Relevant bibliographies by topics / Wakayin

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  2. Dissertations / Theses
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Academic literature on the topic 'Wakayin'

Author: Grafiati
Published: 4 June 2021
Last updated: 4 February 2022

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Journal articles on the topic "Wakayin"

1

Barret, Roland, and Nathalie Roue. "Synthesis of a bis-pyrrolo-quinone structure analogue to wakayin." Tetrahedron Letters 40, no. 20 (May 1999): 3889–90. http://dx.doi.org/10.1016/s0040-4039(99)00640-1.

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Hoang, Hung, Xiaofen Huang, and Edward B. Skibo. "Synthesis and in vitro evaluation of imidazole-based wakayin analogues." Organic & Biomolecular Chemistry 6, no. 17 (2008): 3059. http://dx.doi.org/10.1039/b806883f.

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Copp, Brent R., Chris M. Ireland, and Louis R. Barrows. "Wakayin: a novel cytotoxic pyrroloiminoquinone alkaloid from the ascidian Clavelina species." Journal of Organic Chemistry 56, no. 15 (July 1991): 4596–97. http://dx.doi.org/10.1021/jo00015a005.

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Barret, Roland, and Nathalie Roue. "ChemInform Abstract: Synthesis of a Bis-pyrrolo-quinone Structure Analogue to Wakayin." ChemInform 30, no. 35 (June 13, 2010): no. http://dx.doi.org/10.1002/chin.199935134.

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Legentil, Laurent, Brigitte Lesur, and Evelyne Delfourne. "Aza-analogues of the marine pyrroloquinoline alkaloids wakayin and tsitsikammamines: Synthesis and topoisomerase inhibition." Bioorganic & Medicinal Chemistry Letters 16, no. 2 (January 2006): 427–29. http://dx.doi.org/10.1016/j.bmcl.2005.09.063.

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Legentil, Laurent, Laurent Benel, Viviane Bertrand, Brigitte Lesur, and Evelyne Delfourne. "Synthesis and Antitumor Characterization of Pyrazolic Analogues of the Marine Pyrroloquinoline Alkaloids: Wakayin and Tsitsikammamines." Journal of Medicinal Chemistry 49, no. 10 (May 2006): 2979–88. http://dx.doi.org/10.1021/jm051247f.

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Levy, Thomas, Laura Marchand, Vincent Stroobant, Luc Pilotte, Benoît Van den Eynde, Frédéric Rodriguez, and Evelyne Delfourne. "IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines." Bioorganic & Medicinal Chemistry Letters 40 (May 2021): 127910. http://dx.doi.org/10.1016/j.bmcl.2021.127910.

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Nguyen, Thao, Dwayaja Nadkarni, Shilpa Dutta, Su Xu, Sanghun Kim, Srinivasan Murugesan, and Sadanandan Velu. "Synthesis of Pyrroloquinones via a CAN Mediated Oxidative Free Radical Reaction of 1,3-Dicarbonyl Compounds with Aminoquinones." Journal of Chemistry 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/262580.

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Pyrroloquinone ring systems are important structural units present in many biologically active molecules including a number of marine alkaloids. For example, they are found in a series of marine metabolites, such as tsitsikammamines, zyzzyanones, wakayin, and terreusinone. Several of these alkaloids have exhibited antimicrobial, antimalarial, antifungal, antitumor, and photoprotecting activities. Synthesis of pyrroloquinone unit is the key step in the synthesis of many of these important organic molecules. Here, we present a ceric (IV) ammonium nitrate (CAN) mediated oxidative free radical cyclization reaction of 1,3-dicarbonyl compounds with aminoquinones as a facile methodology for making various substituted pyrroloquinones. 1,3-dicarbonyl compounds used in this study are ethyl acetoacetate, acetylacetone, benzoyl acetone, andN,N-dimethyl acetoacetamide. The aminoquinones used in this study are 2-(benzylamino)naphthalene-1,4-dione and 6-(benzylamino)-1-tosyl-1H-indole-4,7-dione. The yields of the synthesized pyrroloquinones ranged from 23–91%.
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Kokoshka, Jerry M., Todd L. Capson, Joseph A. Holden, Chris M. Ireland, and Louis R. Barrows. "Differences in the topoisomerase I cleavage complexes formed by camptothecin and wakayin, a DNA-intercalating marine natural product." Anti-Cancer Drugs 7, no. 7 (September 1996): 758–65. http://dx.doi.org/10.1097/00001813-199609000-00007.

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Zhang, Liming, Michael P. Cava, Robin D. Rogers, and Lillian M. Rogers. "Synthesis of a wakayin model compound: Oxidative formation of a new pyrrole ring in the indol-3-yl-indoloquinone system." Tetrahedron Letters 39, no. 42 (October 1998): 7677–78. http://dx.doi.org/10.1016/s0040-4039(98)01718-3.

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Dissertations / Theses on the topic "Wakayin"

1

Levy, Thomas. "Synthèse totale d'un alcaloïde marin : Wakayine et étude d'analogues ayant une activité immunothérapeutique potentielle." Thesis, Toulouse 3, 2020. http://www.theses.fr/2020TOU30256.

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Les alcaloïdes marins Wakayine et Tsitsikammamine appartiennent à la famille des 1,3,4,5-tétrahydropyrrolo[4,3,2-de] quinolines. Récemment, certains analogues de ces molécules ont été décrits comme inhibant l'indoleamine 2,3-dioxygénase (IDO1), une enzyme impliquée dans la capacité qu'ont certaines tumeurs à supprimer une grande partie de la réponse immunitaire potentielle. Ainsi, l'IDO1, de même que la tryptophane-2,3-dioxygénase (TDO), qui est une enzyme apparentée catalysant la même réaction, sont des cibles thérapeutiques potentielles dans la lutte contre le cancer. L'étude réalisée pour mettre au point une synthèse totale de la wakayine est décrite. Les différentes stratégies envisagées sont basées sur la construction d'un motif bis-pyrroloquinone : la première fait intervenir une réaction d'addition de Michael entre une 3-éthylamine-indoledione diversement protégée et une β-hydroxyamine, la deuxième qui constitue une voie originale pour aboutir au motif bispyrroloquinone met en jeu une indoledione et la methyltryptamine et la troisième consiste en la condensation d'un acétal sur une 6-benzyl-3-substituée-indoledione. Sur la base d'une étude structurale complète d'IDO1 et d'une étude de docking, des inhibiteurs potentiels ont été préparés. Leur capacité à inhiber IDO1 et TDO a été évaluée avec un test cellulaire. Certains composés présentent des activités intéressantes
The marine alkaloids Wakayin and Tsitsikammamine belong to the 1,3,4,5-tetrahydropyrrolo [4,3,2-de] quinoline family. Recently, some analogues of these molecules have been described as inhibiting indoleamine 2,3-dioxygenase (IDO1), an enzyme involved in the ability of some tumors to suppress most of immune response. Thus, IDO1, along with tryptophan-2,3-dioxygenase (TDO), a related enzyme catalyzing the same reaction, are potential therapeutic targets in the fight against cancer. The study carried out to develop a total synthesis of wakayin is described. The various strategies considered are based on the construction of a bis-pyrroloquinone unit: the first involves a Michael addition reaction between a 3-ethylamine-indoledione variously protected and a β-hydroxyamine, the second which constitutes an original route to end up with the bispyrroloquinone unit involves an indoledione and methyltryptamine and the third consists of the condensation of an acetal on a 6-benzyl-3-substituted-indoledione. Based on a comprehensive structural study of IDO1 and a docking study, potential inhibitors have been prepared. Their ability to inhibit IDO1 and TDO was evaluated in a cellular test. Certain compounds exhibit interesting activities
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2

Mauzé, Marie. "Les fils de Wakai : une histoire des Indiens Lekwiltoq /." Paris : Ed. Recherche sur les civilisations, 1992. http://catalogue.bnf.fr/ark:/12148/cb355511652.

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Texte remanié de: Th. 3e cycle--Ethnol.--Paris--EHESS, 1985. Titre de soutenance : Enjeux et jeux de prestige, des Kwagul méridionaux aux Lekwiltoq.
En appendice un choix de documents en français et en anglais. Bibliogr. p. 133-144.
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3

Legentil, Laurent. "Etude d'aza-analogues des alcaloïdes marins de type pyrroloquinoline, wakayine et tsitsikammamines à activité antitumoral potentielle : approche vers la synthèse totale des produits naturels." Toulouse 3, 2004. http://www.theses.fr/2004TOU30283.

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Les alcaloïdes marins wakayine et tsitsikammamines A et B appartiennent à la famille des 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolines. Ces molécules présentent des propriétés cytotoxiques qui pourraient être liées à l'inhibition des topoisomérases I et II. La synthèse de deux types d'aza-analogues de ces alcaloïdes a été réalisée (analogues pyrazoloquinolines et pyrroloquinolines). Le noyau pyrazole est obtenu via une réaction de cycloaddition dipolaire [3+2] entre des quinones variées et des espèces diazo-alkyles ou -aryles. Le noyau iminoquinone est ensuite formé par cyclisation intramoléculaire. Les différents intermédiaires de synthèse ont été évalués vis-à-vis de leurs propriétés cytotoxiques in vitro sur 5 lignées cellulaires différentes, ainsi que vis-à-vis de l'inhibition des topoisomérases I et II. De nombreuses molécules inhibent l'une ou les deux topoisomérases alors que peu de composés présentent une activité cytotoxique (de l'ordre du micromolaire). La synthèse totale de ces alcaloïdes a été étudiée. Le schéma de rétrosynthèse est basé sur une réaction d'addition de Michael entre une 3-éthylamine-indole-dione et des β-cétoamines diversement protégées. Un analogue ouvert des tsitsikammamines à ainsi été obtenu
The marine alkaloids wakayin and tsitsikammamines A and B belong to the 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolines family. They both possess cytotoxic properties which seem related to inhibition of topoisomérases I and II. Two series of aza-analogues of these compounds (pyrazoloquinolines and pyrroloquinolines analogues) have been investigated. The pyrazole ring was obtained on the basis of a [3+2] dipolar cycloaddition reaction between various quinones and diazo species (alkyls or aryls). The iminoquinone moiety was then formed through an intramolecular cyclisation. The different compounds have been evaluated for both in vitro cytotoxic activity against 5 dictinct cancer cell lines and topoisomérases I and II inhibition. Most of the compounds inhibit one or the two enzymes whereas only few of them exhibit cytotoxic activity with IC50 values of micromolar order. The total synthesis of the natural alkaloids has also been studied. The retrosynthetic pathway was based on a Michael addition between 3-éthylamine-indoledione and different protected β-cétoamines. An original analogue of tsitsikammamines has been obtained
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4

Gaudioso, Roberto. "Kuwako na wakati: mipaka ya lugha kama hatua za falsafa katika mashairi ya Euphrase Kezilahabi." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-162808.

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This paper is a contribution to the 26th Swahili Colloquium in Bayreuth 2013. As the main theme of the conference was Tafsiri ‘Translations’, an analysis of Euphrase Kezilahabi’s poetry will be present-ed, with particular focus on the limits of both language and translation. Looking at the linguistic prop-erties of Kezilahabi’s poetry these linguistic limits seem to represent the various stages of his philoso-phy; in this journey language is the means and the goal itself as it is an important unit of existence. Kezilahabi transfers many ´African´and Swahili elements from past to present and he transfers for-eign elements, from outside to inside, written anew and revived through the poet’s words. This analysis will consider the poetic word as a result of this comparison. The poetic of Euphrase Kezilahabi is also an original result of a comparison between his culture and literature and foreign literature.
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Elvidge, Charlotte E. S. "“Time is a wall”: a spectrum representation of traditions and modernities." Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-107456.

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This paper looks at traditions and modernities in terms of a spectrum representation and thus challenges the previously accepted notion of tradition and modernity as an either/or matter where tradition is seen to hold obstacles assumed to block progression towards modernity. With this in mind, it considers Ebrahim Hussein´s title for his play Wakati Ukuta (Time is a Wall) and Euphrase Kezilahabi´s novel Gamba la Nyoka (The snake´s skin) to illustrate the idea of multiple modernities where the relationship between tradition and modernity is seen in terms of tension between cultural homogenisation and cultural heterogenisation where various ´scapes´ containing traditions are inflected by historical, linguistic and political situatedness of different actors. Key themes are discussed in this paper displaying the indigenised ethnoscape of East Africa with various modernities and the different tensions this can produce in view of long-standing traditions. Individualism is the prevailing theme in the emergence of modernity. With this in mind, extramarital relationships, foreign behaviours, education and age/generational differences are discussed with reference to the two literary texts. These themes exemplify the thematic trajectory of the spectrum representation of traditions and modernities in Swahili literature, showing belonging to the present but also awareness of the past. This paper concludes that modernities should no longer be seen as a foreign invasion aiming to eradicate tradition but as metropolises that can be indigenised and incorporated into existing traditions. The observations in this paper demonstrate that the link between traditions and modernities is not a direct transition from one to the other but one of more complex affiliation. This paper lays foundations for broader research into this relationship and gives new insight into the illustration and critique of various texts.
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Books on the topic "Wakayin"

1

Chūsei wakaron. Tōkyō: Kasama Shoin, 2003.

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Kei, Hasegawa, ed. Wakaki tsumatachi. Tōkyō: Yumani Shobō, 2000.

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Shōtarō, Ikenami. Wakaki shishi. Tōkyō: Kōdansha, 2007.

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Heian jidai kōki wakaron. Tōkyō: Kazama shobō, 2000.

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Hiroyuki, Itsuki. Wakaki tomo yo: Wakai yūjin e no 28-tsū no tegami = Twenty-eight letters to young friends. Tōkyō: Gentōsha, 1995.

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Mohamed, Said Ahmed. Amri ya wakati. Nairobi: Oxford University Press, 2011.

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Nganwa, Kesi K. Emitwarize ya wakami. Kampala: Fountain Publishers, 2011.

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Yumie, Hiraiwa. Wakai shinju. Tōkyō: Bungei Shunjū, 2001.

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Wakaki hi no memori. Tōkyō: Bungeisha, 2015.

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Takenaga, Yoshimasa. Wakaki hi no Sōseki. Tōkyō: Yūbun Shoin, 1992.

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Book chapters on the topic "Wakayin"

1

Árokay, Judit. "Wakan rōeishū." In Kindlers Literatur Lexikon (KLL), 1–2. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_21262-1.

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Osman, Malam Bello. "Wakan Sule." In Voices of Ghana, 148. Boydell & Brewer, 2018. http://dx.doi.org/10.2307/j.ctvbtzpxc.34.

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Osman, Malam Bello. "Wakan Sule (A Song for a Shilling)." In Voices of Ghana, 148. Boydell and Brewer Limited, 2018. http://dx.doi.org/10.1017/9781787443457.031.

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"Materials for Nonlinear Optics: Toshihiro Arai (deceased) and Moriaki Wakaki." In Optical Materials and Applications, 107–32. CRC Press, 2017. http://dx.doi.org/10.1201/b12496-3.

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Naepels, Michel. "Violence segmentaire et construction de l’État postcolonial. Conflictualité et historicité à Wakaya (Houaïlou, Nouvelle-Calédonie)." In Sociétés en guerres, 113–27. Éditions de la Maison des sciences de l’homme, 2012. http://dx.doi.org/10.4000/books.editionsmsh.14673.

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"Chapter Six. Wakan in Literary Theory in the Fourteenth and Fifteenth Centuries: Zeami, Shōtetsu, Shinkei and Sōgi." In The Fracture of Meaning, 158–84. Princeton University Press, 1986. http://dx.doi.org/10.1515/9781400886029-010.

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"Chapter Five. Wakan and the Development of Renga Theory in the Late Fourteenth Century: Gido Shushin and Nijo Yoshimoto." In The Fracture of Meaning, 134–57. Princeton University Press, 1986. http://dx.doi.org/10.1515/9781400886029-009.

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"CAPÍTULO 7: Sacrificio de una alpaca en la cumbre de una montaña sagrada: el triple ritual del Wakan Wañu." In Religión, ritual y vida cotidiana en los Andes, 483–598. Vervuert Verlagsgesellschaft, 2003. http://dx.doi.org/10.31819/9783964565181-014.

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