Relevant bibliographies by topics / W. Somnifera Root Extract

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'W. Somnifera Root Extract'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "W. Somnifera Root Extract"

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Hammood, Mahmood Neamah, Liqaa Hasson Saqban, and Nazar Jebar Metib. "Protective Role of Withania somnifera Against the Adverse Effects of Levofloxacin on Testes Tissue of Rats In Vivo." Medical Journal of Babylon 22, no. 1 (2025): 41–49. https://doi.org/10.4103/mjbl.mjbl_174_23.

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Abstract Background: Medicinal plants have many uses in traditional medicine in all cultures due to their unique therapeutic properties. Withania somnifera is considered an agent to improve sexual health, an antioxidant, anti-aging, and anti-inflammatory. Objective: This study aimed to determine the therapeutic effect of W. somnifera on the potential Levofloxacin-induced testicular injury in rats. Materials and Methods: Thirty adult male Wistar rats were randomly divided into five groups: control group (C), saline-treated for 60 days. Group (W) W. somnifera root extract was orally treated for
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Kumar, Ravi, Rajat Dhariwal, Anurag Kumar, and Miss Minata. "Effect of Withania Somnifera (L.) root extract\'s on PC12 induced by hydrogen peroxide, study." Journal of Pharmaceutical and Biological Sciences 10, no. 2 (2023): 79–82. http://dx.doi.org/10.18231/j.jpbs.2022.015.

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The L. is also used as a crude medicament that mostly effected in various neurological and immunological disorders. It is also known as Ashwagandha and “Indian ginseng” in Indian region. There is a lack of information on the possible neuroprotective properties of W. somnifera root against HO- and Ab(1-42)-induced cytotoxicity, which are now targeted for innovative treatments for dementia, particularly dementia of the Alzheimer's type (AD). According to this research, we prepared an aqueous extract of dried roots of W. somnifera that possess the protective effect against Ab- aggregated fibril a
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Devaraj Reddy KN, Srilakshmi Aluri, Prathvi Shetty, et al. "Assessing the Efficacy and Biological Benefits of Withanolide-rich Withania somnifera Root Extract." Annual Research & Review in Biology 39, no. 5 (2024): 54–64. http://dx.doi.org/10.9734/arrb/2024/v39i52081.

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The medicinal plant Withania somnifera, usually referred to as Ashwagandha, is a member of the Solanaceae family. The presence of Withanolides in the roots is responsible for a number of pharmacological effects in Ashwagandha. Withanolides have been demonstrated to be an effective neuronal, immune, anti-stress, and anti-cancer agent. However, Withanolides demonstrated limited permeability, lowering the bioavailability and efficacy of active compounds. The goal of the study was to ascertain the biological efficacy of Ashwagandha Composition, a blend of W. somnifera milk extract and water extrac
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Lingfa, Lali, Aravinda Tirumala, and Srinivas Ankanagari. "In Vitro Cytotoxicity of Reproductive Stage Withania somnifera Leaf and Stem on HepG2 Cell Line." Evidence-Based Complementary and Alternative Medicine 2023 (December 26, 2023): 1–10. http://dx.doi.org/10.1155/2023/8832166.

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Background. The ayurvedic plant Withania somnifera, a member of the Solanaceae family, has been used as a remedy for diverse health problems, including cancer. Objectives. The objective of this investigation was to conduct a comparative analysis of the in vitro cytotoxic properties of methanolic extracts derived from the leaf, stem, and root of W. somnifera on HepG2 and L929 cell lines. Methods. Methanolic extracts were obtained using the Soxhlet extraction method. To assess the in vitro anticancer action on the HepG2 and L929 cell lines, an MTT assay was performed. Changes in cell morphology
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Sharma, Mamta, Rupinder Kaur, and Sunil Puri. "BIO-HERBICIDAL EFFICIENCY OF WITHANIA SOMNIFERA AGAINST IMPORTANT HIMALAYAN WEEDS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 3 (2017): 88. http://dx.doi.org/10.22159/ijpps.2017v9i3.14740.

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Objective: The aim of the study was to evaluate the bioherbicidal activity of Withania somnifera against germination and growth of noxious weeds of Himalaya i.e. Ageratum coenyzoides, Chenopodium album and Achyranthus aspera in a laboratory and foliar spray bioassay which will act as a tool of weed management in the Himalayan region.Methods: Root, stem and leaf aqueous extract of Withania somnifera at 100% concentration were applied to determine their effect on the seed germination and seedling growth of tested weeds under laboratory condition. Foliar spray bioassay was carried out by spraying
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Alsabaa, Zein Husam, Luay Abu-Qatouseh, Kenza Mansoor, et al. "Pharmacokinetic and pharmacodynamic effects of Withania somnifera (L.) Dunal (ashwagandha) and carbamazepine combination in rats." Journal of Pharmacy & Pharmacognosy Research 13, no. 3 (2025): 925–32. https://doi.org/10.56499/jppres24.2088_13.3.925.

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Context: Withania somnifera, also known as ashwagandha, has antibacterial, anti-inflammatory, anticonvulsant, and anti-diabetic properties and reduces stress. Carbamazepine is one of the most used antiepileptic medications for treating epilepsy. Aims: To investigate the pharmacokinetics and pharmacodynamics of carbamazepine versus W. somnifera extract combination in vivo in healthy rat plasma using high-performance liquid chromatography. Methods: The carbamazepine levels were analyzed using validated high-performance liquid chromatography. The gamma-aminobutyric acid in the serum was performed
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Javaid, Arshad, and Roma Akhtar. "ANTIFUNGAL ACTIVITY OF METHANOLIC ROOT EXTRACT OF WITHANIA SOMMNIFERA AGAINST FUSARIUM OXYSPORUM F. SP. CEPAE." African Journal of Traditional, Complementary and Alternative Medicines 12, no. 5 (2015): 22–27. http://dx.doi.org/10.21010/ajtcam.v12i5.4.

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Background: Basal rot of onion (Allium cepa L.) caused by Fusarium oxysporum f. sp. cepae is a common soil-borne disease that causes significant yield losses. Generally, synthetic fungicides are used to combat the menace which cause environmental pollution. The present study was carried out to assess the antifungal activity of Withania somnifera (L.) Dunal, a Solanaceous medicinal plant, against the pathogen of this disease. 
 Materials and Methods: Different concentrations (from 0.5 to 4%) of methanolic extract of root, stem and fruit of the test plant species were prepared and their bio
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Kushwaha, Vimlesh. "Nephroprotection of Withania somnifera root extract against gentamicin induced nephrotoxicity: a histological evaluation in experimental Wistar rats." International Journal of Basic & Clinical Pharmacology 8, no. 10 (2019): 2297. http://dx.doi.org/10.18203/2319-2003.ijbcp20194275.

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Background: Gentamicin, an aminoglycoside group of drug, used against aerobic gram negative bacteria, is known for nephrotoxicity. Herbal products have a special place in the world of pharmaceuticals with their safety, efficacy and cost effectiveness. Withania somnifera (Ashwagandha) roots had known since long for its antioxidant status and free radical scavenging property. So W. somnifera can be used as nephroprotective agent because of free radical scavenging property.Methods: Total 54 rats were randomised in 3 groups named G10, G20 and G30 according to 10, 20 and 30 days of treatment. In ea
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Wiciński, Michał, Anna Fajkiel-Madajczyk, Zuzanna Kurant, et al. "Ashwagandha’s Multifaceted Effects on Human Health: Impact on Vascular Endothelium, Inflammation, Lipid Metabolism, and Cardiovascular Outcomes—A Review." Nutrients 16, no. 15 (2024): 2481. http://dx.doi.org/10.3390/nu16152481.

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Withania somnifera, commonly known as Ashwagandha, has been popular for many years. Numerous studies have shown that the extract of this plant, due to its wealth of active substances, can induce anti-inflammatory, neuroprotective, immunomodulatory, hepatoprotective, cardioprotective, anti-diabetic, adaptogenic, anti-arthritic, anti-stress, and antimicrobial effects. This review examines the impact of Ashwagandha extract on the vascular endothelium, inflammation, lipid metabolism, and cardiovascular outcomes. Studies have shown that Ashwagandha extracts exhibit an anti-angiogenic effect by inhi
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Gaurav, Isha, Tanuja Singh, Abhimanyu Thakur, et al. "Synthesis, In-Vitro and In-Silico Evaluation of Silver Nanoparticles with Root Extract of Withania somnifera for Antibacterial Activity via Binding of Penicillin-Binding Protein-4." Current Pharmaceutical Biotechnology 21, no. 15 (2020): 1674–87. http://dx.doi.org/10.2174/1389201021666200702152000.

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Background: Metal Nanoparticles (NPs) have been widely used for various applications in biomedical sciences, including in drug delivery, and as therapeutic agents, but limited owing to their toxicity towards the healthy tissue. This warrants an alternative method, which can achieve the desired activity with much reduced or no toxicity. Being a biological product, Withania somnifera (W. somnifera) is environment friendly, besides being less toxic as compared to metal-based NPs. However, the exact mechanism of action of W. somnifera for its antibacterial activities has not been studied so far. O
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Dissertations / Theses on the topic "W. Somnifera Root Extract"

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MACCIONI, RICCARDO. "Phytomedicinal approach toward the treatment of CNS disorders: behavioural and biochemical evaluation of the effects of a methanolic dry root extract of Withania somnifera and its isolated metabolite, Docosanyl Ferulate, in rodent models of anxiety and drug addiction." Doctoral thesis, Università degli Studi di Cagliari, 2022. http://hdl.handle.net/11584/332548.

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The use of phytomedicinal remedies has increased during the last decades thanks to the relative low cost, low toxicity, and potential synergic effects of plant-derived medications. Withania somnifera (WS), commonly known as Indian Ginseng, is a medical plant belonging to the Indian Traditional Medical System, the Ayurveda. In preclinical studies, WS has shown an impressive variety of therapeutic effects in several pathological conditions. Among these effects, the anxiolytic and antiaddictive properties of this plant are the ones discussed in this work of thesis. Both effects have been attribu
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Book chapters on the topic "W. Somnifera Root Extract"

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Madhu, Nithar Ranjan, Bhanumati Sarkar, Nikhil Chandra Halder, and Biplab Kumar Behera. "Potential Applications of Traditional Medicinal Plants for Treating Sleep Disorders." In The Basic Handbook of Indian Ethnobotany and Traditional Medicine, 2nd ed. International Academic Publishing House (IAPH), 2023. http://dx.doi.org/10.52756/bhietm.2023.e02.015.

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Sleep disorders involve conditions such as insomnia, sleep apnoea and restless leg syndrome and they are realised in almost everyone ranging from children to the elderly globally. To this time, folk medicinal practices in India including West Bengal are rich in terms of Ayurveda, Unani and folk medicine: a number of herbs from these practices have been used to cure sleep disorders. Hence, vegetation and herbal medicine like Valerian (Valeriana officinalis), Chamomile (Matricaria chamomilla), Passionflower (Passiflora incarnata), Ashwagandha (Withania somnifera), Lemon Balm (Melissa officinalis
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Conference papers on the topic "W. Somnifera Root Extract"

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"The Protective Effect of Withania somnifera Root Extract Against Acetaminophen Induced Liver Toxicity in Cyprinus carpio Compared to Silymaryn." In International Conference on Chemical, Environment & Biological Sciences. International Institute of Chemical, Biological & Environmental Engineering, 2014. http://dx.doi.org/10.15242/iicbe.c914122.

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Sinha, Pratima, and Suzanne Ostrand-Rosenberg. "Abstract 4718: Withaferin A, a potent and abundant component of Withania somnifera root extract, reduces myeloid-derived suppressor cell function." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4718.

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Lin, Bochuan, Shen Zhu, Heng Ban, et al. "Thermal Property Measurement of Semiconductor Melt Using Modified Laser Flash Method." In ASME 2003 Heat Transfer Summer Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/ht2003-47448.

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This study further develops the standard laser flash method for the measurement of multiple thermal properties of semiconductor melts. The standard laser flash method is widely used to measure thermal diffusivity of solids. Our modified procedure allows thermal diffusivity, thermal conductivity, and specific heat capacity of molten semiconductor material to be determined simultaneously. The transient heat transfer process in the melt and its quartz container was computationally studied in detail. A fitting procedure based on the numerical result and the least root-mean-square error fitting to
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Shrestha, Sundar, Anand Koirala, Maksym Spiryagin, and Qing Wu. "Wheel-Rail Interface Condition Estimation via Acoustic Sensors." In 2020 Joint Rail Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/jrc2020-8037.

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Abstract The surface roughness between the wheel and rail has a huge influence on the rolling noise level. The presence of the third body such as frost or grease at the wheel-rail interface contributes towards change in adhesion coefficient resulting in the generation of acoustic noise at various levels. Therefore, it is possible to estimate adhesion conditions between the wheel and rail from the analysis of audio patterns originating from wheel-rail interaction. In this study, a new approach to estimate adhesion condition is proposed which takes rolling noise as input. Acoustic sensors (Behri
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Reports on the topic "W. Somnifera Root Extract"

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Singh, Vineet, and Deepak Mundkinajeddu. Adulteration of Ashwagandha (Withania somnifera) Roots and Extracts. ABC-AHP-NCNPR Botanical Adulterants Prevention Program, 2019. https://doi.org/10.59520/bapp.bapb/gsha8763.

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The goal of this bulletin is to provide information and/or updates on the issue of adulteration of ashwagandha (Withania somnifera, Solanaceae) root materials and their extracts to the international herbal products industry and extended natural products community in general. It is intended to complement the previously published work on W. somnifera root and extract adulteration, i.e., the American Herbal Pharmacopoeia monograph by Upton et al.1 and the article by Mundkinajeddu et al.2 by reporting new data on the occurrence of adulteration, the market situation, and its subsequent consequences
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Journal articles
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