Academic literature on the topic 'Waters Acquity C18'

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Journal articles on the topic "Waters Acquity C18"

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Lavarello, Chiara, Sebastiano Barco, Martina Bartolucci, et al. "Development of an Accurate Mass Retention Time Database for Untargeted Metabolomic Analysis and Its Application to Plasma and Urine Pediatric Samples." Molecules 26, no. 14 (2021): 4256. http://dx.doi.org/10.3390/molecules26144256.

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Liquid-chromatography coupled to high resolution mass spectrometry (LC-HRMS) is currently the method of choice for untargeted metabolomic analysis. The availability of established protocols to achieve a high confidence identification of metabolites is crucial. The aim of this work is to describe the workflow that we have applied to build an Accurate Mass Retention Time (AMRT) database using a commercial metabolite library of standards. LC-HRMS analysis was carried out using a Vanquish Horizon UHPLC system coupled to a Q-Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer (Thermo Fisher
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Li, Yu, Qian Zhao, Pei Hu, and Ji Jiang. "CX1003 quantification by ultra-performance LC–MS/MS in human plasma and its application to a pharmacokinetic study in solid tumor patients." Bioanalysis 11, no. 16 (2019): 1483–93. http://dx.doi.org/10.4155/bio-2019-0096.

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Aim: CX1003 is a novel multitargeted receptor tyrosine kinase inhibitor targeting cancer patients with relapsed or metastatic malignant solid tumors. The study aimed to develop a robust and rapid assay approach to quantify CX1003 in human plasma. Methodology & results: Samples of plasma were purified by SPE where the diluted eluates were then separated by a Waters Acquity CSH C18 column and thereafter detected using positive electrospray ionization via an ultra performance LC–MS/MS. Conclusion: The method to quantify CX1003 in human plasma was first exploited and validated with good sensit
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Seo, Chang-Seob, and Hyeun-Kyoo Shin. "Simultaneous Determination of 12 Marker Components in Yeonkyopaedok-san Using HPLC–PDA and LC–MS/MS." Applied Sciences 10, no. 5 (2020): 1713. http://dx.doi.org/10.3390/app10051713.

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Yeonkyopaedok-san is a traditional Korean medicine used in the early treatment of boils. In the present study, its 12 marker components for quality control were determined using high-performance liquid chromatography (HPLC) with photodiode array detection and ultra-performance liquid chromatography–mass spectrometry with tandem mass spectrometry (UPLC–MS/MS). The investigated 12 marker components of Yeonkyopaedok-san were as follows: 3-caffeoylquinic acid, cimifugin 7-glucoside, liquiritin apioside, ferulic acid, narirutin, 5-O-methylvisammioside, naringin, neohesperidin, oxypeucedanin hydrate
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Lv, Dai Zhu, Zhu Zhu, Hong Qiu Yuan, and Jin Hui Luo. "Development and Validation of a Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Method for the Determination of Dimethomorph and Tebuconazole Residue in Soil." Applied Mechanics and Materials 522-524 (February 2014): 132–35. http://dx.doi.org/10.4028/www.scientific.net/amm.522-524.132.

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A liquid chromatographic-tandem mass spectrometric (LC-MS/MS) method for the simultaneous quantification and identification of dimethomorph and tebuconazole in soil has been developed and validated. The samples were pre-concentrated and purified using QuEChERS method extraction,which provided satisfactory results. The separation was performed on a Waters ACQUITY UPLC C18 column with a linear gradient of acetonitrile - water containing 5 mM ammonium acetate. The optimised method offered a good linear correlation (r2> 0.99), excellent precision (RSD < 4.0%) and preferable recovery (from 82
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Patel, A. J., N. K. Patel, A. J. Vyas, A. B. Patel, and A. I. Patel. "RP-UPLC Stability Indicating Assay Method for Simultaneous Estimation of Dextromethorphan Hydrobromide and Chlorpheniramine Maleate in Tablet Dosage Form." Asian Journal of Organic & Medicinal Chemistry 5, no. 3 (2020): 192–96. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p269.

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RP-UPLC method was developed and validated for the determination of chlorpheniramine maleate and dextromethorphan hydrobromide in tablet dosage form. Reverse phase waters acquity UPLC BEH C18 (50 mm × 2.1 mm, 1.7 μm) column using isocratic mobile phase of 0.5 mL 0.1% TFA (trifluroacetic acid) in H2O:CH3CN (70:30 %v/v). The flow rate was 0.2 mL/min and 252 nm wavelength use for detection on PDA detector. The retention time of chlorpheniramine maleate was 1.2 min and 2.2 min for dextromethorphan hydrobromide. Chlorpheniramine maleate and dextromethorphan hydrobromide was subjected to stress cond
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Yu, Ying, Jing Zhang, Bing Shao, Yongning Wu, Hejun Duan, and Hongtao Liu. "Development of a Simple Liquid Chromatography-Tandem Mass Spectrometry Method for Multiresidue Determination of Antifungal Drugs in Chicken Tissues." Journal of AOAC INTERNATIONAL 94, no. 5 (2011): 1650–58. http://dx.doi.org/10.5740/jaoacint.10-244.

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Abstract A method involving LC coupled with MS/MS (LC/MS/MS) was designed for simultaneous quantification of 10 antifungal drugs (voriconazole, griseofulvin, clotrimazole, bifonazole, econazole, ketoconazole, itraconazole, miconazole, terconazole, and fluconazole) in the liver and muscles of chickens. Homogenized tissue samples were extracted with acetonitrile and subsequently underwent freezing-delipidation. A Waters Acquity Ultra Performance LC BEH C18 column was used to separate the analytes, coupled with MS/MS using an electrospray ionization source. The accuracy of the method was confirme
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Nathi, Rathnakar, and Sankar D.G. "SIMULTANEOUS DETERMINATION OF BIOACTIVE CONSTITUENTS IN GARCINIA MORELLA USING UPLC-Q-TOF-MS." Indian Drugs 59, no. 03 (2022): 41–46. http://dx.doi.org/10.53879/id.59.03.12170.

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A simple, precise and robust UPLC-Q-TOF-MS method was developed for the quantification of four marker compounds, namely citric acid derivative, iso garcinol, garcinol and garcimultiflorone-A in Garcinia morella, in order to study the fragmentation pathways of four marker compounds. The developed method was validated according to ICH guidelines in terms of linearity, LOD and LOQ, precision and accuracy. Optimized chromatographic conditions were Waters Acquity BEH C18 (100 X 2.1mm, 1.9 m) column, flow rate of 0.6 mL min-1, 8.0 minutes run time and mobile phase being 0.1 % formic acid in water /
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Harahap, Yahdiana, and Innet Maysyarah. "ANALYTICAL VALIDATION OF CLOPIDOGREL IN HUMAN PLASMA THROUGH ULTRAHIGHPERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY." International Journal of Applied Pharmaceutics 9 (October 30, 2017): 163. http://dx.doi.org/10.22159/ijap.2017.v9s1.79_86.

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Objective: This study developed a sensitive, selective, and valid method for analyzing clopidogrel in human plasma using liquid chromatographytandemmass spectrometry (LC-MS/MS).Methods: The chromatography separation was performed on the waters ACQUITY UPLC Class BEH C18 1.7 μm (2.1 × 100 mm) column, consisting of0.1% formic acid in water and 0.1% formic acid in acetonitrile (30-70) as the mobile phase, and an isocratic elution with a flow rate of 0.2 mL/minutes.The mass detection was performed using a Waters Xevo TQD equipped with positive electrospray ionization in the multiple reaction monit
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Seo, Chang-Seob, and Hyeun-Kyoo Shin. "Development of a Reverse-Phase High-Performance Liquid Chromatography and Liquid Chromatography Tandem Mass Spectrometry Methods for Quality Control of Daegunjoong-Tang." Applied Sciences 11, no. 8 (2021): 3437. http://dx.doi.org/10.3390/app11083437.

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Daegunjoong-tang (DGJT) is an oriental medicine consisting of four medicinal herbs (Zingiber officinale Rosc., Panax ginseng C.A.Mey., Oryza sativa L., and Zanthoxylum schinifolium Sieb. et Zucc.) that is used to treat intestinal- and cancer-related diseases. In this study, a protocol for quality control of DGJT based on reverse-phase high-performance liquid chromatography (HPLC) and liquid chromatography tandem mass spectrometry (LC–MS/MS) analysis were developed. In HPLC analysis, the marker analytes (hyperoside, quercitrin, ginsenoside Rg1, and 6-gingerol) were separated, verified, and quan
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Seo, Chang-Seob, and Kwang-Hoon Song. "Phytochemical Characterization for Quality Control of Phyllostachys pubescens Leaves Using High-Performance Liquid Chromatography Coupled with Diode Array Detector and Tandem Mass Detector." Plants 11, no. 1 (2021): 50. http://dx.doi.org/10.3390/plants11010050.

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Phyllostachys pubescens leaves are cultivated in a number of Asian countries and have been used for antipyretic and diuretic effects since ancient times, especially in Korea. The purpose of this study was to develop and validate of analytical method for quality control of P. pubescens leaves using high-performance liquid chromatography with diode array detector (HPLC–DAD) and liquid chromatography with tandem mass spectrometry (LC–MS/MS) detection. HPLC–DAD analysis was conducted with a Gemini C18 column, and distilled water–acetonitrile (both with 0.1% (v/v) formic acid) mobile-phase system.
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Conference papers on the topic "Waters Acquity C18"

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Schrynemeeckers, Rick. "Acquire Ocean Bottom Seismic Data and Time-Lapse Geochemistry Data Simultaneously to Identify Compartmentalization and Map Hydrocarbon Movement." In Offshore Technology Conference. OTC, 2021. http://dx.doi.org/10.4043/30975-ms.

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Abstract Current offshore hydrocarbon detection methods employ vessels to collect cores along transects over structures defined by seismic imaging which are then analyzed by standard geochemical methods. Due to the cost of core collection, the sample density over these structures is often insufficient to map hydrocarbon accumulation boundaries. Traditional offshore geochemical methods cannot define reservoir sweet spots (i.e. areas of enhanced porosity, pressure, or net pay thickness) or measure light oil or gas condensate in the C7 – C15 carbon range. Thus, conventional geochemical methods ar
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Bravo, M. C., A. Cely, D. Xavier, et al. "A Novel Approach to Map Heavy Oil Viscosity from Standard Mud Gas – A Field Case from the Peregrino Field." In SPE Offshore Europe Conference & Exhibition. SPE, 2023. http://dx.doi.org/10.2118/215525-ms.

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Abstract Peregrino is a heavy oil field in the Campos basin offshore Brazil. The field started production in 2011, and Phase 2 was on stream in 2022. More development drilling is ongoing. The oil viscosity in Phase 2 has large variations from limited exploration wells, ranging from 30 to 180 cp. Any changes in the viscosity in the reservoirs can lead to a large difference in oil recovery. Therefore, updating the viscosity distribution in the reservoirs along with the development drilling is important. Different methods can acquire reservoir oil viscosity, including downhole logging and samplin
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Buckle, Philip Shane Gerard, Abdul Faiz Haji Abdullah, Nurhafizah Zaini, et al. "Utilization of Digitalized Numerical Model Derived From Advanced Mud Gas Data for Low Cost Fluid Phase Identification, Derisking Drilling and Effective Completion Plan in Depleted Reservoir." In 2022 SPWLA 63rd Annual Symposium. Society of Petrophysicists and Well Log Analysts, 2022. http://dx.doi.org/10.30632/spwla-2022-0092.

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The scope of this paper is to illustrate the successful application of the Advanced Mud Gas (AMG) analysis in oil rim development wells, in a large fault block reservoir offshore Brunei Darussalam, operated by Brunei Shell Petroleum (BSP). Developing thin oil rims is challenging as gas and water breakthrough can be very common and therefore the need to have an accurate fluid type identification is crucial for the subsequent completion. In this field, pressure depletion and wellbore instability posed serious concerns about the effectiveness of the traditional density-neutron tool to reliably id
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