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1

Karo, Marni Br, Nurfauziah Cahyanti, Farida Simanjuntak, and R. Haryo Bimo Setiarto. "RELATIONSHIP BETWEEN VULVA HYGIENE AND VULVOVAGINALIS CANDIDIASIS OF REPRODUCTION AGE WOMAN IN PUBLIC HEALTH CENTER CIPAYUNG." Jurnal Kesehatan Reproduksi 10, no. 2 (January 3, 2020): 111–16. http://dx.doi.org/10.22435/kespro.v10i2.1364.

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Abstrak Latar belakang: Kandidiasis vulvovaginalis adalah infeksi mukosa pada vagina maupun vulva yang disebabkan oleh jamur Candida. Infeksi terjadi secara akut, subakut, dan kronis, baik endogen maupun eksogen yang menimbulkan keluhan pada vagina. Umumnya infeksi pertama di vagina disebut vulvitis. Tujuan: Penelitian ini bertujuan menganalisis hubungan kebersihan vulva dengan kejadian kandidiasis vulvovaginalis pada usia subur di Puskesmas Kecamatan Cipayung. Metode: Penelitian dilakukan dengan menggunakan pendekatan cross sectional. Penelitian dilakukan pada bulan Februari sampai Juli 2018 di Unit Infeksi Menular Seksual Puskesmas Kecamatan Cipayung. Populasinya adalah sejumlah orang yang datang ke Puskesmas Kecamatan Cipayung. Sampel adalah sebanyak 33 orang, metode pengambilan sampel adalah secara accidental sampling kemudian data dikumpulkan dengan menyebarkan kuesioner dan pemeriksaan laboratorium. Analisis statistik yang digunakan adalah Chi-Square. Hasil: Hasil penelitian menunjukkan bahwa kebersihan vulva tidak baik (75,8%) dan berpengaruh positif terhadap kandidiasis vulvovaginalis di Puskesmas Cipayung (87,9%). Hasil uji statistik diperoleh nilai p = 0,036 (p<0,05), atau ada hubungan kebersihan vulva dengan kejadian kandidiasis vulvovaginalis pada wanita usia subur di Puskesmas Cipayung. Kesimpulan: Kebersihan vulva ada hubungannya dengan kejadian kandidiasis vulvovaginalis di Puskesmas Kecamatan Cipayung. Hal ini disebabkan oleh kurangnya kebersihan vagina pada wanita usia subur yang menyebabkan meningkatnya kejadian kandidiasis. Kata kunci: Kebersihan vulva, kandidiasis vulvovaginalis, wanita usia subur, puskesmas cipayung Abstract Background: Vulvovaginalis candidiasis is infection in the mucosal of vagina or vulva caused by Candida fungus. Infection can occur acutely, subacute, and chronic, both endogenously and exogenously which often cause symptoms in the vagina. Generally, first infection in the vagina called vulvitis. Objective: This study aims to determine the association of the vulva higiene with vulvovaginal candidiasis on fertile age in Cipayung sub-district Public Health Center (PHC). Method: The study used cross sectional design approach. The study was conducted from February to July 2018 in sexually transmitted infection unit. Total sample was 33 patients at Cipayung sub-district PHC. The sampling method is purposive sampling and data were collected by questionnaire and laboratory results. Statistical analysis used is Chi-Square. Results: The results showed that the vulva hygiene was poor (75.8%) and there was positive association with vulvovaginal candidiasis in Cipayung PHC (87.9%). The result of statistical tests obtained p-value = 0.036 (p <0.05), or there is a relationship of vulva hygiene with vulvovaginal candidiasis in women of childbearing age at Cipayung PHC. Conclusion: There is a relationship between vulva hygiene and vulvovaginal candidiasis at Cipayung sub-district PHC due to lack of vaginal hygiene on woman of childbearing age, which increased the incidence of candidiasis. Keywords: Vulva hygiene, vulvovaginal candidiasis, woman age reproductive, public health center cipayung
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2

Mac Bride, Maire B., Deborah J. Rhodes, and Lynne T. Shuster. "Vulvovaginal Atrophy." Mayo Clinic Proceedings 85, no. 1 (January 2010): 87–94. http://dx.doi.org/10.4065/mcp.2009.0413.

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3

Bhesania, A. Hodiwala, and A. Narayankhedkar. "Vulvovaginal Candidosis." International Journal of Current Microbiology and Applied Sciences 6, no. 1 (January 10, 2017): 240–50. http://dx.doi.org/10.20546/ijcmas.2017.601.029.

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4

Edwards, Libby. "Vulvovaginal disease." Current Problems in Dermatology 6, no. 6 (November 1994): 187–216. http://dx.doi.org/10.1016/s1040-0486(05)80010-9.

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5

Nyirjesy, Paul, and Jack D. Sobel. "Vulvovaginal candidiasis." Obstetrics and Gynecology Clinics of North America 30, no. 4 (December 2003): 671–84. http://dx.doi.org/10.1016/s0889-8545(03)00083-4.

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6

Sobel, Jack D. "Vulvovaginal candidosis." Lancet 369, no. 9577 (June 2007): 1961–71. http://dx.doi.org/10.1016/s0140-6736(07)60917-9.

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7

Makela, Paul, Debbie Leaman, and Jack D. Sobel. "Vulvovaginal Trichosporonosis." Infectious Diseases in Obstetrics and Gynecology 11, no. 2 (2003): 131–33. http://dx.doi.org/10.1080/10647440300025510.

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8

Bates, C. M., S. M. Sawyer, G. Bowes, and P. D. Phelan. "Vulvovaginal candidiasis." BMJ 309, no. 6952 (August 13, 1994): 475. http://dx.doi.org/10.1136/bmj.309.6952.475.

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9

Marrazzo, J. "Vulvovaginal candidiasis." BMJ 326, no. 7397 (May 10, 2003): 993–94. http://dx.doi.org/10.1136/bmj.326.7397.993.

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10

Krinsky, Daniel L. "Vulvovaginal candidiasis." Pharmacy Today 25, no. 11 (November 2019): 16. http://dx.doi.org/10.1016/j.ptdy.2019.10.007.

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11

ECKERT, LINDA O., S. E. HAWES, C. E. STEVENS, L. A. KOUTSKY, D. A. ESCHENBACH, and K. K. HOLMES. "Vulvovaginal Candidiasis." Obstetrics & Gynecology 92, no. 5 (November 1998): 757–65. http://dx.doi.org/10.1097/00006250-199811000-00004.

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12

White, D. J., and A. Vanthuyne. "Vulvovaginal candidiasis." Sexually Transmitted Infections 82, suppl_4 (December 1, 2006): iv28—iv30. http://dx.doi.org/10.1136/sti.2006.023168.

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13

KAUFMAN, RAYMOND H. "VULVOVAGINAL DISEASE." Clinical Obstetrics and Gynecology 34, no. 3 (September 1991): 581. http://dx.doi.org/10.1097/00003081-199109000-00013.

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14

KAUFMAN, RAYMOND H. "VULVOVAGINAL DISEASE." Clinical Obstetrics and Gynecology 34, no. 3 (September 1991): 581. http://dx.doi.org/10.1097/00003081-199134030-00013.

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15

Brocklebank, Adam, and Hemant Maraj. "Vulvovaginal candidiasis." InnovAiT: Education and inspiration for general practice 6, no. 10 (September 12, 2013): 643–51. http://dx.doi.org/10.1177/1755738013479944.

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16

MEHTA, AASTA, and GLORIA BACHMANN. "Vulvovaginal Complaints." Clinical Obstetrics and Gynecology 51, no. 3 (September 2008): 549–55. http://dx.doi.org/10.1097/grf.0b013e3181809a26.

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17

Melvin, Louise. "Vulvovaginal Infections." Journal of Family Planning and Reproductive Health Care 34, no. 2 (April 1, 2008): 117. http://dx.doi.org/10.1783/147118908783972384.

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18

Amankwaa, Linda Clark, and Deborah I. Frank. "Vulvovaginal Candidiasis." Nurse Practitioner 16, no. 6 (June 1991): 23–27. http://dx.doi.org/10.1097/00006205-199106000-00004.

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19

Amankwaa, Linda Clark, and Deborah I. Frank. "Vulvovaginal Candidiasis." Nurse Practitioner 16, no. 6 (June 1991): 23–27. http://dx.doi.org/10.1097/00006205-199116060-00004.

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20

Kinghorn, G. R. "Vulvovaginal candidosis." Journal of Antimicrobial Chemotherapy 28, suppl A (January 1, 1991): 59–66. http://dx.doi.org/10.1093/jac/28.suppl_a.59.

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21

Simon, James A. "Vulvovaginal atrophy." Menopause 16, no. 1 (January 2009): 5–7. http://dx.doi.org/10.1097/gme.0b013e3181924701.

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22

Mucitelli, Diane R., Elaine Z. Charles, and Frederick T. Kraus. "Vulvovaginal Polyps." International Journal of Gynecological Pathology 9, no. 1 (January 1990): 20–40. http://dx.doi.org/10.1097/00004347-199001000-00002.

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23

Haefner, Hope K. "Vulvovaginal Disease." Best Practice & Research Clinical Obstetrics & Gynaecology 28, no. 7 (October 2014): 945. http://dx.doi.org/10.1016/j.bpobgyn.2014.07.013.

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24

Bayer, Chelsea, and Laura Parks. "Vulvovaginal Complaints." Current Treatment Options in Pediatrics 2, no. 3 (July 26, 2016): 209–15. http://dx.doi.org/10.1007/s40746-016-0062-8.

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25

Moreira, D., and C. R. Paula. "Vulvovaginal candidiasis." International Journal of Gynecology & Obstetrics 92, no. 3 (January 24, 2006): 266–67. http://dx.doi.org/10.1016/j.ijgo.2005.12.007.

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26

Sari Sovianti, Cyntya, and Mutia Devi. "Recurrent Vulvovaginal Candidiasis." Bioscientia Medicina : Journal of Biomedicine and Translational Research 5, no. 3 (February 17, 2021): 498–507. http://dx.doi.org/10.32539/bsm.v5i3.280.

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Vulvovaginal candidiasis is a common fungal infection caused by Candida Sp,especially Candida albicans. Recurrent vulvovaginal candidiasis was defined asthe occurrence of four or more episodes of vulvovaginal candidiasis in 12 monthsperiod. As many as 9% of women from various populations have recurrentvulvovaginal candidiasis. Vulvovaginal candidiasis affects the quality of life,mental health, and sexual activity. There are many predisposing factors thatcaused recurrent vulvovaginal candidiasis, such as genetics, host, habit,idiopathic and non-albican candida microbes. Management of recurrentvulvovaginal candidiasis includes elimination of predisposing factors; mycologicalculture diagnosis and identification of specific Candida species; followed bymicrobiological examination to confirm the sensitivity of the azole group toCandida sp. Further, oral, or topical therapy should be continued until the patientis asymptomatic and culture-negative. Patients should receive induction therapyfollowed by maintenance suppressive therapy for six months.
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27

Panagiotopoulou, N., C. S. M. Wong, and B. Winter-Roach. "Vulvovaginal-gingival syndrome." Journal of Obstetrics and Gynaecology 30, no. 3 (April 2010): 226–30. http://dx.doi.org/10.3109/01443610903477572.

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28

Davis, Gregory K. "Practical vulvovaginal perspectives." Medical Journal of Australia 185, no. 3 (December 8, 2005): 175. http://dx.doi.org/10.5694/j.1326-5377.2006.tb00493.x.

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29

Wein, Alan J. "Re: Vulvovaginal Atrophy." Journal of Urology 185, no. 6 (June 2011): 2262. http://dx.doi.org/10.1016/s0022-5347(11)60273-5.

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30

Cartwright, Rufus, and Linda Cardozo. "Cosmetic vulvovaginal surgery." Obstetrics, Gynaecology & Reproductive Medicine 18, no. 10 (October 2008): 285–86. http://dx.doi.org/10.1016/j.ogrm.2008.07.008.

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31

Eschenbach, David A. "Chronic Vulvovaginal Candidiasis." New England Journal of Medicine 351, no. 9 (August 26, 2004): 851–52. http://dx.doi.org/10.1056/nejmp048152.

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32

Anderson, Scott R. "Benign vulvovaginal cysts." Diagnostic Histopathology 16, no. 11 (November 2010): 495–99. http://dx.doi.org/10.1016/j.mpdhp.2010.08.004.

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33

Anderson, Scott R. "Benign vulvovaginal cysts." Diagnostic Histopathology 23, no. 1 (January 2017): 14–18. http://dx.doi.org/10.1016/j.mpdhp.2016.11.003.

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34

White, D. J., M. Emens, and M. Shahmanesh. "Recurrent Vulvovaginal Candidosis." International Journal of STD & AIDS 2, no. 4 (July 1991): 235–39. http://dx.doi.org/10.1177/095646249100200401.

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35

TRUMBORE, DAVID J., and JACK D. SOBEL. "Recurrent Vulvovaginal Candidiasis." Obstetrics & Gynecology 67, no. 6 (June 1986): 810–12. http://dx.doi.org/10.1097/00006250-198606000-00012.

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36

SOBEL, JACK D. "Recurrent Vulvovaginal Candidiasis." Obstetrical & Gynecological Survey 42, no. 6 (June 1987): 390–91. http://dx.doi.org/10.1097/00006254-198706000-00018.

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37

SOBEL, JACK D. "Recurrent Vulvovaginal Candidiasis." Obstetrical & Gynecological Survey 42, no. 6 (June 1987): 390–91. http://dx.doi.org/10.1097/00006254-198742060-00018.

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38

Day, Tania, Geoff Otton, Ken Jaaback, and James Scurry. "Vulvovaginal Lichen Planus." Journal of Lower Genital Tract Disease 23, no. 2 (April 2019): 185. http://dx.doi.org/10.1097/lgt.0000000000000465.

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39

Stone, Louise. "Treating vulvovaginal symptoms." Nature Reviews Urology 15, no. 6 (April 16, 2018): 336–37. http://dx.doi.org/10.1038/s41585-018-0010-4.

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40

Kochhar, Suneeta. "Treating vulvovaginal candidiasis." Independent Nurse 2015, no. 3 (February 16, 2015): 35. http://dx.doi.org/10.12968/indn.2015.3.35.

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41

Sobel, Jack D. "Recurrent Vulvovaginal Candidiasis." New England Journal of Medicine 315, no. 23 (December 4, 1986): 1455–58. http://dx.doi.org/10.1056/nejm198612043152305.

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42

Blostein, Freida, Elizabeth Levin-Sparenberg, Julian Wagner, and Betsy Foxman. "Recurrent vulvovaginal candidiasis." Annals of Epidemiology 27, no. 9 (September 2017): 575–82. http://dx.doi.org/10.1016/j.annepidem.2017.08.010.

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43

Sobel, Jack D. "Recurrent vulvovaginal candidiasis." American Journal of Obstetrics and Gynecology 214, no. 1 (January 2016): 15–21. http://dx.doi.org/10.1016/j.ajog.2015.06.067.

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44

Ventolini, G., and M. S. Baggish. "Recurrent vulvovaginal candidiasis." Clinical Microbiology Newsletter 28, no. 12 (June 2006): 93–95. http://dx.doi.org/10.1016/j.clinmicnews.2006.05.004.

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45

Rathod, Sujit D., Jeffrey D. Klausner, Karl Krupp, Arthur L. Reingold, and Purnima Madhivanan. "Epidemiologic Features of Vulvovaginal Candidiasis among Reproductive-Age Women in India." Infectious Diseases in Obstetrics and Gynecology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/859071.

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Background. Vulvovaginal candidiasis is characterized by curd-like vaginal discharge and itching, and is associated with considerable health and economic costs.Materials and Methods. We examined the incidence, prevalence, and risk factors for vulvovaginal candidiasis among a cohort of 898 women in south India. Participants completed three study visits over six months, comprised of a structured interview and a pelvic examination.Results. The positive predictive values for diagnosis of vulvovaginal candidiasis using individual signs or symptoms were low (<19%). We did not find strong evidence for associations between sociodemographic characteristics and the prevalence of vulvovaginal candidiasis. Women clinically diagnosed with bacterial vaginosis had a higher prevalence of vulvovaginal candidiasis (Prevalence 12%, 95% CI 8.2, 15.8) compared to women assessed to be negative for bacterial vaginosis (Prevalence 6.5%, 95% 5.3, 7.6); however, differences in the prevalence of vulvovaginal candidiasis were not observed by the presence or absence of laboratory-confirmed bacterial vaginosis.Conclusions. For correct diagnosis of vulvovaginal candidiasis, laboratory confirmation of infection withCandidais necessary as well as assessment of whether the discharge has been caused by bacterial vaginosis. Studies are needed of women infected withCandidayeast species to determine the risk factors for yeast’s overgrowth.
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46

Azevedo Furtado, Haryne Lizandrey, Brenda Letícia Araujo Motta, Thayariane Lira Mendes, Thayomara Oliveira Da Silva, and Julliana Ribeiro Alves Dos Santos. "FATORES PREDISPONENTES NA PREVALÊNCIA DA CANDIDÍASE VULVOVAGINAL." Revista de Investigação Biomédica 10, no. 2 (April 22, 2019): 190. http://dx.doi.org/10.24863/rib.v10i2.225.

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A Candidíase Vulvovaginal (CVV) é um dos principais problemas ginecológicos. Sua prevalência parece ter aumentado nos últimos anos, evoluindo de 0,5% em 1968 para 22,5% em 1998, época em que se tornou a causa mais comum de infecção da mucosa vulvovaginal. Aproximadamente 5% das mulheres diagnosticadas desenvolvem candidíase vulvovaginal recorrente (CVVR). A CVV possui vários fatores de risco e é resistente a maioria dos antifúngicos. O objetivo deste estudo é analisar a prevalência de candidíase vulvovaginal e os seus fatores de riscos por meio de revisão bibliográfica, análise realizada no período de Janeiro a Julho de 2018, utilizando os descritores: Candidíase Vulvovaginal, Fatores de Risco. As espécies mais predominantes na CVV dependem do local de estudo e os principais fatores predisponentes são a falta de conhecimento sobre a candidíase, fatores geográficos, hábitos culturais, entre outros. Existe uma falta de concordância entre os autores em relação aos fatores de risco, sendo necessárias novas pesquisas para propor medidas preventivas para a candidíase vulvovaginal.
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47

Corimanya, Jorge, Claudia Urbina, and Sonia Pereyra. "TUBERCULOSIS VULVOVAGINAL EN UNA LACTANTE: REPORTE DE CASO." Revista Peruana de Ginecología y Obstetricia 52, no. 4 (April 30, 2015): 262–64. http://dx.doi.org/10.31403/rpgo.v52i322.

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Objetivo: Presentar un caso de lesiones vulvovaginales causadas por tuberculosis, en una lactante con sangrado vaginal. Lugar: Instituto Especializado de Salud del Niño. Paciente: Niña lactante de 7 meses de edad, con tuberculosis vulvovaginal y sistémica, diagnosticada clínica e histopatológicamente. Caso clínico: Tumoración infiltrante de genitales externos, que comprendió la vulva y la vagina, dentro de un cuadro generalizado de sepsis; fue sometida a un examen bajo anestesia y biopsia incisión de la lesión vaginal y del clítoris, encontrándose en el estudio histopatológico hallazgos relacionados con tuberculosis genital, BAAR positivo. La paciente falleció debido a complicaciones derivadas de la tuberculosis sistémica. Conclusión: Aunque es poco común, es importante tener en cuenta este diagnóstico en los casos de tumoraciones genitales infantiles, sobre todo en países con altas tasas de tuberculosis endémica.
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48

Najafian, Mahin, Kobra Shojaei, and Saadat Hajatzadeh. "Evaluation of Fractional CO2 Laser Treatment Efficacy and Comparison to Vaginal Conjugated Estrogen Cream in Postmenopausal Women with Vulvovaginal Atrophy: A Randomized Clinical Trial." Journal of Molecular Biology Research 9, no. 1 (July 11, 2019): 67. http://dx.doi.org/10.5539/jmbr.v9n1p67.

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Background: Vulvovaginal atrophy is common and bothersome among postmenopausal women. Hence in this study, the fractional CO2 laser treatment efficacy was compared with vaginal conjugated estrogen cream in postmenopausal women with vulvovaginal atrophy was assessed. Materials and Methods: In this randomized clinical trial, 130 consecutive postmenopausal women with vulvovaginal atrophy attending to urogynecologic clinic in Imam-Khomeini hospital in Ahvaz in 2015 were enrolled and were randomly assigned to receive either fractional CO2 laser treatment or vaginal conjugated estrogen cream. The improvement of vulvovaginal atrophy symptoms, sexual satisfaction and function were compared across the groups after 12 weeks. Results: There improvement of vulvovaginal atrophy symptoms, sexual satisfaction, and function were 86.2%, 87.7%, and 87.7%, respectively in laser group and 53.8%, 52.3%, and 52.3%, respectively in primarin group showing statistically significant differences (P=0.0001). There were no side effects. Conclusion: Totally, according to obtained results, it may be concluded that efficacy of fractional CO2 laser was higher than vaginal conjugated estrogen cream in postmenopausal women with vulvovaginal atrophy.
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49

Jankovic, Slobodan, Dragica Bojovic, Dubravka Vukadinovic, Elmedina Daglar, Marija Jankovic, Dragomir Laudanovic, Vladan Lukic, et al. "Risk factors for recurrent vulvovaginal candidiasis." Vojnosanitetski pregled 67, no. 10 (2010): 819–24. http://dx.doi.org/10.2298/vsp1010819j.

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Background/Aim. Recurrent vulvovaginal candidiasis is relatively frequent condition, and may have serious health consequences, like chronic vulvovaginal pain syndrome. The aim of our study was to determine possible risk factors for recurrent vulvovaginal candidiasis in non-pregnant females within the reproductive age. Methods. The design of our study was of a case-control type. Case and control patients were selected from the gynecological patients at six primary care facilities in Serbia and in Montenegro. The data on the patients' health condition, concomitant therapy and diseases were taken from their records, and the data on habits were obtained by unstructured interview. For potential risk factors crude odds ratios were calculated, and then adjusted by logistic regression. Results. A total of fifty-one patients had four or more episodes of vulvovaginal candidiasis during the last year (cases), and 132 patients with one to three episodes of vulvovaginal candidiasis were sampled as controls, matched by age. The only two significant associations were found between recurrent vulvovaginal candidiasis and continual wearing of panty liners during the last year (Odds ratio - ORadjusted: 3.97; confidence interval - CI: 1.57-10.02; p = 0.004), and between recurrent vulvovaginal candidiasis and predominant use of vaginal tampons during menstruation in the last year (ORadjusted: 4.25; CI: 1.11-16.27; p = 0.035). The synergistic effect was observed for the concurrent continual wearing of panty liners during the last year and selfmedication with antimycotics. Conclusions. Local factors, like wearing of panty liners or use of tampons during menstruation, may promote recurrence of vulvovaginal candidiasis, especially in patients who practice selfmedication with antimycotics.
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50

Markova, E. A. "Efficacy of metronidazole and miconazole vaginal co-formulation for bacterial vaginosis and vulvovaginal candidiasis." Russian Journal of Woman and Child Health 3, no. 3 (2020): 205–10. http://dx.doi.org/10.32364/2618-8430-2020-3-3-205-210.

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Abstract:
Recurrent vulvovaginal infections being an epidemiological and clinical issue also have social and psychological implications. As a result, the development of the effective diagnostic strategies and therapeutic approaches to female genital infections is important. This paper reviews the most common vulvovaginal infections, i.e., bacterial vaginosis and vulvovaginal candidiasis. Topical metronidazole and miconazole vaginal dosage forms prescribed for these relevant obstetrical gynecological disorders are highlighted. Although numerous domestic and foreign publications on the clinical efficacy of this combination are available, dose reductions and the minimum therapeutically effective doses for bacterial vaginosis, vulvovaginal candidiasis, and mixed vaginitis are still challenging entities. The data on the efficacy of a novel dosage form, Gynocaps® vaginal capsules, containing low doses of miconazole (100 mg) and metronidazole (100 mg) are addressed. The treatment has resulted in microbiological cleaning, the normalization of vaginal WBC count, and the improvement of vaginal florocenosis. In addition, easy-to-use vaginal capsules ensure treatment adherence.KEYWORDS: bacterial vaginosis, vulvovaginal candidiasis, metronidazole, miconazole nitrate, vaginal capsules.FOR CITATION: Markova E.A. Efficacy of metronidazole and miconazole vaginal co-formulation for bacterial vaginosis and vulvovaginal candidiasis. Russian Journal of Woman and Child Health. 2020;3(3):205–210. DOI: 10.32364/2618-8430-2020-3-3-205-210.
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