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Dissertations / Theses on the topic 'Vitamin D Metabolism'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 January 2023

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1

Hall, Judith. "Physiology and pathophysiology of vitamin D metabolism." Thesis, University of Newcastle upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377459.

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2

Bitler, Chad. "Vitamin D and Markers of Glucose Metabolism." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1416231511.

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3

Asano, Lisa. "Vitamin D metabolite, 25-Hydroxyvitamin D, regulates lipid metabolism by inducing degradation of SREBP/SCAP." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225512.

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4

Turner, Andrew. "Vitamin D metabolism in an In Vitro mineralisation model /." Title page and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09SB/09sbt9438.pdf.

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5

Laird, Eamon John. "Vitamin D status and metabolism : implications for bone health." Thesis, Ulster University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.674922.

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In addition to its established role in bone health, vitamin D (2S(OH)D) may also have a role in modulating immune function and early life development. Despite recent advances, there is a lack of consensus with regards to the optimal vitamin D cut-offs for multiple health outcomes and this uncertainty is further compounded by the wide measurement variability for the vitamin. Consequently, the work described in this thesis aimed to explore these areas of controversy. Using data from ongoing studies at the University of Ulster, a comparison study (n 131), of vitamin D status in the two most widel

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6

KELLY, MICHAEL ALAN. "CHARACTERIZATION OF RECEPTORS AND BINDING PROTEINS FOR THE ACTIVE METABOLITES OF VITAMINS A AND D IN NORMAL AND RESISTANT CELLS (PRIMATE RESEARCH)." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/183919.

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Involvement of Cellular Retinoic Acid (CRABP) or Retinol (CRBP) Binding Proteins and 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) receptors in the response of cultured cells to retinoic acid and 1,25(OH)₂D₃ was examined. A new method for saturation analysis of CRABP and CRBP was applied to human tumors, human neuroblastoma cells, which retinoic acid causes to differentiate, and a bioselected subline resistant to retinoic acid. These data suggest that CRABP may not mediate cell differentiation by retinoic acid. In other studies, 1,25(OH)₂D₃ receptors and bioresponses were characterized in cultured pr

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7

Osman, O. M. "Clinical and experimental studies on vitamin D and PTH metabolism." Thesis, University of Newcastle Upon Tyne, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382572.

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8

Anderson, Paul Hamill. "The regulation of Vitamin D metabolism in the kidney and bone." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09pha5486.pdf.

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Includes bibliographical references (leaves 226-273.) Investigates the regulation of the expression of CYP27B1, CYP24 and vitamin D receptor (VDR) mRNA, both in the bone and in the kidney, with the aim to determine whether the regulation of the vitamin D metabolism in the bone is independent from that in the kidney. The effects of age, dietary calcium and vitamin D status on the expression of these genes in both the kidney and the bone, as well as on a number of biochemical factors known to regulate the renal metabolism of 1,25D, such as PTH, calcium and 1,25D itself, were examined. CYP27B1 mR

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9

Bashir, S. E. O. "Studies of vitamin-D and mineral metabolism in health and disease." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375130.

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10

Kusudo, Tatsuya. "Structure-function analysis of cytochromes P450 involved in vitamin D metabolism." Kyoto University, 2004. http://hdl.handle.net/2433/147749.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第10900号<br>農博第1406号<br>新制||農||890(附属図書館)<br>学位論文||H16||N3911(農学部図書室)<br>UT51-2004-G747<br>京都大学大学院農学研究科食品生物科学専攻<br>(主査)教授井上國世, 教授大東肇, 教授伏木亨<br>学位規則第4条第1項該当

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11

Outila, Terhi. "The effect of vitamin D status on calcium and bone metabolism." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/maa/skemi/vk/outila/.

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12

Greer, Ristan M. "Calcium, vitamin D and vitamin A metabolism in cystic fibrosis : implications of gender differences and disease severity /." St. Lucia, Qld, 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18007.pdf.

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13

Cunningham, J. "Investigation of the effect of acidosis on the metabolism of vitamin D." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382500.

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14

Hosseinpour, Fardin. "Cytochrome P450 Enzymes in the Metabolism of Vitamin D₃." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5242-6/.

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15

Bass, Joseph. "The role of the vitamin D receptor in skeletal muscle protein metabolism." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/40166/.

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16

Naja, Roy Pascal. "The role of Vitamin D metabolic enzymes in bone development and repair /." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115860.

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The CYP27B1 enzyme that synthesizes 1alpha,25-(OH) 2D, is expressed in chondrocytes, suggesting that local production of 1alpha,25-(OH)2D could play an autocrine or paracrine role in the differentiation of these cells. To test this hypothesis, we have engineered mutant mice that do not express the Cyp27b1 gene in chondrocytes. This led to increased width of the hypertrophic zone of the growth plate at E15.5, increased bone mass in neonatal long bones, and increased expression of the chondrocytic differentiation markers Indian Hedgehog and PTH/PTHrP receptor. VEGF mRNA levels were decreased, ac

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17

Faria, Marcela Romanini. "Sensibilidade à insulina e metabolismo oxidativo de cordeiros provenientes de ovelhas suplementadas com altas doses de vitamina D no período pré-parto." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-23022018-121512/.

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Para avaliar o efeito da suplementação parenteral com vitamina D sobre a sensibilidade à insulina, metabolismo oxidativo e energético, foram utilizados 29 cordeiros recém-nascidos, mestiços (Santa Inês x Dorper) e hígidos. Estes animais foram distribuídos em quatro grupos, DD- cordeiros filhos de ovelhas suplementadas com 70.000 UI/kg de vitamina D, pela via IM, no 108o dia da gestação e que também receberam suplementação com 24 horas de vida; DC cordeiros filhos de ovelhas suplementadas com a mesma dose e no mesmo dia de gestação e que não receberam vitamina D; CD- cordeiros filhos de ovelha

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18

Romeu, Montenegro Karina. "The impact of Vitamin D on Muscle Metabolism, Bioenergetic Responses and Exercise Performance." Thesis, Curtin University, 2021. http://hdl.handle.net/20.500.11937/82588.

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This PhD thesis describes the effects of Vitamin D on skeletal muscle and includes details of two main research projects. The first study validated a physiologically significant effect of VitD3 in proliferation, differentiation, protein synthesis and mitochondrial metabolism in primary human skeletal muscle cells, in cell culture. The second study demonstrated that VitD3 supplementation does not result in additional benefits on muscle strength, power, resting metabolic rate and body composition in VitD sufficient physically active adults.

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19

Walz, Nikita Lee. "The association between Vitamin D and clinical IVF outcomes, and the in vitro effects of Vitamin D on granulosa cell steroidogenesis and metabolism." Thesis, Curtin University, 2021. http://hdl.handle.net/20.500.11937/85768.

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In recent years, studies have investigated the clinical importance of VitD levels in human fertility, but little is known about how VitD impacts women undergoing IVF or reproductive cells at the molecular level. This study has demonstrated that VitD significantly impacts the development of blastocysts and key molecular pathways involved in steroidogenesis and cellular metabolism. In the future these findings could help us improve clinical procedures in IVF to optimise patient clinical outcomes.

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20

Pathak, Kaveri. "Energy metabolism in obesity: Role of vitamin D status, cold exposure and leucine supplementation." Thesis, Curtin University, 2016. http://hdl.handle.net/20.500.11937/65387.

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We studied adaptive thermogenesis, both diet and cold-induced, in the setting of vitamin D status and leucine supplementation. Vitamin D supplementation did not increase fat loss, but higher 25OHD favoured metabolic flexibility. Cold exposure increased thermogenesis only in those with metabolic syndrome. Skin blood flow strongly predicted RMR and RQ. Leucine supplementation had no added effect, over caloric restriction but incidental improvements in 25OHD increased loss of fat mass and retained skeletal muscle mass.

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21

Wu, Julie C. Y. "Cellular analysis of calbindin and calbindin mRNA expression in chick small intestine." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319552.

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22

Roy, Stéphane. "Regulation of 1,25 dihydroxyvitamin D3-24-hydroxylase gene expression." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=34441.

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The first three studies in this thesis address the mechanism for the aberrant fall in serum 1,25-dihydroxyvitamin D$ sb3$ (1,25-(OH)$ sb2$D$ sb3 rbrack$ and increase in renal 1,25-(OH)$ sb2$D$ sb3$-24-hydroxylase(24-hydroxylase) activity in X-linked hypophosphatemic mice (Hyp). The 24-hydroxylase is the first enzyme in the C-24 oxidation pathway that degrades the vitamin D hormone to its final inactivation product, calcitroic acid. We demonstrated that: (i) the aberrant increase in 24-hydroxylase activity in Pi-deprived Hyp mice is specific to the kidney and is the result of an increase in enz

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23

Pereira, Giselle Adriana de Paiva. "Efeito da suplementação de cálcio e vitamina D no metabolismo mineral ósseo de mulheres na pós-menopausa com osteoporose." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-08062009-230251/.

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Introdução Atualmente a osteoporose é a doença mais freqüente do metabolismo ósseo. Diversos nutrientes estão relacionados com a massa óssea, com destaque para o cálcio e a vitamina D. Apesar de 80 a 90% dos estoques de vitamina D serem provenientes da síntese cutânea, estudos mostram que mesmo em países ensolarados a deficiência de vitamina D é muito comum. Considerando que a dieta da população brasileira tem se mostrado muitas vezes inadequada com relação ao consumo do cálcio e vitamina D, a suplementação desses componentes pode ser necessária em indivíduos que apresentam alterações no meta

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24

Mayengbam, Shyamchand S. "Characterization, quantification, and in vivo effects of vitamin B6 antagonists from flaxseed on amino acid metabolism in a rodent model of moderate vitamin B6 deficiency." ACS Publications, 2014. http://hdl.handle.net/1993/30741.

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Vitamin B6, or more specifically the active form pyridoxal 5ʹ-phosphate (PLP), plays a crucial role as a cofactor for numerous enzymes linked to carbohydrate, fatty acid, and amino acid metabolism. There is a high prevalence of moderate vitamin B6 deficiency in the population that may be further exacerbated through the ingestion of vitamin B6 antagonists present in the food supply. For example, flaxseed contains the anti-pyridoxine factor 1-amino D-proline (1ADP) in the form of a dipeptide called linatine. In order to address these issues, the current study was designed to: 1) characterize and

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25

Abouelmaaty, Abdelgawad Mohamed [Verfasser], and Stefan [Akademischer Betreuer] Wölfl. "Reprogramming of Basic Cellular Metabolism by Vitamin D in Tumor Cells / Mohamed Abouelmaaty Abdelgawad ; Betreuer: Stefan Wölfl." Heidelberg : Universitätsbibliothek Heidelberg, 2018. http://d-nb.info/1177252562/34.

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26

Macoritto, Michael. "Mechanisms of vitamin D receptor and retinoid X receptor mediated hormone resistance and cell differentiation in normal and cancer cells." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111887.

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Vitamin D is a precursor to a steroid hormone, 1,25 dihydroxyvitamin D (1,25(OH)2D). After its discovery and the characterization of its receptor, the vitamin D receptor (VDR), it was initially thought only to be involved in calcium homeostasis, but further research revealed an important role for vitamin D in the regulation of cell growth and differentiation of such cells as osteoblasts and bone marrow adipocytes. 1,25(OH)2D has also been shown to be a strong inhibitor and pro-differentiator of keratinocytes. The anti-proliferative and pro-differentiative properties of this hormone have led to

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27

Lönnbom, Ulrika. "Riskläkemedel för vitamin D-brist : Handläggning av patienter i Kalmar län." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-36038.

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Bakgrund: Det finns läkemedel som ger ökad risk för vitamin D-brist. En kartläggningsstudie av hur patientgrupper med olika riskläkemedel hanteras i Landstinget i Kalmar län har inte gjorts tidigare. En sådan studie är önskvärd, för att få en nulägesanalys och öka medvetenheten bland hälso-och sjukvårdspersonal om hur läkemedel påverkar D-vitaminstatus. Syfte: Syftet var att undersöka omfattningen av ordinerade riskläkemedel hos samtliga patienter, samt hos patientgruppen ≥75år och hur dessa handläggs avseende ordination av supplementering (samtidig behandling med läkemedel innehållande vitami

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28

Richts, Björn [Verfasser]. "Vitamin B6 metabolism and underground metabolic routes in the Gram-positive bacterium Bacillus subtilis / Björn Richts." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://d-nb.info/1237633621/34.

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29

Bonnet, Laurianne. "Régulation du métabolisme adipocytaire de la vitamine D : effet de l'obésité et d'une supplémentation en vitamine D." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0609/document.

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La VD (VD) est impliquée dans de nombreux processus physiologiques, dont le contrôle de certains paramètres de la biologie du tissu adipeux, son site principal de stockage. Ainsi elle y exerce des effets anti-inflammatoires et métaboliques forts, mais de nombreux aspects de ces régulations n’ont jamais été étudiés. Le but de cette thèse est d’avancer dans la connaissance de l’interrelation entre la VD, le tissu adipeux et l’obésité.Dans un premier temps, nous avons donc mis en évidence que la VD limitait l’expression de 3 miRs (miR-146a, miR-150 et miR-155) en inhibant la voie de signalisation

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Željka, Savić. "Uticaj statusa vitamina D na metaboličku aktivnost kosti i koštanu masu kod bolesnika sa alkoholnom cirozom jetre." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2014. https://www.cris.uns.ac.rs/record.jsf?recordId=89494&source=NDLTD&language=en.

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Uvod: Hepatička osteodistrofija je termin koji obuhvata metaboličke bolesti kosti udružene sa hroničnim bolestima jetre. U alkoholnoj cirozi (AC) jetre postoji visoka zastupljenost deficijencije vitamina D proporcionalna stepenu disfunkcije jetre, ali njena uloga u patogenezi hepatičke osteodistrofije nije dovoljno obja&scaron;njena. Nivo 25(OH)D odražava status vitamina D. Kod AC jetre izmenjena je metabolička aktivnost kosti i suprimirano je formiranje kosti &scaron;to dovodi do smanjenja ko&scaron;tane mase. U centru interesovanja je postizanje optimalnog statusa vitamina D. Stavovi o suple

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31

Mosavat, Maryam. "The role of sleep duration and quality in vitamin D metabolism and their association with glucose homeostasis in pregnancy." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2023. https://ro.ecu.edu.au/theses/2620.

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Pregnancy due to several factors may predispose women to insufficient and poor sleep quality. Sleep is an important regulator of body metabolism and energy homeostasis. Vitamin D, along with its classical action in mineral homeostasis plays an important role in metabolic regulation. Both sleep deprivation and vitamin D deficiency have been linked independently and separately to hyperglycemia and pathogenesis of type 2 diabetes. To date, the potential association between sleep, vitamin D level and glycemic level in pregnancy have received little attention. This study aimed to investigate the re

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Klumpp, Karoline [Verfasser]. "Interaktion zwischen verschiedenen Vitamin-D-Metaboliten und Mechanismen zur Metabolisierung und Elimination von Xenobiotika bei der RatteInteraction between different vitamin D metabolites and mechanisms for metabolism and elimination of xenobiotics in rats / Karoline Klumpp." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2018. http://d-nb.info/1177951436/34.

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33

Schnell, David M. "VITAMIN D WORKS THROUGH THE LIPID DROPLET PROTEIN PLIN2 TO AUGMENT MITOCHONDRIAL FUNCTION IN SKELETAL MUSCLE." UKnowledge, 2018. https://uknowledge.uky.edu/pharmacol_etds/23.

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Vitamin D has been connected with increased intramyocellular lipid (IMCL) mitochondrial function in skeletal muscle. It is also shown to prevent lipotoxicity in several tissues, but this has not yet been examined in skeletal muscle. Perilipin 2 (PLIN2), a lipid droplet protein upregulated with vitamin D treatment, is integral to managing IMCL capacity and lipid oxidation in skeletal muscle. Increased lipid storage and oxidation is associated with increased tolerance to a hyperlipidic environment and resistance to lipotoxicity. Therefore, I hypothesized that vitamin D increases β-oxidation and

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34

Leonard, Franciska. "Modulation of the intestinal vitamin D receptor and calcium ATPase activity by essential fatty acid supplementation." Diss., University of Pretoria, 1999. http://hdl.handle.net/2263/24269.

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35

Almokhtar, Mokhtar. "Expression and regulation of steroid metabolizing enzymes in cells of the nervous and skeletal systems : Special focus on vitamin D metabolism." Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-333920.

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Little is known about the mechanisms of vitamin D actions in the brain and bone. In this study, the metabolism of vitamin D and its regulation in various cell cultures of the nervous and skeletal systems were examined. Human osteosarcoma Saos-2 cells, human primary osteoblasts (hOB) and murine motor neuron-like NSC-34 cells were found to express mRNA for all enzymes required in vitamin D3 metabolism as well as the vitamin D receptor (VDR) that mediates vitamin D actions. Also, production of 24,25-dihydroxyvitamin D3 was found in these cells. Studies on vitamin D metabolism in NSC-34 cells and

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Harder, Jutta [Verfasser], da Costa Clarissa [Akademischer Betreuer] Prazeres, Bettina [Gutachter] Kuschel, and da Costa Clarissa [Gutachter] Prazeres. "Vitamin D receptor and its immunological role within the human placenta - Analysis of vitamin D metabolism and immunologically important genes at the feto-maternal interface / Jutta Harder ; Gutachter: Bettina Kuschel, Clarissa Prazeres da Costa ; Betreuer: Clarissa Prazeres da Costa." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1203799446/34.

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Dollin, Kiera. "Influence of genetics and diet on the regulation of vitamin D metabolism in the elderly and its contribution to age-related macular degeneration." Thesis, Queen's University Belfast, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579709.

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Age-related macular degeneration (AMD) is the leading cause of severe visual impairment and blindness in the developed world. The exact pathogenesis of AMD is unknown, however, in common with cardiovascular disease, AMD may be underpinned by chronic inflammatory processes which lead to prolonged activation of both resident and recruited macrophage-like microglial (MG) cells. Vitamin D is a prohormone which can be produced in the skin following exposure to UVB radiation. It can also be obtained from dietary sources such as oily fish and from supplements. The main circulating metabolite, 25-hydr

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Salem, Hassan [Verfasser], Rolf G. [Akademischer Betreuer] Beutel, Martin [Akademischer Betreuer] Kaltenpoth, and Heike [Akademischer Betreuer] Feldhaar. "Actinobacteria and the vitamin metabolism of firebugs : characterizing a mutualisms specificity and functional importance / Hassan Salem. Gutachter: Rolf Georg Beutel ; Martin Kaltenpoth ; Heike Feldhaar." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2015. http://d-nb.info/1066238324/34.

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Mason, Shelley S. "Exploring Tissue Engineering: Vitamin D3 Influences on the Proliferation and Differentiation of an Engineered Osteoblast Precursor Cell Line During Early Bone Tissue Development." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/1000.

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Most of the load-bearing demand placed on the human body is transduced by skeletal tissue, and the capacity of the skeleton to articulate in various opposing directions is essential for body movement and locomotion. Consequently, cartilage and bone defects due to trauma, disease, and developmental abnormalities result in disabling pain and immobility for millions of people worldwide. A novel way of promoting cartilage and bone regeneration is through the incorporation of either primary cells or multipotent progenitor cells in a three-dimensional (3D) biomaterial scaffold, and/or the addition o

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Sobeck, Ulrike [Verfasser]. "Interference of Benzo(a)pyrene in the Metabolism of Vitamin A in Human Bronchial Epithelial Cells : Uptake of Topically Applied Vitamin A in Buccal Mucosal Cells - A Pilot Study and a Randomised, Placebo Controlled, and Double Blind Trial / Ulrike Sobeck." Aachen : Shaker, 2003. http://d-nb.info/1170540619/34.

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Schuch, Natielen Jacques. "Relação entre as concentrações séricas da vitamina D, polimorfismos do gene do VDR e síndrome metabólica em adultos e idosos." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-20012012-093621/.

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Introdução - O receptor de vitamina D (VDR) é expresso em vários tecidos e quando este se encontra na sua forma ativada, modula a expressão de diversos genes. Esses incluem variações dos níveis circulantes de 1,25(OH) 2 D , variações na densidade mineral óssea, secreção e sensibilidade à insulina em resposta à glicose, suscetibilidade à diabetes tipo 1 e 2, obesidade, dislipidemias e hipertensão arterial. Atualmente, evidências têm sugerido o envolvimento da vitamina D com a síndrome metabólica. Objetivo - Investigar a concentração sérica da vitamina D e sua relação com a síndrome metabólica e

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Schubert, Martin [Verfasser], Marc [Gutachter] Birringer, Michael Marcus [Gutachter] Hoffmann, and Stefan [Gutachter] Lorkowski. "At the crossroads of inflammation and lipid metabolism : modulation of macrophage functionality by long-chain metabolites of Vitamin E and related compounds / Martin Schubert ; Gutachter: Marc Birringer, Michael Marcus Hoffmann, Stefan Lorkowski." Jena : Friedrich-Schiller-Universität Jena, 2021. http://d-nb.info/124030952X/34.

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Schmitt, Eneida Maria Boteon [UNESP]. "Associação entre a deficiência de vitamina D e os marcadores da síndrome metabólica em mulheres na pós-menopausa." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/150309.

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Weber, Susanne [Verfasser], Jerzy [Akademischer Betreuer] [Gutachter] Adamski, Michael [Gutachter] Rychlik, and Johannes [Gutachter] Buchner. "Characterization of the novel human aldo-keto reductase AKR1B15 and the 17beta-hydroxysteroid dehydrogenase 17beta-HSD12 and analysis of vitamin D metabolism in cells / Susanne Weber ; Gutachter: Michael Rychlik, Jerzy Adamski, Johannes Buchner ; Betreuer: Jerzy Adamski." München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1147565732/34.

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Schmitt, Eneida Maria Boteon. "Associação entre a deficiência de vitamina D e os marcadores da síndrome metabólica em mulheres na pós-menopausa." Botucatu, 2017. http://hdl.handle.net/11449/150309.

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Orientador: Eliana Aguiar Petri Nahas<br>Resumo: Objetivo: avaliar a associação entre deficiência de vitamina D e os marcadores de risco para síndrome metabólica (SM) em mulheres na pós-menopausa. Métodos: Realizou-se estudo clínico de corte transversal com 466 mulheres, idade entre 45-75 anos, atendidas em Hospital Universitário. Foram incluídas mulheres em amenorréia >12 meses e idade ≥ 45 anos, sem uso de medicações ou condições clínicas que interfiram nos valores da vitamina D e sem doença cardiovascular estabelecida. Foram coletados dados clínicos, antropométricos e laboratoriais [coleste

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Genaro, Patricia de Souza. "Consumo alimentar e metabolismo mineral e ósseo em mulheres idosas com sarcopenia." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/6/6133/tde-24052010-095200/.

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Introdução a redução da massa muscular esquelética relacionada à idade, denominada sarcopenia, está associada com maior incidência de quedas, fraturas e dependência funcional em idosos. Muitos são os fatores que podem contribuir para o surgimento da sarcopenia, dentre eles a deficiência de vitamina D e a inadequação do consumo alimentar, principalmente a ingestão de proteína. Objetivos investigar a relação da sarcopenia com o consumo alimentar e concentração sérica de 25(OH)D. Métodos Foram avaliadas 200 mulheres acima de 65 anos, sendo 35 com sarcopenia e 165 sem sarcopenia. Avaliou-se a d

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von, Hurst Pamela Ruth. "The role of vitamin D in metabolism and bone health : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Nutritional Science at Massey University, Albany, New Zealand." Massey University, 2009. http://hdl.handle.net/10179/1148.

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Background Hypovitaminosis D is becoming recognised as an emerging threat to health, even in countries like New Zealand which enjoy plentiful sunshine. The evidence for a role for vitamin D deficiency in the aetiology of a plethora of diseases continues to accumulate, including type 2 diabetes, and the preceding insulin resistance. Objectives The primary objective of the Surya Study was to investigate the effect of improved vitamin D status (through supplementation) on insulin resistance. The secondary objectives were to investigate the vitamin D status and bone mineral density of South Asi

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BRASME, HAUTECOEUR ANNIE. "Metabolisme et indications therapeutiques de la vitamine d et de ses derives." Lille 2, 1997. http://www.theses.fr/1997LIL2P031.

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Torremadé, Pascual Noèlia. "Efecte de la urèmia en el metabolisme de la vitamina D: implicacions en la calcificació vascular." Doctoral thesis, Universitat de Lleida, 2013. http://hdl.handle.net/10803/131162.

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La calcificació vascular és una complicació de la malaltia renal crònica i una de les principals causes de l’augment de morbiditat i mortalitat en els pacients. Aquests pacients presenten una disminució en els nivells de vitamina D (1,25(OH)2D3) i desenvolupen hiperparatiroïdisme secundari. Per aquest motiu, pacients amb MRC són tractats amb calcitriol o altres anàlegs. La 25-hidroxivitaminaD també s'utilitza, però sense cap coneixement de la seva eficàcia i toxicitat. Les recomanacions actuals indiquen que s’ha de suplementar amb 25D per assolir un llindar determinat que pugui afectar les acc

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FERHAT, FARID. "Interaction entre le diabete et le metabolisme du calciferol." Strasbourg 1, 1987. http://www.theses.fr/1987STR10688.

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