Dissertations / Theses on the topic 'Visual guidance systems'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 32 dissertations / theses for your research on the topic 'Visual guidance systems.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Clark, Nicholas, Fiona Dunne, Michael Lee, and Hua Lee. "HIGH-PERFORMANCE FULL-VIEW VISION SYSTEM WITH GUIDANCE SUPPORT OF ACOUSTIC AND MICROWAVE ARRAYS." International Foundation for Telemetering, 2006. http://hdl.handle.net/10150/604107.
Full textThis paper describes the concept of wide-angle coverage optical vision system integrated with guidance support of microwave or acoustical imaging arrays. The objective is to provide the capability of effective high-resolution full-view monitoring and sensing. The optical component, formed by a multi-camera array, is responsible for the main interface with human users. The acoustical and microwave arrays are integrated, allowing the system to function in the event-triggered modality for optimal efficiency. In this paper, the arrays discussed are in circular configurations. With minor modification, the system can also function with linear array configurations.
Korvala, T. (Tapio), and H. (Hannu) Raappana. "Open visual guidance system for mobile senior citizen." Master's thesis, University of Oulu, 2015. http://urn.fi/URN:NBN:fi:oulu-201505211603.
Full textDeng, C. (Canrong). "Multi user support for senior citizen visual guidance system." Master's thesis, University of Oulu, 2016. http://urn.fi/URN:NBN:fi:oulu-201603251353.
Full textHolt, Ryan S. "Three Enabling Technologies for Vision-Based, Forest-Fire Perimeter Surveillance Using Multiple Unmanned Aerial Systems." BYU ScholarsArchive, 2007. https://scholarsarchive.byu.edu/etd/931.
Full textVieira, Bruno Carvalho. "Retrofitting of the Robuter's platform to an AGV with visual guidance." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22379.
Full textThe industrial automation has made its way in responding to the growing market’s needs. Companies that wish to keep up with the competition have a common goal: improve the product’s quality while reducing manufacturing costs and time. In the last decade, the autonomous guided vehicles (AGV) have gained expression due to the fact that they are capable of responding this the last mentioned necessity. The context of the current dissertation is inserted in the development of this thematic through the recovery of an equipment with industrial scale applications. The main goal is centered in the Robuter II platform’s retrofitting. For that, it is intended to replace the old control part by a modern solution that allows the integration of different modules based on a ROS distributed architecture. A detailed analysis of the existing platform was made in order to redo all the electrical installation, as well as to setup all of the used equipment. In the end, a vehicle capable of navigating, both manual and autonomously, was achieved. The vehicle can be operated manually (via remote control) and as a proof of concept, autonomous navigation was carried out through a simple artificial vision algorithm. It was also verified the versatility of the developed solution by integrating different equipment and designed code in a simple way. This document describes generally the project where all the different steps are identified, as well as all the work developed until the present moment. Furthermore, the guidelines to follow in order to achieve the proposed goals, is presented. Finally, navigation experimental results and the integration of different works on the platform are presented.
A automação industrial é uma parte fundamental para responder às crescentes necessidades do mercado. As empresas que desejam estar a par da competição, têm todas uma premissa em comum — melhorar a qualidade do produto, reduzindo custos e tempo de fabrico. Na última década, os veículos autonomamente guiados (AGV) têm ganho expressão devido ao facto de serem capazes de responder a esta última necessidade. O contexto da presente dissertação insere-se no desenvolvimento desta temática através da recuperação de um equipamento com aplicações à escala industrial. O objetivo principal passa por fazer o retrofitting da plataforma Robuter II, que se encontra obsoleta. Para isso, pretende-se substituir toda a parte de controlo por uma solução mais atual que permita a integração de diferentes módulos com base numa arquitetura distribuída baseada em ROS. Foi então necessário proceder a uma análise detalhada da plataforma existente para refazer toda a instalação elétrica da mesma, bem como proceder à instalação de diversos equipamentos. No final, obteve-se um veículo capaz de navegar de forma manual (com controlo remoto) e foi ainda realizada uma prova de conceito de navegação autónoma através da realização de um algoritmo simples de visão artificial. Foi ainda verificada a versatilidade suficiente para integrar diferentes equipamentos e código desenvolvido de forma simples. Neste documento é feita uma descrição geral do projeto onde são identificadas as várias etapas do mesmo e o trabalho desenvolvido até ao momento. Para além disso, é apresentada a forma como se irá proceder para a implementação das metas propostas. Por último, são apresentados resultados experimentais de navegação e integração de outros trabalhos na plataforma.
Hunaiti, Ziad Ali. "A remote vision guidance system for visually impaired pedestrians." Thesis, Brunel University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427665.
Full textTaylor, Brandon Lee. "Smart Phone-based Indoor Guidance System for the Visually Impaired." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/3092.
Full textBazigou, Eleni. "Analysis of target-derived factors regulating axon guidance in the visual system of Drosophila." Thesis, Open University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429534.
Full textGaraj, Vanja. "Design of the system for remote sighted guidance of visually impaired pedestrians." Thesis, Brunel University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426222.
Full textPugliesi, Edmur Azevedo [UNESP]. "Avaliação da comunicação cartográfica de sistema de navegação e guia de rota em automóvel." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/100269.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O objetivo desta pesquisa é avaliar representações cartográficas para manutenção na rota, em um Mapa Visual Dinâmico de Sistema de Navegação e Guia de Rota em Automóvel (SNGRA), por meio das análises de demanda visual, preferência subjetiva e erro navegacional. Os pontos de referência e os sinais de direção de trânsito são elementos de informação importantes que auxiliam os motoristas nas tarefas de manutenção na rota. A tese central é que o Mapa Visual Dinâmico de um SNGRA pode apresentar baixa demanda visual, alta preferência subjetiva e pouco erro navegacional quando se combina representação cartográfica áudio-dinâmica com pontos de referência representados na perspectiva do motorista e representação de seta para indicar a direção da manobra. Os elementos de pontos de referência foram selecionados a partir das características da atratividade visual e cognitiva de um pequeno espaço urbano brasileiro e, principalmente, da rota de teste. As representações cartográficas foram produzidas com base em fatores humanos (cognição, percepção e atenção) e, testadas junto a um grupo de 28 motoristas. Utilizou-se a estatística não paramétrica para analisar os dados coletados nos testes de demanda visual. Os resultados indicam as representações cartográficas eficientes e eficazes para manutenção na rota, bem como apontam a relação da demanda visual com os fatores sexo, habilidade espacial e experiências com mapas. Este trabalho confirma os resultados de pesquisas anteriores de que os motoristas preferem mapas para navegação e guia de rota em automóvel porque querem conhecer sua localização e o contexto espacial, em relação às referências urbanas.
The aim of this research is to evaluate cartographic symbols for route following in a Dynamic Visual Map of a Car Navigation and Route Guidance System, taking into account visual demand, subjective preference and navigational error. Landmarks and traffic signs are information elements that help drivers when following a route. The central hypothesis is that Dynamic Visual Map could be more efficient and effective when combining audio-dynamic cartographic representation with landmarks in a driver's perspective view and arrow to indicate maneuver direction. The landmarks were selected from characteristics of visual and cognitive attractiveness from a town and, mainly of the test route. The cartographic symbols were produced based on human factors (cognition, perception and attention) and tested with 28 drivers. Non-parametric statistic was applied in order to analyze the collected data from visual demand test. The results indicate cartographic symbols efficient and effective for route following, as well as point out association between visual demand with sex, spatial abilities and experiences with maps factors. This work confirm previous research that the most of drivers prefer maps to navigation and route following in car, because they want know en-route where they are in relation to particular areas and landmarks.
McKinnell, Iain W. "Neurobiological analysis of axon guidance in the developing chick visual system : the role of receptor-like protein tyrosine phosphatases." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365362.
Full textGodement, Pierre. "Guidage axonal et formation de cartes topographiques dans le système visuel de la souris." Paris 6, 1990. http://www.theses.fr/1990PA066148.
Full textPugliesi, Edmur Azevedo. "Avaliação da comunicação cartográfica de sistema de navegação e guia de rota em automóvel /." Presidente Prudente : [s.n.], 2007. http://hdl.handle.net/11449/100269.
Full textBanca: Vilma Mayumi Tachibana
Banca: Nilton Nobuhiro Imai
Banca: Claudia Robbi Slutter
Banca: Luciene Stamato Delazari
Resumo: O objetivo desta pesquisa é avaliar representações cartográficas para manutenção na rota, em um Mapa Visual Dinâmico de Sistema de Navegação e Guia de Rota em Automóvel (SNGRA), por meio das análises de demanda visual, preferência subjetiva e erro navegacional. Os pontos de referência e os sinais de direção de trânsito são elementos de informação importantes que auxiliam os motoristas nas tarefas de manutenção na rota. A tese central é que o Mapa Visual Dinâmico de um SNGRA pode apresentar baixa demanda visual, alta preferência subjetiva e pouco erro navegacional quando se combina representação cartográfica áudio-dinâmica com pontos de referência representados na perspectiva do motorista e representação de seta para indicar a direção da manobra. Os elementos de pontos de referência foram selecionados a partir das características da atratividade visual e cognitiva de um pequeno espaço urbano brasileiro e, principalmente, da rota de teste. As representações cartográficas foram produzidas com base em fatores humanos (cognição, percepção e atenção) e, testadas junto a um grupo de 28 motoristas. Utilizou-se a estatística não paramétrica para analisar os dados coletados nos testes de demanda visual. Os resultados indicam as representações cartográficas eficientes e eficazes para manutenção na rota, bem como apontam a relação da demanda visual com os fatores sexo, habilidade espacial e experiências com mapas. Este trabalho confirma os resultados de pesquisas anteriores de que os motoristas preferem mapas para navegação e guia de rota em automóvel porque querem conhecer sua localização e o contexto espacial, em relação às referências urbanas.
Abstract: The aim of this research is to evaluate cartographic symbols for route following in a Dynamic Visual Map of a Car Navigation and Route Guidance System, taking into account visual demand, subjective preference and navigational error. Landmarks and traffic signs are information elements that help drivers when following a route. The central hypothesis is that Dynamic Visual Map could be more efficient and effective when combining audio-dynamic cartographic representation with landmarks in a driver's perspective view and arrow to indicate maneuver direction. The landmarks were selected from characteristics of visual and cognitive attractiveness from a town and, mainly of the test route. The cartographic symbols were produced based on human factors (cognition, perception and attention) and tested with 28 drivers. Non-parametric statistic was applied in order to analyze the collected data from visual demand test. The results indicate cartographic symbols efficient and effective for route following, as well as point out association between visual demand with sex, spatial abilities and experiences with maps factors. This work confirm previous research that the most of drivers prefer maps to navigation and route following in car, because they want know en-route where they are in relation to particular areas and landmarks.
Doutor
Symonds, Andrew C. E. "Investigating the expression of the topographic guidance molecules, EphA5 and ephrin-A2, as well as metallothionein function, in the injured and regenerating adult mammalian visual system." University of Western Australia. School of Animal Biology, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0109.
Full textEl, Sayah Jihane. "Contribution à la modélisation, à la simulation et à l'évaluation d'applications nomades à intelligence répartie : application à l'assistance aux voyageurs aveugles dans les transports publics et les pôles d'échanges." Thesis, Paris Est, 2009. http://www.theses.fr/2009PEST1032/document.
Full textThe development of communication and locating systems and the progress of mobile devices have made possible new applications and services, allowing access to real-time information and improving the integration of blind people. ln this context, the thesis has contributed to the development of an information and guidance system to be used by blind travellers in public transports. The work has focused on two critical aspects for this kind of systems: the reliability of data transmission and the ability of localizing and guiding the user in an efficient way. A simulation environment has also been developed that can be used for the prototyping and the analysis of the mobile application as well as for the study of communication over the wireless network. The thesis is based on the results of the RAMPE and INFOMOVILLE projects
Tang, Zhiqi. "Commande référencée vision de drones aériens." Thesis, Université Côte d'Azur, 2021. http://www.theses.fr/2021COAZ4018.
Full textThis thesis proposes novel vision-based controllers for the guidance of Unmanned Aerial Vehicles (UAVs). It considers scenarios involving both single and multiple vehicles. For the case of a single-vehicle, novel Image-based visual servo control (IBVS) approaches are proposed for both fixed-wing and vertical take-off and landing (VTOL) UAVs operating in urban or congested environments. Navigation tasks in a complex environment with obstacle avoidance capabilities are considered. In particular, the landing of fixed-wing UAVs on an airstrip and the landing of VTOL-UAVs that includes an obstacle avoidance strategy are considered. The originality of the study lies in the direct exploitation of the centroid of the image of the observed pattern together with the optical flow, thereby eliminating the need to estimate the position and the velocity of the UAV.For multiple vehicles, novel bearing formation controllers are designed for formations under both directed and undirected interaction topologies. Optical flow is explored in the bearing formation control laws in order to achieve collision avoidance between different agents during the formation progression.In order to relax the classical conditions required by bearing rigidity theory and to lift the scale ambiguity caused by bearings, persistence of excitation of the desired bearing reference is explored. The proposed methodology is supported by rigorous mathematical tools (This involves nonlinear dynamical systems and analysis using Lyapunov theory to formally prove the asymptotic (or exponential) stability of the system, guarantee robustness, and finally ensure good performance of the closed-loop system). Further support is provided by real experiments and/or simulation results
Montuwy, Angélique. "Efficacité et expérience utilisateur de guidages visuels, auditifs et haptiques pour les piétons âgés." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLT001.
Full textAs worldwide population is ageing and concentrating in cities, maintaining older people's pedestrian mobility in urban areas has become a key issue for their health and autonomy. Walking is, indeed, one of the most frequent transportation mode used by older people in cities. But age-related perceptual, cognitive and physical declines could negatively impact this daily activity.Pedestrian navigation, which consists in moving from a point A to a point B, could be particularly affected when advancing in age. It involves complex cognitive and perceptual processes to perceive and understand a multiplicity of information required to reach destination. Older people tend to use paper maps to help them finding their way while navigating. But maps are not suitable for older pedestrians because they provide allocentric information (viewed from the top) which is difficult to understand when advancing in age and requires a lot of visual attention which is also needed to navigate safely. Technological pedestrian navigation aids (such as GPS systems) may help older people to navigate by providing them guidance messages via various sensory modalities in order to limit attention sharing. Those aids should also be related to a positive user experience to facilitate their acceptation among older people who feel not necessarily comfortable with technologies. This thesis in ergonomic psychology focuses on how older people perceive and experience various technological pedestrian navigation aids, providing them with visual, auditory and haptic egocentric turn-by-turn guidance messages. We firstly investigated the reasons why people use pedestrian mobility in their daily activities and the differences existing between retired and non-retired people (study 1). We then compared some step-by-step guidance messages to a paper map in a virtual environment (study 2). We used visual messages (arrows inlayed on the screen of the simulator), auditory messages (spatialized sounds provided by a bone-conduction headset) and haptic messages (vibrating watch around the right wrist) and highlighted that the increased difficulties faced by older people to find their way with a map could be compensated using visual arrows or spatialized sound. We then continued this work in a real urban environment (study 3). People were asked to navigate some routes with their own navigation aid (usually a map), or arrows inlayed in their field of view thanks to augmented-reality glasses, or spatialized sounds provided by a bone-conduction headset, or arrows displayed on a smartwatch that vibrated to announce that a visual message was incoming. Augmented-reality glasses were less suitable for older pedestrians than bone-conduction headset and smartwatch in the natural environment, which was different from the results observed in virtual environment. Results from the interviews showed that the perceptibility of the messages, the way people interpreted them in the environment, and the comfort people felt was highly conditioned by the device used. We finally investigated which UX dimensions cloud foster or limit the acceptability of some sensory navigation aids that do not exist yet but could exist in a near future (augmented-reality lens, vibrating clothes etc.).As a conclusion, we provide the reader with recommendations for designing navigation aids that are adapted to older pedestrians’ needs and expectations
Larnaout, Dorra. "Localisation d'un véhicule à l'aide d'un SLAM visuel contraint." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2014. http://tel.archives-ouvertes.fr/tel-01038016.
Full textMhiri, Rawia. "Approches 2D/2D pour le SFM à partir d'un réseau de caméras asynchrones." Thesis, Rouen, INSA, 2015. http://www.theses.fr/2015ISAM0014/document.
Full textDriver assistance systems and autonomous vehicles have reached a certain maturity in recent years through the use of advanced technologies. A fundamental step for these systems is the motion and the structure estimation (Structure From Motion) that accomplish several tasks, including the detection of obstacles and road marking, localisation and mapping. To estimate their movements, such systems use relatively expensive sensors. In order to market such systems on a large scale, it is necessary to develop applications with low cost devices. In this context, vision systems is a good alternative. A new method based on 2D/2D approaches from an asynchronous multi-camera network is presented to obtain the motion and the 3D structure at the absolute scale, focusing on estimating the scale factors. The proposed method, called Triangle Method, is based on the use of three images forming a. triangle shape: two images from the same camera and an image from a neighboring camera. The algorithrn has three assumptions: the cameras share common fields of view (two by two), the path between two consecutive images from a single camera is approximated by a line segment, and the cameras are calibrated. The extrinsic calibration between two cameras combined with the assumption of rectilinear motion of the system allows to estimate the absolute scale factors. The proposed method is accurate and robust for straight trajectories and present satisfactory results for curve trajectories. To refine the initial estimation, some en-ors due to the inaccuracies of the scale estimation are improved by an optimization method: a local bundle adjustment applied only on the absolute scale factors and the 3D points. The presented approach is validated on sequences of real road scenes, and evaluated with respect to the ground truth obtained through a differential GPS. Finally, another fundamental application in the fields of driver assistance and automated driving is road and obstacles detection. A method is presented for an asynchronous system based on sparse disparity maps
Lin, Chung-Fu, and 林重甫. "Automatic Visual Guidance System of Intelligent Vehicle." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/50426584658474642950.
Full text國立交通大學
機械工程系
89
As the speed of computer becomes faster, the application of the machine vision is also broadened. In this work, we apply the machine vision to the automatically visual guidance of the intelligent vehicle. By the image process and the camera calibration, we can find the curvature of the road and provide this information to the vehicle dynamic system. Thus the vehicle can trace the road automatically. Since the data of the image is too large and image process takes much time. So it is hard to apply the machine vision to the high-speed control system. In order to shorten the time of image process, we use the control theorem, combine the road model and the vehicle model to predict the position of the feature object on the image. In this way, it makes possible to apply the machine vision to the high-speed control system.
Hwang, You-Xiang, and 黃祐翔. "A Study on the Visual Guidance Control System of Robots." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/67431966417208786163.
Full text大同大學
機械工程學系(所)
99
This paper presents a PC based vision system and control scheme for guiding the autonomous robot in unknown environment. By using Kinect from Microsoft newest product, the vision system measures the three dimensional relative distance and builds a map between the robot and surrounding object. The robot includes a MCU (Microchip PIC18F4520) as control unit and a Bluetooth as wireless communication module. According to the map, system can control and guide a wireless robot moving to command position and avoiding obstacles in Kinect's visible area. With this system, user can set a goal on the map, then the robot will be guided to move to the goal.
Lu, Wei-Chuan, and 陸偉權. "A Study on The Visual Guidance Control System of Intelligent Domestic Vacuum." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/53351542662875233974.
Full text大同大學
機械工程學系(所)
93
With the speed up of computer efficiency and bandwidth of network, the digital consumer products have been incorporated among our life gradually. A visual guidance system with wireless control was proposed in this thesis to control an intelligent domestic vacuum(IDV), which can developed the moving paths to clean a dusty area automatically. The histogram thresholding method and the manual decided threshold were used to isolate the image of IDV and T shape mark image (on the top of IDV)from the real time image. A shape center-calculating and shape-calculating algorithms were developed to calculate the position and the direction of intelligent domestic vacuum. There are two operation modes were developed in this study. When system operated under the manual guidance mode, user can set the moving path. On the other hand, the moving path was created automatically by the system in visual guidance mode. And the system will generate the guidance paths with proposed algorithm. Finally, the system drives the IDV automatically and compares its real position with the generated guidance paths until the mission finished.
Lee, Chih-Wei, and 李至偉. "Wearable Guidance System Based on Voice-Marker Recognition for People with Visual Impairment." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/59914176971253826949.
Full text國立臺灣科技大學
電子工程系
105
There are 285 million people with visually impairment in the world, helping them walking free on a familiar/unfamiliar place is an important issue nowadays. This thesis presents a wearable guidance system on a pair of wearable glasses with a mobile phone for people with visual impairment. The proposed system is based on a special designed voice-marker recognition. Because people with visual impairment have difficulty searching normal 2-D barcode based markers in environments, this thesis proposed a custom color marker which is detectable in 15m maximum when its size is 400 〖cm〗^2 and containing voice information inside. Users can obtain the audio message of current location information though the system without any network connection or a database. The marker recognition can be processed in real-time on most quad-core mobile phones. In addition, to ensure safe walk experiences for people with visual impairment, multiple micro ultrasonic sensors are used to achieve obstacles detection for low power. The function of positioning and obstacles detection can work standalone or in parallel. In order to achieve low power system architecture and avoid overloading, glasses are only responsible for obtaining and transmitting data including image sequence and ultrasonic sensors values. The mobile phone processes these data to get the location and detect obstacles. The proposed system could help people with visual impairment have better experience in many environments such as bus stations or department stores, and arrive at their destination in a safe way without other’s assistance.
Tsai, Cheng-che, and 蔡政哲. "A Visually Assisted Guidance System for Visually Impaired People Passing Pedestrian Crosswalks." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/n357rz.
Full text國立中山大學
機械與機電工程學系研究所
107
Visually impaired people always experience inconvenience to manage many issues in their daily life. Crossing the road without tactile paving becomes a great challenge to the blind, who can only rely on the tactile stick. Based on this motivation, the thesis aims to develop a portable assistive guiding system using techniques of machine vision to allow the visually impaired people can always walk on the central area of the crosswalks while crossing the road. Both safety and autonomy of visually impaired people can therefore be improved. This research incorporates image processing approaches to locate the central position of the crosswalks even affected by occlusion of pedestrians and interference of shadow. In addition, statistical approaches are also applied to reduce the influence of fault detection. A vibration device is then employed to provide information of guidance for the visually impaired people. The experiments are divided into two groups, static and dynamic images, to examine performance of the proposed middle-line detection algorithm and guidance of vibration strategy. In order to consider all possible appearances of crosswalks in the image, four different conditions, head-on without occlusion, oblique without occlusion, head-on with occlusion, and oblique with occlusion, are studied. Finally, the presented assistive guiding system demonstrates promising performance to direct a healthy person with both eyes covered walking on the crosswalks to pass through a road in the real world.
(9188978), Aslihan Terzi. "THE ROLE OF NADPH OXIDASE 2 IN AXON GUIDANCE DURING ZEBRAFISH VISUAL SYSTEM DEVELOPMENT." Thesis, 2020.
Find full textReactive oxygen species (ROS) are critical for maintaining cellular homeostasis and function when produced in physiological ranges. Important sources of cellular ROS include NADPH oxidases (Nox), which are evolutionarily conserved multi-subunit transmembrane proteins. Nox-mediated ROS regulate a variety of biological processes including stem cell proliferation and differentiation, calcium signaling, cell migration, and immunity. ROS participate in intracellular signaling by introducing post-translational modifications to proteins and thereby altering their functions. The central nervous system (CNS) expresses different Nox isoforms during both development and adulthood. There is now emerging evidence that Nox-derived ROS also control neuronal development and pathfinding. Our lab has recently shown that retinal ganglion cells (RGCs) from nox2 mutant zebrafish exhibit pathfinding errors. However, whether Nox could act downstream of receptors for axonal growth and guidance cues is presently unknown. To investigate this question, we conducted a detailed characterization of the zebrafish nox2 mutants that were previously established in our group. Abnormal axon projections were found throughout the CNS of the nox2 mutant zebrafish. Anterior commissural axons failed proper fasciculation, and aberrant axon projections were detected in the dorsal longitudinal fascicle of the spinal cord. We showed that the major brain regions are intact and that the early development of CNS is not significantly altered in nox2 mutants. Hence, the axonal deficits in nox2 mutants are not due to general developmental problems, and Nox2 plays a role in axonal pathfinding and targeting. Next, we investigated whether Nox2 could act downstream of slit2/Robo2-mediated guidance during RGC pathfinding. We found that slit2-mediated RGC growth cone collapse was abolished in nox2 mutants in vitro. Further, ROS biosensor imaging showed that slit2 treatment increased growth cone hydrogen peroxide levels via mechanisms through Nox2 activation. Finally, we investigated the possible relationship between slit2/Robo2 and Nox2 signaling in vivo. Astray/nox2 double heterozygous mutant larvae exhibited decreased tectal area as opposed to individual heterozygous mutants, suggesting both Nox2 and Robo2 are required for the establishment of retinotectal connections. Our results suggest that Nox2 is part of a signal transduction pathway downstream of slit2/Robo2 interaction regulating axonal guidance cell-autonomously in developing zebrafish retinal neurons.
Sidhu, Nicole. "The Role of Repulsive Guidance Molecule b (RGMb) in the Developing Chick Visual Sytem." 2012. http://hdl.handle.net/1807/33530.
Full textLapyko, Anna, and 賴安娜. "Prototype of Cloud and Android Based Outdoor Guidance System for the Visually Impaired." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/77202072011094223330.
Full text國立交通大學
電機資訊國際學程
101
Safe navigation in non-familiar outdoor environments is a challenging activity for the blind and vision-impaired (BVI) people. This work introduces a prototype of a cloud-based outdoor assistive navigation system (COANS) for BVI people. The main goal of the system is to provide easy street navigation and help to make outdoor walks in non-familiar environment less stressful. Hardware part from the user-side includes an android-base mobile phone and an external low-cost L1 GPS receiver to improve position accuracy. Applying the technique known as Real Time Kinematic (RTK) ameliorates the issue of the user position estimation. Interaction between the application and the user is based on voice commands (user-side) and voice notifications (system-side), together with the user-friendly “shaking” and “swiping” commands. The test scenarios for the system include traffic light status detection, zebra crossing path detection and a bench discovering within a short distance from the user.
Yun, Huang Tai, and 黃泰運. "Design and Implementation of an Indoor Guidance System for the Visually Impaired Using RFID." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/46430144271007654571.
Full text國立高雄師範大學
資訊教育研究所
96
When a visually impaired person enters an unfamiliar indoor environment, he always needs a sighted person standing nearby for guidance; otherwise, he has to spend a long time exploring the environment himself. Even if he is in a familiar site, if objects in the site are moved or changed unexpectedly, he must explore the environment all over again. To address the above problems, we develop an indoor guidance system integrated with RFID devices. When the visually impaired people apply this system, they can quickly get the related information of the unfamiliar environment by the voice output of our system. With this system the visually impaired people can explore an indoor environment easily even without the guidance of normal people. Specifically, the purpose of this research is to solve problems such as location identification, searching objects near a target object, colliding with a barrier, and avoiding dangerous objects. These problems may occur when visually impaired people are in an unfamiliar environment. We take advantages of RFID(RFID,Radio Frequency Identification) technology to save/send identification data and access data repeatable. First, we stick RFID Tags onto objects in the environment for identification. The visually impaired people apply a mobile device such as PDA equipped with a RFID reader to get different information from this system. The basic process of our system is divided into four parts. First, the mobile device judges whether RFID Tags exist in the sensing area or not. Then the device sends the unique ID to the back-end server. According to different functions, the back-end server will produce different voice output data. Finally, the back-end server returns the voice output data to mobile device. Through the voice output information, visually impaired people can easily know the arrangement of the indoor environment.
Tien, Cheng-Ping, and 田正平. "The Survey of Specific Requirements and Guidance System to Cross Intersections for the Visually Impaired." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/19064453356811633537.
Full text朝陽科技大學
工業工程與管理系碩士班
96
Visually impaired people usually have met the problems in identifying the traffic signal and how to cross the street. These problems will make them failed to cross the intersection. The purpose of this study is to identify visually impaired people’s demand and build up a guidance system helping them cross the intersection safely. By using questionnaires from 218 subjects to understand requirements of visually impaired people crossing intersection, the most two requirements are lacking the signal of sound (61.0%) and unable to identify the traffic lamp signal (65.9%). A guidance system to cross intersections for the visually impaired was build up in the study. This guidance system includes two main parts: one is a mobility device carried and controlled by the user, the other is a device mounted on the pedestrian crossing light and commucated with users’ mobility device. The visually impaired people could obtain the vocal signal guidance when crossing the intersections. The experimental result from the visually impaired people showed that vocal signal guidance is more effective. The combination of both white cane and users’ mobility device at the same time, the mobility accuracy for the visually impaired people will be enhanced.
Duff, Gabriel. "Implication du récepteur aux cannabinoïdes CB2 dans le développement de la voie rétinothalamique." Thèse, 2009. http://hdl.handle.net/1866/3581.
Full textRetinal projection navigation towards their visual targets is regulated by guidance molecules and growth cone transduction mechanisms. Here, we show that cannabinoid receptor 2 (CB2R) is widely expressed throughout the visual pathway during development and in cultured retinal ganglion cells (RGCs) and cortical neurons. Both the number of filopodia and the surface area of the growth cone (GC) are modulated by CB2R activity in a PKA-dependant manner. Furthermore, DCC is required for CB2R induced morphological changes of the GC. CB2R agonists induce GC chemorepulsion. Treatments altering CB2R activity change retinal explants projections length. These effects are specific to CB2R as no changes were observed in cnr2 knockout mouse. A single intraocular injection of AM630 increases retinal projection branch length and aberrant projections were also observed. Moreover, we report defect in eye-specific segregation of retinal projections in the dLGN in cnr2-/- mice. These findings highlight the modulatory role of endocannabinoids and their CB2R during axon guidance.
Tice, Edward Roy. "A study of the perceptions of secondary students and parents of a career education curriculum in a small rural school system." Thesis, 1995. http://hdl.handle.net/1957/35013.
Full textGraduation date: 1995
Yang, Tao. "Brand and usability in content-intensive websites." Thesis, 2014. http://hdl.handle.net/1805/4667.
Full textOur connections to the digital world are invoked by brands, but the intersection of branding and interaction design is still an under-investigated area. Particularly, current websites are designed not only to support essential user tasks, but also to communicate an institution's intended brand values and traits. What we do not yet know, however, is which design factors affect which aspect of a brand. To demystify this issue, three sub-projects were conducted. The first project developed a systematic approach for evaluating the branding effectiveness of content-intensive websites (BREW). BREW gauges users' brand perceptions on four well-known branding constructs: brand as product, brand as organization, user image, and brand as person. It also provides rich guidelines for eBranding researchers in regard to planning and executing a user study and making improvement recommendations based on the study results. The second project offered a standardized perceived usability questionnaire entitled DEEP (design-oriented evaluation of perceived web usability). DEEP captures the perceived website usability on five design-oriented dimensions: content, information architecture, navigation, layout consistency, and visual guidance. While existing questionnaires assess more holistic concepts, such as ease-of-use and learnability, DEEP can more transparently reveal where the problem actually lies. Moreover, DEEP suggests that the two most critical and reliable usability dimensions are interface consistency and visual guidance. Capitalizing on the BREW approach and the findings from DEEP, a controlled experiment (N=261) was conducted by manipulating interface consistency and visual guidance of an anonymized university website to see how these variables may affect the university's image. Unexpectedly, consistency did not significantly predict brand image, while the effect of visual guidance on brand perception showed a remarkable gender difference. When visual guidance was significantly worsened, females became much less satisfied with the university in terms of brand as product (e.g., teaching and research quality) and user image (e.g., students' characteristics). In contrast, males' perceptions of the university's brand image stayed the same in most circumstances. The reason for this gender difference was revealed through a further path analysis and a follow-up interview, which inspired new research directions to unpack even more the nexus between branding and interaction design.