Dissertations / Theses on the topic 'Vin de primeur'
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Hadj, Ali Héla. "La commercialisation des vins "en primeur"." Toulouse 1, 2002. http://www.theses.fr/2002TOU10071.
Full textThis thesis deals with the "en primeur" wine sales which is a form of forward market where producers sell in advance a part of their new production. The first chapter describes the "en primeur" sales and presents the literature related to the roles of some financial markets. The second chapter uses data from Bordeaux market to justify the recent speculative interest in wine sales. Results show that there is little evidence of improvement from adding wines to financial portfolio while investment in the "en primeur" market provides significantly higher returns than investment in financial markets. The third chapter studies the role of "en primeur" sales to finance producers who face liquidity problem. In a model with credit rationing, we study the role of certification by trade. Collusion is shown to prevent certification. "En primeur" sales are used only to solve the credit rationing problem. In the fourth chapter, we justify buy-in-advance offers because they provide insurance when there is some uncertainty about the demand of the good. We show that because the monopoly faces a commitment problem, these offers must entail some rationing. Moreover, any risk-averse producer chooses to propose an introductory offer, with rationning, while a risk-neutral producer prefers not to do so. Hence ? demand rationing may occur for insurance motives
Siqueira, Cassiano Medeiros. "Deus e o primeiro motor movente : uma análise lógica da primeira via de Tomás de Aquino." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/71940.
Full textAmong the five proofs of God’s existence presented by Thomas Aquinas in his Summa Theologiae, the so-called "first way" stands out, for being considered by the author as the "most obvious" one. This dissertation formalizes it in quantificational logic, explaining each of the inferences in order to assess its validity and soundness. After explaining the metaphysical theses that provide the backdrop for the discussion — as the doctrine of the four Aristotelian causes and the distinctions between substance and accident, act and potency — it considers the objections of Anthony Kenny (1969) and interpretive suggestions of John Wippel (2000) in defense of Thomas’ reasoning. It is shown that the first part, which seeks to demonstrate the non-reflexivity of movement, is a valid argument, but unsound, because it contains a false premise: the one that states the mover’s actuality without restrictions. The second part, the argument against the infinite regress, contains an ambiguity that leaves you faced with two alternatives: either it begs the question or it is a fallacy of equivocation. Given the material and formal failure of the proof, a non-deductive approach to the problem is finally proposed.
Olivier, Melani. "Die ontwikkeling en toepassing van 'n voorlopige meetinstrument vir die bepaling van primêre sorggewers se behoeftes rakende die hantering van die persoon met 'n traumatiese breinbesering." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-05152007-084141.
Full textVan, Wyk Milton Lester. "Die geleerde ervarings van primere skoolonderwysers binne 'n kultuur van performatiwiteit." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96995.
Full textENGLISH ABSTRACT: This study focuses on the lived experiences of primary school teachers within a culture of performativity. The French philosopher, Jean-Francois Lyotard (1984) more than anyone else gave credence to the notion of ‘performativity’ in education which he used to represent political and bureaucratic mechanisms of control. Embedded in regulatory mechanisms there are performance indicators such as ‘monitoring systems’ with associated ‘production of information’, that according to Ball (2003) engenders the ‘terrors of performativity’. To conform to the regulatory mechanisms the performativity culture in schools, pressure is increasingly placed on teachers to demonstrate their accountability to education authorities for the responsibilities delegated to them. The literature review does not only seeks to give meaning to key terms and concepts relevant to the study, but also aims to define the operational. Relevant terms included: accountability, professionalism, performance and performativity. In the discussion it is shown that there is a close underlying relationship between performativity and performance, between performativity and accountability, and between performativity and professionalism. In order to answer the main research question and to align logically to the purpose of the study, the researcher conducted a qualitative research study within the interpretative research paradigm. The study was guided by the phenomenological research approach – and more specifically by the hermeneutical-phenomenological research method of Max van Manen (1990). Two data collection methods were employed: protocol narratives (descriptions of lived experiences) and in-depth semi-structured phenomenological interviews. In this study a thematic analytical approach was followed whereby the researcher identified emerging themes from the collected data. Different steps were taken to increase the internal validity of the study and to give attention to the ethical aspects that emerged during the investigation. In this study it is evident that performativity, with its emphasis on effectiveness, efficiency and quality, is currently the most powerful and pervasive discourse in education. The description of the results shows that teachers tend to be swallowed up by the demands of performativity – so much so that teachers are overwhelmed by the ‘terrors of performativity’. Teachers’ ‘escape’ from the ‘imprisonment’ of performativity is not only associated with distorted side Stellenbosch University https://scholar.sun.ac.za viii effects, but there are also physiological and emotional processes that teachers are confronted with in their attempts conform to the regulatory systems. The study found that the undesirable side effects of performativity serve and a push factor for the early exit of teachers from the profession.
AFRIKAANSE OPSOMMING: Hierdie studie fokus op die geleefde ervarings van primêre skoolonderwysers binne ‘n kultuur van performatiwiteit. Die Franse filosoof, Jean-Francois Lyotard (1984) wat meer as enigeen die betekenis van performatiwiteit in die onderwys blootgelê het, gebruik die nosie van ‘performatiwiteit’ om politieke en burokratiese meganismes van beheer voor te stel. Ingebed in die regulerende meganismes is daar prestasie-aanduiders soos onder andere ‘moniteringsisteme’ met gepaardgaande ‘produksie van inligting’, wat volgens Stephen Ball (2003) aanleiding gee tot die ‘terreurs van performatiwiteit’. Ten einde te konformeer tot die regulerende meganismes is daar binne die performatiewe klimaat in die skool toenemende druk op onderwysers om te demonstreer dat hulle toerekenbaar is aan die onderwysowerhede vir die verantwoordelikhede wat aan hulle opgedra is. In die lieratuuroorsig is nie net ‘n oorsig gegee van die betekenisse van kernterme en – konsepte wat relevant tot hierdie studie is nie, maar ook is gepoog om dit operatief te definieer. Relevante begrippe is onder andere toerekenbaarheid, professionalisme, prestasie en performatiwiteit. In die bespreking is aangetoon dat daar ‘n noue onderlinge verband tussen performatiwiteit en prestasie, tussen performatiwiteit en toerekenbaarheid, en tussen performatiwiteit en professionalisme bestaan. Om die sentrale navorsingsvraag te beantwoord en logies met die doel van die studie in te skakel, het die navorser ‘n kwalitatiewe navorsingstudie uit die interpretiwistiese navorsingsparadigma onderneem. Die fenomenologiese navorsingsbenadering – en meer spesifiek, die hermeneuties-fenomenologiese navorsingsmetode van Max van Manen (1990) het hierdie studie gerig. Daar is gebruik gemaak van twee data-insamelingsmetodes, te wete protokol skryfwerk (geleefde ervarings-beskrywings) en semi-gestruktureerde in-diepte fenomenologiese onderhoude. In hierdie studie is ‘n tematiese analitiese benadering gevolg deurdat die navorser die ontluikende temas in die ingesamelde data geïdentifiseer het. Verskillende stappe is gedoen om veral die interne geldigheid van die studie te verhoog en aandag te gee aan etiese aspekte wat tydens die ondersoek na vore gekom het. Uit hierdie studie blyk dit dat performatiwiteit, met sy klem op effektiwiteit, doeltreffendheid en kwaliteit, huidiglik die mees magtigste en deurdringende diskoers in die onderwys is. Uit die Stellenbosch University https://scholar.sun.ac.za vi beskrywing van die resultate is dit duidelik dat onderwysers neig om deur die eise van performatiwiteit verswelg te raak – soveel so dat onderwyser oorweldig word deur die ‘terreurs van performatiwiteit’. Onderwysers se ‘ontsnapping’ uit die ‘gevangenskap’ van performatiwiteit gaan nie net gepaard met bepaalde verwronge opvoedkundige newe-effekte nie, maar ook is daar die fisiologiese en emosionele prosesse wat onderwysers moet verduur in hul pogings om tot die regulerende stelsels te konformeer. In die studie is bevind dat die ongewenste newe-effekte van performatiwiteit dien as stootfaktore wat onderwysers beweeg om die onderwys vroeg te laat verlaat.
Engelbrecht, Adel. "Ontwerp en toetsing van 'n intervensieprogram vir gesyferdheid vir graad 2- en 3-leerders." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/1623.
Full textENGLISH ABSTRACT: Learning and the development of numeracy in the foundation phase are regarded as highly important. In this critical period learners attain the fundamental knowledge that is needed for future learning and development. A serious problem within South African schools is that a great number of foundation phase learners show difficulties in numeracy. Various reasons can be provided for these difficulties, for example, learners do not receive good teaching, they hold negative attitudes towards numeracy, they encounter language barriers, and so forth. It is important that the learners’ difficulties in numeracy are attended to immediately and effectively, to be able to minimise the gaps between the learners’ functioning level and the level the learner is suppose to be on. The Western Cape Education Department (WCED) laid bare their concern with the current problem in numeracy when they launched the WCED Literacy and Numeracy Strategy 2006-2016. As part of this the Metropole North Education and Management Development Centre (EMDC) requested and implemented an intervention programme for grade 2 and grade 3 learners. Part of this problem is that many foundation phase educators lack the necessary knowledge to identify the learners with difficulties and especially to attend to these difficulties. The goal of this research study was to investigate the realization of an early intervention programme implemented over a limited period of time of ten weeks in grade 2 and grade 3 classrooms. The current study aimed at providing educators with resources to offer learning support to their disadvantaged learners within the Numeracy classroom. This study has implications for the way in which educators approach and teach numeracy, as well as for the type of learning support the educators provide their disadvantaged learners with. The intervention programme is based on a problem centered approach with constructivism as underlying epistemology. This approach views the educator as a facilitator who provides the learners with opportunities to be actively involved in the learning environment to construct knowledge. The importance of word problems and discussion within the Numeracy classroom are emphasized and it is necessary that the educator create the appropriate classroom atmosphere so that this approach can be implemented effectively. Learning is an active process and it is the responsibility of the educator to provide the learners with appropriate learning activities for learning and development to take place. The study made use of programme evaluation as research methodology. Programme evaluation refers to a research goal instead of specific research methods, because various methods can be used which may be quantitative or qualitative in nature. The gathering of data was done through classroom observations by the researcher, informal interviews with participating educators, questionnaires, and semi-structured interviews with the educators at the four schools the researcher monitored intensively during the implementation process of the intervention programme. The gathering of data was an ongoing process and the researcher analysed and interpreted the learners’ work at the end of the implementation process. The researcher checked this analysis by means of the literature review, transcripts and field notes. This formed the basis on which conclusions and recommendations could be made. The conclusions confirmed the importance of early intervention and the efficacy of the problem centered approach within the numeracy classroom. It also confirmed the disadvantages of the training model that was used, that is the Cascade model. With this study it was possible to determine that a ten week intervention programme was too short a period to observe meaningful improvements in learners. Therefore further research should be done on addressing learners’ difficulties and to train and support educators to provide learning support to their learners.
De, Jager Leon. "Die ondersteuning van leerders uit hoe risiko-gemeenskappe in primere skole." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/49922.
Full textENGLISH ABSTRACT: There are learners in the South African education system that reside and live within highrisk situations. These high-risk situations impact on the family-, scholastic and community contexts and also the relationship variables existing between these systems. The risk situations in which these learners live, cause and/or on occasion lead to early school exiting, teenage pregnancy, alcohol and substance abuse, the choice of living on the streets, youth misbehaviour and gangsterism. It is therefore important to determine and recognize the environmental contexts in which these learners find themselves to on the one hand reach a better understanding of this phenomenon, and on the other hand to organise effective aid and assistance initiatives. The following can be reported in this regard: Inconclusive evidence exists with respect to the exact nature of the problems, which confront primary school learners from high-risk situations. A shortage of effective strategies exists to support primary school learners from high-risk situations. This research is undertaken from a social constructionist, contextual ecosystemic perspective. The research is founded on a combination of both qualitative and quantitative methodological approaches and is undertaken within the interpretive research paradigm. An encompassing literature review was undertaken during which the following aspects were described and determined, namely: The problems encountered by learners from high risk situations. Recommendations from South African state departments regarding the assistance and support for learners from high-risk situations. Guidelines collected from the literature regarding the assistance and support for learners from high-risk situations. The empirical investigation is aimed at identifying the nature and extent of the prominent problems being experienced by learners from high-risk situations. Guidelines were developed by which learners from high-risk situations can be assisted and supported. These guidelines were developed on the basis of the research results yielded by the empirical investigation and a synthesis derived from literature exploration and the integration of empirical findings. The research focuses on Grade Seven learners from ten selected primary schools in the Boland region. The investigative instruments used during this research were the questionnaire, photo analysis and the focus interview. The research findings have shown that learners are more inclined to leave the school prematurely because of insufficient relationships that exists between the family, the community and the school. An integrated approach between these contexts is therefore essential to develop strategies in order to prevent learners from dropping out of school.
AFRIKAANSE OPSOMMING: Daar is leerders in die Suid-Afrikaanse onderwyssisteem wat 10 hoë risikoomstandighede woon en leef Hierdie risiko-omstandighede het 'n impak op hulle gesins-, skolastiese en gemeenskapskontekste asook die verhoudingsveranderlikes wat daar tussen hierdie sisteme bestaan. Die risiko-omstandighede waarin hierdie leerders leef, veroorsaak en/of lei soms tot byvoorbeeld voortydige skoolverlating, tienerswangerskappe, drank- en dwelmmisbruik, die keuse van 'n lewe op straat, jeugwangedrag en bendevorming. Dit is van belang om die omgewingskontekste van hierdie leerders te begryp en te verreken om enersyds tot 'n beter begrip van die fenomeen te kom, maar om andersyds effektiewe hulpverleningsinisiatiewe te ontwikkel. Die volgende kan in hierdie verband gemeld word: daar bestaan onvoldoende inligting ten opsigte van die wesenlike aard van die probleme wat leerders uit hoë risiko-omstandighede aan primêre skole ervaar; daar is 'n gebrek aan effektiewe strategieë om leerders uit hoë risiko-omstandighede aan primêre skole te ondersteun. Hierdie navorsing word onderneem vanuit 'n sosiaal-konstruksionisties, kontekstueelekosistemiese perspektief Die navorsing steun op 'n kombinasie van beide kwantitatiewe en kwalitatiewe metodologiese benaderings en word onderneem vanuit die interpreterende navorsingsparadigma. 'n Omvattende literatuurstudie is onderneem waartydens die volgende aspekte beskryfen beredeneer is: die probleme wat leerders uit hoë risiko-omstandighede ervaar. aanbevelings uit staatsdepartemente in Suid-Afrika oor die ondersteuning van leerders uit hoë risiko-omstandighede. riglyne vanuit die literatuur oor die ondersteuning van leerders uit hoë risikoomstandighede. Die empiriese ondersoek is daarop gemik om die aard en omvang van die prominente probleme wat leerders uit hoë risiko-omstandighede aan primêre skole ervaar te identifiseer. Riglyne waardeur hierdie leerders ondersteun kan word, is ontwikkel. Hierdie riglyne is ontwikkelop grond van die navorsingsresultate van die empiriese ondersoek en 'n sintese vanuit die literatuurverkenning en die integrasie van die empiriese bevindings. Die navorsing fokus op graad sewe-leerders aan tien geselekteerde primêre skole in die Boland-streek. Drie ondersoekinstrumente word tydens hierdie navorsing gebruik, naamlik die vraelys, foto-analise en die fokus-onderhoud. Die navorsingsresultate het getoon dat leerders meer geneig is om die skool voortydig te verlaat as gevolg van gebrekkige verhoudinge tussen die gesin, die gemeenskap en die skool. 'n Geïntegreerde benadering tussen hierdie kontekste is daarom belangrik om strategieë te ontwikkel wat sal verhoed dat leerders die skool voortydig verlaat.
Nel, Gerrit Oosthuizen. "Kooperatiewe leer as 'n aspek van kleingroepwerk in die primere skool." Thesis, Stellenbosch : Stellenbosch University, 1990. http://hdl.handle.net/10019.1/67300.
Full textENGLISH ABSTRACT: Small group work is a complex educational method which requires of the teacher not only a thorough knowledge of group work methods and group dynamic processes, but also thorough advance planning and organising before its implementation. Before the teacher implements small group 'Work in his class-room, he should formulate clear aims and objectives to serve as guideline for group activities. During small group work distinctive activities are undertaken and to increase the success of these activities, the teacher will have to create a positive climate which promotes the teaching and learning process. As with the creation of climate, the composition of the group is a variable which can be controlled by the teacher. The correct group composition will not only lead to more effective group functioning, but will also contribute to a healthy esprit de corps. Small group work implies a dramatic shift in emphasis in respect of the traditional roles of teacher and pupil. The role of the pupil (learner) changes from that of a passive listener to that of an active participant and discussion partner in the teaching and learning process. The role of the teacher who has been regarded as almost the only source and transmitter of knowledge, changes to that of a facilitator who leads and motivates the pupil to become an enquirer-learner. To be able to participate effectively in small group activities requires certain skills of pupils. Two skills, namely communication and problemsolving, which should be taught to the pupils purposefully and in a structured way, are described in this study. The success of small group work is to a large extent determined by these two skills. Co-operative learning is an educational technique which involves the pupil in becoming co-responsible for his own teaching and lea~ning process. Cooperative learning is described as an aspect of small group work where heterogeneous groups of approximately five members each, function interdependently of one another in order to attain a group aim. Co-operative learning techniques are aimed at eliminating, to a large extent, the passivity and isolation which may occur during ordinary group w0rk, as each group member is actively involved in the learning process. Co-operative learning techniques is also aimed at developing the pupil as a whole because components such as communication development, problem solving, socialising, conflict handling and leadership development are all involved. In this way the pupil may be better prepared to take his place in a complex society which is constantly making higher demands. The application of co-operative learning techniques in small group context may also offer a solution to the problems of combined and ever growing classes at present experienced in education.
AFRIKAANSE OPSOMMING: Kleingroepwerk is 'n komplekse onderrigmetode wat vereis dat die leerkrag nie aIleen oor deeglike kennis van groepwerkmetodes en groepdinamiese prosesse moet beskik nie, maar ook deeglik moet beplan en organiseer voordat dit gelmplementeer kan word. Voordat die leerkrag kleingroepwerk in sy klaskamer implementeer, moet hy eers duidelike doelstellings en doelwitte formuleer wat groepaktiwiteite kan rig. Tydens kleingroepwerk word eiesoortige aktiwiteite beoefen en om die sukses van hierdie aktiwiteite te verhoog, word die leerkrag genoop om 'n aangename positiewe klimaat te skep wat bevorderlik is vir die onderrig en leerproses. Soos klimaatskepping is groepsamestelling 'n veranderlike wat deur die leerkrag beheer kan word. Die korrekte groepsamestelling lei nie aIleen tot meer effektiewe groepfunksionering nie, maar kan ook bydra tot 'n gesonde groepgees. Kleingroepwerk impliseer 'n dramatiese klemverskuiwing ten opsigte van die tradisionele rolle van leerkrag en leerling. Die rol van die leerling (leerder) verander vanaf passiewe luisteraar na aktiewe deelnemer en medegespreksvennoot in die onderrig-en-leerproses. Die leerkrag wat feitlik as die enigste kennisbron en kennisoordraer beskou word, se rol verander nou na fasiliteerder wat eerder die leerling lei en motiveer om ondersoekendlerend op te tree. Om effektief aan kleingroepaktiwiteite deel te neem, vereis dat leerlinge oor sekere vaardighede moet beskik. In hierdie studie word twee vaardighede, naamlik kommunikasie en probleemoplossing beskryf wat doelbewus en gestruktureerd aan leerlinge geleer en ingeoefen moet word. Die sukses van kleingroepwerk word in 'n groot mate deur hierdie twee vaardighede bepaal. Kooperatiewe leer is 'n onderrigtegniek wat die leerling betrek om mede-verantwoordelikheid vir sy eie onderrig-en-leerproses te aanvaar. Kooperatiewe leer word beskryf as 'n aspek van kleingroepwerk waar heterogene groepe van ongeveer vyf lede elk interafhanklik van mekaar funksioneer ten einde dip. groepdoel te bereik. Kooperatiewe Ieertegnieke is oaaro: gemik om passiwiteit en isolasie w,at tydens gewone groepwerk mag voorkom in 'n groot mate te elimineer aangesien elke groeplid aktief by die leerproses betrek word. Kooperatiewe leertegnieke het ook ten doel om die leerling in sy totaliteit te laat ontwikkel aangesien komponente soos kommunikasie-ontwikkeling, probleemoplossing, sosialisering, konflikhantering en leierskapontwikkeling ter sprake kom. Sodoende kan die leerling beter voorberei word om sy plek in 'n komplekse samelewing wat steeds hoer eise stel, vol te staan. Die toepassing van kooperatiewe leertegnieke binne kleingroepverband bied ook moontlik 'n oplossing vir probleme van gekombineerde en groterwordende klasse wat tans in die onderwys ervaar word.
Stellenbosch University
Swanepoel, Geertje. "Voorbereiding van die pre-primere kind op hospitalisasie 'n Spelterapeutiese benadering /." Pretoria : [s.n.], 2004. http://upetd.up.ac.za/thesis/available/etd-10082004-072158.
Full textBayliss, William Henry. "'n Evaluering van tugmaatreëls in die Transvaalse primere skole / William Henry Bayliss." Thesis, Potchefstroom University for Christian Higher Education, 1991. http://hdl.handle.net/10394/9328.
Full textSkripsie (MEd)--PU vir CHO, 1992
Martins, Eder Marinho. "Obtenção do primeiro autovalor do p-Laplaciano via método das potências inverso." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/EABA-7Y6QE5.
Full textO principal objetivo desta tese é apresentar um novo método para o cálculo do primeiro autovalor para o p-Laplaciano, com condições homogêneas de Dirichlet na fronteira, inspirado no método das potências inverso de álgebra linear finita. Mostramos que o método é válido para qualquer bola em RN, se p > 1, e para qualquer domínio limitado no caso especial p = 2. Para p > 2, o método é validado numericamente para o quadrado e conjecturamos que o método seja válido para uma certa classe de domínios. Também utilizamos o método para calcular a função seno generalizada introduzida por Lindqvist.
Alvebratt, Marie-Louise, and Malin Jaginder. "Icke-farmakologiska interventioner vid behandling av primär hypertoni : ur ett omvårdnadsperspektiv." Thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-22845.
Full textBendrik, Sanna, and Mari Falck. "Effekter av fysisk aktivitet vid primär depression hos vuxna : En systematisk litteraturstudie." Thesis, Högskolan i Gävle, Avdelningen för vårdvetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-36043.
Full textBackground: People with mental illness, including depression, are an increasing public health problem that is usually treated with antidepressants and various forms of therapy in primary care. Physical activity can be offered as a treatment for depression and district nurses need knowledge of physical activity and its use as disease prevention and treatment in order to offer personalised, evidence-based care to people with depressive symptoms. Aim: The aim of this literature review was to describe the effect of physical activity on primary depression in adults, as well as to investigate whether the type, intensity, dose (frequency) or duration of physical activity had any impact on the effect. Method: Systematic literature review with narrative synthesis, including experimental, randomized controlled trials (RCT). Main results: Most of the studies’ interventions were performed in instructor-led groups and the results showed significantly reduced rates of depression in the majority of participants who participated in the interventions. All physical activity, regardless of type, intensity and dose (frequency), had an effect on depressive symptoms. However, the duration was seen to have an impact on the effect of physical activity on primary depression and interventions that lasted for a longer period of time gave more beneficial significant results. Coclusion: All physical activity, regardless of type, intensity and dose (frequency) had an effect on depression. The duration of the interventions had an impact on the effect, and interventions that lasted for a longer period of time had a greater effect on depression. These results can be useful in the district nurse’s clinical work when personalizing physical activity in the treatment of depression, for example in the education of patients and when prescribing physical activity on prescription (FaR®).
Ali, Dholfoqar. "Vilken effekt har statiner vid primär- och sekundärprevention av hjärt- och kärlsjukdomar?" Thesis, Linnéuniversitetet, Institutionen för naturvetenskap, NV, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-12009.
Full textBackground: Lipid-lowering drugs, mostly statines, were dispensed during 2011 to 815 000 people from the pharmacies in Sweden. High cholesterol is a major risk factor for development of coronary heart disease (myocardial infarction, angina, intermittent claudicatio intermittens and stroke). Coronary heart disease is the causes of more than 40% of all deaths in Sweden.Lifestyle changes, together with lipid-lowering drugs, statines, are effective treatments. Statines can be administered either to patients that have had a cardiac event i.e. heart attack, stroke (secondary care) or to persons with risk factors i.e. high levels of cholesterol, diabetes, primary care. Objective: with the help of published clinical trials and meta-analysis examine what effect statines have on morbidity / mortality in cardiovascular diseases in primary and secondary care. Results: The studies showed that statins reduce TC, LDL and TG and increase HDL. They also showed that statins reduce major coronary events, cerebrovascular events, mortality from coronary heart disease, unstable angina and revascularization. Statin therapy was associated with increased risk of moderate or severe liver failure, acute renal failure, moderate or severe myopathy and cataracts in both men and women. The risk was dose-dependent and greatest at the first year of treatment. Conclusion: The studies showed that statine treatment reduced the blood level of harmful cholesterol, prevented the atherosclerotic process and thus reduced the need for revascularization. Statin therapy is about two - three times as effective in secondary care as in primary care. One need to treat 60 people, who have had a coronary heart event, during about 5 years to prevent one death and 180 people to prevent a nonfatal cardiovascular event. The effect is similar for men and women and for older and middle aged people. Life expectancy increases by two years. For patients who not have had a coronary heart event but have risk factors i.e. high cholesterol levels, diabetes, one need to treat two - three times as many to achieve the same results (120 patients to prevent one death and 330 to prevent one nonfatal cardiovascular event). The effects of treating healthy individuals with statines are low.Statines are well-established and safe drugs. One noteworthy side effect is myopathy, (rhablomyelos) which is quite unusual as reported from studies.One problem that exists in all prescribed preventive treatments is poor adherence to prescriptions.
Watson, Ruby. "Wat is die invloed van skoolkultuur op die rol-identifisering van onderwysers by 'n primere skool in die Wes-Kaap?" Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/17965.
Full textENGLISH ABSTRACT: The reseach in this study focusses on how teachers express the forming of a role-identity amid historically disadvantage circumstances. The lense used to highlight and understand the underlying relationship between role-identity and school culture, is school context. The focus is on the biography and professional training of respondents in order to determine how teachers mediate their professional roles. We must understand teachers within the boundaries of a socio-cultural context, their biography and professional training. These factors, which contribute to the forming of role-identity, can negatively affect the receiving and implementation of policy. The assumption made by this study, is that there is a gap between transformation policies and school culture, which has an influence on the role of the teacher. A better understanding of teacher circumstances can inspire a multi-dimensional approach to teaching. The result was that my thesis tried to generate empirical evidence to understand teachers in under-privilege schools more fully. Teachers develop their self-identity within the framework of experience and expectations about themselves and their teaching. The professional identity of teachers consists of being skilled in subject area, level of training, preparedness and formal qualifications. Respondents construct their one-dimensional professional identity within an under-privilege context. The school climate hinders the simultaneous execution of the three roles that I refer to in this study. Some of the hindrance factors are the manner in which the school accepts the lack of learning area knowledge, racism and the abuse of contact time. Poor management and lack of community control, tolerates the shortcomings and one-dimensional approach of teachers. The study makes use of a theoretical framework, supported by literature. I used qualitative indepth-investigation for the collection of data. I used semi-structured interviews as an instrument to answer the research question and to achieve the proposed outcomes. I achieved my main finding by using empirical-interpretive techniques. The finding was that personal socialisation and professional training, together with contextual factors influence the foundation of teacher identity. The base identity is the foundation upon which teachers formulate their role-identity. My research shows how the respondents position themselves in relation to the prescribed teacher roles. Their identity forming takes places within the context of under-privilege circumstances, moral diffusion and transformation in education. I describe the construction of their conceptual space of role-identity. I furthermore present analyses of how the respondents form their role-identity. I base the most important finding of this study on one-dimensionality. Each of the selected teachers expresses their professional mediation of their roles within the context of a specific exposed school culture. The study shows the complex variations of this one-dimensionality amongst the four teachers.
AFRIKAANSE OPSOMMING: Die navorsing in hierdie studie konsentreer op hoe onderwysers gestalte gee aan hulle identiteitsvorming te midde van histories benadeelde omstandighede. Skoolkonteks is die lens wat gebruik word om die onderliggende verwantskap tussen rol-identiteit en skoolkultuur te verstaan. Die fokus is op respondente se biografië en professionele opleiding ten einde vas te stel hoe hulle die voorgeskrewe onderwyserrolle medieër. Onderwysers moet verstaan word binne die grense van 'n sosio-kulturele konteks, hulle biografiese verhale en professionele opleiding. Hierdie faktore is bydraende aspekte wat 'n invloed het tydens die vorming van rol-identiteit, sowel as tydens die ontvang en implementering van beleide. Die aanname wat deur hierdie studie gemaak word, is dat daar 'n gaping tussen hervormingsbeleide en skoolkultuur bestaan wat die rol-identiteit van die onderwyser beїnvloed. 'n Beter begrip van onderwyser-omstandighede, kan 'n multi-dimensionele benadering tot onderwys inspireer. Gevolglik het my tesis gepoog om empiriese bewyse te genereer wat kan bydrae tot 'n vollediger begrip van onderwysers in minder-bevoorregte skole. Onderwysers ontwikkel 'n self-identiteit binne die raamwerk van ervarings en verwagtinge oor hulleself en hulle onderrig. Die professionele identiteit van die onderwyser bestaan uit vaardigheid op vakgebied, vlak van opleiding, voorbereiding en formele kwalifikasie. Binne die minder-bevoorregte konteks waarin hierdie respondente onderrig, konstrueer hulle 'n een-dimensionele professionele identiteit. Die skoolklimaat belemmer die gelyktydige uitvoering van veral die drie rolle waarna ek in hierdie studie verwys. Sommige van die belemmerende faktore waarna verwys word, is die skool se gelate aanvaarding van gebrek aan leerarea kennis, rasisme en die misbruik van onderrigtyd. Gebrekkige bestuur en gemeenskapsbeheer vergemaklik verder die onderwyser se tekortkominge en een-dimensionele benadering. My studie word onderskraag deur 'n teoretiese raamwerk wat met behulp van literatuurwerke saamgestel is. Die proses van data-insameling is met die hulp van 'n kwalitatiewe indiepte-ondersoek gedoen. Die semi-gestruktureerde onderhoude wat gevoer was, het gedien as instrument ter beantwoording van die navorsingsvraag ten einde die beoogde doelstellings te bereik. My kern bevindinge het ek verkry vanuit empiriese-interpretatiewe tegnieke. Hiervolgens is bevind dat persoonlike sosialisering en professionele opleiding tesame met kontekstuele faktore, 'n invloed het op die samestelling van die identiteitsbasis van die onderwyser. Hierdie identiteitsbasis vorm die grondslag waarop onderwysers hulle rol-identiteit formuleer. My navorsing wys hoe die onderwysers in my studie hulleself posisioneer in verhouding tot hulle voorgeskrewe onderwyserrolle. Hulle identiteitsvorming geskied binne die konteks van minder-bevoorregte omstandighede, morele diffusie en onderwys transformasie. Ek beskryf hierdie konstruksie as hulle konseptuele ruimte van rol-identiteitsvorming. Verder bied hierdie studie 'n analise van hoe respondente hulle rol-identiteit vorm. Die vernaamste bevinding van hierdie studie is dat die geselekteerde onderwysers elk op 'n een-dimensionele basis uiting gee aan 'n professionele medieëring van hulle rolle binne hierdie skool se kultuur. Die studie wys die komplekse variasies van een-dimensionaliteit onder die vier onderwysers.
Van, der Merwe Johanna Marié. "Volgehoue behandelingsgedrag van primêre gesondheidsdiens pasiënte in 'n voorheen benadeelde gemeenskap in die Wes-Kaap /." Link to the online version, 2005. http://hdl.handle.net/10019/282.
Full textBarbosa, Fabrício de Paula Farias. "Os Inteiros Gaussianos via Matrizes." Universidade Federal da Paraíba, 2015. http://tede.biblioteca.ufpb.br:8080/handle/tede/9321.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
Our study aims to present a special category of numbers, the Gaussian integers, their properties and operations, have an overview about these numbers, their history and emergence. We will also study Gaussian prime numbers, their properties and application in matrix language representation of 2 x 2 type.
Nosso estudo tem como objetivo apresentar uma categoria especial de números, os inteiros Gaussianos, suas propriedades e operações, ter uma visão geral sobre esses números, sua história e surgimento. Também estudaremos números primos Gaussianos, suas propriedades e aplicação com representação em linguagem matricial do tipo 2 x 2.
Vermeulen, Cornelis Franz. "Senior primere leerlinge se begrip van sekere algemene getaleienskappe, met besondere verwysing na die distributiewe eienskap." Thesis, Stellenbosch : Stellenbosch University, 1991. http://hdl.handle.net/10019.1/69396.
Full textAFRIKAANSE OPSOMMING: Getaleienskappe, waaronder die kommutatiewe, assosiatiewe en distributiewe eienskappe en algemene herrangskikkingsbeginsels, vorm die boustene van manipulatiewe algebra. Navorsing en waarneming het aan die lig gebring dat hoerskoolleerlinge manipulatiewe algebra nie na behore beheers nie, dit wil se hulle beskik nie oor voldoende beheersing ten opsigte van die aard, betekenis, funksionalteit en logika van algebraise manipulasies nie. Hulle is dus nie daarvan bewus dat algebraiese manipulasies op die getaleienskappe berus nie, enersyds omdat hulle nie tydens die kennismaking met manipulatiewe algebra genoegsaam in die geleentheid gestel is om algebra as veralgemeende rekenkunde te ervaar nie, en andersyds omdat die getaleienskappe, waaroor jong kinders intuitiewe kennis besit, nooit vir hulle geeksplisiteer is nie. Hierdie studie stel ondersoek in na senior primere (hoofsaaklik standerd 3) leerlinge se vlak van bewustheid van enkele getaleienskappe, en benut enkele aktiwiteite om leerlinge na 'n hoer vlak van bewustheid daarvan te probeer lei. Hierbenewens word probeer om vas te stel of daar by leerlinge wat die eksperimentele primere wiskunde-kurrikulum volg (projekleerlinge) 'n hoer vlak van bewustheid aanwesig is as by leerlinge wat die tradisionele kurrikulum volg (nie-projekleerlinge). As· deel van laasgenoemde poging, word twee ondersoekmetod~s gevolg ten opsigte van spesifiek die distributiewe eienskap, naamlik kliniese onderhoude en vraelyste. Dit dien ook as deel van 'n breer poging om 'n meetinstrument te ontwerp waarmee moontlike verskille tussen die leeruitkomste van projek- en nie-projekleerlinge gemeet kan word. Dit wil uit die bevindinge van hierdie studie voorkom asof die oorgrote meerderheid leertinge eksplisiet bewus is van die kommutatiewe eienskappe ten opsigte van optelling en vermenigvuldiging en die algemene herrangskikkingsbeginsels, in 'n mindere mate ten opsigte van die minusteken voor hakies, en dat daar nie 'n noemenswaardige verskil in die vlak van bewustheid oor hierdie eienskappe by projek- en nie-projekleerlinge bestaan nie. Sover dit die distributiewe eienskap betref, lyk dit asof daar 'n redelike verskil in die vlak van bewustheid by projek- en nie-projekleerlinge is met eersgenoemde die hoogste. Tog word die mening uitgespreek dat die vlak van bewustheid by projekleerlinge nie hoog genoeg is nie, en dat hulle in minstens standerd 4 en 5 in die geleentheid gestel moet word om hierdie getaleienskap vir hulself te eksplisiteer.
Alm, Charlotte, and Åsa Tornell. "Medveten närvaro och beteendeterapi vid behandling av primär insomni : Effekter på sömn, uppmärksamhet, oro och ruminering." Thesis, Örebro universitet, Akademin för juridik, psykologi och socialt arbete, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-15811.
Full textPeople with insomnia attend to sleep-related stimuli during the day and night. The activity is called monitoring. In mindfulness (MN) attention plays a central part, and by practicing MN the ability to direct attention can be improved. The aim of this study was to explore the effect of MN and behavioral therapy (BT) when treating people with primary insomnia who tend to monitor sleep-related cues. The effect on sleep and monitoring was examined, as well as the secondary effect on worry and rumination. A single-subject design with a constructive strategy was used. Two different treatments were implemented and half of the participants were given BT and the other half BT+MN. Together the results showed that sleep, monitoring and worry improved, but independent of MN. A suggestion for future research is to extend the current design to further explore the effect of MN within the treatment of insomnia.
Kouassi, Evrard Gaubys. "L'analyse structurelle de la prime dans le contrat d'assurance." Thesis, Toulouse 1, 2017. http://www.theses.fr/2017TOU10001.
Full textThe insurance contract occupies now more than ever, a predominant place in our lives. This insurance culture fits into the smallest acts of our lives. As a matter of fact, it is becoming very difficult to deal without an insurance contract in this ultra-secure world toward which we are heading. Indeed, the question of insurance is gradually developing in almost all areas of our existence: from unpaid rent to the lease giver, to the loss of luggage, files, credit cards; from health matters to trip cancellation etc. Insurance is so implanted in our daily lives that paying an insurance premium to shield from a feared event seem to be the norm. We pay the premium without necessarily worrying about its real issues and consequences in the contractual mechanism; its role in the contractual relationship between the policyholder and the insurer. As we may recall, there have been many written theories in insurance law, but very few are those who are interested in the insurance premium which is, however, an essential element, if not an indispensable one in the insurance contract. Thus, the objective of this thesis is to position the insurance premium in the heart of the contractual mechanism, to bestow somehow its true nobility
Lassas, Anna. ""LIA eller morfin spinalt vid primär total höftplastik". : en långtidsuppföljning av effekter för postoperativ smärta och mobilisering." Thesis, University of Gävle, University of Gävle, Department of Caring Sciences and Sociology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-5182.
Full textVid operation av primär total höftplastik finns det olika metoder för postoperativ smärtlindring. En tidigare genomförd studie på ett mellansvenskt sjukhus (nedan kallad ”höftprojektet”) visade att ”Local infiltration analgesia” (LIA) initialt minskade postoperativ smärta, underlättade mobilisering samt förkortade vårdtiden, jämfört med spinalt morfin. I denna studie genomfördes en långtidsuppföljning av höftprojektet med mätningar efter 6 respektive 12 veckor. Studiegruppen hade fått LIA vid operationsslutet och kontrollgruppen spinalt morfin. Båda grupperna hade en spinal bedövning under operationen. Denna långtidsuppföljning genomfördes med hjälp av journalgranskning och hade en deskriptiv och jämförande design med en kvantitativ ansats. Studiegruppen bestod av 40 patienter och kontrollgruppen 11 patienter. Studerade variabler var smärta mätt genom Visuell Analog Skala (VAS), behov av analgetika och mobilisering. Resultatet visade att det inte fanns någon signifikant skillnad mellan de båda grupperna när det gäller mobilisering under ett längre perspektiv. Det fanns dock en signifikant skillnad när det gäller smärta efter 3 månader, då studiegruppen uppgav en lägre grad av smärta än kontrollgruppen.
There are several methods for postoperative pain treatment after primary total hip replacement. It was shown in a earlier study at a Swedish hospital (below named as "the hip project") that "Local infiltration analgesia" (LIA) decreased pain, facilitated early postoperative mobility and earlier discharge from the hospital, compared with spinally administered morphine. Present study is a long term follow up of the hip project with two measures at 6 and 12 weeks. The study group was given LIA towards the end of the operation while the control group were given spinal morphine at the induction. Both groups had spinal analgesia during the surgery. The long term follow up was conducted by a comparative design and the data was collected from the patient’s charts and files. The variables were pain measured by Visual Analogous Scale (VAS), need of pain relieves and general mobility. The study group contained of 40 patients and the control group of 11. The result relived no significant differences between the two groups regarding long term mobility. There was, however, a significant difference in pain after 12 weeks; the study group had less pain that the control group.
Mustafa, Lorin. "Är kombinationsbehandling med levotyroxin och liotyronin ett bättre alternativ än behandling med enbart levotyroxin vid primär hypotyreos?" Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-95812.
Full textLujan, Maria Lucia S. "A geometria da 1a serie do 1o grau : um trabalho na perspectiva de Van Hiele." [s.n.], 1997. http://repositorio.unicamp.br/jspui/handle/REPOSIP/253329.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação
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Resumo: Esta pesquisa teve como fundamento o modelo de desenvolvimento do pensamento geométrico de van Hiele e apoiou-se na Psicologia Genética de Piaget. Foram investigadas algumas atividades geométricas em alunos em início de escolarização. Utilizou-se, para isso, materiais não industrializados e confeccionados especialmente para este trabalho. Foram sujeitos desta pesquisa 44 crianças da 12 série do 1 Q grau de uma escola da rede oficial do Estado de São Paulo, que constituíram o grupo experimental e o grupo de controle. Esses sujeitos foram submetidos ao pré-teste, intervenção pedagógica e pós-teste. Os resultados indicaram que os sujeitos do grupo experimental, e que foram submetidos a um trabalho de intervenção pedagógica, apresentaram um desempenho significativamente melhor no pós-teste que o grupo de controle que não participou do trabalho de intervenção pedagógica. A pesquisa mostrou, também, que alunos de 1º série, podem adquirir conceitos geométricos, como os estudados nesta pesquisa, se a proposta de trabalho pedagógico for condizente ao nível cognitivo dos educandos
Abstract: This research had as basis the geometric thought development model of van Hiele and was assisted by the Piaget's genetic psychology. A few geometrical activities of students in the elementary school were investigated. For this purpose non-industrialized materials were used and made specially for this work. For this research 44 children first graders (elementary school) from an official school of the São Paulo State formed the experimental and the control groups. Those students were submitted to an initial test, pedagogical intervention and a post test. The results indicated that the students from the experimental group, who were submitted to pedagogical intervention, presented a significantly better performance in the post test than the control group, who did not participate of the pedagogical intervention. This research has also shown that students of the first grade of the elementary school can acquire geometrical concepts, as those used in this work, only if the proposed pedagogical work was adequate for their cognitive level
Mestrado
Educação Matematica
Mestre em Educação
Terblanche, Hester Helena. "Die belewenisse en sosio-emosionele behoeftes van familielede as primere VIGS-versorgers binne 'n ekologiese perspektief : 'n kwalitatiewe studie." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/95929.
Full textENGLISH ABSTRACT: Due to a lack of research, which, in turn, resulted in a shortage of applicable literature that focused on the experiences and socio-emotional needs of family members as carers of AIDS-patients, the researcher decided to undertake this research project. The aim of this was to investigate the experiences and socio-emotional needs of family members as AIDS care givers. To lead the research, the researcher made use of a qualitative research approach. Attention was also given to the description of HIV/AIDS, as well as the prevention and treatment of HIV/AIDS. The impact of HIV/AIDS was also given attention, and it was done from an ecological perspective. Within the qualitative research paradigm a phenomenological, explorative, descriptive and contextual research design was utilised. The boundaries for data collection were delineated to the George area. Semi-structured interviews were conducted with family members who acted as primary care givers of AIDS-patients who were recruited by means of purposive sampling and the snowball sampling technique. The data collected were analysed according to the steps for qualitative data analysis as proposed by Tesch (in Cresswell, 1994). To ensure the trustworthiness of the research findings, data verification was executed according to Guba’s model (in Krefting, 1991). The following twelve themes emanated from the process of data analysis: - Knowledge of the disease - Caring for people with AIDS - Risky behaviour - Other people’s reactions - Care givers’ feelings and reactions - Support that was received with the care giving - Effect of the care giving on the relationship between the care giver and the patient - Changes in the care givers’ life because of the care giving of AIDS patients - Experiences regarding the dying process - Needs regarding the caring of the patient - Services that are needed - Advice from the participants to other family members as AIDS care givers. The following recommendations were made based on the conclusions derived from the research findings: Information sessions by Social Workers in collaboration with the different clinics on certain days; a community based project to recruit volunteers to support family care givers on a regular basis; look at facilities, like old age homes and hospices, that can give respite for a week to three weeks; connect family care givers to support groups in the community; make use of the media to give information regarding HIV/AIDS to the broader community; a centralized food and clothes bank from which care givers can draw affordable food and clothes. An application for funding can be done at the Department of Social Development or the Department of Health. Another recommendation that is made is to investigate the possibility of a community based project that provides cleaning and washing services to family members as care givers, as well as the patients. This can even become a job creation project. Other recommendations are: to investigate an alternative form of transport that is wheelchair accessible and patient friendly; to train home based carers to help family members as AIDS care givers; to train home based carers to be of assistance with counseling of patients with regard to their medication; to train home based carers as AIDS care givers to help family members to reach out to other support services or groups; that care givers should be careful about expectations of other people and that they should be confident enough to verbalize their expectations; that Social Workers should investigate if the family member, as AIDS care giver, as well as the patient, gets the necessary support on all levels of the ecological perspective, and if not, he/she must look at ancillary sources and mobilize it to give support to the family care giver as well as to the patient; that professionals need to keep in mind the advice the participants was given to other family members as care givers when they are working with these families. A recommendation was also made to do a follow-up research on the same topic in the White, Indian and Black communities and especially that further emphasis should be placed on their needs, as participation by this population groups were scarce or could not be obtained at all.
AFRIKAANSE OPSOMMING: Weens ‘n gebrek aan navorsing, en gevolglik ook aan literatuur rakende die belewenisse en sosio-emosionele behoeftes van familielede as primêre VIGS-versorgers, het die navorser besluit om hierdie navorsingsprojek te onderneem. Die doel hiermee was om die belewenisse en sosio-emosionele behoeftes van familielede as primêre VIGS-versorgers te verken en te beskryf. Om die navorsing te rig, is ‘n kwalitatiewe navorsingsbenadering vir die doel gebruik. Aandag is ook gegee aan die beskrywing en voorkoms van MIV/VIGS, asook die voorkoming en behandeling van MIV/VIGS. Die impak van MIV/VIGS is ook breedvoerig bespreek en is dit vanuit ‘n ekologiese perspektief gedoen. Binne die kwalitatiewe navorsingsbenadering is daar van ‘n fenomenologiese, verkennende, beskrywende en kontekstuele navorsingsontwerp gebruik gemaak. Die grense vir data-insameling het binne die George-area geval. Semi-gestruktureerde onderhoude is gevoer met familielede wat as primêre VIGS-versorgers optree, en wat deur middel van ‘n doelgerigte steekproeftrekking en die sneeubaltegniek vir deelname aan die navorsing gewerf is. Die ingesamelde data is ontleed aan die hand van die agt stappe van kwalitatiewe data-ontleding van Tesch soos uiteengesit in Creswell (1994). Guba se model soos dit in Krefting (1991:214-221) uiteengesit is, is gebruik om die vertrouenswaardigheid van die navorsingsdata te verifieer. Twaalf temas het na aanleiding van die prosesse van data-ontleding na vore gekom, naamlik: - Kennis van die siektetoestand - Versorging van VIGS-lyers - Risiko-gedrag - Ander mense se reaksie - Versorger se gevoelens en reaksies - Ondersteuning wat ontvang is met die versorging - Effek van pasiënt se versorging op die verhouding tussen versorger en pasiënt - Verandering van versorger se lewe as gevolg van die versorging van die VIGS-lyer - Belewenisse ten op sigte van die sterwensproses - Behoeftes ten opsigte van die versorging van die pasiënt - Dienste wat benodig word - Raad deur deelnemers aan ander familielede as VIGS-versorgers. Voortspruitend uit die navorsingsbevindinge, is tot sekere gevolgtrekkings gekom waaruit die volgende aanbevelings gemaak is: dat inligtingsessies deur maatskaplike werkers in samewerking met die verskillende klinieke op sekere dae gehou sal word; dat ‘n gemeenskapsprojek van stapel gestuur word om vrywilligers te werf wat op ‘n gereelde basis aan VIGS-versorgers ondersteuning bied; dat daar gekyk word na respite by ouetehuise of ‘n hospice vir ‘n tydperk van ongeveer drie weke om aan versorgers ‘n ruskans te gee; dat versorgers betrek word by ondersteuningsgroepe in die gemeenskap; dat die media gebruik word om inligting oor VIGS aan die breë gemeenskap deur te gee; dat aandag gegee word aan ‘n gesentraliseerde voedsel- en klerebank waarvandaan versorgers voorraad kan onttrek. Aansoek vir befondsing kan gedoen word by Departement Maatskaplike Ontwikkeling of Departement Gesondheid. Verdere aanbevelings wat gemaak kan word, is: dat ‘n gemeenskapsprojek van stapel gestuur word om skoonmaakdienste en hulp met wasgoed was tot die beskikking van die VIGS-versorger te stel wat selfs as ‘n werkskeppingsprojek begin kan word; dat ‘n alternatiewe vorm van vervoer wat deur die familielid en pasiënt benut kan word, en wat geskik is vir pasiënt vervoer, ondersoek sal word; dat opleiding van tuisversorgers as hulp vir familielede as VIGS-versorgers aandag sal kry; dat opleiding van tuisversorgers om behulpsaam te wees met berading van pasiënte rakende hulle medikasie dringende aandag sal geniet; dat familielede as VIGS-versorgers uitreik na ander ondersteuningsbronne vir hulp; dat versorgers versigtig sal wees ten opsigte van verwagtinge van ander, maar dat hulle ook vrymoedigheid sal neem om hulle verwagtinge te verbaliseer; dat die maatskaplike werker sal ondersoek instel of die familielid as primêre VIGS-versorger, sowel as die pasiënt, vanuit al die vlakke van die ekologiese perspektief die nodige ondersteuning geniet, en indien nie, moet daar gekyk word na hulpbronne en dit moet gemobiliseer word ten einde hierdie noodsaaklike ondersteuning te bied; dat die raad wat deur die deelnemers aan die navorsing aan ander familielede as VIGS-versorgers voorsien is, in gedagte gehou sal word wanneer met hierdie families gewerk word. ‘n Aanbeveling is ook gemaak dat opvolg navorsing oor dieselfde onderwerp gedoen word onder die Wit, Indiër en Swart gemeenskappe, en dat veral klem gelê word op hulle behoeftes, aangesien deelname vanuit hierdie bevolkingsgroepe skraal was, of glad nie bekom kon word nie.
Jara, Pereda Luz María. "Niveles de razonamiento según el modelo de Van Hiele que alcanzan los estudiantes del primer año de secundaria al abordar actividades sobre paralelogramos." Master's thesis, Pontificia Universidad Católica del Perú, 2015. http://tesis.pucp.edu.pe/repositorio/handle/123456789/6611.
Full textTesis
Nieto, Espinet Ariadna. "Entre el consum i l'afecte. La interacció entre els animals i les comunitats protohistòriques de la plana occidental catalana (segles VII - IV a.C)." Doctoral thesis, Universitat de Lleida, 2012. http://hdl.handle.net/10803/96488.
Full textLa disciplina arqueofaunística ha permitido extraer diversos datos a partir del estudio de los restos oseos animales procedentes de diversos yacimientos protohistóricos de la plana occidental catalana. La gestión de los resultados a comportado la caracterización de: los modelos de producción ganadera de las especies domésticas; los patrones de en las actividades cinegéticas; los patrones de consumo alimentario de base animal; y las practicas de carácter no subsistencial, poniendo un especial énfasis en los conjuntos procedentes de la fortalesa dels Vilars (Arbeca, les Garrigues). Aun que este yacimiento haya proporcionado un corpus mas importante de datos, el presente estudio ha ofrecido una visión diacrónica a nivel espacial y cronológica. A través de su inclusión en un proyecto mucho mas amplio (HUM2006-06384: Las transformaciones sociales a través de los espacios de la vida y la muerte en el noroeste del Mediterráneo durante el III y I milenios ANE), centrado en el origen y formación de las sociedades complejas a la zona, los resultados han aportado nuevos datos e indicadores que han permitido perfilar y implementar el modelo de evolución socioeconómica propuesto para la zona de la plana occidental catalana, des el Bronce final hasta el ibérico Pleno.
The archaeozoological discipline has allowed to extract different data from the study of animal bone remains proceeding from different sites of the western plain of Catalonia. The treatement of the results made possible the characterization of : i) livestock production models of domestic species, ii) the patterns of hunting activities, iii) the patterns of meat supplying and consumption, iv) non-subsistence practices, with special emphasis on the sets from the Fortress dels Vilars (Arbeca, Garrigues). Although this site has provided a most important corpus of data, this study has offered a diachronic spatial and chronological perspective. Taking part of a much broader project ((HUM2006-06384: Las transformaciones sociales a través de los espacios de la vida y la muerte en el noroeste del Mediterráneo durante el III y I milenios ANE) focused on the origin and formation of complex societies in the area, the results provided new data and evidence that have precised and completed the socio-economic development pattern proposed for the western plain of Catalonia, from the Bronze Age to the Iberian Period.
Van, der Lith Sarel Petrus. "'n Prinsipiële ondersoek na ouerbetrokkenheid op mikro-onderwysvlak in die blanke primere skool in Suid-Afrika / Sarel Petrus van der Lith." Thesis, Potchefstroom University for Christian Higher Education, 1991. http://hdl.handle.net/10394/8385.
Full textThesis (MEd)--PU vir CHO, 1992
Popeijus, Herman Leendert. "Het onderwijsaanbod, van wet tot keuze een onderzoek naar het beslissingsproces voor de keuze van een onderwijsaanbod voor begrijpend lezen op scholen in het primair onderwijs in Nederland en Vlaanderen /." Nijmegen : Popeijus, 2003. http://doc.utwente.nl/55979.
Full textÖstblom, Desirée, and Emma Sjölander. "Kartläggning av och skillnader i postoperativa restriktioner vid primär total höftplastik utfört med direktlateralt snitt hos utförande sjukhus i Sverige." Thesis, Uppsala universitet, Fysioterapi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-351793.
Full textBackground: Total hip arthroplasty (THA) is commonly performed on patients with hip osteoarthritis when conservative treatment no longer reliefs pain sufficiently. Movement restrictions are applied to prevent hip dislocations, although those have recently been questioned since studies have shown that a liberal regimen does not increase the risk of hip dislocation. Purpose: To chart movement restrictions following THA performed with a direct lateral approach at Swedish hospitals and analyzes differences in those between university hospital, county hospitals, district hospitals and private hospitals. This study also aimed to chart non- standardized movement restrictions. Method: A cross-sectional study with a descriptive and comparative design. Data was collected from a self-made web survey, which was answered by 42 hospitals. Results: The appliance of restrictions regarding flexion beyond 90°, external rotation beyond 45°, internal rotation beyond 45°, adduction beyond centerline and flexion of 90° or beyond combined with adduction and rotation varied among the participating hospitals. There were no significant differences between participating hospital groups regarding mentioned movements. Non-standardized restrictions were influenced by the individual factors of the patient as well as the prosthesis type. Patients were also recommended to not perform any extreme movements. Conclusion: There is a variation regarding appliance of postoperative restrictions during the first six weeks postoperatively. In the light of the results of this study, together with recent evidence postoperative, restrictions should be further discussed.
Nilsson, Susanne, and Madeleine Rydin. "Patientens hälsokompetens kring risken att utveckla kardiovaskulär sjukdom vid ohälsosam livsstil och primär hypertoni : en enkätstudie av patienter i primärvården." Thesis, Sophiahemmet Högskola, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-2954.
Full textApproximately 2 million people in Sweden are diagnosed with hypertension, which is a public health disease that is estimated to cause 30, 000 cases of stroke and myocardial infarction every year. An overall growing and aging population in the world is the cause of the increase in the numbers of people diagnosed with hypertension in the world. Hypertension is caused by functional changes in the arterial wall which causes a stiffness in the vessel. This stiffness is a result of factors such as dyslipidemia, smoking, diabetes, age, consumption of alcohol and other lifestyle factors. People with hypertension have an increased risk of developing cardiovascular diseases such as stroke, heart failure, coronary arterial disease and kidney disease. Hypertension is also the greatest treatable risk factor for cardiovascular disease. Lifestyle changes is the cornerstone in the treatment of hypertension, however many individuals may also need drug therapy. For the individual to achieve lifestyle changes, the patient needs a high level of health literacy and a person centred approach from health care professionals are needed Aim: The aim of this study was to investigate the patient’s health literacy relating to the risk of developing cardiovascular disease with an unhealthy lifestyle in combination with essential hypertension. A question formulation was constructed as a compliment to the aim of the study with the purpose of identifying possible differences between the sexes. Method: The method was an empirical descriptive non experimental cross-sectional study with a quantitative approach. The authors choose to conduct the study by handing out 50 questionnaires to patients diagnosed with essential hypertension between the years 2014-2017 at a public health office in southern part of Sweden. Result: Participants received information regarding lifestyle changes such as eating habits, smoking, alcohol consumption and physical activity and their importance when diagnosed with hypertension. The results also showed that the participants made changes regarding this. However not all participants got information or made changes and a differences between men and women could be seen. Conclusion: Making health care professionals conscious of the patient’s health literacy while maintaining a person centred approach in the primary preventive care, which is focusing on lifestyle changes, is of utmost importance. It is essential to enable the patient’s self care regarding their essential hypertension, which further reduces the risk to develop cardiovascular disease, promotes health and benefits the economy of the society.
Sghaier, Nadia. "Les cycles de souscription en assurance non vie : Étude de la dynamique du ratio combiné et des déterminants des primes." Paris 10, 2011. http://www.theses.fr/2011PA100046.
Full textDespite the considerable number of theoretical and empirical studies analyzing the underwriting cycles in non life insurance. No clear conclusion and only seems to highlight. The lack of consensus seemed to us arise from the lack of suitable linear modelling and forgetting the properties of cointegration applied both in the context time series and panel data. This thesis was then attached to review the underwriting cycles while focusing on the dynamics of the combined ratio and the determinants of premiums for the case of France and for other countries. In the first chapter, we presented a review of the literature on the subject. In the second chapter, we analyzed the underwriting cycle and the determinants of premiums for the aggregate sector in French using the econometrics of nonlinear time series. In the third chapter, we applied the recent developments in the econometrics of panel data taking into account the non stationary and the nonlinearity, firstly, to conduct a disaggregated analysis by French line of the underwriting cycle and the determinants of premiums and, secondly, to carry out a comparative analysis of the determinants of premiums in an international framework. The obtained results for the aggregated sector French led us to conclude that the cyclical phenomenon disappeared in France since 1989 and that the dynamics of the combined ratio is rather modelled by a smooth transition regression model (STR). The pricing of the premiums seems to change from 1985 and the rate of growth of premium appears to be represented by a smooth transition error correction model (STECM). Then the estimation of the static and the dynamic panels allowed us to detect similaritires in the dynamics of the combined ratios of the lines of the non life insurance. Similarly, the estimation of cointegration relations in panel data allowed us to identify differences in the determinants of the premiums lines of the non life insurance. Finally, the comparative analysis by country showed that the rate of growth of the premiums of the countries are reproduced by a panel smooth transition error correction panel data (PSTECM)
Karlsson, Molly. "En kombination av Ca2+-antagonister och ACE-hämmare ger en mer effektiv blodtryckssänkning i jämförelse med monoterapi vid primär hypertoni." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-96708.
Full textPérez, Martínez Meritxell. "Tarraco christiana. Cristianización y organización eclesiástica de una capital provincial romana (siglos III al VII)." Doctoral thesis, Universitat Rovira i Virgili, 2005. http://hdl.handle.net/10803/8638.
Full textAprofundir en el coneixement de la Tarraco christiana en els períodes tardorromà i visigòtic obliga a l'historiador a enfrontar-se a la tasca summament ingrata de reconstruir extenses llacunes documentals i etapes mancades d'un suport documental sòlid i continu. Per això, no és estrany que la Tarraco christiana hagi despertat certa perplexitat entre els qui al llarg de la història s'ha interessat per ella i, amb major o menor fortuna, han pretès resoldre les enormes contradiccions que poblen el seu discurs històric. L'interès dels últims anys per l'Antiguitat Tardana ha contribuït a la revalorització dels materials d'aquests segles i a la seva identificació cada cop més precisa per part dels especialistes. Però, malgrat la recent proliferació de monografies, més o menys completes, i de la intensificació de les troballes, continuaven faltant estudis de síntesi actualitzats que proporcionessin una visió global de la història de la Tarraco christiana als segles de la transició a l'Edat Mitjana. El panorama actual ha estat capitalitzat durant molts anys per una certa tendència a la repetició de vells tòpics historiogràfics, que exigien ser revisats. Per altra banda, s'ha detectat una absència de perspectiva que impedia integrar la dinàmica històrica i arqueològica de la civitas tarraconense en els processos històrics d'abast general. La presència d'aquestes contradiccions feia necessària una nova monografia que dugués a terme una síntesi de l'estat actual dels coneixements, basada en una relectura sistemàtica de les fonts convencionals i l'adopció d'un mètode interdisciplinari rigorós, que contemplés la inclusió de les novetats de l'estudi arqueològic i del debat historiogràfic contemporani sobre els temes de transició, desenvolupat en àmbit europeu.
Després de l'estudi realitzar, la Tarraco christiana proporciona una òptima visió de conjunt que permet millorar el coneixement sobre la problemàtica de la transició a Hispania. Així mateix, contribueix a donar resposta a alguns dels interrogants fonamentals que planteja la Tarragona d'època tardana, amb les pròpies especifitats que li confereixen el caràcter de paradigma en la seva evolució. Més enllà de la significativa absència de notícies relatives a la construcció de l'església episcopal, la major part dels testimonis documentals i materials conservats procedeix del període d'auge creatiu i institucional que va embargar a la metròpolis eclesiàstica durant els gairebé dos-cents anys que separen els bisbats d'Himeri i Sergi de Tarragona (370-560). La història de la civitas ecclesiastica revela l'amplitud dels processos formatius relatius a la cristianització i la organització eclesiàstica de la capital provincial romana, a la vegada que confirma el protagonisme de dits processos en la dinàmica històrica de la ciutat dels segles de la transició a l'època medieval. Per altra banda, permet constatar un desenvolupament natural i pacífic, la característica principal del qual és el respecte i la continuïtat dels segles de la transició a l'època medieval. Per altra banda, permet constatar un desenvolupament natural i pacífic, la característica principal del qual és el respecte i la continuïtat dels quadres romans. En efecte, l'estudi de la Tarraco christiana durant els segles de l'Antiguitat Tardana evidencia una perduració i un predomini de l'element romà, que es fa palès mitjançant la perpetuació d'unes determinades formes de vida a la capital, així con en el manteniment d'un contacte continuat amb les ciutats del territori provincial Escriure la història de la Tarraco christiana a les èpoques tardorromana i visigòtica és quelcom ineludiblement lligat a la consideració del mar Mediterrani com espai històric. Fins el final del segle VII, aquest fou predominantment romà. Les etapes d'enfortiment del poder dels monarques visigots, que seguiren als regnats crucials de Leovigild i Recared, contribuïren al progressiu silenci del metropolità eclesiàstic i la seva església en el marc de la construcció d'una església visigoda centralitzada a Toledo. Si bé no implicaren una pèrdua del caràcter ciutadà, aquestes qüestions repercutiren en l'absència total o parcial de les fonts documentals i materials que permeten escriure la història de la Tarraco christiana als últims segles de la transició a l'Edat Mitjana.
The subject of this Ph. D. thesis is the study of Tarraco in the Late Roman and Visigothic periods, with an especial interest on the Christianisation and Ecclesiastical organisation of the Roman province capital. These matters are analysed diachronically describing the ruptures and continuities
Garfì, Marianna <1981>. "Tecnologie appropriate per la gestione delle georisorse nei paesi in via di sviluppo e nei paesi dell'America Latina. Creazione di una metodologia multi criteria per la valutazione dei progetti di sviluppo umano." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2009. http://amsdottorato.unibo.it/2105/.
Full textLjung, Sofia. ""Jag är inte ensam" : Patienternas upplevelse av livsstilsfokuserad gruppbehandling inriktad på primär och sekundär prevention vid hjärt-kärlsjukdom och typ 2 diabetes." Thesis, Umeå universitet, Institutionen för kostvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-46700.
Full textBackground Cardiovascular disease and type 2 diabetes is nowadays two of the most common welfare diseases although 80% of the morbidity of these diseases could be prevented through lifestyle changes. Changing lifestyle has proven to be difficult and support from professionals as well as from relatives have showed to be crucial in order to succeed. The physiological effects of lifestyle-focused treatment are relatively well studied but how patients actually experiencing such treatment is still rather unclear. Objective The aim of this study was to explore how patients experience lifestyle focused group-treatment as a primary and secondary prevention of cardiovascular disease and type 2 diabetes. Methods 19 qualitative interviews were conducted with patients at a day center in northern Sweden. A semi-structured interview guide was used but the main focus was on the patients' own stories about their experiences. The interviews were transcribed verbatim and then analyzed according to systematic text condensation. Results The lifestyle focused group-treatment was perceived as important in several ways. Among other things it appeared that patients felt that they were in great need of support, both from professionals and from other patients, and that it was a need that was met. It could also be observed that the understanding of the patients own responsibilities for their health grew over the course of treatment but that it unfortunately also could create a sense of shame and ambivalence towards treatment. The fact of being treated in groups was experienced as positive because it gave the patients the opportunity to exchange experiences and gave a sense of fellowship. Conclusions It's clear that lifestyle focused group-treatment serves several important functions for the patients in addition to the parameters that are physiologically measurable. These patients are in need of several different types of support, and both staff and patients are important to make the experience of the treatment satisfying, a conclusion which support the idea of group-treatment. Furthermore, this kind of treatment can strengthen the patients' insight about the own responsibility for the health which can be a important factor that have a mind as a therapist.
Cantelli, Elvis William Carvalho dos Santos. "Enriquecimento de elementos pesados no aglomerado globular do bojo NGC 6522: traços da primeira geração de estrelas." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/14/14131/tde-17102018-105902/.
Full textThere is a concentration of moderately metal-poor globular clusters in the Galactic bulge, and many of them show a Blue Horizontal Branch (BHB). These characteristics together point to an old age. In order to better understand the origin of these clusters, the study of their abundance pattern can help identifying the kind of the earliest supernovae in the central parts of the Galaxy. NGC 6522 in Baades Window is a representative of this class of clusters. Abundance analyses of individual stars in this clusters have confirmed its metallicity of [Fe/H]-1.0, enhanced -elements, and detected a variation in the abundances of the s-process heavy elements. Among the highest enhancements of Y and Ba, the usual explanation of mass transfer from a companion in the Asymptotic Giant Branch might not apply, and an enrichment by early fast-rotating massive stars was suggested. In order to further study the abundances in NGC 6522 we obtained a run with FLAMES- UVES in 2012, from which with the UVES data we have shown that the enhancement in s-elements could still be accommodated with the companion transfer model. We further obtained new data with FLAMES-UVES in 2016. In the present work we analyze another 6 stars observed at high resolution with UVES, and 32 stars at medium-high resolution observed with GIRAFFE. The latter were selected from their radial velocities of -14.3±15 km/s. The abundances of the light elements C, N, O, odd-Z elements Na, Al, -elements Mg, Si, Ca, Ti, iron-peak elements Mn, Cu, Zn, s-process elements Y, Zr, Ba, La, Ce, Nd and r-process element Eu are derived. Among the UVES stars, two of them show a significant enrichment in s-process elements and one of them show high [Y/Ba] and [Zr/Ba] ratios, suggesting that an early enrichment by fast rotating massive stars is a probable scenario.
Mastragostino, Giada. "Analisi del ciclo di vita della produzione industriale di acroleina: confronto tra il processo tradizionale e vie di sintesi alternative." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/6534/.
Full textNichil, Geoffrey. "Provisionnement en assurance non-vie pour des contrats à maturité longue et à prime unique : application à la réforme Solvabilité 2." Thesis, Université de Lorraine, 2014. http://www.theses.fr/2014LORR0200/document.
Full textWe consider an insurance company which has to indemnify a bank against losses related to a borrower defaulting on payments. Models normally used by insurers are collectives and do not allows to take into account the personal characteristics of borrowers. In a first part, we defined a model to evaluate potential future default amounts (provision) over a fixed period.The amount of default is the key to our model. For a borrower j and an associated maturity Tj, this amount is max(Sj Tj -Rj Tj ; 0), where Sj Tj is the outstanding amount owed by the borrower and depends on the borrowed amount and the term of the loan, and Rj Tj is the property sale amount. Rj Tj is proportionate to the borrowed amount; the proportionality coefficient is modeled by a geometric Brownian motion and represents the fluctuation price of real estate. The couples (Maturity of the loan, Term of the loan) are modeled by a Poisson point process. The provision Ph, where h is the maximum duration of the loans, is defined as the sum of the random number of individual defaults amounts. We can calculate the mean and the variance of the provision and also give an algorithm to simulate the provision. It is also possible to estimate the parameters of our model and then give a numerical value of the provision quantile. In the second part we will focus on the solvency need due to provisioning risk (topic imposed by the european Solvency 2 reform). The question will be to study the asymptotic behaviour of Ph when h ! +1. We will show that Ph, well renormalized, converges in law to a random variable which is the sum of two random variables whose one is a Gaussian
Bombardelli, Juliana Aparecida. "Avaliação ultrassonográfica da involução dos componentes do cordão umbilical de bezerros holandeses no primeiro mês de vida: influência da concentração da tintura de iodo utilizada para a desinfecção do umbigo." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-20102015-090820/.
Full textDiseases of the umbilical components are very important in the neonatal period. Commonly found in calves, they can lead to serious complications. Diagnosis of umbilical diseases is often not fully enlightened by bimanual abdominal palpation, since this semiotic method is not sensitive enough to determine the extent of involvement of the umbilical intra-abdominal structures in part of the cases. Thus, ultrasonography is a valuable complementary test for establishing an accurate diagnosis on the location and extent of intra-abdominal omphalitis. Because of these limitations and the scarce research on the establishment of the standards of navel ultrasound, the purpose of this study was to evaluate the physiological involution process of umbilical components of healthy calves, considering the use of classic antiseptic, iodine tincture in concentrations 2% and 5%, used in navel treatment during the first days after birth. Evaluation was performed by ultrasonography of umbilical components in different positions and the changes were characterized during the process of involution regarding the appearance of the images, the measures of the diameter and thickness of vascular and urachus components, as well as the peculiarities from the two types of disinfecting. Twenty-three Holstein male calves, reared in dairy property located in the State of São Paulo, were evaluated from birth to 30 days old. Results obtained showed that the vein and umbilical arteries lose their blood vessels characteristics, assuming a ligament aspect due to fibrous tissue proliferation. This process was characteristic and followed a pattern, in which the fibrous tissue was initially present in the inner part of the vessel wall, following with involution, toward the center of the vessel lumen. This process of involution was earlier in the parts of the blood vessels that were farthest from the external navel, with no particular behavior distinct by the use of different antiseptic concentrations. Besides the images, the measurements of the diameter of the umbilical components and the thickness of their walls were also standardized along the physiological involution process during the first 30 days of life the calf, confirming the accuracy of ultrasonography for such assessment and establishing references to improve the diagnosis and the choice of treatment of umbilical diseases
Sharma, Rajhans. "Caractérisation et ciblage de la reconnaissance dynamique de Trp37-G lors de l’interaction de la protéine NCp7 de HIV-1 avec des acides nucléiques." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ014.
Full textNucleocapsid protein (NC) plays crucial roles in HIV-1 life cycle through its nucleic acid (NA) chaperoning property that involves recognition of it’s Trp37 residue with a Guanine residue of the target nucleic acid sequences. Herein, we characterized this dynamic Trp37-G recognition with sequences involved in reverse transcription and genomic RNA packaging. Using the fluorescent thienoguanosine (thG) and 2-thienyl-3-hydroxychromone (3HCnt) nucleoside analogues, we determined the whole set of kinetic rate constants for annealing of (-)PBS with (+)PBS in the absence and presence of NC. We also investigated the role of NA sugar in NC-RNA and NC-DNA complexes, as NC binds with opposite polarity to DNA and RNA sequences. We confirmed that the interaction of the Trp37 residue with guanines was critical for the formation of complexes with both RNA and DNA variants of PBS and SL3. Finally, we performed screening of NC inhibitors and tested the selected hits on a thG-based assay
Andersson, Anna, and Jackman Amanda. "Kan en svalglambå göra skillnad? : En retrospektiv studie av tal hos patienter opererade med svalglambå vid Akademiska sjukhuset i Uppsala 2000-2011." Thesis, Uppsala universitet, Logopedi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-216482.
Full textVelopharyngeal insufficiency (VPI) refers to the failure of separating the oral cavity from the nasal cavity during speech and deglutination. This leads to increased airflow through the nose and is the cause of resonance disturbances such as hypernasality and nasal emission. Previous studies evaluating the success of pharyngeal flap surgery to treat VPI have indicated satisfying result although some studies stress side effects due to postoperative constrictions. The underlying cause of VPI has been shown to influence the postoperative result. With this background we investigated the differences in speech, pre-, and one year post pharyngeal flap surgery and compared the three groups (a) cleft palate, (b) cleft palate in combination with a syndrome or a sequence, and (c) VPI without cleft palate. We also investigated the co-occurance of postoperative speech therapy regarding different speech parameters and the underlying cause of VPI. 66 of the 153 patients who underwent a pharyngeal flap surgery at Akademiska sjukhuset in Uppsala 2000-2011 agreed to participate in the study. 32 patients attended postoperative speech therapy. The data was collected through medical records and a survey and included perceptual analyses of speech pre-, and post surgery performed by speech and language pathologists. According to the results from the perceptual assessment, the pharyngeal flap surgery resulted in improved speech; intelligibility (p<0.001), hypernasality (p=0.005) and weak consonant pressure (p=0.001). Hyponasality did not increase significantly (p=0.55). Patients with cleft palate in combination with a syndrome or a sequence showed greater improvement regarding hypernasality (p=0.037). The only speech disturbance co-occurring with the presence of postoperative speech therapy was compensatory articulation. Patients with cleft palate seemed to receive postoperative speech therapy in a higher extent than patients with cleft palate in combination with a syndrome or a sequence. These results indicate that pharyngeal flap surgery is a successful way of treating VPI disregarding underlying cause. Keywords: Velopharyngeal insufficiency, pharyngeal flap, cleft palate, syndrome, primary VPI, speech deviation, speech therapy
van, Oorschot Michaela [Verfasser], and Samuel [Akademischer Betreuer] Samnick. "Untersuchungen zur Aufnahme und zum Metabolismus von Fluor-18-markierten und von radiojodierten Fettsäuren in primär humanen Prostatakarzinomzelllinien und in einem experimentellen Modell eines humanen Prostatakarzinoms / Michaela van Oorschot. Betreuer: Samuel Samnick." Würzburg : Universität Würzburg, 2013. http://d-nb.info/1102820601/34.
Full textVan, Oorschot Michaela [Verfasser], and Samuel [Akademischer Betreuer] Samnick. "Untersuchungen zur Aufnahme und zum Metabolismus von Fluor-18-markierten und von radiojodierten Fettsäuren in primär humanen Prostatakarzinomzelllinien und in einem experimentellen Modell eines humanen Prostatakarzinoms / Michaela van Oorschot. Betreuer: Samuel Samnick." Würzburg : Universität Würzburg, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-85295.
Full textFont, Valentín Laia. "La gestió dels recursos animals a la Catalunya meridional i de ponent durant la protohistòria (segles VII-I ane). Avaluació econòmica, política i social a partir de les restes de fauna." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/418810.
Full textThe aim of this research is to carry out a zooarchaeological study of various sites dated to the Early Iron Age and Iberian period (7th-1st centuries BC), interpreting the results of the faunal analysis within the respective economic and sociopolitical contexts. The study area includes the southern and western zones of Catalonia. Both are a priori different zones in terms of population from the Bronze Age onwards, and of interaction with the Phoenician colonial world during the Early Iron Age. Both territories also experienced strong transformations during the Iberian Period, in terms of settlement patterns and relations to the nearby resources, at the same time that they were adapting to the arrival of Roman settlers and new ways of production and storage were emerging. In this context, the objective of this work is to analyse the changes and similarities/differences between the zooarchaeological record in a series of contexts. On one hand, materials from five archaeological sites have been analysed: Sant Jaume (Alcanar, Montsià), Ferradura (Alcanar, Montsià), Calvari (el Molar, Priorat), Coll del Moro (Gandesa, Terra Alta) and Missatges (Tàrrega, Urgell), with a total of 5968 bone remains (mammals, birds and fishes) and 773 remains of marine molluscs and crustaceans. On the other hand, the results of this analysis are integrated and compared with available quantitative data from other zooarchaeological studies on sites from the same geographical zone or nearby zones (including data from sites in the País Valencià and Baix Aragó). The work is structured as follows: introduction, objectives, methodology, geographic and historical background of the study area, and state of the art in zooarchaeological quantitative data (taking into account also the quality of these data), in addition to some remarks on consumption, animal husbandry and rituals associated with domestic animals, based on studies by different authors. After these introductory and theoretical chapters, the results of the five sites analysed in this research are presented. This is followed by a discussion of these results, integrating the existing published and available zooarchaeological data from other sites. The conclusions of this study are summarised in the final chapter.
Salou, Thibault. "Combiner Analyse du Cycle de Vie et modèles économiques pour l’évaluation ex-ante d’instruments de politiques publiques – Application au secteur laitier français." Thesis, Rennes, Agrocampus Ouest, 2017. http://www.theses.fr/2017NSARE045/document.
Full textLife Cycle Assessment (LCA) is a multicriteria method to assess environmental impacts of goods and services. In its early stages, LCA, known as Attributional (ALCA), was used to assess environmental impacts in a status-quo situation for benchmarking, environmental communication and product development. Recent methodological developments led to Consequential LCA (CLCA), which aims to quantify direct and indirect impacts of changes, through market mechanisms, allowing for public policy assessment. The aim of this Ph.D. thesis is to develop a methodological framework to assess public policy instruments in the livestock sector by combining LCA and economic modellingThis thesis is organized into three axes: i) identification and characterization of environmental performances of dairy production technologies through ALCA; ii) adaptation of MATSIM-LUCA economic model to the needs of the thesis; iii) environmental impact assessment through CLCA of dairy quota removal and implementation of a grass premium in the European Union. This work provides i) initial development of a methodological framework for assessing public policy instruments in the livestock sector and ii) identification of several improvements needed to make the method operational for stakeholders
Sawadogo, Relwendé. "Essais sur les déterminants et les conséquences macroéconomiques du développement du secteur d’assurance dans les pays en développement." Thesis, Clermont-Ferrand 1, 2016. http://www.theses.fr/2016CLF10493/document.
Full textThis thesis is composed of a set of research in applied economics that enroll in the contemporary field of economics of insurance. The thesis analyses how developing countries could develop more the insurance sector and benefit from these effects on local economy. The first part explored the determinants of insurance development from a macroeconomic perspective. First, the results show that increase of income per capita leads to an increase in life insurance premiums and that life insurance is a luxury commodity in Sub-Saharan Africa (chapter 2). We also find evidence that the marginal impact of income varies according to the quality of legal and political environment. Second, analysis of effect of the FDI inflows shows that these are a key factor in increase of non-life insurance premiums in countries of Sub-Saharan Africa (SSA) and in other developing countries (chapter 3). In chapter 4, the results highlighted that the activities of life insurance and banking are substitutable in SSA and, however, there is presence of unidirectional causality running from real private credit density to life insurance and insurance density. The second part of the thesis has analysed effect of development of insurance sector on economy in developing countries. First, it appears that the development of life insurance has a positive effect on economic growth on the one hand and on the other hand marginal effect of life insurance is influenced by the structural characteristics of countries (chapter 5). In chapter 6, the results showed that the insurance premiums significantly increase stock market value traded, before as well and after the 2007's economic crisis. Finally, the thesis showed that there is a long term relationship between the development of non-life insurance and trade openness and that non-life insurance premiums improve openness to international trade as well in developing countries than specifically in low and middle income countries (chapter 7)
Merli, Vanessa. "L'esperimento di Grimaldi e la storia della diffrazione." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16771/.
Full textEbersohn, Elizabeth Mary Anne. "Riglyne vir 'n sosiaal-perseptuele onderrigprogram vir senior primere leergestremde leerlinge." Thesis, 2014. http://hdl.handle.net/10210/11654.
Full textAlthough the learning disabled pupil has an average to above average intellectual ability, he does not perform accordingly. Not only does he reveal academic deficiencies, but social and emotional deficiencies are also part and parcel of his problem. Furthermore he experiences problems in meeting social demands that are made in his every day life. These deficiencies in his social abilities in turn imply an insufficient recognition of social demands. Research has shown that a learning disabled pupil's social perceptions are weaker than those of a normal pupil. Although the learning disabled pupil's academic short-coming are at first recognised by the teacher, his social problems are normally neither identified nor understood. The learning disabled child should .be assisted to acquire social skills. In this process the teacher could playa vital role. From previous studies, insight regarding the learning disabled pupil, has been gained. The etiology and manifestations of learning disabilities have been discussed and the characteristics of deficient social skills have also been scrutinised. The purpose of this research is to determine certain disorders regarding the social perceptions of a learning disabled child. Criteria as well as guidelines that a social-perceptual education programme should meet, are also suggested. The study was conducted with 60 learning disabled pupils forming the experimental group and 60 non-learning disabled pupils forming the control group. The "Coding of Emotional Responses Test" was used in this study. In this study it became apparent that the learning disabled pupils made significantly more errors than the control group (nonlearning disabled pupils). Therefore the learning disabled pupil experiences difficulty in interpreting non-verbal behaviour patterns such as facial expressions, body language and gestures correctly, as a result of his deficient social perceptions. Criteria programme research. and guidelines for a social-perceptual education have been determined as a result of this...
Badenhorst, Charlotte Henrietta. "Psigiese lewensaktualisering van die afknouer in die primere skool." Diss., 2013. http://hdl.handle.net/10500/10590.
Full textDie doelstelling van hierdie kwalitatiewe navorsing was om die leerder in die primêre skool, wat ander afknou, se psigiese lewensaktualisering te verken en te beskryf. Om hierdie doelstelling te bereik, is bepaalde doelwitte gestel. Deur middel van ’n literatuurstudie is ondersoek ingestel na die ontwikkeling van die leerder in die middelkinderjare. Voorts is die konsep van afknouery ondersoek, om sodoende ‘n psigiese beeld te kan skep van die leerder wat ander afknou. Projeksiemedia is in drie gevallestudies gebruik om empiriese inligting rakende die doel van die navorsing te bekom. Temas is uit die projeksiemedia geïdentifiseer en teen die bestaande literatuur geverifieer. Tydens die bespreking van die inligting wat uit die projeksiemedia verkry is, is gevolgtrekkings en aanbevelings gemaak. Daar is gepoog om die bevindinge nie te veralgemeen nie, omdat dit ‘n kwalitatiewe studie was.
The aim of this qualitative study was to explore and describe the psychological life actualization of the learner in primary school who bullies others. To achieve this goal, specific objectives were set. The development of the learner in middle childhood was examined by means of a literature investigation. Furthermore, the concept of bullying was investigated, thus creating a psychological image of the learner who bullies others. Projection media were used in three case studies to obtain empirical information regarding the objective of the research. Themes from the projection media were identified and verified against the existing literature. During the discussion of the information acquired from the projection media, conclusions and recommendations were made. An attempt was made not to generalize the findings, because this was a qualitative study.
Psychology of Education
M. Ed. (Voorligting)
Venter, Martin. "Die funksies van die departementshoof : junior primêr as indiensopleier." Thesis, 2014. http://hdl.handle.net/10210/10611.
Full textRaubenheimer, Lorinda Riana. "Implementering van spel in die Gr R klas in die preprimere en primere skool." Diss., 2012. http://hdl.handle.net/10500/6034.
Full textSpel kan gesien word as ’n baie belangrike komponent van die leerprogram vir voorskoolse kinders. Die vraag ontstaan of Gr R onderwyseresse genoegsame spel in die dagprogram implementeer? Die navorsingsvraag is as volg beantwoord. Alhoewel dit in die studie na vore gekom het, dat die onderwyseresse wat preprimêr en BEd gekwalifiseer is oor die meeste speelkennis beskik, het die meeste Gr R onderwyseresse aangedui dat hul wel ’n behoefte het om meer kennis rakende kinderspel en die implementering daarvan in die dagprogram te bekom. Die laaste vraag voortvloeiend uit die navorsing of daar genoegsame spel in die Gr R klasse plaasvind was die gevolgtrekking “nee” by primêre skole en “ja” by preprimêre skole. Daar is tot die gevolgtrekking gekom dat Gr R onderwys by primêre skole se onderrigmetodes baie meer formeel is as Gr R by preprimêre skole. Die navorsings-vraag is dus in geheel beantwoord en die studie is suksesvol voltooi.
Psychology of Education
M. Ed. (Sielkundige Opvoedkunde)