Relevant bibliographies by topics / Virus de la dengue

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  1. Dissertations / Theses

Academic literature on the topic 'Virus de la dengue'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 October 2024

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Dissertations / Theses on the topic "Virus de la dengue"

1

Tiew, Kok-Chuan. "Dengue virus protease inhibitors." Thesis, Wichita State University, 2011. http://hdl.handle.net/10057/6117.

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Dengue virus (DENV) is a major health threat that affects 2.5 billion people, or 40% of the world’s population. However, there are no approved antiviral drugs or vaccines to treat Dengue infection. This thesis describes the design, synthesis and discovery of a new class of inhibitors of DENV NS3 protease. Structure-activity relationship studies have been carried out in order to delineate the structural elements responsible for the activity of this series of compounds. A lead compound suitable for further development has been identified.<br>Thesis (M.S.)--Wichita State University, College of Li
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2

Aravapalli, Sridhar. "Dengue virus and West Nile virus protease inhibitors." Diss., Wichita State University, 2013. http://hdl.handle.net/10057/6719.

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Dengue virus and West Nile virus are important mosquito-borne pathogens of Flaviviridae family affecting millions of people worldwide and causing a severe global healthcare threat. However, currently there are no approved effective antiviral drugs or vaccines available for the treatment of virus infection. This thesis describes the design, synthesis and discovery of two novel classes of reversible competitive inhibitors of Dengue Virus and West Nile Virus NS2B/NS3 protease. Structure-activity relationship studies have led to the identification of a low micromolar hit, which will be used in a h
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3

Tran, Tuan Anh. "Screening against the dengue virus polymerase." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4006.

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La dengue, une des maladies les plus largement émergents actuellement, avec 390 millions d'infections chaque année (OMS), est causée par le virus de la dengue contre lequel il n’existe pas de traitements. La protéine NS5 a un rôle important dans le cycle de réplication. Cette protéine se compose d'une méthionine S-transférase d’adénosyl en N-terminal et une ARN polymérase dépendante de l'ARN (RdRp) en C-terminal. Cette NS5 RdRp peut catalyser non seulement la synthèse du brin négatif de l'ARN, utilisé comme matrice pour synthétiser l'ARN brin plus-supplémentaire, mais aussi pour la synthèse d'
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4

He, Runtao. "Characterization of dengue virus envelope protein." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq24745.pdf.

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5

Schaar, Hilde van der. "Cell entry mechanisms of dengue virus." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2009. http://irs.ub.rug.nl/ppn/318.

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6

Thu, Hlaing Myat. "Virus diversity and the emergence of Dengue." Thesis, Queensland University of Technology, 2004. https://eprints.qut.edu.au/16081/1/Hlaing_Myat_Thu_Thesis.pdf.

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The aims of this study were to investigate the role of the diversity of dengue virus populations in changing patterns of virus transmission and disease. Prior to the commencement of this study, dengue 2 virus (DENV-2) had been associated most frequently with severe disease, so the study commenced with this serotype. Because it was not possible to quantitate diversity in the entire 11 kb of the viral genome, the study focussed on the envelope (E) gene, because the E protein is the major protein on the surface of the virion and thus might be under strong selective pressure from the host immune s
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7

Thu, Hlaing Myat. "Virus Diversity and the Emergence of Dengue." Queensland University of Technology, 2004. http://eprints.qut.edu.au/16081/.

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The aims of this study were to investigate the role of the diversity of dengue virus populations in changing patterns of virus transmission and disease. Prior to the commencement of this study, dengue 2 virus (DENV-2) had been associated most frequently with severe disease, so the study commenced with this serotype. Because it was not possible to quantitate diversity in the entire 11 kb of the viral genome, the study focussed on the envelope (E) gene, because the E protein is the major protein on the surface of the virion and thus might be under strong selective pressure from the host immune s
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8

Lindegren, Gunnel. "Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis." Stockholm : Department of Microbiology, Karolinska Institutet, 2008. http://diss.kib.ki.se/2008/978-91-7409-129-8/.

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9

Niberon, Yann. "Hyperspectral Plasmonic Biosensor for Dengue Virus Detection." Electronic Thesis or Diss., Troyes, 2021. http://www.theses.fr/2021TROY0041.

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La résonance des plasmons de surface (SPR en anglais) est une technique utilisée pour détecter certaines liaisons chimiques spécifiques et leurs évolutions dans le temps avec une sensibilité et une spécificité élevée. L’objectif de ce projet est de proposer un biocapteur SPR en hyperspectral et compact pour détecter le virus de la dengue. Basé sur un système statique avec des réflexions sur des surfaces paraboliques et utilisant une source de lumière blanche, dans la configuration de Kretschmann il a été possible de réaliser simultanément une interrogation angulaire et spectrale pour générer u
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10

Tison, Laurence. "La dengue." Bordeaux 2, 1995. http://www.theses.fr/1995BOR2P091.

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