Log in

Relevant bibliographies by topics / Virus particle assembly

Contents

Journal articles
Dissertations / Theses
Books
Book chapters
Conference papers
Reports

Academic literature on the topic 'Virus particle assembly'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Virus particle assembly.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Virus particle assembly"

1

Crist, Rachael M., Siddhartha A. K. Datta, Andrew G. Stephen, et al. "Assembly Properties of Human Immunodeficiency Virus Type 1 Gag-Leucine Zipper Chimeras: Implications for Retrovirus Assembly." Journal of Virology 83, no. 5 (2008): 2216–25. http://dx.doi.org/10.1128/jvi.02031-08.

Full text

Abstract:

ABSTRACT Expression of the retroviral Gag protein leads to formation of virus-like particles in mammalian cells. In vitro and in vivo experiments show that nucleic acid is also required for particle assembly. However, several studies have demonstrated that chimeric proteins in which the nucleocapsid domain of Gag is replaced by a leucine zipper motif can also assemble efficiently in mammalian cells. We have now analyzed assembly by chimeric proteins in which nucleocapsid of human immunodeficiency virus type 1 (HIV-1) Gag is replaced by either a dimerizing or a trimerizing zipper. Both proteins

APA, Harvard, Vancouver, ISO, and other styles

2

Wang, Shainn-Wei, and Anna Aldovini. "RNA Incorporation Is Critical for Retroviral Particle Integrity after Cell Membrane Assembly of Gag Complexes." Journal of Virology 76, no. 23 (2002): 11853–65. http://dx.doi.org/10.1128/jvi.76.23.11853-11865.2002.

Full text

Abstract:

ABSTRACT The nucleocapsid (NC) domain of retroviruses plays a critical role in specific viral RNA packaging and virus assembly. RNA is thought to facilitate viral particle assembly, but the results described here with NC mutants indicate that it also plays a critical role in particle integrity. We investigated the assembly and integrity of particles produced by the human immunodeficiency virus type 1 M1-2/BR mutant virus, in which 10 of the 13 positive residues of NC have been replaced with alanines and incorporation of viral genomic RNA is virtually abolished. We found that the mutations in t

APA, Harvard, Vancouver, ISO, and other styles

3

Chlanda, Petr, Oliver Schraidt, Susann Kummer, et al. "Structural Analysis of the Roles of Influenza A Virus Membrane-Associated Proteins in Assembly and Morphology." Journal of Virology 89, no. 17 (2015): 8957–66. http://dx.doi.org/10.1128/jvi.00592-15.

Full text

Abstract:

ABSTRACTThe assembly of influenza A virus at the plasma membrane of infected cells leads to release of enveloped virions that are typically round in tissue culture-adapted strains but filamentous in strains isolated from patients. The viral proteins hemagglutinin (HA), neuraminidase (NA), matrix protein 1 (M1), and M2 ion channel all contribute to virus assembly. When expressed individually or in combination in cells, they can all, under certain conditions, mediate release of membrane-enveloped particles, but their relative roles in virus assembly, release, and morphology remain unclear. To in

APA, Harvard, Vancouver, ISO, and other styles

4

Wang, Chin-Tien, Hsiu-Yu Lai, and Jue-Jyh Li. "Analysis of Minimal Human Immunodeficiency Virus Type 1 gag Coding Sequences Capable of Virus-Like Particle Assembly and Release." Journal of Virology 72, no. 10 (1998): 7950–59. http://dx.doi.org/10.1128/jvi.72.10.7950-7959.1998.

Full text

Abstract:

ABSTRACT We have constructed a series of human immunodeficiency virus (HIV)gag mutants by progressive truncation of thegag coding sequence from the C terminus and have combined these mutants with an assembly-competent matrix domain deletion mutation (ΔMA). By using several methods, the particle-producing capabilities of each mutant were examined. Our analysis indicated that truncated Gag precursors lacking most of C-terminal gaggene products assembled and were released from 293T cells. Additionally, a mutant with a combined deletion of the MA (ΔMA) and p6 domains even produced particles at lev

APA, Harvard, Vancouver, ISO, and other styles

5

Joshi, Swati M., and Volker M. Vogt. "Role of the Rous Sarcoma Virus p10 Domain in Shape Determination of Gag Virus-Like Particles Assembled In Vitro and within Escherichia coli." Journal of Virology 74, no. 21 (2000): 10260–68. http://dx.doi.org/10.1128/jvi.74.21.10260-10268.2000.

Full text

Abstract:

ABSTRACT Purified retrovirus Gag proteins can assemble in vitro into virus-like particles (VLPs) in the presence of RNA. It was shown previously that a Rous sarcoma virus Gag protein missing only the protease domain forms spherical particles resembling immature virions lacking a membrane but that a similar protein missing the p10 domain forms tubular particles. Thus, p10 plays a role in spherical particle formation. To further study this shape-determining function, we dissected the p10 domain by mutagenesis and examined VLPs assembled within Escherichia coli or assembled in vitro from purified

APA, Harvard, Vancouver, ISO, and other styles

6

Gómez-Puertas, Paulino, Carmen Albo, Esperanza Pérez-Pastrana, Amparo Vivo, and Agustı́n Portela. "Influenza Virus Matrix Protein Is the Major Driving Force in Virus Budding." Journal of Virology 74, no. 24 (2000): 11538–47. http://dx.doi.org/10.1128/jvi.74.24.11538-11547.2000.

Full text

Abstract:

ABSTRACT To get insights into the role played by each of the influenza A virus polypeptides in morphogenesis and virus particle assembly, the generation of virus-like particles (VLPs) has been examined in COS-1 cell cultures expressing, from recombinant plasmids, different combinations of the viral structural proteins. The presence of VLPs was examined biochemically, following centrifugation of the supernatants collected from transfected cells through sucrose cushions and immunoblotting, and by electron-microscopic analysis. It is demonstrated that the matrix (M1) protein is the only viral com

APA, Harvard, Vancouver, ISO, and other styles

7

Tellinghuisen, Timothy L., and Richard J. Kuhn. "Nucleic Acid-Dependent Cross-Linking of the Nucleocapsid Protein of Sindbis Virus." Journal of Virology 74, no. 9 (2000): 4302–9. http://dx.doi.org/10.1128/jvi.74.9.4302-4309.2000.

Full text

Abstract:

ABSTRACT The assembly of the alphavirus nucleocapsid core is a multistep event requiring the association of the nucleocapsid protein with nucleic acid and the subsequent oligomerization of capsid proteins into an assembled core particle. Although the mechanism of assembly has been investigated extensively both in vivo and in vitro, no intermediates in the core assembly pathway have been identified. Through the use of both truncated and mutant Sindbis virus nucleocapsid proteins and a variety of cross-linking reagents, a possible nucleic acid-protein assembly intermediate has been detected. The

APA, Harvard, Vancouver, ISO, and other styles

8

Yuste-Calvo, Carmen, Pablo Ibort, Flora Sánchez, and Fernando Ponz. "Turnip Mosaic Virus Coat Protein Deletion Mutants Allow Defining Dispensable Protein Domains for ‘in Planta’ eVLP Formation." Viruses 12, no. 6 (2020): 661. http://dx.doi.org/10.3390/v12060661.

Full text

Abstract:

The involvement of different structural domains of the coat protein (CP) of turnip mosaic virus, a potyvirus, in establishing and/or maintaining particle assembly was analyzed through deletion mutants of the protein. In order to identify exclusively those domains involved in protein–protein interactions within the particle, the analysis was performed by agroinfiltration “in planta”, followed by the assessment of CP accumulation in leaves and the assembly of virus-like particles lacking nucleic acids, also known as empty virus-like particles (eVLP). Thus, the interactions involving viral RNA co

APA, Harvard, Vancouver, ISO, and other styles

9

Campbell, Stephen, and Alan Rein. "In Vitro Assembly Properties of Human Immunodeficiency Virus Type 1 Gag Protein Lacking the p6 Domain." Journal of Virology 73, no. 3 (1999): 2270–79. http://dx.doi.org/10.1128/jvi.73.3.2270-2279.1999.

Full text

Abstract:

ABSTRACT Human immunodeficiency virus type 1 (HIV-1) normally assembles into particles of 100 to 120 nm in diameter by budding through the plasma membrane of the cell. The Gag polyprotein is the only viral protein that is required for the formation of these particles. We have used an in vitro assembly system to examine the assembly properties of purified, recombinant HIV-1 Gag protein and of Gag missing the C-terminal p6 domain (Gag Δp6). This system was used previously to show that the CA-NC fragment of HIV-1 Gag assembled into cylindrical particles. We now report that both HIV-1 Gag and Gag

APA, Harvard, Vancouver, ISO, and other styles

10

Moraleda, Gloria, Steven Seeholzer, Vadim Bichko, Roland Dunbrack, James Otto, and John Taylor. "Unique Properties of the Large Antigen of Hepatitis Delta Virus." Journal of Virology 73, no. 9 (1999): 7147–52. http://dx.doi.org/10.1128/jvi.73.9.7147-7152.1999.

Full text

Abstract:

ABSTRACT The large form of the hepatitis delta virus (HDV) protein (L) can be isoprenylated near its C terminus, and this modification is considered essential for particle assembly. Using gel electrophoresis, we separated L into two species of similar mobilities. The slower species could be labeled by the incorporation of [14C]mevalonolactone and is interpreted to be isoprenylated L (Li). In serum particles, infected liver, transfected cells, and assembled particles, 25 to 85% of L was isoprenylated. Isoprenylation was also demonstrated by 14C incorporation in vitro with a rabbit reticulocyte

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Virus particle assembly"

1

Isherwood, Beverley Jane. "Hepatitis C virus : particle assembly and morphogenesis." Thesis, University of Glasgow, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410179.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Soh, Timothy Kinshiong. "Single particle studies of vesicular stomatitis virus assembly." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17464089.

Full text

Abstract:

The formation of viral particles requires the coordinated assembly of both nucleic acids and proteins. In the case of Rhabdoviruses, such as vesicular stomatitis virus (VSV), the particles display a characteristic bullet-shape. VSV virions consist of the matrix protein (M), glycoprotein (G), and viral ribonucleoprotein (RNP), which contains the nucleocapsid protein (N) coated RNA bound to the large polymerase protein (L) through the phosphoprotein (P). During assembly, these components are recruited to the plasma membrane where the viral RNP undergoes condensation by M and envelopment with G c

APA, Harvard, Vancouver, ISO, and other styles

3

Höfer, Chris Tina. "Influenza virus assembly." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2015. http://dx.doi.org/10.18452/17251.

Full text

Abstract:

Influenza A Viren besitzen ein segmentiertes, einzelsträngiges RNA-Genom, welches in Form viraler Ribonukleoprotein (vRNP)-Komplexe verpackt ist. Während das virale Genom im Zellkern repliziert wird, finden Assemblierung und Knospung reifer Viruspartikel an der apikalen Plasmamembran statt. Für die Virusbildung müssen die einzelnen viralen Komponenten hierher gebracht werden. Während intrinsische apikale Signale der viralen Transmembranproteine bekannt sind, sind der zielgerichtete Transport und der Einbau des viralen Genoms in neuentstehende Virionen noch wenig verstanden. In dieser Arbeit wu

APA, Harvard, Vancouver, ISO, and other styles

4

Ziegler, Christopher Michael. "Key Virus-Host Interactions Required For Arenavirus Particle Assembly And Release." ScholarWorks @ UVM, 2017. http://scholarworks.uvm.edu/graddis/755.

Full text

Abstract:

Viruses are infectious agents that must infect the cells of living organisms in order to reproduce. They have relatively simple genomes which encode few proteins but can compensate for their simplicity by hijacking components of their cellular hosts. Arenaviruses, a family of zoonotic viruses carried by rodents, encode only 4 proteins. One of these proteins, Z, is responsible for several functions during the virus life cycle including driving the formation and release of new virus particles at the plasma membrane of infected cells. Relatively little is known about how this viral protein is reg

APA, Harvard, Vancouver, ISO, and other styles

5

Corless, Lynsey. "The role of the host ESCRT complex in hepatitis C virus particle assembly and release." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530841.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Hughes, Mair Elisabeth. "Identification of residues in hepatitis C virus NS5A with a critical role in genome replication of particle assembly." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531528.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Kern, Anika [Verfasser], and Karl Klaus [Akademischer Betreuer] Conzelmann. "Assembly and budding of Rabies Virus : the phosphoprotein as critical determinant of particle production / Anika Kern. Betreuer: Karl Klaus Conzelmann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/1031381120/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Kern, Anika [Verfasser], and Karl-Klaus [Akademischer Betreuer] Conzelmann. "Assembly and Budding of Rabies Virus : The Phosphoprotein as Critical Determinant of Particle Production / Anika Kern. Betreuer: Karl-Klaus Conzelmann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/102366092X/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Boyer, Audrey. "Caractérisation de mécanismes mis en jeu lors des étapes précoces de l'assemblage des lipoviroparticules du virus de l'hépatite C." Thesis, Tours, 2015. http://www.theses.fr/2015TOUR3308/document.

Full text

Abstract:

Lors d’une infection chronique, le virus de l'hépatite C (HCV) circule sous forme de lipoviroparticule (LVP) : particules hybrides associant des composants viraux (ARN, les protéines structurelles) et des composants cellulaires (apolipoprotéines, cholestérol). Au cours de ma thèse, nous nous sommes intéressés à identifier la plateforme d'assemblage du HCV, et le rôle du rassemblement des protéines virales par NS2 dans sa formation. Nous avons montré que des interactions de natures différentes sur la membrane du RE sont impliquées dans cette association protéique. Nos résultats suggèrent que de

APA, Harvard, Vancouver, ISO, and other styles

10

Bouter, Caroline [Verfasser], Frank Torsten [Akademischer Betreuer] Hufert, and Detlef [Akademischer Betreuer] Doenecke. "The Role of NS3 Helicase Domain in Hepatitis C Virus Particle Assembly / Caroline Bouter. Gutachter: Frank Torsten Hufert ; Detlef Doenecke. Betreuer: Frank Torsten Hufert." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044869844/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Books on the topic "Virus particle assembly"

1

Adamson, Catherine Sarah. An analysis of the TY1 virus-like particle: Assembly and interaction witht he host microtubule network. University of Manchester, 1997.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

2

Sherwood, Dennis, and Paul Dalby. Thermodynamics today – and tomorrow. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198782957.003.0026.

Full text

Abstract:

This last chapter explores the frontiers of how thermodynamics is currently being applied to biology, moving from the scale of the molecule to the scale of the cell. The key theme is ‘self-assembly’ – the process by which macromolecules spontaneously assemble into larger structures such as cell membranes, cell organelles, cells, and ultimately organisms. The starting point is the simplest process of self-assembly, the formation of a liquid from the condensation of a gas, which draws on some results from Chapter 15, and develops the concept of nucleation, this leads to a discussion of protein a

APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Virus particle assembly"

1

Lee, L. Andrew, Elizabeth Balizan, Yuan Lin, and Qian Wang. "Assembly of Virus Particles and Virus-like Particles as Templates for Biomedical Applications." In ACS Symposium Series. American Chemical Society, 2012. http://dx.doi.org/10.1021/bk-2012-1119.ch002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Dekhtyar, Yu, Anna Kachanovska, G. Mezinskis, A. Patmalnieks, P. Pumpens, and R. Renhofa. "Self — Assembled System: Semiconductor and Virus Like Particles." In IFMBE Proceedings. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-69367-3_163.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Dobrica, Mihaela-Olivia, Catalin Lazar, and Norica Branza-Nichita. "Production of Chimeric Hepatitis B Virus Surface Antigens in Mammalian Cells." In Vaccine Delivery Technology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0795-4_7.

Full text

Abstract:

Abstract The small (S) envelope protein of the Hepatitis B Virus (HBV), HBV-S, has the unique ability to self-assemble into highly immunogenic subviral particles (SVPs), in the absence of other viral factors, in eukaryotic cells, including those of nonhepatic origin. This feature is currently exploited for generation of SVPs exposing heterologous epitopes on their surface that can be used as vaccine candidates to target various diseases. Here, we describe a simple and robust method for production of such chimeric HBV-S protein-based SVPs in transiently transfected HEK293T cells and purification from cell supernatants by ultracentrifugation on sucrose cushion and sucrose step gradients. The SVPs obtained by this methodology have been successfully used in immunogenicity studies in animal models.

APA, Harvard, Vancouver, ISO, and other styles

4

Hwang, D. J., I. M. Roberts, and T. M. A. Wilson. "Assembly of tobacco mosaic virus and TMV-like pseudovirus particles in Escherichia coli." In Positive-Strand RNA Viruses. Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9326-6_52.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Datta, Siddhartha A. K., and Alan Rein. "Preparation of Recombinant HIV-1 Gag Protein and Assembly of Virus-Like Particles In Vitro." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-170-3_14.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Snippe, Marjolein, Rob Goldbach, and Richard Kormelink. "Tomato Spotted Wilt Virus Particle Assembly and the Prospects of Fluorescence Microscopy to Study Protein–protein Interactions Involved." In Advances in Virus Research. Elsevier, 2005. http://dx.doi.org/10.1016/s0065-3527(05)65003-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

"Assembly of a Bluetongue Virus-Like Particle: Multiprotein Complex and Its Use as Vaccine." In Viral Nanotechnology. CRC Press, 2015. http://dx.doi.org/10.1201/b18596-23.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Jeffery-Smith, Anna, and C. Y. William Tong. "The Biology of Viruses." In Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0008.

Full text

Abstract:

In order to be classified as a virus, certain criteria have to be fulfilled. Viruses must ● Be only capable of growth and multiplication within living cells, i.e. obligate intracellular parasite. Host cells could include humans, animals, insects, plants, protozoa, or even bacteria. ● Have a nucleic acid genome (either RNA or DNA, but not both) surrounded by a protein coat (capsid). ● Have no semipermeable membrane, though some have an envelope formed of phospholipids and proteins. ● Be inert outside of the host cell. Enveloped viruses are susceptible to inactivation by organic solvents such as alcohol. ● Perform replication by independent synthesis of components followed by assembly (c.f. binary fission in bacteria). Viruses are considered as a bundle of genetic programmes encoded in nucleic acids and packaged with a capsid +/ - envelope protein, which can be activated on entry into a host cell (compare this with computer viruses packaged in an enticing way in order to infect and take over control of your PC). Although they share some similarities in their properties, mycoplasma and chlamydia are true bacteria. The virion (assembled infectious particle) consists of viral nucleic acid and capsid. The nucleic acid of a virus can either be ribonucleic acid (RNA) or deoxyribonucleic acid (DNA), and the amount of genetic material varies widely, with some viruses able to encode a few proteins and others having genetic material that encodes hundreds of proteins. In association with the nucleic acid there may be non- structural viral proteins, such as a viral polymerase. The nucleic acid and non- structural proteins are protected by a surrounding layer of capsid proteins. The capsid includes proteins which can attach to host cell receptors. The proteins and the cell receptors to which they bind determine a virus’ tropism, i.e., the ability to bind to and enter different cell types. The term nucleocapsid refers to the nucleic acid core surrounded by capsid protein. Some viruses also have an envelope made up of phospholipids and proteins surrounding the nucleocapsid. This envelope can be formed by the host cell membrane during the process of a virus budding from a cell during replication.

APA, Harvard, Vancouver, ISO, and other styles

9

Hull, Roger. "Architecture and Assembly of Virus Particles." In Matthews' Plant Virology. Elsevier, 2002. http://dx.doi.org/10.1016/b978-012361160-4/50056-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Hull, Roger. "Architecture and Assembly of Virus Particles." In Plant Virology. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-384871-0.00003-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Virus particle assembly"

1

Lipin, Daniel, Yap Chuan, Marcus Neibert, Yuan Fan, and Anton Middelberg. "Processing and in vitro Assembly of Virus Like Particle Nanostructures." In 2006 International Conference on Nanoscience and Nanotechnology. IEEE, 2006. http://dx.doi.org/10.1109/iconn.2006.340590.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Virus particle assembly"

1

Douglas, Trevor. Self-Assembly of Virus Particle Based Materials for Hydrogen Catalysis. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1722913.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!