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Journal articles on the topic 'Wallis et Futuna'
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1
MAYER, Raymond. "Les Cahiers de Wallis-et-Futuna." Journal de la société des océanistes, no. 126-127 (December 15, 2008): 341–43. http://dx.doi.org/10.4000/jso.2092.
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Riou, Olivier, Franck Ly, Marc Pracht, Nadia Leboulanger, Erwan Flecher, and Christophe Filande. "Médecine et santé à Wallis et à Futuna." La Presse Médicale Formation 1, no. 1 (March 2020): 82–88. http://dx.doi.org/10.1016/j.lpmfor.2020.03.007.
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Leleivai, Hapakuke Pierre. "Communication, politique et trajectoires identitaires à Wallis et Futuna." Hermès 32-33, no. 1 (2002): 181. http://dx.doi.org/10.4267/2042/14372.
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Capecchi, Bernard. "Les conséquences de l'instabilité tectonique à Wallis et Futuna." Cahiers d'outre-mer 48, no. 191 (1995): 381–400. http://dx.doi.org/10.3406/caoum.1995.3569.
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Badré, F., and M. Hoff. "Les Ptéridophytes des Iles Wallis et Futuna (Pacifique Sud) écologie et répartition." Feddes Repertorium 106, no. 3-4 (October 1995): 271–90. http://dx.doi.org/10.1002/fedr.4921060321.
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Badré, F., and M. Hoff. "Les Ptéridophytes des Iles Wallis et Futuna (Pacifique Sud) écologie et répartition." Feddes Repertorium 106, no. 3-4 (April 18, 2008): 271–90. http://dx.doi.org/10.1002/fedr.19951060321.
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Soulé, Marc. "Relations coutume, État, Église à Wallis et Futuna 1837-1961." Outre-mers 92, no. 348 (2005): 117–25. http://dx.doi.org/10.3406/outre.2005.4164.
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Douaire‑Marsaudon, Françoise. "Droit coutumier et loi républicaine dans une collectivité d’outre‑mer française (Wallis‑et‑Futuna)." Ethnologie française 169, no. 1 (2018): 81. http://dx.doi.org/10.3917/ethn.181.0081.
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De Forges, B. Richer. "Nouvelles Récoltes Et Nouvelles Espèces De Majidae De Profondeur Du Genre Oxypleurodon Miers, 1886." Crustaceana 68, no. 1 (1995): 43–60. http://dx.doi.org/10.1163/156854095x00377.
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AbstractMajid crabs of the genus Oxypleurodon from Indonesia, New Caledonia and Wallis and Futuna Islands, are studied here and their morphological characteristics precised. The position of this recently rehabilitated genus in relation to the two most closely similar genera Sphenocarcinus A. Milne Edwards, 1878 and Rochinia A. Milne Edwards, 1875, can now be reexamined. Two new species are described, O. tavaresi sp. nov. from Wallis Is., and O. karubar sp. nov. from the Moluccas.
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Rensch, Karl H. "The Delayed Impact." Language Problems and Language Planning 14, no. 3 (January 1, 1990): 224–36. http://dx.doi.org/10.1075/lplp.14.3.03ren.
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SOMMAIRE Effets tardifs: problèmes linguistiques de la période post-coloniale dans le territoire d'outre-mer français de Wallis et Futuna Contrairement à la plupart des langues du Pacifique qui ont été exposées à une influence croissante de l'anglais ou du français depuis l'arrivée des Européens dans cette région les langues des îles Wallis et Futuna sont restées relativement protégées des conséquences linguistiques du colonialisme du 19ième siècle. Ce n'est qu'après la deuxième guerre mondiale que la situation commença à changer. Alors deux événements les confrontèrent avec les mêmes problèmes sociolinguistiques que les autres îles du Pacifique avaient connus depuis des décennies, à savoir l'immigration d'un grand nombre de Wallisiens et Futuniens en Calédonie dans les années 50 et le changement du statut de protectorat en territoire en 1961. RESUMO Prokrastita kunpuŝiĝo: Postkoloniaj lingvaj problemoj en la franca transmara teritorio Valiso kaj Futuno (Centra Polinezio) Dum la plejparto de la pacifikaj lingvoj malfermiĝis al kreskanta influo de la angla kaj franca jam de la plej fruaj tagoj de kontakto, la teritorio Valiso kaj Futuno restis apenaŭ influita de la lingvaj konsekvencoj de la koloniismo de la 19-a jarcento. Du grandaj okazaĵoj - amasa migrado al Nova Kaledonio en la 1950-aj jaroj kaj transiro el la statuso de protektejo al tiu de franca transmara teritorio en 1961 - metis antaŭ la teritorion la samajn socilingvistikajn problemojn, kiuj jam de jardekoj ĉirkaŭas aliajn pacifikajn insulojn.
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Cabioch, Guy, Stéphane Calmant, Robert Pillet, Bernard Pelletier, Marc Régnier, and Pierre Lebellegard. "Apports de la croissance des coraux à l'étude sismo-tectonique de Futuna (territoire de Wallis et Futuna, Pacifique Sud-Ouest)." Comptes Rendus de l'Académie des Sciences - Series IIA - Earth and Planetary Science 329, no. 6 (September 1999): 429–34. http://dx.doi.org/10.1016/s1251-8050(00)80067-1.
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MAYER, Raymond. "Le classement des archives administratives de Wallis-et-Futuna (1951-2000) de Gildas Pressensé." Journal de la société des océanistes, no. 129 (December 15, 2009): 305–22. http://dx.doi.org/10.4000/jso.5968.
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Naepels, Michel. "Françoise Douaire-Marsaudon, Les Premiers fruits. Parenté, identité sexuelle et pouvoirs en Polynésie occidentale (Tonga, Wallis et Futuna)." L'Homme, no. 160 (January 1, 2001): 283–85. http://dx.doi.org/10.4000/lhomme.7947.
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Angleviel, Frédéric. "Wallis-et-Futuna (1942-1961) ou comment le fait migratoire transforma le protectorat en TOM." Journal de la société des océanistes, no. 122-123 (December 1, 2006): 61–76. http://dx.doi.org/10.4000/jso.541.
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Blanchet, Gilles. "Bilan de la mise en valeur des ressources de la mer à Wallis-et-Futuna." Journal de la société des océanistes, no. 122-123 (December 1, 2006): 110–21. http://dx.doi.org/10.4000/jso.579.
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Riou, Olivier. "La COVID à Wallis et Futuna, illusion dorée ? (Covid-19, Journal de bord, 17/08/2021)." La Presse Médicale Formation 2, no. 3 (August 2021): 215–16. http://dx.doi.org/10.1016/j.lpmfor.2021.08.001.
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André, Sylvie. "L'Union Europeenne et la Zeon du Pacifique." Victoria University of Wellington Law Review 28, no. 3 (June 1, 1998): 595. http://dx.doi.org/10.26686/vuwlr.v28i3.6069.
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L'Union européenne est présente, sous des formes diverses, dans la région Pacifique. Au-delà du cadre de sa politique commerciale extérieure, elle a des accords d'association avec un certain nombre de territoires insulaires. Ainsi, parmi les 20 pays et territoires d'outre-mer (PTOM) énumérés dans l'annexe I de la décision 91/482/CEE du Conseil du 25 juillet 1991, relative à l'association des pays et territoires d'outre-mer à la Communauté économique européenne , cinq sont situés dans la zone Pacifique : quatre territoires français, Polynésie française, Nouvelle Calédonie et ses dépendances, îles Wallis et Futuna, terres australes et antarctiques françaises et une colonie britannique, Pitcairn. Huit pays ACP ("Afrique, Caraïbes, Pacifique") appartiennent à la même zone géographique: Fidji, Kiribati, Papouasie Nouvelle Guinée, îles Salomon, Samoa occidentales, Tonga, Tuvalu, Vanuatu. Ces pays ont donc noué des relations d'association avec l'Union européenne dans le cadre des conventions de Lomé.
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Angelo, A. H. "Coutume Autochtone et Evolution du droit dans le Pacificque Sud." Victoria University of Wellington Law Review 26, no. 2 (May 1, 1996): 413. http://dx.doi.org/10.26686/vuwlr.v26i2.6175.
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This article is a book review of Paul de Deckker Coutume Autochtone et Evolution du droit dans le Pacficique Sud (1st ed, L'Harmattan, Paris, 1995) 304pp. The book is the product of a colloquium on indigenous custom and the development of law in the South Pacific, held in New Caledonia in July 1994. The papers from the colloquium provide a commentary and resource book on customary law in the South Pacific, with particular reference to the French territories of French Polynesia, New Caledonia, and Wallis and Futuna. Angelo argues that the book is good for reading, as an educational resource, and as stimulus to thought on the complex issues of the day. It is concluded that the book is an important contribution to the literature on the subject of law and custom, and presents in an accessible French much data not available elsewhere.
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Regnault, Jean-Marc. "La France Libre, Vichy et les Américains : Des relations difficiles dans le Pacifique en guerre. L'exemple des îles Wallis et Futuna (1940-1942)." Outre-mers 91, no. 344 (2004): 181–200. http://dx.doi.org/10.3406/outre.2004.4118.
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Sand, Christophe. "La datation du premier peuplement de Wallis et Futuna : contribution à la définition de la chronologie Lapita en Polynésie occidentale." Journal de la Société des océanistes 111, no. 2 (2000): 165–72. http://dx.doi.org/10.3406/jso.2000.2132.
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Yésou, Hervé, Pierre Chastanet, Jérôme Maxant, Claire Huber, Stephen Clandillon, Stéphanie Battiston, Catherine Proy, and Paul De Fraipont. "Contribution de l'imagerie Pléiades à la cartographie rapide des dégâts suite à des catastrophes majeures: retours d'expériences après deux ans d'actions de cartographie rapide localisées en Asie, en Afrique, en Europe et aux Caraïbes." Revue Française de Photogrammétrie et de Télédétection, no. 209 (January 29, 2015): 81–87. http://dx.doi.org/10.52638/rfpt.2015.236.
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Le lancement des deux satellites Pléiades 1A et 1B fin 2011 et 2012 a permis à la France de se doter de nouvelles capacités d'acquisition d'images optiques à très haute résolution, dans le domaine particulier de la gestion des crises mais aussi plus largement dans différentes thématiques d'Observation de la Terre. Les capacités et spécificités techniques de la Constellation Pléiades ouvrent de réelles opportunités pour la cartographie des dégâts suite à une catastrophe. Depuis 2012, le CNES, Airbus Defence and Space Geo-Intelligence et le SERTIT, ont combiné leurs efforts à plusieurs reprises pour assister les acteurs internationaux de la gestion de crise, optimisant les programmations des satellites Pléiades et analysant les images acquises. Différentes actions de cartographie réactive ont ainsi été menées, exploitant le potentiel de la Constellation Pléiades: inondations à Krymsk en Russie (07-2012), tremblement de terre dans la province iranienne d'Azerbaïdjan oriental (08-2012), inondations au Niger (08-2012), cyclone Sandy en Haïti (11-2012), typhon Bopha aux Philippines (12-2012), cyclone Evan à Wallis et Futuna (12-2012), cyclone Haruna à Madagascar (02-2013), inondations au Sénégal (08-2013), le cyclone Bejisa sur l'île de la Réunion (01-2014). Les premiers retours d'expérience sont plus que positifs, démontrant que les le système Pléiades est particulièrement adapté à la gestion de crise dans sa phase d'urgence. La très haute résolution spatiale permet une cartographie précise essentielle dans les zones critiques telles que les paysages urbains ou les infrastructures sensibles, la possibilité d'acquisition journalière et la livraison rapide des données constituent des atouts majeurs pour les applications spatiales, notamment pour la gestion des risques.
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Orpin, A. R., G. J. Rickard, P. K. Gerring, and G. Lamarche. "Tsunami hazard potential for the equatorial southwestern Pacific atolls of Tokelau from scenario-based simulations." Natural Hazards and Earth System Sciences Discussions 3, no. 7 (July 30, 2015): 4391–433. http://dx.doi.org/10.5194/nhessd-3-4391-2015.
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Abstract. Devastating tsunami over the last decade have significantly heightened awareness of the potential consequences and vulnerability to tsunami for low-lying Pacific islands and coastal regions. Our tsunami risk assessment for the atolls of the Tokelau Islands was based on a tsunami source–propagation–inundation model using Gerris Flow Solver, adapted from the companion study by Lamarche et al. (2015) for the islands of Wallis and Futuna. We assess whether there is potential for tsunami flooding on any of the village islets from a series of fourteen earthquake-source experiments that apply a combination of well-established fault parameters to represent plausible "high-risk scenarios" for each of the tsunamigenic sources. Earthquake source location and moment magnitude were related to tsunami wave heights and tsunami flood depths simulated for each of the three atolls of Tokelau. This approach was adopted to yield indicative and instructive results for a community advisory, rather than being fully deterministic. Results from our modelling show that wave fields are channelled by the bathymetry of the Pacific basin in such a way that the swathes of the highest waves sweep immediately northeast of the Tokelau Islands. From our series of limited simulations a great earthquake from the Kuril Trench poses the most significant inundation threat to Tokelau, with maximum modelled-wave heights in excess of 1 m, which may last a few hours and include several wave trains. Other sources can impact specific sectors of the atolls, particularly from regional sources to the south, and northern and eastern distant sources that generate trans-Pacific tsunami. In many cases impacts are dependent on the wave orientation and direct exposure to the oncoming tsunami. This study shows that dry areas remain around the villages in nearly all our "worst-case" tsunami simulations of the Tokelau Islands. Consistent with the oral history of little or no perceived tsunami threat, simulations from the recent Tohoku and Chile earthquake sources suggest only limited flooding. Where potential tsunami flooding was inferred from the modelling, recommended minimum evacuation heights above local sea level were compiled, with particular attention paid to variations in tsunami flood depth, subdivided into directional quadrants around each atoll. But complex wave behaviours around the atolls, islets, tidal channels and lagoons were also observed in our simulations. Wave amplitudes within the lagoons may exceed 50 cm, increasing any inundation and risks on the inner shoreline of the atolls, which may influence evacuation strategies. Our study shows that indicative, but instructive, simulation studies can be achieved even with only basic field information, due in part to the relative simplicity of the atoll topography and bathymetry.
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Orpin, Alan R., Graham J. Rickard, Peter K. Gerring, and Geoffroy Lamarche. "Tsunami hazard potential for the equatorial southwestern Pacific atolls of Tokelau from scenario-based simulations." Natural Hazards and Earth System Sciences 16, no. 5 (May 31, 2016): 1239–57. http://dx.doi.org/10.5194/nhess-16-1239-2016.
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Abstract. Devastating tsunami over the last decade have significantly heightened awareness of the potential consequences and vulnerability of low-lying Pacific islands and coastal regions. Our appraisal of the potential tsunami hazard for the atolls of the Tokelau Islands is based on a tsunami source–propagation–inundation model using Gerris Flow Solver, adapted from the companion study by Lamarche et al. (2015) for the islands of Wallis and Futuna. We assess whether there is potential for tsunami flooding on any of the village islets from a selection of 14 earthquake-source experiments. These earthquake sources are primarily based on the largest Pacific earthquakes of Mw ≥ 8.1 since 1950 and other large credible sources of tsunami that may impact Tokelau. Earthquake-source location and moment magnitude are related to tsunami-wave amplitudes and tsunami flood depths simulated for each of the three atolls of Tokelau. This approach yields instructive results for a community advisory but is not intended to be fully deterministic. Rather, the underlying aim is to identify credible sources that present the greatest potential to trigger an emergency response. Results from our modelling show that wave fields are channelled by the bathymetry of the Pacific basin in such a way that the swathes of the highest waves sweep immediately northeast of the Tokelau Islands. Our limited simulations suggest that trans-Pacific tsunami from distant earthquake sources to the north of Tokelau pose the most significant inundation threat. In particular, our assumed worst-case scenario for the Kuril Trench generated maximum modelled-wave amplitudes in excess of 1 m, which may last a few hours and include several wave trains. Other sources can impact specific sectors of the atolls, particularly distant earthquakes from Chile and Peru, and regional earthquake sources to the south. Flooding is dependent on the wave orientation and direct alignment to the incoming tsunami. Our "worst-case" tsunami simulations of the Tokelau Islands suggest that dry areas remain around the villages, which are typically built on a high islet. Consistent with the oral history of little or no perceived tsunami threat, simulations from the recent Tohoku and Chile earthquake sources suggest only limited flooding around low-lying islets of the atoll. Where potential tsunami flooding is inferred from the modelling, recommended minimum evacuation heights above local sea level are compiled, with particular attention paid to variations in tsunami flood depth around the atolls, subdivided into directional quadrants around each atoll. However, complex wave behaviours around the atolls, islets, tidal channels and within the lagoons are also observed in our simulations. Wave amplitudes within the lagoons may exceed 50 cm, increasing any inundation and potential hazards on the inner shoreline of the atolls, which in turn may influence evacuation strategies. Our study shows that indicative simulation studies can be achieved even with only basic field information. In part, this is due to the spatially and vertically limited topography of the atoll, short reef flat and steep seaward bathymetry, and the simple depth profile of the lagoon bathymetry.
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Behrend, Tim, Nancy K. Florida, Harold Brookfield, Judith M. Heimann, Harold Brookfield, Victor T. King, J. G. Casparis, et al. "Book Reviews." Bijdragen tot de taal-, land- en volkenkunde / Journal of the Humanities and Social Sciences of Southeast Asia 156, no. 4 (2000): 807–68. http://dx.doi.org/10.1163/22134379-90003831.
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- Tim Behrend, Nancy K. Florida, Javanese literature in Surakarta manuscripts; Volume 2; Manuscripts of the Mangkunagaran palace. Ithaca, New York: Cornell University Southeast Asia Program, 2000, 575 pp. - Harold Brookfield, Judith M. Heimann, The most offending soul alive; Tom Harrisson and his remarkable life. Honolulu: University of Hawai’i Press, 1998, 468 pp. - Harold Brookfield, Victor T. King, Rural development and social science research; Case studies from Borneo. Phillips, Maine: Borneo Research Council, 1999, xiii + 359 pp. [Borneo Research Council Proceedings Series 6.] - J.G. de Casparis, Roy E. Jordaan, The Sailendras in Central Javanese history; A survey of research from 1950 to 1999. Yogyakarta: Penerbitan Universitas Sanata Dharma, 1999, iv + 108 pp. - H.J.M. Claessen, Francoise Douaire-Marsaudon, Les premiers fruits; Parenté, identité sexuelle et pouvoirs en Polynésie occidentale (Tonga, Wallis et Futuna). Paris: Éditions de la Maison des Sciences de l’Homme, 1998, x + 338 pp. - Matthew Isaac Cohen, Andrew Beatty, Varieties of Javanese religion; An anthropological account. Cambridge: Cambridge University Press, 1999, xv + 272 pp. [Cambridge Studies in Social and Cultural Anthropology 111.] - Matthew Isaac Cohen, Sylvia Tiwon, Breaking the spell; Colonialism and literary renaissance in Indonesia. Leiden: Department of Languages and Cultures of Southeast Asia and Oceania, University of Leiden, 1999, vi + 235 pp. [Semaian 18.] - Freek Colombijn, Victor T. King, Anthropology and development in South-East Asia; Theory and practice. Kuala Lumpur: Oxford University Press, 1999, xx + 308 pp. - Bernhard Dahm, Cive J. Christie, A modern history of South-East Asia; Decolonization, nationalism and seperatism. London: Tauris, 1996, x + 286 pp. - J. van Goor, Leonard Blussé, Pilgrims to the past; Private conversations with historians of European expansion. Leiden: Research School CNWS, 1996, 339 pp., Frans-Paul van der Putten, Hans Vogel (eds.) - David Henley, Robert W. Hefner, Market cultures; Society and morality in the new Asian capitalisms. Boulder, Colorado: Westview Press, 1998, viii + 328 pp. - David Henley, James F. Warren, The Sulu zone; The world capitalist economy and the historical imagination. Amsterdam: VU University Press for the Centre for Asian Studies, Amsterdam (CASA), 1998, 71 pp. [Comparative Asian Studies 20.] - Huub de Jonge, Laurence Husson, La migration maduraise vers l’Est de Java; ‘Manger le vent ou gratter la terre’? Paris: L’Harmattan/Association Archipel, 1995, 414 pp. [Cahier d’Archipel 26.] - Nico Kaptein, Mark R. Woodward, Toward a new paradigm; Recent developments in Indonesian Islamic thought. Tempe: Arizona State University, Program for Southeast Asian Studies, 1996, x + 380 pp. - Catharina van Klinken, Gunter Senft, Referring to space; Studies in Austronesian and Papuan languages. Oxford: Clarendon Press, 1997, xi + 324 pp. - W. Mahdi, J.G. de Casparis, Sanskrit loan-words in Indonesian; An annotated check-list of words from Sanskrit in Indonesian and Traditional Malay. Jakarta: Badan Penyelenggara Seri NUSA, Universitas Katolik Indonesia Atma Jaya, 1997, viii + 59 pp. [NUSA Linguistic Studies of Indonesian and Other Languages in Indonesia 41.] - Henk Maier, David Smyth, The canon in Southeast Asian literatures; Literatures of Burma, Cambodia, Indonesia, Laos, Malaysia, the Philippines, Thailand and Vietnam. Richmond: Curzon, 2000, x + 273 pp. - Toon van Meijl, Robert J. Foster, Social reproduction and history in Melanesia; Mortuary ritual, gift exchange, and custom in the Tanga islands. Cambridge: Cambridge University Press, 1995, xxii + 288 pp. - J.A. de Moor, Douglas Kammen, A tour of duty; Changing patterns of military politics in Indonesia in the 1990’s. Ithaca, New York: Southeast Asia Program, Cornell University, 1999, 98 pp., Siddharth Chandra (eds.) - Joke van Reenen, Audrey Kahin, Rebellion to integration; West Sumatra and the Indonesian polity, 1926-1998. Amsterdam University Press, 1999, 368 pp. - Heather Sutherland, Craig J. Reynolds, Southeast Asian Studies: Reorientations. Ithaca: Southeast Asia Program, Cornell University, 1998, 70 pp. [The Frank H. Golay Memorial Lectures 2 and 3.], Ruth McVey (eds.) - Nicholas Tarling, Patrick Tuck, The French wolf and the Siamese lamb; The French threat to Siamese independence, 1858-1907. Bangkok: White Lotus, 1995, xviii + 434 pp. [Studies in Southeast Asian History 1.] - B.J. Terwiel, Andreas Sturm, Die Handels- und Agrarpolitik Thailands von 1767 bis 1932. Passau: Universität Passau, Lehrstuhl für Südostasienkunde, 1997, vii + 181 pp. [Passauer Beiträge zur Südostasienkunde 2.] - René S. Wassing, Koos van Brakel, A passion for Indonesian art; The Georg Tillmann collection at the Tropenmuseum Amsterdam. Amsterdam. Royal Tropical Institute/Tropenmuseum, 1996, 128 pp., David van Duuren, Itie van Hout (eds.) - Edwin Wieringa, J. de Bruin, Een Leidse vriendschap; De briefwisseling tussen Herman Bavinck en Christiaan Snouck Hurgronje, 1875-1921. Baarn: Ten Have, 1999, 192 pp. [Passage 11.], G. Harinck (eds.)
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Pollard, Kellie, Claire Smith, Jasmine Willika, Vince Copley sr, Vincent Copley jr, Christopher Willson, Emily Poelina-Hunter, and Julie Ah Quee. "Indigenous views on the future of public archaeology in Australia." AP: Online Journal in Public Archaeology 10 (March 21, 2021): 31. http://dx.doi.org/10.23914/ap.v10i0.293.
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This paper was written in response to a request by the editors of the AP: Online Journal of Public Archaeology, Jaime Almansa Sánchez and Elena Papagiannopoulou, for Claire Smith to write on the future of public archaeology in Australia. In Australia, public archaeology focusses on high profile colonial sites such as The Rocks in Sydney (Karskens 1999) and Port Arthur in Tasmania (Steele et al. 2007; Frew 2012), tourism (e.g. Cole and Wallis 2019) or enhancing school curricula (Nichols et al. 2005; Owens and Steele 2005). However, given her decades-long relationships with Jawoyn and Ngadjuri people (Smith 1999; Smith et al. 2016; Smith et al. 2020), Claire Smith decided that a useful way of approaching this topic would be to obtain Indigenous views on the subject. Accordingly, she contacted the Aboriginal co-authors of this article and invited them to co-author the paper. The possibility to write in free form was a boon. The ‘conversation’ format we settled on was designed to facilitate the voices of individuals, to present a range of Indigenous views, to allow people to express their views frankly, and to deal with the constraints of people being located in different parts of Australia as well as occasional lock-downs due to COVID-19. We decided on five topics/questions that would be the basis of the conversation. Each Aboriginal author gave their views either by email or by phone. These views were interwoven into a ‘conversation’. The language has been edited lightly for clarity and to simulate a real-life conversation. The final text was approved by all authors.
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Shaw, Paula, Pauline Green, Marlies Gration, Christine Rhodes, David Sheffield, and Julie Stone. "Within these hyperporous walls: An examination of a rebundled online learning model of higher education." Australasian Journal of Educational Technology 36, no. 5 (October 30, 2020): 85–101. http://dx.doi.org/10.14742/ajet.6061.
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Through this paper, we explore unbundling, the separation of various aspects of education, resources, teaching and assessment (Ossiannilsson et al., 2015) and rebundling, where these activities are “recombined into new configurations with little loss of functionality” (Ge et al., 2004, p. 1). We chart the evolution of online learning at the University of Derby, from a small-scale learning and certification bundle to a rebundled online university experience. In this rebundled model, a bespoke department is responsible for the operationalisation and quality of the university’s online experience. Firstly, we established the quality impact of this model, using higher education institution (HEI) value drivers. Secondly, focus groups explored macro (national), meso (institutional) and micro (practice) issues from strategic manager, academic and student experience perspectives. To facilitate discussion about the online university experience, we used a new conceptual pedagogic realignment with organisational priorities and horizon emergent technologies (PROPHET) framework. Based on our findings, we make recommendations to HEIs that are considering rebundling online learning. These include the equitable data capture and analysis of online student demographics; consideration of academic well-being and training; and the university-wide benefits obtained from knowledge exchange with online professionals, in relation to future-focused technologies and policymaking.
Implications for practice or policy:
HEIs should be equitable in their data capture and analysis processes, incorporating all online student and learner demographics.
HEIs should seek out and utilise the expertise of online professionals in institutional policymaking.
HEIs should refocus academic workload planning and training to include online learning.
HEIs should engage in evidence-based knowledge exchange with online professionals to ensure a future-focused cohesive university experience.
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O’brien, John T. "Commentary on: amnestic mild cognitive impairment and incident dementia and Alzheimer's disease in geriatric depression." International Psychogeriatrics 26, no. 12 (November 10, 2014): 2027–28. http://dx.doi.org/10.1017/s1041610214002087.
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In this month's “Paper of the Month,” Steffens and colleagues (Steffens et al., 2014) report on the relationship between depression, mild cognitive impairment (MCI) and future risk of progression to dementia. It has long been known that there is a complex relationship between depression and cognitive impairment, with depression common in those with cognitive impairment and dementia, and subsequent cognitive decline frequent in patients with depression (Wallin et al., 2013). This relationship has often been difficult to study, not least because definitions have often been mutually exclusive. For example, many studies of MCI have excluded patients with depression. This is not unreasonable to increase diagnostic certainty and obtain a more “pure” group of those with MCI who are likely to progress to Alzheimer's disease, but of course at the same time limits the ability to determine interactions between MCI and depression. On the other hand, it is known that non-cognitive symptoms, most particularly depression, frequently occur in those with MCI and have been shown to increase the risk of likely future decline.
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Vecenane, Helena, Dina Bethere, and Svetlana Usca. "THE PHYSICAL COMPETENCE OF FUTURE TEACHERS AS AN INPUT TOWARDS THE QUALITY OF THE PEDAGOGICAL ACTIVITY CONCEPT." SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference 1 (May 25, 2018): 570. http://dx.doi.org/10.17770/sie2018vol1.3335.
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The indicators of physical competence in scientific research studies and normative documents of education systems are defined differently. However, the consolidation of research evidence confirms that in this area the knowledge and skills of the person imply taking responsibility for health and well-being of one’s body, motoric skills, and ability to regulate and physically adapt to the surrounding environment. Undoubtedly, the family plays a major role in the development of children's physical competence. At the same time in this context the input of educational programmes is significant together with the individual physical competence of a teacher and his/her understanding about how to ensure its quality in one’s own work and in the concept of educational system.The aim of the research reflected in this publication is to analyse the physical competence of the students of Teacher Programmes as a resource for the development of the concept of their further pedagogical work. For this purpose, the emerging teachers have been surveyed using the methodology developed by Corbin et al. (2008). For statistical analysis of the research data the SPSS 22.0 programme was employed: a method of descriptive statistics, Kruskal-Wallis test, and Kendall's tau-b correlation test.
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Barat, Claire. "La ville de Sinope, réflexions historiques et archéologiques." Ancient Civilizations from Scythia to Siberia 16, no. 1-2 (2010): 25–536. http://dx.doi.org/10.1163/157005711x560309.
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Abstract The City of Sinope: Historical and Archaeological ReflectionsThis contribution concentrates on the city of Sinope in antiquity, on the urban morphology of a city constantly under occupation from the time of its founding in the 7th century BC. It starts out by presenting the city of Sinope through literary and numismatic sources and then provides an account of the excavations undertaken during the 20th century (the German-Turkish expedition under L. Budde and E. Akurgal in 1951-1953 and urban prospecting work by British Byzantinists A. Bryer and D. Winfled in the years 1960-1970). The third part of the article brings readers an idea of the archaeology of the city drawing on studies of the walls of Sinope, the urban organization of the city in antiquity and the ancient monuments still visible, such as the “Temple of Serapis” and the “Balat Kilise”. In conclusion new themes for future reflection are suggested such as the identification of the “Temple of Serapis” as a herôon and the location of an aqueduct at Sinope, which had still been visible at the beginning of the 20th century.
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Schuler, Kaitlyn R., Natasha Basu, Nicholas A. Fadoir, Laura Marie, and Phillip N. Smith. "Forms of suicide communication are not associated with five-factor personality." Journal of Aggression, Conflict and Peace Research 12, no. 2 (February 22, 2020): 45–54. http://dx.doi.org/10.1108/jacpr-12-2019-0465.
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Purpose US age-adjusted suicide rates increased by 33 per cent from 1999 to 2017 (Hedegard et al., 2018). Communications about suicide and death are a commonly cited warning sign (SPRC, 2014) and are foundational to the vast majority of risk assessment, prevention and intervention practices. Suicidal communications are critically understudied despite their implications for prevention and intervention practices. The purpose of this study is to examine the association between five factor model personality traits and forms of suicidal communications. Design/methodology/approach A sample of 154 people admitted to emergency psychiatry for suicide ideation or attempt completed self-report measures about their suicide ideation and behavior. Kruskal–Wallis ANOVA examined differences between five-factor model personality domains and forms of communications. Findings There were no significant differences; however, two nonsignificant trends related to indirect or non-communication and extraversion and openness emerged. Research limitations/implications Future studies should focus on using more nuanced measures of dimensional personality and suicidal communications. Originality/value This study is the first to examine differences in the Five-Factor Model personality traits and suicidal communications.
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Ongaki, Jacob. "An examination of the relationship between flexible work arrangements, work-family conflict, organizational commitment, and job performance." Management 23, no. 2 (December 1, 2019): 169–87. http://dx.doi.org/10.2478/manment-2019-0025.
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Summary Many employees are often faced with an inter-role conflict between work and that of a family in the U.S. However, business leaders and Human Resource Management (HRM) may not recognize the problem affecting white-collar employees. The purpose of this non-experimental quantitative study was to determine whether or not a relationship existed between employees’ use of flexible working arrangements as predictor variables (such as flexible work schedules and telecommuting) and work-family conflict and family-work conflict as covariate variables, and organizational outcomes (such as organizational commitment and job performance outcome variables). The self-reported survey data included 237 employees who have utilized flexible work arrangements in service organizations in the state of Texas. The inconclusive ANCOVA parametric data assumption resulted in further employ Kruskal-Wallis statistical analysis with less restrictive normality assumption The ANCOVA and Kruskal-Wallis analyses tests revealed a statistically significant result for employees’ use of flexible work options (a combination of flexible work schedules and telecommuting) to alleviate family-work conflict. The use of a single option (flexible work schedules or telecommuting) was statistically insignificant to employees. Despite the rigorous study, limitations are inevitable particularly for self-reported data and non-experimental study. The difficulty to determine the participants’ honesty unintentional misrepresentations reflected in the validity of the study (Hunter, 2012; Matsui et al., 2005). Nevertheless, the study provided insight information to organizational management not to overlook the use of flexible work arrangement practices to mitigate employees’ family-work conflict (Gözükara & Çolakoğlu, 2015) to achieve organizational outcomes. Future researchers should replicate this study to include flexible work arrangement users vs. non-flexible work arrangement employees in other states, regions, and industries.
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Garcia-Talegon, Jacinta, Adolfo C. Iñigo, Santiago Vicente-Tavera, and Eloy Molina-Ballesteros. "Heritage Stone 5. Silicified Granites (Bleeding Stone and Ochre Granite) as Global Heritage Stone Resources from Ávila, Central Spain." Geoscience Canada 43, no. 1 (March 14, 2016): 53. http://dx.doi.org/10.12789/geocanj.2016.43.087.
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Silicified granites were used to build the Romanesque monuments in the city of Ávila, Spain. The building stones comprise two types of granite based on their technical properties and colour: Bleeding Stone (Piedra Sangrante) and Ochre Granite (Caleño). They were used as a facing stone in the city´s Romanesque monuments of the 12th century (e.g. the cathedral and church of San Pedro), and the famous city walls that constitute the best example of military Romanesque Spanish architecture. During the Gothic and Renaissance periods of the 13th and 15th centuries, silicified granites were used mainly to build ribbed vaults, the voissoirs of the arches, and elements of the windows in the monuments of Ávila. Silicified granites are found in the intermediate and upper part of a complex palaeoweathering zone or mantle developed on the Iberian Hercynian Basement which underlies much of the western Iberian Peninsula. The silicification occurred during tropical conditions in the Mesozoic. The weathered mantle was truncated by Alpine tectonic movements during the Tertiary, and its remnants were unconformably overlain by more recent sediments in the western and southern part of the Duero Basin and along the northern edge of the Amblés Valley graben. The historical, and now protected, quarry is located in a village called La Colilla, about 5 km from the city of Ávila. Currently, this stone is exploited only for restoration work performed in the city, for example the Walls of Ávila, and the church of San Pedro. The resource is limited and being depleted, so the stone will be scarce in the near future. Consequently, these silicified granites should be recognized as a Global Heritage Stone Resource. The specific technical properties of these stones and their historic use, decay patterns, durability, and suitability for conservation treatments combine to support its designation as a Global Heritage Stone Resource.RÉSUMÉDes granites silicifiés ont été utilisés pour construire les monuments romans dans la ville d’Ávila, en Espagne. Les pierres de construction comprennent deux types de granite selon leurs propriétés techniques et leur couleur : Bleeding Stone (Piedra sangrante) et Ochre Granite (Caleño). Ils ont été utilisés comme pierre de revêtement de monuments romans du 12ème siècle de la ville (par exemple la cathédrale et de l'église de San Pedro), et pour les célèbres remparts de la ville qui constituent le meilleur exemple de l'architecture espagnole romane militaire. Durant les périodes gothique et Renaissance des 13e et 15e siècles, les granites silicifiés ont été utilisés principalement pour construire des croisés d'ogives, des voussoirs d’arcs et des éléments de fenêtres des monuments d’Ávila. Les granites silicifiés se trouvent dans la partie intermédiaire et supérieure d'une zone complexe de paléo-altération ou de manteau développée sur le socle ibérique hercynien qui supporte une grande partie de la péninsule ibérique occidentale. La silicification s’est produite dans des conditions tropicales au Mésozoïque. Le matériau mantélique altéré a été tronqué par des mouvements tectoniques alpins au cours du Tertiaire, et ses restes ont été recouverts en discordance par des sédiments plus récents dans la partie ouest et sud du bassin de Duero, et le long de la bordure nord de la vallée en graben d’Amblés. L’ancienne carrière, maintenant protégée, est située dans un village appelé La Colilla, à environ 5 km de la ville d’Ávila. Actuellement, cette pierre est exploitée uniquement pour les travaux de restauration effectués dans la ville, par exemple les murs d’Ávila, et l'église de San Pedro. La ressource est limitée et en voie d'épuisement, de sorte que la pierre sera rare dans un proche avenir. Par conséquent, ces granites silicifiés devraient être reconnus en tant que pierre du Patrimoine mondial des ressources en pierre. Les propriétés techniques spécifiques de ces pierres et leur valeur historique, leurs modes de désintégration, leur durabilité et leur pertinence pour la conservation patrimoniale justifient leur désignation en tant que roche du Patrimoine mondial des ressources en pierre. Traduit par le Traducteur
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Usca, Svetlana, Helēna Vecenāne, and Dina Bethere. "THE EMERGING TEACHERS’ COMPETENCE FOR IMPROVING HEALTHY LIFESTYLE AND FACTORS IMPACTING IT." CBU International Conference Proceedings 6 (September 27, 2018): 816–21. http://dx.doi.org/10.12955/cbup.v6.1254.
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This publication analyses and discusses the aspects of healthy lifestyle implementation competence in the personal life of students and future teachers, viewing it as a potential contribution to their professional career. The correlation of internal factors such as students' attitudes, knowledge, skills and abilities and influence of external factors of social environment are analysed as healthy lifestyle competence. The empirical study focuses on two priority healthy lifestyle components –physical activity and the development of healthy eating habits in relation to the conditions provided by a higher education microsystem formulating a proposal for improving the interaction of these factors. For achieving the research goal, emerging teachers have been surveyed using the methodology developed by Corbin et al. (2008). For statistical analysis of the research data, the SPSS 22.0 program was employed: a method of descriptive statistics, Kruskal-Wallis test, and Kendall's tau-b correlation test. The results of this study prove the differences in competence indicators in relation to the respondents’ age and chosen specialization, as well as show the lack of support from professional management and medical staff for implementation of a healthy lifestyle.
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Goules, A., L. Chatzis, V. Pezoulas, C. Baldini, F. Skopouli, A. Venetsanopoulou, P. Voulgari, et al. "OP0291 SEVERITY OF LABIAL MINOR SALIVARY GLAND FOCUS SCORE AND FUTURE LYMPHOMA DEVELOPMENT IN SJÖGREN’S SYNDROME." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 178.2–179. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2539.
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Background:The typical histologic picture of focal sialadenitis in the labial minor salivary gland (LMSG) tissues has been incorporated as a parameter in the majority of Sjögren’s syndrome (SS) classification criteria, with focus score (FS) being the most widely used (1). In previous studies, higher FS has been associated with the presence of autoantibodies and extra-glandular manifestations including lymphoma, implying that FS can predict severe disease (2,3). However, there are no studies exploring the association of FS with lymphoma development along with the time interval from SS diagnosis to lymphoma diagnosis.Objectives:To investigate an association of focus score grading with lymphoma development and time to lymphoma occurrence.Methods:From a total population 1998 consecutive patients fulfilling the 2016 ACR-EULAR criteria for SS who were followed-up in 5 Rheumatology centers from Greece and Italy (Universities of Athens, Pisa, Udine, Harokopio and Ioannina) (UPAHI group), those with positive (LMSG) (FS ≥1) were identified. (1). Patients who had not been subjected to an LMSG biopsy or had a negative biopsy (FS<1) or the biopsy was evaluated using other histologic classifications were excluded from the present study. Lymphoma patients with diagnostic LMSG biopsy performed within a year from lymphoma diagnosis as well as non-lymphoma patients with less than 1 year between SS diagnosis and their last follow up, were also excluded. Cumulative clinical and histologic data attributed to SS as defined by ESSDAI and/or ESSPRI, up to lymphoma diagnosis or last follow up, were recorded. A combined data driven Fast Correlation Based Feature selection (FCBF)/Logistic Regression (LR) model was applied on the unified dataset to identify independent lymphoma associated risk factors. A correlation between FS and time interval until lymphoma diagnosis was performed using the Pearson formula.Results:A unified dataset of 618 SS patients with FS≥1 and at least one year of disease duration from SS diagnosis to lymphoma diagnosis or last follow up, with 30 clinical, laboratory and histologic features, was constructed. The median age at SS diagnosis was 53 (range: 15 – 80) years old, the female to male ratio was 20:1 and the median disease duration was 6 years (range: 1-35). Half (49%) of the study population had focus score between one and two (1≤FS<2), followed by a declining proportion of patients accounted for every subsequent escalating FS group. No statistically significant difference was found regarding disease duration among the various FS escalating groups (p= 0.1603, Kruskal-Wallis test). Fifty eight patients had lymphoma with no statistically significant difference in disease duration compared to non-lymphoma controls. The data driven FCBF/LR algorithm with lymphoma on the whole dataset revealed that cryoglobulinemia (p=0.021), salivary gland enlargement (p=0.008) and FS (p=0,049) are independent lymphoma associated risk factors. A statistically significant negative correlation was found using a Pearson formula (R=-0.32 and p=0.015) regarding the focus score and the time to lymphoma diagnosis.Conclusion:This is the largest study of SS patients’ histologic analysis exploring the association of LMSG FS grading with lymphoma development and the time interval until its diagnosis. Higher FS values correlate with increased lymphoma risk and early lymphoma occurrence.Figure 1.Pearson correlation between FS and time interval until lymphoma diagnosisReferences:[1]Shiboski et al. Arhtritis Rheumatol. 2017[2]Carrubi et al. Lupus 2015[3]Risselada AP et al. Ann Rheum Dis 2014Disclosure of Interests:None declared
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Ebaid, Abdelhalim, and Emad H. Aly. "Exact Analytical Solution of the Peristaltic Nanofluids Flow in an Asymmetric Channel with Flexible Walls and Slip Condition: Application to the Cancer Treatment." Computational and Mathematical Methods in Medicine 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/825376.
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In the cancer treatment, magnetic nanoparticles are injected into the blood vessel nearest to the cancer’s tissues. The dynamic of these nanoparticles occurs under the action of the peristaltic waves generated on the flexible walls of the blood vessel. Studying such nanofluid flow under this action is therefore useful in treating tissues of the cancer. In this paper, the mathematical model describing the slip peristaltic flow of nanofluid was analytically investigated. Exact expressions were deduced for the temperature distribution and nano-particle concentration. In addition, the effects of the slip, thermophoresis, and Brownian motion parameters on the temperature and nano-particle concentration profiles were discussed and further compared with other approximate results in the literatures. In particular, these results have been obtained at the same values of the physical examined parameters that was considered in Akbar et al., “Peristaltic flow of a nanofluid with slip effects,” 2012. The results reveal that remarkable differences are detected between the exact current results and those approximately obtained in the literatures for behaviour of the temperature profile and nano-particles concentration. Accordingly, the current analysis and results are considered as optimal and therefore may be taken as a base for any future comparisons.
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Thomas, Robert J., Alex McConnachie, Madeleine M. A. Williams, and Bethany Stanley. "Dietary intake of broccoli and the risk of cancer in the prostate, lung, colorectal, and ovarian cancer (PCLO) screening trial." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e13560-e13560. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e13560.
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e13560 Background: The cruciferous vegetable broccoli, are a good source of vitamins, minerals and fibre, as well as thiol phytochemicals (indole-3-carbinol), glucosinolates (isothiocyanates, its metabolite, sulforaphane), carotenoids (lutein and zeaxanthin) and flavonols (kaempferol). Laboratory and human biopsy studies have found that broccoli intake influenced epigenetic expression of genes via blockage of histone deacetylase which reduce inflammation and cancer growth. Clinically, a randomised control study reported dried broccoli extract (along with three other foods) influenced PSA progression in men with prostate cancer1. However, no preventative intervention studies in humans have been conducted and data from cohort studies are inconsistent for its influence on cancer incidence2,3. Methods: We analysed 49,104 people within the intervention arm of the 155,000 participant PLCO screening trial. Histological confirmed cases of any cancer were reported in 8,263 (16.83%) during the 11.5 year follow up. Broccoli consumption was assessed with a food frequency questionnaire (FFQ). Baseline characteristics were compared between broccoli consumption groups using Chi-square and Kruskal-Wallis tests. Cox regression models were used to assess the association between broccoli intake and cancer incidence. Results: Broccoli consumption was associated with reduced cancer incidence: HR 0.95 (CI 0.93-0.97, p < 0.001). This pattern persisted with adjustments for age, sex, race, education level and family history (HR 0.97, CI 0.96-0.99, p = 0.007) as well as smoking, BMI and alcohol consumption (HR 0.98, CI 0.96-0.99, p = 0.010). Conclusions: The study identified an association between increased broccoli consumption and reduced cancer risk. In practical terms, 15g of broccoli, or more, consumed per day (about a small cup) was associated with a 5% lower risk of cancer. Broccoli should continue to be included in healthy eating advice. This data supports the consideration of future prospective intervention studies investigating the role of broccoli as part of a cancer prevention programme. References 1. Thomas et al. The NCRN Pomi-T RCT. Prostate cancer & prostatic diseases (2014), 2,180. 2. Liu et al Cruciferous vegetables inversely linked with breast cancer: Breast (2013), 22;3,309. 3. Bosetti et al Cruciferous vegetables and cancer risk Ann Oncol (2012) 23(8);2198.
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Thomas, Robert J., Alex McConnachie, Bethany Stanley, and Madeleine Williams. "Dietary consumption of tea and the risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e13559-e13559. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e13559.
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e13559 Background: The popular beverage tea, brewed from infused leaves of camellia sinesis, contains non-phytoestrogenic polyphenols such as flavonoids, anthocyanidins, flavanols (epigallocatechin gallate); phenolic acids (ellagic acid) and stimulants (caffeine, theophylline). Laboratory studies report tea promotes antioxidant enzyme formation, slows cancer cell proliferation and unblocks apoptosis. Clinically, the Pomi-T randomised study reported tea extract (along with three other foods) reduced PSA progression in men with prostate cancer1. Evidence of prostate cancer prevention, however, from prospective cohort data is conflicting with one recent study even implying an increased risk2. Methods: We analysed 25,097 men within the intervention arm of the 155,000 participant PLCO screening trial. Histological confirmed cases of prostate cancer were reported in 3,088 men (12.3%) during the 11.5 year follow up. Tea consumption was assessed with a food frequency questionnaire (FFQ). Baseline characteristics were compared between groups using Chi-square and Kruskal-Wallis tests. Cox regression models were used to assess the association between tea intake and prostate cancer incidence. Results: Overall tea consumption was associated with a significantly lower risk of prostate cancer (p = 0.009). More precisely, the participants in the highest third of consumption group had a significantly lower risk compared to those in the lowest third (HR 1.16 (CI 1.05-1.29, p = 0.004). This pattern persisted with adjustments for age, sex, race and education level (p = 0.034), family history of cancer (p = 0.037). Those who never drank tea, however, had no statistical lower risk of prostate cancer compared to other groups (p = 0.501). Conclusions: Among tea drinkers, this data revealed a positive association between drinking tea and a reduced risk of prostate cancer. This data supports the consideration of future prospective intervention studies investigating the role of tea as part of a prostate cancer prevention programme. 1. Thomas et al. The NCRN Pomi-T RCT. Prostate cancer & prostatic diseases (2014), 2,180. 2. Reger et al. Dietary isoflavones and prostate cancer risk. Int J. Cancer (2017), 142; 4, 719.
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Escobar-López, Sttefanie Yenitza, Angélica Espinoza-Ortega, Carmen Lozano-Cabedo, Encarnación Aguilar-Criado, and Santiago Amaya-Corchuelo. "Motivations to consume ecological foods in alternative food networks (AFNs) in Southern Spain." British Food Journal 121, no. 11 (October 24, 2019): 2565–77. http://dx.doi.org/10.1108/bfj-01-2019-0051.
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Purpose The purpose of this paper is to identify the motivations to consume ecological foods in alternative food networks (AFNs). Design/methodology/approach In total, 150 questionnaires were applied; the questionnaire was adapted from Food Choice Questionnaire (Steptoe et al., 1995). Data were analyzed by means of multivariate statistics with factor and cluster analysis. In order to identify statistical differences (p<0.05), Kruskal–Wallis and Mann–Whitney nonparametric tests were performed. Findings Ten factors or motivations were found: social ecological concern, nutritional content, sensory aspects, certifications, naturalness, specialized consumption, trust in the seller, economic aspects, health and availability. Four groups were obtained and called: citizen consumers, in-process citizen consumers, conscious social consumers with no interest in certifications and conscious pragmatic consumers. It is concluded that differentiated consumers visit these establishments and their motivations are diverse, albeit they concur, to a varying extent, with the objectives of AFNs, finding a mixture of hedonic and ethical motivations. Practical implications This sort of works about specific places of consumption as well as specific consumers, in this case ecological, contributes to the development of future social research on other contexts, different consumers and products. Originality/value This sort of research has been carried out in various European cities, with a number of foods and over various sales channels; however, at present there is a debate around AFNs and the veracity of their goals. This way, the present work can contribute with an answer to whether the goals match the motivations of consumers.
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Komoriya, Kiyoshi. "Special Issue on Mobile Robot." Journal of Robotics and Mechatronics 11, no. 1 (February 20, 1999): 1. http://dx.doi.org/10.20965/jrm.1999.p0001.
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Mobility, or locomotion, is as important a function for robots as manipulation. A robot can enlarge its work space by locomotion. It can also recognize its environment well with its sensors by moving around and by observing its surroundings from various directions. Much researches has been done on mobile robots and the research appears to be mature. Research activity on robot mobility is still very active; for example, 22% of the sessions at ICRA'98 - the International Conference on Robotics and Automation - and 24% of the sessions at IROS'98 - the International Conference on Intelligent Robots and Systems - dealt with issues directly related to mobile robots. One of the main reasons may be that intelligent mobile robots are thought to be the closest position to autonomous robot applications. This special issue focuses on a variety of mobile robot research from mobile mechanisms, localization, and navigation to remote control through networks. The first paper, entitled ""Control of an Omnidirectional Vehicle with Multiple Modular Steerable Drive Wheels,"" by M. Hashimoto et al., deals with locomotion mechanisms. They propose an omnidirectional mobile mechanism consisting of modular steerable drive wheels. The omnidirectional function of mobile mechanisms will be an important part of the human-friendly robot in the near future to realize flexible movements in indoor environments. The next three papers focus on audiovisual sensing to localize and navigate a robot. The second paper, entitled ""High-Speed Measurement of Normal Wall Direction by Ultrasonic Sensor,"" by A. Ohya et al., proposes a method to measure the normal direction of walls by ultrasonic array sensor. The third paper, entitled ""Self-Position Detection System Using a Visual-Sensor for Mobile Robots,"" is written by T. Tanaka et al. In their method, the position of the robot is decided by measuring marks such as name plates and fire alarm lamps by visual sensor. In the fourth paper, entitled ""Development of Ultra-Wide-Angle Laser Range Sensor and Navigation of a Mobile Robot in a Corridor Environment,"" written by Y Ando et al., a very wide view-angle sensor is realized using 5 laser fan beam projectors and 3 CCD cameras. The next three papers discussing navigation problems. The fifth paper, entitled ""Autonomous Navigation of an Intelligent Vehicle Using 1-Dimensional Optical Flow,"" by M. Yamada and K. Nakazawa, discusses navigation based on visual feedback. In this work, navigation is realized by general and qualitative knowledge of the environment. The sixth paper, entitled ""Development of Sensor-Based Navigation for Mobile Robots Using Target Direction Sensor,"" by M. Yamamoto et al., proposes a new sensor-based navigation algorithm in an unknown obstacle environment. The seventh paper, entitled ""Navigation Based on Vision and DGPS Information for Mobile Robots,"" S. Kotani et al., describes a navigation system for an autonomous mobile robot in an outdoor environment. The unique point of their paper is the utilization of landmarks and a differential global positioning system to determine robot position and orientation. The last paper deals with the relationship between the mobile robot and computer networks. The paper, entitled ""Direct Mobile Robot Teleoperation via Internet,"" by K. Kawabata et al., proposes direct teleoperation of a mobile robot via the Internet. Such network-based robotics will be an important field in robotics application. We sincerely thank all of the contributors to this special issue for their cooperation from the planning stage to the review process. Many thanks also go to the reviewers for their excellent work. We will be most happy if this issue aids readers in understanding recent trends in mobile robot research and furthers interest in this research field.
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Sivarethinamohan, R., and S. Sujatha. "Ethical Living and Work Self Efficacy Beliefs of Academicians of Higher Education in ASIA: A Key Determinant of One's Belief in One's Ability to Achieve the Desired Result in a Precise State of Affairs." International Journal of Higher Education 8, no. 6 (October 23, 2019): 203. http://dx.doi.org/10.5430/ijhe.v8n6p203.
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Ethical academicians are perfectly virtuous. They always strive for greater virtue and follow strictly the moral stands of their profession. The ethical living and self-efficacy are important to them because of being fair and honest in their academics. Determinants of ethics include knowledge, values, attitude and intention. The domain-specific framework developed by Verbeke et al. (2004) has been considered as fundamental for identifying the dimensionality of work Self-efficacy and ethical challenges of academicians. A comprehensive literature review is undertaken regarding the concept of work Self-efficacy to assess workers' confidence and their ethical living in the workplace. This article examines theoretically and analytically the antecedent processes and information cues involved in the formation of work self-efficacy. Theoretical and numerical analysis of the key determinants of work self-efficacy increases the understanding of moral values, truthful fair and honest. Factors which decisively affect ethical living were identified from literature collected from the academicians who are working in the Five Regions of Asia - Central Asia (Tajikistan, Uzbekistan, Kazakhstan, Turkmenistan, Kyrgyzstan) East Asia (China, Mongolia, North Korea, South Korea, Japan, Hong Kong, Taiwan, Macau) South Asia (Sri Lanka, Bangladesh, India, Afghanistan, Pakistan, Bhutan, Nepal, the Maldives) through Google classroom. Methods of Statistical Analysis of self-efficacy data are descriptive statistics, Pearson Correlation Coefficient and Kolmogorov-Smirvnos normality test and Kruskal–Wallis one-way analysis of variance and Principal Component Analysis. Positive, mastery experiences give academicians a sense of accomplishment when they have faced a challenge ethically. Positive Zeal during Academic interaction, vicarious experiences that occur when academician see others succeed and feel an increased sense of their own ability to succeed. Sincere & deeper self, mingling with students, Social persuasion increase a teacher’s sense of confidence and ability to succeed. A proper plan of action has drawn special attention, and inferences pertaining to future research are discussed at the end of the critique.
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Ekanayake, Sanka Dilshan, D. S. Liyanapathirana, and Chin Jian Leo. "Numerical simulation of EPS geofoam behaviour in triaxial tests." Engineering Computations 32, no. 5 (July 6, 2015): 1372–90. http://dx.doi.org/10.1108/ec-12-2013-0300.
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Purpose – EPS geofoam has been widely used in embankment construction, slope stabilisation, retaining walls, bridge approaches and abutments. Nevertheless, the potential of EPS geofoam as an engineering material in geotechnical applications has not been fully realised yet. The purpose of this paper is to present the finite element formulation of a constitutive model based on the hardening plasticity, which has the ability to simulate short-term behaviour of EPS geofoam, to predict the mechanical behaviour of EPS geofoam and it is implemented in the finite element programme ABAQUS. Design/methodology/approach – Finite element formulation is presented based on the explicit integration scheme. Findings – The finite element formulation is verified using triaxial test data found in the literature (Wong and Leo, 2006 and Chun et al., 2004) for two varieties of EPS geofoam. Performance of the constitute model is compared with four other models found in the literature and results confirm that the constitutive model used in this study has the ability to simulate the short-term EPS geofoam behaviour with sufficient accuracy. Research limitations/implications – This research is focused only on the short-term behaviour of EPS geofoam. Experimental studies will be carried out in future to incorporate effects of temperature and creep on the material behaviour. Practical implications – This formulation will be applicable to finite element analysis of boundary value problems involving EPS geofoam (e.g. application of EPS geofoam in ground vibration isolation, retaining structures as compressible inclusions and stabilisation of slopes). Originality/value – Finite element analysis of EPS geofoam applications are available in the literature using elastic perfectly plastic constitutive models. However, this is the first paper presenting a finite element application utilising a constitutive model specifically developed for EPS geofoam.
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Ryan, Deirdre D., Alastair J. H. Clement, Nathan R. Jankowski, and Paolo Stocchi. "The last interglacial sea-level record of Aotearoa New Zealand." Earth System Science Data 13, no. 7 (July 14, 2021): 3399–437. http://dx.doi.org/10.5194/essd-13-3399-2021.
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Abstract. This paper presents the current state of knowledge of the Aotearoa New Zealand last interglacial (marine isotope stage 5, MIS 5, sensu lato) sea-level record compiled within the framework of the World Atlas of Last Interglacial Shorelines (WALIS) database. A total of 77 relative sea-level (RSL) indicators (direct, marine-limiting, and terrestrial-limiting points), commonly in association with marine terraces, were identified from over 120 studies reviewed. Extensive coastal deformation around New Zealand has prompted research focused on active tectonics, the scale of which overprints the sea-level record in most regions. The ranges of last interglacial palaeo-shoreline elevations are significant on both the North Island (276.8 ± 10.0 to −94.2 ± 10.6 ma.m.s.l., above mean sea level) and South Island (165.8 ± 2.0 to −70.0 ± 10.3 ma.m.s.l.) and have been used to estimate rates of vertical land movement; however, in many instances there is a lack of adequate description and age constraint for high-quality RSL indicators. Identified RSL indicators are correlated with MIS 5, MIS 5e, MIS 5c, and MIS 5a and indicate the potential for the New Zealand sea-level record to inform sea-level fluctuation and climatic change within MIS 5. The Northland Region of the North Island and southeastern South Island, historically considered stable, have the potential to provide a regional sea-level curve, minimally impacted by glacio- and hydro-isostatic adjustment (GIA) and reflecting near-eustatic fluctuations in a remote location of the South Pacific, across broad degrees of latitude; however, additional records from these regions are needed. Future work requires modern analogue information, heights above a defined sea-level datum, better stratigraphic descriptions, and use of improved geochronological methods. The database presented in this study is available open access at this link: https://doi.org/10.5281/zenodo.4590188 (Ryan et al., 2020a).
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Miller, Kelly LR, Heidar Albandar, David Key, and John J. Haluschak. "Standard of care for MIBC is becoming more standard." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): e16011-e16011. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e16011.
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e16011 Background: Despite consensus guideline recommendations, the management of muscle invasive bladder cancer (MIBC) varies dependent on institution setting. The risk of recurrence of localized bladder cancer after cystectomy is substantial and associated with stage. The current standard of care for possibly T2 and certainly T3-T4 MIBC is neoadjuvant cisplatin (NAC) based chemotherapy followed by cystectomy. As recent as 2011, only 12% of patients in this category actually received NAC (Feifer et al. 2011). Similar statistics have been confirmed in the US and Canada. Given there is a 13% reduction in risk of death with use of NAC, the adherence to this recommendation needs to improve. We hypothesize that in a multispecialty community practice where barriers to care are reduced that the percentage of eligible patients receiving NAC is significantly higher than previously reported. Methods: After IRB exemption obtained, patients from 2012-2015 with MIBC who underwent cystectomy were examined. Data collection included age, sex, date of consultation, dates and type of chemotherapy received, eGFR, date of surgery and surgical pathology report staging. Data were analyzed using Kolmogorov-Smirnov, Shapiro-Wilk, Mann-Whittney and Kruskal-Wallis statistical tests. Results: The average patient age was 69 years old with a male predominance. Approximately 54% of patients received neoadjuvant chemotherapy; however, three of those patients did not receive the recommended cisplatin based regimen. Fifty percent of patients received NAC and 57% of cisplatin eligible (age < 80, eGFR > 30) patients received NAC. The average time to cystectomy was 171 days among those receiving NAC, with a decrease in time to cystectomy correlating with age. Conclusions: In a community group practice, adherence to standard of care recommendations for higher stage MIBC patients to receive NAC are significantly higher than recently reported values, 50% vs 12%, respectfully. This was achieved while maintaining acceptable time to cystectomy. This supports our hypothesis that when barriers to care are decreased in a community group practice, high quality standards of care can be effectively delivered. In the future, 5 year overall survival will also be important to evaluate in this population.
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Habibullah, Muzafar Shah. "The Rationality Of Economic Forecasts: The Cases Of Rubber, Oil Palm, Forestry And Mining Sector." Agro Ekonomi 10, no. 1 (November 29, 2016): 67. http://dx.doi.org/10.22146/agroekonomi.16788.
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Forecasts of economic variables is very important for planning and policy making purposes. Forecasts is an important input in decision making processes because obtaining reliable forecasts of some relevant macroeconomic variables is necessary for efficient management of funds, time and resources.Business has always recognised the need for a view of the future and has used explicit forecasts in the design and execution of their economic andJor business policies. For example, a firm trying to decide upon its investment programme will have to take into account not only the current known set of circumstances but also the unknown economic and business conditions in the future. The firm has to form a view about the future, such as the likely sales, costs, prices, competitors' reactions, labour requirements, government regulations and so on. These views about the future values of economic variables are frequently referred to as 'expectations', that is, what the firm expects to happen in the future.In recent years the performances of many microeconomics and macroeconomics series have been erratic. For example, rate of inflation, price of crude oil, prices of primary commodities, rate of interest and other pertinent economic variables have been fluctuating widely and have caused concern among the public, politicians, economists and also the businessmen. According to Mayes (l 981), with such non-uniformity of economic variables observed in the last two decades, the role of expectations has become more relevant in the economic agents' decision making process. Mayes (1981) further states that under the present conditions it has become more important to consider what expectations actually are and how they are formed.The value of economic forecasts of certain macroeconomic variables can be derived from several methods. The three main methods for deriving economic forecasts are (i) time series, (ii) econometric models, and (iii) survey of intentions of concerned agents and organizations. Time seriesanalysis and econometric modeling are the two most widely used methods in economic forecasting, but Holden and Peel (1983) had noted their drawbacks. Recently, economists have turned their direction of interest in evaluating the rationality of economic forecasts from surveys of market participants. The empirical literature on the direct tests of the rational expectations hypothesis is vast and growing. Holden et al. (1985), Lovell (1986), Wallis (1989), Maddala (1991) and Pesaran (1991) had reviewed some of these studies. The aim was to determine whether survey data on economic forecasts are accurate in the Muth's (1961) sense, that is, whether participating economic agents used all available information at the time forecasts are made. in other words, the rational expectations hypothesis of the economic forecast was put to test. In general, the empirical studies do not support the rational expectations hypothesis.Most of the studies carried out to evaluate the rationality of business firms' forecasts of economic variables were conducted on developed nations. Madsen (1993) studies the formation of output expectations in manufacturing industry in Japan, Denmark, Finland, France, Germany, Netherlands, Norway, Sweden and the United Kingdom. He found that the rational expectations hypothesis was weakly rejected. Williams (1988) and Chazelas (1988) found investment forecasts biased predictors of the actual investment value for firms in the United Kingdom and France. Meganck et a!. (1988) have concluded that investment forecasts of the manufacturing firm in Belgium were unbiased predictors of the actual values. However. Daub (1982) failed to find any rationality of the Canadian capital investment intention survey data. On the other hand. a study by Leonard (1982) on employment forecasts by the United States services sectors found that the forecasts were biased and the rationality of these employment forecasts rejected.The purpose of this paper is to present some empirical evidence on the rationality of agricultural firm managers' expectations using survey data. This study is important because it adds to the current literature on the testing of rationality of survey data, in particular, it provides empirical evidence from the perspective of a developing country. As for the country under study, the finding of the study could establish whether the forecasts documented by such survey are accurate or not; and if not, ways to produce more accurate forecasts must be found. 'Rationality' in this paper means that managers in agricultural firms have unbiased expectations and efficiently utilised available information at the time the forecasts are made.
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Kibkalo, D. V., S. B. Borovkov, N. I. Korenev, V. N. Borovkova, and Kh A. Popova. "ВІДМІННОСТІ СКЛАДУ КРОВІ ПЕРИФЕРИЧНИХ І ЦЕНТРАЛЬНИХ ВЕН У СВИНЕЙ." Scientific Messenger of LNU of Veterinary Medicine and Biotechnology 18, no. 3(70) (September 9, 2016): 132–36. http://dx.doi.org/10.15421/nvlvet7031.
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Among laboratory researches in animals the most widespread is the common blood test that can determine hidden changes in organs and tissues, monitor the effectiveness of therapeutic and preventive measures to predict outcome of disease. The question of the legality comparing the results of blood analysis from central veins with rates that are developed from capillary and peripheral vessels blood is studied in the article. Researches were conducted in seven pigs of ukrainian white breed in age 2–4 months. Blood was collected in the morning before feeding by puncture of ear vein, orbital sinus and cranial vena cava. From each animal were picked out 3 blood samples. For taking blood were applied the vacuum blood collection systems. In blood were determined the number of erythrocytes, leukocytes and hemoglobin by conventional methods (Kibkalo et al., 2016). From the results of leukocyte profile the major differences were found in the number of eosinophils whose content was significantly higher (r≤ 0.001) in the blood of ear veins. Should be noted that this index was much higher than the norm, which is possible associated with the pathological process. But their level in blood of the cranial vena cava and eye sinus was normal. Therefore, this question needs further study. Also found significantly lower (r ≤ 0.01) level of lymphocytes in the blood from the ear vein. In the vena cava were not found monocytes and basophils unlike eye sinus and ear veins, in the last their detected more. Based on the foregoing, it can be noted that in the blood of peripheral veins are registered larger number of granulocytes, which in future will be tissue macrophages. Neutrophils, monocytes, basophils and eosinophils have the ability to attach to the capillaries and small vessels walls. So they are providing the cellular immunity. In blood of central vessels are more lymphocytes that provides humoral immunity in the bloodstream. Perspectives of the next studies will be comparing the hematological results that are realized on automatic hematology analyzer from ear vein, eye sinus and cranial vena cava from the same piglets.
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Brucks, Eric Brucks, Sumana Veeravelli, Ritika Halder, Francisco Javier Martinez, Jorge Andres Leiva, Kathylynn Saboda, Denise Roe, Hani M. Babiker, Ali McBride, and Alejandro Recio-Boiles. "Retrospective Real-World Analysis of the Primary Safety Outcomes in Venous Thromboembolism of High-Risk Major Bleeding Cancer Patients Receiving Therapeutic Anticoagulation." Blood 136, Supplement 1 (November 5, 2020): 15–16. http://dx.doi.org/10.1182/blood-2020-139641.
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Introduction The therapeutic anticoagulation of cancer-associated venous thromboembolism (VTE) is challenging because of the increased risk for thromboembolic recurrence and major bleeds (MB). Direct oral anticoagulants (DOACs) have emerged over Low Molecular Weight Heparin (LMWH) as a preferred treatment option by improving efficacy without compromising safety. Despite these advantages, major bleeding was noted to be a safety concern in recent randomized clinical trials, mainly for gastrointestinal (GI) and genitourinary (GU) high-risk cancer patients. We evaluated our cancer center's institutional experience to determine the safety signals among VTE treatments and clinical risk factors which can predict an adverse outcome to further develop our clinical practice decisions in oncology patients. Methods This is a retrospective chart review of patients receiving DOACs and LMWH with histologically proven GI or GU malignancy and symptomatic or incidental VTE treated at The University of Arizona Cancer Center from November 2013 to February 2020. Patients were excluded if DOACs were prescribed for any other reason not related to VTE, or the thrombotic event was determined to be unrelated to active malignancy. The primary safety outcome was defined as documented major bleeding by hemoglobin reduction of ≥2 g/dL, transfusion of ≥2 units of Packed Red Blood Cells, bleeding in a critical site, or bleeding contributing to death. The secondary efficacy outcome was defined as documented recurrent deep vein thrombosis (DVT), nonfatal pulmonary embolism (PE), or fatal PE. Data was collected as individually and composite outcome (MB+rVTE) before six months. Continuous non-normally distributed data are compared using the non-parametric Kruskal-Wallis Rank Sum. Categorical data are compared using χ2 or Fisher's exact test. Logistic regression was used to assess the relationship between anticoagulant therapy and the 3 outcome measurements. The relationship between therapies was adjusted for clinical risk factors using logistic regression. Statistical analyses were performed using Stata16. Results Our review included 160 patients with similar baseline characteristics who were prescribed enoxaparin (n=53), apixaban (n=55), and rivaroxaban (n=52) except for white race and active smokers [Table 1]. Primary MB outcome events at six months were 7.5%, 10.9%, and 17.3% for enoxaparin, apixaban, and rivaroxaban, with no statistical difference among therapies or cancer type [p>0.05]. Secondary rVTE outcome events at six months were 7.5%, 3.6%, and 5.7% for enoxaparin, apixaban, and rivaroxaban, respectively, with no significant difference among therapies or cancer type [p>0.05]. There were no differences in individual or composite outcomes of LMWH, apixaban, rivaroxaban, or DOAC by GI or GU cancer type. There are no statistically significant clinical associations between anticoagulation therapy by the three outcome measurements in either GI or GU cancer. Beyond six months on enoxaparin, apixaban, and rivaroxaban, there were 5.6%, 3.6%, and 5.7% added events to MB, and 3.7%, 1.8%, and 0% to rVTE, respectively. Conclusions Our retrospective review has shown similar efficacy in preventing recurrent VTE among anticoagulants and indirectly equivalent to those published by the randomized clinical trials. Notably, the rate of MB for our real-world high-risk GI/GU cancer was 2.8 times higher in patients receiving DOACs compared to those on clinical trial [MB 6% SELECT-D Young et al. 2018 and MB 3.8% Caravaggio Agnelli et al. 2020] and in agreement with a recent meta-analysis [relative risk GI 1.9 and GU 4.9, Giustozzi et al. 2020]. We recognized there are inherited selection bias in both clinical trials and retrospective studies, although baseline characteristics are similar. Future clinical trial designs should consider including real-world high-risk patients according to associated clinical risk factors to aid in the appropriate choice of therapeutic anticoagulation. Disclosures No relevant conflicts of interest to declare.
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Heitzer, Andrew M., Jennifer Longoria, Evadnie Rampersaud, Sara Rashkin, Jeremie H. Estepp, Victoria Okhomina, Winfred Wang, et al. "Fetal Hemoglobin Mediates the Effect of Beta Globin Gene Polymorphisms on Neurocognitive Functioning in Sickle Cell Disease." Blood 136, Supplement 1 (November 5, 2020): 23–24. http://dx.doi.org/10.1182/blood-2020-137065.
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Background: Fetal hemoglobin (HbF) is the most influential modifier of the clinical and hematologic phenotype of sickle cell disease (SCD) and is highly heritable. Low HbF is independently associated with increased white matter changes on brain imaging and poorer performance on neurocognitive measures (Ruffiuex, Child Neuropsychology, 2013). Our previous work has shown that 11 SNPs in three genes (BCL11A, MYB, and β-globin), contribute over 20% of the variance in HbF (Rampersaud, Kang. et al., 2020, under review). Clinically, these HbF-associated SNPs are associated with disease severity and frequency of pain events. However, the neurocognitive implications of these SNPs have yet to be explored. As part of a prospective longitudinal cohort study, the Sickle Cell Clinical Research and Intervention Program (SCCRIP), we evaluated the relationship between HbF-associated SNPs and neurocognitive functioning in SCD patients. Methods: We included 257 patients with SCD (69% HbSS/HbSβ0-thalassemia). The median age of participants was 13 years (range 4 - 25). We extracted genotypes for the 11 HbF-associated SNPs from whole genome sequencing data and analyzed them based on an additive genetic model. Following informed consent, patients completed a battery of gold-standard neurocognitive measures, supervised by a psychologist, assessing IQ, verbal and perceptual reasoning, working memory, processing speed, sustained attention, and executive functioning skills. HbF was the average value of measurements collected within 3 months of neurocognitive assessment, or the closest value. In univariate analyses, Kruskal-Wallis rank sum test was used to assess the associations of the 11 HbF-associated SNPs with neurocognitive measures. Linear regression was used to examine these associations adjusting for age, sickle genotype, hydroxyurea exposure, socioeconomic status (index of social vulnerability) and 5 principal components to adjust for population stratification. Benjamini and Hochberg false discovery rate (FDR) was used for multiple corrections and FDR adjusted p (pFDR)<0.05 was considered significant for all analyses. Mediation analyses (Imai, Psychological Methods, 2010) were used to evaluate the indirect effects of HbF-associated SNPs on neurocognitive outcomes via HbF. Results: One SNP in the β-globin gene, rs968857, was associated with performance on measures of IQ, verbal reasoning, working memory, and executive functioning by Kruskal-Wallis rank sum test (Figure 1) and by linear regression adjusting for covariates listed above at pFDR <0.05. HbF expression was positively associated with IQ and verbal reasoning scores at pFDR <0.05 using linear regression adjusting for age, sickle genotype, hydroxyurea exposure, and socioeconomic status. HbF mediated the relationship between rs968857 and scores on IQ and verbal reasoning measures at pFDR <0.05 (Figure 2). The direct effect of rs968857 on neurocognitive functioning remained significant following inclusion of HbF at pFDR <0.05, indicating partial mediation. Full linear regression models with rs968857, HbF, and covariates accounted for 10.8%, 14.5%, 6.4%, and 8.3% of the variance in IQ, verbal reasoning, working memory, and executive functioning measures, respectively. Conclusions: This is the first study to demonstrate a relationship between genetic modifiers of SCD and neurocognitive functioning. Beyond findings on neuroimaging and sociodemographic factors, there is little known about risk for neurocognitive deficits in SCD. The present results suggest an influence of SNP rs968857 on cognitive function, which was partially mediated by expression of HbF. rs968857, is one of four SNPs that defines almost all β-globin gene cluster haplotypes and influences HbF levels in SCD. How this SNP effects HbF and neurocognition is unknown and requires further investigation of its mechanism. The highly heritable nature of HbF may allow for future use of precision medicine. SCD patients could be stratified according to risk for neurocognitive deficits to utilize early intervention strategies, informed by genetic polymorphisms. Correlation with neuroimaging will help further elucidate the relationship between genetic modifiers and neurocognitive functioning. Future trials with larger samples are needed to validate our findings and investigate if the observed relationships differ by age or hydroxyurea treatment status. Disclosures Estepp: Daiichi Sankyo, Esperion, Global Blood Therapeutics: Consultancy; Global Blood Therapeutics, Forma Therapeutics, Pfizer, Eli Lilly and Co: Research Funding; ASH, NHLBI: Research Funding. King:Amphivena Therapeutics: Research Funding; Bioline: Consultancy; Celgene: Consultancy; Cell Works: Consultancy; Incyte: Consultancy; Magenta Therapeutics: Membership on an entity's Board of Directors or advisory committees; Novimmune: Research Funding; RiverVest: Consultancy; Tioma Therapuetics: Consultancy; WUGEN: Current equity holder in private company. Hankins:Novartis: Research Funding; National Heart, Lung, and Blood Institute: Honoraria, Research Funding; UptoDate: Consultancy; Global Blood Therapeutics: Consultancy, Research Funding; MJH Life Sciences: Consultancy, Patents & Royalties; American Society of Pediatric Hematology/Oncology: Honoraria; LINKS Incorporate Foundation: Research Funding.
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Macqueen, R. W. "Symposium: Role of organisms and organic matter in ore deposition/Le rôle des organismes et de la matière organique dans la formation des gisements métallifères." Canadian Journal of Earth Sciences 22, no. 12 (December 1, 1985): 1890–92. http://dx.doi.org/10.1139/e85-203.
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The following seven papers were presented on May 16, 1984, at the Geological Association of Canada and Mineralogical Association of Canada joint annual meeting. The special session, organized by R. W. Macqueen and J. A. Coope, contained 10 papers and was sponsored by the Mineral Deposits Division of the Geological Association of Canada.Our objective in organizing the special session was to examine organically based processes and relationships that may be of major importance to the origin of ore deposits. As noted by Fyfe (1984), the concept of the geochemical cycle focuses attention on pathways of chemical elements and isotopes of the Earth's system during geologic history. It is clear from the chemistry of carbon-rich materials that a wide range of elements is concentrated directly or indirectly by biological processes operating as part of the geochemical cycle. Two of the papers of the special session examine some of these concentration processes, although definitive links to actual ore deposits cannot be made yet. Beveridge and Fyfe document the remarkable ability of the anionic cell walls of certain bacteria to concentrate metals and to provide sites for nucleation and growth of minerals. In a related paper, Mann and Fyfe show that several species of simple freshwater green algae readily concentrate large amounts of uranium under both experimental and natural conditions (Elliot Lake and Thames River, Ontario).Two papers deal with aspects of sulphate reduction. Birnbaum and Wireman describe controlled experiments that suggest that sulphate-reducing bacteria may be involved in the selective replacement of sulphate-evaporite minerals by silica and in the precipitation of silica in association with sulphide mineral phases in banded iron formations. Their work focuses directly on the effect that bacterial sulphate reduction has on silica solubility. Trudinger et al. examine the question of mechanisms of sulphate reduction at temperatures less than 200 °C and the bearing this has on origin of sulphide for low-temperature sulphide ore deposits. Although there is empirical evidence favouring abiological sulphate reduction at temperatures in the vicinity of 100 °C, Trudinger et al. have not been able to demonstrate abiological reduction of sulphate under controlled laboratory conditions and at temperatures under about 200 °C. Perhaps catalysts, as yet undiscovered, are involved in this process in nature.Impressive progress has been made in understanding the diagenetic evolution of organic matter in response to heat and pressure in geological environments: excellent reviews are found in Barnes et al. (1984) and Bustin et al. (1985). Simoneit's paper examines and reviews the genesis of petroleum in a most unusual setting, that of the active ocean ridge spreading centre of Guaymas Basin, Gulf of California. There, in the vicinity of black smokers and associated metallic sulphide deposits, petroleum originates instantaneously geologically as a result of hydrothermal activity. The question of genetic involvement of organic matter in the origin of the metallic sulphides (e.g., reduction of sulphate to H2S) cannot be answered yet for this setting with the available data.The final two special session papers included here are concerned with organic matter associated with mineralization in Canadian Shield Precambrian settings. Willingham et al. demonstrate that Elliot Lake – Blind River Early Proterozoic uranium deposits with minor amounts of associated gold also contain kerogen-like organic matter. Some of this organic matter has anomalously rich amounts of gold and uranium and appears to have originated as mats of cyanobacteria, possibly with the ability to concentrate these metals. For a number of settings in the Archean-aged Abitibi greenstone belt of Ontario and Quebec, Springer demonstrates that carbon, at least partly of organic origin, is closely associated with some gold deposits. Her interpretation is that carbon activated by shear-zone-associated hydrothermal fluids has provided sites for fixing some of the gold.Three of the papers given at the special session are not included here. H. T. Shacklette reviewed metal uptake by young conifer trees, demonstrating that nursery-grown seedlings of several species readily concentrated a variety of metals, including lead, zinc, tin, and gold, over a 7 year period. This work is of interest to those involved in geochemical prospecting and is now published elsewhere (King et al. 1984). R. W. Macqueen presented quantitative data on the genesis of sulphide by abiological bitumen–sulphate reactions at the Pine Point lead–zinc property, Northwest Territories, Canada (Macqueen and Powell 1983; Powell and Macqueen 1984). Although Trudinger et al. have not been able to demonstrate abiological reduction of sulphate at temperatures approximating those of Pine Point [Formula: see text], the data presented by Macqueen (Powell and Macqueen 1984) are consistent with the amounts, alteration, and composition of bitumens at Pine Point, as well as with the presence of native sulphur and the sulphur isotope compositions of the various Pine Point sulphur species. This work is continuing, and a more extensive account is in preparation. J. R. Watterson examined relationships between freezing climates and the local chemical behaviour of gold in the weathering cycle, concluding that ice-induced accumulation of organic acids, bacteria, and other organic matter at mineral surfaces may increase rates of chemical attack, leading to dissolution of normally insoluble metals such as gold (Watterson 1986).Interest in organic aspects of the geochemical cycle, including ore deposition, is growing dramatically (e.g., Fyfe 1984). Although the following papers address a limited range of topics within the field, they do indicate some of the diversity and variety of active processes and associations between metallic elements and organic components. Perhaps, in the not too distant future, we will be able to identify or even discover whole classes of ore deposits that owe their origin directly to organic influences operating within the geochemical cycle.
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Diorio, Caroline, Kevin O. McNerney, Michele P. Lambert, Michele Paessler, Julie Chase, Kandace Gollomp, Benjamin L. Laskin, et al. "Evidence of Microangiopathy in Children with Sars-Cov-2 Regardless of Clinical Presentation." Blood 136, Supplement 1 (November 5, 2020): 28–29. http://dx.doi.org/10.1182/blood-2020-137240.
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Introduction: During the Coronavirus Disease 2019 (COVID-19) pandemic caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), 3 distinct phenotypes have emerged in children. The majority of children have mild or no symptoms. Similar to adults, a minority of children can be severely affected with respiratory distress requiring intensive care. Finally, they may develop a phenomenon presumed unique to children termed Multisystem Inflammatory Syndrome in Children (MIS-C). MIS-C is a hyperinflammatory syndrome characterized by fever and organ dysfunction (particularly cardiac) in the setting of recent COVID-19 infection. Reports from the adult literature have invoked thrombotic microangiopathy (TMA) and complement activation as a potential cause for severe manifestations of COVID-19 (Zhang et al. NEJM. 2020; Campbell et al. Circulation 2020). Soluble C5b9 (sC5b-9), the terminal complement complex, has been implicated as a marker of hematopoietic stem cell transplant associated TMA (HSCT-TMA; Jodele et al. Blood 2014). We sought to elucidate the role of terminal complement activation and TMA in the different pediatric disease phenotypes. Methods: We enrolled children admitted to the Children's Hospital of Philadelphia during the COVID-19 pandemic who had evidence of SARS-CoV-2 infection on reverse transcriptase polymerase chain reaction (RT-PCR) from mucosa, or met clinical criteria for MIS-C. Patients (pts) were classified in to 3 categories: minimal COVID-19 symptoms or incidental finding of SARS-CoV-2 infection, severe COVID-19 requiring ventilatory support, or MIS-C. To investigate the role of TMA in children with COVID-19 we measured sC5b-9 in plasma of pts with the 3 manifestations of SARS-CoV-2, and in healthy controls. sC5b9 was measured in triplicate at two dilutions by ELISA. Proinflammatory cytokines were measured using V-Plex Pro-inflammatory Panel 1 Human Kits and analyzed on a QuickPlex SQ120. P-values were computed using Dunn's multiple comparisons test after Kruskal-Wallis testing. Blood smears were examined by a hematologist and hematopathologist for schistocytes. Results: 50 pts were enrolled on whom complete sC5b9 data were available: minimal COVID-19 (N=18), severe COVID-19 (N=11), and MIS-C (N=21). Plasma was obtained on healthy controls (N=26). The median sC5b9 level in healthy controls (57 ng/mL) differed significantly (p<0.001 in each case; Figure 1A) from that in pts with minimal disease (392 ng/mL), severe disease (646 ng/mL), and MIS-C (630 ng/mL); differences between MIS-C, minimal, and severe were not statistically significant. Elevations in sC5b9 correlated in a statistically significant manner with the maximum creatinine and blood urea nitrogen (BUN) measured during hospitalization (Figure 1B&C), but not age (p=0.512). sC5b9 did not correlate with lactate dehydrogenase (LDH), nor with the lowest levels of fibrinogen, hemoglobin or platelet counts. Of pts with available data, 19/26 (73.1%) had elevated LDH, 2/31 (6.4%) had hypofibrinogenemia, 35/47 (74.5%) were anemic, and 28/47 (59.6%) were thrombocytopenic. Pro-inflammatory cytokines were measured. Of particular interest to TMA is the neutrophil chemotactic factor IL-8, because of its role as a marker of endothelial damage (Dvorak et al. Front Pediatr 2019). Levels of IL-8 differed significantly between pts with MIS-C (p=0.0166) or pts with severe COVID-19 (p=0.0079), when compared to minimal COVID-19 pts; but not between pts with MIS-C and severe disease (p = 0.99). Blood smears were available on 34 patients. Schistocytes were present in 13/15 (87%) patients with MIS-C, 7/8 (87%) patients with severe COVID-19 and 5/11 (45%) patients with minimal COVID-19 (χ2=6.59, p=0.037). Conclusions: We demonstrate derangements of the final common pathway of complement activation in children with the 3 presentations of SARS-CoV-2. Strikingly, sC5b9s were abnormal even in children with minimal disease or incidental infection. Renal dysfunction correlated with elevations in sC5b9, strengthening the evidence that TMA plays a role in the pathophysiology of SARS-CoV-2 infection. Future work is aimed at further characterizing the role of the complement cascade in the pathogenesis of MIS-C and COVID-19 in children. The long-term complications of endothelial damage and complement activation are unknown and extended follow-up is warranted. Figure 1 Disclosures Diorio: Children's Hospital of Philadelphia: Research Funding; University of Pennsylvania: Research Funding. Lambert:22qSociety: Consultancy; RDMD ITP study: Consultancy; Octapharma: Consultancy, Research Funding; Educational Concepts in Medicine: Consultancy; Shionogi: Consultancy; Novartis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Argenix: Consultancy; CdLS Foundation: Consultancy; Sysmex: Research Funding; Dova: Consultancy, Membership on an entity's Board of Directors or advisory committees; Principia: Consultancy, Membership on an entity's Board of Directors or advisory committees; ClinGen: Honoraria; Platelet Disorder Support Association (PDSA): Consultancy; AstraZeneca: Research Funding; Bayer: Consultancy; ITP Australia: Consultancy. Henrickson:Horizon Pharma: Other: ad hoc board meeting. Odom John:Burroughs Wellcome: Research Funding; NIAID: Research Funding. Bassiri:CSL Behring: Other: Spouse receives stocks . Behrens:NIH/NIAID: Research Funding. Teachey:Janssen: Consultancy; Amgen: Consultancy; La Roche: Consultancy; Sobi: Consultancy.
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Vita, Bruna De, Loreta L. Campos, Amanda J. Listoni, Ian Martin, Regina K. Takahira, Bruna R. Curcio, Fernanda C. Landim-Alvarenga, and Nereu C. Prestes. "Comparação da composição bioquímica do líquido amniótico equino colhido em diferentes estágios gestacionais e no momento do parto." Pesquisa Veterinária Brasileira 34, no. 6 (June 2014): 582–88. http://dx.doi.org/10.1590/s0100-736x2014000600013.
Full textAbstract:
A viabilidade e maturidade fetais podem ser estimadas através da avaliação dos fluídos fetais em muitas espécies, no entanto a composição bioquímica do líquido amniótico durante a gestação ainda não está bem definida para a espécie equina. O objetivo deste estudo foi estabelecer e comparar o perfil bioquímico do liquido amniótico em diferentes momentos da gestação e no momento do parto para um melhor entendimento da fisiologia da gestação de equinos. Foram avaliados valores encontrados para pH, osmolaridade, glicose, uréia, creatinina, gamma-GT, sódio, potássio, cloretos e proteína total no liquido amniótico colhido de 122 éguas comparando-se os resultados encontrados entre as colheitas em terço inicial (TI), médio (TM) e final (TF) da gestação e no momento do parto (MP). As amostras colhidas nos períodos gestacionais foram realizadas em frigoríficos abatedouros. As idades gestacionais (IG), em dias, foram definidas através de fórmula de regressão sugerida por Naves et al. (2008), utilizando-se a mensuração crânio-caudal dos fetos. Devido a presença de graus variados de assimetria e desvios de um padrão Gaussiano de distribuição, o teste de Kruskal-Wallis foi usado para comparar a mediana de cada variável-resposta entre os grupos de estudo. Quando houve evidência significante de que pelo menos uma das medianas era diferente das outras, o teste de Wilcoxon foi usado para realizar comparações múltiplas entre os grupos. O método de Bonferroni foi usado para ajustar o valor-P resultante das comparações múltiplas. A análise estatística foi realizada com o procedimento PROC NPAR1WAY e significância estatística foi definida como p<0,05 .pH e osmolaridade do líquido amniótico equino não sofreram alterações significantes entre os terços gestacionais e no momento do parto. Os valores encontrados para glicose foram significativamente menores nas amostras do grupo TF e MP. As concentrações de uréia tenderam ser estatisticamente diferente em pelo menos um dos grupos estudados e foi observado um padrão crescente nas concentrações de creatinina durante as fases gestacionais, enquanto que a concentração encontrada no grupo MP foi igual a concentração encontrada no grupo TF. Valores para gamma GT diferiram apenas entre os grupos TF e MP e mais estudos devem ser conduzidos sobre sua função no liquido amniótico das espécies domésticas. Os valores de sódio e cloretos não diferiram significativamente entre os grupos estudados e as concentrações de potássio diferiram apenas entre os grupos TF e MP refletindo a manutenção do equilíbrio eletrolítico do líquido amniótico equino durante a gestação. As concentrações de proteínas totais variaram de maneira heterogênea entre os grupos, porém todos estes demonstraram baixas concentrações. Concluímos que a composição bioquímica do liquido amniótico equino varia de acordo com o desenvolvimento fetal e pode ser utilizada como mensuração da viabilidade e maturidade do feto no futuro, no entanto devido ao pequeno número de estudos conduzidos e diferenças encontradas em seus resultados, outros estudos devem ser realizados para a melhor definição do perfil bioquímico do líquido amniótico equino durante as fases gestacionais e no momento do parto.