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1

Warrant and proper function. Oxford University Press, 1993.

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2

Warrant and Proper Function [e-book]. Oxford University Press, 1993.

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3

Graham, Peter J., and Nikolaj J. L. L. Pedersen, eds. Epistemic Entitlement. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198713524.001.0001.

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This volume collects new work on epistemic entitlement partly motivated by Tyler Burge’s and Crispin Wright’s seemingly identical distinctions between two forms of warrant: entitlement and justification. But despite nomenclature, Burge and Wright are engaged in different projects. Recognizing that we cannot provide a non-question begging evidential reply to the sceptic, Wright seeks an a priori, non-evidential, rational right to accept and claim to know cornerstone propositions. He calls these rights epistemic entitlements. Epistemic justifications are evidential warrants, contributors to know
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4

Vairappan, Charles S. Ecological Chemicals as Ecosystem Function Mediaters and Potential Lead Pharmaceuticals. UMS Press, 2021. http://dx.doi.org/10.51200/ecologicalchemicalsumspress2021-978-967-2962-94-6.

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Relationship between functioning ecosystem services and human wellbeing has been established as a bridge connecting nature and society. It has also become central pillar of sustainability science and dictates the paradigms of sustainable development. But, conceptual frameworks that systematically integrates the important roles played by natural ecological chemicals by establishing empirical links between the nature and ecology not only varies, but lacks clear support. The value of ecological chemicals as ecosystem derived natural products warrants explicit acknowledgement, only then trade-offs
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5

Boules, Adel N. Fundamentals of Mathematical Analysis. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198868781.001.0001.

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Fundamentals of Mathematical Analysis is a beginning graduate textbook on real and functional analysis, with a substantial component on topology. The three leading chapters furnish background information on the real and complex number fields, a concise introduction to set theory, and a rigorous treatment of vector spaces. Instructors can choose material from this part as their students’ background warrants. Chapter 4 is the spine of the book and is essential for an effective reading of the rest of the book. It is an extensive study of metric spaces, including the core topics of completeness, c
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6

O’Brien, Alastair. Management of acute or chronic hepatic failure in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0200.

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Acute on chronic liver failure is characterized by an acute deterioration of liver function in a patient with previously compensated cirrhosis secondary to a precipitating event. It is most commonly associated with a very poor prognosis and early identification of the precipitating cause is essential to successfully attempt to reverse decompensation. The most common precipitant is infection and a high index of suspicion is required. Other management is largely supportive with close attention to renal dysfunction being particularly important. All patients admitted to the intensive care unit wit
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7

Breitbart, William, and Anna L. Dickerman. Fatigue and HIV. Edited by Mary Ann Cohen, Jack M. Gorman, Jeffrey M. Jacobson, Paul Volberding, and Scott Letendre. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199392742.003.0024.

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Fatigue is commonly reported by persons with HIV and AIDS and is associated with impaired physical function, reduced quality of life, and suboptimal treatment adherence. Patients regard fatigue as an important condition to be addressed because it is disabling and distressing. In the past, fatigue was overlooked and undertreated by physicians, but clinicians caring for persons with HIV and AIDS have been giving more attention to symptom management and patients’ quality of life. Increased attention to symptom management in HIV and AIDS warrants familiarity with major issues in evaluation and tre
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Eder, Lihi. The clinical course and outcome of psoriatic arthritis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198737582.003.0021.

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In contrast to early reports, it is now appreciated that psoriatic arthritis (PsA) can present as a destructive, progressive, and disabling arthritis with consequences as severe as those of rheumatoid arthritis. Longitudinal cohort studies of PsA patients contributed important knowledge about long-term outcomes, such as development of structural joint damage, remission achievement, and physical function. These studies identified predictors for improved outcomes including male gender and lower burden of inflammation at presentation while delayed diagnosis, disability, and joint damage are assoc
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Coppock, Dagan, and William R. Short. Immune Reconstitution Inflammatory Syndrome. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0048.

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Immune reconstitution inflammatory syndrome (IRIS) is associated with either worsening of a recognized infection (paradoxical IRIS) or an unrecognized infection (unmasking IRIS), which occurs in the setting of improved immunologic function. Most patients presenting with IRIS should be maintained on antiretroviral therapy (ART) along with treatment for the associated infection. Screening for latent tuberculosis infection should be undertaken in all HIV-infected patients. In paradoxical IRIS, it is crucial to exclude alternate diagnoses and ensure the patient is receiving appropriate treatment f
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10

Gerken, Mikkel. Thought and Talk about Knowledge. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198803454.003.0002.

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Chapter 1 outlines the core assumptions of the epistemological framework to be defended. For example, a variety of a relevant-alternatives framework that appeals to normal circumstances is adopted, as is a competence epistemology according to which S may obtain knowledge and warranted belief only by exercising a cognitive competence. Moving from the epistemological framework to our folk epistemology, the ways in which the term ‘knowledge’ is central to our folk epistemology are considered. Special emphasis is given to knowledge ascriptions’ social and communicative functions. Thus, Chapter 1 i
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11

Pivovarova, Ekaterina, and Philip J. Candilis. Safety Monitoring and Withdrawal of Psychiatric Research Participants. Edited by John Z. Sadler, K. W. M. Fulford, and Werdie (C W. ). van Staden. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780198732372.013.14.

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This chapter examines how clinical investigators ensure the safety of psychiatric research participants while maintaining the integrity of research protocols. It discusses the ethical issues arising from data monitoring, disclosure of interim data, and termination of clinical trials. It outlines unique features of psychiatric research and related cultural issues that may warrant consideration before and during clinical trials. It focuses on the Data Safety Monitoring Boards (DSMBs) overseeing clinical trials their development of detailed plans for monitoring safety and protocol adherence. It l
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12

Noonan, Máire. Dutch and German R-pronouns and P-stranding. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198778264.003.0010.

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This chapter explores the fine structure of R-pronouns, spatial PPs, and P-stranding constructions. The guiding hypothesis and theoretical backdrop is that an extended clausal structure is generalized to all categories, including adpositions, (P). The empirical evidence comes from a comparison of the morphosyntactic distribution of the ‘r’ in German and Dutch so-called R-pronouns (locative pronouns) and P-stranding constructions, and from complex spatial PPs in Colloquial German. The chapter argues that a comparative approach to these closely related Germanic languages warrants the decompositi
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13

Healey, Richard. Overview: A New Kind of Science. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198714057.003.0001.

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This overview introduces the book’s aim of showing how quantum theory marks a radical break from previous scientific theorizing: We are warranted in accepting the fundamental status within contemporary physics of a theory that posits no new physical entities or magnitudes of its own. By contrast with existing interpretations that attempt to say how the world could possibly be the way quantum theory says it is, a pragmatist takes understanding quantum theory to be a matter of knowing how it is applied, and how the theory’s various elements function in these applications. So Part I of the book o
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Cutter, Mary Ann G. How Is Breast Cancer Evaluated? Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190637033.003.0004.

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The question “How is breast cancer evaluated?” raises a host of considerations, including ones about the role of values in clinical concepts, the kinds of clinical values in medical thinking, and the extent to which our evaluations of clinical phenomenon provide clinical certainty. What we find is that, initially, breast cancer is a treatment warrant and appears to fit the view of a clinical entity that is value-neutral. But things are not as simple as one would initially think. Upon reflection, descriptions and explanations of breast cancer are nested in evaluative frames of reference through
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Sullivan, Mark, John Henderson, Inderbir Gill, and Nilay Patel. Upper urinary tract obstruction. Edited by John Reynard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0031.

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Obstructive uropathy refers to the clinical sequelae of impairment of free urinary flow in the urological tract. The clinical manifestation of obstructive uropathy depends on the level and duration of obstruction, whether it is partial or complete, and whether infection has supervened. Obstruction may be clinically silent—and incidental radiological, biochemical, or examination findings may suggest the diagnosis. The radiological techniques used to demonstrate obstruction can be divided into anatomical and functional studies. These include ultrasound, urography, cross-sectional imaging, mictur
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16

Graham, Peter J. Sincerity and the Reliability of Testimony. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198743965.003.0005.

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“Content Preservation” by Tyler Burge is one of the most influential articles in the epistemology of testimony. Burge argues for three theses: (1) That we enjoy a prima facie entitlement to take testimony (presentations-as-true) at face value, (2) That this entitlement has an a priori basis, based in the nature of reason, and (3) That in some cases testimony-based beliefs are warranted a priori. Most of the debate in the testimony literature is over the truth of (1). Most of the criticism of Burge’s paper focuses on (3). Burge has since abandoned (3). What about (2)? Burge’s argument for (2) i
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17

Barry, Amelia, and Guy Trudel. Bone and Joint Disease Following Critical Illness. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0025.

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Bone and joint processes take second stage to life-threatening organ failure in the setting of critical illness. However, bone and joint disorders can cause significant impairment in survivors of critical illness. Return to pre-admission function is often limited by acquired complications such as joint contractures, heterotopic ossification, and altered bone metabolism. Critical care physicians should maintain a high index of suspicion for joint contractures, as they are often asymptomatic but the source of enduring disability once the critical illness had receded. Research is needed to docume
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18

Yende, Sachin, and Derek C. Angus. Genetic Determinants of Sepsis Outcomes. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0027.

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Bone and joint processes take second stage to life-threatening organ failure in the setting of critical illness. However, bone and joint disorders can cause significant impairment in survivors of critical illness. Return to pre-admission function is often limited by acquired complications such as joint contractures, heterotopic ossification, and altered bone metabolism. Critical care physicians should maintain a high index of suspicion for joint contractures, as they are often asymptomatic but the source of enduring disability once the critical illness had receded. Research is needed to docume
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19

Neligan, Patrick J., and Clifford S. Deutschman. Management of metabolic acidosis in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0256.

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Metabolic acidosis (MA) commonly complicates critical illness, usually manifesting as a fall in arterial pH (<7.4) accompanied by a concomitant fall in serum bicarbonate concentration. Acidosis caused by unmeasured anions (UMA), can be distinguished from Hyperchloraemic acidosis by demonstrating a widening of the anion gap (AG). AG should be corrected for albumin and lactate. The base deficit (BD) calculates degree of metabolic acidosis and represents the amount of strong cation required to restore the pH to 7.4. Neither the AG nor the BD specify the cause of acidosis, and are unhelpful in
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AlJaroudi, Wael. Risk Assessment Before Noncardiac Surgery. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0014.

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Perioperative risk assessment is essential in screening patients before noncardiac surgery. Cardiovascular complications such as fatal and non-fatal myocardial infarction (MI), ventricular arrhythmia, pulmonary edema, and stroke are important in-hospital causes of morbidity and mortality intra and post-operatively. The optimal approach is to identify patients at increased risk so that appropriate testing and therapeutic interventions are undertaken a priori to minimize such risk. The initial preoperative evaluation includes identification of surgery-specific risk, patient exercise functional c
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