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Journal articles on the topic 'Vitamin D, chronic kidney disease, hemodialysis, diet'

Author: Grafiati

Published: 24 April 2022

Last updated: 30 July 2025

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1

Murkamilov, I. T., K. A. Aitbaev, V. V. Fomin, Zh A. Murkamilova, and F. A. Yusupov. "Treatment of mineral-bone disorders in chronic kidney disease." Clinical pharmacology and therapy 29, no. 4 (2020): 85–90. http://dx.doi.org/10.32756/0869-5490-2020-4-85-90.

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Mineral-bone disorders (MBD) in chronic kidney disease (CKD) manifest by hyperphosphatemia, vitamin D deficiency, overproduction of fibroblast growth factor-23, and secondary hyperparathyroidism. CKD-MBD also results in bone resorp-tion and ectopic calcification that is associated with an increased risk of cardiovascular events and mortality. Diet is the initial and obligatory approach to treatment for CKD-MBD. Sevelamer is frequently used for correction of hyperphosphatemia in patients with renal failure who present with calcification of arteries, adynamic bone disease and/or stably low serum

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Gravellone, Luciana, Maria Antonietta Rizzo, Valentina Martina, Nicoletta Mezzina, Anna Regalia, and Maurizio Gallieni. "Vitamin D Receptor Activators and Clinical Outcomes in Chronic Kidney Disease." International Journal of Nephrology 2011 (2011): 1–13. http://dx.doi.org/10.4061/2011/419524.

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Vitamin D deficiency appears to be an underestimated risk factor for cardiovascular disease in patients with chronic kidney disease. Evidence from both basic science and clinical studies supports the possible protective role of vitamin D beyond its effect on mineral metabolism. Toxicity of pharmacologic doses of active vitamin D metabolites, in particular calcitriol, is mainly due to the possibility of positive calcium and phosphorus balance. Therefore, vitamin D analogs have been developed, which suppress PTH secretion and synthesis with reduced calcemic and phosphatemic effects. Observationa

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Nurjanah, Oktika, Susaldi Susaldi, and Sumedi Sumedi. "Hubungan Kepatuhan, Derajat Hipertensi dan Status Nutrisi: Obesitas dengan Defisiensi Vitamin D pada Pasien Hemodialisis." Journal of Nursing Education and Practice 1, no. 4 (2022): 108–16. http://dx.doi.org/10.53801/jnep.v1i4.68.

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Introduction: CKD (Chronic Kidney Disease) is a gradual failure of kidney function that causes the accumulation of metabolic waste substances (uremic toxins), resulting in decreased kidney function and gradual loss of kidney function over time. Objectives: To determine the relationship between adherence, degree of hypertension, and nutritional status with vitamin d deficiency in hemodialysis patients. Method: The population of this study was all patients undergoing hemodialysis therapy in room 1 and room 2 of the Avio Prima Ciledug Hemodialysis Clinic, collecting 30 people. The sampling techni

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Shen, Yingjing. "Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease." Medicine 102, no. 43 (2023): e35811. http://dx.doi.org/10.1097/md.0000000000035811.

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Chronic kidney disease-mineral and bone disorder is a syndrome of mineral and bone metabolism abnormalities caused by chronic kidney disease. Osteoporosis is a systemic metabolic bone disease characterized by low bone mass, disruption of bone microstructure, increased brittleness, and a higher propensity for fractures. Both of these conditions significantly affect bone metabolism and substantially increase the risk of fractures. Nutritional vitamin D is an essential trace element in the human body and an important fat-soluble vitamin. One crucial physiological role of nutritional vitamin D is

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Sireesha, Vankodoth, P. Ramya Sri, and Asiya Sultana. "Comprehensive Review of CKD-MBD: From Diagnosis to Therapeutic Interventions." International Journal of Science and Healthcare Research 9, no. 3 (2024): 290–95. http://dx.doi.org/10.52403/ijshr.20240335.

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Globally, one of the most common diseases is chronic kidney disease, which is complex and varied. One of the complications associated with the advancement of chronic kidney disease is mineral bone disorders, which include biochemical and hormonal dysregulation. A number of biomarkers, including Fibroblast Growth Factor-23, klotho, phosphate, calcium, vitamin D, and PTH, have abnormal serum level variations that are central to the pathophysiology of chronic kidney disease-Mineral Bone Disorders. Biomarkers for essential elements and functionaries of chronic kidney disease-Mineral Bone Disorders

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Faisal, Artaria Tjempakasari, and Djoko Santoso. "Correlation between vitamin D level and FRAX score in chronic kidney disease patient on maintenance hemodialysis." Bali Medical Journal 13, no. 3 (2024): 1350–54. https://doi.org/10.15562/bmj.v13i3.5280.

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Background: Vitamin D (Vit-D) deficiency is common in CKD on hemodialysis patients. Vitamin D deficiency can cause decreased bone density, increasing osteoporosis and fracture risk. The World Health Organization has developed a new fracture risk assessment tool (FRAX score) that has become increasingly popular in osteoporosis diagnostics and risk of fracture assessment in many countries. This study evaluates the correlation between vitamin D level and FRAX score in end-stage renal disease (ESRD) patients on hemodialysis. Method: A cross sectional study was conducted on 68 CKD patients on routi

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Kovács, László, Éva Virágh, Dóra Balogh, Bernadette Kálmán, Zoltán Lőcsei, and Erzsébet Toldy. "Clinical evaluation of two parathyroid hormone assays in the context of vitamin D supply in chronic kidney disease." Orvosi Hetilap 154, no. 51 (2013): 2025–36. http://dx.doi.org/10.1556/oh.2013.29784.

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Introduction: Parathyroid hormone levels provide important information in chronic renal failure. Aim: To compare parathyroid hormone levels measured by two assays in correlation with vitamin D supply. Method: Parathyroid hormone and 25-hydroxi-vitamin-D were determined in 104 patients (31 patients with chronic renal failure without renal replacement therapy, 36 patients treated with peritoneal dialysis and 37 patients treated with hemodialysis). Results: Good correlation was found between results of the two parathyroid hormone methods, but the intact parathyroid hormone levels were higher than

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Mittal, SP, Harendra Singh Sandhu, and Bant Singh. "Study of Vitamin D levels in patients with Chronic Kidney Disease." Bangladesh Journal of Medical Science 17, no. 4 (2018): 652–60. http://dx.doi.org/10.3329/bjms.v17i4.38332.

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Introduction: Apart from classical functions, vitamin D has autocrine function. Autocrine function of vitamin D has a potential impact on the morbidity and mortality in the Chronic Kidney Disease patients. This study is undertaken to observe probable modality, if present, between post Hemodialysis (HD) decrease in vitamin D levels and clinical deterioration in CKD patients.Method & Material: 63 patients (32 males and 31 females) of Stage – 5 CKD were studied. There vitamin D was estimated before and after HD on first and subsequent maintenance HDs all patients with or without comorbidities

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Kumar, Sandeep, Bhagwan Das, Santosh Kumar, Abdul Manan Junejo, Rafia Memon, and Om Lal. "Vitamin D Deficiency in End-Stage Renal Disease Patients on Maintenance Hemodialysis." Pakistan Journal of Medical and Health Sciences 16, no. 1 (2022): 365–66. http://dx.doi.org/10.53350/pjmhs22161365.

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Objective: To determine the frequency of vitamin D deficiency in end stage renal disease patients on maintenance hemodialysis. Study Design: Descriptive Cross-Sectional study. Place and Duration of Study: Department of Nephrology, JPMC, Karachi, from 12th October, 2019 to 11th April 2020. Methodology: One hundred and thirty three patients were enrolled. Venous blood sample of each patient was taken and sent to the laboratory for measuring the vitamin D levels. Serum vitamin D levels <20 ng/ml was taken as vitamin D deficiency. Results: Eighty six (64.7%) were males while 47 (35.3%) were fem

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Chen, Xin, Yong-Ping Lu, Ting Luo, et al. "Free 25-Vitamin D Is Correlated with Cardiovascular Events in Prevalent Hemodialysis Patients but Not with Markers of Renal Mineral Bone Disease." Kidney and Blood Pressure Research 44, no. 3 (2019): 344–53. http://dx.doi.org/10.1159/000499878.

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Free vitamin D is the biologically active form of vitamin D. Vitamin D deficiency is associated with cardiovascular disease, the most common cause of mortality in hemodialysis patients. The goal of our current study was to investigate the relation between blood concentrations of free 25-hydroxyvitamin D with cardiovascular events in end-stage chronic kidney disease patients on hemodialysis, because this is unknown so far. We measured free vitamin D levels in 117 stable consecutive prevalent patients in September as a surrogate of vitamin D exposure during the past 6 months, and recorded the nu

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Faja, Serfa, and Amir Shoshi. "Calcium, Phosphorus and PTH in Patients with End Stage of Chronic Kidney Disease, Undergoing Hemodialysis." European Journal of Natural Sciences and Medicine 3, no. 2 (2020): 21. http://dx.doi.org/10.26417/214rmd38q.

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Renal hyperparathyroidism (rHPT) is a common complication of chronic kidney disease characterized by elevated parathyroid hormone levels secondary to derangements in the homeostasis of calcium, phosphate, and vitamin D. Patients with rHPT experience increased rates of cardiovascular problems and bone disease. The Kidney Disease: Improving Global Outcomes guidelines recommend that screening and management of rHPT be initiated for all patients with chronic kidney disease stage 3 (estimated glomerular filtration rate, - 60 mL/min/1.73 m2). Since the 1990s, improving medical management with vitami

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Khan, Md Masum Kamal, Saquiba Yesmine, MA Rashid, Rehnuma Tasmin Chowdhury, Iqbal Hasan Mahmood, and Shah Muhammad Tanvir Sumeet. "Management of Disturbances of Calcium & Phosphate Metabolism in Patients with Chronic Kidney Disease." Ibrahim Cardiac Medical Journal 2, no. 2 (2012): 37–40. http://dx.doi.org/10.3329/icmj.v2i2.52853.

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Management of chronic kidney disease-mineral bone disorder (CKD-MBD) can be difficult in patients with chronic kidney disease (CKD). This review aims to explain why the control of disturbed calcium, phosphate, parathyroid hormone and vitamin D metabolism is important in CKD patients. The available means to control these parameters include diet, phosphate binders, native Vitamin D, active Vitamin D derivatives and calcimimetics. However, no single measure is not enough and concerted efforts give the best result. Ibrahim Cardiac Med J 2012; 2(2): 37-40

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Egshatyan, L. V. "Selective vitamin D receptor activator Paricalcitol and its potential benefits in hemodialysis patients with secondary hyperparathyroidism." Meditsinskiy sovet = Medical Council, no. 10 (June 19, 2022): 132–39. http://dx.doi.org/10.21518/2079-701x-2022-16-10-132-139.

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Currently, the incidence and prevalence of chronic kidney disease (CKD) are increasing annually worldwide, and clinical data show that CKD patients commonly experience relative vitamin D insufficiency or deficiency. Secondary hyperparathyroidism (SHPT) is a common complication in patients with end-stage renal disease and it is also common in hemodialysis patients. SHPT is an adaptive and in many cases ultimately maladaptive process that develops in response to declining kidney function, impaired phosphate excretion, failure to bioactivate vitamin D and hypocalcemia. SHPT is characterized by pe

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Egshatyan, Lilit V., Natalya G. Mokrisheva, and Lyudmila Ya Rozhinskaya. "Secondary and tertiary hyperparathyroidism in chronic kidney disease." Osteoporosis and Bone Diseases 20, no. 2 (2017): 63–68. http://dx.doi.org/10.14341/osteo2017263-68.

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In the treatment of secondary hyperparathyroidism of end-stage chronic kidney disease, vitamin D receptor activation and allosteric modulators of the calcium-sensing receptor – inhibit glandular hyperplasia, reduce parathyroid hormone levels, impact on bone turnover and mineral density. But the use of calcimimetic and vitamin D analogs or mimetics did not reduce the need for parathyroidectomy for refractory hyperparathyroidism. The enlarged parathyroid gland and gland nodular transformation became refractory to medical therapy and patient need for parathyroidectomy. Tertiary hyperparathyroidis

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Lusito, Lusito, Lestariningsih Lestariningsih, Dwi Lestari Partiningrum, et al. "Vitamin D Insufficiency with Elevated ADMA and hs-CRP: A Single-center Study of Chronic Kidney Disease Patients Undergoing Hemodialysis." Indonesian Journal of Kidney and Hypertension 1, no. 2 (2024): 20–27. http://dx.doi.org/10.32867/inakidney.v1i2.134.

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Background: Vitamin D deficiency is a common issue among patients with chronic kidney disease (CKD) due to its ability to convert vitamin D into the active form of calcitriol, which is crucial for controlling cell inflammation. Low vitamin D levels are associated with increased inflammation and higher levels of biomarkers such as c-reactive protein and asymmetric dimethylarginine as an endogenous inhibitor of nitric oxide synthase. Those two combined become a specific marker for cardiovascular diseases, which become one of the common causes of CKD mortality. Objective: This study examines the

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Adiyanti, Sri Suryo, Yusra Yusra, Suzanna Immanuel, Diana Aulia, Fify Henrika, and July Kumalawati. "The Role of Neutrophil Lymphocyte Ratio , Vitamin D, and NGAL as Cardiovascular Disease Marker in Chronic Kidney Disease." eJournal Kedokteran Indonesia 9, no. 3 (2022): 192–6. http://dx.doi.org/10.23886/ejki.9.35.192-6.

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Chronic kidney disease (CKD) patients have higher risk to develop cardiovascular disease (CVD) than non-CKD patients. Neutrophil lymphocyte ratio (NLR) in CKD patients reflects inflammation status and role as complementary prognostic marker to evaluate cardiovascular risk in stage 3 to 5 CKD. High prevalence of vitamin D deficiency commonly found in CKD patients, leads to endothelial dysfunction and increase inflammation. NGAL is used as renal injury biomarker but nowadays NGAL has been known plays important role in CVD pathophysiology. CVD identification in CKD patients is necessary to obtain

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Bashir, Ahmed Muhammad, Gokhan Alici, Mohamud Mire Wabari, Abdulkamil Abdullahi Adani, and Hussein Mahdi Ahmed. "Secondary Hyperparathyroidism in Adult Chronic Hemodialysis Patients-Prevalence and Clinical Aspect." Dunya Journal of Medical Sciences 2, no. 1 (2025): 1–6. https://doi.org/10.70246/vv2t1p67.

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Background: Secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease (CKD). Aim: The exact prevalence of secondary hyperparathyroidism in chronic hemodialysis patients in Somalia is unknown. In this study, we aim to determine the prevalence of SHPT in chronic hemodialysis patients in Mogadishu, Somalia. Method: This retrospective analysis was done at Mogadishu Somali Turkey training and research hospital, Somalia's largest dialysis center. All >18-year-old hemodialysis patients from the last year were included. The research excluded parathyroidectomy and stero

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Pai, Amy Barton, and Todd A. Conner. "Oxidative Stress and Inflammation in Chronic Kidney Disease: Role of Intravenous Iron and Vitamin D." Journal of Pharmacy Practice 21, no. 3 (2008): 214–24. http://dx.doi.org/10.1177/0897190008316288.

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Cardiovascular disease (CVD) is the leading cause of death among chronic kidney disease patients (CKD). The etiology of CVD in CKD is multifactorial and increasing evidence points to the important contribution of “nontraditional” risk factors including oxidative stress and inflammation. CKD is associated with a chronic imbalance of prooxidant and antioxidant factors that results in a state of chronic inflammation. Intravenous iron supplementation has been shown to induce oxidative stress and has been associated with lipid peroxidation and DNA damage. Conversely, treatment with vitamin D analog

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Mihaylov, R., B. Pencheva, D. Stoeva, N. Marinova, S. Krivoshiev, and G. Michailov. "Determining the Levels of Vitamin D and Parathyroid Hormone in Patients on Hemodialysis." Acta Medica Bulgarica 43, no. 1 (2016): 23–29. http://dx.doi.org/10.1515/amb-2016-0003.

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Summary Vitamin D deficiency is fequently observed in chronic kidney disease. We conducted this study to determine the concentration of the above-mentioned parameters and the correlation between them in order to optimize therapy with vitamin D in patients with end-stage renal disease (ESRD) on hemodialysis. In 53 patients on hemodialysis due to ESRD, vitamin D [Calcidiol (25(OH)D], parathyroid hormone (PTH), calcium, phosphorus, albuminuria, albumin:creatinine ratio (ACR) and other parameters have been followed up. Analysis of the levels of vitamin D has been carried out by High Performance Li

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Zakharova, Irina N., Anna N. N. Kasyanova, Leonid Ya Klimov, et al. "The role of vitamin D levels in the development and progression of kidney disease: The current state of the problem. A review." Pediatrics. Consilium Medicum 1, no. 1 (2025): 44–50. https://doi.org/10.26442/26586630.2025.1.203084.

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Progressive loss of kidney function is associated with significant morbidity and mortality and is an important global health concern, given the high prevalence of chronic kidney disease (CKD). Recently, there has been an increased interest in finding new therapeutic strategies that may slow the progression of renal dysfunction. Numerous studies using various experimental models have proven that treatment with active metabolites of vitamin D can have a renoprotective effect, preventing fibrosis, apoptosis, and inflammation. In addition, vitamin D deficiency and insufficiency are common conditio

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Diah, Adiyati, and Zulkifli. "SELFCARE IN RELATION TO DIETARY COMPLIANCE FOR NUTRITION AND FLUID AMONG PATIENTS UNDERGOING HEMODIALYSIS." JURNAL MUTIARA NERS 6, no. 2 (2023): 158–71. http://dx.doi.org/10.51544/jmn.v6i2.3940.

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The dietary intake of nutrients and fluids holds paramount importance for patients afflicted with chronic kidney disease undergoing hemodialysis, as it significantly influences their overall well-being and quality of life. Mismanaged nutritional and fluid intake may lead to adverse clinical consequences, including the development of ascites and edema. Furthermore, inadequate implementation of a well-balanced nutritional and fluid regimen can result in the depletion of muscle and fat mass, thereby impacting the daily functioning of individuals grappling with chronic kidney disease. The correlat

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Saad Mzaalak Tazi, Soukaina El aasri, Saliha Chellak, and Abderrahman Boukhira. "Biological profile of secondary hyperparathyroidism in chronic renal failure patients." GSC Biological and Pharmaceutical Sciences 27, no. 2 (2024): 035–42. http://dx.doi.org/10.30574/gscbps.2024.27.2.0165.

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Secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease, especially in hemodialysis patients. It is characterized by overproduction of parathyroid hormone in response to chronic deterioration of renal function. The aim of this retrospective study was to determine the average time to develop secondary hyperparathyroidism, analyze the initial phosphocalcic profiles, and evaluate the evolution of these profiles in hemodialysis patients, following the recommendations of the KDOQI 2003 and KDIGO 2009 groups. The study included 134 hemodialysis patients from two priva

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Saad, Mzaalak Tazi, El aasri Soukaina, Chellak Saliha, and Boukhira Abderrahman. "Biological profile of secondary hyperparathyroidism in chronic renal failure patients." GSC Biological and Pharmaceutical Sciences 27, no. 2 (2024): 035–42. https://doi.org/10.5281/zenodo.12533829.

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Secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease, especially in hemodialysis patients. It is characterized by overproduction of parathyroid hormone in response to chronic deterioration of renal function. The aim of this retrospective study was to determine the average time to develop secondary hyperparathyroidism, analyze the initial phosphocalcic profiles, and evaluate the evolution of these profiles in hemodialysis patients, following the recommendations of the KDOQI 2003 and KDIGO 2009 groups. The study included 134 hemodialysis patients from two priva

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Baradaran, Azar, Zahra Hoseini, Parin Hedayati, and Reyhaneh Shirvani. "Evaluation of the relationship between neutrophil-to-lymphocyte ratio and 25-hydroxy vitamin D levels in hemodialysis patients, Isfahan, Iran." Journal of Preventive Epidemiology 6, no. 2 (2021): e26-e26. http://dx.doi.org/10.34172/jpe.2021.26.

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Introduction: Chronic low-grade inflammation is a comorbid factor in Chronic kidney disease (CKD), and especially in chronic dialysis patients. Recently, neutrophil-to-lymphocyte ratio (NLR), which is very available and affordable, has emerged as an inflammatory index in many disorders such as CKD. Several studies also have shown the anti-inflammatory effects of vitamin D, and scientists believe that we must prevent vitamin D deficiency in CKD patients. Vitamin D supplementation may decrease mortality and morbidity in end-stage renal disease (ESRD) patients. Objectives: There are few studies o

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Bulut, Nilüfer, Mehmet Çağatay Taşkapan, and Hülya Taşkapan. "THE EFFECT OF VITAMIN D LEVELS ON INFLAMMATION IN PATIENTS WITH CHRONIC RENAL FAILURE." e-Journal of New World Sciences Academy 15, no. 4 (2020): 166–78. http://dx.doi.org/10.12739/nwsa.2020.15.4.1b0100.

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It is suggested that a number of environmental and genetic factors trigger the formation of progressive kidney damage and complications. One of these factors is inflammation, it occurs as a result of a series of mechanisms included within a number of cytokines. Vitamin-D, IL-6, PCT and hs-CRP are also valuable biomarkers in terms of mortality in dialysis patients in this sense. Vitamin D deficiency is common in patients with chronic kidney disease (CKD) and is associated with inflammation. In recent years, some randomized controlled trials have revealed the effect of Vitamin D on inflammation

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Diana, Laila Ramatillah. "SYSTEMATIC REVIEWS: COMPLICATION OF DISEASE AND RISK OF DEATH ON CHRONIC KIDNEY PATIENTS NON-HEMODIALYSIS." iajps 03, no. 10 (2016): 1291–96. https://doi.org/10.5281/zenodo.167865.

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<strong><em>Introduction</em></strong><em>: Chronic Kidney Disease (CKD) is a condition of reducing renal function in excreting metabolism residual. Dietary habit, </em><em>using of drugs in a long time, losing of body fluid, infection, a complication of disease and family history</em><em> are the factors of end-stage renal disease (ESRD), while ESRD becomes one of the largest public health problems in the world. </em> <strong><em>Objective :</em></strong> <em>T</em><em>o evaluate </em><em>the complication of disease and </em><em>risk of death in chronic kidney disease (CKD) </em><em>non-</em>

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Tallman, Dina, Sharmela Sahathevan, Tilakavati Karupaiah, and Pramod Khosla. "Egg Intake in Chronic Kidney Disease." Nutrients 10, no. 12 (2018): 1945. http://dx.doi.org/10.3390/nu10121945.

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Patients with chronic kidney disease (CKD) are often instructed to adhere to a renal-specific diet depending on the severity and stage of their kidney disease. The prescribed diet may limit certain nutrients, such as phosphorus and potassium, or encourage the consumption of others, such as high biological value (HBV) proteins. Eggs are an inexpensive, easily available and high-quality source of protein, as well as a rich source of leucine, an essential amino acid that plays a role in muscle protein synthesis. However, egg yolk is a concentrated source of both phosphorus and the trimethylamine

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Heaf, James Goya. "Chronic KidneY Disease-Mineral Bone Disorder in the Elderly Peritoneal Dialysis Patient." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 35, no. 6 (2015): 640–44. http://dx.doi.org/10.3747/pdi.2014.00339.

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Purpose The purpose of this paper was to review the literature concerning the treatment of chronic kidney disease-mineral bone disorder (CKD-MBD) in the elderly peritoneal dialysis (PD) patient. Results Chronic kidney disease-mineral bone disorder is a major problem in the elderly PD patient, with its associated increased fracture risk, vascular calcification, and accelerated mortality fracture risk. Peritoneal dialysis, however, bears a lower risk than hemodialysis (HD). The approach to CKD-MBD prophylaxis and treatment in the elderly PD patient is similar to other CKD patients, with some imp

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Rytel, Adam, Kacper Żelek, Magdalena Mosakowska, and Stanisław Niemczyk. "Acute and delayed consequences of vitamin D intoxication: two case reports." Lekarz Wojskowy 101, no. 2 (2023): 151–54. http://dx.doi.org/10.53301/lw/154796.

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Background: Vitamin D intoxication (VDI) is a rare cause of kidney injury, but it can have fatal consequences. We would like to present two cases of patients in whom high doses of vitamin D intake led to significant health problems. Case Presentation: The first case is a 68-year-old woman taking approximately 20,000 IU of vitamin D daily. On admission, laboratory tests showed elevated renal function parameters, hypercalcemia, and elevated serum vitamin D concentration. The second case was a 71-year-old man intoxicated with vitamin D two and a half years earlier, as a consequence the patient wa

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Naser, Ola A., Shatha Q. Al-Temimi, Hanaa S. Kadhum, et al. "Evaluation of some biomarkers (phosphorus, Parathyroid hormone, Calcium, vitamin D) in patient's serum with chronic kidney disease (CKD)." Journal Port Science Research 7, issue (2024): 421–25. http://dx.doi.org/10.36371/port.2024.special.34.

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Background chronic kidney disease (CKD) can be defined as abnormalities either in kidney structure or function by decreasing glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m² for at least 3 months. it is considered to be a major medical problem, especially in developing countries and emerging economies. The study aims to measure biochemical markers (calcium, phosphorus, vitamin D, and PTH) in patients with CKD and healthy control, also finding out the effect of CKD on formation active form of vitamin D. Methods: This study includes (90) individuals (60) patients (30 males and 30

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Dr Madhumitha M, Dr Devika S Pillai. "Oral Health Needs of Chronic Kidney Disease Patients on Hemodialysis - A Clinical Retrospective Study." Cuestiones de Fisioterapia 54, no. 3 (2025): 1717–23. https://doi.org/10.48047/rd0g5d98.

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Background: Chronic kidney disease patients under hemodialysis and their association with oral health changes have been reported in many studies. Patients who have CKD will have an alteration in the calcium and Vitamin D homeostasis which can show alterations in osteoblastic-osteoclastic mechanisms which can also affect the maxillofacial region. Aim and Objectives: This study aims to assess the oral health needs of patients with chronic kidney disease undergoing hemodialysis.The objective of the study is to assess oral health changes in CKD patients and effect of oral infection on renal parame

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Fatima, Zoha, Ujala Abdul Rashid, Umara Nasim, and Hafiza Amina Muattar. "Melody of sleep by sun: Association between serum vitamin D levels and sleep quality in ESRD patients." Journal of Shifa Tameer-e-Millat University 6, no. 1 (2023): 25–31. http://dx.doi.org/10.32593/jstmu/vol6.iss1.233.

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Background: Hemodialysis (HD) is a commonly employed treatment modality for chronic kidney disease (CKD) patients. It is also closely related to the sleep-wake cycle. It has both sleep-improving and deteriorating results. Sleep regulation is tightly coupled to vitamin D; hence, its deficiency might impact the duration and quality of sleep. This study intends to evaluate the association between sleep quality and serum vitamin D levels in HD patients. Objective: To assess the quality of sleep in patients with ESRD on routine HD and determine the association of vitamin D deficiency with sle

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Yayo, Sagou Eric, Yao Epse Yapo Carine Mireille, Kadio Morel Kouacou, Melissa Nanihio, and Asseypo Marie-Laure Hauouhot. "Research on a protective effect of Vitamin D in the context of COVID-19 in adults on West African hemodialysis." International Journal of Clinical Biochemistry and Research 11, no. 4 (2025): 254–59. https://doi.org/10.18231/j.ijcbr.2024.038.

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Chronic kidney disease is a worldwide disease with an estimated prevalence of 10% in 2020. In Côte d'Ivoire, the prevalence of this disease is not well known, but hospital studies show prevalences of 7 to 46%. In 2020, hemodialysis patients are particularly at risk of contracting COVID-19. Studies have shown that vitamin D supplementation can not only reduce the risk of getting acute respiratory infections, but has also been associated with a lower susceptibility to severe COVID-19. To this end, a study was undertaken to assess the impact of the pandemic on hemodialysis patients in the public

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Ristic-Medic, Danijela, Marija Takic, Biljana Pokimica, et al. "Dietary Omega-3 PUFA Intake in Patients with Chronic Kidney Disease: The Association with Vitamin D Deficiency, Intima–Media Thickness and Blood Pressure." Journal of Clinical Medicine 13, no. 18 (2024): 5593. http://dx.doi.org/10.3390/jcm13185593.

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Background/Objectives: Numerous risk factors associated with development of cardiovascular disease (CVD) have been unfavorably altered in patients with chronic kidney disease (CKD). Low omega-3 polyunsaturated fatty acid (PUFA) intake and vitamin D deficiency are potential cardiometabolic risk factors in patients with CKD. The aim of this study was to evaluate dietary intake and status of omega-3 PUFA and vitamin D in pre-dialysis and hemodialysis patients and to examine the association of dietary α-linolenic acid (ALA) and fish consumption with blood pressure and carotid intima–media thicknes

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Hryciuk, Maksymilian, Zbigniew Heleniak, Sylwia Małgorzewicz, et al. "Assessment of Vitamin D Metabolism Disorders in Hemodialysis Patients." Nutrients 17, no. 5 (2025): 774. https://doi.org/10.3390/nu17050774.

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Background: Patients with end-stage chronic diseases, especially those undergoing hemodialysis (HD), often experience mineral bone disease (MBD), leading to hypocalcemia, hyperphosphatemia, and elevated parathyroid hormone (PTH). Vitamin D deficiency and metabolism disorders are also common, resulting from impaired conversion of 25(OH)D3 to its active form, 1,25(OH)2D3, and reduced inactivation to 24,25(OH)2D3. This study aimed to assess the levels of 25(OH)D2, 25(OH)D3, 24,25(OH)2D3, 3-epi-25(OH)D3, and the vitamin D metabolism ratio (VMR) in patients with maintenance HD. Methods: A cross-sec

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Rani, Dr Malepati Sandhya. "A PROSPECTIVE COHORT STUDY ON THE EPIDEMIOLOGICAL, ETIOLOGICAL AND CLINICAL PROFILE OF HEMODIALYSIS PATIENTS: AN EXPLORATION OF MANAGEMENT STRATEGIES AND QUALITY OF LIFE IN A TERTIARY CARE TEACHING HOSPITAL." Indian Journal of Health Care Medical & Pharmacy Practice 06, no. 01 (2025): 41–48. https://doi.org/10.59551/ijhmp/25832069/2025.6.1.70.

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Hemodialysis is a life-saving procedure for patients with chronic kidney disease who have progressed to end-stage renal disease. This prospective cohort study aims to analyze the epidemiological, etiological, and clinical profiles of hemodialysis patients while assessing management strategies and their impact on quality of life. Data were collected from 120 patients undergoing hemodialysis, comprising 79 males (65.83%) and 41 females (34.17%). The highest incidence was observed in the 50–60 years age group (27.5%). Hypertension was the leading cause (55%), followed by diabetes mellitus. Diagno

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Jerbi, Mouna, Hiba Ghabi, Hanene Gaied, et al. "Cholecalciferol therapy; is it the gold standard for vitamin D deficiency and mineral disorders in hemodialysis?" Journal of Renal Endocrinology 7, no. 1 (2020): e09-e09. http://dx.doi.org/10.34172/jre.2021.09.

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Introduction: Vitamin D deficiency is frequently observed among dialysis patients. Previous studies suggested that 50 to 90% of end-stage renal disease patients are deficient in vitamin D. In Tunisia, studies regarding hypovitaminosis D in patients on dialysis are not numerous. Actually, many data support the use of native vitamin D in hemodialysis (HD) patients. In Tunisia, using native vitamin D is not part of therapeutic habits of all dialysis centers. Objectives: The aim of this study was to determine the prevalence of vitamin D deficiency in patients with chronic kidney disease stage 5 un

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Hussein, Amer Jihad, Jawad Ibrahim Rasheed, and Ban Mezher Noaman. "Prevalence of Hyperparathyroidism among Dialysis Patients in Baghdad Teaching Hospital." International Journal of Health Systems and Medical Sciences 3, no. 4 (2024): 330–38. http://dx.doi.org/10.51699/ijhsms.v3i4.127.

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Chronic kidney disease is common due to the high prevalence of its main causes. Many pathological changes occur in these patients. Hyperparathyroidism is one of the most common pathologies reported in chronic kidney disease patients. High prevalence rates have been reported worldwide in previous studies, and different factors have been implicated to be associated with Hyperparathyroidism. The aim of this study is to assess the prevalence of hyperparathyroidism among Iraqi patients with chronic kidney disease on hemodialysis therapy and to identify the factors associated with hyperparathyroidis

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Adhikary, Laxman Prasad, and Aarjan Khanal. "Outcome of supplementation of vitamin D on intact parathyroid hormone level in chronic kidney disease patients." Journal of Kathmandu Medical College 8, no. 2 (2019): 51–54. http://dx.doi.org/10.3126/jkmc.v8i2.28164.

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Background: Secondary hyperparathyroidism is present in majority of patients with estimated glomerular filtrate rate less than 60 mL/min/1.73 m2. Sustained elevated parathyroid hormone level can cause osteitis-fibrosa-cystica, fracture, hypercalcemia, hyperphosphatemia, and calciphylaxis. Kidney Disease Improving Global Outcome guidelines for Chronic Kidney Disease Mineral and Bone Disorder 2017 recommends treatment with calcitriol or vitamin D analogue if parathyroid hormone level is progressively increasing and remains persistently above the upper limit despite correction of modiﬁable factor

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Valdivielso, José M., Diego Rodríguez-Puyol, Julio Pascual, et al. "Atherosclerosis in Chronic Kidney Disease." Arteriosclerosis, Thrombosis, and Vascular Biology 39, no. 10 (2019): 1938–66. http://dx.doi.org/10.1161/atvbaha.119.312705.

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Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality, mainly from cardiovascular causes. The association between CKD on hemodialysis and accelerated atherosclerosis was described >40 years ago. However, more recently, it has been suggested that the increase in atherosclerosis risk is actually observed in early CKD stages, remaining stable thereafter. In this regard, interventions targeting the pathogenesis of atherosclerosis, such as statins, successful in the general population, have failed to benefit patients with very advanced CKD. This raises the is

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N S, Soumya, Suresh U. Kadli, Gopal Das C M, Manjunath Rao S V, and Sharath B V. "Oxidant and Antioxidant Imbalance in Urolithiasis Patients." Indian Journal of Emergency Medicine 7, no. 3 (2021): 15–20. http://dx.doi.org/10.21088/ijem.2395.311x.7321.2.

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Disturbances in mineral metabolism are commonly seen in patients with chronic renal failure. But there are very few studies on their prevalence in Indian dialysis population. Aim: To know the prevalence of secondary hyperparathyroidism in patients with stage 5 chronic kidney disease on maintenance hemodialysis. Settings and Design: Hospital based cross sectional study. Methods and Material: This study was done on 85 patients undergoing maintenance hemodialysis for > six months. and data was collected between January 2018 and December 2018, for a period of one year.Patients were examined for

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Rangan, Gopala K., Kristina G. Schwensen, Sheryl L. Foster, Mayuresh S. Korgaonkar, Anthony Peduto, and David C. Harris. "Chronic effects of dietary vitamin D deficiency without increased calcium supplementation on the progression of experimental polycystic kidney disease." American Journal of Physiology-Renal Physiology 305, no. 4 (2013): F574—F582. http://dx.doi.org/10.1152/ajprenal.00411.2012.

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Increasing evidence indicates that vitamin D deficiency exacerbates chronic kidney injury, but its effects on renal enlargement in polycystic kidney disease (PKD) are not known. In this study, male Lewis polycystic kidney disease (LPK) rats received a normal diet (ND; AIN-93G) supplemented with or without cholecalciferol (vitamin D-deficient diet, VDD; both 0.5% calcium), commenced at either postnatal week 3 (until weeks 10–20; study 1) or from week 10 (until week 20; study 2). Levels of 25-hydroxy vitamin D were reduced in groups receiving the VDD (12 ± 1 nmol/l vs. 116 ± 5 in ND; P < 0.00

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Villa-Bellosta, Mahillo-Fernández, and Ortíz. "Questioning the Safety of Calcidiol in Hemodialysis Patients." Nutrients 11, no. 5 (2019): 959. http://dx.doi.org/10.3390/nu11050959.

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Background. Epidemiological studies have suggested a survival benefit for hemodialysis patients on paricalcitol or calcitriol, but nutritional vitamin D supplementation of patients already on vitamin D receptor (VDR) activators is controversial. Methods. This observational retrospective cohort study was conducted with prospectively collected data from all consecutive patients with chronic kidney disease (CKD) who underwent hemodialysis under routine clinical practice conditions for two years. Results. Of the 129 patients, 89 were treated with calcidiol, paricalcitol, and/or calcitriol. The pat

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Tom, Rose, and Jyothi Mariam Idiculla. "A Curious Case of Hypervitaminosis D-related Hypercalcemia." Journal of the Indian Academy of Geriatrics 19, no. 4 (2023): 273–75. http://dx.doi.org/10.4103/jiag.jiag_51_23.

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Abstract Hypercalcemia can manifest with various symptoms and poses diagnostic challenges due to its multifactorial etiology. This case highlights a 74-year-old patient with hypercalcemia of complex origin. The patient had a history of chronic liver disease, chronic kidney disease, and a previous episode of hypercalcemia associated with excessive oral Vitamin D intake. On admission, the patient presented with disorientation and increased drowsiness. Further evaluation revealed persistently high serum calcium levels, low parathyroid hormone levels, and elevated levels of Vitamin D. Investigatio

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Naber, Tania, and Sharad Purohit. "Chronic Kidney Disease: Role of Diet for a Reduction in the Severity of the Disease." Nutrients 13, no. 9 (2021): 3277. http://dx.doi.org/10.3390/nu13093277.

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Chronic kidney disease affects ~37 million adults in the US, and it is often undiagnosed due to a lack of apparent symptoms in early stages. Chronic kidney disease (CKD) interferes with the body’s physiological and biological mechanisms, such as fluid electrolyte and pH balance, blood pressure regulation, excretion of toxins and waste, vitamin D metabolism, and hormonal regulation. Many CKD patients are at risk of hyperkalemia, hyperphosphatemia, chronic metabolic acidosis, bone deterioration, blood pressure abnormalities, and edema. These risks may be minimized, and the disease’s progression

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Văcăroiu, Ileana Adela, Filip Calangiu, Georgiana Tănase, et al. "Biomarkers Involved in the Mineral-Bone Disorders Secondary to Chronic Hemodialysis." Internal Medicine 19, no. 4 (2022): 17–25. http://dx.doi.org/10.2478/inmed-2022-0225.

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Abstract Introduction. Chronic kidney disease (CKD) is one of the most prevalent public health problems of the elderly population. End-Stage Renal Disease (ESRD)’s most common treatment is dialysis. There are some dissimilarities between the sexes that are apparent in the status and the possible outcomes of CKD. This study aims to shed some light on these somewhat overlooked wwwvariations and their implications. Materials and methods. We conducted an observational study on subjects with CKD, undergoing hemodialysis for at least 2 years. For participation, we selected an equal number of men and

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Sagou, Yayo Eric, Kouacou Kadio Morel, Yao-Yapo Carine Mireille, et al. "Vitamin D Status in Supplemented Hemodialysis Patients." International Journal of Biochemistry Research & Review 33, no. 6 (2024): 420–26. http://dx.doi.org/10.9734/ijbcrr/2024/v33i6924.

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Introduction: Chronic kidney disease (CKD) causes decreased activity of the enzyme 1-alpha-hydroxylase and calcitriol deficiency with mineral and bone metabolism disorders or secondary hyperparathyroidism. Anticipation of the occurrence of these complications implies the systematic supplementation of all hemodialysis patients, with monitoring of biological parameters. It is in this context that this study was carried out, the general objective of which was to establish the profile of vitamin D concentration in hemodialysis and Ivorian public sector supplemented patients in Abidjan. Patients an

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Levy, Ronen, and Anca Gal-Moscovici. "Renal Osteodystrophy in Peritoneal Dialysis: Special Considerations." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 28, no. 2_suppl (2008): 11–19. http://dx.doi.org/10.1177/089686080802802s03.

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Bone disease is one of the most challenging complications in patients with chronic kidney disease. Today, it is considered to be part of a complex systemic disorder manifested by disturbances of mineral metabolism and vascular calcifications called chronic kidney disease – mineral bone disorder (CKD-MBD). The term renal osteodystrophy is reserved to define the specific bone lesion in CKD-MBD, whose spectrum ranges from high turnover to low turnover disease. Phosphate retention, decreased serum calcium, and 1,25-dihydroxy vitamin D synthesis are involved in the pathogenesis of high bone turnove

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da Silva, Bruno Ramos, Nyara Anielly Cabral Cantanhede, Indyara Dolores Santos Dias, Beatriz Castro Sousa Rosa, Juliana Moreira da Silva Cruvel, and Vanessa Farias Louseiro. "Biochemical changes: alert for mineral and bone disorders in children and adolescents with chronic kidney disease undergoing hemodialysis." Journal of Renal Endocrinology 10 (January 1, 2024): e25149. https://doi.org/10.34172/jre.2024.25149.

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Introduction: Mineral and bone disorder is a clinical condition characterized by biochemical alterations, bone abnormalities, and vascular calcification. Objectives: To analyze the biochemical alterations involved in mineral and bone disorder in children and adolescents with chronic kidney disease (CKD) undergoing hemodialysis at a University Hospital in Maranhão. Materials and Methods: Analytical longitudinal study conducted at the Nephrology Unit of the University Hospital of the Federal University of Maranhão. Data collection was performed through sociodemographic questionnaires, electronic

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Ankin, M. L., T. M. Petryk, V. O. Ladyka, and S. L. Dudar. "Long Bone Fractures and Mineral-Bone Disorders in Patients with Chronic Kidney Disease Treated with Hemodialysis." TERRA ORTHOPAEDICA, no. 4(115) (April 27, 2023): 43–52. http://dx.doi.org/10.37647/0132-2486-2022-115-4-43-52.

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Background. At the turn of the 20th and 21st centuries, the world community was faced with a global problem that has not only medical, but also great social economic significance – a pandemic of chronic non-communicable diseases that annually claim millions of lives, lead to severe complications associated with disability and the need for high-cost treatment. Among them is chronic kidney disease (CKD), which occupies an important place due to its significant prevalence in the population, a sharp decrease in the quality of life, high mortality of patients, and which leads to the need for expens

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