://uknowledge.uky.edu/gluck_etds/22.

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The objectives of this thesis were: (1) to evaluate the downregulation of the stallion hypothalamic-pituitary-gonadal (HPG) axis by a GnRH antagonist (acyline) based upon endocrine, seminal, testicular and behavioral effects, and (2) to assess recovery after treatment. Stallions were treated for 50 days (n=4; 330µg/kg acyline q 5d) and controls (n=4) received vehicle alone. Stallions were assessed pre-treatment and for 72 days after last treatment. Treatment induced declines (p<0.05) in FSH, LH, testosterone (to castrate levels) and estrone sulfate. Gonadotropins and testosterone returned to control values within nine days and estrone sulfate by 14 days after treatment discontinuation. Acyline-treated stallions failed to respond with FSH, LH and testosterone increase after exogenous GnRH stimulation (25µg gonadorelin, IV) compared to pre-treatment and control stimulation. Total sperm numbers and motility were reduced in acyline-treated stallions, as well as total seminal plasma protein and testicular volume (p<0.05). Time to ejaculation was increased in acyline group (p<0.5). Testicular, sexual behavior and most seminal parameters regained normal levels within 72 days after treatment ceased. Sperm output of acyline-treated stallions was regained within seven months after ending treatment. Acyline reversibly suppressed the stallion HPG axis, thus has potential for treating the androgen-dependent Equine-Arteritis-Virus carrier state and as behavior modulator.
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Zhu, Wenying. "GLUCOCORTICOID-INDUCED CHONDROCYTE CYTOTOXICITY AT DOSES RECOMMENDED FOR INTRA-ARTICULAR THERAPY IN HORSES." UKnowledge, 2015. http://uknowledge.uky.edu/gluck_etds/23.

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Intra-articular glucocorticoid injections are commonly used to treat synovitis and osteoarthritis in horses. These agents are highly effective at relieving pain, swelling, and other symptoms of joint inflammation. The drugs also have therapeutic benefits by down regulating the expression of cytokines and protease enzymes that participate in the degradation of articular cartilage. However, detrimental effects on chondrocyte function and cell viability that is independent of osteoarthritis pathogenesis have been described and linked to glucocorticoid use. These side effects are both drug- and dose-dependent. This study tested the hypothesis that manufacture recommended dosage levels of methylprednisolone, betamethasone, and triamcinolone that are widely used in equine clinical practice are cytotoxic to articular chondrocytes. Drug-induced chondrocyte cytotoxicity was evaluated in monolayer cultures, cartilage explants, and equine fetlock joints. Total RNA was isolated from control and IL-1β stimulated primary chondrocytes and synoviocytes in culture. Changes in steady state mRNA for targeted gene transcripts related to inflammation and normal cell function were measured using reverse transcription and quantitative PCR. Inducible nitric oxide synthase activity was evaluated using nitrite production. Drug-induced chondrocyte cytotoxicity occurred at drug dosage levels frequently used in equine clinical practice. Both drug- and dose-dependent effects on chondrocyte and synoviocyte gene expression were observed. Maximum anti-inflammatory activities for the glucocorticoids were observed at in vitro concentrations below manufacturer-recommended levels. Results from this study suggest that lower glucocorticoid dose ranges for intra-articular therapy in horses should be validated to maximize the ratio of their therapeutically beneficial anti-inflammatory efficacy against detrimental effects on cell function and viability.
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Books on the topic "Veterinary toxicology"

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Roder, Joseph D. Veterinary toxicology. Boston: Butterwoth-Heinemann, 2001.

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Tiwari, Radhey Mohan. Veterinary toxicology. Jaipur, India: Oxford Book, 2009.

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Humphreys, D. J. Veterinary toxicology. 3rd ed. London: Bailliére Tindall, 1988.

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Parton, K. Veterinary clinical toxicology. 2nd ed. Palmerston North: Veterinary Continuing Education, Massey University, 2001.

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Bruère, A. N. Veterinary clinical toxicology. Palmerston North, N.Z: Veterinary Continuing Education, Massey University, 1990.

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Konnie, Plumlee, ed. Clinical veterinary toxicology. St. Louis, Mo: Mosby, 2004.

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Peterson, Michael E. Small animal toxicology. 2nd ed. St. Louis, Mo: Saunders/Elsevier, 2006.

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D, Osweiler Gary, ed. Clinical and diagnostic veterinary toxicology. 3rd ed. Dubuque, Iowa: Kendall/Hunt Pub. Co., 1985.

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Lorgue, G. Clinical veterinary toxoicology. Osney Mead, Oxford [England]: Blackwell Science, 1996.

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European Association for Veterinary Pharmacology and Toxicology Congress (3rd 1985 Ghent, Belgium). Comparative veterinary pharmacology, toxicology and therapy. Boston: MTP Press, 1985.

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Book chapters on the topic "Veterinary toxicology"

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Rogers, Ernest R. "Veterinary Forensic Toxicology." In Veterinary Forensics, 329–48. Boca Raton, FL : CRC Press, 2018.: CRC Press, 2017. http://dx.doi.org/10.4324/9781315153421-13.

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Gupta, PK. "Veterinary Clinical Toxicology." In Concepts and Applications in Veterinary Toxicology, 309–28. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-22250-5_15.

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Brutlag, Ahna. "Toxicology." In Cannabis Therapy in Veterinary Medicine, 61–83. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-68317-7_3.

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Dorman, David C. "Veterinary toxicology." In Information Resources in Toxicology, 635–40. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-813724-6.00064-5.

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Gupta, PK. "Veterinary toxicology." In Illustrated Toxicology, 427–517. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-12-813213-5.00015-8.

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Rumbeiha, Wilson K., and Frederick W. Oehme. "Veterinary Toxicology." In Encyclopedia of Toxicology, 420–34. Elsevier, 2005. http://dx.doi.org/10.1016/b0-12-369400-0/01004-8.

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Rumbeiha, W. K., and D. B. Snider. "Veterinary Toxicology." In Encyclopedia of Toxicology, 915–28. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-386454-3.00444-9.

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H Poppenga, Robert, and Wayne Spoo. "Veterinary Toxicology." In Information Resources in Toxicology, 515–22. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-12-373593-5.00061-6.

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Oehme, Frederick W. "Veterinary toxicology." In Veterinary Toxicology, 3–7. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-385926-6.00001-6.

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Rumbeiha, Wilson K. "Veterinary toxicology." In Reference Module in Biomedical Sciences. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-824315-2.00719-3.

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Conference papers on the topic "Veterinary toxicology"

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Shumilina, M. A., K. A. Nefedova, and A. L. Zolkin. "VETERINARY EDUCATION AS A COMPONENT OF MODERN HIGHER SCHOOL IN RUSSIA: A BRIEF RETROSPECTIVE FLASHBACK OF PRE-INDUSTRIAL DEVELOPMENT." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-247-249.

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The article provides a brief historical event series of the formation of the modern appearance of higher veterinary education in Russia - in the Russian Empire and Soviet Russia. Some institutional measures for the formation of a higher school of veterinary medicine, which served as the basis for the subsequent development of veterinary medicine as a scientific direction, are considered. Key words: veterinary
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Moiseeva, A. A., V. N. ,. Skvortsov, and A. A. Prisnyi. "EFFECT OF ENROFLOXACIN ON WHITE BLOOD CELL DYNAMICS IN YOUNG POULTRY." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-168-170.

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Analysis of hematological profile of poultry may serve as a tool for monitoring the impact of various medicinal drugs on the organism and for detection of their unknown effects. We studied the obtained blood parameters while bearing in mind our goal to extend knowledge of the impact of fluoroquinolones on the organism of different kinds of poultry in view of certain lack of such knowledge especially for poultry of young ages.
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Lutsko, T. P., A. V. Osipova, and D. A. Skvortsov. "FEATURES OF CONCENTRATION OF SOME HEAVY METALS BY SORBENTS BASED ON VERMICULITE IN HYDROSPHERE OBJECTS." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-151-151.

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The problem of water quality occupies a crucial place in the system of nature protection and public health. Due to anthropogenic activities, heavy metals are one of the most common pollutants of natural waters. The natural mineral vermiculite has proven to be an effective absorber of trace amounts of heavy metals.
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Yeganyan, E. S. "STUDY OF THE EMBRYOTOXIC AND TERATOGENIC EFFECTS OF THE FEED ADDITIVE ABIOPEPTIDE-PLUS." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-74-76.

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The author of this article studied the embryotoxic and teratogenic properties of the feed additive Abiopeptide-plus on chicken embryos. It was found that the feed additive does not have negative consequences in the development of chicken embryos and contributes to the formation of a healthy full-fledged chicken.
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Kraskov, D. A., and T. P. Lutsko. "TOXIC-ECOLOGICAL ANALYSIS OF WATER IN THE GULF OF FINNISH." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-153-154.

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The Gulf of Finland plays an important role in many aspects of the activities of people living in St. Petersburg and the Leningrad region, based on this, it is necessary to control the chemical composition of the waters of the Gulf of Finland in order to avoid unwanted complications from animal health.
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Lutsko, T. P., A. G. Polyanskikh, E. S. Kuzmina, and I. D. Volobuev. "COMPARATIVE ANALYSIS OF THE HYDROCHEMICAL INDICATORS OF THE WATERS OF THE FINSKIY BAY IN THE AREA OF ST. PETERSBURG." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-150-151.

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Now the Finskiy bay is actively used for the everyday needs of the population of St. Petersburg. Therefore, in various districts of the city, a hydrochemical analysis of the waters of the Finskiy bay was carried out and the concentrations of nitrates, nitrites, ions of copper, iron, silicon, ammonium, as well as carbonate hardness and pH were determined. As a result of the study, it was found that all studied parameters, except for iron ions, do not exceed the MPC.
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A. A., Belov, A. V. Deryugina, and M. N. Ivashchenko. "CORRECTION OF TECHNOLOGICAL STRESS BY LOW-INTENSITY LASER RADIATION." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-24-25.

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Intensive industrial technologies in animal husbandry lead to an increase in cases of stress and metabolic disorders, which affects the quality of dairy and meat products. It is important to increase the resistance of animals to environmental factors by non-drug methods. The aim of the work is to study the effect of technological stress and low-intensity laser radiation at the cell level.
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Brigida, A. V., and O. A. Skachkova. "THE RELEVANCE OF THE APPLICATION OF FSH FOR SUPEROVULATION OF DONOR COWS AND WAYS OF INCREASING ITS EFFICIENCY." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-28-30.

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In the technology of cattle embryo transplantation, the classic protocol for superovulation of embryo donor cows is used, based on 8-10-fold administration of follicle-stimulating hormone (FSH) every 12 hours for 4-5 days. For many decades of using this technology, the yield of high- quality embryos varies within 4-6 pcs. It is necessary to increase the effectiveness of FSH to increase the number of embryos. We conducted a study of the effectiveness of a pharmacological composition consisting of FSH combined with polyethylene glycol (PEG) with a molecular weight of 6000 Da, which increases the yield of the number of embryos obtained, suitable for transplantation into recipients, or their cryopreservation
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Kuzmina, T. I., D. N. Tatarskaya, and V. YU Kravtsov. "PROSPECTS FOR THE USING OF SILICON-CONTAINING COMPOUNDS IN THE TECHNOLOGY OF IN VITRO MATURATION OF ANIMAL OOCYTES." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-129-131.

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In vitro production of animal embryos is an important tool for solving male and female infertility problems in animals. Modeling of extracorporeal maturation systems of oocytes using siliconcontaining compounds in the composition of culture media revealed the peculiarities of the realization of their effects on somatic and germ cells of ovarian follicles, depending on the structure. Highly dispersed silica nanoparticles (nHDS) positive effects on the fertility of female gametes in Bos Taurus and Sus Scrofa Domesticus. The gel substrate of silica (silicon dimethylglycerolate - DMGC) does not cause an increase in the level of embryos cleavage, while it does not have cytoand genotoxicity when tested on somatic and germ cells of antral follicles.Key words: siliconcontaining compounds, in vitro maturation, animal oocytes.
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Sakhno, T. A., M. P. Semenenko, and V. N. Grin. "DYNAMICS OF BIOCHEMICAL INDICATORS OF BLOOD IN FRESH COWS ON THE BACKGROUND OF HEPATOPROTECTOR APPLICATION." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-211-212.

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The influence of a new injectable hepatoprotective drug livasen in the prevention of hepatosis in highly productive fresh cows has been studied. The performed pharmacoprophylaxis has shown high efficiency in the correction of diseases of the hepatobiliary system and metabolic insufficiency.
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