Academic literature on the topic 'VRNP'

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Journal articles on the topic "VRNP"

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Han, Julianna, Ketaki Ganti, Veeresh Kumar Sali, et al. "Host factor Rab11a is critical for efficient assembly of influenza A virus genomic segments." PLOS Pathogens 17, no. 5 (2021): e1009517. http://dx.doi.org/10.1371/journal.ppat.1009517.

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It is well documented that influenza A viruses selectively package 8 distinct viral ribonucleoprotein complexes (vRNPs) into each virion; however, the role of host factors in genome assembly is not completely understood. To evaluate the significance of cellular factors in genome assembly, we generated a reporter virus carrying a tetracysteine tag in the NP gene (NP-Tc virus) and assessed the dynamics of vRNP localization with cellular components by fluorescence microscopy. At early time points, vRNP complexes were preferentially exported to the MTOC; subsequently, vRNPs associated on vesicles
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Fontana, Juan, Kellie A. Jurado, Naiqian Cheng, et al. "Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation." Journal of Virology 89, no. 19 (2015): 9765–80. http://dx.doi.org/10.1128/jvi.01522-15.

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ABSTRACTDuring virion maturation, HIV-1 capsid protein assembles into a conical core containing the viral ribonucleoprotein (vRNP) complex, thought to be composed mainly of the viral RNA and nucleocapsid protein (NC). After infection, the viral RNA is reverse transcribed into double-stranded DNA, which is then incorporated into host chromosomes by integrase (IN) catalysis. Certain IN mutations (class II) and antiviral drugs (allosteric IN inhibitors [ALLINIs]) adversely affect maturation, resulting in virions that contain “eccentric condensates,” electron-dense aggregates located outside seemi
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Schreiber, André, Laurita Boff, Darisuren Anhlan, et al. "Dissecting the mechanism of signaling-triggered nuclear export of newly synthesized influenza virus ribonucleoprotein complexes." Proceedings of the National Academy of Sciences 117, no. 28 (2020): 16557–66. http://dx.doi.org/10.1073/pnas.2002828117.

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Influenza viruses (IV) exploit a variety of signaling pathways. Previous studies showed that the rapidly accelerated fibrosarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (Raf/MEK/ERK) pathway is functionally linked to nuclear export of viral ribonucleoprotein (vRNP) complexes, suggesting that vRNP export is a signaling-induced event. However, the underlying mechanism remained completely enigmatic. Here we have dissected the unknown molecular steps of signaling-driven vRNP export. We identified kinases RSK1/2 as downstream targets of virus-activated ERK signaling.
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Bui, Matthew, Elizabeth G. Wills, Ari Helenius, and Gary R. Whittaker. "Role of the Influenza Virus M1 Protein in Nuclear Export of Viral Ribonucleoproteins." Journal of Virology 74, no. 4 (2000): 1781–86. http://dx.doi.org/10.1128/jvi.74.4.1781-1786.2000.

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ABSTRACT The protein kinase inhibitor H7 blocks influenza virus replication, inhibits production of the matrix protein (M1), and leads to a retention of the viral ribonucleoproteins (vRNPs) in the nucleus at late times of infection (K. Martin and A. Helenius, Cell 67:117–130, 1991). We show here that production of assembled vRNPs occurs normally in H7-treated cells, and we have used H7 as a biochemical tool to trap vRNPs in the nucleus. When H7 was removed from the cells, vRNP export was specifically induced in a CHO cell line stably expressing recombinant M1. Similarly, fusion of cells expres
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Gao, Qingxia, Cha Yang, Caiyue Ren, et al. "Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A Virus." Journal of Virology 95, no. 2 (2020): e01391-20. http://dx.doi.org/10.1128/jvi.01391-20.

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ABSTRACTThe viral ribonucleoprotein (vRNP) of the influenza A virus (IAV) is responsible for the viral RNA transcription and replication in the nucleus, and its functions rely on host factors. Previous studies have indicated that eukaryotic translation elongation factor 1 delta (eEF1D) may associate with RNP subunits, but its roles in IAV replication are unclear. Herein, we showed that eEF1D was an inhibitor of IAV replication because knockout of eEF1D resulted in a significant increase in virus yield. eEF1D interacted with RNP subunits polymerase acidic protein (PA), polymerase basic 1 (PB1),
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Hirayama, Etsuko, Hiromitsu Atagi, Akihiro Hiraki, and Jeman Kim. "Heat Shock Protein 70 Is Related to Thermal Inhibition of Nuclear Export of the Influenza Virus Ribonucleoprotein Complex." Journal of Virology 78, no. 3 (2004): 1263–70. http://dx.doi.org/10.1128/jvi.78.3.1263-1270.2004.

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ABSTRACT The influenza virus genome replicates and forms a viral ribonucleoprotein complex (vRNP) with nucleoprotein (NP) and RNA polymerases in the nuclei of host cells. vRNP is then exported into the cytoplasm for viral morphogenesis at the cell membrane. Matrix protein 1 (M1) and nonstructural protein 2/nuclear export protein (NS2/NEP) work in the nuclear export of vRNP by associating with it. It was previously reported that influenza virus production was inhibited in Madin-Darby canine kidney (MDCK) cells cultured at 41°C because nuclear export of vRNP was blocked by the dissociation of M1
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Predicala, Rey, and Yan Zhou. "The role of Ran-binding protein 3 during influenza A virus replication." Journal of General Virology 94, no. 5 (2013): 977–84. http://dx.doi.org/10.1099/vir.0.049395-0.

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Influenza A virus vRNP nuclear export is CRM1-dependent. Ran-binding protein 3 (RanBP3) is a Ran-interacting protein that is best known for its role as a cofactor of CRM1-mediated cargo nuclear export. In this study, we investigated the role of RanBP3 during the influenza A virus life cycle. We found that RanBP3 was phosphorylated at Ser58 in the early and late phases of infection. Knockdown of RanBP3 expression led to vRNP nuclear retention, suggesting that RanBP3 is involved in vRNP nuclear export. Moreover, we demonstrated that the function of RanBP3 during vRNP nuclear export is regulated
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Zhang, Junjie, Gang Li, and Xin Ye. "Cyclin T1/CDK9 Interacts with Influenza A Virus Polymerase and Facilitates Its Association with Cellular RNA Polymerase II." Journal of Virology 84, no. 24 (2010): 12619–27. http://dx.doi.org/10.1128/jvi.01696-10.

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ABSTRACT Influenza virus RNA-dependent RNA polymerase scavenges the 5′ cap from host pre-mRNA to prime viral transcription initiation. It is also well established that viral RNA-dependent RNA polymerase (vRNP) associates with cellular RNA polymerase II (Pol II), on which viral replication depends. Here we report that cyclin T1/CDK9 can interact with influenza virus polymerase and facilitate its association with cellular Pol II. The immunodepletion of cyclin T1/CDK9 totally abolished the association of vRNP with the C-terminal domain (CTD) Ser-2-phosphorylated form of RNA polymerase II. Further
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Zhang, Junsong, Feng Huang, Likai Tan, et al. "Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein." Journal of Virology 90, no. 8 (2016): 3966–80. http://dx.doi.org/10.1128/jvi.03137-15.

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ABSTRACTThe viral ribonucleoprotein (vRNP) complex of influenza A viruses (IAVs) contains an RNA-dependent RNA polymerase complex (RdRp) and nucleoprotein (NP) and is the functional unit for viral RNA transcription and replication. The vRNP complex is an important determinant of virus pathogenicity and host adaptation, implying that its function can be affected by host factors. In our study, we identified host protein Moloney leukemia virus 10 (MOV10) as an inhibitor of IAV replication, since depletion of MOV10 resulted in a significant increase in virus yield. MOV10 inhibited the polymerase a
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Imai, Masaki, Shinji Watanabe, Ai Ninomiya, Masatsugu Obuchi, and Takato Odagiri. "Influenza B Virus BM2 Protein Is a Crucial Component for Incorporation of Viral Ribonucleoprotein Complex into Virions during Virus Assembly." Journal of Virology 78, no. 20 (2004): 11007–15. http://dx.doi.org/10.1128/jvi.78.20.11007-11015.2004.

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ABSTRACT Influenza B virus contains four integral membrane proteins in its envelope. Of these, BM2 has recently been found to have ion channel activity and is considered to be a functional counterpart to influenza A virus M2, but the role of BM2 in the life cycle of influenza B virus remains unclear. In an effort to explore its function, a number of BM2 mutant viruses were generated by using a reverse genetics technique. The BM2ΔATG mutant virus synthesized BM2 at markedly lower levels but exhibited similar growth to wild-type (wt) virus. In contrast, the BM2 knockout virus, which did not prod
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Dissertations / Theses on the topic "VRNP"

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Davis, Alicia Morgan. "CHARACTERIZATION OF INFLUENZA NUCLEOPROTEIN BODY DOMAIN AS ANTIVIRAL TARGET." CSUSB ScholarWorks, 2016. https://scholarworks.lib.csusb.edu/etd/364.

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Influenza is a segmented negative strand RNA virus. Each RNA segment is encapsulated by viral nucleoprotein (NP) and bound by the viral RNA dependent RNA polymerase (RdRP) to form viral ribonucleoproteins (vRNPs) responsible for RNA synthesis. NP is a structural component of the vRNP but also interacts with both viral and host factors to regulate viral RNA expression. NP is conserved among influenza A isolates, making NP interactions compelling antiviral targets. Here I characterize mutations within 5 amino acids of NP that comprise an accessible region of the NP body domain, as determined by
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Prisner, Simon. "Deciphering the assembly of multi-segment genome complexes in influenza A virus." Doctoral thesis, Humboldt-Universität zu Berlin, 2017. http://dx.doi.org/10.18452/18365.

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Influenza A besitzt ein segmentiertes, achtsträngiges Genom in negativer Orientierung. Die einzelnen Segmente sind in virale Ribonukleoproteinkomplexe (vRNPs) verpackt. Genomische Segmentierung erlaubt es Influenza, zwischen verschiedenen Stämmen Reassortierung zu betreiben, was zur Entstehung von hochgradig virulenten und potentiell pandemischen neuen Stämmen führen kann. Die Existenz eines Packungsmechanismus wird vermutet, der sicherstellt dass exakt ein Segment jeden Typs in neu knospende Viren verpackt wird. Es gibt Indizien dafür, dass die vRNPs während ihres Wegs vom Nukleus zur Plasma
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Miyamoto, Sho. "In vitro vRNA-vRNA interactions in the H1N1 influenza A virus genome." Kyoto University, 2020. http://hdl.handle.net/2433/253184.

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Miranda, Tânia Lucia Santos. "Utilização do gel termosensivel poli (n-isopropilacrilamida) na concentração de urina humana visando a obtenção de calicreína humana, em grande escala." Universidade Federal de Minas Gerais, 1990. http://hdl.handle.net/1843/VRNS-9N7P2V.

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No presente trabalho foi feito um estudo da utilização do gel polimérico termosensível poli (N-isopropllacrllamlda) para a concentração da urina humana, visando a obtenção de callcrelna purificada. Este novo processo, ao contrário daqueles convencionalmente utilizados para tal fim, é simples, econômico, "suave", e não apresenta problemas de "scale up". Este estudo envolveu a síntese de géis, a sua utilização para a concentração da urina, e a determinação das melhores condições operacionais do processo. Após a concentração da urina, via gel termosensível, foi feito um estudo da purificação da c
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Tejaswi, Nunna. "Performance Analysis on Hybrid and ExactMethods for Solving Clustered VRP : A Comparative Study on VRP Algorithms." Thesis, Blekinge Tekniska Högskola, Institutionen för datalogi och datorsystemteknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-14112.

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Context: The Vehicle Routing Problem is an NP-hard problem with a combination of varieties oftopics like logistics, optimization research and data mining. There is a vast need of vehicle routingsolutions in day to day like with different constraints. According to the requirements, this problem hasbeen a field of interest to a lot of researchers who incorporate scientific methods to combine andinnovate new solutions to optimize the routing. Being an np-hard problem, it is almost impossible tocompute the solutions to optimality but years of research on this area has paid off quite significantlya
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Fodor, Ervin. "Studies on the vRNA promoter of influenza A virus." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294232.

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Barrett, Lynne. "The role of Arabidopsis VRN1 in mediating the vernalization response." Thesis, University of East Anglia, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423800.

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Rebillas, Loredo Victoria. "The multi-depot VRP with vehicle interchanges." Doctoral thesis, Universitat Politècnica de Catalunya, 2018. http://hdl.handle.net/10803/664634.

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In real-world logistic operations there are a lot of situations that can be exploited to get better operational strategies. It is important to study these new alternatives, because they can represent significant cost reductions to the companies working with physical distribution. This thesis defines the Multi-Depot Vehicle Routing Problem with Vehicle Interchanges (MDVRPVI). In this problem, both vehicle capacities and duration limits on the routes of the drivers are imposed. To favor a better utilization of the available capacities and working times, it is allowed to combine pairs of routes a
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Piatkowska, Kinga. "Das Kino der VRP im DDR-Alltag." Doctoral thesis, Humboldt-Universität zu Berlin, Philosophische Fakultät III, 2011. http://dx.doi.org/10.18452/16429.

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Mit dem Ende des Zweiten Weltkrieges und mit der Proklamierung der DDR im Jahre 1949 wurde ein neues Kapitel in der Geschichte der deutsch-polnischen Beziehungen eröffnet. Die DDR und die Volksrepublik Polen wurden der Regierung der Sowjetunion unterstellt und als „Brüderländer“ aufgefordert, gegenseitige Kontakte in verschiedenen Bereichen zu pflegen. Eines von diesen Gebieten war auch das kulturelle Leben, von dem ein bedeutender Teil der Filmaustausch war. In den Jahren 1949-1990 wurden im Lichtspielwesen der DDR über 300 Spielfilme aus der Volksrepublik Polen verliehen, was zweifelsohne
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Rundquist, Olof. "Påverkar variationer i promotorn till VRN1 frostresistens i vete (Triticum aestivum) från Nordeuropa?" Thesis, Linköpings universitet, Biologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-95557.

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Vete, Triticum aestivum är en mycket viktig matgröda. Under historiens gång har arten fått anpassa sig till många vitt skilda miljöer. I Nordeuropa har frost-resistens varit extra viktigt. En viktig gen för frostresistensen är VRN1som kontrollerar vernaliseringen d.v.s. övergången från vegetativt till aktivt tillstånd som sker på våren. Olika varianter av denna gen leder till skillnader frostresistens under våren. I detta arbete undersöktes hur variationer i promotorn till VRN1A i accessioner från norra Europa påverkar frostresistensen. Alla sorter som kunde sekvenseras visade sig ha samma pro
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Books on the topic "VRNP"

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Pogačnik, Marko. Ko se Boginja vrne. Iskanja, 1993.

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Rossii, Soi︠u︡z pisateleĭ, ред. Russkiĭ narod, russkai︠a︡ kulʹtura i russkiĭ i︠a︡zyk : vystuplenie pisateleĭ Rossii na XI VRNS. Ikhtios, 2007.

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1925-, Stadler Peter, ed. Der Schatzfund von Vrap in Albanien: Beiträge zur Archäologie der Awarenzeit im mittleren Donauraum. Verlag der Österreichischen Akademie der Wissenschaften, 1986.

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Štefančič, Marcel. Ubij vse in vrni se sam: Špageti, peplumi, giallo, mondo, naci-porno, zombiji, kanibali in sublimna logika eurotrasha. UMco, 2002.

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Afonso, Francisco Carlos. Virtual reality transfer protocol (VRTP): Implementing a monitor application for the Real-time Transport Protocol (RTP) using the Java Media Framework (JMF). Naval Postgraduate School, 1999.

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A review of the performance of the Veterans Retraining Assistance Program (VRAP) and the Homeless Veterans Reintegration Program (HVRP): Hearing before the Subcommittee on Economic Opportunity (EO) of the Committee on Veterans' Affairs, U.S. House of Representatives, One Hundred Thirteenth Congress, first session, Thursday, September 12, 2013. U.S. Government Printing Office, 2014.

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VRRP: Increasing Reliability and Failover with the Virtual Router Redundancy Protocol. Pearson Education, 2002.

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ESTEBE, Christian. La vie fugitive mais réelle de Pierre Lombard, VRP. FINITUDE, 2020.

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ESTEBE, Christian. La vie fugitive mais réelle de Pierre Lombard, VRP. FINITUDE, 2020.

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Rock, Nathaniel Max. Standards-Driven Math Vocabulary Ranking Intervention Protocol (VRIP): Pre-Algebra through Geometry (Textbook & Classroom Supplement). Nathaniel Max Rock, 2005.

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Book chapters on the topic "VRNP"

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Shao, Kai, Kang Zhou, Jiang Qiu, and Juan Zhao. "ABC Algorithm for VRP." In Communications in Computer and Information Science. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-45049-9_59.

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Chen, Jian. "Predictability of VRP: Hongkong Evidence." In General Equilibrium Option Pricing Method: Theoretical and Empirical Study. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7428-8_8.

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Chen, Jian. "Predictability of VRP: A Comparison Study." In General Equilibrium Option Pricing Method: Theoretical and Empirical Study. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7428-8_10.

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Chen, Jian. "Predictability of VRP: Other International Evidence." In General Equilibrium Option Pricing Method: Theoretical and Empirical Study. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7428-8_9.

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Simchi-Levi, David, Xin Chen, and Julien Bramel. "The Capacitated VRP with Equal Demands." In The Logic of Logistics. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9149-1_16.

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Simchi-Levi, David, Xin Chen, and Julien Bramel. "The Capacitated VRP with Unequal Demands." In The Logic of Logistics. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9149-1_17.

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Simchi-Levi, David, Xin Chen, and Julien Bramel. "The VRP with Time-Window Constraints." In The Logic of Logistics. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9149-1_18.

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Bramel, Julien, and David Simchi-Levi. "The Capacitated VRP with Equal Demands." In The Logic of Logistics. Springer New York, 1997. http://dx.doi.org/10.1007/978-1-4684-9309-2_5.

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Bramel, Julien, and David Simchi-Levi. "The Capacitated VRP with Unequal Demands." In The Logic of Logistics. Springer New York, 1997. http://dx.doi.org/10.1007/978-1-4684-9309-2_6.

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Bramel, Julien, and David Simchi-Levi. "The VRP with Time Window Constraints." In The Logic of Logistics. Springer New York, 1997. http://dx.doi.org/10.1007/978-1-4684-9309-2_7.

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Conference papers on the topic "VRNP"

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Zubanova, Yu S., V. A. Filobok, E. A. Guenkova, E. R. Davoyan, D. M. Boldakov, and D. S. Mikov. "Identification of allelic combinations of the Ppd-D1, Vrn-A1, Vrn-B1 and Vrn-D1 genes in common wheat lines obtained in the National Center of Grain named after P. P. Lukyanenko." In CURRENT STATE, PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF AGRARIAN SCIENCE. Federal State Budget Scientific Institution “Research Institute of Agriculture of Crimea”, 2020. http://dx.doi.org/10.33952/2542-0720-2020-5-9-10-63.

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An analysis of the allelic composition of the genes determining photoperiodic sensitivity (Ppd-D1) and the need for vernalization (Vrn-A1, Vrn-B1, Vrn-D1) was carried out in 286 common wheat lines obtained in the National Center of Grain named after P. P. Lukyanenko with the use of allele-specific primers. The analyzed samples were distributed over 21 haplotypes; the dominant allele of the Ppd-D1a gene prevailed in the studied material. 123 lines of common wheat carry a combination of D-RRD alleles. The lines that can be attributed to the group of alternate wheat (R-RDR, R-RRD) were identified
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Taylor, Russell M., Thomas C. Hudson, Adam Seeger, Hans Weber, Jeffrey Juliano, and Aron T. Helser. "VRPN." In the ACM symposium. ACM Press, 2001. http://dx.doi.org/10.1145/505008.505019.

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Limet, Sébastien, and Sophie Robert. "FlowVR-VRPN." In the 2008 ACM symposium. ACM Press, 2008. http://dx.doi.org/10.1145/1450579.1450638.

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Perez, Camilo A., and Pablo Figueroa. "VRPN and Qwerk." In the 2008 ACM symposium. ACM Press, 2008. http://dx.doi.org/10.1145/1450579.1450643.

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Sebag, Annabel. "VRP." In SIGGRAPH '15: Special Interest Group on Computer Graphics and Interactive Techniques Conference. ACM, 2015. http://dx.doi.org/10.1145/2745234.2746797.

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Stelzer, Ralph, Erik Steindecker, Stephan Arndt, and Wolfgang Steger. "Expanding VRPN to Tasks in Virtual Engineering." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-34277.

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A high variety of peripherals for the interaction between human and computer is available (e.g. Mouse, Touch and Camera). Therefore the peripherals communicate in different ways with the computer and its applications. The library VRPN is a common, generalized interface between peripherals and VR applications to reduce the development effort. Its main advantages are the system independent client-server architecture with real-time capability and the easy implementation of new peripheral devices. The proposed paper describes the adaption and extension of the VRPN concept to address the challenges
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Kozak, R., and R. Berggren. "Virtual Reality Educational Pathfinders (VREP)." In 2013 3rd Interdisciplinary Engineering Design Education Conference (IEDEC 2013). IEEE, 2013. http://dx.doi.org/10.1109/iedec.2013.6526752.

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Fadl, Ahmed, Zongqin Zhang, Mohammad Faghri, Donna Meyer, and Eric Simmon. "Experimental Investigation on Geometric Effect on Micro Fluidic Diodicity." In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30074.

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The Micro pump is an essential component in a Micro Total Analysis System (μTAS). A feasible and reliable design of the micro pump is a key for the development of the μTAS. The Valve-less Rectification Micro Pump (VRMP) has many advantages, such as: non-moving parts, independent of fluids and channels properties, reliable, and easy to fabricate. Fluid diodicity is an essential parameter of the VRMP design. In this study, we investigate the fluid diodicity (the ratio of forward to reverse flow’s pressure drop) of micro rectifying geometries for more effective design of VRMPs. An experimental ap
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Andrade, Matheus Diógenes, and Fábio Luiz Usberti. "Valid Inequalities for the Green Vehicle Routing Problem." In Encontro de Teoria da Computação. Sociedade Brasileira de Computação - SBC, 2020. http://dx.doi.org/10.5753/etc.2020.11086.

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This work aims to investigate the Green Vehicle Routing Problem (G-VRP), which is an NP-Hard problem that generalizes the Vehicle Routing Problem (VRP) and integrates it with the green logistics. In the G-VRP, electric vehicles with limited autonomy can be recharged at Alternative Fuel Stations (AFSs) to keep visiting customers. This research proposes MILP formulations, valid inequalities, and preprocessing conditions.
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Mulati, Mauro Henrique, and Flávio Keidi Miyazawa. "Tighter Analysis of an Approximation for the Cumulative VRP." In II Encontro de Teoria da Computação. Sociedade Brasileira de Computação - SBC, 2017. http://dx.doi.org/10.5753/etc.2017.3202.

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We deal with the cumulative vehicle routing problem (VRP), a generalization of the capacitated VRP, which objective is to minimize the fuel consumption. Gaur et al. in 2013 gave a 4-approximation based on a well-known partition heuristic to the traveling salesperson problem (TSP). We present a tighter analysis obtaining a 4 3s34Q2 -approximation, where Q is the capacity of the vehicle and s is a scaling factor. To the best of our knowledge, this is the best proved approximation for the cumulative VRP so far.
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Reports on the topic "VRNP"

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Hinden, R., ed. Virtual Router Redundancy Protocol (VRRP). RFC Editor, 2004. http://dx.doi.org/10.17487/rfc3768.

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Nadas, S., ed. Virtual Router Redundancy Protocol (VRRP) Version 3 for IPv4 and IPv6. RFC Editor, 2010. http://dx.doi.org/10.17487/rfc5798.

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Kyparlis, A., R. Parikh, A. Lindem, and M. Zhang. A YANG Data Model for the Virtual Router Redundancy Protocol (VRRP). Edited by X. Liu. RFC Editor, 2018. http://dx.doi.org/10.17487/rfc8347.

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