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1

Meani, Paolo, Thijs Delnoij, Giuseppe M. Raffa, et al. "Protracted aortic valve closure during peripheral veno-arterial extracorporeal life support: is intra-aortic balloon pump an effective solution?" Perfusion 34, no. 1 (2018): 35–41. http://dx.doi.org/10.1177/0267659118787426.

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Background: Left ventricular (LV) afterload increase with protracted aortic valve (AV) closure may represent a complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). The aim of the present study was to assess the effects of an intra-aortic balloon pump (IABP) to overcome such a hemodynamic shortcoming in patients submitted to peripheral V-A ECMO. Methods: Among 184 adult patients who were treated with peripheral V-A ECMO support at Medical University Center Maastricht Hospital between 2007 and 2018, patients submitted to IABP implant for protracted AV closure after V-A E
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2

Atrakchi, A., S. D. Gray, and R. C. Carlsen. "Development of soleus muscles in SHR: relationship of muscle deficits to rise in blood pressure." American Journal of Physiology-Cell Physiology 267, no. 3 (1994): C827—C835. http://dx.doi.org/10.1152/ajpcell.1994.267.3.c827.

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Skeletal muscles from 24- to 28-wk-old spontaneously hypertensive rats (SHR) exhibit decreased contractile capacity and resistance to fatigue. The present study was designed to determine the age at which these deficits first appear and their relationship to the development and progression of the rise in blood pressure. SHR soleus was significantly weaker than age-matched Wistar-Kyoto (WKY) soleus at all ages studied, but resistance to fatigue varied with age. Soleus muscles in 6- to 8-wk-old SHR were, on average, more fatigue resistant than age-matched WKY muscles. Fatigue resistance in 16- to
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3

Fujii, Yutaka, Nobuo Akamatsu, Yasunori Yamasaki, et al. "Development of a Pulsatile Flow-Generating Circulatory Assist Device (K-Beat) for Use with Veno-Arterial Extracorporeal Membrane Oxygenation in a Pig Model Study." Biology 9, no. 6 (2020): 121. http://dx.doi.org/10.3390/biology9060121.

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Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) preserves the life of heart failure patients by providing an adequate oxygen supply and blood flow to vital organs. For patients with severe cardiogenic shock secondary to acute myocardial infarction or acute myocarditis, V-A ECMO is commonly used as the first choice among cardiac circulatory support devices. While V-A ECMO generates circulatory flow using a centrifugal pump, the provision of pulsatile flow is difficult. We previously reported our development of a new circulatory flow assist device (K-beat) for cardiac management wit
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4

de Trizio, Ignazio, Mariella Errede, Antonio d'Amati, Francesco Girolamo, and Daniela Virgintino. "Expression of P-gp in Glioblastoma: What we can Learn from Brain Development." Current Pharmaceutical Design 26, no. 13 (2020): 1428–37. http://dx.doi.org/10.2174/1381612826666200318130625.

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P-Glycoprotein (P-gp) is a 170-kDa transmembrane glycoprotein that works as an efflux pump and confers multidrug resistance (MDR) in normal tissues and tumors, including nervous tissues and brain tumors. In the developing telencephalon, the endothelial expression of P-gp, and the subcellular localization of the transporter at the luminal endothelial cell (EC) plasma membrane are early hallmarks of blood-brain barrier (BBB) differentiation and suggest a functional BBB activity that may complement the placental barrier function and the expression of P-gp at the blood-placental interface. In earl
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5

Botterbusch, C. N., P. Monticone, and L. Polverelli. "Flow Performance of the CorWave LVAD Membrane Wave Pump." Journal of Heart and Lung Transplantation 37, no. 4 (2018): S259. http://dx.doi.org/10.1016/j.healun.2018.01.648.

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6

Lei, U., C. W. Huang, James Chen, et al. "A travelling wave dielectrophoretic pump for blood delivery." Lab on a Chip 9, no. 10 (2009): 1349. http://dx.doi.org/10.1039/b822809d.

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7

Griff, E. R., Y. Shirao, and R. H. Steinberg. "Ba2+ unmasks K+ modulation of the Na+-K+ pump in the frog retinal pigment epithelium." Journal of General Physiology 86, no. 6 (1985): 853–76. http://dx.doi.org/10.1085/jgp.86.6.853.

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This paper presents electrophysiological evidence that small changes in [K+]o modulate the activity of the Na+-K+ pump on the apical membrane of the frog retinal pigment epithelium (RPE). This membrane also has a large relative K+ conductance so that lowering [K+]o hyperpolarizes it and therefore increases the transepithelial potential (TEP). Ba2+, a K+ channel blocker, eliminated these normal K+-evoked responses; in their place, lowering [K+]o evoked an apical depolarization and TEP decrease that were blocked by apical ouabain or strophanthidin. These data indicate that Ba2+ blocked the major
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8

Scolletta, Sabino, Igor D. Gregoric, Luigi Muzzi, Branislav Radovancevic, and O. Howard Frazier. "Pulse wave analysis to assess systemic blood flow during mechanical biventricular support." Perfusion 22, no. 1 (2007): 63–66. http://dx.doi.org/10.1177/0267659106074784.

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Measurement of systemic blood flow is of crucial importance in patients on mechanical circulatory support (MCS). We reported the case of a 65-year-old female patient in severe cardiogenic shock undergoing left (Jarvik 2000 axial flow pump) and right (Levitronix-Centrimag centrifugal pump) ventricular assist device implant. Evaluation of blood flow was obtained by ultrasonic flowmetry, continuous thermodilution technique, and pressure recording analytical method (PRAM). This pulse contour system allows beat-by-beat systemic blood flow assessment from the analysis of radial artery pressure wavef
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9

Mickleborough, Lynda L., George Arnold, and Ray C.-J. Chiu. "Complement consumption during cardiopulmonary bypass: bubble versus membrane oxygenators." Perfusion 1, no. 4 (1986): 261–69. http://dx.doi.org/10.1177/026765918600100405.

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The purpose of this study was to compare levels of C3 and C4 during cardiopulmonary bypass, using bubble and membrane oxygenators. In vitro studies were performed using human blood in a simple circuit involving an oxygenator, roller pump and connector tubing. In vivo studies were carried out in two separate institutions using a variety of bubble and membrane oxygenators. Samples were taken throughout the pump run (30-1 20 minutes). Complement levels were corrected for haemodilution. All oxygenators tested caused a rapid decrease in C3 and C4 complement levels on institution of bypass. The magn
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10

Snyder, Edward J., Sean Weckerly, Larry Gross, Melvin Velez, and Ira S. Tackel. "A Negative Pressure Alarm for Use in Neonatal Extracorporeal Membrane Oxygenation." Journal of ExtraCorporeal Technology 20, no. 2 (1988): 63–66. http://dx.doi.org/10.1051/ject/198820263.

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(J. Extra-Corpor. Technol. 20(2):63–66) The following is a design for a simple, inexpensive negative pressure alarm, with specific applications in neonatal Extracorporeal Membrane Oxygenation (ECMO). In a typical roller pump driven ECMO system, if the pump flow rate exceeds the heart’s venous return, or if for any reason there is insufficient blood flow into the tubing system, the negative pressure alarm disables the pump and activates alarms. The unavailability of such a modular device, through commercial manufacturers, has facilitated the need for ECMO centers to fabricate their own alarm sy
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11

Isaeva, M. S., A. I. Petrov, and Ye P. Banin. "Influence of the extracorporeal membrane oxygenation system centrifugal pump operation mode on blood damage." Omsk Scientific Bulletin. Series Aviation-Rocket and Power Engineering 8, no. 4 (2024): 46–53. https://doi.org/10.25206/2588-0373-2024-8-4-46-53.

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One of the key tasks in the development of mechanical circulatory support pump is to take into account its interaction with blood components and their corresponding damage. Within the framework of this study, numerical modeling of the pump operation in different modes is carried out and an assessment of the corresponding change in the values of hemolysis and thrombosis is made. It is found that the most dangerous operating modes also change depending on the parameter under consideration: hemolysis demonstrated the greatest dependence on rotation rate, thrombosis — on flow rate. It is also note
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12

Patel, Krishna, and Akif Ündar. "Centrifugal Pump Generates Superior Hemodynamic Performance Compared to a new Diagonal Blood Pump in Neonatal and Pediatric ECMO Circuits." World Journal for Pediatric and Congenital Heart Surgery 13, no. 2 (2022): 235–41. http://dx.doi.org/10.1177/21501351211057426.

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Purpose With newer generation diagonal and centrifugal blood pumps gaining popularity, the objective of this study was to compare the DP3-i-cor diagonal and RotaFlow centrifugal pumps in terms of hemodynamic performance using simulated neonatal and pediatric extracorporeal membrane oxygenation (ECMO) circuits. Description The DP3-i-cor diagonal pump is a part of the newly FDA-approved NovaLung system. The experimental circuit consisted of either the DP3-i-cor diagonal or RotaFlow centrifugal pump, a polymethylpentene membrane oxygenator, neonatal and pediatric arterial/venous cannulae, and 1/4
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13

YUN, ZHONG, CHUANG XIANG, and LIANG WANG. "EFFECT OF A HIGH-FREQUENCY VIBRATION BOUNDARY ON RBC." Journal of Mechanics in Medicine and Biology 18, no. 08 (2018): 1840032. http://dx.doi.org/10.1142/s0219519418400328.

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The vibrations in blood pumps were often caused by high speed, suspension structure, viscoelastic implantation environment and other factors in practical application. Red blood cell (RBC) was modeled using a nonlinear spring network model. The immersed boundary-lattice Boltzmann method (IB-LBM) was used to investigate the impact of high-frequency vibration boundary on RBC. To confirm the RBC model, the simulation results of RBC stretching were compared with experimental results. We examined the force acting on RBC membrane nodes; moreover, we determined whether RBC energy was affected by diffe
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14

Wahba, A., A. Philip, MF Bauer, M. Kaiser, H. Aebert, and DE Birnbaum. "The blood saving potential of vortex versus roller pump with and without aprotinin." Perfusion 10, no. 5 (1995): 333–41. http://dx.doi.org/10.1177/026765919501000509.

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To evaluate the potential of centrifugal blood pumps for saving blood, 120 patients scheduled for elective coronary artery bypass grafting were entered into a prospective randomized trial. A standard roller pump (group I) was compared with a centrifugal blood pump (group II) and roller pump plus aprotinin (group III). There was no significant difference between groups I and I I with respect to free haemoglobin, lactic dehydrogenase, serum bilirubin, platelet surface glycoprotein IIb-IIIa and granule membrane protein 140, chest-tube drainage, use of blood products, length of stay in intensive c
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15

Broman, Lars Mikael, Christer Eriksson, Björn Frenckner, and Kenneth Palmér. "Introducing the Loop for Circuit Access during Extracorporeal Membrane Oxygenation: Feasibility and Safety." Journal of ExtraCorporeal Technology 51, no. 3 (2019): 175–78. http://dx.doi.org/10.1051/ject/201951175.

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In extracorporeal membrane oxygenation (ECMO), blood is drained from the patient, and pumped through a membrane oxygenator/lung (ML) for gas exchange and then back to the patient. For monitoring blood gases, samples may be sampled downstream from the ML. This exposes the patient for embolization risk (air/clot) when the stopcocks are flushed. For safe sampling procedures, the Loop was introduced. It is a constant low-flow arteriovenous shunt (AVS) used preferably in venoarterial ECMO. It is composed of three different length and diameter three-way stopcocks connected to the circuit just downst
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16

Mellgren, K., L. G. Friberg, T. Hedner, G. Mellgren, and H. Wadenvik. "Blood Platelet Activation and Membrane Glycoprotein Changes during Extracorporeal Life Support (Ecls). In Vitro Studies." International Journal of Artificial Organs 18, no. 6 (1995): 315–21. http://dx.doi.org/10.1177/039139889501800604.

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The aim of this study was to evaluate an in vitro model for investigation of platelet function parameters in an extracorporeal system. Two different perfusion pumps were compared, a roller pump (Polystan) and a centrifugal pump (Biomedicus). A continuous increase in glycoprotein (GP)1b-negative platelets was observed in both circuits. A marked increase of plasma β-thromboglobulin thromboglobulin concentration and a decrease of the intracellular pool of serotonin was observed, indicating a marked release of alpha as well as of dense granules. The plasma concentration of glycocalicin increased i
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17

Alekyan, B. G., N. G. Karapetyan, A. Ya Novak, G. P. Plotnikov, Yu B. Knysh, and G. S. Grigoryan. "The clinical case of the first high risk percutaneus coronary intervention under use of the PulseCath iVAC 2L left ventricular assist device in Russia." Complex Issues of Cardiovascular Diseases 9, no. 1 (2020): 103–9. http://dx.doi.org/10.17802/2306-1278-2020-9-1-103-109.

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Percutaneous left ventricular assist devices are necessary to maintain blood circulation in patients with cardiogenic shock after high risk percutaneous coronary interventions. The PulseCath iVAC 2L is a new device that can be implanted percutaneously via the femoral artery. The device consists of an extracorporeal membrane pump and a catheter, which is inserted into the left ventricle through the aorta. The pump is connected to the console of the intra-aortic balloon counterpulsator generating a pulsatile blood flow.
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18

Ito, Takahiro, Takashi Ota, Rei Kono, et al. "Pump-Free Microfluidic Hemofiltration Device." Micromachines 12, no. 8 (2021): 992. http://dx.doi.org/10.3390/mi12080992.

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Hemofiltration removes water and small molecules from the blood via nanoporous filtering membranes. This paper discusses a pump-free hemofiltration device driven by the pressure difference between the artery and the vein. In the design of the filtering device, oncotic pressure needs to be taken into consideration. Transmembrane pressure (TMP) determines the amount and direction of hemofiltration, which is calculated by subtracting the oncotic pressure from the blood pressure. Blood pressure decreases as the channels progress from the inlet to the outlet, while oncotic pressure increases slight
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19

Wright, Gordon. "Factors affecting the pulsatile hydraulic power output of the Stockert roller pump." Perfusion 4, no. 3 (1989): 187–95. http://dx.doi.org/10.1177/026765918900400304.

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A detailed assessment of the hydraulic power output of the Stockert roller pump was performed with the pump operating in its 'pulsatile' mode. Pressure and flow waveforms and the pulsatile power generated in a model of the human vascular bed were dependant upon the pump output, the pump control settings and the diameters of the arterial line, the pump insert and aortic cannula. The pulsatile power output was lower when a silicone rubber pump insert was used rather than a polyvinyl chloride insert. The incorporation of a Cobe CML flat-sheet membrane oxygenator into the arterial line reduced the
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20

Valenzuela, Maria-Pau, Jaume Almirall, and María-José Amengual. "Membrane Bioincompatibility and Ultrafiltration Effects on Pulse Wave Analysis during Haemodialysis." ISRN Nephrology 2013 (December 17, 2013): 1–4. http://dx.doi.org/10.5402/2013/892315.

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Membrane bioincompatibility was demonstrated by successive white blood cell counts and C3a generation. Pulse wave analysis was obtained by applanation tonometry (SphygmoCor) in a sequential way: basal, after 30 minutes with nul ultrafiltration, and after a complete dialysis with ultrafiltration. At 15 minutes of haemodialysis, significant decrease in leukocyte count occurred: versus (), while C3a levels sharply increased from to ng/mL (). No changes were observed in augmentation index without ultrafiltration: versus . Only aortic systolic blood pressure was lower at 15 minutes: versus mmHg (),
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21

Zhi, Chao, Tadahiko Shinshi, and Minoru Uehara. "A Valveless MEMS Pump Utilizing a Thin Film Permanent Magnet." Key Engineering Materials 523-524 (November 2012): 551–56. http://dx.doi.org/10.4028/www.scientific.net/kem.523-524.551.

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A valveless MEMS pump utilizing a multi-layer thin film NdFeB/Ta permanent magnet (TFPM) has been presented. The MEMS pump consists of a diaphragm actuator utilizing 6μm in thickness and 3 mm in diameter TFPM which is bonded on a membrane made of polydimethylsiloxane (PDMS) of about 80μm thickness, a pump chamber and a pair of diffuser elements. TFPM is sputtered on a 50μm thick Nb sheet. The diffuser elements are used to generate a one-way fluid flow. The chamber is made of acryl plates. UV negative film resist is used to bond different layers. Applying amplitude of ±7.5V square wave voltage,
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22

Julien, J. L., and J. M. Frachisse. "Involvement of the proton pump and proton conductance change in the wave of depolarization induced by wounding in Bidens pilosa." Canadian Journal of Botany 70, no. 7 (1992): 1451–58. http://dx.doi.org/10.1139/b92-183.

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The role of protons in the slow wave of depolarization induced by wounding in Bidens pilosa L. was studied by means of voltage measurements performed under differing extracellular conditions. The degree of depolarization caused by an extracellular pH acidification from 7 to 4 was different when performed either in the resting conditions or 20 min after eliciting the slow wave. In the presence of cyanide, a heat stimulation still induced a slow wave, the amplitude of which was reduced to 42% of the control. While cyanide remained in the perfusing medium, the membrane did not repolarize. An extr
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23

Bearss, Mark G. "The Relationship Between Membrane Oxygenator Blood Path Pressure Drop and Hemolysis: An In-vitro Evaluation." Journal of ExtraCorporeal Technology 25, no. 3 (1993): 87–92. http://dx.doi.org/10.1051/ject/199325387.

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Plasma hemoglobin (pl-Hgb) production was measured for the Bard HF-5000 (n = 4), Sarns SMO (n =4) and Sarns Turbo (n =4) membrane oxygenators (MO), which were tested on separate closed-loop roller pump circuits to compare differences in hemolysis production as a function of pressure drop (P). The three oxygenators were selected because of their varied P characteristics. Circuits were prepared by clamping off the MO and then priming with freshly drawn, heparinized, filtered bovine blood that had an adjusted hemoglobin (Hgb) of 8.0 g/dL. Roller pump occlusions were set using a pressure transduce
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24

Waldenberger, F. R., E. Vandezande, P. Janssens, et al. "A New Pneumatic Pump for Extracorporeal Circulation: TPP (True Pulsatile Pump). Experimental and First Clinical Results." International Journal of Artificial Organs 20, no. 8 (1997): 447–54. http://dx.doi.org/10.1177/039139889702000807.

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A pulsatile, membrane type pump, TPP, was developed for use in routine cardiac surgery. The artificial ventricle consists of a polycarbonate housing with an inlet and outlet polyurethane tricuspid valve. The membrane is actuated hydraulically. For pre-clinical studies, we designed a study in sheep. After a pump run of 6 hours the animals were allowed to recover and sacrificed after 72 hours. All clinical parameters returned to normal values (p>0.05 vs. control values). During pump run we found elevated free plasma hemoglobine. However, these values returned to normal until the end of the ob
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25

Tracy, Thomas F. "New neonatal extracorporeal membrane oxygenation circuit with a self-regulating blood pump." Journal of Pediatric Surgery 29, no. 11 (1994): 1505. http://dx.doi.org/10.1016/0022-3468(94)90157-0.

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26

Gassner, B., S. Luterbacher, H. J. Schatzmann, and A. Wüthrich. "Dependence of the red blood cell calcium pump on the membrane potential." Cell Calcium 9, no. 2 (1988): 95–103. http://dx.doi.org/10.1016/0143-4160(88)90029-2.

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27

Lu, Pong-Jeu, Chi-Fu Jeffrey Yang, Meng-Yu Wu, Chun-Hao Hung, Ming-Yao Chan, and Tzu-Cheng Hsu. "Wave intensity analysis of para-aortic counterpulsation." American Journal of Physiology-Heart and Circulatory Physiology 302, no. 7 (2012): H1481—H1491. http://dx.doi.org/10.1152/ajpheart.00551.2011.

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Wave intensity analysis (WIA) was used to delineate and maximize the efficacy of a newly developed para-aortic blood pump (PABP). The intra-aortic balloon pump (IABP) was employed as the comparison benchmark. Acute porcine experiments using eight pigs, randomly divided into IABP ( n = 4) and PABP ( n = 4) groups, were conducted to compare the characteristics of intra- and para-aortic counterpulsation. We measured pressure and velocity with probes installed in the left anterior descending coronary artery and aorta, during and without PABP assistance. Wave intensity for aortic and left coronary
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28

Contento, Carlo, Andrea Battisti, Bruno Agrò, et al. "A novel veno-arteriovenous extracorporeal membrane oxygenation with double pump for the treatment of Harlequin syndrome." Perfusion 35, no. 1_suppl (2020): 65–72. http://dx.doi.org/10.1177/0267659120908409.

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Objectives: The Harlequin syndrome is a complication observed in patients receiving peripheral venoarterial extracorporeal membrane oxygenation. This condition is defined as a critical variation in the oxygen saturation between the upper and the lower part of the body deriving from a poor lung function. Methods: Between July 2018 and November 2019, a total of 60 patients (42 men and 18 women; mean age 57.4 ± 10.0 years; range = 28-71 years) underwent peripheral venoarterial extracorporeal membrane oxygenation in our center. Harlequin syndrome was identified in eight cases (six men and two wome
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29

Hara, Shintaro, and Takashi Isoyama. "The Current Status and Issue of the Blood Pump for Extracorporeal Membrane Oxygenator." MEMBRANE 44, no. 6 (2019): 306–10. http://dx.doi.org/10.5360/membrane.44.306.

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30

Hamadiche, M., and N. Kizilova. "A membrane model for wave flow in the blood vessels." Journal of Biomechanics 39 (January 2006): S608. http://dx.doi.org/10.1016/s0021-9290(06)85525-9.

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31

VERBOST, P. M., J. VAN ROOIJ, G. FLIK, R. A. C. LOCK, and S. E. WENDELAAR BONGA. "The Movement of Cadmium Through Freshwater Trout Branchial Epithelium and its Interference with Calcium Transport." Journal of Experimental Biology 145, no. 1 (1989): 185–97. http://dx.doi.org/10.1242/jeb.145.1.185.

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Exposure of freshwater trout (Salmo gairdneri) to waterborne Cd2+ results in accumulation of the metal in the branchial epithelial cells and its appearance in the blood. Cd2+ apparently enters the cells via Ca2+ channels in the apical membrane. Transfer of Cd2+ through the basolateral membrane is probably by diffusion. Inhibition by Cd2+ of transepithelial Ca2+ influx is time- and Cd2+-concentration-dependent. The inhibition of transepithelial Ca2+ influx is accompanied by blockage of apical Ca2+ channels. In line with the assumption that cytosolic Cd2+ inhibits Ca2+ uptake by inhibiting the b
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32

Kim, Gyeong Sung, and Yunho Hwang. "Wave-Powered and Zero-Discharging Membrane-Distillation Desalination System: Conceptual Design and Analysis." Water 14, no. 12 (2022): 1897. http://dx.doi.org/10.3390/w14121897.

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There are many islands without full access to electricity around the world. These energy-poor regions generally have drinking water supply issues too. Renewable energy-powered desalination units can convert seawater to freshwater by using such as oceanic wave energy to mitigate the water limitation in small islands. A novel wave-powered floating desalination system (WavoWater) was proposed for easy on-site deployment and minimal environmental impact. WavoWater can produce freshwater using a vacuum-applied air-gap membrane distillation (AGMD) system, and the heat needed for the AGMD is provided
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33

Simmons, Jeremy W., and James D. Van de Ven. "A Comparison of Power Take-Off Architectures for Wave-Powered Reverse Osmosis Desalination of Seawater with Co-Production of Electricity." Energies 16, no. 21 (2023): 7381. http://dx.doi.org/10.3390/en16217381.

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Several power take-off (PTO) architectures for wave-powered reverse osmosis (RO) desalination of seawater are introduced and compared based on the annual average freshwater production and the size of the components, which strongly relate to the costs of the system. The set of architectures compared includes a novel series-type PTO architecture not previously considered. These seawater hydraulic PTO architectures are composed of a WEC-driven pump, an RO module, an intake charge pump driven by an electric motor, and a hydraulic motor driving an electric generator for electric power production. T
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34

Parekh, N. "A novel method for infusing drugs continuously into the renal artery of rats." American Journal of Physiology-Renal Physiology 268, no. 5 (1995): F967—F971. http://dx.doi.org/10.1152/ajprenal.1995.268.5.f967.

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A method is described to achieve a homogeneous intravascular distribution of drugs infused into the renal artery of anesthetized rats. The device for intrarenal infusion consisted of a multiple-catheter system with a cannula inserted into the renal artery, which was connected to different lines for drug infusions and to one line for oscillating blood back and forth in the renal cannula with a magnetic membrane pump. The blood oscillation served to mix the drugs with renal arterial blood. To verify the usefulness of this procedure, Lissamine green was infused into the renal artery; without the
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35

Sabolic, I., W. Haase, and G. Burckhardt. "ATP-dependent H+ pump in membrane vesicles from rat kidney cortex." American Journal of Physiology-Renal Physiology 248, no. 6 (1985): F835—F844. http://dx.doi.org/10.1152/ajprenal.1985.248.6.f835.

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The presence of membrane vesicles containing an ATP-driven H+ pump was demonstrated in rat kidney cortex homogenate using the delta pH-sensitive dye acridine orange (AO). These vesicles were purified by differential and Percoll density gradient centrifugation. ATP-driven H+ uptake was about 20-fold enriched compared with the homogenate. Determination of marker enzyme activities indicated that these vesicles do not originate from brush border and basolateral membranes, lysosomes, endoplasmic reticulum, mitochondria, Golgi membranes, or red blood cells. The identity with brush border membranes w
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36

Daykin, Jake, Jonathan R. C. Woods, Roman Bek, et al. "Bi-frequency operation in a membrane external-cavity surface-emitting laser." PLOS ONE 18, no. 7 (2023): e0289223. http://dx.doi.org/10.1371/journal.pone.0289223.

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We report on the achievement of continuous wave bi-frequency operation in a membrane external-cavity surface-emitting laser (MECSEL), which is optically pumped with up to 4 W of 808 nm pump light. The presence of spatially specific loss of the intra-cavity high reflectivity mirror allows loss to be controlled on certain transverse cavity modes. The regions of spatially specific loss are defined through the removal of Bragg layers from the surface of the cavity high reflectivity mirror in the form of crosshair patterns with undamaged central regions, which are created using a laser ablation sys
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37

Jin, Zonchao, and Jianan Qin. "An Electric Model with Time Varying Resistance for a Pneumatic Membrane Blood Pump." ASAIO Journal 39, no. 1 (1993): 56–61. http://dx.doi.org/10.1097/00002480-199301000-00013.

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38

Jin, Zonghao, and Jianan Qin. "An Electric Model with Time Varying Resistance for a Pneumatic Membrane Blood Pump." ASAIO Journal 39, no. 1 (1993): 56–61. http://dx.doi.org/10.1097/00002480-199339010-00013.

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39

Lew, Virgilio L., Nuala Daw, Deisy Perdomo, Zipora Etzion, Robert M. Bookchin, and Teresa Tiffert. "Distribution of plasma membrane Ca2+ pump activity in normal human red blood cells." Blood 102, no. 12 (2003): 4206–13. http://dx.doi.org/10.1182/blood-2003-06-1787.

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Abstract The plasma membrane calcium pump (PMCA) is the only active Ca2+ transporter in human red blood cells (RBCs). Previous measurements of maximal Ca2+ extrusion rates (Vmax) reported only mean values in the RBC population. Despite early evidence for differences in Ca2+ extrusion capacity among RBCs, the precise Vmax distribution remained unknown. It was important to characterize this distribution to assess the range and modality (uni- or multimodal) of PMCA Vmax variation and the likelihood of RBCs with elevated [Ca2+]i in the circulation participating in physiologic and pathologic proces
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40

Su, Chih Wei, and Chao Heng Chien. "Design and Fabrication of Blood Drawing Device." Advanced Materials Research 291-294 (July 2011): 1233–36. http://dx.doi.org/10.4028/www.scientific.net/amr.291-294.1233.

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This paper proposed a novel device to draw blood from the finger. PDMS is used as an actuated pump, the device has an advantage in a precise controlled the volume of blood drawn. The operation process of the blood drawing device with the deflection of the PDMS membrane is to generate negative pressure. For measuring the performance of the device, we also fabricate a PDMS tank as pig’s skin. Two different viscosity fluid are used, the red ink and pig’s blood. The result of red ink drawn is 0.2cc, and the pig’s blood is 0.1cc.
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41

Benaim, G., S. N. J. Moreno, G. Hutchinson, et al. "Characterization of the plasma-membrane calcium pump from Trypanosoma cruzi." Biochemical Journal 306, no. 1 (1995): 299–303. http://dx.doi.org/10.1042/bj3060299.

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Despite previous reports [McLaughlin (1985) Mol. Biochem. Parasitol. 15, 189-201; Ghosh, Ray, Sarkar and Bhaduri (1990) J. Biol. Chem. 265, 11345-11351; Mazumder, Mukherjee, Ghosh, Ray and Bhaduri (1992) J. Biol. Chem. 267, 18440-18446] suggesting that the plasma-membrane Ca(2+)-ATPases of different trypanosomatids differ from the Ca2+ pumps present in mammalian cells, Trypanosoma cruzi plasma-membrane Ca(2+)-ATPase shares several characteristics with the Ca2+ pumps present in other systems. This enzyme could be partially purified from epimastigote plasma-membrane vesicles using calmodulin-aga
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42

Dixon, Rose Ellen, Fiona C. Britton, Salah A. Baker, et al. "Electrical slow waves in the mouse oviduct are dependent on extracellular and intracellular calcium sources." American Journal of Physiology-Cell Physiology 301, no. 6 (2011): C1458—C1469. http://dx.doi.org/10.1152/ajpcell.00293.2011.

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Spontaneous contractions of the myosalpinx are critical for oocyte transport along the oviduct. Slow waves, the electrical events that underlie myosalpinx contractions, are generated by a specialized network of pacemaker cells called oviduct interstitial cells of Cajal (ICC-OVI). The ionic basis of oviduct pacemaker activity is unknown. Intracellular recordings and Ca2+ imaging were performed to examine the role of extracellular and intracellular Ca2+ sources in slow wave generation. RT-PCR was performed to determine the transcriptional expression of Ca2+ channels. Molecular studies revealed m
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43

Zainab, Zainab, Sadiq J. .., and Wisam S. Alobaidi. "Intelligent System for the Classification of Arterial Blood Pressure Waveform Abnormalities Due to Mistiming in Intra-Aortic Balloon Pump." Journal of Intelligent Systems and Internet of Things 13, no. 1 (2024): 59–70. http://dx.doi.org/10.54216/jisiot.130105.

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Cardiovascular diseases detection or diagnosis on appropriate time is crucial to avoid health complications. In this study, an advanced procedure for classifying changes in the blood pressure has been used analyzing the wave-forms inside the arterial system where such variation can occur due to improper timing in intra-aortic balloon pump (IABP) control. Inaccurate pressure extends with probable injury can be caused by improper timing in the heart valve in both pumping and compression of the balloon. This investigation focuses on accurately recognizing and classifying any irregularities in the
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44

Datt, Bharat, Moui B. Nguyen, Gary Plancher, et al. "The Impact of Roller Pump vs. Centrifugal Pump on Homologous Blood Transfusion in Pediatric Cardiac Surgery." Journal of ExtraCorporeal Technology 49, no. 1 (2017): 36–43. http://dx.doi.org/10.1051/ject/201749036.

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Centrifugal pumps are considered to be less destructive to blood elements(1) when compared to roller pumps. However, their large prime volumes render them unsuitable as arterial pumps in heart lung machine (HLM) circuitry for children. In November of 2014, the circuit at Arnold Palmer Hospital, a Biomedicus BP-50 with kinetic assist venous drainage (KAVD) and 1/4″ tubing was converted to a roller pump in the arterial position with gravity drainage. Vacuum-assisted venous drainage (VAVD) was mounted on the HLM as a backup, but not used. Tubing was changed to 3/16″ in the arterial line in patien
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45

Thiara, AS. "Influence of Extracorporeal Membrane Oxygenation Circuit on Nutritional Supplements." Journal of Clinical Research and Reports 3, no. 5 (2020): 01–09. http://dx.doi.org/10.31579/2690-1919/057.

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Background The main function of extracorporeal membrane oxygenation (ECMO) is to provide systemic perfusion and gas exchange for patients with severe, acute respiratory or cardiac illness. The ECMO system consists of blood pump and a membrane oxygenator. ECMO oxygenator fibers, blood pump and tubing may bind circulating compounds such as drugs and nutritional components during ECMO support. Any loss of vital nutrients due to adsorption to the ECMO circuits may lead to further nutritional debilitation in critical ill patients. Objective The purpose of study is to analyze the amount of nutrition
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46

Gilotra, Nisha A., and Gerin R. Stevens. "Temporary Mechanical Circulatory Support: A Review of the Options, Indications, and Outcomes." Clinical Medicine Insights: Cardiology 8s1 (January 2014): CMC.S15718. http://dx.doi.org/10.4137/cmc.s15718.

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Cardiogenic shock remains a challenging disease entity and is associated with significant morbidity and mortality. Temporary mechanical circulatory support (MCS) can be implemented in an acute setting to stabilize acutely ill patients with cardiomyopathy in a variety of clinical situations. Currently, several options exist for temporary MCS. We review the indications, contraindications, clinical applications, and evidences for a variety of temporary circulatory support options, including the intra-aortic balloon pump (IABP), extracorporeal membrane oxygenation (ECMO), CentriMag blood pump, and
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47

Fathallah, H., E. Coezy, RS de Neef, MD Hardy-Dessources, and F. Giraud. "Inhibition of deoxygenation-induced membrane protein dephosphorylation and cell dehydration by phorbol esters and okadaic acid in sickle cells." Blood 86, no. 5 (1995): 1999–2007. http://dx.doi.org/10.1182/blood.v86.5.1999.bloodjournal8651999.

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Deoxygenation (DO) of sickle cell anemia red blood cells (SS cells) induces membrane permeabilization to Ca2+, Na+, and K+ and cell dehydration mostly through the activation of the Ca(2+)-dependent K+ channels. We show that DO of both SS cells and normal red blood cells was accompanied by a nonspecific dephosphorylation of membrane proteins. After treatment with a protein kinase C activator (phorbol myristate acetate) or a phosphoprotein phosphatase inhibitor (okadaic acid), the level of membrane protein phosphorylation in deoxygenated cells was maintained higher or equal, respectively, to tha
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48

Massey, Katherine J., Quanwen Li, Noreen F. Rossi, Susan M. Keezer, Raymond R. Mattingly, and Douglas R. Yingst. "Phosphorylation of rat kidney Na-K pump at Ser938 is required for rapid angiotensin II-dependent stimulation of activity and trafficking in proximal tubule cells." American Journal of Physiology-Cell Physiology 310, no. 3 (2016): C227—C232. http://dx.doi.org/10.1152/ajpcell.00113.2015.

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How angiotensin (ANG) II acutely stimulates the Na-K pump in proximal tubules is only partially understood, limiting insight into how ANG II increases blood pressure. First, we tested whether ANG II increases the number of pumps in plasma membranes of native rat proximal tubules under conditions of rapid activation. We found that exposure to 100 pM ANG II for 2 min, which was previously shown to increase affinity of the Na-K pump for Na and stimulate activity threefold, increased the amount of the Na-K pump in plasma membranes of native tubules by 33%. Second, we tested whether previously obse
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49

Chávez, Gino, Luis Cortés-Vega, and Adrián Sotomayor. "Semigroup theory and finite element method applied to a non-linear dissipative wave equation." Journal of Physics: Conference Series 2701, no. 1 (2024): 012105. http://dx.doi.org/10.1088/1742-6596/2701/1/012105.

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Abstract We study the wave equation with a non-linear dissipative term associated to a bidimensional membrane with fixed boundary. We use the semigroup theory to consider the existence and uniqueness of solutions to the problem and we implement the finite element method to analyse the vibrating evolutionary equation. In particular we use Comsol Multiphysics software with a rectangular mesh to analyze the corresponding evolutionary system. We mention that this system can appear, for example, in the diaphragm of a centrifugal pump in mining processes.
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50

Kopp, Ruedger, Ralf Bensberg, Jutta Arens, et al. "A Miniaturized Extracorporeal Membrane Oxygenator with Integrated Rotary Blood Pump: Preclinical In Vivo Testing." ASAIO Journal 57, no. 3 (2011): 158–63. http://dx.doi.org/10.1097/mat.0b013e31820bffa9.

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