Academic literature on the topic 'Wen jian'

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Journal articles on the topic "Wen jian"

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Chao, Xue-lin, Shu-zhen Jiang, Jian-wen Xiong, Jin-qiong Zhan, Bo Wei, Chun-nuan Chen, and Yuan-jian Yang. "Erratum to: Changes of Serum Insulin-like Growth Factor-2 Response to Negative Symptom Improvements in Schizophrenia Patients Treated with Atypical Antipsychotics." Current Medical Science 40, no. 5 (October 2020): 997. http://dx.doi.org/10.1007/s11596-020-2256-3.

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The article “Changes of Serum Insulin-like Growth Factor-2 Response to Negative Symptom Improvements in Schizophrenia Patients Treated with Atypical Antipsychotics”, written by Xue-lin CHAO, Shu-zhen JIANG, Jian-wen XIONG, Jin-qiong ZHAN, Bo WEI, Chun-nuan CHEN, Yuan-jian YANG was originally published electronically on the publisher’s internet portal on June 2020 without open access. With the author(s)’ decision to opt for Open Choice, the copyright of the article is changed to © The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
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Төрбат, Цагаан. "Ашина овгийн хатны эртний геном нь Хөх түрэгийн хаант улсыг Зүүн хойд Азийн гаралтай болохыг харуулжээ." Mongolian Journal of Anthropology, Archaeology and Ethnology 13, no. 1 (May 10, 2024): 141–45. http://dx.doi.org/10.22353/mjaae.20241301013.

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Xiao‐Min Yang, Hai‐Liang Meng, Jian‐Lin Zhang, Yao Yu, Edward Allen, Zi‐Yang Xia, Kong‐Yang Zhu, Pan‐Xin Du, Xiao‐Ying Ren, Jian‐Xue Xiong, Xiao‐Yu Lu, Yi Ding, Sheng Han, Wei‐Peng Liu, Li Jin, Chuan‐Chao Wang, and Shao‐Qing Wen. Ancient genome of Empress Ashina reveals the Northeast Asian origin of Göktürk Khanate. – Journal of Systematic and Evolution. Institute of Botany, Chinese Academy of Sciences. 2023. Volume 00 (0) 1-9.
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Diyaljee, Vishnu. "Discussion of “New Model for Predicting Permanent Strain of Granular Materials in Embankment Subjected to Low Cyclic Loadings” by Wen-Bo Chen, Wei-Qiang Feng, Jian-Hua Yin, Jin-Miao Chen, Lalit Borana, and Ren-Peng Chen." Journal of Geotechnical and Geoenvironmental Engineering 147, no. 11 (November 2021): 07021026. http://dx.doi.org/10.1061/(asce)gt.1943-5606.0002656.

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Chen, Wen-Bo, Wei-Qiang Feng, Jian-Hua Yin, Jin-Miao Chen, Lalit Borana, and Ren-Peng Chen. "Closure to “New Model for Predicting Permanent Strain of Granular Materials in Embankment Subjected to Low Cyclic Loadings” by Wen-Bo Chen, Wei-Qiang Feng, Jian-Hua Yin, Jin-Miao Chen, Lalit Borana, and Ren-Peng Chen." Journal of Geotechnical and Geoenvironmental Engineering 147, no. 11 (November 2021): 07021027. http://dx.doi.org/10.1061/(asce)gt.1943-5606.0002657.

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Huang, Yu-zhou, Ming-Yi Sang, Pei-Wen Xi, Ruo-Xi Xu, Meng-Yuan Cai, Zi-Wen Wang, Jian-Yi Zhao, Yi-Han Li, Ji-Fu Wei, and Qiang Ding. "Abstract 7220: Emerging combination strategy: FANCI suppression induces PARP1 redistribution to enhance efficacy of PARP inhibitors in breast cancer." Cancer Research 84, no. 6_Supplement (March 22, 2024): 7220. http://dx.doi.org/10.1158/1538-7445.am2024-7220.

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Abstract While polyADP-ribose polymerase (PARP) inhibitors have made advancements in the treatment of breast cancer, challenges such as chemotherapy resistance and limited application persist. Fanconi AnemiaComplementation Group I (FANCI), a DNA repair protein associated with breast cancer development, represents a potential target for novel combination therapeutic strategies. However, the role of FANCI in breast cancer and its impact on the efficacy of PARP inhibitors require further investigation. In our study, we analyzed FANCI expression in breast cancer tissues and cell lines, and its correlation with clinical parameters and patient prognosis. Lentiviral vectors were utilized and functional assays were performed to evaluate the effects of FANCI modulation on breast cancer cell growth and migration. Co-immunoprecipitation assays and protein interaction analysis were conducted to identify the interaction between FANCI and PARP1 and determine the specific binding region. The functionality and nuclear distribution of PARP1 were assessed upon FANCI modulation. Finally, the sensitivity of breast cancer cells to the PARP inhibitor talazoparib upon FANCI knockdown was evaluated in vitro and in vivo. Our findings demonstrated that FANCI was overexpressed in breast cancer and associated with poor prognosis. FANCI significantly promoted breast cancer cell proliferation both in vitro and in vivo. We identified the interaction between FANCI and PARP1, specifically at the FANCI helical domain 2 binding site. FANCI knockdown led to reduced nuclear localization of PARP1 and decreased PARP1 activity. Importantly, combination treatment with FANCI knockdown and talazoparib significantly inhibited cancer growth in vitro and in vivo. Additionally, we found that the cyclin-dependent kinase (CDK) 4/6 inhibitor palbociclib, which effectively suppresses FANCI protein expression, exhibited a robust synergistic effect with talazoparib both in vitro and in vivo. In conclusion, FANCI is a novel therapeutic target for breast cancer. Suppression of FANCI regulates PARP1 redistribution and activity, making breast cancer cells more responsive to PARP inhibitors. This combination therapeutic strategy shows potential in enhancing the effectiveness of PARP inhibitors for breast cancer treatment, regardless of BRCA mutations. Citation Format: Yu-zhou Huang, Ming-Yi Sang, Pei-Wen Xi, Ruo-Xi Xu, Meng-Yuan Cai, Zi-Wen Wang, Jian-Yi Zhao, Yi-Han Li, Ji-Fu Wei, Qiang Ding. Emerging combination strategy: FANCI suppression induces PARP1 redistribution to enhance efficacy of PARP inhibitors in breast cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 7220.
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Shi, Guoming, Xiaoyong Huang, Tianfu Wen, Tianqiang Song, Ming Kuang, Haibo Mou, Lequn Bao, et al. "Abstract CT153: Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study." Cancer Research 83, no. 8_Supplement (April 14, 2023): CT153. http://dx.doi.org/10.1158/1538-7445.am2023-ct153.

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Abstract Background: Pemigatinib is a selective FGFR inhibitor that showed effectiveness and tolerability in patients with cholangiocarcinoma (CAA) with FGFR2 fusion or rearrangement. Data from prior data cutoffs (primary: Jan 29th, 2021; initial update: Dec 20th, 2021) showed that patients receiving pemigatinib had durable responses. Confirmed objective response rate (ORR) (60%) met the primary endpoint, median duration of response (DOR) was 8.3 months, median progression-free survival (PFS) was 9.1 months at the initial update (G-M. Shi et al. ASCO 2022). Safety results were also consistent with previously reported data on pemigatinib. Here we report updated overall survival (OS) results. Methods: Patients aged 18 years or older with recurrent or metastatic CCA that failed at least one prior systemic therapy were enrolled. Thirty-one subjects with documented FGFR2 fusion or rearrangement received 13.5 mg pemigatinib. The primary efficacy endpoint was ORR assessed by the independent radiological review committee (IRRC) per RECIST V1.1. And the second endpoints included disease control rate (DCR), DOR, PFS, and OS. Updated OS were evaluated by Cox proportional hazards model and summarized using Kaplan-Meier methods. Results: At data cutoff (December 28th, 2022), a total of 30 patients were assessed (1 participant excluded due to inadequate FGFR2 aberrant frequency). Median age was 56 years (range, 28-68).With a median OS follow-up of 25.6 months (95% CI, 23.0-25.8), the median OS was 23.9 months (95% CI, 15.2-NC), with 16 (53.3%) OS events. Estimated OS rate at 12 month, 18 month and 24 month were 73.3% (95% CI, 53.7%-85.7%), 66.5% (95% CI, 46.7%-80.4%), and 41.4% (95% CI, 22.4%-59.4%), respectively. No new safety signals were observed. Conclusions: These updated results demonstrated encouraging and durable survival benefit of pemigatinib in Chinese patients with recurrent or metastatic cholangiocarcinoma with FGFR2 fusion or rearrangement. Clinical trial identification: NCT04256980. Editorial acknowledgment: Guoming Shi and Xiaoyong Huang contributed equally to this work. Jian Zhou is the corresponding author. Citation Format: Guoming Shi, Xiaoyong Huang, Tianfu Wen, Tianqiang Song, Ming Kuang, Haibo Mou, Lequn Bao, Haitao Zhao, Hong Zhao, Xielin Feng, Bixiang Zhang, Tao Peng, Yubao Zhang, Xiangcheng Li, Hongsheng Yu, Yu Cao, Yang Luo, Ye Chen, Mingxia Chen, Jia Fan, Jian Zhou. Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr CT153.
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Lin, Ziyou, Jingwei Li, Jian Zhang, Weineng Feng, Jiaye Lu, Xiaofan Ma, Wen Ding, et al. "Abstract 415: Metabolic reprogramming driven by IGF2BP3-COX6B2 axis promotes acquired resistance to EGFR-TKIs in non-small lung cancer." Cancer Research 83, no. 7_Supplement (April 4, 2023): 415. http://dx.doi.org/10.1158/1538-7445.am2023-415.

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Abstract Acquired resistance represents a bottleneck to molecular targeted therapy in lung cancer. Metabolic adaptation is a distinct hallmark of human lung cancer, but its role in acquired resistance has not been fully understood. In this study, we discovered a novel mechanism of TKI resistance involved in IGF2BP3-dependent crosstalk between the epigenetic modifications and metabolic reprogramming through the IGF2BP3-COX6B2 axis. We demonstrated the upregulated expression of RNA binding protein IGF2BP3 reduced the sensitivity of TKI treatment and exacerbated the development of drug resistance via promoting oxidative phosphorylation (OXPHOS). Analysis of patient samples revealed a positive correlation between IGF2BP3 and COX6B2 and poor prognosis in lung cancer patients. We further confirmed that COX6B2 is a key downstream target in IGF2BP3-mediated acquired TKI-resistance. Mechanistically, IGF2BP3 bound to the 3’-untranslated region of COX6B2 in an m6A-dependent manner to increase COX6B2 mRNA stability. Moreover, IGF2BP3 significantly enhanced OXPHOS capacity in lung cancer through the IGF2BP3-COX6B2 axis by regulating nicotinamide metabolism, thus resulting in TKI resistance in lung cancer. Inhibition of OXPHOS with IACS-010759, a small-molecule inhibitor, resulted in remarkable growth inhibition in vitro and in vivo in a gefitinib-resistant patient-derived xenograft model. Collectively, our findings suggest that metabolic reprogramming directed by the IGF2BP3-COX6B2 axis plays a critical role in TKI resistance, and targeting the metabolic pathway provides a new therapeutic strategy to overcome EGFR-TKI resistance in lung cancer. Citation Format: Ziyou Lin, Jingwei Li, Jian Zhang, Weineng Feng, Jiaye Lu, Xiaofan Ma, Wen Ding, Shumin Ouyang, Jinjian Lu, Peibin Yue, Guohui Wan, Peiqing Liu, Xiaolei Zhang. Metabolic reprogramming driven by IGF2BP3-COX6B2 axis promotes acquired resistance to EGFR-TKIs in non-small lung cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 415.
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Xue, Wei-Wei, Huan-Nan Wang, Zhi-Meng Wang, Meng-Xi Qiu, Jing Che, Feng-Jiao Deng, and Jiang-Dong Liu. "Cloning and Characterization of ifitm1 and ifitm3 Expression During Early Zebrafish Development - CORRIGENDUM." Zygote 24, no. 1 (July 21, 2015): 159. http://dx.doi.org/10.1017/s0967199415000398.

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The authors apologise for errors in the corresponding authors details given on page 1 of the article. Below is the correct information of the corresponding author and email address :1) Wei-Wei Xue, Huan-Nan Wang, Zhi-Meng Wang, Meng-Xi Qiu, Jing Che, Feng-Jiao Deng* and Jiang-Dong Liu*2) *All correspondence to: Feng-Jiao Deng and Jiang-Dong Liu. e-mail: fish4@whu.edu.cn3) All authors are from the same one laboratory. The second laboratory was superfluous and should be deleted.
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Hsu, Yuan Hung, Chih-Lung Chen, Jhih-Yun Jian, Ming-Cheng Wei, Wen-Yuan Hsieh, Chia-Wen Huang, Yung-Chu Chen, Tzu-Hsin Liao, and Shian-Jy Wang. "Abstract 818: Preclinical studies of the cabazitaxel nanoformulation MPB-1734 support therapeutic application in chemo-resistant solid tumors and synergistic benefit in combination with immune checkpoint inhibitor." Cancer Research 83, no. 7_Supplement (April 4, 2023): 818. http://dx.doi.org/10.1158/1538-7445.am2023-818.

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Abstract Background: Cabazitaxel (CBZ) is a second-generation taxane that has the potential to overcome taxane-resistance due to the low affinity for the P-glycoprotein efflux pump. However, with the high systemic toxicity such as neutropenia and hypersensitivity, the clinical use is restricted to patients with metastatic castration-resistant prostate cancer who show progression after docetaxel-based chemotherapy. MPB-1734 is a CBZ nanoformulation which is currently being evaluated as monotherapy in patients with advanced solid tumors in a Phase 1/2a trial (NCT04643418). It is developed to overcome the limitations associated with CBZ application and as potential therapeutic agent for chemo-resistant cancers. This work outlines the results of preclinical studies that support the tumor targeting ability, improved safety profiles, significant therapeutic effect, and synergistic benefit in combination with immune checkpoint inhibitor. Methodology: A series of nonclinical studies of MPB-1734 were conducted including toxicology evaluations in two species and the antitumor activity evaluations in a range of xenograft mice models as cervical cancer (KB), ovarian cancer (OVCAR3) and platinum-resistant human ovarian cancer patient-derived-xenograft (PDX) model (OV0276). The antitumor activity of MPB1734 combined with anti-PD-1 antibody were also evaluated in the syngenetic 4T1 breast cancer mice model. Results: Toxicology evaluations of MPB-1734 demonstrated the safety profiles of CBZ were significantly improved, and the tolerated doses of MPB-1734 are at least 2 folds higher than commercial formulation. An in-vivo tumor targeting study showed that MPB1734 mainly accumulated in the tumor sites, rather than in the vital organs. MPB1734 exhibited a better efficacy compared to commercial formulation in KB and OVCAR3 models. For platinum-resistant PDX model, MPB-1734 demonstrated significant anti-tumor efficacy (TGI:100%, p<0.001). For 4T1 mice model, MPB-1734 combined with anti-PD-1 antibody demonstrated synergistic benefit (TGI: 78.6%) compared to anti-PD-1 antibody monotherapy (TGI: 2.8%) and MPB-1734 monotherapy (TGI: 52.9%). This synergistic benefit may result from increased CD8+ T cells in tumor region after MPB-1734 treatment. Conclusion: MPB-1734 can reduce the major dose-limiting side effect (neutropenia) of CBZ and increase the tolerated dose. With tumor targeting ability, superior antitumor effects were demonstrated as compared with commercial formulation in a range of cancer models. MPB-1734 combined with anti-PD-1 antibody showed synergistic benefit in tumor inhibition. These preclinical results support the potential use of MPB-1734 as therapeutic agent for chemo-resistant cancer with monotherapy or combination therapy with immuno-oncology agents. Citation Format: Yuan Hung Hsu, Chih-Lung Chen, Jhih-Yun Jian, Ming-Cheng Wei, Wen-Yuan Hsieh, Chia-Wen Huang, Yung-Chu Chen, Tzu-Hsin Liao, Shian-Jy Wang. Preclinical studies of the cabazitaxel nanoformulation MPB-1734 support therapeutic application in chemo-resistant solid tumors and synergistic benefit in combination with immune checkpoint inhibitor [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 818.
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Luo, J., Q. Y. Su, J. Q. Zhang, J. Qiao, S. X. Zhang, C. Wang, and X. F. LI. "POS1353 COMPOSITION AND ASSOCIATIONS OF THE GUT MICROBIOTA IN BECHET’S DISEASE WITH PERIPHERAL LYMPHOCYTE SUBSETS AND CYTOKINES." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1015.2–1015. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3430.

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BackgroundBechet’s disease (BD) is a chronic multisystemic vasculitis with genetic and abnormal immune response. Growing evidences suggests gut microbiota compositional alteration may have an association with immune dysfunction in patients with BD.ObjectivesThis study aims to investigate the gut microbiota between BD and healthy controls (HCs) and analyse relevancy between bacterial and peripheral lymphocyte subsets and cytokines.MethodsFecal samples obtained from 22 BD patients and 22 normal-age and gender-matched HCs in this study. The gut microbiota were assessed with 16s rRNA sequencing and the flow cytometry was used to dectect peripheral lymphocyte subsets. C-reaction protein (CRP), Erythrocyte sedimentation rate (ESR), complement C3 and C4 were also assigned for disease activity measure. The edgeR package was used for differential abundance analysis. Difference of alpha diversity indices, bacterial abundances, and the F/B ratio were carried out using the Wilcoxon rank-sum test (R v.4.0.1). The differential abundance of flora and CRP, ESR, C3 and C4 between BD patients and HCs was assessed by pearson’s correlation analysis.ResultsAs for alpha diversity, the Shannon (p < 0.05) and Simpsonance analysis. Difference of alpha diversity indices, bacterial abundances, and the F/B ratio were carried out using the Wilcoxon rank-sum test (R v.4.0.1). The differential abundamicrobial community structures between BD and HCs (R = 0.053, p = 0.051; Figure 1B). The gut microbiota compositions of BD differed form those of HCs (Figure 1C). Four species of flora distinctly difference were found in BD (p < 0.05; Figure 1D). There was significant positive correlations between Tregs and Verrucomicrobiota (p < 0.05), and Proteobacteria (p < 0.05), Th1 and Proteobacteria (p < 0.05), ESR and Verrucomicrobiota (p < 0.01), but negatives correlation between TNF-α and Desulfobactbiota (p < 0.05; Figure 1E).ConclusionPattients with CTD had disbiosis of gut microbiota charaterized by impared diversity and abnomal composition, which was closely correlated with peripheral lymphocyte subsets and disease activity measures.References[1]Margaret Alexander, Qi Yan Ang, Renuka R Nayak, et al. Human gut bacterial metabolism drives Th17 activation and colitis. Cell Host Microbe. 2022 Jan 12;30(1):17-30.e9. doi: 10.1016/j.chom.2021.11.001. Epub 2021 Nov 24.[2]Yi-Wen Tsai, Jia-Ling Dong, Yun-Jie Jian, et al. Gut Microbiota-Modulated Metabolomic Profiling Shapes the Etiology and Pathogenesis of Autoimmune Diseases. Microorganisms. 2021 Sep 10;9(9):1930. doi: 10.3390/microorganisms9091930.AcknowledgementsThis work was supported by the National Natural Science Foundation of China (No. 82001740).Disclosure of InterestsNone declared
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Dissertations / Theses on the topic "Wen jian"

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Wu, Tsz Wing. "Li Yu gai bian ju yan jiu : jian lun wen ren chuan qi yu shi min wen xue zhi rong he /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?HUMA%202006%20WU.

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Huang, Wen-Hung Kevin [Verfasser], Jian-Jia [Akademischer Betreuer] Chen, and Jan [Gutachter] Reineke. "Scheduling algorithms and timing analysis for hard real-time systems / Wen-Hung Kevin Huang ; Gutachter: Jan Reineke ; Betreuer: Jian-Jia Chen." Dortmund : Universitätsbibliothek Dortmund, 2017. http://d-nb.info/1135487804/34.

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Wen, Jian Verfasser], Carsten [Akademischer Betreuer] [Bolm, and Dieter [Akademischer Betreuer] Enders. "Copper-catalyzed dealkylations and rhodium-catalyzed C−H functionalizations of NH-sulfoximines / Jian Wen ; Carsten Bolm, Dieter Enders." Aachen : Universitätsbibliothek der RWTH Aachen, 2018. http://d-nb.info/1170780016/34.

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Wen, Jian [Verfasser], Carsten [Akademischer Betreuer] Bolm, and Dieter [Akademischer Betreuer] Enders. "Copper-catalyzed dealkylations and rhodium-catalyzed C−H functionalizations of NH-sulfoximines / Jian Wen ; Carsten Bolm, Dieter Enders." Aachen : Universitätsbibliothek der RWTH Aachen, 2018. http://d-nb.info/1170780016/34.

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Chan, Ngon Fung. "Yi gu si chao yu bai hua wen xue shi de jian gou : Hu Shi yu Gu Jiegang /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?HUMA%202004%20CHANN.

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Fu, Ho-yi Crystal, and 傅皓皚. "Government document systems in Qin dynasty evident in Qin bamboo slips = Cong Qin jian kan Qin dai gong wen zhi du." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/192996.

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It is a wonder to discover the remarkable progress the Qin Dynasty made two thousand years ago concerning its documentation systems. Ever since the excavation of the Shuihudi (in Chinese 睡虎地), we now know in Qin, there was the Rule Book of Implementation 《行書》律(about the laws on documentation systems). Unfortunately, there was no correspondence for cross examination. Not until the excavation of the Liye (里耶) site in 2002 were we able to identify the format of the correspondence between the central government, provinces and towns. From the 37000 bamboo slips of Qin which are rich in contents, we can see they covered every aspect. As well, the 2008 Yuelu (嶽麓)bamboo slips appeared to fill the gaps left by Shuihudi. They provide clues, allowing the author to reconstruct the profile of Qin’s documentation systems. Scholars working on the documentation systems of Qin through the bamboo slips appear to base their findings on only isolated excavations, such as the discussion of either Shuihudi or Liye. But when they researched on the postal system which was central to the wider documentation systems, they had to rely on the clues provided by the Warring States Period, or on the bamboo slips of the Han Dynasty. There are thus limitations. For example, we cannot assume that Han must have inherited its systems from Qin. This thesis looks at the many unearthed bamboo slips having to do with Qin’s documentation systems, revisits and organizes current researches and attempts to reconstruct the state of documentation in Qin. 有誰想過二千年前的秦朝,其公文制度已發展至一定程度?1975年睡虎地秦簡出土後,讓我們知道秦代已有《行書》律(與公文制度有關的法律)。可惜的是,睡虎地秦簡中並沒有往來文書。直至2002年里耶秦簡出土後,大量的簡牘出土,使我們有機會看到秦代中央政府、郡、縣三層行政機構的往來文書,也讓我們了解秦代的公文已具備一定格式。37000枚的里耶秦簡,內容相當豐富,涉及當時各個層面。而2008年入藏的嶽麓秦簡,更補充了睡虎地秦簡《行書》律的不足。雖然嶽麓秦簡《行書律》簡文並非完整版本,但卻提供線索,讓本文能從中整合出秦代文書制度的面貌。 過往有關秦代公文制度的研究,學者傾向將研究範圍限定於某一出土簡牘中,如集中討論睡虎地秦簡或里耶秦簡中所見的公文制度。而當研究與秦代公文制度息息相關的郵傳制度時,往往要依靠戰國留下來的線索來推測秦代郵傳的情況,又或借助漢代的簡牘來逆推秦代的面貌,這種研究方法無疑是有局限的。我們不能單憑‘漢承秦制’而認定秦代制度與漢代一樣。本文希望透過集中研究各種出土秦簡,從中找出與秦代公文制度有關的資料,並將諸家研究進行整理,重塑當時公文制度的概況。
published_or_final_version
Chinese Language and Literature
Master
Master of Arts
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Wong, Kam-lai. "A study of primary teachers' opinions of the teachers' handbooks for Chinese language textbooks Xiao xue jiao shi dui "Zhongguo yu wen ke jiao shi yong shu" de yi jian diao cha yan jiu /." Click to view the E-thesis via HKUTO, 1998. http://sunzi.lib.hku.hk/hkuto/record/B31960522.

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Lau, Wai-hung. "The establishment of an electronic portfolio for Chinese language favours the development of students' language ability Wei Zhongguo yu wen ke jian dian zi hua xue xi li cheng dang an you zhu xue sheng yu wen neng li fa zhan /." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B40039973.

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Chen, Wenlan. "Bu qi jian pi qu tan fa zhi liao yuan fa xing gao xue ya bing de wen xian yan jiu yu tan tao /." click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b19986786a.pdf.

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Lin, Weikai. "Ming dai de jiang hai lian fang Chang Jiang jiang hai jiao hui shui yu fang wei de jian gou yu bei yu /." Yilan Xian Luodong Zhen : Ming shi yan jiu xiao zu, 2006. http://catalog.hathitrust.org/api/volumes/oclc/124057091.html.

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Books on the topic "Wen jian"

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Chunting, Jin, ed. Jiao dian wen jian. Zhanghua Xian: Yi qun tu shu you xian gong si, 2006.

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Qiuxiang, Li, ed. Wen jiao jian zhu. Beijing Shi: Sheng huo, du shu, xin zhi san lian shu dian, 2007.

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Chen, Dengxie. Wen jian. [Beijing: Beijing zhong xian tuo fang ke ji fa zhan you xian gong si, 2012.

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mian, Zhang ji. Wen jian. Bei jing: Zhong yang guang bo dian shi ta xue chu ban she, 1993.

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Yang, Xiaming. Meiguo wai jiao wen jian. Nanjing: Jiangsu ren min chu ban she, 2010.

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Alfred, Bell Charles. Xizang wai jiao wen jian. [Beijing: Beijing zhong xian tuo fang ke ji fa zhan you xian gong si, 2012.

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Zheng, Changshi. Han Jiang wen jian lu. Guangzhou Shi: Ji nan da xue chu ban she, 2018.

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United States. Department of State. Meiguo wai jiao wen jian. Beijing: Zhongguo she hui ke xue chu ban she, 1998.

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Ha'erbin shi fan da xue. Zhong wen xi. Gu ji zheng li yan jiu shi., ed. Tao Yuanming shi wen jiao jian. Ha'erbin Shi: Heilongjiang ren min chu ban she, 1985.

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Tongcheng, Li, ed. Zhong wai jian jiao mi wen. Taiyuan Shi: Shanxi ren min chu ban she, 2003.

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Book chapters on the topic "Wen jian"

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Zhang, Yao. "A Research on the Manchu-Chinese Bilingual Comparative Characteristics of the Yu Zhi Zeng Ding Qing Wen Jian Dictionary." In Lecture Notes in Computer Science, 480–94. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-0583-2_37.

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Lo, Yuet Keung. "The Zhuangzi and Wei-Jin Xuanxue." In Dao Companion to the Philosophy of the Zhuangzi, 447–66. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92331-0_18.

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Liu, Kai. "Wei-Jin-Northern and Southern Dynasties Civilization." In The History of Chinese Civilization, 87–101. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-7125-1_5.

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Danjun, Cai. "Literature in the Wei and Jin Dynasties." In Concise Reader of Chinese Literature History, 131–46. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-5814-6_11.

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ZHU, Yi-ting. "Ethical Thought in the Wei & Jin Period." In A Panoramic History of Traditional Chinese Ethics, 211–30. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-1252-7_4.

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Fang, Lili. "Ceramics of Wei, Jin and Southern and Northern Dynasties." In China Academic Library, 179–225. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9094-6_6.

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Cai, Shenshen. "Jiang Wen and His Signature Films: Let the Bullets Fly and Gone with the Bullets." In Contemporary Chinese Films and Celebrity Directors, 113–35. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-2966-0_6.

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Choi, Henry Sze Hang. "Reconceptualization of Historical Reality: The Dōjin Game San Guo Zhi Jiang Wei Zhuan." In Reconceptualizing the Digital Humanities in Asia, 175–88. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4642-6_11.

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Yang, Chun, Jiaqin Wei, and Ming Zhang. "Jiang X, Chen X, et al. v. Lin X, Weng X(A), et al." In Library of Selected Cases from the Chinese Court, 127–35. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6364-5_14.

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Xu, Hong. "The Time After the Wei and Jin Dynasties—City Wall and Grid Pattern." In Dynamic Interpretation of Early Cities in Ancient China, 19–30. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2387-5_2.

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Conference papers on the topic "Wen jian"

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Li, Yiguo, Dan Peng, Yongbao Zhang, Jin Lu, Xiaobo Wu, Jinhua Zhang, and Shuyun Zou. "JiNan MNSR Decommissioning." In 2013 21st International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icone21-15941.

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JiNan MNSR (Miniature Neutron Source Reactor) with thermal power 30kW is an undermoderated reactor of pool-tank type, and UAL4 alloy with 235U enrichment of 90% as fuel, light water as coolant and moderator, and metallic beryllium as reflector. The fission heat produced by the reactor is removed by the natural convection. JiNan MNSR went critical in May 1989, and shutdown in March 2008. The reactor operated 19 years safely with the accumulated power of 8.82×104 kWh. The main use was NAA (Neutron Activation Analysis) work. The spent fuel was removed from the JiNan MNSR site in Nov. 2009 already. The Jinan MNSR decommissioning documents were approved by Chinese competent authorities in Dec. 2010. The work on site was started in Jan. 2011, and completed in March 2011, the wastes were removed from the Jinan MNSR site. The decommissioning scope of JiNan MNSR includes decommissioning of its related systems, equipment and structures. The weight of intermediate level radioactive is 204.1kg, and the weight of low level radioactive waste is 2297 kg. They were all transported to West-north Waste disposal plant. The final measuring results are that α and β surface contamination in the reactor building are less than 0.06Bq/cm2 and 0.5Bq/cm2 respectively; the specified activities of the nuclides of 137Cs, 60Co and 90Sr in the soil are less than 1.4 Bq/kg,1.7 Bq/kg and 8.14 Bq/kg respectively; the specified activities of the nuclides of 137Cs, 60Co and 65Zn in the solid sample in the reactor building are less than 5.7 Bq/kg,7.8 Bq/kg and 1.7 Bq/kg respectively. The specified values for α and β surface contaminations in the reactor building are 0.08Bq/cm2 and 0.8Bq/cm2 respectively; they are 12 Bq/kg, 3 Bq/kg and 10 Bq/kg respectively for the limited values of the specified activities of the nuclides of 137Cs,60Co and 90Sr in the soil; the limited values of specified activities of the nuclides of 137Cs,60Co and 65Zn are 100Bq/kg respectively in the solid samples in the reactor building. The measuring results show that JiNan MNSR site meets the requirements of the unrestricted use.
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Peng, Xirui. "A Brief Analysis of Honeysuckle Patterns in Wei, Jin, Southern and Northern Dynasties." In 2nd International Conference on Language, Art and Cultural Exchange (ICLACE 2021). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210609.056.

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Li, Ying. "Study on driving the development of large data innovation and Zhuhai Jin Wan." In 2016 2nd International Conference on Education, Social Science, Management and Sports (ICESSMS 2016). Paris, France: Atlantis Press, 2017. http://dx.doi.org/10.2991/icessms-16.2017.92.

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Liu, Lin, Longfei Xiao, Zhiqiang Hu, and Lijun Yang. "Experimental Study on Wet Tow and Upending of a Truss Spar." In ASME 2011 30th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2011. http://dx.doi.org/10.1115/omae2011-49310.

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In recent years, with the development of the deepwater oil and gas exploitation, the Spar platform has received more and more attention. A lot of research work has been done on the Spar platform, but experimental study on the process of wet tow and upending of Truss Spar is seldom conducted. Recently, a wet tow and upending model test of a Truss Spar was carried out in the State Key Laboratory of Ocean Engineering in Shanghai Jiao Tong University. The hydrodynamic characteristics and the global loads on the key points of the Truss Spar during the period of wet tow and upending are focused on. In the wet tow tests, the tow resistance, 6DOF motions, global loads and the relative wave elevations are measured and analyzed. During the upending simulation, the measuring parameters consist of the motions and the global moment at the connection points between the hard tank and the truss. The test program and test results are presented and discussed in this paper offering the value references for the wet tow and upending operation in reality of the Truss Spar.
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Meng, C., A. Fournier, and W. Jin. "A Split-Node Method for Modeling Pulse and Hydraulic Fracturing." In 57th U.S. Rock Mechanics/Geomechanics Symposium. ARMA, 2023. http://dx.doi.org/10.56952/arma-2023-0493.

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ABSTRACT Reservoir stimulation is akey technology to enabling carbon and renewable resources recovery from the subsurface. The combination of pulse- and fluid-driven fracture propagation has great potential to revolutionize the hydro-fracturing industry. In this study, we present a novel method that extends the existing traction-at-split-node method to allow mode-I fracture propagation in both dynamic and quasi-static time frames. We implement this method in an open-source code, Defmod, that adaptively alternates between quasi-static and dynamic governing equations. We introduce a quasi-linear weakening failure criterion that allows irreversible tensile failures. To couple the fracture development and fluid flow inside and outside the fracture, we introduce a method to modify the fracture's neighboring elements by an anisotropic permeability as a function of fracture width. To ensure mass conservation, we balance the fluid-injection volume with the fracture-opening volume, by defining virtual fluid sources in the neighboring elements. We first compare an example of two-dimensional (2D) pulse-driven fracturing with experimental results. Then we compare an example of 3D penny-shaped hydraulic fracture, developing from a pressurized borehole, against the analytical Kristianovich-Geertsma-de Klerk (KGD) solution. INTRODUCTION Numerically modeling tensile fracture propagation is of great interest in reservoir engineering (Chuprakov et al., 2011; Dahi-Taleghani and Olson, 2011; Jiang et al., 2015). Under in-situ stress conditions, natural rock failures are mostly in shear modes, such as fault activation, while tensile failures are sometimes attributed to magma/dike intrusions (Rivalta and Dahm, 2006; Aydin et al., 2006; Rutqvist et al., 2008). Induced tensile failure, typically hydraulic fracturing, has been widely used to enhance tight reservoirs’ permeability and greatly made unconventional hydrocarbon and geothermal resources accessible (Rubinstein and Mahani, 2015; Li et al., 2019). Several numerical methods have been applied to model hydraulic fracturing, such as the cohesive-zone method, extended finite-element method, and boundary-element method (Chen et al., 2021; Jin, 2018). We extend a well established traction-at-split-node (TSN) method, which has a strong track record for modeling dynamic fault ruptures (Day et al., 2005; Dalguer and Day, 2007), to model tensile failures.
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Gwiazda, Jane, Joseph Bauer, and Frank Thorn. "Accommodation, phorias, and AC/A ratios in school-age children." In Vision Science and its Applications. Washington, D.C.: Optica Publishing Group, 1996. http://dx.doi.org/10.1364/vsia.1996.sac.2.

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Changes in the interactions between accommodation and vergence have been linked to the development of myopia in adults. Jiang (1995) reported that AC/A (accommodative convergence/ accommodation) ratios of young adults who became myopic over a 2 to 3 year period were higher at the outset than those of subjects who remained emmetropic. Previously we reported that newly myopic children show insufficient accommodative response to blur (Gwiazda et al, 1993). We have speculated that this accommodative lag might create a blurred image on the retina when an individual is engaged in near work, which could induce myopia, as occurs with animal models. Reduced accommodation could also account for elevated AC/A ratios in myopes.
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Yutang Xiao, Zhijian He, Yao Wang, and Liyan Niu. "Comparative study between the river of Tianjin airport industrial zone and Wei Jin Road river." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5964705.

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Peng, S. Y., X. B. Li, G. Q. Chen, and Y. Mitani. "Unloading Response of Tunnels in Deep Brittle Rock Mass Considering Ubiquitous Minor Joints." In 57th U.S. Rock Mechanics/Geomechanics Symposium. ARMA, 2023. http://dx.doi.org/10.56952/arma-2023-0360.

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ABSTRACT Minor joints exist ubiquitously in deep-buried brittle rock masses subjected to high in-situ stress. These joints affect the strength and deformation properties and lead to the concentration and dissipation of stress wave propagation. Through modeling and verification, the rock mass model in the study with closable minor joints can perform the plasto-elastic behavior under static compression, and the increase of wave velocity with confining stress under dynamic load. The unloading response of tunnels is analyzed in two influencing factors: unloading rate and lateral stress coefficient. According to the results, the increase of unloading rate will intensify stress oscillation and increase additional dynamic stress disturbance of the joint rock mass near the tunnel boundary. As the vibration dissipates kinetic energy, the additional dynamic stress disturbance farther away from the tunnel boundary is decreased. Additionally, the minor joints can open or close in particular directions depending on the complex in-situ stress and the stress distribution of the surrounding rock mass. At the location along the direction of open joints and close to the stress release source, the joint rock mass may have a higher additional stress concentration than in the elastic model. INTRODUCTION The scarcity of shallow mineral resources and construction space has substantially escalated the depth of tunnel excavation (Li et al., 2017; Xie et al., 2015). Deep rock mass subjected to gravitational and tectonic stress reserves enormous strain energy and exhibits evident fracture development. Deep tunnel excavation is typically a dynamic unloading process (Cai, 2008; Lu et al., 2012). In particular, the strain energy will be immediately released within several milliseconds and induce a pulse load when the tunnel is excavated utilizing drilling and blasting (Yang et al., 2013). This process may lead to various observed hazard phenomena, such as spalling (Jiang et al., 2013), rock burst (Ortlepp & Stacey, 1994), large deformation (He et al., 2005), and zonal disintegration (Jia & Zhu, 2015). Meanwhile, the intensity and frequency of disasters escalate as excavation depth increases, threatening construction and operation safety (Cai, 2016). Therefore, the mechanism of unloading failure of deep tunnels in rock mass has always attracted the attention of many researchers.
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Shao, Changzong. "Discussion on the Humanities and Artistry of Buddhist Sculptures in Wei, Jin, Southern and Northern Dynasties." In 7th International Conference on Arts, Design and Contemporary Education (ICADCE 2021). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210813.008.

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Yang, Qun. "Revisiting the Metaphysical Verses of Wei and Jin Dynasties: The Combination of Philosophical Discourse and Literary Discourse." In 6th International Conference on Social Science, Education and Humanities Research (SSEHR 2017). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/ssehr-17.2018.20.

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Reports on the topic "Wen jian"

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Jorgensen, Eric L. Proposed Web-Based Joint IETM Architecture (JIA) for the Interoperability of DoD IETMs. Fort Belvoir, VA: Defense Technical Information Center, August 1998. http://dx.doi.org/10.21236/ada446483.

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Jorgensen, Eric L. Proposed DoD Guidelines for Implementation of a Web-Based Joint IETM Architecture (JIA) to Assure the Interoperability of DoD IETMs. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada445821.

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Farahbod, A. M., and J. F. Cassidy. An overview of seismic attenuation in the Northern Appalachians Seismic Zone, New Brunswick and Nova Scotia. Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/329702.

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In this study we investigated coda-wave attenuation (QC) from the northern Appalachian region of eastern Canada in the two provinces of New Brunswick and Nova Scotia. We used earthquake recordings from 8 broadband and 2 short period seismograph stations of the Canadian National Seismograph Network (CNSN) across the region. Our dataset is comprised of 476 earthquakes recorded between 1983 and 2021 with magnitudes ranging from 1.5 to 4.1, depths from 0 to 20 km (with the vast majority being &amp;lt;10 km) and epicentral distances of 5 to 100 km. This gives a total of 261 high signalto- noise (S/N) traces (S/N greater than or equal to 5.0) useful for QC calculation (with a maximum ellipse parameter, a2, of 100) across the region. Coda windows were selected to start at tc = 2tS (two times the travel time of the direct S wave), and were filtered at center frequencies of 2, 4, 8, 12 and 16 Hz. Our study reveals a consistent pattern. We find that in the northern New Brunswick, the lowest Q0 values (e.g., Q0 of 61) are at station KLN which is the closest station to the epicenter of the 1982 Miramichi earthquake (M 5.8). The highest Q0 values that we find (e.g., Q0 of 178) are at station GGN, located in the southern New Brunswick. Smaller Q0 values for stations in the north (closer to the Charlevoix-Kamouraska seismic zone or Miramichi source area) is explained by Jin and Aki's (1988) finding that Q0 is lower in the vicinity of large earthquakes. An average for all the data results in a Q relationship of QC = 99f0.96 for the frequency band of 2 to 16 Hz for the entire region.
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Farahbod, A. M., and J. F. Cassidy. An overview of seismic attenuation in the Charlevoix Seismic Zone, southern Quebec. Natural Resources Canada/CMSS/Information Management, 2023. http://dx.doi.org/10.4095/332158.

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We investigate seismic attenuation characteristics of the Charlevoix Seismic Zone. This zone is located ~100 km downstream from Quebec City and is the most seismically active region of eastern Canada. We used earthquake recordings from 8 seismograph stations of the Canadian National Seismic Network (CNSN) across the region. Our dataset is comprised of 584 earthquakes recorded between 1992 and 2022 with magnitudes ranging from 2.0 to 5.4, depths from 0 to 30 km and epicentral distances of 5 to 100 km. This gives a total of 1490 high signal-to-noise (S/N) traces (S/N?5.0) useful for QC calculation (with a maximum ellipse parameter, a2, of 100) across the region. Coda windows were selected to start at tc = 2tS (two times the travel time of the direct S wave), and were filtered at center frequencies of 2, 4, 8, 12 and 16 Hz. Our study reveals a consistent pattern. We find that the highest Q0 (Q at 1 Hz) values are at station A11 (e.g., Q0 of 109), that is the farthest station from the 1663, M~7 earthquake (D=40 km), excluding the new station of CACQ. The lowest Q0 values that we find are at the station A16 (e.g., Q0 of 72) that is the second closest station to the epicenter of the 1663 earthquake (D=16 km) after station A61 (D=10 km). Also, we find the lowest overall average Q0 values at station A16 (e.g., Q0 of 72). In general, Q0 is lower in the vicinity of large earthquakes (Jin &amp; Aki, 1988). Therefore, the low Q0 values at station A16 may suggest that the 1663 earthquake is located slightly southeast of the catalog epicenter, considering high uncertainty associated with historic events. An average for all the data results in a Q relationship of QC = 81f1.06 for the frequency band of 2 to 16 Hz for the entire region.
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