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Dissertations / Theses on the topic 'Viruses'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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1

Afsharifar, Alireza. "Characterisation of minor RNAs associated with plants infected with cucumber mosaic virus." Title page, table of contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09pha2584.pdf.

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Bibliography: leaves 127-138. This thesis studies the minor double stranded RNAs (dsRNA) and single stranded RNAs (ssRNA) which are consistently associated with plants infected with Q strain of cucumber mosaic virus (Q-CMV). The investigations are focused on the structural elucidation of new RNAs which have been observed in single stranded and double stranded RNA profiles of Q strain of CMV.
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2

Chare, Elizabeth R. "Recombination in RNA viruses and plant virus evolution." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433381.

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3

Najmabadi, Hossein. "Characterization of the Self-Replicating Kirsten Murine Leukemia Viral DNA: Replication and Tetracycline Resistance." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc798479/.

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This research project deals with the characterization of self-replicating Kirsten murine viral DNA. The replication of this viral DNA and tetracycline resistance conferred to bacteria by this viral DNA will be studied. The restriction endonuclease and Southern blot analysis revealed a fragment of pBR322 from the Hind III and Pst I site that is located in the 3' end of the MLV-K:E molecule. Single stranded sequencing of the two terminal ends of this fragment verified that the 3' end of MLV-K:E contains identical sequence homology to pBR322. The presence of this pBR322 fragment explains the unus
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4

Yip, Chi-wai, and 葉志偉. "Characterization of the cell entry mechanism of infectious bursal disease virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44756306.

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5

Ong, Jamie. "In bed with viruses: The partnership between orchids, fungi and viruses." Thesis, Ong, Jamie (2016) In bed with viruses: The partnership between orchids, fungi and viruses. PhD thesis, Murdoch University, 2016. https://researchrepository.murdoch.edu.au/id/eprint/37275/.

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The Orchidaceae is the largest and most diverse angiosperm family comprising of five subfamilies, over 800 genera and over 26,000 species. In Western Australia, there are over 450 indigenous orchid species across 40 genera, concentrated predominately within the South West Australian Floristic Region, but with a few species in the tropical Kimberley. The southern species are all terrestrial and most belong to the Diurideae tribe, which are primarily restricted to Australia and New Zealand. To varying degrees, orchids rely on associations with other organisms, particularly fungi for nutrient pro
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6

Griffin, Jennifer Shoener. "Torque Teno Virus: A Potential Indicator of Enteric Viruses." Worcester, Mass. : Worcester Polytechnic Institute, 2009. http://www.wpi.edu/Pubs/ETD/Available/etd-031509-151117/.

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Thesis (M.S.)--Worcester Polytechnic Institute.<br>Keywords: cell culture; PCR; coliphage; coliform; fecal indicator; enteric virus; waterborne disease outbreak; TTV; torque teno virus. Includes bibliographical references (leaves 96-117).
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7

Chan, Yuk-on. "Impact of respiratory viruses on mortality." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/b39724025.

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8

Del, Valle Mendoza Juana, Tapia Ángela Cornejo, Pablo Weilg, et al. "Incidence of Respiratory Viruses in Peruvian Children With Acute Respiratory Infections." John Wiley & Sons, 2015. http://hdl.handle.net/10757/347016.

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jdelvall@upc.edu.pe<br>Acute respiratory infections are responsible for high morbi–mortality in Peruvian children. However, the etiological agents are poorly identified. This study, conducted during the pandemic outbreak of H1N1 influenza in 2009, aims to determine the main etiological agents responsible for acute respiratory infections in children from Lima, Peru. Nasopharyngeal swabs collected from 717 children with acute respiratory infections between January 2009 and December 2010 were analyzed by multiplex RT-PCR for 13 respiratory viruses: influenza A, B, and C virus; parainfluenza virus
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9

Zeicher, Marc. "Oncolytic viruses cancer therapy." Doctoral thesis, Universite Libre de Bruxelles, 2008. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210439.

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Wild-type viruses with intrinsic oncolytic capacity in human includes DNA viruses like some autonomous parvoviruses and many RNA viruses. Recent advances in molecular biology have allowed the design of several genetically modified viruses, such as adenovirus and herpes simplex virus that specifically replicate in, and kill tumor cells. However, still several hurdles regarding clinical limitations and safety issues should be overcome before this mode of therapy can become of clinical relevance. It includes limited virus spread in tumor masses, stability of virus in the blood, trapping within th
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10

Bieker, Jill M. "Chemical inactivation of viruses." Diss., Manhattan, Kan. : Kansas State University, 2006. http://hdl.handle.net/2097/226.

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11

Liu, X. Q. (Xingquan). "Differentiation of garlic viruses." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63286.

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12

Thomas, Joanne Marie. "Assembly of influenza viruses." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326757.

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13

Hale, Benjamin G. "Influenza A viruses and PI3K signalling /." St Andrews, 2008. http://hdl.handle.net/10023/483.

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14

Pulford, David J. "Expression of porcine transmissible gastroenteritis virus genes with recombinant viruses." Thesis, University of Reading, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305024.

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15

Ngamyeesoon, Nualphan. "Studies of viruses and virus-like agents infecting woody ornamentals." Thesis, University of Bath, 1989. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329558.

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16

Keese, Paul Konrad. "Structures of viroids and virusoids and their functional significance." Title page, contents and summary only, 1986. http://web4.library.adelaide.edu.au/theses/09PH/09phk268.pdf.

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17

Davis, Adam James. "Transcriptional analysis of human immunodeficiency virus type 1 infection following cell-to-cell transmission /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phd2609.pdf.

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18

Chan, Yuk-on, and 陳旭安. "Impact of respiratory viruses on mortality." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B39724025.

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19

Yama, Ninon Ines. "Viruses in rodents : from field work to virus discovery and characterization." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM5037.

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Les maladies émergentes représentent actuellement 65% de toutes les pathologies infectieuses récentes. Récemment, un nombre croissant de nouveaux virus a été associé à de petits mammifères terrestres, plus particulièrement à des rongeurs, désignant ce groupe comme étant l'une des possibles sources de dangereuses pathologies émergentes et ré-émergentes. Actuellement, la réaction en chaîne par polymérase (PCR) est l'outil principal utilisé pour la détection d'agents pathogènes dans la diagnostique de routine et dans la recherche. Or, plusieurs recherches ont montré que certaines substances inhib
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20

Nagano, Hideaki. "Studies on Plant-Virus Cell-to-Cell Movement Using Chimeric Viruses." Kyoto University, 2000. http://hdl.handle.net/2433/78105.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第8438号<br>農博第1122号<br>新制||農||801(附属図書館)<br>学位論文||H12||N3395(農学部図書室)<br>UT51-2000-F342<br>京都大学大学院農学研究科農林生物学専攻<br>(主査)教授 古澤 巌, 教授 泉井 桂, 教授 津田 盛也<br>学位規則第4条第1項該当
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21

Short, James Roswell. "An investigation into the replication biology of Helicoverpa armigera stunt virus." Thesis, Rhodes University, 2011. http://hdl.handle.net/10962/d1004026.

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Tetraviruses are a family of small non-enveloped positive sense RNA viruses that exclusively infect members of the order Lepidoptera. Their replication biology is poorly studied because, with the exception of Providence virus (PrV), tetraviruses are unable to replicate in tissue culture cells. The overall aim of the research described in this thesis was to develop a fundamental understanding of the replication of tetraviruses, focussing on the site of replication within host cells and in particular, the subcellular localisation of the viral replicase. Helicoverpa armigera stunt virus (HaSV, Ge
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22

Wang, Yuan Min. "In vivo and in vitro dynamics of HIV-1 in patients with and without antiretroviral treatment." Thesis, The University of Sydney, 2002. https://hdl.handle.net/2123/27848.

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Highly active antiretroviral therapy (HAART) successfully reduces plasma levels of HIV-1 RNA and improves the quality of life for HIV-infected patients. However, these clinical benefits may be limited by the emergence of multiple drug- and cross drug resistance in HIV-1, and also by the concealment of these viral variants in other sanctuary sites such as tissues, brain, lung and other blood cell types. Furthermore, the persistence of HIV reservoirs, including latently infected resting CD4 cells, brain, lymph tissue, bone marrow and genital tract, have posed a challenge to the long—term contro
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23

Plevka, Pavel. "Structure of Small Icosahedral Viruses." Doctoral thesis, Uppsala universitet, Strukturell molekylärbiologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-99933.

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This thesis presents structural studies on the plant virus Ryegrass mottle virus (RGMoV), the bacteriophage φCb5, and the icosahedral particles and octahedral crystal assembly of a bacteriophage MS2 coat protein mutant. In contrast to other sobemoviruses, the RGMoV coat protein is missing several residues in two of the loop regions important for capsid assembly. The first loop contributes to contacts between subunits around the quasi-three fold symmetry axis. The altered contact interface results in tilting of the subunits towards the quasi-threefold axis. The assembly of the T=3 capsid of sob
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24

Dunlop, K. A. "Respiratory viruses and meningococcal disease." Thesis, Queen's University Belfast, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446133.

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25

Rahnama, Leila. "Phylodynamics of Influenza A Viruses." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/31904.

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Human populations are constantly exposed to emerging pathogens such as influenza A viruses that result from cross-species transmissions. Generally these sporadic events are evolutionary dead-ends, but occasionally, viruses establish themselves in a new host that offers a novel genomic context to which the virus must adjust to avoid attenuation. However, the dynamics of this process are unknown. Here we present a novel method to characterize the time it takes to G+C composition at third codon positions (GC3 content) of influenza viruses to adjust to that of a new host. We compare the inferred d
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26

Stubbs, M. T. "Structural investigations of certain viruses." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376951.

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27

Etherington, Graham John. "Computational analysis of foodborne viruses." Thesis, University of East Anglia, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423473.

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28

Luke, James Steven. "Detecting previously unseen computer viruses." Thesis, University of Southampton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274015.

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29

Sun, Yunming. "Ribonucleotide reductase of herpes viruses." Thesis, Glasgow Caledonian University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364779.

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30

Gage, Zoe O. "Interferon, viruses and drug discovery." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/10127.

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The interferon (IFN) response is a crucial component of cellular innate immunity, vital for controlling virus infections. Dysregulation of the IFN response however can lead to serious medical conditions including autoimmune disorders. Modulators of IFN induction and signalling could be used to treat these diseases and as tools to further understand the IFN response and viral infections. We have developed cell-based assays to identify modulators of IFN induction and signalling, based on A549 cell lines where a GFP gene is under the control of the IFN-β promoter (A549/pr(IFN-β).GFP) and the ISRE
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31

Romijn, Phyllis Catharina. "Studies on porcine influenza viruses." Thesis, University of Surrey, 1989. http://epubs.surrey.ac.uk/847965/.

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A number of different cell cultures were examined for their susceptibility to the influenza virus A/swine/Weybridge/86(H1N1) and A/swine/Weybridge/87(H3N2). PK1 (porcine kidney) was found to be the most susceptible to the viruses, and MDCK (canine kidney), the best cell line for primary isolation. A method of infectivity assay by immunoperoxidase in microplate cultures of MDCK cells was developed which was simple enough for routine use and practically as sensitive as the egg infectivity test. The potential risks of accidental importation of influenza infection in pig was assessed by determinin
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32

Pereira, Pagarete Antonio Joaquim. "Functional Genomics of Coccolithophore Viruses." Paris 6, 2010. http://hal.upmc.fr/tel-01111009v1.

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L’Emiliania huxleyi virus (EhV) est un NCLDV. Il appartient à la famille des virus algaux, les Phycodnaviridae. Il infect Emiliania huxleyi, le coccolithophore le plus abondant dans les océans modernes. Nous avons montré sur une base phylogénétique le transfert de 29 gènes entre le génome d’Emiliania huxleyi et de EhV, notamment 7 gènes impliqués dans la biosynthèse des sphingolipides (SBP). C’est le premier cas patent, dans un système de virus et phytoplancton eucaryotes, de transfert horizontal de multiples gènes d’enzymes liées fonctionnellement. Pour deux des plus importantes enzymes de la
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33

Costa, Liliana Andreia dos Santos. "Photoinactivation of viruses by porphyrins." Doctoral thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/10869.

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Doutoramento em Biologia<br>A inativação fotodinâmica tem sido usada com sucesso na inativação de microorganismos. Diversos aspetos da inativação fotodinâmica foram já estudados para diferentes microrganismos, contudo, existe ainda pouca informação disponível no que diz respeito à inativação de bacteriófagos por processos fotodinâmicos. Este trabalho pretendeu elucidar e avaliar vários aspetos da fotoinativação de vírus, em particular de bacteriófagos, incluindo (i) o efeito de diversos parâmetros de luz utilizados na fotoinativação de bacteriófagos; (ii) a eficiência da inativação foto
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34

Olabode, Abayomi. "The evolution of RNA viruses." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/the-evolution-of-rna-viruses(ac87e71c-e9ce-44c6-8dc1-6adbb01e5efb).html.

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This thesis analyzes the evolutionary trajectories that drive the evolution of several RNA viruses. These viruses have been identified to be the leading causes of viral outbreaks and deaths in humans. Studying the mechanisms influencing their evolution could therefore produce vital information for controlling the spread of these viruses or for their eradication. The availability of huge sequence repositories and advancement in computing and sequencing technologies allows for the development of novel methods for understanding the evolution of viruses even during an on-going outbreak, epidemic o
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35

Choudhury, Md Abu Hasnat Zamil. "Population Dynamics of RNA viruses." Thesis, Queensland University of Technology, 2013. https://eprints.qut.edu.au/60866/1/Md._Choudhury_Thesis.pdf.

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Between 50 and 100 million people are infected with dengue viruses each year and more than 100,000 of these die. Dr Choudhury has demonstrated that populations of dengue viruses in individual patients are genetically and functionally very diverse and that this diversity changes significantly at the time of major outbreaks of disease. The results of his studies may inform strategies which will make dengue vaccines far more effective.
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36

Besozzi, M. "RESPIRATORY VIRUSES IN ALPINE CHAMOIS." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/351709.

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In the heterogeneous ecosystem of the Alps an interdisciplinary approach is necessary to prevent, survey and control wildlife diseases in order to ensure the biological integrity, the environmental conservation and so the biodiversity. In this contest the matter of livestock-wildlife interface is of particular importance for the presence of grazing domestic herds and the increase of wild ruminants populations, that lead to novel cohabitation situations with a possible “spill-over” of diseases from livestock or vice versa. Livestock-wildlife interfaces are dynamic and bidirectional and pathogen
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37

Szeto, Wai-chi. "Computer virus prevention and control in Hong Kong /." [Hong Kong] : University of Hong Kong, 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13302371.

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38

Boz, Mustafa Burak. "Modeling and simulations of single stranded rna viruses." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/44815.

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The presented work is the application of recent methodologies on modeling and simulation of single stranded RNA viruses. We first present the methods of modeling RNA molecules using the coarse-grained modeling package, YUP. Coarse-grained models simplify complex structures such as viruses and let us study general behavior of the complex biological systems that otherwise cannot be studied with all-atom details. Second, we modeled the first all-atom T=3, icosahedral, single stranded RNA virus, Pariacoto virus (PaV). The x-ray structure of PaV shows only 35% of the total RNA genome and 8
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39

Goffin, Véronique. "Etude de la région cis-régulatrice positive associée à un site hypersensible aux nucléases et localisée dans le gène pol du virus HIV-1 (Human Immunodeficiency virus type 1)." Doctoral thesis, Universite Libre de Bruxelles, 2005. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210907.

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40

Tomasicchio, Michele. "Assembly of Omegatetravirus virus-like particles in the yeast Saccharomyces cerevisiae." Thesis, Rhodes University, 2008. http://hdl.handle.net/10962/d1003989.

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The Tetraviridae are a family of ss (+) RNA viruses that specifically infect lepidopteran insects. Their icosahedral capsids are non-enveloped and approximately 40 nm in diameter with T=4 quasi-equivalent symmetry. The omegatetraviruses, which are structurally the best characterised in the family, include Helicoverpa armigera stunt virus (HaSV) and Nudaurelia capensis omega virus (NwV). The omegatetravirus procapsid is composed of 240 identical copies of the capsid precursor proteins, which undergo autoproteolytic cleavage at its carboxyl-terminus generating the mature capsid protein (b) and γ
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41

Wang, Andrew C. "Recombination of Two RNA Viruses: Red Clover Necrotic Mosaic Virus and Carnation Ringspot Virus." Thesis, The University of Arizona, 2010. http://hdl.handle.net/10150/146250.

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In this research project, two plant RNA viruses, Red clover necrotic mosaic virus (RCNMV) and Carnation Ringspot Virus (CRSV) were studied and two recombinants were created using RNA1 of RCNMV and RNA2 of CRSV (R1+C2) for one recombinant and RNA2 of RCNMV and RNA1 of CRSV (C1+R2) for the other recombinant. Nicotiana clevelandii and Nicotiana benthamiana were inoculated with the wild types and the two recombinants. The tissues of the plants were extracted for total RNA and a reverse transcription polymerase chain reaction was performed on the total RNA. Using specific primers, the RCNMV wild ty
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42

Goka, Edward Anthony Chilongo. "Influenza A viruses dual and multiple infections with other respiratory viruses and risk of hospitalization and mortality." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/influenza-a-viruses-dual-and-multiple-infections-with-other-respiratory-viruses-and-risk-of-hospitalization-and-mortality(256eb122-a52a-4276-8dc1-28b5a2cc6662).html.

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Introduction: Epidemiological studies have indicated that 5-38% of influenza like illnesses (ILI) develop into severe disease due to, among others, factors such as; underlying chronic diseases, age, pregnancy, and viral mutations. There are suggestions that dual or multiple virus infections may affect disease severity. This study investigated the association between co-infection between influenza A viruses and other respiratory viruses and disease severity. Methodology: Datum for samples from North West England tested between January 2007 and June 2012 was analysed for patterns of co-infection
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43

Li, Tin-wai Olive. "Influenza polymerase subunit compatibility between human H1 and H5 viruses." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B41896890.

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44

Exline, Colin Michael Stoltzfus C. Martin. "The positive regulation of HIV-1 Vif mRNA splicing is required for efficient virus replication." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/356.

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45

Rosskopf, John J. "CIS-acting signals for replication of Nodamura virus RNA1." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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46

Leung, Lok Chun Rogen. "Novel fluorescence and fluorine labelling methods for viruses and virus-like particles." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:26f1f546-367a-4a6d-8d01-8b05ef24ac74.

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Molecular imaging involves the development of probes which can specifically label a certain object in the body at cellular or subcellular level. This thesis consists of three parts, each involving the development of novel labelling methods for viruses or virus-like particles with specific applications. Virus-like particles (VLP) derived from the E. coli bacteriophage Q&beta; are widely employed as a nano-carrier for drugs and vaccines, but a powerful method for tracing its circulation without affecting its structure is yet to be developed. In the first part of the thesis, the electrophilic flu
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47

Perkins, Colin J. "A study of some viruses and virus-like agents infecting woody ornamentals." Thesis, University of Bath, 1987. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376333.

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48

Enriquez-Enriquez, Carlos. "Detection and survival of selected viruses in water." Diss., The University of Arizona, 1994. http://hdl.handle.net/10150/186948.

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Nucleic acid hybridization (gene probe) and polymerase chain reaction (PCR) techniques have been used to detect viral nucleic acid in water. However, gene probe and PCR may not distinguish between infectious and noninfectious viruses. This study evaluated the ability of gene probe to detect viable poliovirus 1 (polio 1), from sterile and nonsterile groundwater, and the ability of PCR to detect infectious human immunodeficiency virus (HIV-1) from tap and wastewater. The plaque forming (BGM cells), and the tissue culture infectious dose fifty (TCID₅₀) (PLC/PRF/5 cells) procedures were used to de
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49

De, Silva Naomi Samantha. "Targeting Tumour Vasculature with Oncolytic Viruses." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31735.

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Oncolytic viruses (OVs) have been engineered or selected for cancer cell-specific infection; however, we have found that following intravenous administration of vesicular stomatitis virus (VSV), tumour cell killing rapidly extends far beyond the initial sites of infection. This Bystander Effect is due to the virus’ ability to specifically target tumour vasculature through tumour-specific infection of tumour endothelium and the induction of an inflammatory response resulting in tumour-restricted coagulation, acute vascular disruption, apoptosis and necrosis of the tumour core. VSV-infected tumo
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50

Caddy, Sarah. "Characterisation of enteric viruses in dogs." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/39793.

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Human noroviruses (HuNoV) are a significant cause of viral gastroenteritis in man worldwide. Noroviruses are also associated with intestinal disease in multiple species, including dogs. Canine norovirus (CNV) was initially discovered in 2007 and the first aim of this thesis was to determine the prevalence of CNV in the UK dog population. qPCR screening of canine stool samples did not identify CNV RNA, but canine astroviruses (CaAstV) were serendipitously identified and subsequently characterized according to the second aim of this work. For serological screening, CNV virus-like particles (VLPs
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