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Journal articles on the topic 'Vitreous hemorrhage (VH)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Li, Meng-Syuan, and Chui-Lien Tsen. "Clinical features and outcomes of breakthrough vitreous hemorrhage secondary to polypoidal choroidal vasculopathy." PLOS ONE 17, no. 12 (2022): e0279778. http://dx.doi.org/10.1371/journal.pone.0279778.

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Polypoidal choroidal vasculopathy (PCV) with hemorrhagic complications is at higher risk for breakthrough vitreous hemorrhage (VH). This study aimed to evaluate the clinical features and outcomes of breakthrough VH secondary to PCV. Data of patients receiving pars plana vitrectomy for breakthrough VH secondary to PCV (VH group) were evaluated retrospectively and compared statistically to data of age and sex-matched PCV patients without breakthrough VH (control group). Among PCV patients, 36 eyes with breakthrough VH and 62 eyes without VH were included. Compared with baseline, best corrected v

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Akanbi, Toyin, Ogugua Ndubuisi Okonkwo, Wilson Ovienria, et al. "Vitreous Hemorrhage in Nigerians." Nigerian Journal of Vitreoretinal Diseases 7, no. 1 (2024): 3–6. http://dx.doi.org/10.4103/njvd.njvd_1_24.

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Abstract Aim: This study aims to determine the prevalence, causes, and systemic associations of vitreous hemorrhage (VH) among Nigerians. Materials and Methods: A multicenter cross-sectional study was conducted from January to December 2018. Data were obtained from patients diagnosed with retinal diseases at the general outpatient and retinal clinics of four eye departments in Nigeria. Patient histories were collected. All patients underwent visual acuity and comprehensive ocular examinations. VH was diagnosed clinically. Patients diagnosed with dense VH underwent ultrasonography. Data analysi

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Vukovic, Dragan. "Natural evolution of experimental vitreous hemorrhage and effects of corticosteroids on its course." Srpski arhiv za celokupno lekarstvo 141, no. 11-12 (2013): 732–37. http://dx.doi.org/10.2298/sarh1312732v.

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Introduction. The course and prognosis of vitreous hemorrhage (VH) are difficult to predict in spite of so far published experimental and clinical studies. Objective. The goal of this study was to follow the course and evaluate prognosis of vitreous hemorrhage. Methods. The experiment was performed on 19 Chinchilla rabbits (Oryctolagus cuniculus), both males and females (38 eyes), weighing 2500-3000 g, which were treated with autologous blood (B) from marginal ear vein - the first group, and the second group was treated with both blood and corticosteroids (B+CS). The course of vitreous hemorrh

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Yilmaz, Uğur, Tahsin Akçaoğlu, Murat Avni Avunduk, Hüseyin Kaya, and Osman Parça. "Investigation of the recurrent vitreous hemorrhage risk factors after early 25G vitrectomy in diabetic vitreous hemorrhage." Medicine 103, no. 3 (2024): e36963. http://dx.doi.org/10.1097/md.0000000000036963.

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Vitreous hemorrhage (VH) is one of the main causes of vision loss in diabetic retinopathy (DRP). Early surgery increases the visibility of the retina, allowing early recognition of DRP complications and additional treatments. One of the most important reasons affecting success after surgery is recurrent vitreous hemorrhage (RVH). We aimed to investigate the risk factors for RVH after early 25G vitrectomy in diabetic VH. Eighty eyes of eighty patients who underwent early 25G PPV surgery with a diagnosis of VH due to proliferative diabetic retinopathy (PDR) were included in this retrospective st

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Wattoo, Rifah Razzaq, Usama Iqbal, and Zeeshan Hameed. "Surgical Outcomes of 23 Gauge Pars Plana Vitrectomy for Non Clearing Diabetic Vitreous Hemorrhage." Journal of Fatima Jinnah Medical University 17, no. 2 (2024): 45–48. http://dx.doi.org/10.37018/jfjmu/zee/1997.

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Background: Vitreous hemorrhage (VH) is one of the main causes of visual loss in patients with Diabetic Retinopathy. Initial management of VH is observation for 4-6 weeks. Non-clearing vitreous hemorrhage (NCVH) remains the most common indication for vitrectomy in such patients. The objective of the study was to investigate the surgical outcomes of 23-gauge vitrectomy with prior intravitreal bevacizumab for non-clearing diabetic vitreous hemorrhage. Patients and Methods: This was a prospective interventional case series conducted at Ophthalmology Department, Allied Hospital, Faisalabad from 1s

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AlHarkan, Dora H., Eman S. Kahtani, Priscilla W. Gikandi, and Ahmed M. Abu El-Asrar. "Vitreous Hemorrhage in Pediatric Age Group." Journal of Ophthalmology 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/497083.

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Purpose.To identify and study causes of vitreous hemorrhage (VH) in pediatric age group and to investigate factors predicting visual and anatomical outcomes.Procedure.A retrospective review of patients aged 16 years or less with the diagnosis of vitreous hemorrhage from January 2005 until December 2010.Results.A total number of 230 patients (240 eyes) were identified. Traumatic vitreous hemorrhage accounted for 82.5%. In cases of accidental trauma, final visual acuity of 20/200 was significantly associated with visual acuity of ≥20/200 at presentation and the absence of retinal detachment at l

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Stringer, Charles E. A., Justin S. Ahn, and Daniel J. Kim. "Asteroid Hyalosis: A Mimic of Vitreous Hemorrhage on Point of Care Ultrasound." CJEM 19, no. 04 (2016): 317–20. http://dx.doi.org/10.1017/cem.2016.358.

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Abstract Point of care ultrasound in the emergency department (ED) is increasingly being used to diagnose time-sensitive, vision-threatening conditions. We present a case of a 64-year-old female who presented to the ED with a three-day history of worsening left eye floaters. Point of care ocular ultrasound demonstrated a posterior chamber containing many echogenic opacities of varying size without acoustic shadowing. Movement of the eye resulted in significant after-movement of these opacities, giving the classic “washing machine” appearance seen with vitreous hemorrhage (VH). Based on these u

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Kim, Dong Yoon, Soo Geun Joe, Seunghee Baek, June-Gone Kim, Young Hee Yoon, and Joo Yong Lee. "Acute-Onset Vitreous Hemorrhage of Unknown Origin before Vitrectomy: Causes and Prognosis." Journal of Ophthalmology 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/429251.

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Purpose. To analyze causes and prognosis of acute-onset preoperatively unknown origin vitreous hemorrhage (VH).Methods. This study included patients who underwent vitrectomy for acute-onset preoperatively unknown origin VH. The underlying causes of VH, which were identified after vitrectomy, were analyzed. And overall visual prognosis of unknown origin VH was analyzed. Risk scoring system was developed to predict visual prognosis after vitrectomy.Results. 169 eyes were included. Among these, retinal vein occlusion (RVO), retinal break, and age-related macular degeneration (AMD) were identified

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Moharana, Bruttendu, Bhumija Bhatt, and Jithin Jacob Varghese. "Traumatic optic nerve head avulsion." Odisha Journal of Ophthalmology 30, no. 1 (2023): 34–36. http://dx.doi.org/10.4103/odjo.odjo_25_23.

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Optic nerve head (ONH) avulsion can lead to irreversible complete loss of vision. The clinical signs are excavated optic disc area, vitreous hemorrhage (VH), preretinal hemorrhage, retinal detachment, and central retinal artery occlusion. Ultrasound (USG) B scan and computed tomography scan help detect the condition where a clear view of the fundus is obscured due to hyphema or VH. This prevents unnecessary treatment. Here, we discuss a case of ONH avulsion, associated complications, and the USG findings.

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Romano, Mario R., Syed Khurshid Gibran, Joaquin Marticorena, David Wong, and Henrich Heimann. "Can an Intraoperative Bevacizumab Injection Prevent Recurrent Postvitrectomy Diabetic Vitreous Hemorrhage?" European Journal of Ophthalmology 19, no. 4 (2009): 618–21. http://dx.doi.org/10.1177/112067210901900416.

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Purpose To evaluate the recurrence of vitreous hemorrhage (VH) in patients treated with intravitreal bevacizumab (IVB) injection (2.5 mg/0.1 mL) intraoperatively at the end of vitrectomy for treatment of diabetic nonclearing VH. Methods A prospective pilot study of 30 eyes of 28 consecutive diabetic patients who underwent pars plana vitrectomy and IVB injection intraoperatively at the end of vitrectomy was performed. The amount of VH was graded with slit lamp biomicroscopy by three masked retinal specialists from grade 0 to grade 3. Main outcome measures were rate of recurrence of the VH, impr

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Ma, Jui-Wen, Jen-Lin Hung, Masaru Takeuchi, Po-Chuen Shieh, and Chi-Ting Horng. "A New Pharmacological Vitreolysis through the Supplement of Mixed Fruit Enzymes for Patients with Ocular Floaters or Vitreous Hemorrhage-Induced Floaters." Journal of Clinical Medicine 11, no. 22 (2022): 6710. http://dx.doi.org/10.3390/jcm11226710.

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Purpose: Ocular floaters caused by vitreous degeneration or blood clots may interfere with various visual functions. Our study investigated the pharmacologic effects of oral supplementation of mixed fruit enzymes (MFEs) for treating spontaneous symptomatic vitreous opacities (SVOs) and those secondary to vitreous hemorrhage (VH). Methods: 224 patients with monocular symptomatic vitreous opacities (SVOs) were recruited between September and December 2017 and received oral supplementation of MFEs (190 mg bromelain, 95 mg papain, and 95 mg ficin) for 3 months in a double-blind clinical trial. Par

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Liu, Zheng-Wei, Chun-Li Chen, Xue-Hao Cui, and Pei-Quan Zhao. "Analysis of the etiologies, treatments and prognoses in children and adolescent vitreous hemorrhage." International Journal of Ophthalmology 14, no. 2 (2021): 299–305. http://dx.doi.org/10.18240/ijo.2021.02.18.

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AIM: To determine the etiologies, treatment modalities and visual outcomes of vitreous hemorrhage (VH; range from birth to 18y). METHODS: A total of 262 eyes from 210 patients between January 2010 and September 2016 were included. All children underwent an appropriate ocular and systemic examination. Data collected included demographics, clinical manifestations, details of the ocular and systemic examination, management details, final fundus anatomy and visual acuity (VA). RESULTS: The most common etiologies were non-traumatic VH (64.89%), most of which were due to retinopathy of prematurity (

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Mamani Maquera, Diego José, and Nahuel Pantoja Dávalos. "Ghost cell glaucoma: Clinic case." Revista de la Facultad de Medicina Humana 23, no. 1 (2023): 121–25. http://dx.doi.org/10.25176/rfmh.v23i1.5061.

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Introduction: Ghost cell glaucoma (GCG) is a very rare secondary open angle glaucoma, in which there is a sustained increase in intraocular pressure (IOP) due to obstruction of the trabecular meshwork (TM) due to the passage of ghost cells (GC) from the vitreous into the anterior chamber, after a vitreous hemorrhage (VH). Clinical Case: We present the case of a male patient with a history of vitreous hemorrhage and sustained IOP elevation in the right eye (RE). Medical treatment was insufficient, for this reason surgical treatment was required. Postoperative evolution was favorable. Conclusion

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Confalonieri, Filippo, Gianmaria Barone, Vanessa Ferraro, et al. "Early versus Late Pars Plana Vitrectomy in Vitreous Hemorrhage: A Systematic Review." Journal of Clinical Medicine 12, no. 20 (2023): 6652. http://dx.doi.org/10.3390/jcm12206652.

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Background: Vitreous hemorrhage (VH) is a common vitreoretinal condition causing impairment of vision due to various etiologies. No consensus exists on the best timing for performing pars plana vitrectomy (PPV) in fundus-obscuring VH. Materials and Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards, we conducted a systematic review of the timing of PPV in VH. We assessed the strength of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach for all the included publications, in accorda

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Padmini H M, Amulya, and Deeptha Vasudevan. "A retrospective study on demographic profile and etiology of vitreous hemorrhage." Indian Journal of Clinical and Experimental Ophthalmology 7, no. 3 (2021): 583–86. http://dx.doi.org/10.18231/j.ijceo.2021.114.

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Vitreous haemorrhage(VH) is due to blood leak from ruptured vessels into the vitreous cavity. It results in painless loss of vision. Visual acuity depends on degree and location of haemorrhage.To study the demographic profile and etiology of all patients with vitreous hemorrhage in tertiary care eye hospital. Medical records of patients who presented with VH between Jan 2017 to July 2018 were retrospectively reviewed. A detailed analysis of records will be noted. Out of 47 patients, 35 were males and 12 were females. Common age group affected were more than 60 years with 22 cases followed by t

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Apriyani, Vina Karina, Grimaldi Ihsan, Rova Virgana, and Iwan Sovani. "Immediate Vs Delayed Vitrectomy for The Management of Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy." Ophthalmologica Indonesiana 48, no. 2 (2022): 46–52. http://dx.doi.org/10.35749/journal.v48i2.100666.

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   Introduction: Surgical approach in vitreous hemorrhage (VH) secondary to diabetic retinopathy remains the procedure of choice for non-clearing VH. However, the most appropriate timing of vitrectomy is yet to be defined. With improvements in surgical techniques, it is reasonable to operate on such patients that have no spontaneous improvement. Objective: To compare the characteristics between groups of patients who underwent immediate and delayed vitrectomy for the management of vitreous hemorrhage due to proliferative diabetic retinopathy (PDR). Methods: Retros

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Gurung, Girija, Anuj Sharma, and Arpita Nayak. "Ghost cell glaucoma secondary to vitreous hemorrhage caused due to ruptured retinal artery macroaneurysm." Indian Journal of Ophthalmology - Case Reports 3, no. 3 (2023): 703–5. http://dx.doi.org/10.4103/ijo.ijo_2900_22.

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A 59 year old diabetic and hypertensive lady with primary open angle glaucoma and past history of non ischemic central retinal vein occlusion presented with vitreous hemorrhage(VH). The VH did not resolve over a 2 month period and led to a sudden rise in intraocular pressure(IOP). Anterior chamber had 2+ khaki colored cells. Gonioscopic examination revealed open angles and no evidence of neovascularization. The IOP was controlled with medical management and vitrectomy was performed for non-resolving VH, which revealed a ruptured retinal artery macroaneurysm (RAM). Our case report contributes t

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Prem, Kumar, and Kishore Mishra Kaushal. "A Hospital Based Etiologic Assessment of Vitreous Hemorrhage in Cases Reported to the Outpatient Department of the Hospital." International Journal of Current Pharmaceutical Review and Research 15, no. 05 (2023): 242–47. https://doi.org/10.5281/zenodo.12619373.

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AbstractAim: The aim of the present study was to determine the etiology of vitreous hemorrhage incases reported to our tertiary care hospital.Methods: A cross-sectional study was conducted among the patients presenting with ocularcomplaints presenting to Department of Ophthalmology, Anugrah Narayan Magadh MedicalCollege and Hospital, Gaya,Bihar, India for one year. Institutional Ethical approval wasobtained for the study. Hundred patients were included in the study. Written consent wastaken from all the patients in the study. A thorough history was taken before a methodical eyeexamination was

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Lim, Jun Hyun, Yong Seop Han, Sang Joon Lee, and Ki Yup Nam. "Risk factors for breakthrough vitreous hemorrhage after intravitreal tissue plasminogen activator and gas injection for submacular hemorrhage associated with age related macular degeneration." PLOS ONE 15, no. 12 (2020): e0243201. http://dx.doi.org/10.1371/journal.pone.0243201.

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Purpose We investigated risk factors for breakthrough vitreous hemorrhage (VH) after an intravitreal tissue plasminogen activator (tPA) and gas injection in patients with submacular hemorrhage (SMH) associated with age-related macular degeneration (AMD). Methods The medical records of patients diagnosed with SMH associated with AMD who received an intravitreal tPA (50 μg/0.05 mL) and perfluoropropane gas (0.3 mL) injection were reviewed retrospectively. We analyzed the associations of breakthrough VH with age, sex, best-corrected visual acuity, intraocular pressure, AMD subtype, accompanying s

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Li, Jun, Wen-chao Hu, Hui Song, Jing-na Lin, and Xin Tang. "Increased Vitreous Chemerin Levels Are Associated with Proliferative Diabetic Retinopathy." Ophthalmologica 236, no. 2 (2016): 61–66. http://dx.doi.org/10.1159/000447752.

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Purpose: To investigate chemerin in the vitreous bodies of patients with proliferative diabetic retinopathy (PDR) and determine the correlation between the levels of vitreous chemerin and vascular endothelial growth factor (VEGF). Methods: This study included 17 patients suffering from PDR and vitreous hemorrhage (VH) (group A), 21 patients with PDR and tractional retinal detachment (TRD) (group B) and 25 patients with idiopathic macular holes or preretinal membranes (control group). All vitreous samples were obtained through pars plana vitrectomy. Enzyme-linked immunosorbent assay and Western

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Ramzi Amin and Rafika. "Successful Visual Rehabilitation Following Pars Plana Vitrectomy and Endolaser in a Patient with Severe Vitreous Hemorrhage due to Proliferative Diabetic Retinopathy." Archives of The Medicine and Case Reports 5, no. 3 (2024): 871–83. https://doi.org/10.37275/amcr.v5i3.742.

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Proliferative diabetic retinopathy (PDR) represents an advanced stage of diabetic eye disease, frequently leading to severe visual impairment through complications such as vitreous hemorrhage (VH). Dense VH significantly obstructs vision and often requires surgical intervention. Pars plana vitrectomy (PPV) coupled with endolaser photocoagulation serves as a critical treatment modality, aiming to clear the hemorrhage, remove tractional elements, and manage the underlying ischemic drive of PDR. This report documents a case demonstrating significant visual recovery after this intervention. A 53-y

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Raza, Ahmad ch. "Diagnostic Accuracy of Ocular Ultrasound in Assessment of Vitreous Hemorrhage and Associated Ocular Diseases." Journal of Health and Rehabilitation Research 4, no. 3 (2024): 1–7. http://dx.doi.org/10.61919/jhrr.v4i3.1243.

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Background: Vitreous hemorrhage (VH) is a significant ophthalmic condition with a yearly incidence ranging from 7.4 to 15.4 per 100,000 people. Its primary causes include proliferative diabetic retinopathy (PDR), ocular trauma, and other retinal vascular disorders. Ocular ultrasound is increasingly utilized as a rapid, non-invasive diagnostic tool to assess vitreous hemorrhage and related ocular conditions. Objective: This study aimed to evaluate the diagnostic accuracy of ocular ultrasound in detecting vitreous hemorrhage and associated ocular diseases in a clinical setting. Methods: A cross-

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Kawakami, Setsuko, Yoshihiro Wakabayashi, Kazuhiko Umazume, et al. "Long-Term Outcome of Eyes with Vitrectomy for Submacular and/or Vitreous Hemorrhage in Neovascular Age-Related Macular Degeneration." Journal of Ophthalmology 2021 (November 2, 2021): 1–8. http://dx.doi.org/10.1155/2021/2963822.

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Purpose. To study long-term clinical outcomes in patients with submacular hemorrhage (SMH) and/or vitreous hemorrhage (VH) associated with neovascular age-related macular degeneration (nAMD) and the real-world clinical situation of adding anti-VEGF therapy after pars plana vitrectomy (PPV). Methods. In this retrospective case series, 25 eyes with SMH and/or VH associated with nAMD were treated by PPV and followed up for at least 24 months. When exudative changes were unresolved or recurred after PPV, additional intravitreal anti-VEGF therapy was given. Results. The reasons for performing PPV w

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Omer Farooq, Bushra Jabbar, Asad Habib, Ubaidullah Yasin, Najia Ahmed, and Fazla Younis. "Efficacy Of Intravitreal Bevacizumab in the Treatment of Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy." Pakistan Armed Forces Medical Journal 73, SUPPL-2 (2023): S333–37. http://dx.doi.org/10.51253/pafmj.v73isuppl-2.4347.

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Objective: To determine the efficacy of intravitreal bevacizumab in the treatment of vitreous hemorrhage secondary to proliferative diabetic retinopathy. Study Design: Quasi-experimental study. Place and Duration of Study: The study was conducted at PNS Shifa Hospital, Karachi Pakistan, from Sep 2018 to Feb 2019. Methodology: The study included 131 patients with proliferative diabetic retinopathy who presented with vitreous hemorrhage. Vitreous hemorrhage was graded into mild-moderate or severe. Patients were randomized into two groups: the bevacizumab group was treated with three intravitreal

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Ding, Yuzhi, Na Su, Jie Luan, Yan Ni, and Zilin Sun. "Effect of Intravitreal Conbercept Injection on Complications of Pars Plana Vitrectomy in Patients with Proliferative Diabetic Retinopathy." Journal of Personalized Medicine 13, no. 4 (2023): 572. http://dx.doi.org/10.3390/jpm13040572.

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Background: The effect of intravitreal conbercept (IVC) before pars plana vitrectomy (PPV) on surgical complications in patients with proliferative diabetic retinopathy (PDR) was observed. Methods: A total of 152 patients with PDR operated on in Jiangsu Provincial People’s Hospital from November 2019 to November 2020 were divided into two groups: 124 patients in the preoperative intravitreal conbercept injection + PPV group (IVC group) and 28 patients in the PPV only group (No-IVC group). Vitreous samples were collected in all eyes of patients who underwent vitrectomy, and the content of VEGF-

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Marcus, Dennis M., Harinderjit Singh, Davis C. Starnes, et al. "Endolaserless Vitrectomy With Intravitreal Aflibercept Injection for Proliferative Diabetic Retinopathy-Related Vitreous Hemorrhage (LASER LESS TRIAL)." Journal of VitreoRetinal Diseases 2, no. 3 (2018): 127–37. http://dx.doi.org/10.1177/2474126418764972.

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Purpose: For proliferative diabetic retinopathy (PDR) eyes not requiring vitrectomy, Diabetic Retinopathy Clinical Research Protocol S and the CLARITY trial demonstrated better visual function and anatomical outcomes with less proliferative and diabetic macular edema consequences in the antivascular endothelial growth factor groups compared to the panretinal photocoagulation groups. Intravitreal aflibercept injection (IAI) may represent a useful therapy with vitrectomy for PDR-related vitreous hemorrhage (VH) as a viable alternative to intraoperative endolaser during vitrectomy. We will determ

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Xu, Yao, and Wei Shen. "Intravitreal conbercept injection with panretinal photocoagulation for high-risk proliferative diabetic retinopathy with vitreous hemorrhage." International Journal of Ophthalmology 17, no. 6 (2024): 1066–72. http://dx.doi.org/10.18240/ijo.2024.06.11.

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AIM: To assess the clinical efficacy and safety of combining panretinal photocoagulation (PRP) with intravitreal conbercept (IVC) injections for patients with high-risk proliferative diabetic retinopathy (HR-PDR) complicated by mild or moderate vitreous hemorrhage (VH), with or without diabetic macular edema (DME). METHODS: Patients diagnosed with VH with/without DME secondary to HR-PDR and received PRP combined with IVC injections were recruited in this retrospective study. Upon establishing the patient’s diagnosis, an initial IVC was performed, followed by prompt administration of PRP. In ca

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Shen, Xi, Yanwei Chen, Yanuo Wang, Lu Yang, and Yisheng Zhong. "Intravitreal Ranibizumab Injection as an Adjuvant in the Treatment of Neovascular Glaucoma Accompanied by Vitreous Hemorrhage after Diabetic Vitrectomy." Journal of Ophthalmology 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/4108490.

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Purpose.To determine the efficacy of intravitreal ranibizumab injection as adjuvant therapy in the treatment of neovascular glaucoma (NVG) accompanied by postvitrectomy diabetic vitreous hemorrhage (PDVH).Methods.Eighteen NVG patients (18 eyes) accompanied by PDVH were enrolled in this prospective, monocenter, 12-month, interventional case series. The consecutive 18 patients with an IOP ≥ 25 mmHg despite being treated with the maximum medical therapy were treated with intravitreal ranibizumab injections. Vitreous surgery or/with Ahmed valve implantation were indicated if no clinical improvemen

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Jirarattanasopa, Pichai, Natthaya Khongsakdinasarn, Mansing Ratanasukon, Patama Bhurayanontachai, and Wantanee Dangboon Tsutsumi. "Visual outcomes of early and late vitrectomy for breakthrough vitreous hemorrhage associated with exudative age-related macular degeneration and polypoidal choroidal vasculopathy." Medicine 102, no. 40 (2023): e35364. http://dx.doi.org/10.1097/md.0000000000035364.

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To compare the visual outcomes of early and late vitrectomy for breakthrough vitreous hemorrhage (VH) associated with exudative age-related macular degeneration (exudative AMD) and polypoidal choroidal vasculopathy (PCV). A retrospective chart review was performed with data of all patients diagnosed with exudative AMD and PCV-related breakthrough VH who underwent early or late vitrectomy (within or after 3 months, respectively). Demographic data and best-corrected visual acuity (BCVA) at baseline, and 1, 3, 6, and 12 months postoperatively were recorded and analyzed. Overall, 105 eyes with bre

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Kishore, Kamal. "Long-Term Management of Complications of Retinal Artery Macroaneurysms with Intravitreal Aflibercept Injection." Case Reports in Ophthalmology 7, no. 3 (2016): 440–49. http://dx.doi.org/10.1159/000449122.

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Purpose: To report the 1-year follow-up results of intravitreal aflibercept injection (IAI) for the management of complications of retinal artery macroaneurysms (RAM). Methods: A retrospective, noncomparative, interventional case series of 4 eyes of 4 patients (all female, aged 68–91 years, 3 treatment naive) treated with IAI 2 mg for complications of RAM [macular edema (ME) 2, submacular hemorrhage (SMH) 1, and vitreous hemorrhage (VH) 1] was conducted. Baseline parameters consisted of complete ocular examination, medical history, best-corrected Snellen VA, fundus photography, IVFA and SD OCT

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Demir, Mehmet, Ersin Oba, Efe Can, Orhan Kara, and Sonmez Cinar. "Effect of Bevacizumab Injection before Vitrectomy on Intravitreal Hemorrhage in Pseudophakic Patients with Proliferative Diabetic Retinopathy." Ophthalmology and Eye Diseases 5 (January 2013): OED.S12352. http://dx.doi.org/10.4137/oed.s12352.

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We evaluated the effect of intravitreal bevacizumab (IVB) injection before pars plana vitrectomy (PPV) on intravitreal hemorrhage (VH) during and after vitrectomy for postoperative the first day and the first month in pseudophakic patients with proliferative diabetic retinopathy (PDR). This retrospective study was performed on 44 eyes of 44 patients who underwent vitrectomy for PDR. Patients were divided into PPV (n = 22 eyes) and PPV + IVB (n = 22 eyes) groups. Injection of bevacizumab (1.25 mg/0.05 mL) was performed 3 days before vitrectomy. Outcomes of visual acuity as well as intraoperativ

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Adriono, Gitalisa Andayani, Sausan Rasyid Mahfudz, and Ichsan Fauzi Triyoga. "Multimodal approach in the diagnosis and management of Eales disease: a case report." Medical Journal of Indonesia 33, no. 4 (2025): 258–62. https://doi.org/10.13181/mji.cr.247454.

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Eales disease is a rare idiopathic occlusive retinal vasculitis with low prevalence in the general population. Its infrequent occurrence limits diagnostic and treatment guidelines, emphasizing the need for ongoing reports to establish effective protocols. This case report describes a patient presenting with symptoms of bilateral retinal vasculitis. Fundus examination revealed vitreous hemorrhage (VH) and peripheral retinal vasculitis. Laboratory and imaging tests were performed to exclude differential diagnoses, leading to Eales disease as the primary diagnosis. Pars plana vitrectomy, panretin

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Kameda, Yusuke, Tadashiro Saeki, Ko Hanai, et al. "Is Chronic Kidney Disease Affecting the Postoperative Complications of Vitrectomy for Proliferative Diabetic Retinopathy?" Journal of Clinical Medicine 10, no. 22 (2021): 5309. http://dx.doi.org/10.3390/jcm10225309.

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Chronic kidney disease (CKD) is a well-known risk factor for postoperative complications in several surgical fields. However, although prevalent among diabetic candidates for vitrectomy, the effect of CKD on vitrectomy outcomes remains unclear. This study aimed at clarifying the relationship between CKD and the occurrence of vitrectomy-related complications in patients with proliferative diabetic retinopathy (PDR). The 6-month incidences of vitreous hemorrhage (VH) and neovascular glaucoma (NVG) following vitrectomy for PDR were compared among the following groups: stages 1–2 CKD (60 patients)

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Gao, Shuang, Zhongjing Lin, Yisheng Zhong, and Xi Shen. "Clinical Efficacy of Preoperative and Intraoperative Intravitreal Ranibizumab as Adjuvant Therapy of Ahmed Glaucoma Valve Implantation Combined with Vitrectomy in the Management of Neovascular Glaucoma with Diabetic Vitreous Hemorrhage." Journal of Personalized Medicine 14, no. 1 (2023): 18. http://dx.doi.org/10.3390/jpm14010018.

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Neovascular glaucoma (NVG) secondary to proliferative diabetic retinopathy (PDR) is a devastating ocular disease with poor prognosis. Intravitreal ranibizumab injection (IVR) has been used as adjuvant therapy of surgical interventions preoperatively or intraoperatively. This study aimed to determine the efficacy and safety of combined IVR as adjuvant therapy in treating NVG with vitreous hemorrhage (VH) in PDR. A total of 39 NVG patients with VH (39 eyes) received IVR 3 to 5 days before surgery, and then they were assigned to either pars plana vitrectomy (PPV) + Ahmed glaucoma valve (AGV) impl

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Josh, Zhaoxu Yuen. "Case report "Acute Retinal Necrosis or not?"." Journal of Clinical Research and Ophthalmology 4, no. 2 (2017): 030–36. https://doi.org/10.17352/2455-1414.000041.

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Acute retinal necrosis (ARN) is a disease including epicleritis or scleritis, periorbital pain, uveitis, vitreous opacity, and necrotizing retinitis. This case looks like ARN except lacking necrotizing retinitis. The epidemiology of ARN is either sex (a slight higher rate on male), any race or any age group (most at 20-50 years). Some patient is immunosuppression (like AIDS) or subclinical immune dysfunction. The incidence of ARN in the UK is one case per 1.6 to 2.0 million populations per year [1]. ARN is responsible for 5.5% of uveitis cases in US. The most common cause of ARN is varicella-z

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Sato, Tomohito, Yuki Takenaka, Yoshiaki Nishio, Masataka Ito, and Masaru Takeuchi. "Anterior Chamber Flare as a Non-Invasive Assessment of Intraocular Immune Status and Ocular Complications in Proliferative Diabetic Retinopathy." International Journal of Molecular Sciences 25, no. 17 (2024): 9158. http://dx.doi.org/10.3390/ijms25179158.

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Proliferative diabetic retinopathy (PDR) is a vision-threatening complication of diabetes mellitus (DM). Anterior chamber (AC) flare and intraocular cytokines are potent biomarkers reflecting the intraocular immune status in PDR. This study aimed to elucidate the complex interrelationship between AC flare and intraocular cytokines in PDR eyes. A retrospective observational study was conducted on 19 PDR eyes of 19 patients with type 2 DM, and on 19 eyes of 19 patients with idiopathic macular hole or epiretinal membrane as controls. AC flare was measured before pars plana vitrectomy (PPV). Aqueo

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Al-Naimy, Mohammed A., Marwa A. M. Khedr, and Yasmine A. Deiaeldin. "Combined preoperative and intraoperative aflibercept injection versus preoperative intravitreal aflibercept injection only in optimizing the anatomical and functional outcomes in diabetic vitrectomy." Delta Journal of Ophthalmology 26, no. 1 (2025): 43–51. https://doi.org/10.4103/djo.djo_62_24.

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Purpose The aim of this study was to evaluate the effect of adding intraoperative aflibercept injection to preoperative injection in optimizing the anatomical and functional outcomes of diabetic vitrectomy compared to preoperative injection only. Patients and methods This retrospective interventional comparative study included 30 eyes of 30 patients scheduled for pars plana vitrectomy for complications of proliferative diabetic retinopathy. The patients were allocated into two groups: group I that received combined preoperative and intraoperative aflibercept (Eylea) injection and group II that

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Li, Yang, Cheng-xun Yang, Guo-ping Qing, and Wen-bin Wei. "Changes in anterior chamber depth following vitrectomy." Chinese Medical Journal 126, no. 19 (2013): 3701–4. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20131604.

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Background Anterior segment morphometry is crucial for ophthalmologists to understand the visual outcomes of cataract surgery, keratorefractive surgery, as well as some other anterior segment disorders. Previous reports in literature have shown that anterior chamber depth (ACD) may shift slightly after vitrectomy. This study aimed to characterize the short-term changes in ACD in eyes after vitrectomy by means of A-scan ultrasound. Methods A prospective case series study was carried out on 29 eyes of 29 patients who underwent vitrectomy as the sole procedure. ACD was measured using A-scan ultra

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Babu, Naresh, Jayant Kumar, Piyush Kohli, Ashish Ahuja, Prerana Shah, and Kim Ramasamy. "Clinical Presentation and Management of Eyes with Globe Perforation during Peribulbar and Retrobulbar Anesthesia: A Retrospective Case Series." Korean Journal of Ophthalmology 36, no. 1 (2022): 16–25. http://dx.doi.org/10.3341/kjo.2021.0090.

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Purpose: To evaluate the clinical presentation, management, and outcome of eyes with an inadvertent globe perforation during peribulbar or retrobulbar block.Methods: This retrospective study evaluated the eyes which had an accidental globe perforation during local ocular anesthesia from 2012 to 2020. The patients were divided into three groups: group 1, Clear media with no rhegmatogenous retinal detachment (RRD); group 2, significant vitreous hemorrhage (VH) precluding the retinal view without RRD; and group 3, RRD with/without VH.Results: Twenty-five patients were included in the study. The m

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Choovuthayakorn, Janejit, Preeyanuch Khunsongkiet, Direk Patikulsila, et al. "Characteristics and Outcomes of Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy Patients in a Limited Resource Tertiary Center over an Eight-Year Period." Journal of Ophthalmology 2019 (March 17, 2019): 1–6. http://dx.doi.org/10.1155/2019/9481902.

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Purpose. To report characteristics and visual results in patients with PDR-associated complications following pars plana vitrectomy (PPV) in a tertiary center over an eight-year period. Methods. Medical records of diabetic retinopathy patients receiving PPV between January 2007 and December 2014 for PDR-related complications were reviewed. Results. A total of 890 consecutive PDR patients were included in the study. PPVs were performed for tractional retinal detachment (36.6%), persistent vitreous hemorrhage (VH) (35.4%), combined tractional and rhegmatogenous retinal detachment (14.5%), and vi

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Shi, XiaoLing, Nuo Dong, Yuanyuan Liang, Lin Zheng, and Xiaobo Wang. "23G Minimally Invasive Vitrectomy Combined with Glaucoma Drainage Valve Implantation and Phacoemulsification Cataract Extraction for Neovascular Glaucoma Secondary to Proliferative Diabetic Retinopathy with Vitreous Hemorrhage." Computational and Mathematical Methods in Medicine 2022 (August 4, 2022): 1–8. http://dx.doi.org/10.1155/2022/7393661.

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Objective. To evaluate the clinical efficacy of the combined application of 23G minimally invasive vitrectomy, glaucoma drainage valve implantation, and phacoemulsification cataract extraction in the treatment of neovascular glaucoma (NVG) secondary to proliferative diabetic retinopathy (PDR) combined with vitreous hemorrhage (VH). Methods. Eighty-three patients (91 eyes) with PDR diagnosed as NVG phase III complicated with VH from June 2018 to May 2020 were selected as the study subjects. The subjects were randomly divided into 3 groups: group A was treated with 23G minimally invasive vitrect

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Hadayer, Amir, Brett H. Mueller, Janelle Fassbender Adeniran, and Charles C. Barr. "Outcomes of Surgically Managed Proliferative Diabetic Retinopathy." Journal of VitreoRetinal Diseases 2, no. 6 (2018): 338–42. http://dx.doi.org/10.1177/2474126418801266.

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Purpose: The purpose of this article is to conduct a retrospective chart review of the results of vitrectomy for diabetic vitreous hemorrhage (VH) and diabetic traction retinal detachment (TRD) using small-gauge instruments. Methods: We retrospectively reviewed medical records of all diabetic vitrectomies performed at the University of Louisville from 2012 to 2016 that had at least 6 months of follow-up. Patients included in this study underwent pars plana vitrectomy (PPV) for proliferative diabetic retinopathy complications. We analyzed the preoperative and 6- and 12-month postoperative visua

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Kang, Eugene Yu-Chuan, Chunya Kang, Wei-Chi Wu, et al. "Association between Add-On Dipeptidyl Peptidase-4 Inhibitor Therapy and Diabetic Retinopathy Progression." Journal of Clinical Medicine 10, no. 13 (2021): 2871. http://dx.doi.org/10.3390/jcm10132871.

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This study aimed to investigate the association of add-on dipeptidyl peptidase-4 inhibitor (DPP4i) therapy and the progression of diabetic retinopathy (DR). In this retrospective population-based cohort study, we examined Taiwanese patients with type 2 diabetes, preexisting DR, and aged ≥40 years from 2009 to 2013. Prescription of DPP4i was defined as a medication possession ratio of ≥80% during the first 6 months. The outcomes included vitreous hemorrhage (VH), tractional retinal detachment, macular edema, and interventions including retinal laser therapy, intravitreal injection (IVI), and vi

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Karimi, Saeed, Homayoun Nikkhah, and Azadeh Haseli Mofrad. "Intravitreal tissue plasminogen activator for treatment of vitreomacular adhesion." International Eye Research 1, no. 2 (2020): 95–101. http://dx.doi.org/10.18240/ier.2020.02.06.

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AIM: To evaluate the role of a single intravitreal injection of tissue plasminogen activator alone (TPA) for treatment of vitreomacular traction and the effect of combined intravitreal TPA and bevacizumab on retinal vascular diseases. METHODS: In this prospective, interventional case series a total of 24 eyes from 24 patients were studied. There were 5 eyes with symptomatic vitreomacular traction syndrome (VMT) and 19 eyes with retinal vascular diseases including diabetic macular edema (DME), diabetic vitreous hemorrhage (VH), central retinal vein occlusion (CRVO) and neovascular age related m

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Danielescu, Ciprian, Andreea Dana Moraru, Nicoleta Anton, et al. "The Learning Curve of Surgery of Diabetic Tractional Retinal Detachment—A Retrospective, Comparative Study." Medicina 59, no. 1 (2022): 73. http://dx.doi.org/10.3390/medicina59010073.

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Background and Objectives: There are few data in the literature concerning the learning curve of tractional retinal detachment (TRD) surgery. We have analyzed the experience gained by a vitreoretinal surgeon over 10 years. Materials and Methods: A retrospective, comparative study of 34 TRD cases operated using 20G instruments between 2008 and 2011 (group A) and 94 cases operated using 23G instruments between 2015 and 2019 (group B). The preoperative characteristics, the type of endotamponade, and the anatomical and functional success were reviewed. Results: The group A patients had a significa

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Takkar, Brijesh, Niroj Kumar Sahoo, Mudit Tyagi, and Vivek Pravin Dave. "Observations on Six Rare Cases of Chorioretinitis Sclopetaria." Nepalese Journal of Ophthalmology 14, no. 1 (2022): 152–61. http://dx.doi.org/10.3126/nepjoph.v14i1.33047.

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Introduction: Chorioretinitis sclopetaria (CS) is a rare consequence of ocular injury. Its association with open globe injury (OGI) and retinal detachment (RD) is controversial. This study evaluates patterns of chorioretinitis sclopetaria and its association with open globe injury and retinal detachment. Case: This is an electronic review of records of a tertiary eye care institute of south India with descriptive analysis of six cases. Cases where fundus findings of chorioretinitis sclopetaria were available were included. Information regarding mode of injury, visual outcomes, follow up and ca

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Dharma, Andhika Guna, Maharani Maharani, Riski Prihatningtias, et al. "ASSOCIATION BETWEEN THE DEGREE OF DIABETIC RETINOPATHY AND DIABETIC MACULAR EDEMA." DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) 11, no. 1 (2022): 59–63. http://dx.doi.org/10.14710/dmj.v11i1.30840.

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INTRODUCTION: WHO estimates more than 150 million diabetes patients worldwide. One of the complications of diabetes is diabetic retinopathy which is recognized as the leading cause of blindness in the working-age population and the cause of 12% of new cases of blindness each year due to macular edema, vitreous hemorrhage, and tractional retinal detachment. Macular edema is the most common cause of decreased visual acuity. The relationship between macular edema and the degree of retinopathy is unclear, so further research is needed. This study aimed to analyze the incidence of macular edema wit

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Hanai, Kaori, Masato Hashimoto, and Hirohiko Nakamura. "Hemorrhagic Macular Cysts in Patients with Terson’s Syndrome Observed through an Ophthalmic Surgical Microscope." Case Reports in Ophthalmology, September 30, 2022, 730–35. http://dx.doi.org/10.1159/000526544.

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The characteristics of hemorrhagic macular cysts (HMCs) in patients with Terson’s syndrome, focusing on the vitreoretinal interface observed through an ophthalmic surgical microscope, are described. Between May 2015 and February 2022, 19 eyes (17 patients) with vitreous hemorrhage (VH) occurring after subarachnoid hemorrhage underwent pars plana vitrectomy. After removing dense VH, 2 of 19 eyes had HMCs. In both cases with HMCs, they formed a dome-like shape and were located beneath the internal limiting membrane (ILM), lying beyond the clean posterior precortical vitreous pocket (PPVP) withou

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Yaoyao, Sun, Deng Kaixin, Li Xiaoxin, et al. "Analysis of non-retinopathy of prematurity (ROP)–related fundus hemorrhage in preterm infants in China." Frontiers in Pediatrics 10 (September 26, 2022). http://dx.doi.org/10.3389/fped.2022.985268.

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ObjectiveTo determine the incidence of fundus hemorrhage (FH) not associated with retinopathy of prematurity (ROP) during ocular screening and report their clinical features, risk factors, therapies, and prognosis in a large population of premature newborns.MethodsThe medical records of all preterm newborns admitted to the Department of Ophthalmology, Peking University People's Hospital, Beijing, from January 1, 2016 through August 31, 2021 were retrospectively reviewed. Fundus examinations were carried out by experienced retinal experts. Examination under anesthesia was carried out in newborn

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Shi, Tingkun, Jing Wen, Honghe Xia, and Haoyu Chen. "Vitrectomy with Subretinal Injection of Recombinant Tissue Plasminogen Activator for Submacular Hemorrhage with or without Vitreous Hemorrhage." Retina, March 6, 2024. http://dx.doi.org/10.1097/iae.0000000000004093.

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Purpose: To evaluate the outcomes and prognostic factors of pars plana vitrectomy (PPV) combined with subretinal injection of recombinant tissue plasminogen activator (rt-PA) for submacular hemorrhage (SMH) patients with or without vitreous hemorrhage. Methods: Sixty-four eyes of 64 patients with SMH patients underwent PPV with subretinal injection of rt-PA. Best-corrected visual acuity (BCVA), SMH displacement, and postoperative complications were analyzed. Predictive factors of the final BCVA were determined using multivariant linear regression. Results: There were 26 eyes with VH and 38 wit

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