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Journal articles on the topic 'Virus SARS-CoV-2'

Author: Grafiati

Published: 14 September 2024

Last updated: 31 July 2025

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1

Italo, Giuffre. "Sars-Cov-2 Virus and Eye." Open Access Journal of Ophthalmology 7, no. 1 (2022): 1–2. http://dx.doi.org/10.23880/oajo-16000238.

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It is a minireview about the impact of SARS COVID-19 pandemia on Ophthalmology. Since 1990’s this virus was studied and some researchers showed its retinotropism. Nowadays, according to the World Health Organization guidelines, we explain how Italian ophthalmologist and nurses faced the effect of this pandemia on our daily work.

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Sequera, Guillermo. "SARS-Cov 2, a virus for rheumatologists." Revista Paraguaya de Reumatología 6, no. 2 (2020): 48–49. http://dx.doi.org/10.18004/rpr/2020.06.02.48.

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Kaptan, Figen. "SARS-CoV-2 ve İnfluenza Virüs Birlikteliği." Flora the Journal of Infectious Diseases and Clinical Microbiology 25, no. 4 (2020): 457–63. http://dx.doi.org/10.5578/flora.70015.

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Severe acute respiratory syndrome virus 2 was initially identified in the Chinese city Wuhan on 29 December 2019. The infection has rapidly spread all over the world, and the World Health Organization declared the infection a pandemic on 11 March 2020. The disease, named coronavirus disease 19, has similar modes of transmission and clinical features with influenza, and coinfections have also been reported during the course of coronavirus disease 19. Studies have shown that the ratio of coinfections ranged widely among studies, and the clinical presentation in coinfections has varied from mild

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Satoru, Nakamura Kawatana Medical Center Japan. "Current Research Status of SARS-CoV-2 as a Pathogen of COVID-19." Journal of Health and Medical Sciences 3, no. 2 (2020): 184. https://doi.org/10.31014/aior.1994.03.02.113.

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COVID-19 was first identified in an outbreak in Wuhan, China, in December 2019. COVID-19 is defined as Corona Virus Infectious Disease 2019, and it’s caused by SARS (severe acute respiratory syndrome)-CoV (coronavirus)-2. This article shows the current research status on SARS-CoV-2.

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Vodolazhskiy, D. I. "POTENTIAL ONCOGENICITY OF SARS-COV-2 VIRUS." Современные проблемы науки и образования (Modern Problems of Science and Education), no. 4 2022 (2022): 76. http://dx.doi.org/10.17513/spno.31864.

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Maroto Vela, María del Carmen. "SARS-CoV-2: Problems and uncertainties." ANALES RANM 137, no. 137(02) (2020): 98–103. http://dx.doi.org/10.32440/ar.2020.137.02.rev01.

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Heinz, Franz X., and Karin Stiasny. "Profile of SARS-CoV-2." Wiener klinische Wochenschrift 132, no. 21-22 (2020): 635–44. http://dx.doi.org/10.1007/s00508-020-01763-1.

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SummaryThe recent emergence of a new coronavirus (severe acute respiratory syndrome coronavirus‑2, SARS-CoV-2) that is transmitted efficiently among humans and can result in serious disease and/or death has become a global threat to public health and economy. In this article, we describe some of the most important characteristics of this new virus (including gaps in our understanding) and provide a perspective of ongoing activities for developing virus-specific countermeasures, such as vaccines and antiviral drugs.

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Burić, Nina, and Simona Stojanović. "Occupational hazard for Dental staff exposed to the SARS-CoV-2 virus during Dental procedures." Acta stomatologica Naissi 36, no. 81 (2020): 1995–2006. http://dx.doi.org/10.5937/asn2081995b.

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Introduction: The dental profession is a high-risk profession, considering the aspect of a possible 100% infection from patients who are carriers of bacterial, viral and fungal diseases during dental interventions. Aim: To perform the analysis of all data that explain the possibility of a SARS-CoV-2 virus infection in dental practice. Material and Methods: The literature data on the presence of SARS-CoV-2 virus, and its characteristics and behavior in the external environment and in living tissues was analyzed. Databases from the Medline, Cochrane Library, Science-Direct, EMBASE, and Google sc

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Polz-Dacewicz, Małgorzata. "Novel coronavirus – SARS CoV-2." Polish Journal of Public Health 129, no. 4 (2019): 113–17. http://dx.doi.org/10.2478/pjph-2019-0026.

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AbstractCoronaviruses cause a variety of diseases in mammals and birds. In late December, 2019, patients presenting with viral pneumonia due to an unidentified microbial agent were reported in Wuhan, China. A novel coronavirus was subsequently identified as the causative pathogen, provisionally named 2019 novel coronavirus (2019-nCoV). This virus appears to be a new human pathogen. In this article the biology of virus has been described, replication cycle and epidemiology of COVID 19. The next part discusses current methods of laboratory diagnostics. The coronavirus disease 2019 (COVID-19) pan

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Gorkhali, Ritesh, Prashanna Koirala, Sadikshya Rijal, Ashmita Mainali, Adesh Baral, and Hitesh Kumar Bhattarai. "Structure and Function of Major SARS-CoV-2 and SARS-CoV Proteins." Bioinformatics and Biology Insights 15 (January 2021): 117793222110258. http://dx.doi.org/10.1177/11779322211025876.

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SARS-CoV-2 virus, the causative agent of COVID-19 pandemic, has a genomic organization consisting of 16 nonstructural proteins (nsps), 4 structural proteins, and 9 accessory proteins. Relative of SARS-CoV-2, SARS-CoV, has genomic organization, which is very similar. In this article, the function and structure of the proteins of SARS-CoV-2 and SARS-CoV are described in great detail. The nsps are expressed as a single or two polyproteins, which are then cleaved into individual proteins using two proteases of the virus, a chymotrypsin-like protease and a papain-like protease. The released protein

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Sánchez-Cárdenas, Mayté, Bárbara Toledo-Pimentel, Yanira Zaita-Ferrer, and Rigoberto Fimia-Duarte. "VIRUS SARS-CoV-2 Y PERIODONTITIS." Paideia XXI 11, no. 1 (2021): 247–54. http://dx.doi.org/10.31381/paideia.v11i1.3720.

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Diversos artículos científicos han propuesto hipótesis para asociar la enfermedad producida por el virus del SARS-CoV-2 con la periodontitis. Adentrarse en los posibles factores e indicadores de riesgo constituyen elementos esenciales para comprender el papel del virus en la patogenia de la periodontitis, indican la necesidad de un trabajo mancomunado de médicos y periodontólogos en el protocolo de prevención y control de la COVID-19. Se considera que la relación entre estas enfermedades es bidireccional, el efecto del virus en el sistema inmunológico puede agravar la periodontitis y por otro

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Halpert, Gilad, and Yehuda Shoenfeld. "SARS-CoV-2, the autoimmune virus." Autoimmunity Reviews 19, no. 12 (2020): 102695. http://dx.doi.org/10.1016/j.autrev.2020.102695.

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Liu, Yawen, and Jianhui Nie. "SARS-CoV-2-Neutralizing Antibodies." Vaccines 12, no. 11 (2024): 1256. http://dx.doi.org/10.3390/vaccines12111256.

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Bojkova, Denisa, Jake E. McGreig, Katie-May McLaughlin, et al. "Differentially conserved amino acid positions may reflect differences in SARS-CoV-2 and SARS-CoV behaviour." Bioinformatics 37, no. 16 (2021): 2282–88. http://dx.doi.org/10.1093/bioinformatics/btab094.

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Abstract Motivation SARS-CoV-2 is a novel coronavirus currently causing a pandemic. Here, we performed a combined in-silico and cell culture comparison of SARS-CoV-2 and the closely related SARS-CoV. Results Many amino acid positions are differentially conserved between SARS-CoV-2 and SARS-CoV, which reflects the discrepancies in virus behaviour, i.e. more effective human-to-human transmission of SARS-CoV-2 and higher mortality associated with SARS-CoV. Variations in the S protein (mediates virus entry) were associated with differences in its interaction with ACE2 (cellular S receptor) and sen

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Bakhat, Shaista, and Yasmeen Taj. "Characteristic Features of SARS CoV-2." Journal of Bahria University Medical and Dental College 11, no. 03 (2021): 129–35. http://dx.doi.org/10.51985/fnwg4302.

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Corona-virus arose from China, spread globally and has become a great challenge for health care workers and Governments of several countries. This virus is transmitted predominately through respiratory droplets by symptomatic and asymptomatic carriers. The disease manifests itself with fever, dry cough and shortness of breath, these symptoms may be mild or have fatal outcomes. This virus attaches to the angiotensin converting enzyme (ACE) receptor, in the lung. This assessment, recapitulates the existing awareness of host features and the paths that are activated with HCOV (Human Corona virus)

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Rahimlou, Bahman, Niki Ghanbari Mohammadi, Rasoul Rashidi, and Sara Ghaffarpour. "Immune System Vs. SARS-CoV-2." Immunoregulation 5, no. 1 (2022): 3–14. http://dx.doi.org/10.32598/immunoregulation.5.1.7.

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In 2019, the SARS-CoV-2 virus caused one of the biggest virus pandemics called Coronavirus disease-19 (COVID-19). This virus has been responsible for the death of millions of people around the world. The biological function of SARS-CoV-2 and its pathophysiology mechanisms, as well as the host immunity against this virus, has attracted the attention of the scientific community all over the world. The current study reviewed innate and acquired immune responses following COVID-19 infection. These immune responses are probably involved in the severity of the disease and death. Also, the cause and

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Bojkova, Denisa, Marco Bechtel, Katie-May McLaughlin, et al. "Aprotinin Inhibits SARS-CoV-2 Replication." Cells 9, no. 11 (2020): 2377. http://dx.doi.org/10.3390/cells9112377.

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Severe acute respiratory syndrome virus 2 (SARS-CoV-2) is the cause of the current coronavirus disease 19 (COVID-19) pandemic. Protease inhibitors are under consideration as virus entry inhibitors that prevent the cleavage of the coronavirus spike (S) protein by cellular proteases. Herein, we showed that the protease inhibitor aprotinin (but not the protease inhibitor SERPINA1/alpha-1 antitrypsin) inhibited SARS-CoV-2 replication in therapeutically achievable concentrations. An analysis of proteomics and translatome data indicated that SARS-CoV-2 replication is associated with a downregulation

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18

Berche, Patrick. "Les variants SARS-CoV-2." Revue de biologie médicale 361, no. 4 (2021): 13–21. https://doi.org/10.3917/rbm.361.0013.

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Comme beaucoup d’autres virus à ARN, le coronavirus SARS-CoV-2 évolue par de multiples mutations au cours du temps. Ces mutations sont liées à des erreurs de lecture de l’ARN polymérase virale. La plupart sont silencieuses, c’est-à-dire qu’elles ne modifient pas ou peu la séquence peptidique des protéines et n’ont aucune conséquence virale. Cependant, certains mutants, surnommés « variants of concern », peuvent changer la structure tridimensionnelle de protéines impliquées dans la contagiosité ou la pathogénicité des virus. Cela concerne notamment de la protéine S (Spike) qui, en interagissant

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Silva O., Francisco, and Marcela Cifuentes D. "Retrato microbiológico SARS-CoV-2." Revista Hospital Clínico Universidad de Chile 31, no. 2 (2020): 109–10. http://dx.doi.org/10.5354/2735-7996.2020.69902.

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SARS-CoV-2 es un βeta-coronavirus perteneciente a la familia Coronaviridae. Es un virus envuelto, cuyo material genético corresponde a ARN polaridad positiva, no segmentado y cuya envoltura le confiere gran susceptibilidad a los detergentes.

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Andersson, Klara, Ani Azatyan, Martin Ekenberg, et al. "A CRISPR-Cas13b System Degrades SARS-CoV and SARS-CoV-2 RNA In Vitro." Viruses 16, no. 10 (2024): 1539. http://dx.doi.org/10.3390/v16101539.

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In a time of climate change, population growth, and globalization, the risk of viral spread has significantly increased. The 21st century has already witnessed outbreaks of Severe Acute Respiratory Syndrome virus (SARS-CoV), Severe Acute Respiratory Syndrome virus 2 (SARS-CoV-2), Ebola virus and Influenza virus, among others. Viruses rapidly adapt and evade human immune systems, complicating the development of effective antiviral countermeasures. Consequently, the need for novel antivirals resilient to viral mutations is urgent. In this study, we developed a CRISPR-Cas13b system to target SARS

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Pattnaik, Bramhadev, Kuralayanapalya Puttahonnappa Suresh, Rajangam Sridevi, et al. "QUASISPECIES FEATURE IN SARS-CoV-2." Journal of Experimental Biology and Agricultural Sciences 9, no. 5 (2021): 591–97. http://dx.doi.org/10.18006/2021.9(5).591.597.

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Since the identification of the SARS-CoV-2, genus Beta- Coronavirus, in January 2020, the virus quickly spread in less than 3 months to all continents with a susceptible human population of about a 7.9billion, and still in active circulation. In the process, it has accumulated mutations leading to genetic diversity. Regular emergence of variants of concern/significance in different ecology shows genetic heterogeneity in the base population of SARS-CoV-2 that is continuously expanding with the passage of the virus in the vast susceptible human population. Natural selection of mutant occurs freq

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Khalid, Mohammad, Anas Alshishani, and Yousef Al-ebini. "Genome Similarities between Human-Derived and Mink-Derived SARS-CoV-2 Make Mink a Potential Reservoir of the Virus." Vaccines 10, no. 8 (2022): 1352. http://dx.doi.org/10.3390/vaccines10081352.

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SARS-CoV-2 has RNA as the genome, which makes the virus more prone to mutations. Occasionally, mutations help a virus to cross the species barrier. SARS-CoV-2 infections in humans and minks (Neovison vison) are examples of zoonotic spillover. Many studies on the mutational analysis of human-derived SARS-CoV-2 have been published, but insight into the mink-derived SARS-CoV-2 genome of mutations is still required. Here, we performed a mutation analysis of the mink-derived SARS-CoV-2 genome sequences. We analyzed all available full-length mink-derived SARS-CoV-2 genome sequences on GISAID (214 ge

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Arbel, Yuval, Chaim Fialkoff, Amichai Kerner, and Miryam Kerner. "Can Obesity Prevalence Explain COVID-19 Indicators (Cases, Mortality, and Recovery)? A Comparative Study in OECD Countries." Journal of Obesity 2022 (June 20, 2022): 1–10. http://dx.doi.org/10.1155/2022/4320120.

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SARS-CoV-2 virus disease (COVID-19) is declared a global pandemic with multiple risk factors. Obesity is considered by several researchers as one of the serious risk factors for SARS-CoV-2 virus complications based on recent empirical studies. Yet, other scholars argue in favor of the existence of an obesity survival paradox and criticize the former group of studies on the grounds that they lack controls for race, socioeconomic status, or quality of care. The objective of the current study is to analyze the potential relationships between different SARS-CoV-2 virus indicators and obesity on a

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Hocher, Berthold, Anne Schönbrunn, Xin Chen, Bernhard K. Krämer, and Volker von Baehr. "Outliers Matter—Correlation between S1 IgG SARS-CoV-2 Antibodies and Neutralizing SARS-CoV-2 Antibodies." Microorganisms 10, no. 10 (2022): 2067. http://dx.doi.org/10.3390/microorganisms10102067.

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Vaccination against the SARS-CoV-2 virus or infection with SARS-CoV-2 will lead to the development of IgG antibodies against the S1 protein of the SARS-CoV-2 virus. However, even despite having high levels of IgG antibodies against the S1 protein of the SARS-CoV-2 virus, (re-)infection may occur. We thus examined 2994 consecutive blood samples of outpatients from the Berlin-Brandenburg area in Germany in which IgG antibodies against the S1 protein of the SARS-CoV-2 virus as well as neutralizing SARS-CoV-2 virus antibodies were determined from the same sample. When analyzing the entire study po

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Urushidani, Masahiro, Akira Kawayoshi, Tomohiro Kotaki, Keiichi Saeki, Yasuko Mori, and Masanori Kameoka. "Inactivation of SARS-CoV-2 and influenza A virus by dry fogging hypochlorous acid solution and hydrogen peroxide solution." PLOS ONE 17, no. 4 (2022): e0261802. http://dx.doi.org/10.1371/journal.pone.0261802.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is transmitted mainly by droplet or aerosol infection; however, it may also be transmitted by contact infection. SARS-CoV-2 that adheres to environmental surfaces remains infectious for several days. We herein attempted to inactivate SARS-CoV-2 and influenza A virus adhering to an environmental surface by dry fogging hypochlorous acid solution and hydrogen peroxide solution. SARS-CoV-2 and influenza virus were air-dried on plastic plates and placed into a test chamber for i

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Lino, Alexandra, Marita A. Cardoso, Helena M. R. Gonçalves, and Paula Martins-Lopes. "SARS-CoV-2 Detection Methods." Chemosensors 10, no. 6 (2022): 221. http://dx.doi.org/10.3390/chemosensors10060221.

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A fast and highly specific detection of COVID-19 infections is essential in managing the virus dissemination networks. The most relevant technologies developed for SARS-CoV-2 detection, along with their advantages and limitations, will be presented and fully explored. Additionally, some of the newest and emerging COVID-19 diagnosis tools, such as biosensing platforms, will also be introduced. Considering the extreme relevance that all these technologies assume in pandemic control, it is of the utmost relevance to have an intrinsic knowledge of the parameters that need to be taken into consider

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Novilla, Arina, Iis Herawati, Lilis P. Friliansari, et al. "Sosialisasi Pencegahan Virus SARS-COV-2 Bagi Mahasiswa Prodi Teknologi Laboratorium Medis (D3) Stikes Jenderal Achmad Yani Cimahi." SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT 2021 1, no. 1 (2022): 859–65. http://dx.doi.org/10.33086/snpm.v1i1.889.

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Latar Belakang. Pemerintah selalu mengingatkan masyarakat untuk disiplin menerapkan protokol kesehatan, dikarenakan salah satu usaha untuk memutus mata rantai penyebaran virus SARS-COV-2 ini adalah menerapkan 3 M yaitu memakai masker, menjaga jarak dan mencuci tangan. Kegiatan sosialisasi pencegahan virus covid-19 melalui mahasiswa merupakan satu upaya untuk mencegah penyebaran virus tersebut. Metode. Kegiatan ini dilaksanakan 11 September 2020 secara daring. Mahasiswa diberikan kuisioner melalui Google Form untuk tracing penyebaran virus SARS-COV-2. Sebelum dilakukan sosialisasi, diberikan pr

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Havranek, Katherine Elizabeth, Ariana R. Jimenez, Marissa Danielle Acciani, et al. "SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus." Viruses 12, no. 12 (2020): 1465. http://dx.doi.org/10.3390/v12121465.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the most recent global pandemic that has caused more than a million deaths around the world. The spike glycoprotein (S) drives the entry and fusion of this virus and is the main determinant of cell tropism. To explore S requirements for entry under BSL2 conditions, S has been pseudotyped onto vesicular stomatitis virus (VSV) or retroviral particles with varied success. Several alterations to S were demonstrated to improve pseudoparticle titers, but they have not been systematically compared. In this study, w

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Nirjar, Bhattacharya. "Fundamentals of SARS CoV-2 Proteome and Variants." International Journal of Life Sciences 10, no. 4 (2022): 301–7. https://doi.org/10.5281/zenodo.7683858.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that is responsible for the COVID-19 pandemic. The currently ongoing COVID-19 pandemic has had devastating effects on human health, resulting in 219 million recorded cases and 4.55 million deaths worldwide. Beyond its direct impact on healthcare, this pandemic has also disrupted the daily lives of millions and will likely continue to do alter lifestyles for years through its negative impact on the economy. This paper aims to simplify the SARS-CoV-2 virus so that anybody can understand its molecular function. Th

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Bílek, R., V. Danzig, and T. Grimmichová. "Antiviral activity of amiodarone in SARS-CoV-2 disease." Physiological Research 71, no. 6 (2022): 869–75. http://dx.doi.org/10.33549/physiolres.934974.

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Amiodarone seems to exhibit some antiviral activity in the disease caused by SARS-CoV-2. Here we have examined the SARS-CoV-2 disease course in the entire population of the Czech Republic and compared it with the course of the disease in patients treated with amiodarone in two major Prague’s hospitals. In the whole population of the Czech Republic SARS-CoV-2 infected 1665070 persons (15.6 %) out of 10694000 (100 %) between 1 April 2020 and 30 June 2021. In the same time period only 35 patients (3.4 %) treated with amiodarone were infected with SARS-CoV-2 virus out of 1032 patients (100 %) who

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Cássio Santana Meira, Vinícius Pinto Costa Rocha, Iasmim Diniz Orge, et al. "Immunologic Responses against SARS-CoV-2." JOURNAL OF BIOENGINEERING AND TECHNOLOGY APPLIED TO HEALTH 3, no. 2 (2020): 165–76. http://dx.doi.org/10.34178/jbth.v3i2.123.

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Coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, in December 2019 and quickly spread worldwide becoming a global health problem unprecedented. The infection is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is characterized as a RNA virus with an envelope derived from host cell with glycoprotein spikes, appearing like a crown-like external structure under electron microscope. Due to the aggressive spread profile of SARS-CoV-2, the scientific community is under pressure to generate knowledge about the morphology of the virus and the immune response again

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Khutade, Kalpesh, Harshada Shah, Samiksha Patil, and Hiren Patel. "The Demographic and Clinical Characteristics of the Co-infection for the Detection of SARSCOV- 2 and Influenza A Virus by rRT-PCR." Journal of Advanced Scientific Research 15, no. 1 (2024): 9–13. http://dx.doi.org/10.55218/jasr.2024150102.

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The potential for co-infection with COVID-19 and other respiratory infections raises the possibility that a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mimics the influenza A virus regarding methods and modes of transmission, clinical features, related immune responses, and seasonal coincidence. This study aimed to investigate the presence of SARS-CoV-2 and influenza A virus coinfections inadmitted patients of a tertiary care hospital. In this study, the total included 589 admitted patients in our tertiary care hospital. The detectionof co-infection between SARS-CoV-2 and

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Micochova, Petra, Ambika Chadha, Timi Hesseloj, Franca Fraternali, Jeremy J. Ramsden, and Ravindra K. Gupta. "Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating." Wellcome Open Research 6 (March 11, 2021): 56. http://dx.doi.org/10.12688/wellcomeopenres.16577.1.

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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs via airborne droplets and surface contamination. Titanium dioxide (TiO2) coating of surfaces is a promising infection control measure, though to date has not been tested against SARS-CoV-2. Methods: Virus stability was evaluated on TiO2- and TiO2–Ag (Ti:Ag atomic ratio 1:0.04)-coated 45 x 45 mm ceramic tiles. After coating the tiles were stored for 2–4 months before use. We tested the stability of both SARS-CoV-2 Spike pseudotyped virions based on a lentiviral system, as well as fully infectious SARS-C

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Micochova, Petra, Ambika Chadha, Timi Hesseloj, Franca Fraternali, Jeremy J. Ramsden, and Ravindra K. Gupta. "Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating." Wellcome Open Research 6 (September 9, 2021): 56. http://dx.doi.org/10.12688/wellcomeopenres.16577.2.

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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs via airborne droplets and surface contamination. Titanium dioxide (TiO2) coating of surfaces is a promising infection control measure, though to date has not been tested against SARS-CoV-2. Methods: Virus stability was evaluated on TiO2- and TiO2–Ag (Ti:Ag atomic ratio 1:0.04)-coated 45 x 45 mm ceramic tiles. After coating the tiles were stored for 2–4 months before use. We tested the stability of both SARS-CoV-2 Spike pseudotyped virions based on a lentiviral system, as well as fully infectious SARS-C

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Todorović, Gordana, Aleksandar Joldžić, Slađana Anđelić, and Darko Nedeljković. "SARS-COV-2 transmission among family members." Halo 194 26, no. 3 (2020): 143–48. http://dx.doi.org/10.5937/halo26-28178.

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Introduction/Objective Severe acute respiratory distress syndrome caused by coronavirus 2 (SARS-COV-2) is a new respiratory disease -COVID-19. A virus from the Coronaviridae family, highly contagious and virulent took over the world in a very short time causing the 2019/2020 pandemic. We are presenting the case of COVID-19 transmission among family members, patients of various ages, sex, clinical presentation and findings, who have been infected in different ways. Case reports Three patients are described, all with different coronavirus-specific symptomatology. Symptoms ranged from fatigue and

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Alidjinou, Enagnon, Julien Poissy, Mahdi Ouafi, et al. "Spatial and Temporal Virus Load Dynamics of SARS-CoV-2: A Single-Center Cohort Study." Diagnostics 11, no. 3 (2021): 427. http://dx.doi.org/10.3390/diagnostics11030427.

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an ongoing pandemic. Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for the detection of SARS-CoV-2 and has been applied to different specimen types. Understanding the virus load and virus detection frequency in different specimen types is important to improve diagnosis and estimate the duration of potential infectivity. We conducted a retrospective single-center cohort study on hospitalized and outpatients with SARS-CoV-2 infection. We analyzed the frequency of virus detection, virus loa

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Fikriani, Choirun Nita, I. Kade Karisma Gita Ardana, and Dwi Listyorini. "The Comparison of SARS-CoV-2, SARS-CoV, and MERS-CoV Genome and Spike Protein Variations." Jurnal Riset Biologi dan Aplikasinya 3, no. 1 (2021): 38. http://dx.doi.org/10.26740/jrba.v3n1.p38-44.

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SARS-CoV-2 is a virus that has caused COVID-19 pandemic. This virus is a new variant of the SARS-CoV virus and also closely related to MERS-CoV, which caused similar acute respiratory infections. All these viruses recognize target cells by binding to the Receptor Binding Domain (RBD) on Spike protein with receptors. This study aimed to determine the SARS-CoV-2, MERS-CoV, and SARS-CoV genome structure, Spike protein sequence differences, and variations of RBD’s Receptor Binding Motif (RBM). This research was using data mining approach. Genome sequences were downloaded from NCBI, except for Indo

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Jahir, Pérez Sánchez, Sánchez Varela Alejandro, Cristina Rodríguez Luna Isabel, and Guillermo Estrada Franco José. "Rodent species as possible SARS-CoV-2 spills." GSC Biological and Pharmaceutical Sciences 22, no. 1 (2023): 295–301. https://doi.org/10.5281/zenodo.7661389.

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The current worldwide outbreak of COVID-19 is associated with a novel coronavirus, SARS-CoV-2. This outbreak has been tentatively associated with a seafood market in Wuhan, China, where the sale of wild animals may be the source of the zoonotic infection. When the epidemic, which began on December 12, 2019, had caused 2,794 laboratory-confirmed infections, including 80 deaths, as of January 26, 2020, whole-genome sequences were obtained from five patients early in the outbreak. The sequences were nearly identical and shared 79.6% sequence identity with SARS-CoV. In addition, SARS-CoV-2 has bee

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Purwandari, Vivi, Yosy Cinthya Eriwaty Silalahi, Artha Yuliana Sianipar, and Ledy Lenta Dirga Indah Mendrofa. "AKTIVITAS PENGHAMBATAN ENZIM PROTEASE 6LU7 VIRUS SARS-COV-2 OLEH SENYAWA DERIVAT KURKUMINOID SECARAIN SILICO." JURNAL FARMANESIA 8, no. 1 (2021): 1–8. http://dx.doi.org/10.51544/jf.v8i1.2779.

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Penggunaan curcumin sebagai penghambat enzim protease 6LU7 virus SARS-COV-2 sebagai bahan alam yang digunakan dalam terapi pendukung untuk menangani COVID-19 masih terdapat perdebatan dikarenakan curcumin dapat meningkatkan kadar protein ACE2 yang merupakan homolog ACE. Protease inhibitor disarankan menjadikan didatobat yang baik untuk menghentikan siklus hidup virus. Penelitian ini bertujuan untuk mengetahui aktivitas penghambatan enzim protease sars-cov-2 senyawa derivate kurkuminoid secara insilico, untuk mengetahui manfaat yang terdapat di dalam senyawa derivate kurkuminoid, dan untuk meng

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Zhou, Jie, Cun Li, Xiaojuan Liu, et al. "Infection of bat and human intestinal organoids by SARS-CoV-2." Nature Medicine 26, no. 7 (2020): 1077–83. https://doi.org/10.5281/zenodo.13535078.

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(Uploaded by Plazi for the Bat Literature Project) A novel coronavirus—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—emerged in humans in Wuhan, China, in December 2019 and has since disseminated globally1,2. As of April 16, 2020, the confirmed case count of coronavirus disease 2019 (COVID-19) had surpassed 2 million. Based on full-genome sequence analysis, SARS-CoV-2 shows high homology to SARS-related coronaviruses identified in horseshoe bats1,2. Here we show the establishment and characterization of expandable intestinal organoids derived from horseshoe bats of the Rhinoloph

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Zhou, Jie, Cun Li, Xiaojuan Liu, et al. "Infection of bat and human intestinal organoids by SARS-CoV-2." Nature Medicine 26, no. 7 (2020): 1077–83. https://doi.org/10.5281/zenodo.13535078.

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(Uploaded by Plazi for the Bat Literature Project) A novel coronavirus—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—emerged in humans in Wuhan, China, in December 2019 and has since disseminated globally1,2. As of April 16, 2020, the confirmed case count of coronavirus disease 2019 (COVID-19) had surpassed 2 million. Based on full-genome sequence analysis, SARS-CoV-2 shows high homology to SARS-related coronaviruses identified in horseshoe bats1,2. Here we show the establishment and characterization of expandable intestinal organoids derived from horseshoe bats of the Rhinoloph

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Andrasili, Johann, and Anak Agung Bagus Ngurah Nuartha. "SINDROM GUILLAIN-BARRE PADA PASIEN DENGAN INFEKSI SARS-COV-2 SELAMA MASA PANDEMI." Callosum Neurology 3, no. 3 (2020): 132–43. http://dx.doi.org/10.29342/cnj.v3i3.124.

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Latar Belakang: Corona Virus Disease 19 adalah penyakit yang disebabkan oleh virus korona yang sekarang dinamakan Severe Acute Respiratory Syndrome – Corona Virus -2 (SARS-CoV-2). Selain sistem pernapasan, penyakit ini utamanya dapat memengaruhi sistem saraf dalam bentuk penyakit autoimun salah satunya sindrom Guillain-Barre (SGB). Ditemukan sebanyak 12 laporan kasus dari berbagai negara yang menunjukkan pasien terinfeksi SARS-CoV-2 dengan SGB. Tujuan: Untuk menjelaskan patogenesis terjadinya SGB pada infeksi SARS-CoV-2 dan meningkatkan kewaspadaan klinisi terhadap kejadian ini. Diskusi: Keter

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Prasetyo, Dwi. "PENGGUNAAN EXTREME PROGRAMMING (EP) DALAM PENGEMBANGAN SISTEM INFORMASI GEOGRAFIS PENYEBARAN VIRUS CORONA SARS-COV-2." Jurnal Digit 14, no. 1 (2024): 09. http://dx.doi.org/10.51920/jd.v14i1.366.

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Virus CORONA SARS-COV-2 adalah penyakit yang baru muncul 2 tahun lalu, yang menyebabkan pilek ringan hingga berat, gangguan sistem pernapasan, dan penyakit serius seperti infeksi paru-paru yang mengakibatkan pergerakan ekonomi dan sistem pendidikan menurun. Sistem Informasi Geografis (SIG) dapat menyajikan informasi pemetaan Virus CORONA SARS-COV-2 dalam bentuk grafik dengan menggunakan peta sebagai interface. Melalui desain dan pengembangan, sistem GIS ini dapat menampilkan visualisasi dan informasi geografis tingkat penyebaran Virus CORONA SARS-COV-2 untuk mendapatkan informasi yang diperluk

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Auda, Ibtesam Ghadban, Jamela Auda, and Rajaa Hendi Salih. "SARS-CoV-2 and other Coronaviruses: A matter of variations." AL-Kindy College Medical Journal 19, no. 1 (2023): 5–10. http://dx.doi.org/10.47723/kcmj.v19i1.927.

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Since the appearance of COVID-19 disease as an epidemic and pandemic disease, many studies are performed to uncover the genetic nature of the newly discovered coronavirus with unique clinical features. The last three human coronavirus outbreaks, SARS-CoV, MERS-CoV and SARS-CoV-2 are caused by Beta-Coronaviruses. Horizontal genetic materials transfer was proven from one coronavirus to the other coronavirus of non-human origin like infectious bronchitis virus (IBV) of avian. Horizontal genetic materials transfer was also from non-corona viruses like astroviruses and equine rhinovirus (ERV-2) or

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Afewerky, Henok Kessete. "Pathology and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)." Experimental Biology and Medicine 245, no. 15 (2020): 1299–307. http://dx.doi.org/10.1177/1535370220942126.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta coronavirus that causes infectious respiratory disease, named as coronavirus disease of 2019 (COVID-19). While extensive studies have provided basic information on clinical characteristics of COVID-19, the disease pathology is not fully known. The SARS-CoV-2 virus structural studies and biochemical experiments have also indicated that the virus receptor-binding domain (RBD) binds with a high affinity to angiotensin-converting enzyme-2 (ACE-2) receptor from humans; however, the mechanism remains unclear. Hereunder, a summary

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Zandi, Milad, Saber Soltani, Mona Fani, Samaneh Abbasi, Saeedeh Ebrahimi, and Ali Ramezani. "Severe acute respiratory syndrome coronavirus 2 and respiratory syncytial virus coinfection in children." Osong Public Health and Research Perspectives 12, no. 5 (2021): 286–92. http://dx.doi.org/10.24171/j.phrp.2021.0140.

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Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has infected many people around the world. Children are considered an important target group for SARS-CoV-2, as well as other viral infections such as respiratory syncytial virus infection. Both SARS-CoV-2 and respiratory syncytial virus can affect the respiratory tract. Coinfection of SARS-CoV-2 and respiratory syncytial virus can pose significant challenges in terms of diagnosis and treatment in children. This review compares the symptoms, diagnostic methods, and treatment of

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Valsamatzi-Panagiotou, A., M. Traykovska, G. Y. Miloshev, and R. Penchovsky. "Various therapies against SARS-CoV-2." Acta Microbiologica Bulgarica 39, no. 1 (2023): 3–11. http://dx.doi.org/10.59393/amb23390101.

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An outbreak of coronavirus SARS-CoV-2 infection in December 2019 in Wuhan, a province of Chi¬na, has caused a worldwide pandemic that led to devastating effects on healthcare systems and the econ¬omy worldwide. The contagiousness of the infection and the consequences of the disease in everyday life highlighted the great need for a suitable treatment against coronavirus as soon as possible. Therefore, lots of scientists all around the world focused on the discovery of a proper therapy against the virus. The pres¬ent article explains the structure of the virus, the pathophysiology of the infecti

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Venuti, Aldo, Sara Donzelli, Paola Nisticò, Giovanni Blandino, and Gennaro Ciliberto. "Does Interleukin-6 Bridge SARS-CoV-2 With Virus-Associated Cancers?" Journal of Immunotherapy and Precision Oncology 4, no. 2 (2021): 79–85. http://dx.doi.org/10.36401/jipo-20-27.

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ABSTRACT To date SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), a member of the Coronaviridae family, has infected more than 40 million people worldwide. A second wave of SARS-CoV-2 infection is aggressively surging. The clinical worsening of SARS-CoV-2 infection appears to be strictly associated with comorbidities, which can be used to establish an intrinsic patient network whose molecular profile is pivotal for identifying and successfully treating populations at risk. Herein, we focus on the direct interaction between SARS-CoV-2 and virus-associated cancers, exploring the cri

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Kilroy, David, and Arun H. S. Kumar. "Anatomical perspective on the loss of smell and taste sensation in SARS-CoV-2 infection." Anatomy 14, no. 2 (2020): 145–49. http://dx.doi.org/10.2399/ana.20.049.

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The SARS-CoV-2 virus pandemic that originated from the Wuhan region of China continues to cause major disruptions globally. Loss of smell and taste sensation is reported to be an early indicators of SARS-CoV-2 infection. We provide here an anatomical perspective highlighting the anatomical regions, epithelial cell types and receptors categories involved in facilitating SARS-CoV-2 virus entry into host organism to rationalize the early loss of smell and taste sensation observed in patients infected with SARS-CoV-2 virus. We believe the anatomical perspective on anatomical regions, epithelial ce

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Vučanović, Tijana. "The impact of SARS - CoV-2 virus on consumer preferences." Poslovna ekonomija 15, no. 1 (2021): 32–45. http://dx.doi.org/10.5937/poseko19-32869.

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The SARS-CoV-2 virus appeared in the Chinese city of Wuhan, drastically changing consumer preferences ever since. Globalization and facilitated means of sharing information have had a considerable impact on consumer preferences. These preferences are ranked differently as a result of the unknown future of unfolding crisis. Specific changes in the business environment have caused intensive employment of crisis management and other comparable approaches in the problem-solving process in companies, which ensued as a result of the pandemic. The main purpose of this paper is to explain how consumer

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