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Dissertations / Theses on the topic 'Viral tracings'

Author: Grafiati
Published: 23 September 2022
Last updated: 31 July 2025

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1

Beier, Kevin. "Viral Tracing of Neuronal Circuitry." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10241.

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To understand how the nervous system processes information, a map of the connections among neurons is essential. Viral transsynaptic transmission has gained popularity as a method for labeling neural circuits. In particular, the development of retrograde monosynaptic tracing vectors has enabled visualization of the pre-synaptic inputs onto defined sets of postsynaptic neurons. This system utilized the rabies virus (RABV), in which the glycoprotein gene in the virus was deleted, and re-supplied in trans. In order to build alternative, more flexible tracers, we made recombinant VSV genomes, firs
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2

Baba, Aïssa Hind. "Anatomie et physiologie des voies de sortie du cervelet chez le rongeur." Thesis, Université Paris sciences et lettres, 2021. http://www.theses.fr/2021UPSLE018.

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Une acquisition sensorielle et une perception précises sont des éléments clés de la survie. Bien que de nombreux paramètres sous-jacents au traitement des informations sensorielles soient connus, plusieurs aspects sont encore mal compris, comme la contribution exacte de chaque structure cérébrale. Ici, nous analysons la contribution cérébelleuse au traitement sensoriel dans le système des vibrisses de la souris. Nous identifions une projection anatomique et physiologique disynaptique des noyaux cérébelleux vers le cortex sensoriel primaire, impliquant notamment le thalamus postérieur médian (P
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3

Haberl, Matthias. "Studying Neuronal Connectivity in the Mouse Brain in Normal Condition and Fragile X Syndrome." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0480/document.

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Le but de ce travail est l'étude de la connectivité anatomique et fonctionnelle desréseaux neuronaux et le développement des nouveaux outils à cet effet. Car le dernieraspect est une préoccupation majeure de la neuroscience actuelle, nous avonsdeveloppé d'abord un nouveau traceur virale permettant la reconstruction neuronale.Nous avons ensuite appliqué cet et d'autres techniques pour sonder les défauts deconnectivité neuronale dans le syndrome de l'X fragile.Dans la première partie, nous avons discuté les avantages et inconvénients d'unetechnique émergente en utilisant un nouveau type de vecte
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4

Latham, Amity. "Tracing farmers' exploitation, alienation and agency through technology." Thesis, Federation University Australia, 2020. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/175264.

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Grain growers are caught in a system of production which is characterised by the privatisation of the farm services sector, global trade, machinery automation, and technologies. The commodity chain is structured so that costs are passed on to farmers through what they buy and sell. As a consequence of this structure, farmers are exploited and subject to the condition of alienation. Previous research has revealed the challenges of farm-scale efficiencies and the demise of rural areas due to farmer-exodus. Since Kautsky’s original publication of The Agrarian Question in 1899, there is still limi
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5

Keefe, Kathleen Mary. "In Vivo Visualization of Neural Pathways in the Rat Spinal Cord Using Viral Tracing." Diss., Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/521830.

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Neuroscience<br>Ph.D.<br>Much of our understanding of the fascinating complexity of neuronal circuits comes from anatomical tracing studies that use dyes or fluorescent markers to highlight pathways that run through the brain and spinal cord. Viral vectors have been utilized by many previous groups as tools to highlight pathways or deliver transgenes to neuronal populations to stimulate growth after injury. In a series of studies, we explore anterograde and retrograde tracing with viral vectors to trace spinal pathways and explore their contribution to behavior in a rodent model. In a separate
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6

DeBlander, Leah. "Analysis of active neural circuits and synaptic mechanisms of memory." Thesis, University of Oregon, 2018. http://hdl.handle.net/1794/23906.

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One feature of the brain is that different parts of it respond to different stimuli. This means not all brain regions or neurons within those regions are active at a given moment. This feature of the brain gives it the ability to encode and store a wide range of stimuli that are then used to make predictions about a changing external environment. Activation of non-overlapping neural populations is fundamental to the ability to encode a wide range of stimuli to represent a changing environment. To examine the limits of this idea we used genetic tools to label active cell populations following
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7

Mathews, Miranda Ann. "Electrophysiological profile and monosynaptic circuitry of efferent vestibular nucleus neurons." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/18173.

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As with other sensory modalities, the vestibular system recruits efferent circuitry to transport information from the central nervous system (CNS) to the sensory periphery. This efferent vestibular system (EVS) originates in the brainstem and terminates on vestibular hair cells and afferent fibres in the semicircular canals and otolith organs. Understanding how this central component outputs to the vestibular organs, and mediates motor and vestibular coordination, could potentially impact clinical treatment of vestibular disorders. Previous EVS work has primarily focused on the anatomy, phar
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8

Tanabe, Soshi. "Developing novel techniques for primate neural network analyses by retrograde gene transfer with viral vectors." Kyoto University, 2020. http://hdl.handle.net/2433/253133.

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9

Liu, Yang. "Neural Crosstalk Between Sympathetic Nervous System and Sensory Circuits to Brown Adipose Tissue." Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/biology_theses/44.

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Brown adipose tissue (BAT) is a critical organ for non-shivering thermogenesis, which is under control of both sympathetic and sensory neural innervation. We utilized both a retrograde sympathetic nerve tract tracer pseudorabies virus and an anterograde sensory tract tracer the H129 strain of herpes simplex virus-1 to locate individual neurons across the neuroaxis that are part of the SNS outflow from brain to interscapular BAT and are part of the sensory input to the brain. We found specific neuronal phenotype of the double-infected neurons distributed from the hindbrain to the forebrain with
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10

Prevosto, Vincent. "Sensorimotor encoding in the primate posterior parietal cortex : electrophysiological and retrograde transneuronal tracing studies." Paris 6, 2008. http://www.theses.fr/2008PA066225.

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A l’interface des systèmes sensoriels et moteurs, le cortex pariétal postérieur génère des représentations stables de l’espace, et contribue au guidage des mouvements corporels. Nous avons exploré les aires intraparietales médiale (MIP), latérale (LIP) et ventrale (VIP) par électrophysiologie et traçage transneuronal rétrograde. Nous démontrons que les informations vestibulaires de mouvement propre dans MIP viennent directement, par trois synapses, du labyrinthe. Nous décrivons aussi des bases neurales des signaux de position et de mouvement oculaire dans LIP et MIP. Dans VIP, nous montrons qu
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11

Kuramoto, Eriko. "Two types of thalamocortical projections from the motor thalamic nuclei of the rat: a single neuron tracing study using viral vectors." Kyoto University, 2009. http://hdl.handle.net/2433/124305.

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12

Nakamura, Hisashi. "Different cortical projections from three subdivisions of the rat lateral posterior thalamic nucleus: a single neuron tracing study with viral vectors." Kyoto University, 2016. http://hdl.handle.net/2433/216156.

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Final publication is available at http://dx.doi.org/10.1111/ejn.12882<br>Kyoto University (京都大学)<br>0048<br>新制・論文博士<br>博士(医学)<br>乙第13040号<br>論医博第2115号<br>新制||医||1017(附属図書館)<br>33032<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 渡邉 大, 教授 影山 龍一郎, 教授 髙橋 良輔<br>学位規則第4条第2項該当
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13

Pavlopoulos, Alexandros Ikaros. "Characterization of the synaptic connectivity patterns of genetically defined neuron types in circuits that regulate dopamine and serotonin." Thesis, KTH, Skolan för teknik och hälsa (STH), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-154201.

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The Lateral Habenula (LHb) have been implicated in both reward-seeking behavior and in depressive disorders due to its modulatory effects on dopamine rich areas. Excitatory projections from LHb target GABAergic interneurons of both ventral tegmental area (VTA) and rostromedial tegmental nucleus (RMTg) and consequently provide strong inhibition on VTA‟s dopaminergic neurons. These reward related signals are provided to LHb from distinct neuronal populations in internal Globus Pallidus (GPi). Here by using a dual viral combination of an adeno-associated helper virus (AAV) and a genetically modif
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14

Frezel, Noémie. "Modulation du traitement sensoriel par des projections descendantes directes du cortex somatosensoriel vers la moelle épinière." Thesis, Paris Sciences et Lettres (ComUE), 2019. http://www.theses.fr/2019PSLEE018.

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Les stimuli nociceptifs sont détectés par des neurones sensoriels spécialisés du système nerveux périphérique appelés nocicepteurs. L’information nociceptive est ensuite traitée dans la corne dorsale de la moelle épinière, qui contient des interneurones locaux et des neurones de projection qui envoient des axones vers le cerveau. Les aires supra-spinales projettent à leur tour vers la moelle épinière, où elles contribuent à la synchronisation des signaux nociceptifs. Une sensibilité à la douleur exagérée et anormale s'accompagne d'altérations du traitement de l’information dans la moelle épini
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15

Noftz, William Andrew. "Cholinergic Projections to the Inferior Colliculus." Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1598536937354225.

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16

Herent, Coralie. "Respiratory Adaption to Running Exercise : A Behavioral and Neuronal Circuits Study in Mice Absent Phasing of Respiratory and Locomotor Rhythms in Running Mice Control of Orienting Movements and Locomotion by Projection-Defined Subsets of Brainstem V2a Neurons Afadin Signaling at the Spinal Neuroepithelium Regulates Central Canal Formation and Gait Selection." Thesis, université Paris-Saclay, 2021. http://www.theses.fr/2021UPASL001.

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Pendant la course, la ventilation augmente pour compenser la demande énergétique accrue. Le substrat, soupçonné neuronal, de cette hyperpnée à l'exercice est néanmoins toujours méconnu. Pour le caractériser, nous avons, chez la souris, examiné les interactions entre i) mouvements des membres et cycles respiratoires, et ii) réseaux neuronaux locomoteur et respiratoire. Tout d’abord, en combinant enregistrements électromyographiques (EMG) du diaphragme combinés au suivi vidéo des membres pendant la course, nous montrons que, pour une large gamme de vitesses sur un tapis roulant, la fréquence res
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17

Rasteiro, Ana Beatriz de Almeida. "Alveolar Macrophages in Pulmonary Neuro-immune Communication." Master's thesis, 2019. http://hdl.handle.net/10362/89614.

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Alveolar macrophages are strategically located at the lung mucosal surface and are part of an intricate cellular network. Here, immune cells, epithelial cells and neurons functionally interact to maintain homeostasis despite a multitude of aggressions and ever-changing environmental conditions. Previous evidence suggest that neuron-derived cues may modulate alveolar macrophages, but also indicate that immune cells influence neuronal activity. Thus, we hypothesized that alveolar macrophages functionally interact with neurons in so-called neuro-immune cell units. Nevertheless, the identity of th
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18

Carvalho, Daniela Brum de. "Organization of the precise connectivity between mouse basomedial amygdala and insular cortex." Master's thesis, 2018. http://hdl.handle.net/10316/86148.

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Dissertação de Mestrado em Biologia Celular e Molecular apresentada à Faculdade de Ciências e Tecnologia<br>Estudos recentes têm indicado que o córtex da insula (IC) é uma região cerebral com um papel preponderante no processamento de emoções, incluindo medo e ansiedade. Acredita-se que esta e outras funções, tais como aprendizagem de sinais que transmitem segurança, previsão de risco e antecipação, são executadas juntamente com a amígdala, uma área que, tal como o IC, se encontra também desregulada em distúrbios de ansiedade. Esta hipótese é também suportada por evidências de estudos convenci
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