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Journal articles on the topic 'Warthin Starry Stain'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Mohammed Abdalla MA, Osman Amir, and Elnazir Mohammed E. "Detection of Helicobacter pylori (H. pylori) by histochemical stains in gastric biopsy comparing to immunohistochemistry." World Journal of Advanced Research and Reviews 15, no. 2 (2022): 155–59. http://dx.doi.org/10.30574/wjarr.2022.15.2.0793.

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Aim: A reliable diagnosis of Helicobacter pylori (H. pylori) is important in clinical practice and research. The aim of this study was to compare the sensitivity and specificity of Giemsa stain with hematoxylin and eosin (H&E), Toluidine blue, Gimenez and Warthin-Starry stain in detection of Helicobacter pylori (H. pylori) in gastric biopsy and also with immunohistochemistry (IHC) stain in detection of H. pylori organism in gastric biopsy. Method: A retrospective cross-sectional included 200 formalin-fixed paraffin-embedded (FFPE) gastric biopsies of age between 25 to 80 years in histopath

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Mohammed, Abdalla MA, Amir Osman, and Mohammed E. Elnazir. "Detection of Helicobacter pylori (H. pylori) by histochemical stains in gastric biopsy comparing to immunohistochemistry." World Journal of Advanced Research and Reviews 15, no. 2 (2022): 155–59. https://doi.org/10.5281/zenodo.7756057.

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<strong>Aim</strong>: A reliable diagnosis of <em>Helicobacter pylori </em>(<em>H. pylori</em>) is important in clinical practice and research. The aim of this study was to compare the sensitivity and specificity of Giemsa stain with hematoxylin and eosin (H&E), Toluidine blue, Gimenez and Warthin-Starry stain in detection of <em>Helicobacter pylori </em>(<em>H. pylori</em>) in gastric biopsy and also with immunohistochemistry (IHC) stain in detection of <em>H. pylori</em> organism in gastric biopsy. <strong>Method</strong>: A retrospective cross-sectional inc

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Sandhika, Willy. "DETECTION OF HELICOBACTER PYLORI INFECTION IN CHRONIC GASTRITIS BIOPSY SPECIMEN USING WARTHIN-STARRY AND MODIFIED GIEMSA STAIN IN DR SOETOMO HOSPITAL SURABAYA." Indonesian Journal of Tropical and Infectious Disease 7, no. 6 (2019): 150. http://dx.doi.org/10.20473/ijtid.v7i6.8404.

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Helicobacter pylori is a bacteria that commonly cause chronic gastritis. Identification of its infection is essential for eradication treatment. Detection of H.pylori bacteria in gastric biopsy specimen by histology method is a diagnostic tool that widely accepted because it is superior to serology examination. Although the bacteria can be seen in routinely Hematoxylin-Eosin staining, Modified Giemsa and Whartin Starry stain was commonly used to see the bacteria more clearly. Whartin Starry stain gives more contrast to the bacteria but modified Giemsa stain is preferable at many centres becaus

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Czubek, Anne. "Warthin-Starry Stain for Spirochetes in Tissue." Microscopy Today 5, no. 9 (1997): 18–19. http://dx.doi.org/10.1017/s1551929500060570.

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I had recently been involved in a computer group discussion about the Warth in-Starry stain. No one seems to like to do it, except me. Here is a procedure that my histology laboratory (The Toledo Hospital, Toledo, Ohio) received from Lee Luna, who was a consultant to our laboratory, just before his death, Any "tips-of-the-trade" I have added.

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BRANISLAV, KURELJUŠIĆ, SAVIĆ BOŽIDAR, JEZDIMIROVIĆ NEMANJA, et al. "PATOMORPHOLOGICAL DIAGNOSIS OF HEMORRHAGIC PROLIFERATIVE ENTEROPATHY IN SWINE." Contemporary Agriculture (2012) 61, no. 1-2 (2012): 68–74. https://doi.org/10.5281/zenodo.7260912.

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In this paper seven samples of the intestines originated from the naturally infected pigs, macroscopic, histochemically and immunohistochemically were examined. The caudal part of jejunum and ileum were affected. The affected intestine was thickened and dilated. The lumen of the ileum and colon contained one or more blood clots without feed contents. The rectum contained black tarry feces of mixed blood and digesta. The mucosal surface of the affected portion of intestine was markedly thickened without macroscopic erosions. Histological examination revealed: extensive degeneration, congestion,

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Jaramillo Delgado, Ingrid L., Diego A. Aranzazu Taborda, and Santiago Duque-Arias. "Descripción de alteraciones histopatológicas en riñones de <i>Rattus norvegicus</i> seropositivos a <i>Leptospira </i>spp." Revista de Investigaciones Veterinarias del Perú 35, no. 4 (2024): e25319. http://dx.doi.org/10.15381/rivep.v35i4.25319.

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The aim of this study was to describe the most common histopathological findings observed by Hematoxylin-Eosin staining in kidneys of Rattus norvegicus naturally infected and seropositive to Leptospira spp using the Microscopic Agglutination Test (MAT) technique. In total, 165 rodents were captured from three locations in Antioquia (Turbo and Medellín). Kidney samples were taken from the seropositive rodents by MAT and Hematoxylin-Eosin staining was used to evaluate the microscopic lesions and Warthin- Starry to visualize the bacteria. The most frequent morphological diagnoses were chronic int

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Paradis, Alain, Marie Gourdeau, Suzanne Lambert, et al. "Campylobacter pyloriDetection in Gastric Mucosa: Association with Gastritis." Canadian Journal of Gastroenterology 2, no. 3 (1988): 94–98. http://dx.doi.org/10.1155/1988/654129.

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ln order to evaluate the association between Camphlobacterpyloriand gastritis, two biopsies were taken from the duodenal bulb, antrum, body and fundus (and from lesions if there were any) in 100 consecutive patients referred to this gastroscopic clinic For each site, one biopsy was for histology and C pylon detection by Warthin-Starry staining, and the second biopsy was for culture. In addition, for each patient a gastric brushing was Gram stained. Twenty-one patients were excluded from the study. Among the remaining, 13 patients had positive biopsy culture for Cpyloriand, of these, 30 (91%) h

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8

Ohtani, Y., T. Yoshirio, and T. Akagi. "Ultrastructure of Warthin-Starry Stain-Positive Bacteria in Abscess-Forming Reticular Lymphadenitis." Pathology - Research and Practice 188, no. 3 (1992): 314–17. http://dx.doi.org/10.1016/s0344-0338(11)81210-0.

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9

Manzoor, Mohammad, Afreenish Amin, Saman Hussain, et al. "Correlation Between Histopathological Findings, CD4 Counts, and Treponeme Quantity in Microscopic Sections and Secondary Syphilis in HIV Positive Individuals." Pakistan BioMedical Journal 5, no. 1 (2022): 253–56. http://dx.doi.org/10.54393/pbmj.v5i1.320.

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Syphilis is not common, although HIV-infected people are far more likely to be infected than the general population. This may be caused by weakened cellular immunity due to HIV infection. This study aimed to find out the correlation between CD4 concentration and T. Pallidum occurrence. Methods: A assessment of a single institution identified ten patients with secondary syphilis diagnosed through a skin biopsy, positive syphilis serology, and high CD4 levels. There were 14 samples obtained from 13 individuals. Immunohistochemistry (IHC) was used to detect the presence of treponemes and CD4 leve

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Lai, Chester, and Eugene Healy. "The Warthin-Starry stain for detection of cutaneous melanin: more than a historical curiosity." Experimental Dermatology 25, no. 10 (2016): 763–64. http://dx.doi.org/10.1111/exd.13101.

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11

Rodríguez-Tovar, Luis E., Alejandra Villarreal-Marroquín, Alicia M. Nevárez-Garza, et al. "Histochemical study of Encephalitozoon cuniculi spores in the kidneys of naturally infected New Zealand rabbits." Journal of Veterinary Diagnostic Investigation 29, no. 3 (2017): 269–77. http://dx.doi.org/10.1177/1040638716668559.

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Encephalitozoon cuniculi is an important microsporidian pathogen that is considered an emergent, zoonotic, and opportunistic. It infects both domestic and laboratory rabbits, generating severe chronic interstitial and granulomatous nephritis with fibrosis and granulomatous encephalitis. Encephalitozoonosis is diagnosed in paraffin-embedded sections by examining the spores in the host tissues. The spores are difficult to observe when the samples are stained with hematoxylin and eosin (H&E), particularly when there is an inflammatory reaction and tissue damage. The spores are easily mistaken

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Fox, J. G., B. M. Edrise, E. B. Cabot, C. Beaucage, J. C. Murphy, and K. S. Prostak. "Campylobacter-like organisms isolated from gastric mucosa of ferrets." American Journal of Veterinary Research 47, no. 2 (1986): 236–39. https://doi.org/10.2460/ajvr.1986.47.02.236.

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SUMMARY Campylobacter-like organisms (clo) were isolated from gastric lesions in 1 ferret and gastric mucosa of 2 healthy ferrets. The organism was not isolated from biopsies of gastric mucosa of 14 other healthy ferrets, 1 of which had small gastric lesions located at the pylorus. Lesions from which clo were isolated were located in the antrum of 1 ferret and were classified as inflammation with repair. Affected gastric tissue was highly vascularized with fibrous connective tissue surrounding irregularly shaped glands. Necrosis and ulceration of adjacent mucosa also were observed. Using Warth

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Oyedeji, O. S., S. Rodgers, S. Q. Zia, and A. Ormsby. "Agreement and Intraobserver Variability in Detection of Helicobacter pylori Infection Using Routine Histology, H. pylori Immunohistochemical Stain, and Warthin-Starry Special Stain on Gastric Tissue Biopsy Samples." American Journal of Clinical Pathology 156, Supplement_1 (2021): S61. http://dx.doi.org/10.1093/ajcp/aqab191.126.

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Abstract Introduction/Objective Helicobacter pylori (HP) is a prevalent cause of gastritis in the US and worldwide. Accurate detection of the organism is important for appropriate treatment. Diagnosis is made using immunohistochemistry and special stains including Warthin-Starry stain (WS) which is low cost, technically easy to perform on tissue sections, and can be automated. We aimed to assess interobserver variability, reproducibility and validity of hematoxylin and eosin stain (H&E), WS and anti-Helicobacter pylori immunohistochemical staining (HP-IHC) for the histopathological identif

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Peng, Jinwu, Zhuoyang Fan, Hongmei Zheng, Junmi Lu, and Yuting Zhan. "Combined Application of Immunohistochemistry and Warthin-Starry Silver Stain on the Pathologic Diagnosis of Cat Scratch Disease." Applied Immunohistochemistry & Molecular Morphology 28, no. 10 (2020): 781–85. http://dx.doi.org/10.1097/pai.0000000000000829.

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Szeredi, L., A. Pospischil, L. Dencső, A. Mathis, and M. Dobos-Kovács. "A case of equine abortion caused by Encephalitozoon sp." Acta Veterinaria Hungarica 55, no. 4 (2007): 525–32. http://dx.doi.org/10.1556/avet.55.2007.4.11.

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A Lippizan mare aborted a male fetus a few days before the expected foaling date without showing any clinical sings. Focal lympho-histiocytic hepatitis in the foal and multiplex focal lympho-histiocytic villitis accompanied by villus necroses and marked hypertrophy of chorionic epithelial cells in the arcades were observed. Elongated nucleated organisms were seen in groups in vacuoles or solitarily located in the cytoplasm of the chorionic epithelial cells. The organisms were in large numbers and often extracellularly in areas of villitis and villus necroses. They were Gram-positive, stained w

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Jo, Jaemin, Heung Up Kim, and Sang Taek Heo. "A Case of Gastric Syphilis Diagnosed by PCR Test: A Case Report." Journal of Medicine and Life Science 11, no. 1 (2014): 43–47. http://dx.doi.org/10.22730/jmls.2014.11.1.43.

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Syphilis is chronic and systemic inflammation caused by T. pallidum infection. Because the diagnosis is exclusively dependedon histology, its diagnosis could be very difficult in the patients without positive biopsy finding. We experienced a case ofgastric syphilis diagnosed by polymerase chain reaction (PCR) in case of biopsy negative patients. So we report this simplemethod to diagnose gastric syphilis that failed to show spirochetes on histology. A 70 year-old man visited our hospital viaprivate clinic with suspicious gastric malignancy finding on gastroscopy. Our gastroscopy showed the cha

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Belsito, Alphonso, Ivan Rascon-Aguilar, Jennifer Faircloth, Manuel Rodriguez, John Roddenberry, and Carlos Montero. "PCR/DNA Analysis (TZAM) Can Diagnose H. pylori Gastric Infection When Warthin Starry (WS) Silver Stain Is Negative." American Journal of Gastroenterology 106 (October 2011): S535—S536. http://dx.doi.org/10.14309/00000434-201110002-01398.

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18

Burmeister, Veronika, Paul D. Millikin, and John J. Taraska. "A TEM and SEM Study of Campylobacter pylori-like organisms in the human stomach." Proceedings, annual meeting, Electron Microscopy Society of America 47 (August 6, 1989): 1060–61. http://dx.doi.org/10.1017/s0424820100157280.

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Since the studies of Warren (1) and Marshall (2) in 1983, Campylobacter pylori has been isolated with increasing frequency from the human stomach. This spiral organism is located primarily on the surface epithelium, and is very common in cases of active chronic gastritis (6). These findings have led to the exciting speculation that some ulcers, at least, may be secondary to infectious disease, and therefore amenable to antimicrobial treatment.The specimen described here is from an 80-year old Caucasian male who was originally admitted to the hospital for arthritis and diabetic neuropathy. Howe

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Mete, Aslı, Andrea Eigenheer, Andrea Goodnight, and Leslie Woods. "Clostridium piliforme encephalitis in a weaver bird (Ploceus castaneiceps)." Journal of Veterinary Diagnostic Investigation 23, no. 6 (2011): 1240–42. http://dx.doi.org/10.1177/1040638711425594.

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A juvenile Taveta golden weaver ( Ploceus castaneiceps) bird housed in a zoo aviary developed a sudden onset of neurological signs. The bird demonstrated head tilt, rolling onto its back, and inability to perch. Euthanasia was elected due to lack of response to intensive care, and a necropsy was performed. There were no significant abnormal findings on gross examination. On histopathology, the remarkable findings were localized to the brain and consisted of multifocal cerebral microabscesses and rarefaction. Filamentous rod-shaped bacteria were present within and at the periphery of the necrot

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Brito, T. de, Marina P. Sandoval, Ana G. Silva, R. C. Saad, and W. Colaiacovo. "Intestinal spirochetosis: first cases reported in Brazil and the use of immunohistochemistry as an aid in histopathological diagnosis." Revista do Instituto de Medicina Tropical de São Paulo 38, no. 1 (1996): 45–53. http://dx.doi.org/10.1590/s0036-46651996000100009.

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Colonization of the colon and rectum by intestinal spirochetes is detected for the first time in Brazil in 4 of 282 (1.41%) patients who had undergone sigmoidoscopy and/or colonoscopy with a histopathological diagnosis of chronic non specific-colitis. This frequency is probably understimated, since surgically obtained specimens were not considered in the present study. Histopathological diagnosis was performed using routine stains like hematoxylin-eosin which showed the typical, of 3-µm thick hematoxyphilic fringe on the brush border of the surface epithelium, and by silver stains like the War

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Hamir, A. N., D. Trott, M. Palmer, and J. Stasko. "Naturally Occurring Spirochetes in the Colonic Mucosa of Raccoons (Procyon lotor)." Veterinary Pathology 38, no. 2 (2001): 233–36. http://dx.doi.org/10.1354/vp.38-2-233.

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The large intestines of 21 raccoons ( Procyon lotor; 11 wild caught, 10 laboratory confined) were examined for the presence of intestinal spirochetes. Light microscopy of sections stained with hematoxylin and eosin and Warthin-Starry stain showed the presence of spiral shaped organisms deep within the lumina of intestinal glands at the ileocolonic junction of 16 raccoons (76% prevalence). All laboratory-confined, grouphoused raccoons harbored the organisms, but only 6/11 (55% prevalence) live-trapped raccoons were positive for these spirochetes. The organisms were free in the glandular lumina,

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Masege, S. D., and A. Karstaedt. "A rare case of a chronic syphilitic gumma in a man infected with human immunodeficiency virus." Journal of Laryngology & Otology 128, no. 6 (2014): 557–60. http://dx.doi.org/10.1017/s0022215114001200.

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AbstractObjective:This paper reports a rare case of a human immunodeficiency virus infected man with gummatous syphilis of the face.Case report:A 39-year-old man presented with an ulcer of the face which had been slowly progressive over the previous 6 years. Examination showed an ulcerative lesion of the midface involving the cheeks, and completely destroying the nose, the upper lip and part of the lower lip. The teeth and gums were exposed. The ulcer had a moist, purulent base with rolled edges. The patient had human immunodeficiency virus, with a cluster of differentiation 4 count of 641 cel

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Poonacha, K. B., J. M. Donahue, R. C. Giles, et al. "Leptospirosis in Equine Fetuses, Stillborn Foals, and Placentas." Veterinary Pathology 30, no. 4 (1993): 362–69. http://dx.doi.org/10.1177/030098589303000405.

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Leptospirosis was diagnosed in 51 equine fetuses and 16 stillborn foals with gestational ages from 3½ to 11 months. Diagnosis was based on one or more of the following: positive fetal antibody titer, positive fluorescent antibody test, demonstration of spirochetes in kidney and/or placental sections stained by the Warthin-Starry technique, high leptospiral titers in aborting mares, or isolation of Leptospira spp. from fetal organs. Gross lesions were observed in 80.3% of the fetuses, stillborn foals, and placentas. Gross placental lesions included nodular cystic allantoic masses, edema, areas

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Kent, ML, V. Rantis, JW Bagshaw, and SC Dawe. "Enhanced detection of Enterocytozoon salmonis (Microspora), an intranuclear microsporean of salmonid fishes, with the Warthin-Starry stain combined with hematoxylin and eosin." Diseases of Aquatic Organisms 23 (1995): 235–37. http://dx.doi.org/10.3354/dao023235.

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Loeb, Mark B., Robert H. Riddell, Cindy James, Richard Hunt, and Fiona M. Smaill. "Evaluation of Salivary Antibodies to Detect Infection with Helicobacter pylori." Canadian Journal of Gastroenterology 11, no. 5 (1997): 437–40. http://dx.doi.org/10.1155/1997/294081.

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Helicobacter pylori infection is an important cause of peptic ulcer disease and chronic gastritis. Infection with this bacterium stimulates the production of immunoglobulin (Ig) G antibody. Salivary IgG antibody tests to detect H pylori infection offer a convenient and noninvasive method of diagnosis. To evaluate an IgG salivary antibody kit, saliva was collected from 157 out-patients with dyspepsia referred for endoscopy to a tertiary centre. A salivary IgG ELISA antibody assay was performed using the Helisal Helicobacter pylori (IgG) assay kit, and at least four gastric biopsies were obtaine

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Castellano-Pellicena, Irene, Ciaran G. Morrison, Mike Bell, Clare O’Connor, and Desmond J. Tobin. "Melanin Distribution in Human Skin: Influence of Cytoskeletal, Polarity, and Centrosome-Related Machinery of Stratum basale Keratinocytes." International Journal of Molecular Sciences 22, no. 6 (2021): 3143. http://dx.doi.org/10.3390/ijms22063143.

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Melanin granules cluster within supra-nuclear caps in basal keratinocytes (KCs) of the human epidermis, where they protect KC genomic DNA against ultraviolet radiation (UVR) damage. While much is known about melanogenesis in melanocytes (MCs) and a moderate amount about melanin transfer from MC to KC, we know little about the fate of melanin once inside KCs. We recently reported that melanin fate in progenitor KCs is regulated by rare asymmetric organelle movement during mitosis. Here, we explore the role of actin, microtubules, and centrosome-associated machinery in distributing melanin withi

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Ackermann, Kerstin, Rebecca Kenngott, Monica Settles, Hartmut Gerhards, Johann Maierl, and Bettina Wollanke. "In Vivo Biofilm Formation of Pathogenic Leptospira spp. in the Vitreous Humor of Horses with Recurrent Uveitis." Microorganisms 9, no. 9 (2021): 1915. http://dx.doi.org/10.3390/microorganisms9091915.

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Equine recurrent uveitis (ERU) causes painful inflammatory attacks and oftentimes blindness in the affected eyes. The disease is considered a late sequela of systemic leptospirosis. The most effective therapy is the surgical removal of the vitreous (vitrectomy), which is not only therapeutic, but provides vitreous material that can be assessed diagnostically. For example, the lipL32 gene, culturable Leptospira spp., and anti-Leptospira antibodies have all been detected in vitreous samples obtained from eyes with chronic ERU. Despite this clear evidence of leptospiral involvement, the systemic

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Ramírez-Amador, Velia, Gabriela Anaya-Saavedra, Brenda Crabtree-Ramírez, Lilly Esquivel-Pedraza, Marcela Saeb-Lima, and Juan Sierra-Madero. "Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients." Journal of Sexually Transmitted Diseases 2013 (December 17, 2013): 1–8. http://dx.doi.org/10.1155/2013/892427.

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Background. Oral lesions may constitute the first clinical manifestation in secondary syphilis, but detailed descriptions in HIV-infected individuals are scarce. Objective. To describe the clinical characteristics of oral secondary syphilis in HIV-infected patients and its relevance in the early diagnosis of syphilis. Methods. Twenty HIV/AIDS adult subjects with oral secondary syphilis lesions presenting at two HIV/AIDS referral centers in Mexico City (2003–2011) are described. An oral examination was performed by specialists in oral pathology and medicine; when possible, a punch biopsy was do

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Paranhos, J. E. S., J. S. Leite, M. G. G. Souza, F. G. F. Padilha, D. A. Sousa, and A. M. R. Ferreira. "Conventional diagnostic methods and immunohistochemistry in the detection of gastric Helicobacter species in dogs with chronic gastropathy." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 75, no. 6 (2023): 1039–46. http://dx.doi.org/10.1590/1678-4162-12911.

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ABSTRACT An accurate diagnostic test for Helicobacter spp. infection in dogs is necessary but no gold standard diagnostic method has yet been established. The purpose of this study was to assess the sensitivity of conventional diagnostic methods as opposed to immunohistochemistry (IHC) in the detection of Helicobacter spp. in gastric samples of dogs with chronic gastropathy. Samples of gastric fundus, body and antrum were collected by gastroscopy from 13 domestic dogs presenting chronic vomit and submitted to the rapid urease test (RUT), cytopathology, histopathology with Hematoxylin-Eosin (HE

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Nai, Gisele Alborghetti, Ana Carolina Gomes Parizi, and Ricardo Luís Barbosa. "Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens." Arquivos de Gastroenterologia 44, no. 3 (2007): 240–43. http://dx.doi.org/10.1590/s0004-28032007000300012.

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BACKGROUND: Helicobacter pylori is the most prevalent infectious agent worldwide. About 90% of patients with chronic gastritis are infected with this bacterium. Some studies have shown a association between the H. pylori concentration and the scores of gastritis activity and severity. AIM: To evaluate the association between H. pylori concentration and the combining frequency of findings on histopathological examination. METHODS: Two hundred consecutive gastric endoscopic biopsies diagnosed as chronic gastritis were retrospectively investigated. The Warthin-Starry silver stain was used to stud

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Delvin, Edgard E., Jean L. Brazier, Collete Deslandres, Fernando Alvarez, Pierre Russo, and Ernest Seidman. "Accuracy of the [¹³C]‐Urea Breath Test in Diagnosing Helicobacter pylori Gastritis in Pediatric Patients." Journal of Pediatric Gastroenterology and Nutrition 28, no. 1 (1999): 59–62. http://dx.doi.org/10.1002/j.1536-4801.1999.tb02005.x.

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ABSTRACTBackground:The causal association between Helicobacter pylori (H. pylori) colonization of the gastric mucosa and gastritis is now well established. Histologic examination of endoscopic biopsy specimens has long been regarded as the gold standard for diagnosis. However, the changes can be focal in nature and presence of the organism may be missed in nonsampled areas. The urea breath test, which uses a stable isotope, offers distinct advantages, in that it is noninvasive and measures the activity of the micro‐organism. It thus represents a potentially invaluable tool in the initial diagn

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Ushio, Nanako, James K. Chambers, Ken-ichi Watanabe, et al. "Chronic Inflammatory and Proliferative Lesions of the Gallbladder in Aged Pigs." Veterinary Pathology 57, no. 1 (2019): 122–31. http://dx.doi.org/10.1177/0300985819875749.

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Primary epithelial tumors of the gallbladder are rarely reported in animals. In this study, 9 aged pigs (6–12 years old) were histopathologically examined for gallbladder proliferative lesions. At necropsy, a large gallstone occupied the lumen of the gallbladder of 3 pigs. Histopathological examination revealed chronic cholecystitis in all 9 pigs, mucosal hyperplasia in 2 pigs, adenoma in 1 pig, and adenocarcinoma in 2 pigs. Bacilli were detected in the gallbladder lumen of 6 pigs by Warthin-Starry stain. Mucosal hyperplasia, adenoma, and adenocarcinoma were characterized by papillary projecti

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Karim, Abdulkarim Jafar, and Zainab Majid Abbas. "Histopathology of the kidney and seroprevalence of leptospirosis in wild rats in Baghdad Province, Iraq." January-July 7, no. 1 (2021): 19–30. http://dx.doi.org/10.14202/ijoh.2021.19-30.

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Background and Aim: Leptospirosis, caused by pathogenic leptospires, is a globally emerging infectious disease affecting both humans and animals, which act as reservoirs, with large outbreaks worldwide. The role of rats in dispersing leptospirosis was never investigated in Iraq. Because of the seriousness of the disease and the scarce data regarding this disease in Iraq, this study determines the incidence of leptospirosis in rats and its renal histopathological profile. Materials and Methods: Of 211 captured rats, 82 apparently healthy rats were included in this study. After euthanatizing, 3-

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Jones, Gary F., Peter R. Davies, Rebecca Rose, Gilbert E. Ward, and Michael P. Murtaugh. "Comparison of techniques for diagnosis of proliferative enteritis of swine." American Journal of Veterinary Research 54, no. 12 (1993): 1980–85. http://dx.doi.org/10.2460/ajvr.1993.54.12.1980.

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Summary In an abattoir-based case-control study, histologic, and macroscopic examination of porcine intestines at slaughter and 2 molecular assays were compared for use as diagnostic tests of proliferative enteritis (pe). Fecal samples and intestinal specimens were collected from pigs with grossly thick ileum and from clinically normal pigs at slaughter. Tissue specimens were fixed in neutral buffered 10% formalin, and sectioned. Sections stained with H&E were examined for proliferative lesions by a pathologist unaware of the group to which the pig had been assigned on the basis of results

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Mitsui, Ikki, and Kazuyuki Uchida. "Canine Gallbladder Erosion/Ulcer and Hemocholecyst: Clinicopathological Characteristics of 14 Cases." Animals 13, no. 21 (2023): 3335. http://dx.doi.org/10.3390/ani13213335.

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(1) Background: Gallbladder mucosal erosion and/or ulceration are illnesses associated with unexpected gallbladder intra-cystic bleeding (hemocholecyst), an under-reported problem in dogs. (2) Methods: Clinicopathological characteristics of 14 dogs with gallbladder erosion/ulcer were investigated in this single-center retrospective study using clinical data and archived gallbladder tissues of client-owned dogs. (3) Results: Canine gallbladder erosion/ulcer tends to occur in older, neutered dogs of various breeds. Vomiting, lethargy, and anorexia are common. Concurrent gallbladder rupture occur

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Qureshi, T. Z., K. Saleem, R. Bilal, and S. Zafar. "GENERAL PREVALENCE OF HELICOBACTER PYLORI INFECTION IN DYSPEPTIC POPULATION OF ISLAMABAD, PAKISTAN." Nucleus 45, no. 3-4 (2020): 157–62. https://doi.org/10.71330/nucleus.45.03-4.991.

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Helicobacter pylori was known as campylobacter pyloridis in the beginning of the twentieth century. Doenges was the first to find this bacterium in the autopsy specimens of stomach using haematoxylin and eosin stains. In 1940 Freedburg and Baron carried out a study on 35 partial gastrectomy specimens and found spirochetes in 37% after a long search. A major breakthrough occurred with the advent of fibroptic biopsy technique permitting the biopsy of stomach. Then in 1975 Steer and Colin Jones observed gram negative bacilli in 80% of patients with gastric ulcer. The bacterium was closely associa

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Chan, Zhi En, and Jasmine Chung Shimin. "716. A Case of Symptomatic Intestinal Spirochetosis." Open Forum Infectious Diseases 7, Supplement_1 (2020): S409. http://dx.doi.org/10.1093/ofid/ofaa439.908.

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Abstract Background Intestinal spirochetosis (IS) is a condition caused by Brachyspira aalborgi and Brachyspira Pilosicoli. Its clinical significance has long been a point of contention with some debating that these spirochetes are simply colonic commensals. It is a condition that is more prevalent in developing nations as well as patients with HIV and the homosexual population. The epidemiology and prevalence of IS has not been studied in the local context. Methods We reviewed a case of a 37-year-old man who presented with a two month history of persistent lower abdominal pain, hematochezia,

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Sourabh, Das, Debnath Maharshi, Choudhury Arkadip, Majumder Nabaneet, Nath Sanjay, and Chakraborty Avik. "Clinicopathological Study of Helicobacter Pylori Infection in Patients with Acid Peptic Disorder Attending Tripura Medical College and Dr B.R.A.M Teaching Hospital." International Journal of Pharmaceutical and Clinical Research 15, no. 12 (2023): 1175–83. https://doi.org/10.5281/zenodo.11200144.

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<strong>Introduction:</strong> Acid peptic disorder (APD) is a global issue caused by imbalances in gastric secretions, leading to conditions like gastritis, ulcers, and duodenal ulcers. H. pylori, a Gram-negative bacterium, are a common human pathogen, colonizing 60% of the world’s population. It causes chronic inflammation in human gastric mucosa, leading to progressive damage to the stomach lining and various stomach diseases without treatment. This study aims to determine the prevalence of H. pylori infection in adult patients with APD symptoms, compare the sensitivity and speci

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Smith, B. C., and B. Salh. "A201 A CASE OF SYPHILIS MASQUARADING AS CROHN’S DISEASE." Journal of the Canadian Association of Gastroenterology 5, Supplement_1 (2022): 86–89. http://dx.doi.org/10.1093/jcag/gwab049.200.

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Abstract Background It is important for gastroenterologists to keep syphilis on their differential. We present a case of rectal syphilis initially misdiagnosed as Crohn’s disease with commensal intestinal spirochetosis. Aims This case highlights how rectal syphilis can present with endoscopic and clinical findings consistent with refractory inflammatory bowel disease. Methods Case report and literature review. Results A 58 healthy male was referred for flexible sigmoidoscopy after having increased frequency of bowel movements, up to 10 per day, with mucous secretions at times mixed with blood

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Zarrinkhoo, Erfan, Kyle D. Klingbeil, Shreya Condamoor, et al. "Multi-hospital retrospective study comparing gastric adenocarcinoma in Hispanic versus non-Hispanic patients." Journal of Clinical Oncology 41, no. 16_suppl (2023): e16027-e16027. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e16027.

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e16027 Background: Gastric cancer is one of the most prevalent malignancies in the United States and carries a particularly high rate of mortality. In the United States, the overall gastric cancer rate continues to decline amongst Caucasian and African American patients; however, it remains static amongst Hispanic patients. While numerous studies have been conducted to better understand the underlying causes leading to the disproportionate incidence of gastric cancer among Hispanics, it is still not well understood. This retrospective study sought to compare the clinicopathological features an

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Du, Jing, David Woolston, Kimberly Costas, Alexandre Hirayama, Cameron Turtle, and Cecilia Yeung. "642 Retrospective review of pulmonary pathology associated with chimeric antigen receptor T cell therapy." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A679. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0642.

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BackgroundChimeric antigen receptor (CAR) T-cell therapy is an immunotherapy which uses genetically modified T cells engineered to express CARs to recognize and kill cells that harbor specific antigens. CAR T-cell products designed to target the tumor specific antigens have been used for the treatment of relapse and/or refractory of acute lymphoblastic leukemia, non-Hodgkin lymphomas, myeloma, and solid tumor in clinical trials at our institution. Several side effects have been reported including increased risk of infection.MethodsRetrospective review of morphologic, microbiologic and flow cyt

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Maruma, F. "Pulse Treatment Using Azithromycin in HIV/AIDS-Associated Solitary Tumor-Like Bacillary Angiomatosis." Asploro Journal of Biomedical and Clinical Case Reports 3, no. 3 (2020): 217–20. https://doi.org/10.36502/2020/ASJBCCR.6215.

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With the advent of the HIV/AIDS pandemic within the South Saharan region, clinicians are faced with accentuated clinical presentations of previously well-known diseases. Bacillary angiomatosis is no exception to this rule. Bacillary angiomatosis is a cutaneous and systemic bacterial infection caused by gram-negative Bartonella species. We report a case of an immunocompromised 44 years old female patient who presented with a solitary tumor-like bacillary angiomatosis that was treated successfully with azithromycin in a bi-weekly pulsed dosing regimen. This patient had a considerably large (12 x

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Viegas de Carvalho, Leda, Filipe Soares Nogueira, Francisco Vale, et al. "Cervical Tuberculosis Mimicking Cervical Cancer in a Postmenopausal Woman: A Case Report." Acta Microbiologica Hellenica 70, no. 1 (2025): 1. https://doi.org/10.3390/amh70010001.

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Cervical tuberculosis is a rare form of genital tuberculosis. A case of a 73-year-old woman who presented with cervical wall thickening on magnetic resonance imaging, suggesting an invasive malignant neoplasm, is documented. Cervical cone excision was performed for histopathological study. Microscopy showed epithelioid granulomas, without appreciable caseous necrosis, in the wall of the uterine cervix, associated with erosion of the overlying cervical mucosa. Histochemical stains for microorganisms (Ziehl–Neelsen, Grocott, and Warthin–Starry) were negative. Immunohistochemistry for Treponema p

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Rodriguez, Bernardo J., Diego Aranzazu, Gloria E. Giraldo, Lyda C. Alvarez, Eliana M. Cano, and Bibiana Isaza. "Prevalencia de enteropatía proliferativa porcina y caracterización histopatológica de las lesiones asociadas en cerdos sacrificados en el Matadero Municipal de Medellín, Colombia." Revista Colombiana de Ciencias Pecuarias 17, no. 1 (2016): 11–19. http://dx.doi.org/10.17533/udea.rccp.323919.

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Resumen En el período comprendido entre julio y octubre del año 1997 se evaluaron 360 intestinos de cerdos sacrificados en el Matadero Municipal de Medellín, Colombia, con el objetivo de establecer la prevalencia de la Enteropatía Proliferativa Porcina (EPP) en el departamento de Antioquia, caracterizar las lesiones anatomopatológicas asociadas y determinar la presencia de su agente etiológico Lawsonia intracellularis. El cálculo de la muestra se efectuó de una población tabular infinita con un límite de confianza del 95% y una seguridad de ±5%. Las muestras obtenidas se sometieron a inspecció

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Wright, James R. "Aldred Scott Warthin." Archives of Pathology & Laboratory Medicine, January 27, 2021. http://dx.doi.org/10.5858/arpa.2020-0474-hp.

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Context.— Aldred Scott Warthin, MD, PhD, was professor of pathology and director of the pathological laboratory at the University of Michigan during the first third of the 20th century. Objective.— To explore the life and accomplishments of Dr. Warthin and his impact on academic anatomic and clinical pathology. Design.— Available primary and secondary historic sources were reviewed. Results.— After studying music, biology, and botany, Warthin attended medical school at the University of Michigan, graduating in 1891; he remained in Ann Arbor for 40 years, almost single-handedly transforming a r

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Garcia-Hernandez, David, Marti Vall-Mayans, Susanna Coll-Estrada, et al. "Human intestinal spirochetosis, a sexually transmissible infection? Review of six cases from two sexually transmitted infection centres in Barcelona." International Journal of STD & AIDS, November 24, 2020, 095646242095835. http://dx.doi.org/10.1177/0956462420958350.

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Human intestinal spirochetosis (HIS) is a possible cause of chronic diarrhoea and affects mainly men who have sex with men (MSM) and people living with HIV. Diagnosis is based on colon biopsy, where spirochetes can be observed on the luminal surface, especially with the Warthin-Starry stain or similar silver stains. We conducted a retrospective descriptive study of all HIS cases diagnosed in two sexually transmitted infections (STI) centres in Barcelona from 2009 until 2018. The medical histories were reviewed to gather epidemiological, clinical, and diagnostic variables. Six patients were dia

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Mbongo, William, Alvaro C. Laga, and Isaac H. Solomon. "Detection of Gram-positive and Gram-negative bacteria in brain abscesses by 16S rRNA in situ hybridization." Journal of Neuropathology & Experimental Neurology, November 7, 2024. http://dx.doi.org/10.1093/jnen/nlae118.

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Abstract In situ hybridization (ISH) staining of bacterial 16S ribosomal RNA (rRNA) is an alternative to standard histological stains (eg, Gram, Warthin-Starry), and may improve the diagnosis of bacterial brain abscesses. To evaluate the utility of 16S rRNA ISH, a 10-year retrospective cohort was assembled from a large academic medical center. Results of histological stains, cultures, and 16S rRNA sequencing were extracted from reports, and new Gram and 16S rRNA ISH stains were performed. Histologically identifiable bacteria were present in 40/63 (63%) cases and 38/57 (67%) were associated wit

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Shiga, Takanori, Yoko Kakinuma, Miu Takada, et al. "Chronic bronchitis and bronchiolitis with prominent globule leukocyte infiltration in a cat with Filobacterium felis." Veterinary Pathology, March 15, 2025. https://doi.org/10.1177/03009858251324646.

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A 7-year-old mixed-breed cat presented with intermittent dry cough for 2 years. Histological examination of the lung biopsy revealed hyperplasia of bronchial and bronchiolar epithelium, and intraepithelial infiltration of globule leukocytes in many bronchi, bronchioles, and terminal bronchioles. Lymphoid aggregates cuffed airways, respiratory bronchioles, and alveolar ducts. Terminal airway inflammation was associated with type II pneumocyte hyperplasia within adjacent alveoli. Warthin-Starry stain revealed numerous argyrophilic and filamentous bacilli that were interspersed or clustered with

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Villaverde, MD, Marian Rosel D., Juan Paolo David S. Villena, MD, and Claudine Yap Silva, MD. "A Peculiar Pattern: Nodular Secondary Syphilis with Granulomatous Dermatitis." Acta Medica Philippina 58, no. 17 (2024). http://dx.doi.org/10.47895/amp.v58i17.9040.

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Nodular syphilis with a granulomatous inflammatory histopathologic pattern is an uncommon cutaneous presentation of secondary syphilis which could pose a diagnostic challenge for clinicians and pathologists alike. A 33-year-old male diagnosed with HIV presented with a 5-week history of asymptomatic generalized erythematous papules and nodules with overlying scales, with involvement of the palms and soles. Histopathologic examination of a nodule from the forearm revealed non-caseating granulomas in a background of a mixed cell inflammatory infiltrate composed of lymphocytes, epithelioid and foa

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Azizi, Shahrzad, Reza Kheirandish, and Elham Rahimi. "Comparison of polymerase chain reaction and Warthin-Starry techniques to detect Leptospira spp. in kidneys of slaughtered cattle." Onderstepoort J Vet Res 81, no. 1 (2014). http://dx.doi.org/10.4102/ojvr.v81i1.821.

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Leptospirosis is a worldwide zoonotic disease that is caused by Gram-negative spirochaetes, Leptospira species. Affected animals excrete the organism in the urine into the environment and act as a source of infection. Cattle are maintenance hosts for some serovars of leptospirosis and are important in the transmission of the infection to humans. At post mortem examination, affected cattle show white spots in their kidneys but these are not specific for leptospirosis. Sometimes it is necessary that leptospirosis be diagnosed in the carcass. Different direct methods, including polymerase chain r

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