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Journal articles on the topic 'Vitamin E supplementation'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

McDowell, L. R. "Vitamin nutrition of livestock animals: Overview from vitamin discovery to today." Canadian Journal of Animal Science 86, no. 2 (2006): 171–79. http://dx.doi.org/10.4141/a05-057.

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The term “vitamin” or “vitamine” was first used in 1912. What later became known as vitamin deficiency diseases — scurvy, beriberi, night blindness and xeropthalmia — had plagued the world from antiquity. From 1900 through the 1930s, experiments with animals helped to advance knowledge of vitamins considerably. There are 15 vitamins of significance for livestock. A number of factors influence vitamin requirements and vitamin utilization, including physiological make-up and production function; confinement rearing without pasture; stress, disease and adverse environmental conditions; vitamin an

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Garcia, Fabiana, Fabiana Pilarski, Eduardo Makoto Onaka, and Flávio Ruas de Moraes. "Performance and hematology of pacu fed diets supplemented with vitamins C and/or E." Scientia Agricola 68, no. 3 (2011): 314–19. http://dx.doi.org/10.1590/s0103-90162011000300007.

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Pacu (Piaractus mesopotamicus Holmberg, 1887) is a valued Brazilian fish species for aquaculture. This is highly susceptible to disease, and feed supplementations for pacu can be a very important strategy to prevent disease incidence in fish farms. The aim of this study was to evaluate a strategic supplementation for pacu. Juvenile pacu (10.5 ± 1.2 g) were fed diets containing three levels of vitamins C and/or E (0, 250, and 500 mg vitamin kg-1 diet). Fish were fed diets without supplementation for two months prior to the experiment. After that period, experimental feeding was initiated for tw

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3

Serra-Majem, Lluís, Rosa Ortega, Javier Aranceta, Alfredo Entrala, and Angel Gil. "Fortified foods. Criteria for vitamin supplementation in Spain." Public Health Nutrition 4, no. 6a (2001): 1331–34. http://dx.doi.org/10.1079/phn2001211.

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AbstractObjective:To review and analyse criteria for vitamin supplementation and fortification in Spain.Design:Systematic review of scientific literature and simulation analysis of food fortification.Methods:A simulation analysis using a fortified beverage was performed in a random sample of 2855 children aged 2 to 24 years in Spain.Results:High-risk groups for vitamin supplementation and fortification in Spain are highlighted, and target vitamins considered have been: folic acid, vitamin A, vitamin E, vitamin D and vitamin B12 (particularly in the elderly). A beverage fortified with vitamins

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Fishman, Steven M., Parul Christian, and Keith P. West. "The role of vitamins in the prevention and control of anaemia." Public Health Nutrition 3, no. 2 (2000): 125–50. http://dx.doi.org/10.1017/s1368980000000173.

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AbstractObjectiveWhile iron deficiency is regarded as the major cause of nutritional anaemia, changes in vitamins A, B12, C and E, folic acid and riboflavin status have also been linked to its development and control. This paper provides a systematic review of vitamin supplementation trials relating to the control of nutritional anaemia.MethodsA MEDLINE search was used to find reports of vitamin supplementation trials that reported changes in anaemia or iron status.ResultsVitamin A can improve haematological indicators and enhance the efficacy of iron supplementation. Both folate and vitamin B

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Badkook, Maha, Fiona McCullough, and Nessar Ahmed. "Effect of a high monounsaturated fatty acid diet alone or with combined vitamin E and C, or lycopene intake on oxidative stress in patients with type 2 diabetes mellitus." British Journal of Diabetes & Vascular Disease 12, no. 2 (2012): 81–86. http://dx.doi.org/10.1177/1474651412442094.

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The aims of this study were to investigate the effect of a high monounsaturated fatty acid (MUFA) diet alone or with combined vitamin E and C, or lycopene intake on oxidative stress in type 2 diabetes in Saudi Arabia. Forty-eight type 2 diabetic patients consumed a high MUFA diet for 16 weeks. After four weeks of high MUFA diet alone, supplements of vitamins E (400 mg) and C (1,000 mg) were taken for four weeks, followed by a four-week washout period. In the final four weeks, subjects consumed a high MUFA diet with tomato paste (equivalent to 12 mg lycopene). Plasma samples were tested for vit

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van Ballegooijen, Adriana J., Stefan Pilz, Andreas Tomaschitz, Martin R. Grübler, and Nicolas Verheyen. "The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review." International Journal of Endocrinology 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/7454376.

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Vitamins D and K are both fat-soluble vitamins and play a central role in calcium metabolism. Vitamin D promotes the production of vitamin K-dependent proteins, which require vitamin K for carboxylation in order to function properly. The purpose of this review is to summarize available evidence of the synergistic interplay between vitamins D and K on bone and cardiovascular health. Animal and human studies suggest that optimal concentrations of both vitamin D and vitamin K are beneficial for bone and cardiovascular health as supported by genetic, molecular, cellular, and human studies. Most cl

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Fogagnolo, Paolo, Stefano De Cilla’, Micol Alkabes, Pierfilippo Sabella, and Luca Rossetti. "A Review of Topical and Systemic Vitamin Supplementation in Ocular Surface Diseases." Nutrients 13, no. 6 (2021): 1998. http://dx.doi.org/10.3390/nu13061998.

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In the homeostasis of the ocular surface, vitamins play a critical role in regulating inflammatory responses and promoting cell differentiation, development and correct function. Systemic vitamin supplementation has been available for many decades; in recent years, thanks to pharmacological advancements, topical vitamin delivery has also become available in an attempt to better treat ocular surface disease (OSD) and dry eye disease (DED). In this paper, we reviewed the current evidence on the role of vitamin supplementation in OSD and DED. We originally searched the PubMed archive, inspected t

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Turner, Eleanor. "P045 Value from your vitamins – optimising vitamin supplementation in children with cystic fibrosis." Archives of Disease in Childhood 104, no. 7 (2019): e2.50-e2. http://dx.doi.org/10.1136/archdischild-2019-nppc.54.

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AimTo optimise fat soluble vitamin supplementation in children with CF in a tertiary children’s hospital and primary care. To compare supplementation of individual vitamins and supplementation with a new multivitamin preparation against national guidelines, cost and patient acceptability.1MethodsComparison of current practice (supplementation of individual vitamins) with a new multi-vitamin preparation, Paravit-CF. Form and dose of each of the fat soluble vitamins was compared against national CF Trust guidelines for nutrition.1 Cost of treatment per day was compared. Patient acceptability was

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9

Li, Mengyan, Ruodi Ren, Kunkun Wang, et al. "Effects of B Vitamins on Homocysteine Lowering and Thrombotic Risk Reduction—A Review of Randomized Controlled Trials Published Since January 1996." Nutrients 17, no. 7 (2025): 1122. https://doi.org/10.3390/nu17071122.

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Homocysteine is an amino acid derived from methionine which is metabolized via vitamin B6 (pyridoxine)- and vitamin B12 (cobalamin)-dependent pathways. Supplementation of B vitamins has been shown to effectively reduce plasma homocysteine levels. Previous research has also demonstrated an association between lower plasma homocysteine levels and decreased risk of myocardial infarction, stroke, and venous thromboembolism. However, whether supplementation of B vitamins is associated with risk reduction in thromboembolic events and confers clinical benefits remains inconclusive. This review examin

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Hinson, Rodney, Katherine McCormick, Ronny Moser, Matthew Ackerman, Rodger Main, and Julie Mahoney. "Reduced vitamin supplementation with fat-soluble vitamins A, D, and E added at National Research Council requirements may not be adequate for optimal sow and progeny performance." Journal of Swine Health and Production 30, no. 2 (2022): 79–94. http://dx.doi.org/10.54846/jshap/1259.

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Objective: To evaluate performance and physiological vitamin status of sows and progeny fed 2 vitamin supplementation levels, industry vs reduced (all vitamins reduced with fat-soluble vitamins added at National Research Council recommendations). Materials and methods: Sows (n = 244) were allotted in a randomized complete block design to 1 of 2 vitamin supplementation levels. At weaning, 765 progeny from a subset of sows were allotted to treatments in a 2 × 2 factorial arrangement of two sow and two nursery vitamin supplementation levels with 15 pens/treatment. Performance and vitamin status o

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Siener, Roswitha, Ihsan Machaka, Birgit Alteheld, Norman Bitterlich, and Christine Metzner. "Effect of Fat-Soluble Vitamins A, D, E and K on Vitamin Status and Metabolic Profile in Patients with Fat Malabsorption with and without Urolithiasis." Nutrients 12, no. 10 (2020): 3110. http://dx.doi.org/10.3390/nu12103110.

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Patients with intestinal fat malabsorption and urolithiasis are particularly at risk of acquiring fat-soluble vitamin deficiencies. The aim of the study was to evaluate the vitamin status and metabolic profile before and after the supplementation of fat-soluble vitamins A, D, E and K (ADEK) in 51 patients with fat malabsorption due to different intestinal diseases both with and without urolithiasis. Anthropometric, clinical, blood and 24-h urinary parameters and dietary intake were assessed at baseline and after ADEK supplementation for two weeks. At baseline, serum aspartate aminotransferase

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Jose, Rosmi, Venketeswaramurthy N, and Sambath Kumar R. "A CRITICAL REVIEW ON HYPOTHESIS, PATHOPHYSIOLOGY OF SCHIZOPHRENIA, AND ROLE OF VITAMINS IN ITS MANAGEMENT." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 25. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.23259.

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This review describes about the literatures addressing the role of vitamin supplementation in schizophrenia. Evidence is suggesting that vitamin supplementation includes Vitamin A, Vitamin D, Vitamin E, Vitamin B complex, and Vitamin C may be important in treatment. In schizophrenia, patients may have increased level of homocysteine (Hcy), due to the polymorphism in methylenetetrahydrofolate reductase and hypofunction of N-methyl-D-aspartate receptors. The vitamins main effects are reduced the Hcy level and maintain dopamine and serotonin levels. Add-on treatment with high-dose B vitamins incl

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Sharma, Nalini, Bradley Trope, and Timothy O. Lipman. "Vitamin Supplementation." Journal of Clinical Gastroenterology 38, no. 10 (2004): 844–54. http://dx.doi.org/10.1097/00004836-200411000-00003.

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Persson, P. B., and A. B. Persson. "Vitamin supplementation." Acta Physiologica 219, no. 3 (2017): 539–41. http://dx.doi.org/10.1111/apha.12850.

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Nguyen, Yann, Johanna Sigaux, Jean-Guillaume Letarouilly, et al. "Efficacy of Oral Vitamin Supplementation in Inflammatory Rheumatic Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Nutrients 13, no. 1 (2020): 107. http://dx.doi.org/10.3390/nu13010107.

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Background: We aimed to provide a systematic review and meta-analysis of randomized controlled trials assessing the effect of oral vitamin supplementation on symptoms and disease activity in patients with rheumatoid arthritis (RA), spondyloarthritis (SpA) and psoriatic arthritis (PsA). Methods: A systematic literature review and meta-analysis of randomized controlled trials including patients with inflammatory rheumatic diseases were performed using MEDLINE, EMBASE and abstracts from recent international rheumatology congresses. Studies were reviewed in accordance with PRISMA guidelines. We an

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Dr. Lokesh. K, Dr Lokesh K., Dr Borus Purushothaman, Dr Yashmi Agwina Xavier, Veerammal Veerammal, and Dr Suman Sharma. "Impact of Vitamin A and Vitamin D3 in sperm morphology." International Journal of Pharmaceutical Research and Applications 09, no. 05 (2024): 840–48. https://doi.org/10.35629/4494-0905840848.

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Vitamins A and D3 play essential roles in various physiological processes, including reproductive health. This study investigates the effects of Vitamin A and Vitamin D3 supplementation on sperm morphology in male subjects. The experimental design included a control group and two test groups, one receiving Vitamin A and the other Vitamin D3, over a 12-week period. Sperm samples were collected pre- and postsupplementation and analyzed for morphological changes using standardized criteria. Results indicate that both vitamins significantly improve sperm morphology, though through different mechan

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Sivagurunathan, U., David Dominguez, Yiyen Tseng, María Jesús Zamorano, Antony Jesu Prabhu Philip, and Marisol Izquierdo. "Interaction between Dietary Vitamin D3 and Vitamin K3 in Gilthead Seabream Larvae (Sparus aurata) in Relation to Growth and Expression of Bone Development-Related Genes." Aquaculture Nutrition 2023 (May 23, 2023): 1–21. http://dx.doi.org/10.1155/2023/3061649.

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Vitamins D and K are essential fat-soluble nutrients that intervene in bone development processes among other biological functions. The present study is aimed at investigating the potential combined effect of dietary supplementation with vitamin D3 (cholecalciferol) and vitamin K3 (menadione) in gilthead seabream (Sparus aurata) larvae. For that purpose, seabream diets were supplemented with different combinations of vitamin D3/vitamin K3 (mg/kg diet) as follows: 0.00/0, 0.06/70, 0.06/170, 0.13/70, 0.13/170, 0.40/70, and 0.40/170. Feeding gilthead seabream larvae (22 days post hatch) for 21 da

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Saastamoinen, Markku, and Johanna Juusela. "Influence of dietary supplementation on serum vitamin A and D concentrations and their seasonal variation in horses." Agricultural and Food Science 1, no. 5 (1992): 477–82. http://dx.doi.org/10.23986/afsci.72460.

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An experiment involving 40 adult trotters and saddle horses was conducted during a period of one year in order to investigate the influence of vitamin A (retinol) and D (25-(OH)D) supplementation on serum vitamin concentrations and the seasonal variation of the serum concentrations of these vitamins. Vitamin supplementation was started either at the beginning or in the middle of the indoor (winter) feeding period. Supplementation lasted from the beginning of September or January to the end of May. According to the results, neither the dietary vitamin supplementation nor the length of the grazi

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Ashor, Ammar W., Mario Siervo, Jose Lara, Clio Oggioni, Sorena Afshar, and John C. Mathers. "Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials." British Journal of Nutrition 113, no. 8 (2015): 1182–94. http://dx.doi.org/10.1017/s0007114515000227.

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Randomised controlled trials (RCT) testing the effects of antioxidant supplements on endothelial function (EF) have reported conflicting results. We aimed to investigate the effects of supplementation with antioxidant vitamins C and E on EF and to explore factors that may provide explanations for the inconsistent results. We searched four databases (MEDLINE, Embase, Cochrane Library and Scopus) from inception until May 2014 for RCT involving adult participants aged ≥ 18 years who were supplemented with vitamins C and E alone or in combination for more than 2 weeks and reporting changes in EF m

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Haymes, Emily M. "Vitamin and Mineral Supplementation to Athletes." International Journal of Sport Nutrition 1, no. 2 (1991): 146–69. http://dx.doi.org/10.1123/ijsn.1.2.146.

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Vitamin and mineral supplements are frequently used by competitive and recreational athletes. Dietary deficiencies of most vitamins are not very common among athletes except in those who restrict their food intake in order to maintain body weight. Vitamins most likely to be deficient in the diet are folate,,, and E. Biochemical evidence of vitamin deficiencies in some athletes have been reported for thiamine, riboflavin, and. When the diet is deficient, vitamin supplements may improve performance but are not likely to be effective if the dietary intake is adequate. Some female athletes' diets

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Angelopoulos, Nikolaos, Rodis D. Paparodis, Ioannis Androulakis, Anastasios Boniakos, and Sarantis Livadas. "Effects of a Novel Dispersible Supplement Containing 2500 IU of Vitamin D and 1000 µg of B12 in Restoring Vitamin D and B12 Insufficiency: A Multicenter, Randomized Controlled Trial." Nutrients 17, no. 3 (2025): 419. https://doi.org/10.3390/nu17030419.

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Background/Objectives: Vitamins D and B12 play a crucial role in maintaining bone health, immune function, and neurological integrity. Combined deficiencies in these vitamins can lead to severe health consequences. Current treatment approaches, such as dietary changes and single-vitamin supplementation, often fail to address these deficiencies comprehensively. This study evaluates the effectiveness of concurrent vitamin D and B12 supplementation to correct these insufficiencies. Methods: A prospective, multicenter, randomized controlled trial was conducted in Greece from October 2024 to Decemb

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Juszczak, Aleksandra Beata, Maciej Kupczak, and Tomasz Konecki. "Does Vitamin Supplementation Play a Role in Chronic Kidney Disease?" Nutrients 15, no. 13 (2023): 2847. http://dx.doi.org/10.3390/nu15132847.

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Although the role of vitamins in the human body is proven, guidelines for patients with chronic kidney disease (CKD) remain unclear. This narrative review summarizes the findings of 98 studies of CKD and the effects of vitamin D, B, C, A, E, and K supplementation on patients on dialysis for CKD, with the aim of summarizing the existing guidelines. The findings are promising, showing the potential effectiveness of vitamin supplementation with, for example, vitamins B, D, or C. However, recommendations are still ambiguous, especially in the case of vitamins A and K, due to the potential toxicity

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Karamali, Maryam, Mahnaz Ashrafi, Maryamalsadat Razavi, Mehri Jamilian, Maryam Akbari, and Zatollah Asemi. "The Effects of Calcium, Vitamins D and K co-Supplementation on Markers of Insulin Metabolism and Lipid Profiles in Vitamin D-Deficient Women with Polycystic Ovary Syndrome." Experimental and Clinical Endocrinology & Diabetes 125, no. 05 (2017): 316–21. http://dx.doi.org/10.1055/s-0043-104530.

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Abstract Data on the effects of calcium, vitamins D and K co-supplementation on markers of insulin metabolism and lipid profiles among vitamin D-deficient women with polycystic ovary syndrome (PCOS) are scarce. This study was done to determine the effects of calcium, vitamins D and K co-supplementation on markers of insulin metabolism and lipid profiles in vitamin D-deficient women with PCOS. This randomized double-blind, placebo-controlled trial was conducted among 55 vitamin D-deficient women diagnosed with PCOS aged 18–40 years old. Subjects were randomly assigned into 2 groups to intake ei

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Chrysostomou, Stavri. "Vitamin D Daily short-term Supplementation does not Affect Glycemic Outcomes of Patients with Type 2 Diabetes." International Journal for Vitamin and Nutrition Research 86, no. 5-6 (2016): 169–83. http://dx.doi.org/10.1024/0300-9831/a000239.

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There is currently insufficient evidence of a beneficial effect to recommend vitamin D supplementation for optimizing glycemic status in patients with type 2 diabetes mellitus (T2DM). Taking into consideration the significant extra-skeletal effect of vitamin D on pancreatic β-cell function and insulin secretion and the large number of scientific evidence supporting the inverse association between vitamin D status and hyperglycemia, this review article aims to examine whether vitamin D supplementation therapies are beneficial to patients with T2DM considering specific factors through randomized

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Galan, Pilar, Serge Briançon, Alain Favier, et al. "Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels?" British Journal of Nutrition 94, no. 1 (2005): 125–32. http://dx.doi.org/10.1079/bjn20051462.

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The SUpplementation en VItamines et Mineraux AntioXydants (SU.VI.MAX) study, a randomised double-blind, primary-prevention trial showed that after 7·5 years, low-dose antioxidant supplementation lowered the total cancer incidence in men, but not in women. To explain this difference in the impact of antioxidant supplementation in men and women, we hypothesised that the effect of supplementation is dependent on initial antioxidant status; 12 741 French adults (7713 females aged 35–60 years; 5028 males aged 45–60 years) received daily antioxidant supplementation (120 mg vitamin C, 30 mg vitamin E

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Biłogras, Jan, Kornelia Karamus, Rafał Rejmak, et al. "Effect of vitamin D supplementation." Journal of Education, Health and Sport 76 (December 8, 2024): 56537. https://doi.org/10.12775/jehs.2024.76.56537.

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Introduction Vitamin D is one of the most important vitamins in affecting the human body. It turns out that its influence is not limited to its health-promoting effect on the skeletal system, but may also play an important role in the immune system. In our study, we focused precisely on this aspect of vitamin D's action. Review method We used materials from PubMed for this purpose. We focused on articles and research papers published between 2019 and 2024. We reviewed the publications in terms of vitamin D supplementation and its effects on immunity, disease processes, patient recovery, COVID-

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Flohr, Josh, Joel DeRouchey, Jason Woodworth, Mike Tokach, Robert Goodband, and Steve Dritz. "A survey of current feeding regimens for vitamins and trace minerals in the US swine industry." Journal of Swine Health and Production 24, no. 06 (2016): 290–303. http://dx.doi.org/10.54846/jshap/963.

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Objective: To describe added vitamin and trace-mineral concentrations used in the US swine industry for breeding and growing pigs. Materials and methods: A convenience sample survey of nutritionists from 18 US swine production systems representing approximately 2.3 million sows or 40% of the US sow herd was conducted to characterize added vitamin and trace-mineral concentrations in swine diets. Data were compiled by dietary phases to determine descriptive statistics. Nutrients evaluated were vitamins A, D, E, and K; biotin; choline; folic acid; niacin; pantothenic acid; pyridoxine; riboflavin;

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Kim, Mi Kyung, Satoshi Sasaki, Shizuka Sasazuki, Shunji Okubo, Masato Hayashi, and Shoichiro Tsugane. "Long-term vitamin C supplementation has no markedly favourable effect on serum lipids in middle-aged Japanese subjects." British Journal of Nutrition 91, no. 1 (2004): 81–90. http://dx.doi.org/10.1079/bjn20031024.

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Antioxidant vitamins have been reported to be associated with an improvement in blood lipid profiles, but results are not consistent. The present study was designed to determine whether long-term vitamin C supplementation could alter serum lipid concentrations in subjects who completed a 5-year population-based double-blind intervention trial. A total of 439 Japanese subjects with atrophic gastritis initially participated in the trial using vitamin C and β-carotene to prevent gastric cancer. Before and upon early termination of β-carotene supplementation, 134 subjects dropped out of the trial;

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Lee, Anthony W., Gale L. Romanowski, James A. Proudfoot, and Dennis J. Kuo. "Effect of Vitamin D Supplementation on Delayed Hyperphosphatemia in Pediatric Acute Lymphoblastic Leukemia Patients During Induction Chemotherapy." Journal of Pediatric Pharmacology and Therapeutics 22, no. 2 (2017): 102–5. http://dx.doi.org/10.5863/1551-6776-22.2.102.

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OBJECTIVES Vitamin D plays a role in maintaining bone health and calcium metabolism, but recent studies cast doubt on vitamin D supplementation's benefits in survivors of acute lymphoblastic leukemia (ALL). Vitamin D supplementation could increase serum phosphate through increased intestinal absorption of phosphate and suppression of parathyroid hormone, which would lead to decreased renal phosphate excretion. Because of the potential for renal injury during induction chemotherapy for ALL, Vitamin D supplementation's potential for increasing hyperphosphatemia could outweigh its suggested but u

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Parraguez, Víctor H., Miljenko Atlagich, Oscar Araneda, et al. "Effects of antioxidant vitamins on newborn and placental traits in gestations at high altitude: comparative study in high and low altitude native sheep." Reproduction, Fertility and Development 23, no. 2 (2011): 285. http://dx.doi.org/10.1071/rd10016.

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The present study evaluated the hypothesis that the effects of hypoxia on sheep pregnancies at high altitude (HA) are mediated by oxidative stress and that antioxidant vitamins may prevent these effects. Both HA native and newcomer ewes were maintained at an altitude of 3589 m during mating and pregnancy. Control low altitude (LA) native ewes were maintained at sea level. Half of each group received daily oral supplements of vitamins C (500 mg) and E (350 IU) during mating and gestation. Near term, maternal plasma vitamin levels and oxidative stress biomarkers were measured. At delivery, lambs

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Asbaghi, Omid, Mohammad Khosroshahi, Sara Kashkooli, and Amir Abbasnezhad. "Effect of Calcium‑Vitamin D Co‑Supplementation on Insulin, Insulin Sensitivity, and Glycemia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials." Hormone and Metabolic Research 51, no. 05 (2019): 288–95. http://dx.doi.org/10.1055/a-0887-0205.

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AbstractWe conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the effect of calcium-vitamin D co‑supplementation on insulin, insulin sensitivity, and glycemia. A systematic search was carried out in Web of Science, PubMed, EMBASE, Scopus, and Cochrane library without any language and time restriction up to 12 August 2018, to retrieve the RCTs, which examined the effect of calcium and vitamin D co-supplementation on fasting blood glucose (FBG), insulin, HOMA-B, HOMA-IR, and QUICKI. Meta-analyses were carried out using a random effects model, and I2

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Brönstrup, Hages, and Pietrzik. "Lowering of Homocysteine Concentrations in Elderly Men and Women." International Journal for Vitamin and Nutrition Research 69, no. 3 (1999): 187–93. http://dx.doi.org/10.1024/0300-9831.69.3.187.

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B-vitamin supplementation has previously been shown to lower the concentration of plasma total homocysteine, a risk factor for cardiovascular disease. Little is known about the homocysteine-lowering effects of low-dose B-vitamins in elderly individuals, who are prone to higher homocysteine levels due to advanced age and a greater frequency of impaired vitamin status. We aimed to identify if and to what extent B-vitamins lower total homocysteine and its subfractions in elderly individuals. Men and women (>= 60 years) received either B-vitamins (400 mug folic acid +1.65 mg pyridoxine +3 mug c

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Marques, Rafael Henrique, Rodrigo Antonio Gravena, Janaina Della Torre da Silva, et al. "Effect of supplementation of diets for quails with vitamins A, D and E on performance of the birds and quality and enrichment of eggs." Revista Brasileira de Zootecnia 40, no. 6 (2011): 1222–32. http://dx.doi.org/10.1590/s1516-35982011000600010.

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The objective of this research was to evaluate the performance of birds and the quality and enrichment of eggs from quails fed diets supplemented with vitamins A, D and E. Three experiments were performed, one for each vitamin, under completely randomized experimental design, with six replicates and eight birds per plot, totaling 192 quails. Performance of birds was evaluated by the daily feed intake, egg weight, laying percentage (%) and food conversion, per kg and dozen of eggs. It was also evaluated the internal quality (Haugh unit, yolk index and yolk and albumen percentages) and external

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Coelho, Michael, Robert Jones, and Frank Parks. "PSVII-1 The effect of supplementing pigs with the BASF annual industry vitamin supplementation on performance." Journal of Animal Science 97, Supplement_2 (2019): 215–16. http://dx.doi.org/10.1093/jas/skz122.379.

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Abstract There is a continued industry focus to decrease FCR (Pierozan, 2016), which means less feed per kg body tissue, and therefore vitamins need to be further concentrated in less and less feed to reach the same vitamin supplementation per kg of body tissue. A study was conducted to determine the response of pigs to different levels of vitamin supplementation based on the 2018 BASF Industry vitamin supplementation survey. Pigs were stressed to simulate commercial stress conditions. A total of 240 (PIC 337 x Camborough) pigs were used in a randomized complete block design with pen as the ex

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Mozos, Ioana, Dana Stoian, and Constantin Tudor Luca. "Crosstalk between Vitamins A, B12, D, K, C, and E Status and Arterial Stiffness." Disease Markers 2017 (2017): 1–14. http://dx.doi.org/10.1155/2017/8784971.

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Arterial stiffness is associated with cardiovascular risk, morbidity, and mortality. The present paper reviews the main vitamins related to arterial stiffness and enabling destiffening, their mechanisms of action, providing a brief description of the latest studies in the area, and their implications for primary cardiovascular prevention, clinical practice, and therapy. Despite inconsistent evidence for destiffening induced by vitamin supplementation in several randomized clinical trials, positive results were obtained in specific populations. The main mechanisms are related to antiatherogenic

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Knez, Wade L., and Jonathan M. Peake. "The Prevalence of Vitamin Supplementation in Ultraendurance Triathletes." International Journal of Sport Nutrition and Exercise Metabolism 20, no. 6 (2010): 507–14. http://dx.doi.org/10.1123/ijsnem.20.6.507.

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Ultraendurance exercise training places large energy demands on athletes and causes a high turnover of vitamins through sweat losses, metabolism, and the musculoskeletal repair process. Ultraendurance athletes may not consume sufficient quantities or quality of food in their diet to meet these needs. Consequently, they may use oral vitamin and mineral supplements to maintain their health and performance. We assessed the vitamin and mineral intake of ultraendurance athletes in their regular diet, in addition to oral vitamin and mineral supplements. Thirty-seven ultraendurance triathletes (24 me

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Libonati, Giacinto Asprella, Antonello Leone, Salvatore Martellucci, et al. "Prevention of Recurrent Benign Paroxysmal Positional Vertigo: The Role of Combined Supplementation with Vitamin D and Antioxidants." Audiology Research 12, no. 4 (2022): 445–56. http://dx.doi.org/10.3390/audiolres12040045.

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Benign paroxysmal positional vertigo (BPPV) usually has a favorable course, although it is possible to observe BPPV with a high recurrence rate. Previous studies suggested that vitamin D deficiency might affect BPPV recurrences, and oxidative stress might play a complementary role in BPPV pathogenesis. This multicentric trial aimed to evaluate the effectiveness of oral nutritional supplementation with a compound of alpha-lipoic acid, Carnosine, and Zinc (LICA® (Difass International, Coriano (RN), Italy)), vitamins of group B and vitamin D in preventing BPPV recurrences. A total of 128 patients

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BEURA, T. K., N. PANDA, P. K. MISHRA, R. C. PATRA, P. C. BEHERA, and B. PANIGRAHI. "Effect of vitamin E and C supplementation on growth and antioxidant status of coloured chicken under hot and humid climatic stress." Indian Journal of Animal Sciences 82, no. 10 (2012): 1174–78. http://dx.doi.org/10.56093/ijans.v82i10.24292.

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The effect of vitamin E and/or vitamin C supplementation on growth and antioxidant status of coloured broiler chicks during summer stress was studied. Coloured broiler chicks (540) were divided into 9 treatment groups and were fed basal diet with supplementation of vitamin E (250 mg or 500 mg) and vitamin C (250 mg or 500 mg) either alone or in combinations from 0–56 days of age. The average weekly highest temperature and relative humidity during the experimental period was 37.98°C and 87.9% respectively. The growth rate, serum total antioxidant activity (TAA), anti oxidant enzymes i.e catalas

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Kalem, Müberra Namli, Zeynep Kamalak, Nermin Kosus, Aydin Kosus, and Ziya Kalem. "Prenatal multivitamin supplementation increases birth weight." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 6 (2017): 2148. http://dx.doi.org/10.18203/2320-1770.ijrcog20172305.

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Background: The aim of this study is to examine whether there is any positive impact of prenatal iron and vitamin supplementation on birth weight, and if this practice could be a cause of macrosomia.Methods: A total of 1,838 term pregnant women were included in this study and were divided into four groups: iron group (women having only iron supplementation), vitamin (women using only multivitamins), vitamin+iron (women using both iron and multivitamin preparations), and control group (women having neither iron nor vitamin supplements). Statistical analysis was performed to compare age, gravida

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Kim, Jooyoung. "Effect of high-dose vitamin C and E supplementation on muscle recovery and training adaptation: a mini review." Physical Activity and Nutrition 27, no. 2 (2023): 008–12. http://dx.doi.org/10.20463/pan.2023.0012.

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[Purpose] This review aimed to investigate the effects of high-dose vitamins C and E supplementation combined with acute or chronic exercise on muscle recovery and training adaptation.[Methods] We used PubMed, Web of Science, and Wiley Online Library databases to perform a literature search based on the keywords ‘vitamin C, vitamin E, antioxidants, muscle recovery, training adaptation, and oxidative stress’.[Results] Vitamin C or E supplementation has been reported to contribute to a reduction in oxidative stress and muscle damage; however, there is currently inadequate evidence of their posit

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Remy, Daniella, Gillian Murphy, Michelle Mravunac, et al. "Vitamins for the Prevention and/or Treatment of COVID-19: An Umbrella Review." CAND Journal 30, no. 4 (2023): 15–31. http://dx.doi.org/10.54434/candj.160.

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Objective: This umbrella review synthesizes the existing literature on the role of vitamins for COVID-19 prevention and management. The objective is to elucidate potential preventive and therapeutic dimensions of these vitamins, highlight clinical applicability, and identify avenues for future research. Methods: A systematic search was conducted using PubMed and Google Scholar, with predefined key words for each vitamin combined with COVID-19-related terms. Narrative and systematic reviews were included, following Cochrane guidelines. AMSTAR scoring was used to assess systematic review quality

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Kusz vel Sobczuk, Iwona, and Anna Święch. "The role of balanced supplementation in diet of age-related macular degeneration patients." OphthaTherapy. Therapies in Ophthalmology 8, no. 1 (2021): 19–25. http://dx.doi.org/10.24292/01.ot.300321.1.

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Aim: The aim of the article was to discuss the role of balanced supplementation in diet of age-related macular degeneration patients. Methods: This review was carried out using comprehensive and systematic literature reports on the role of supplementation of vitamin D, vitamin C, vitamin E, vitamin B6, vitamin B12, zinc, lutein, zeaxanthin, omega-3 acid and folic acid in the prevention of AMD. Results: Vitamins, minerals and carotenoids are essential for the proper retinal function over an inflammation and immune response modulation. Conclusions: Vitamins, minerals and carote

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Bouderlique, Elise, Ellie Tang, Jeremy Zaworski, et al. "Vitamin D and Calcium Supplementation Accelerate Vascular Calcification in a Model of Pseudoxanthoma Elasticum." International Journal of Molecular Sciences 23, no. 4 (2022): 2302. http://dx.doi.org/10.3390/ijms23042302.

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Arterial calcification is a common feature of pseudoxanthoma elasticum (PXE), a disease characterized by ABCC6 mutations, inducing a deficiency in pyrophosphate, a key inhibitor of calcium phosphate crystallization in arteries. Methods: we analyzed whether long-term exposure of Abcc6−/− mice (a murine model of PXE) to a mild vitamin D supplementation, with or without calcium, would impact the development of vascular calcification. Eight groups of mice (including Abcc6−/− and wild-type) received vitamin D supplementation every 2 weeks, a calcium-enriched diet alone (calcium in drinking water),

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Meilana, Intan, and Diyah Eka Andayani. "The Effect of Vitamin D Supplementation During Pregnancy on The Risk of Having Preterm Birth: An Evidence-based Case Report." World Nutrition Journal 5, no. 1 (2021): 61. http://dx.doi.org/10.25220/wnj.v05.i1.0009.

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Introduction: Preterm birth (PTB) is a major cause of neonatal morbidity and mortality. Pregnant women is one of the most vulnerable groups for vitamin D deficiency, that increase the risk of PTB. Vitamin D has the role of immunomodulator, anti-inflammatory, and transcription of genes involved in placental function. Research results on the correlation between vitamin D supplementation and PTB risk are still inconsistent.Objective: To observe the effect of oral vitamin D supplementation during pregnancy on the risk of PTBMethods: Advanced search for relevant literatures in PubMed, Cochrane, and

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Liu, Yaoyuan, Zhifeng Zhong, Jiaxin Xie, Bing Ni, and Yu Wu. "Neuroprotective Roles of Vitamin D: Bridging the Gap Between Mechanisms and Clinical Applications in Cognitive Decline." International Journal of Molecular Sciences 26, no. 15 (2025): 7146. https://doi.org/10.3390/ijms26157146.

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Cognitive function is critical for overall health, with vitamin D’s impact under extensive investigation. This review explores the association between vitamin D and cognitive health, its neuroprotective mechanisms, and the therapeutic potential of supplementation in cognitive decline. Observational studies link low vitamin D levels to increased cognitive deterioration risk, particularly in Alzheimer’s disease, vascular dementia, Parkinson’s disease, and schizophrenia. Clinical trial results on vitamin D supplementation’s cognitive benefits are inconclusive. Vitamin D’s neuroprotective effects

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Pei, Yi-Yan, Yu Zhang, Xing-Chen Peng, Zhe-Ran Liu, Ping Xu, and Fang Fang. "Association of Vitamin D Supplementation with Cardiovascular Events: A Systematic Review and Meta-Analysis." Nutrients 14, no. 15 (2022): 3158. http://dx.doi.org/10.3390/nu14153158.

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Background: low vitamin D status has been associated with an increased incidence of cardiovascular events. However, whether vitamin D supplementation would reduce the incidence of cardiovascular events remains unclear. Purpose: To perform a systematic review and meta-analysis of the effect of vitamin D supplementation on the mortality and incidence of cardiovascular events. Data Sources: We searched Medline, Embase, and the Cochrane Central Register of Controlled Trials from their inception until 3 May 2022. Study Selection: Two authors searched for randomized clinical trials that reported vit

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van Wijnen, Andre J., and Matthew P. Abdel. "Vitamin-D Supplementation." Journal of Bone and Joint Surgery 99, no. 20 (2017): e110. http://dx.doi.org/10.2106/jbjs.17.00888.

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Dobson, Ruth, Hannah R. Cock, Peter Brex, and Gavin Giovannoni. "Vitamin D supplementation." Practical Neurology 18, no. 1 (2017): 35–42. http://dx.doi.org/10.1136/practneurol-2017-001720.

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Vitamin D testing and supplementation is of great interest to neurologists and their patients. Recommended nutritional intakes of vitamin D in the UK remain focused on bone health, despite increasing evidence for a role outside this area. Here we discuss how neurologists might approach vitamin D testing and supplementation, focusing on two conditions associated with vitamin D deficiency that have an increased risk of downstream complications resulting from these: multiple sclerosis and epilepsy. We set out a rationale for testing serum 25-hydroxyvitamin D concentrations and discuss our persona

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Marshall, C. W. "Vitamin E supplementation." American Journal of Clinical Nutrition 49, no. 4 (1989): 718–19. http://dx.doi.org/10.1093/ajcn/49.4.718.

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Drury, Rosalyn, Andreas Rehm, Simran Johal, and Robert Nadler. "Vitamin D Supplementation." Medicine 94, no. 18 (2015): e817. http://dx.doi.org/10.1097/md.0000000000000817.

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