Journal articles: 'Viola odorata'

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Weeks, L. A. "Viola Odorata." Colorado Review 46, no. 1 (2019): 156. http://dx.doi.org/10.1353/col.2019.0044.

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Bahemann, Alois. "Viola odorata - zwei Fšlle." Zeitschrift für Klassische Homöopathie 46, no. 01 (March 30, 2007): 13–17. http://dx.doi.org/10.1055/s-2006-938810.

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Buabeid, Manal Ali, El-Shaimaa A. Arafa, Waseem Hassan, and Ghulam Murtaza. "In Silico Prediction of the Mode of Action of Viola odorata in Diabetes." BioMed Research International 2020 (October 30, 2020): 1–13. http://dx.doi.org/10.1155/2020/2768403.

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Background. The metabolic syndrome increases the risk of different diseases such as type 2 diabetes. The prevalence of metabolic syndrome has rapidly grown and affected more than 230 million people worldwide. Viola odorata is a traditionally used plant for the treatment of diabetes; however, its mechanism to manage diabetes is still unknown. Purpose. This study was designed to systematically assess the mechanism of action of Viola odorata in diabetes. Methods. An extensive literature search was made to establish an ingredient-target database of Viola odorata. Of these, targets related to diabetes were identified and used to develop a protein-protein interaction network (PPIN) by utilizing the STITCH database. The obtained PPIN was assessed through Gene Ontology (GO) enrichment analysis based on ClueGO plugin. Results. According to the acquired data, there were about 143 chemical constituents present in Viola odorata having 119 protein targets. Of these, 31 targets were established to give the pharmacological effect against diabetes. The UniProt database was used for screening of 31 targets, out of which Homo sapiens contained 22 targets. Ultimately, 207 GO terms, grouped into 41 clusters, were found by gene analysis, and most of them were found to be linked with diabetes. According to findings, several proteins including TP53, BCL2, CDKN1A, 1L6, CCND1, CDKN2A, and RB1 have a significant role in the treatment of diabetes by Viola odorata. Conclusion. The possible activity of Viola odorata in the management of diabetes may be mediated by several molecular mechanisms, including the glutamine metabolic process, IRE1-mediated unfolded protein response, and pentose metabolic process.

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Holzapfel, Klaus. "Viola odorata - Pathogenese eines Irrtums." Zeitschrift für Klassische Homöopathie 49, no. 1 (January 2005): 40–42. http://dx.doi.org/10.1055/s-2005-862517.

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Reecha Madaan, Rajni Bala, Anuja Verma, and Rajdeep Sarma. "Determination of Sunscreen activity of Viola odorata (Banafsha) ethanolic extract and its formulated Gel by UV Spectroscopy." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (January 7, 2020): 154–59. http://dx.doi.org/10.26452/ijrps.v11i1.1800.

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In the present study, ethanolic extract of Banafsha i.e., Viola odorata (Violaceae) and its gel formulations was evaluated for its sun protection activity by ultraviolet spectroscopy method. The phytoconstituents like flavonoids, phenolics present in Viola odorata may be responsible for scavenging action on UV-induced reactive oxygen species. Extraction of aerial parts of the plant was done in the Soxhlet apparatus using ethanol as solvent. 1ml, 2ml, and 4ml of ethanol extract (200µg/ml) of the plant were used to formulate three gels (F1-F3) using Carabopol 940, 0.5% Methyl paraben, 0.2% Propyl paraben, Propylene glycol 400 and Triethanolamine. Mansur et al. UV spectrophotometric method was used to investigate the in vitro SPF of the Viola odorata ethanolic extracts (100&200µg/ml) and its formulated gels (F1-F3). Physical parameters like color, appearance, spreadability, pH, homogeneity, viscosity were determined to evaluate formulated gels. Based on the calculated SPF value, F3 formulation was chosen for the stability study. Ethanolic extract of Viola odorata (100 µg/ml and 200µg/ml) have SPF value 4.05±0.07 and 11.66±0.04, respectively. Gel formulations (F1-F3) containing 1, 2,4ml of 200µg/ml of ethanol extract have SPF values about 2.89±0.11, 4.20±0.08, and 5.63±0.07, respectively. The SPF values determined to confirm the capacity of gels to absorb UV radiation. No significant alterations in physicochemical parameters and SPF values were observed during the stability evaluation of F3 gel. Results proves that Viola odorata is a safe alternative which can be used over harmful chemical sunscreens used now a days in the industry and in the future plant can be explored for active component for better protection against sun rays.

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Manosi Das, Subhendu Mondal, Shreya Ghosal, Avijit Banerji, Amit Kumar Dixit, and P V V Prasad. "Phyto-pharmacognostical evaluation and HPTLC finger printing profile of Gulbanafsha (Viola odorata L.) flower." GSC Biological and Pharmaceutical Sciences 14, no. 1 (January 30, 2021): 183–92. http://dx.doi.org/10.30574/gscbps.2021.14.1.0410.

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Viola odorata Linn. (Family Violaceae) is popularly known as Sweet Violet or English Violet and Gulbanafsha in Hindi. V. odorata is used as remedy for coughs, sore throat, hoarseness and tonsillitis. It is valued as an expectorant, antioxidant, diaphoretic, antibacterial, antipyretic and diuretic. Pharmacological studies have revealed the role of V. odorata in Unani drugs for treatment of common cold, asthma and cough associated diseases. The present study focuses on the phyto-pharmacognostical evaluation and HPTLC finger printing profile of Gulbanafsha (Viola odorata L.) flower - white variety. Physicochemical parameters were determined and phytochemical screening done by standard procedures. HPTLC finger-printing profile of the methanolic extracts of dried flowers, were performed on precoated TLC silica gel 60F254 plateswith salicylic acid as marker. Phytochemical screening revealed presence of flavonoids, glycosides, phenolic compounds/tannins.

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Tafazoli, Vahid, Mahdi Shahriari, Mojtaba Heydari, Hosein Ali Nikbakht, Mohammad M. Zarshenaas, and Majid Nimrouzi. "The Effect of Viola Odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial." Current Drug Discovery Technologies 17, no. 5 (December 23, 2020): 696–703. http://dx.doi.org/10.2174/1570163816666190620142256.

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Introduction: Finding non-systemic antipyretic option in cancer patients who simultaneously receive several other drugs seems be logical. This study was designed to evaluate complementary therapy with Viola odorata L. oil for fever control in febrile neutropenic children. Methods and Materials: In a randomized placebo controlled clinical trial, 41 febrile children were divided into two groups. Children in the active drug group received viola oil (20 drops) to be rubbed on the peripheral margin of the patient umbilicus. Primary outcome measure of the study was the mean axillary temperature in the 30, 60, and 240 minutes after the intervention. Results: The mean temperature reduced significantly in the viola group after 30 minutes of administration (p =0.005), while there was no significant change in the placebo group (p =1.00). The number of patients who received paracetamol as the rescue treatment was significantly lower in the viola group than that in the placebo group (5 vs. 17, p =0.001). Conclusion: The results of our study showed the safety and efficacy of complementary therapy with Viola odorata L. oil for fever control in febrile neutropenic children during hospital course.

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Jasim, Shaimaa Fakhri, Noor Nihad Baqer, and Esam Abd Alraheem. "DETECTION OF PHYTOCHEMICAL CONSTITUENT IN FLOWERS OF VIOLA ODORATA BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 5 (May 1, 2018): 262. http://dx.doi.org/10.22159/ajpcr.2018.v11i5.24288.

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Objective: Viola odorata has a characteristic as antifungal, antibacterial, anticancer, antioxidant, antiasthmatic, anti-inflammatory, anti-HIV, and antipyretic agents. The aim of this study was detected about bioactive compounds in the methanolic extract of V. odorata. Methods: The methanolic extract was analyzed through gas chromatography-mass spectrometry (GC-MS) for the identification of different compounds.Results: The current study investigated about phytochemicals in flowers of V. odorata. GC-MS analysis of the methanol extract of flowers showed 84 compounds. The highest concentration was for components which include ethanol, 2-(9,12-octadecadienyl oxy) -, (Z,Z)-; pentadecanoic acid; 1-pentacosanol; 1-pentacosanol; 2-furan carboxaldehyde, 5-(hydroxymethyl)-; 1,2 benzenedicarboxylic acid, diisooctyl ester; and docosane, 11-butyl- and gamma-sitosterol. The peak area and retention time for each components, respectively, were (15.709, 25.51%), (14.015, 19.51%), (29.914, 4.69%), (27.292, 3.95%), (5.707, 4.05%), (20.357, 3.91%), (18.289, 2.48%), and (30.431, 2.37%). While the others components ranged the peak area from 2.03% to 0.05%.Conclusions: These results indicate that the flowers of V. odorata contain the numerous components which have medical importance and this study was one of the first studies to detect phytochemicals in V. odorata.

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Trkulja, N., A. Milosavljević, S. Živković, T. Popović, M. Mitrović, J. Jović, and I. Toševski. "First Report of Cercospora violae Infecting the Garden Violet Viola odorata in Serbia." Plant Disease 99, no. 7 (July 2015): 1035. http://dx.doi.org/10.1094/pdis-10-14-1096-pdn.

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Singh, Ajeet, Shweta Dhariwal, and Navneet. "Traditional uses, Antimicrobial potential, Pharmacological properties and Phytochemistry of Viola odorata: A Mini Review." Journal of Phytopharmacology 7, no. 1 (January 22, 2018): 103–5. http://dx.doi.org/10.31254/phyto.2018.7120.

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Viola odorata Linn. is belongs to the family violaceae. It is popularly known as Sweet Violet, English Violet, Common Violet, or Garden Violet and Gulbanafsa in Hindi. V. odorata is commonly used as remedy for coughs, sore throat, hoarseness and tonsillitis. It is valued as an expectorant, antioxidant, diaphoretic, antibacterial, antipyretic, diuretic and as a laxative. The pharmacological studies revealed the role of V. odorata in some Unani drugs for treatment of common cold, asthma, antimicrobial, and cough associated diseases. It is rich in many phytoconstituents such as, saponins, salicylates, alkaloids, flavonoids, saponins, tannins, phenolics, coumarins, phenolic glycosides, gaultherin, violutoside, saponins, flavonoids, and odoratine. It is an ethnobotanical herb of India. It holds a special position as a potent adaptive and aphrodisiac in Ayurvedic System of Medicine

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Mulla, İmamuddin, Mariyam Roqaiya, and Mohd Imran Khan. "Efficacy of Viola odorata flower decoction in chronic rhinosinusitis." Medical Journal of Islamic World Academy of Sciences 27, no. 3 (2019): 77–84. http://dx.doi.org/10.5505/ias.2019.08379.

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Parsley, Nicole C., Christine L. Kirkpatrick, Christopher M. Crittenden, Javad Ghassemi Rad, David W. Hoskin, Jennifer S. Brodbelt, and Leslie M. Hicks. "PepSAVI-MS reveals anticancer and antifungal cycloviolacins in Viola odorata." Phytochemistry 152 (August 2018): 61–70. http://dx.doi.org/10.1016/j.phytochem.2018.04.014.

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Narayani, M., M. K. N. Sai Varsha, Uma Rani Potunuru, W. Sofi Beaula, Suresh Kumar Rayala, Madhulika Dixit, Anju Chadha, and Smita Srivastava. "Production of bioactive cyclotides in somatic embryos of Viola odorata." Phytochemistry 156 (December 2018): 135–41. http://dx.doi.org/10.1016/j.phytochem.2018.09.008.

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Nikoleta Kallajxhiu, Gëzim Kapidani, Silvana Turku, and Anxhela Dauti. "Comparative palynomorphological study of two species in the valley of Zagoria, Gjirokastra, Albania." GSC Biological and Pharmaceutical Sciences 15, no. 3 (June 30, 2021): 199–205. http://dx.doi.org/10.30574/gscbps.2021.15.3.0164.

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In this study there are demonstrated for the first time in albanian literature the palynomorphologic characteristics of two types of plants (Centaurea epirota and Viola epirota), collected in Zagoria valley, Gjirokastra region, in Albania. To carry out the study, light microscopy was used and it was concluded that the pollen grains of Centaurea epirota were 3 colporate, isopolar, with radial symmetry. In the polar view, the pollen grains have a circular triangular shape while in the equatorial view they have a compressed oval shape. Exine appeared scabrate. Viola epirota consisted of 3-4 colporate, sometimes even 5 colporate pollen grains. In the polar view, the pollen grains had a circular shape of 3 or 4 angles, sometimes even 5 angles while in the equatorial view they had an elliptical shape. Exine appeared granulate. To see the impact of ecological factor and the method of laboratory processing of pollen grains, the size of the new species studied was compared with the size of the pollen grains of Centaurea cyanus and Viola alba, Viola odorata and Viola arvensis, taken from the native literature.

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Janbaz, Khalid Hussain, Waseem Ullah Khan, Fatima Saqib, and Mamoona Khalid. "Pharmacological basis for the medicinal use of Viola odorata in diarrhea, bronchial asthma and hypertension." Bangladesh Journal of Pharmacology 10, no. 4 (October 19, 2015): 836. http://dx.doi.org/10.3329/bjp.v10i4.23889.

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Viola odorata is traditionally used in the management of gastrointestinal, respiratory and vascular disorders. The present study was undertaken to validate its folkloric uses. The application of V. odorata to spontaneous contractions in isolated rabbit jejunum preparation exerted relaxant effect through decrease in magnitude and frequency of contractions. Moreover, it also caused relaxation of K+ (80 mM)-induced contractions and shifted the Ca2+ concentration response curves toward right in isolated jejunum similar to verapamil (standard Ca2+ channel blocker), confirming Ca2+ channel blocking activity. V. odorata also caused relaxation of carbachol (1 µM)- and K+ (80 mM)-induced contractions in isolated rabbit tracheal preparations comparable to verapamil, reflecting that observed relaxant effect may be the outcome of anti-muscarinic and/or Ca2+ channel blocking activities. It also exerted relaxant effect on phenylephrine (1 µM)- and K+ (80 mM)-induced contractions in isolated rabbit aortic preparations thus providing rationale for its folkloric uses to treat diarrhea, asthma and hypertension.

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Kannappan, N., Anupama Diwan, Pooja Saini, Sandeep Singh, Vishal Antil, and Parveen Kumar. "Evaluation of the analgesic activity of Viola odorata aerial parts in rats." Journal of Natural Pharmaceuticals 2, no. 1 (2011): 24. http://dx.doi.org/10.4103/2229-5119.78493.

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Svangård, Erika, Ulf Göransson, Derek Smith, Chandra Verma, Anders Backlund, Lars Bohlin, and Per Claeson. "Primary and 3-D modelled structures of two cyclotides from Viola odorata." Phytochemistry 64, no. 1 (September 2003): 135–42. http://dx.doi.org/10.1016/s0031-9422(03)00218-8.

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Shafaghat, Zahra, Fatemeh Zarinkamar, and Mehrdad Nazari. "Ultraviolet-B radiation induces physiological, biochemical, and structural changes in Viola odorata." Vegetos 33, no. 3 (July 16, 2020): 545–54. http://dx.doi.org/10.1007/s42535-020-00139-0.

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Siddiqi, Hasan S., Malik H. Mehmood, Najeeb U. Rehman, and Anwar H. Gilani. "Studies on the antihypertensive and antidyslipidemic activities of Viola odorata leaves extract." Lipids in Health and Disease 11, no. 1 (2012): 6. http://dx.doi.org/10.1186/1476-511x-11-6.

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Petrova, Natal'ya Valeriyevna, and Nina Anatol'yevna Medvedeva. "COMPONENT COMPOSITION AND BIOLOGICAL ACTIVITY OF GENUS VIOLA (VIOLACEAE) OF RUSSIAN FLO-RA." chemistry of plant raw material, no. 2 (June 10, 2020): 19–45. http://dx.doi.org/10.14258/jcprm.2020026305.

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The subject of the review is the component composition and biological activity of species of genus Viola L. (Violaceae) from the flora of the Russian Federation according publications appeared over the past few decades. Chemical constituents and biological activities have been reported for 24 species of the 100 Viola species occurring in Russian. Components of various structures: flavonoids, cyclotides, anthocyanidins, phenylpropanoic acids, coumarins, alkaloids, fatty acids and its derivatives and ect. were found in the roots, aerial parts, flowers and leaves. Composition of 137 flavonoids, alkaloids, coumarins etc. was expanded with references to their chemical formulas and literature sources. Data of the essential oils isolated from the leaves of V. tricolor L., V. arvensis Murray, V. yedoensis Makino и V. odorata L. is systematized. It was demonstrated that extracts, their fractions, and some components showed different types of biological activity, including anti-inflammatory, cytotoxic and antiviral ones. The revealed range of biological activity partially confirmed expediency of using species of genus Viola in folk and standard practice medicine.

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Asthana, Monika. "Dose Response of Viola odorata on Meiotic and Mitotic Chromosomes of Vicia faba." British Journal of Pharmaceutical Research 4, no. 4 (January 10, 2014): 520–30. http://dx.doi.org/10.9734/bjpr/2014/5998.

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Jamshed, Humaira, Hasan Salman Siddiqi, Anwar‐ul‐Hassan Gilani, Jamshed Arslan, Muhammad Qasim, and Bilquees Gul. "Studies on antioxidant, hepatoprotective, and vasculoprotective potential of Viola odorata and Wrightia tinctoria." Phytotherapy Research 33, no. 9 (June 17, 2019): 2310–18. http://dx.doi.org/10.1002/ptr.6411.

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MARCUSSEN, THOMAS. "Allozymic variation in the widespread and cultivated Viola odorata (Violaceae) in western Eurasia." Botanical Journal of the Linnean Society 151, no. 4 (August 2006): 563–71. http://dx.doi.org/10.1111/j.1095-8339.2006.00543.x.

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Darvishani, Seyedeh Nastaran Hosseini, Esmaeil Chamani, Vali Ollah Ghasemi Omran, Behrouz Esmaeilpour, and Yasser Yaghoubian. "In-vitro PHYSIOCHEMICAL RESPONSES OF Viola odorata PLANT TO COMBINED SALT AND DROUGHT STRESS." Acta Scientiarum Polonorum Hortorum Cultus 19, no. 4 (August 28, 2020): 53–62. http://dx.doi.org/10.24326/asphc.2020.4.5.

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Nowadays sweet violet (Viola odorata) is an ornamental-medical plant that considered as endangered and threatened species. On the other hand, biotic and abiotic stresses impose a major threat to agriculture. Here, we investigated the effects of salinity and drought stresses, based on polyethylene glycol (PEG; 1, 1.5, 2, 2.5, 3 and 4%) and NaCl (0, 50, 100 and 150 mM), on growth characteristics, physiological parameters and antioxidant defense system of sweet violet under in-vitro conditions. The influences of NaCl and PEG gradients in the culture media on plant height, green leaf percentage, root dry weight (DW), and electrolyte leakage (EL) was described by a linear or quadratic model. All measured parameters (except EL) decreased when NaCl or PEG concentration increased. In contrast, EL increased other traits. Moreover, with increasing in salinity and drought severity, shoot DW decreased, while antioxidant enzymes activity such as catalase (CAT), peroxidase (POX) and superoxide dismutase (SOD) and proline content increased. However, total soluble carbohydrates (TSC), at all drought levels, increased with increasing NaCl concentration up to 50 or 100 mM, and then decreased. Most variations in the shoot DW, CAT activity, proline and TSC contents due to salt stress occurred at low concentration of PEG. Overall, our findings highlight that the effect of combined drought and salt stress was more severe. However, the sensitivity of the plant to drought or salinity stress was higher in the absence of other stress.

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Van Caneghem, A., A. Poupet, D. Beck, and E. Berling. "Obtention de clones de violettes (Viola odorata) indemnes de virus par culture d'apex méristématique." Agronomie 17, no. 1 (1997): 53–58. http://dx.doi.org/10.1051/agro:19970107.

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Erdogan Orhan, Ilkay, Fatma Sezer Senol, Sinem Aslan Erdem, I. Irem Tatli, Murat Kartal, and Sevket Alp. "Tyrosinase and Cholinesterase Inhibitory Potential and Flavonoid Characterization of Viola odorata L. (Sweet Violet)." Phytotherapy Research 29, no. 9 (June 9, 2015): 1304–10. http://dx.doi.org/10.1002/ptr.5378.

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Qasemzadeh, Mohammad Javad, Hosein Sharifi, Mohammad Hamedanian, Mohammad Gharehbeglou, Mojtaba Heydari, Mehdi Sardari, Meisam Akhlaghdoust, and Mohammad Bagher Minae. "The Effect of Viola odorata Flower Syrup on the Cough of Children With Asthma." Journal of Evidence-Based Complementary & Alternative Medicine 20, no. 4 (May 6, 2015): 287–91. http://dx.doi.org/10.1177/2156587215584862.

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This study aimed to investigate the effect of violet syrup on cough alleviation in children with intermittent asthma. In a parallel, double-blind, randomized controlled trial, 182 children aged 2 to 12 years with intermittent asthma were randomly assigned 1:1 to receive violet syrup or placebo along with the common standard treatments in both groups (short-acting β-agonist). Both groups were evaluated in terms of the duration until cough suppression was achieved. No significant difference was observed in basic characteristics. The duration lasting to yield more than 50% cough reduction and 100% cough suppression was significantly less in the violet syrup group compared to placebo ( P = .001, P < .001, respectively). There was no significant difference in therapeutic effects between boys and girls. There was a significant inverse correlation between the age of children and rate of cough alleviation and suppression by violet syrup. This study showed that the adjuvant use of violet syrup with short-acting β-agonist can enhance the cough suppression in children with intermittent asthma.

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Gautam, Shiv Shanker, Navneet, and Sanjay Kumar. "The Antibacterial and Phytochemical Aspects of Viola odorata Linn. Extracts Against Respiratory Tract Pathogens." Proceedings of the National Academy of Sciences, India Section B: Biological Sciences 82, no. 4 (August 2, 2012): 567–72. http://dx.doi.org/10.1007/s40011-012-0064-7.

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Wijowska, Magdalena, E. Kuta, and Leslaw Przywara. "Autonomous endosperm induction by in vitro culture of unfertilized ovules of Viola odorata L." Sexual Plant Reproduction 12, no. 3 (September 21, 1999): 164–70. http://dx.doi.org/10.1007/s004970050188.

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Katoch, Meenu, Arshia Singh, Gurpreet Singh, Priya Wazir, and Rajinder Kumar. "Phylogeny, antimicrobial, antioxidant and enzyme-producing potential of fungal endophytes found in Viola odorata." Annals of Microbiology 67, no. 8 (July 18, 2017): 529–40. http://dx.doi.org/10.1007/s13213-017-1283-1.

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Gorczyński, Tadeusz. "Badania histo-cytologiczne nad kwiatami kleistogamicznemi u Lamium amplexicaule, Oxalis acetosella i VioIa odorata [Recherches histo-cytologiques sur les fleurs cléistogames chez Lamium amplexicaule, Oxalis acetosella et Viola odorata]." Acta Societatis Botanicorum Poloniae 6, no. 3 (2017): 248–95. http://dx.doi.org/10.5586/asbp.1929.015.

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Samaha, Ali A., Mirna Fawaz, Ali Salami, Safaa Baydoun, and Ali H. Eid. "Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial." Biomolecules 9, no. 7 (July 20, 2019): 292. http://dx.doi.org/10.3390/biom9070292.

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Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study is to document this traditional knowledge and clinically test the antihypertensive capacity of three of the most commonly used wild plant species Mentha longifolia, Viola odorata and Urtica dioica. Ethno-pharmacological data was collected by personal interviews with herbalists and traditional healers using a semi structured survey questionnaire and assessing relative frequency of citation (RFC). The clinical study was conducted by a randomized, blind, placebo-controlled trial in 29 subjects with mild hypertension distributed in four groups, three plant extract treatments and one placebo. Systolic (SBP) and diastolic blood pressures (DBP) as well as mean arterial blood pressures (MAP) were monitored at weeks 4, 8, 12 and 16 during the treatment with 300 mL/day of plant extract. Results showed that M. longifolia, U. dioica and V. odorata exhibited the highest values of RCF (0.95) followed by Allium ampeloprasum (0.94), Apium graveolens (0.92) and Crataegus azarolus (0.90). The clinical trial revealed dose- and duration-dependent significant reductions in SBP, DBP and MAP of subjects treated with M. longifolia, U. dioica or V. odorata. Our findings indicate that extracts of these plants present an effective, safe and promising potential as a phyto-therapuetical approach for the treatment of mild hypertension. More research on the phytochemistry, pharmacological effects and the underlying mechanisms is necessary.

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Mokhtari, Arash, Mohsen Zarei, Behnaz Samsamzadeh, and Kosar Moradi. "Interactive effects of plant growth regulators and explants on direct shoot regeneration of Viola odorata." BioTechnologia 1 (2016): 33–39. http://dx.doi.org/10.5114/bta.2016.58542.

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Pranting, M., C. Loov, R. Burman, U. Goransson, and D. I. Andersson. "The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria." Journal of Antimicrobial Chemotherapy 65, no. 9 (June 17, 2010): 1964–71. http://dx.doi.org/10.1093/jac/dkq220.

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Habibi, Emran, Milad Arab-Nozari, Pedram Elahi, Maryam Ghasemi, and Fatemeh Shaki. "Modulatory effects of Viola odorata flower and leaf extracts upon oxidative stress-related damage in an experimental model of ethanol-induced hepatotoxicity." Applied Physiology, Nutrition, and Metabolism 44, no. 5 (May 2019): 521–27. http://dx.doi.org/10.1139/apnm-2018-0559.

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Ethanol is the most widely abused drug in the world and its long-term use induces oxidative stress in the liver tissue. The aim of this study was to evaluate protective effect of Viola odorata against ethanol-induced hepatotoxicity in Wistar rat. Animals were divided into 9 groups as follows: control (normal saline), ethanol (10 mg/kg, intraperitoneally), ethanol with 3 doses (125, 250, and 500 mg/kg) of ethyl acetate flower and leaf extracts, and positive control (vitamin E 80 mg/kg). Animals were gavaged 30 min before ethanol injection for 28 days. Then, animals were killed and the livers were separated. Oxidative stress parameters, including reactive oxygen species, lipid peroxidation, and protein carbonyl as well as glutathione content, were evaluated. Also, histopathological examination was performed and assessment of blood alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and total antioxidant capacity were evaluated. Ethanol significantly increased oxidative stress markers in liver. Interestingly, administration of both extracts significantly decreased oxidative stress markers in liver tissue and biochemical parameters in the plasma. In addition, abnormal pathological features were improved after treatment with flower and leaf extracts. These results suggested that V. odorata can be considered a candidate for improving conditions due to ethanol-induced tissue oxidative damage because of its antioxidant activity.

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Gorczyński, Tadeusz. "Z badań nad kleistogomją III. Dymorfizm kwiatowy u fijołka wonnego pełnokwiatowego (Viola odorata fl. pleno hort)." Acta Societatis Botanicorum Poloniae 9, no. 1-2 (2017): 115–30. http://dx.doi.org/10.5586/asbp.1932.006.

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SD, Jagadeesh Singh, Meenakshi P. Singh, and Rajesh R. "The efficacy of polyherbal formulation of Moringa oleifera, Viola odorata, Allium sativum against microbes- synergistic effect." Indian Journal of Pharmaceutical and Biological Research 3, no. 04 (December 31, 2015): 06–10. http://dx.doi.org/10.30750/ijpbr.3.4.2.

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The purpose of our present study is to test antimicrobial and antifungal activity of polyherbal formulations. The testing of the antimicrobial activity on polyhernal formulation was done against gram positive (Staphylococcus aureus, Bacillus subtilis) and gram negative (Salmonella typhi, Escherichia coli,) bacteria. The testing of antifungal activity was done against Aspergillus niger and Candida albicans with different combinations of polyherbal formulation. The microorganism to be tested was grown in relevant nutritional media. The solvent used for the extraction of Moringa oleifera, Viola odorata, Allium sativum was methanol. These methanolic extracts of chosen plants were further used in specific proportions for the preparation of polyherbal formulation (PF-1, PF-2, and PF-3). The resultant compositions were further used to check the efficacy against selected experimental microorganisms. PF-3 showed the significant high zone of inhibition against all the experimental microorganisms as compared to the other two combinations PF-1 and PF-2. Thus, the result has revealed that the antimicrobial activity is due to the synergistic effect of secondary metabolites present in these selected plants.

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Gerlach, Samantha L., Ramesh Rathinakumar, Geetika Chakravarty, Ulf Göransson, William C. Wimley, Steven P. Darwin, and Debasis Mondal. "Anticancer and chemosensitizing abilities of cycloviolacin O2 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa." Biopolymers 94, no. 5 (May 26, 2010): 617–25. http://dx.doi.org/10.1002/bip.21435.

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Aslam, Lubna, Ramanjeet Kaur, Nisha Kapoor, and Ritu Mahajan. "Phytochemical composition and antioxidant activities of leaf extracts of Viola odorata from Kishtwar, Jammu and Kashmir." Journal of Herbs, Spices & Medicinal Plants 26, no. 1 (October 24, 2019): 77–88. http://dx.doi.org/10.1080/10496475.2019.1677839.

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Yousefnia, S., D. Naseri, F. Seyed Forootan, M. Tabatabaeian, F. Moattar, T. Ghafghazi, M. H. Nasr Esfahani, and K. Ghaedi. "Suppressive role of Viola odorata extract on malignant characters of mammosphere-derived breast cancer stem cells." Clinical and Translational Oncology 22, no. 9 (February 13, 2020): 1619–34. http://dx.doi.org/10.1007/s12094-020-02307-9.

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Ireland, David C., Michelle L. Colgrave, Philip Nguyencong, Norelle L. Daly, and David J. Craik. "Discovery and Characterization of a Linear Cyclotide from Viola odorata: Implications for the Processing of Circular Proteins." Journal of Molecular Biology 357, no. 5 (April 2006): 1522–35. http://dx.doi.org/10.1016/j.jmb.2006.01.051.

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Yousefi, Mojtaba, Elham Khanniri, Mahdi Shadnoush, Nasim Khorshidian, and Amir M. Mortazavian. "Development, characterization and in vitro antioxidant activity of chitosan-coated alginate microcapsules entrapping Viola odorata Linn. extract." International Journal of Biological Macromolecules 163 (November 2020): 44–54. http://dx.doi.org/10.1016/j.ijbiomac.2020.06.250.

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Savinykh, Natalya, and Marya Shakleina. "Biomorph Limosella aquatica L. and its contribution in stolon-rosette water grasses formation." BIO Web of Conferences 24 (2020): 00073. http://dx.doi.org/10.1051/bioconf/20202400073.

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The paper presents comparative-morphological analysis of biomorphs Limosella aquatica L., stolon-rosette perennial mesophyte grasses (Viola odorata L.), and yearling vegetative hydrophytes (Stratiotes aloides L. and Hydrocharis morsus-ranae L.). It is shown that L. aquatica is a monopodial growing monocarpic with side stolon-rosette shoots and their systems with up to four branching orders. The primary shoot, as well as rosette parts of stolon-rosette shoots, is made of metamers with foliage leafs, axil complexes with differently sets of constituents: two collateral buds and/or their derivatives: flower buds/flowers/fruit, side stolon-rosette shoots or their systems. At the initial stage the shoot-forming mode of L. aquatica is similar to that of V. odorata: a monopodial rosette one with green assimilating leaves, flowers, and stolon-rosette shoots. But iterative branching of stolon-rosette shoots changes the shoot-forming mode of L. aquatica to a sympodial semirosette as in S. aloides, and especially in H. morsus-ranae. Biomorph L. aquatica combines the features of stolon-rosette perennial mesophyte grasses and stolon-rosette yearling vegetative hydrophytes: stolon-rosette shoot formation from axil buds, iterative branching, collateral buds, reduction inflorescence to one flower (S. aloides). Thus of habit L. aquatica can be viewed as a stage of perennial flower mesophyte plants’ shifting to life in water.

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Olayemi, W., O. Akapo, R. Olorunsola, A. Oso, A. Bamgbose, and A. Mafimidiwo. "Performance, Carcass Yield and Gut Microflora of Broiler Chickens Offered with Viola odorata Leaf Extract in Drinking Water." Journal of Scientific Research and Reports 13, no. 3 (January 10, 2017): 1–8. http://dx.doi.org/10.9734/jsrr/2017/31996.

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Nabiuni, Mohammad, Shirin Zeinoddini, and Hanieh Jalali. "The synergistic cytotoxic effects of doxorubicin and Viola odorata extract on human breast cancer cell line T47-D." Journal of Cancer Research and Therapeutics 15, no. 5 (2019): 1073. http://dx.doi.org/10.4103/jcrt.jcrt_990_17.

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Feyzabadi, Zohre, Fariba Ghorbani, Yasaman Vazani, and Mohammad M. Zarshenas. "A Critical Review on Phytochemistry, Pharmacology of Viola odorata L. and Related Multipotential Products in Traditional Persian Medicine." Phytotherapy Research 31, no. 11 (September 26, 2017): 1669–75. http://dx.doi.org/10.1002/ptr.5909.

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Ireland, David C., Michelle L. Colgrave, and David J. Craik. "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." Biochemical Journal 400, no. 1 (October 27, 2006): 1–12. http://dx.doi.org/10.1042/bj20060627.

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Cyclotides are a fascinating family of plant-derived peptides characterized by their head-to-tail cyclized backbone and knotted arrangement of three disulfide bonds. This conserved structural architecture, termed the CCK (cyclic cystine knot), is responsible for their exceptional resistance to thermal, chemical and enzymatic degradation. Cyclotides have a variety of biological activities, but their insecticidal activities suggest that their primary function is in plant defence. In the present study, we determined the cyclotide content of the sweet violet Viola odorata, a member of the Violaceae family. We identified 30 cyclotides from the aerial parts and roots of this plant, 13 of which are novel sequences. The new sequences provide information about the natural diversity of cyclotides and the role of particular residues in defining structure and function. As many of the biological activities of cyclotides appear to be associated with membrane interactions, we used haemolytic activity as a marker of bioactivity for a selection of the new cyclotides. The new cyclotides were tested for their ability to resist proteolysis by a range of enzymes and, in common with other cyclotides, were completely resistant to trypsin, pepsin and thermolysin. The results show that while biological activity varies with the sequence, the proteolytic stability of the framework does not, and appears to be an inherent feature of the cyclotide framework. The structure of one of the new cyclotides, cycloviolacin O14, was determined and shown to contain the CCK motif. This study confirms that cyclotides may be regarded as a natural combinatorial template that displays a variety of peptide epitopes most likely targeted to a range of plant pests and pathogens.

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Narayani, M., Anju Chadha, and Smita Srivastava. "Callus and cell suspension culture of Viola odorata as in vitro production platforms of known and novel cyclotides." Plant Cell, Tissue and Organ Culture (PCTOC) 130, no. 2 (April 26, 2017): 289–99. http://dx.doi.org/10.1007/s11240-017-1223-6.

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Mahboubi, Mohaddese, and Leila Mohammad Taghizadeh Kashani. "A Narrative study about the role of Viola odorata as traditional medicinal plant in management of respiratory problems." Advances in Integrative Medicine 5, no. 3 (December 2018): 112–18. http://dx.doi.org/10.1016/j.aimed.2017.12.003.

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Shahin, Aml A. "Effect of Natural Source as Stimulator on Vegetative Growth, Flowering, Chemical Composition and Oil on Viola Odorata, Linn." Annals of Agricultural Science, Moshtohor 59, no. 2 (April 1, 2021): 583–92. http://dx.doi.org/10.21608/assjm.2021.195391.

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Journal articles on the topic 'Viola odorata'

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