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Journal articles on the topic 'West African ZIKV'

Author: Grafiati

Published: 7 December 2024

Last updated: 31 July 2025

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1

Machmouchi, Dana, Marie-Pierre Courageot, Chaker El-Kalamouni, Alain Kohl, and Philippe Desprès. "Replication properties of a contemporary Zika virus from West Africa." PLOS Neglected Tropical Diseases 18, no. 7 (2024): e0012066. http://dx.doi.org/10.1371/journal.pntd.0012066.

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Zika virus (ZIKV) has become a global health problem over the past decade due to the extension of the geographic distribution of the Asian/American genotype. Recent epidemics of Asian/American ZIKV have been associated with developmental disorders in humans. There is mounting evidence that African ZIKV may be associated with increased fetal pathogenicity necessitating to pay a greater attention towards currently circulating viral strains in sub-Saharan Africa. Here, we generated an infectious molecular clone GUINEA-18 of a recently transmitted human ZIKV isolate from West Africa, ZIKV-15555. T

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2

Machmouchi, Dana, Marie-Pierre Courageot, Eva Ogire, et al. "The NS1 protein of contemporary West African Zika virus potentiates viral replication and reduces innate immune activation." PLOS Neglected Tropical Diseases 18, no. 8 (2024): e0012146. http://dx.doi.org/10.1371/journal.pntd.0012146.

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Mosquito-borne Zika virus (ZIKV) from sub-Saharan Africa has recently gained attention due to its epidemic potential and its capacity to be highly teratogenic. To improve our knowledge on currently circulating strains of African ZIKV, we conducted protein sequence alignment and identified contemporary West Africa NS1 (NS1CWA) protein as a highly conserved viral protein. Comparison of NS1CWA with the NS1 of the historical African ZIKV strain MR766 (NS1MR766), revealed seven amino acid substitutions. The effects of NS1 mutations on protein expression, virus replication, and innate immune activat

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3

Rawlinson, William. "Pregnancy, the placenta and Zika virus (ZIKV) infection." Microbiology Australia 37, no. 4 (2016): 170. http://dx.doi.org/10.1071/ma16057.

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Zika virus (ZIKV) infections have been recognised in Africa and Asia since 1940. The virus is in the family Flaviviridae and genus Flavivirus, along with Dengue, Japanese encephalitis virus, Tick borne encephalitis, West Nile virus, and Yellow fever virus. These viruses share biological characteristics of an envelope, icosahedral nucleocapsid, and a non-segmented, positive sense, single-strand RNA genome of ~10kb encoding three structural proteins (capsid C pre-membrane/membrane PrM/M, envelope E), and seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5). ZIKV has three kno

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4

Rose, Noah H., Stéphanie Dabo, Silvânia da Veiga Leal, et al. "Enhanced mosquito vectorial capacity underlies the Cape Verde Zika epidemic." PLOS Biology 20, no. 10 (2022): e3001864. http://dx.doi.org/10.1371/journal.pbio.3001864.

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The explosive emergence of Zika virus (ZIKV) across the Pacific and Americas since 2007 was associated with hundreds of thousands of human cases and severe outcomes, including congenital microcephaly caused by ZIKV infection during pregnancy. Although ZIKV was first isolated in Uganda, Africa has so far been exempt from large-scale ZIKV epidemics, despite widespread susceptibility among African human populations. A possible explanation for this pattern is natural variation among populations of the primary vector of ZIKV, the mosquito Aedes aegypti. Globally invasive populations of Ae. aegypti

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5

Park, Jooyeon, Jinhwa Jang, and Insung Ahn. "Comparison of Genetic Variations in Zika Virus Isolated From Different Geographic Regions." International Journal of Healthcare Information Systems and Informatics 14, no. 3 (2019): 29–39. http://dx.doi.org/10.4018/ijhisi.2019070103.

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The Zika virus (ZIKV) belongs to the genus Flavivirus, together with Dengue virus, yellow fever virus, and West Nile virus. The virus, which was first found in Africa in 1947, has spread across the world owing to a lack of effective drugs or vaccines. The complete genome sequence of ZIKV is now available; it includes three structural and seven non-structure genes arranged in the order of capsid, pre-membrane, envelope, NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5. Two geographically distinct lineages are known, i.e., Asian and African, but ZIKV exhibits differences in clinical progression among r

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6

Majumder, Maimuna S., Rosanna Hess, Ratchneewan Ross, and Helen Piontkivska. "Seasonality of birth defects in West Africa: could congenital Zika syndrome be to blame?" F1000Research 7 (February 7, 2018): 159. http://dx.doi.org/10.12688/f1000research.13858.1.

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The link between Zika virus infection during pregnancy and microcephaly and other neurodevelopmental defects in infants, referred to as congenital Zika syndrome (CZS), was recently discovered. One key question that remains is whether such neurodevelopmental abnormalities are limited to the recently evolved Asiatic ZIKV strains or if they can also be induced by endemic African strains. Thus, we examined birth registries from one particular hospital from a country in West Africa, where ZIKV is endemic. Results showed a seasonal pattern of birth defects that is consistent with potential CZS, whic

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7

Majumder, Maimuna S., Rosanna Hess, Ratchneewan Ross, and Helen Piontkivska. "Seasonality of birth defects in West Africa: could congenital Zika syndrome be to blame?" F1000Research 7 (July 19, 2018): 159. http://dx.doi.org/10.12688/f1000research.13858.2.

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The link between Zika virus infection during pregnancy and microcephaly and other neurodevelopmental defects in infants, referred to as congenital Zika syndrome (CZS), was recently discovered. One key question that remains is whether such neurodevelopmental abnormalities are limited to the recently evolved Asiatic ZIKV strains or if they can also be induced by endemic African strains. Thus, we examined birth registries from one particular hospital from a country in West Africa, where ZIKV is endemic. Results showed a seasonal pattern of birth defects that is consistent with potential CZS, whic

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8

Bayandin, Roman B., Marat T. Makenov, Sanaba Boumbaly, et al. "The First Case of Zika Virus Disease in Guinea: Description, Virus Isolation, Sequencing, and Seroprevalence in Local Population." Viruses 15, no. 8 (2023): 1620. http://dx.doi.org/10.3390/v15081620.

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The Zika virus (ZIKV) is a widespread mosquito-borne pathogen. Phylogenetically, two lineages of ZIKV are distinguished: African and Asian–American. The latter became the cause of the 2015–2016 pandemic, with severe consequences for newborns. In West African countries, the African lineage was found, but there is evidence of the emergence of the Asian–American lineage in Cape Verde and Angola. This highlights the need to not only monitor ZIKV but also sequence the isolates. In this article, we present a case report of Zika fever in a pregnant woman from Guinea identified in 2018. Viral RNA was

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9

Dabo, Stéphanie, Annabelle Henrion-Lacritick, Alicia Lecuyer, et al. "Extensive variation and strain-specificity in dengue virus susceptibility among African Aedes aegypti populations." PLOS Neglected Tropical Diseases 18, no. 3 (2024): e0011862. http://dx.doi.org/10.1371/journal.pntd.0011862.

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African populations of the mosquito Aedes aegypti are usually considered less susceptible to infection by human-pathogenic flaviviruses than globally invasive populations found outside Africa. Although this contrast has been well documented for Zika virus (ZIKV), it is unclear to what extent it is true for dengue virus (DENV), the most prevalent flavivirus of humans. Addressing this question is complicated by substantial genetic diversity among DENV strains, most notably in the form of four genetic types (DENV1 to DENV4), that can lead to genetically specific interactions with mosquito populat

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10

Venkateswaran, Neeraja, Jawad Sarwar, Nishnath Parameswaran, et al. "Development and testing of a novel multiplex serodiagnostic assay for Zika and other arboviruses." Journal of Immunology 198, no. 1_Supplement (2017): 81.26. http://dx.doi.org/10.4049/jimmunol.198.supp.81.26.

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Abstract Human immunoglobulin (IgM) antibody capture enzyme linked immunosorbent assay (MAC-ELISA) is recommended by US Centers for Disease Control (CDC) to detect the Zika Virus (ZIKV) infection in samples collected after few days of the onset of disease. However, the cross-reactivity of IgM and immunoglobulin G (IgG) antibodies to ZIKV with dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV) and some other related flaviviruses poses a significant challenge for an accurate detection of ZIKV infection in a singleplex serological assay. To overcome these challenges we developed

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11

Gwon, Yong-Dae, Mårten Strand, Richard Lindqvist, et al. "Antiviral Activity of Benzavir-2 against Emerging Flaviviruses." Viruses 12, no. 3 (2020): 351. http://dx.doi.org/10.3390/v12030351.

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Most flaviviruses are arthropod-borne viruses, transmitted by either ticks or mosquitoes, and cause morbidity and mortality worldwide. They are endemic in many countries and have recently emerged in new regions, such as the Zika virus (ZIKV) in South-and Central America, the West Nile virus (WNV) in North America, and the Yellow fever virus (YFV) in Brazil and many African countries, highlighting the need for preparedness. Currently, there are no antiviral drugs available to treat flavivirus infections. We have previously discovered a broad-spectrum antiviral compound, benzavir-2, with potent

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12

Joannides, Joannitta, Mawuli Dzodzomenyo, Faustus Azerigyik, et al. "Species composition and risk of transmission of some Aedes-borne arboviruses in some sites in Northern Ghana." PLOS ONE 16, no. 6 (2021): e0234675. http://dx.doi.org/10.1371/journal.pone.0234675.

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Aedes-borne viral diseases mainly Yellow Fever (YF), Dengue (DEN), Zika (ZIK) and Chikungunya (CHK) have contributed to many deaths’ in the world especially in Africa. There have been major outbreaks of these diseases in West Africa. Although, YF outbreaks have occurred in Ghana over the years, no outbreak of DEN, ZIK and CHK has been recorded. However, the risk of outbreak is high due to its proximity to West African countries where outbreaks have been recently been recorded. This study surveyed the mosquito fauna to assess the risk of transmission of Yellow fever (YFV), Dengue (DENV), Chikun

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Kading, Rebekah C., Robert M. Kityo, Eric C. Mossel, et al. "Neutralizing antibodies against flaviviruses, Babanki virus, and Rift Valley fever virus in Ugandan bats." Infection Ecology & Epidemiology 8, no. 1 (2018): 1439215. https://doi.org/10.5281/zenodo.14820192.

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(Uploaded by Plazi for the Bat Literature Project) Introduction: A number of arboviruses have previously been isolated from naturally-infected East African bats, however the role of bats in arbovirus maintenance is poorly understood. The aim of this study was to investigate the exposure history of Ugandan bats to a panel of arboviruses. Materials and methods: Insectivorous and fruit bats were captured from multiple locations throughout Uganda during 2009 and 2011-2013. All serum samples were tested for neutralizing antibodies against West Nile virus (WNV), yellow fever virus (YFV), dengue 2 vi

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14

Idris, A. N., Whong, C. M. Z., and Abdulkadir, B. "Historical Trend and Epidemiology of Zika Virus." UMYU Journal of Microbiology Research (UJMR) 2, no. 2 (2017): 153–61. http://dx.doi.org/10.47430/ujmr.1722.023.

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Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses. In 2007 ZIKV caused an outbreak of relatively mild disease characterized by rash, arthralgia, and conjunctivitis on Yap Island in the south western Pacific Islands. Zika virus trend infection have been confirmed in several infants with microcephaly and in fetal losses in women infected during pregnancy. The virus can be prevented and control by sleeping under treated mosquito net to protect you from Mosquito bite. This was the first time that ZIKV was detected outside of Africa and

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15

Poungou, Natacha, Silas Lendzele Sevidzem, Aubin Armel Koumba, et al. "Mosquito-Borne Arboviruses Occurrence and Distribution in the Last Three Decades in Central Africa: A Systematic Literature Review." Microorganisms 12, no. 1 (2023): 4. http://dx.doi.org/10.3390/microorganisms12010004.

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Arboviruses represent a real public health problem globally and in the Central African subregion in particular, which represents a high-risk zone for the emergence and re-emergence of arbovirus outbreaks. Furthermore, an updated review on the current arbovirus burden and associated mosquito vectors is lacking for this region. To contribute to filling this knowledge gap, the current study was designed with the following objectives: (i) to systematically review data on the occurrence and distribution of arboviruses and mosquito fauna; and (ii) to identify potential spillover mosquito species in

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16

Marchi, Serena, Simonetta Viviani, Emanuele Montomoli, et al. "Zika Virus Epidemiology in Selected West African Countries between 2007 and 2012." Proceedings 50, no. 1 (2020): 100. http://dx.doi.org/10.3390/proceedings2020050100.

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Before its recent spread, serological investigations conducted between the 1960s and the 1990s showed the wide presence of Zika virus in Africa. According to the World Health Organization, the entire Africa continent is at risk of Zika outbreak due to the presence of the virus, competent vectors, and the low capacity for surveillance and containment of an epidemic. However, limited data are available on the recent prevalence in the African population. The aim of this study was to evaluate the immunity against Zika virus in samples of a selected cohort from West Africa, in order to investigate

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Marchi, Serena, Simonetta Viviani, Emanuele Montomoli, et al. "Zika Virus in West Africa: A Seroepidemiological Study between 2007 and 2012." Viruses 12, no. 6 (2020): 641. http://dx.doi.org/10.3390/v12060641.

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According to the World Health Organization, the entire African continent is at risk of a Zika outbreak. To increase data availability on the epidemiology of Zika virus circulation in Africa, we evaluated the immunity to Zika virus in a selected cohort of subjects from West Africa between 2007 and 2012. Human serum samples were collected in 2007 and in 2011/2012 from a cohort of 2–29-year-old subjects from Mali, Senegal, and The Gambia. A sample that tested positive by Zika virus IgG ELISA and by Zika virus microneutralization test was defined as positive. In 2007, the highest prevalence was 21

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18

Khatri, Sweety, Chandni Dhanoriya, and Deepak Kumar Jain. "Zika virus (ZIKV) disease: past, present and future." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 320–27. http://dx.doi.org/10.22270/jddt.v8i6-s.2076.

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The mosquito-borne arbovirus Zika virus (positive-stranded RNA virus, ZIKV, Flavivirus, Flaviviridae), has caused an outbreak imposing by its extent and quick spread. This became the focus of a current pandemic and public health crisis all around the world because of the incessant geographic growth of both the virus and its mosquito vectors; it is often misdiagnosed with other disease like yellow fever, west nile, dengue and chikungunya because of same clinical manifestation. After unprecedented huge scale outbreak of ZIKV in Pacific, Micronesian island of Yap in 2007, though ZIKV infections a

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Tinto, Bachirou, Didier Patindé Alexandre Kaboré, Dramane Kania, et al. "Serological Evidence of Zika Virus Circulation in Burkina Faso." Pathogens 11, no. 7 (2022): 741. http://dx.doi.org/10.3390/pathogens11070741.

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Zika virus (ZIKV) and dengue virus (DENV) are two closely related members of the Flaviviridae family, both transmitted by mosquitoes of the genus Aedes, and are among the arboviruses most at risk to human health. Burkina Faso has been facing an upsurge in DENV outbreaks since 2013. Unlike DENV, there is no serological evidence of ZIKV circulation in humans in Burkina Faso. The main objective of our study was to determine the seroprevalence of ZIKV and DENV in blood donors in Burkina Faso. A total of 501 donor samples collected in the two major cities of the country in 2020 were first tested by

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Schultz, Emily M., TyAnthony J. Jones, Hannah K. Hopkins, Jingmei Zeng, and Kelli L. Barr. "Post-Vaccination Yellow Fever Antiserum Reduces Zika Virus in Embryoid Bodies When Placental Cells are Present." Vaccines 8, no. 4 (2020): 752. http://dx.doi.org/10.3390/vaccines8040752.

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Zika virus (ZIKV) is a flavivirus that originated in Africa but emerged in Latin America in 2015. In this region, other flaviviruses such as Dengue (DENV), West Nile, and Yellow Fever virus (YFV) also circulate, allowing for possible antigenic cross-reactivity to impact viral infections and immune responses. Studies have found antibody-mediated enhancement between DENV and ZIKV, but the impact of YFV antibodies on ZIKV infection has not been fully explored. ZIKV infections cause congenital syndromes, such as microcephaly, necessitating further research into ZIKV vertical transmission through t

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Gatherer, Derek. "The voyages of Zika virus." Microbiology Australia 37, no. 4 (2016): 206. http://dx.doi.org/10.1071/ma16067.

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The announcement in May this year from the World Health Organization, that the Zika virus outbreak that began in October 2015 in the Cape Verde Islands off the west coast of Africa was an American variant of Zika virus, confirmed that Zika has now circumnavigated the world.

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Agboli, Eric, Julien B. Z. Zahouli, Athanase Badolo, and Hanna Jöst. "Mosquito-Associated Viruses and Their Related Mosquitoes in West Africa." Viruses 13, no. 5 (2021): 891. http://dx.doi.org/10.3390/v13050891.

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Mosquito-associated viruses (MAVs), including mosquito-specific viruses (MSVs) and mosquito-borne (arbo)viruses (MBVs), are an increasing public, veterinary, and global health concern, and West Africa is projected to be the next front for arboviral diseases. As in-depth knowledge of the ecologies of both western African MAVs and related mosquitoes is still limited, we review available and comprehensive data on their diversity, abundance, and distribution. Data on MAVs’ occurrence and related mosquitoes were extracted from peer-reviewed publications. Data on MSVs, and mosquito and vertebrate ho

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Bache, Emmanuel, Marguerite M. Loembe, and Selidji T. Agnandji. "PO 8581 ZOONOTIC VIRAL ANTIGENS SURVEILLANCE IN HEALTHY POPULATIONS LIVING IN LAMBARÉNÉ, GABON." BMJ Global Health 4, Suppl 3 (2019): A58.2—A58. http://dx.doi.org/10.1136/bmjgh-2019-edc.153.

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BackgroundWorldwide, viral zoonotic infections such as filoviruses, flaviviruses, nairoviruses and arenaviruses cause self-limiting to severe diseases. They are endemic in sub-Saharan Africa, causing sporadic outbreaks warranting the development of sustainable surveillance systems. In Gabon, Ebola outbreaks occurred from 1994 to 2002 causing 214 human cases and 150 deaths, while Dengue, Zika and Chikungunya virus outbreaks occurred between 2007 and 2010. Beyond these outbreaks, little is known about the epidemiology. Recently, in collaboration with the Japanese government, the Research and Hea

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Falade, Bankole. "Religious and Traditional Belief Systems Coexist and Compete with Science for Cultural Authority in West Africa." Cultures of Science 2, no. 1 (2019): 9–22. http://dx.doi.org/10.1177/209660831900200102.

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This study examines the coexistence of science with Christian, Islamic and African religious beliefs and its implications for science communication. Using Moscovici's social representations theory and focusing on his accommodation hypothesis, the paper draws from experiences in mental health care, vaccination controversies and viral epidemics using case studies from West Africa. It also draws similarities from historical vaccination controversies around the world and the Zika virus epidemic in Brazil. The paper shows that Moscovici's accommodation hypothesis of cognitive polyphasia better expl

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Sheikh, Farooq A. "Uphill Task: Can We Ever Conquer Against New Emerging Viruses?" JMS SKIMS 20, no. 2 (2017): 109–10. http://dx.doi.org/10.33883/jms.v20i2.207.

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Every time there is a major infectious disease outbreak that scares us, such as Ebola in West Africa, Middle East Respiratory Syndrome (MERS) on the Arabian Peninsula and South Africa, and Zika virus in South and Central America and the Caribbean; this time arising from a mosquito-borne agent that has spread stealth around the globe [ 1]. It remains one of the great mysteries of the Zika epidemic: Why did a virus that existed for decades elsewhere in the world suddenly seem to become more destructive when it landed in Latin America? An intriguing study in mice, which has prompted some skeptici

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Gatherer, Derek. "Emerging viruses – is there an emerging pattern?" Biochemist 39, no. 3 (2017): 4–7. http://dx.doi.org/10.1042/bio03903004.

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The Ebola outbreak in West Africa in 2014 and the spread of Zika across the Americas in 2016 have thrust previously obscure viruses into the media spotlight. But is something new really going on? What can we expect in future? Is there anything we can do?

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To, Albert, Varney M. Kamara, Davidetta M. Tekah, et al. "Baseline Seroprevalence of Arboviruses in Liberia Using a Multiplex IgG Immunoassay." Tropical Medicine and Infectious Disease 10, no. 4 (2025): 92. https://doi.org/10.3390/tropicalmed10040092.

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Insect-borne viruses may account for a significant proportion of non-malaria and non-bacterial febrile illnesses in Liberia. Although the presence of many arthropod vectors has been documented, the collective burden of arbovirus infections and baseline pre-existing immunity remains enigmatic. Our goal was to determine the seroprevalence of arbovirus exposure across the country using a resource-sparing, multiplex immunoassay to determine IgG responses to immunodominant antigens. 532 human serum samples, from healthy adults, collected from 10 counties across Liberia, were measured for IgG reacti

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Varghese, Jano, Imesh De Silva, and Douglas Millar. "Latest Advances in Arbovirus Diagnostics." Microorganisms 11, no. 5 (2023): 1159. http://dx.doi.org/10.3390/microorganisms11051159.

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Arboviruses are a diverse family of vector-borne pathogens that include members of the Flaviviridae, Togaviridae, Phenuviridae, Peribunyaviridae, Reoviridae, Asfarviridae, Rhabdoviridae, Orthomyxoviridae and Poxviridae families. It is thought that new world arboviruses such as yellow fever virus emerged in the 16th century due to the slave trade from Africa to America. Severe disease-causing viruses in humans include Japanese encephalitis virus (JEV), yellow fever virus (YFV), dengue virus (DENV), West Nile virus (WNV), Zika virus (ZIKV), Crimean–Congo hemorrhagic fever virus (CCHFV), severe f

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Herrera, Bobby Brooke, Charlotte A. Chang, Donald J. Hamel, et al. "Continued Transmission of Zika Virus in Humans in West Africa, 1992–2016." Journal of Infectious Diseases 215, no. 10 (2017): 1546–50. http://dx.doi.org/10.1093/infdis/jix182.

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Bhatia, Bharti, Wakako Furuyama, Thomas Hoenen, Heinz Feldmann, and Andrea Marzi. "Ebola Virus Glycoprotein Domains Associated with Protective Efficacy." Vaccines 9, no. 6 (2021): 630. http://dx.doi.org/10.3390/vaccines9060630.

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Ebola virus (EBOV) is the cause of sporadic outbreaks of human hemorrhagic disease in Africa, and the best-characterized virus in the filovirus family. The West African epidemic accelerated the clinical development of vaccines and therapeutics, leading to licensure of vaccines and antibody-based therapeutics for human use in recent years. The most widely used vaccine is based on vesicular stomatitis virus (VSV) expressing the EBOV glycoprotein (GP) (VSV-EBOV). Due to its favorable immune cell targeting, this vaccine has also been used as a base vector for the development of second generation V

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Chappatte, André. "When silence is “yeelen” (light): Exploring the corporeality of the mind in a nocturnal solo zikr practice (Odienné, Ivory Coast)." Critical Research on Religion 9, no. 2 (2021): 175–90. http://dx.doi.org/10.1177/2050303220986982.

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In the town of Odienné (Ivory Coast), Madou forges his faith in God by performing long sessions of solo zikr (recollection of God) after midnight. This article ethnographically explores the theme of light in this Sufi practice of concentration as an experiential form of being. It first describes how the light and darkness of the penumbra of the night co-initiate what I call “the devotional place” of zikr. Following a phenomenological writing, it then describes how, as hours go by, Madou’s concentration navigates towards “ yeelen” (spiritual light) through the silence of the deep night. In doin

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Ali, P. Shaik Syed. "Epidemiology of emerging viruses." Indian Journal of Microbiology Research 10, no. 3 (2023): 116–22. http://dx.doi.org/10.18231/j.ijmr.2023.021.

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Newly emerging viruses such as West Nile virus, coronaviruses (SARS-CoV, MERS-CoV and SARS-CoV-2), H1N1pdm09, Ebola virus, Zika virus and Monkeypox virus are of global concern as they have caused serious public threats. Among the several outbreaks caused by emerging viruses, the worst pandemic was caused by SARS-CoV-2. The Omicron variant is the dominant variant among SARS-CoV-2 variants and the lineages BA.5.2 and BF.7 were responsible for the recent Chinese surge. Genome sequencing studies of MERS-CoV revealed that it is evolving with mutations in spike protein. West Nile virus is still circ

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Pinto Junior, Vitor Laerte, Kleber Luz, Ricardo Parreira, and Paulo Ferrinho. "Vírus Zika: Revisão para Clínicos." Acta Médica Portuguesa 28, no. 6 (2015): 760. http://dx.doi.org/10.20344/amp.6929.

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Zika virus is a flavivirus related to Dengue virus, yellow fever virus and West Nile virus. It is considered an emerging arbovirus transmitted by mosquitos of the genus Aedes. Its first description took place in 1947 in the Zika Forest in Uganda, isolated on Rhesus monkey used as bait to study the yellow fever virus. Sporadic cases have been detected in African countries and at the end of the 70’s in Indonesia. In 2007, epidemics were described in Micronesia and other islands in the Pacific Ocean and more recently in Brazil. Clinical picture is characterized as a ‘dengue-like’ syndrome, with a

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Mohulatsi, Makgake Ziphorah, Tendayi Clotilda Garutsa, and Boipelo Bahule. "The Experiences of Expectant and New Mothers in Accessing Maternal Healthcare Services during the COVID-19 Pandemic in Mmabatho, North-West, South Africa." Social Sciences 12, no. 7 (2023): 381. http://dx.doi.org/10.3390/socsci12070381.

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Access to maternal healthcare has been a challenge for women of African descent. Similarly, to previous illness outbreaks such as the Ebola and Zika outbreaks, the Coronavirus pandemic effects vary from one demographic group to another. Women, compared to men, are left in a more vulnerable position due to long-existing social inequalities and disparities. Differentiated effects include, amongst others, access to health and healthcare, risk of infection and coping strategies. This study examined the experiences of expectant and new mothers in accessing maternal healthcare services during the CO

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Grubaugh, Nathan D., and Kristian G. Andersen. "Navigating the Zika panic." F1000Research 5 (August 4, 2016): 1914. http://dx.doi.org/10.12688/f1000research.9370.1.

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The epidemics of Ebola virus in West Africa and Zika virus in America highlight how viruses can explosively emerge into new territories. These epidemics also exposed how unprepared we are to handle infectious disease emergencies. This is also true when we consider hypothesized new clinical features of infection, such as the associations between Zika virus infection and severe neurological disease, including microcephaly and Guillain-Barré syndrome. On the surface, these pathologies appear to be new features of Zika virus infection, however, causal relationships have not yet been established. D

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Lounibos, L. Phil, Barry W. Alto, Nathan D. Burkett-Cadena, et al. "Zika, a Mosquito-Transmitted Virus." EDIS 2016, no. 1 (2016): 7. http://dx.doi.org/10.32473/edis-in1120-2016.

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Zika is a mosquito-transmitted virus that has spread broadly in tropical regions and caused epidemics, especially in the past 8 to 9 years. In its native range in West Africa and Uganda, the Zika virus stays in the forest for the most part, and human infections are considered incidental and medically inconsequential. In 2015, however, Zika became a larger concern when a strain of the virus traced to outbreaks in French Polynesia emerged in northeastern Brazil. This strain provoked alarm because of increased incidence of microcephaly in babies born to Zika-infected mothers. Local transmission,

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Klasing, Amanda M. "COVID-19, Gender, and Intersectional Discrimination: Can the Promise of International Human Rights Meet the Moment?" Proceedings of the ASIL Annual Meeting 114 (2020): 377–81. http://dx.doi.org/10.1017/amp.2021.71.

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Human rights documentation around the world has shown that crises disproportionately or distinctly impacts women and girls, whether conflict or natural disaster-related. This is true for disease outbreaks as well. Human Rights Watch has raised the concerns about the gendered impacts of the Ebola virus outbreaks in West Africa, or the human rights dimensions of the Zika virus impacts in northeast Brazil. The COVID-19 pandemic and response are no different. We are already seeing the disproportionate and gendered ways government responses to the pandemic are generating harm to women and girls and

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Lendak, Dajana, Tomislav Preveden, Nadica Kovacevic, Slavica Tomic, Maja Ruzic, and Milotka Fabri. "Novel infectious diseases in europe." Medical review 70, no. 11-12 (2017): 385–90. http://dx.doi.org/10.2298/mpns1712385l.

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Introduction. The end of 20th and beginning of 21st century is marked by the discovery of new, supercontagious and fast spreading viral diseases. Since 1967, more than 40 new agents have been identified, including human immunodeficiency virus, Ebola, Marburg fever, severe acute respiratory syndrome, hepatitis C, hepatitis E viruses and Zika virus. Modern lifestyle, availability and speed of air traffic, migrations, as well as climate changes, enable faster spreading of infectious diseases from the regions that were hardly reachable. We selected a few diseases that raised the greatest attention

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Raulino, Raisa, Guillaume Thaurignac, Christelle Butel, et al. "Multiplex detection of antibodies to Chikungunya, O’nyong-nyong, Zika, Dengue, West Nile and Usutu viruses in diverse non-human primate species from Cameroon and the Democratic Republic of Congo." PLOS Neglected Tropical Diseases 15, no. 1 (2021): e0009028. http://dx.doi.org/10.1371/journal.pntd.0009028.

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Background Epidemic arbovirus transmission occurs among humans by mosquito bites and the sylvatic transmission cycles involving non-human primates (NHPs) still exists. However, limited data are available on the extent in NHPs infections and their role. In this study, we have developed and validated a high-throughput serological screening tool to study the circulation of multiple arboviruses that represent a significant threat to human health, in NHPs in Central Africa. Methodology/Principal findings Recombinant proteins NS1, envelope domain-3 (DIII) for the dengue (DENV), yellow fever (YFV), u

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Thabet, Hala S., Emadeldin Y. Fawaz, Kossi Badziklou, et al. "Preliminary Screening of Mosquito Spatial Distribution in Togo: With Special Focus on the Aedes (Diptera: Culicidae) Species." Journal of Medical Entomology 56, no. 4 (2019): 1154–58. http://dx.doi.org/10.1093/jme/tjz029.

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Abstract The Togolese Republic has a tropical and humid climate which constitutes an ideal environment for mosquitoes to breed and transmit diseases. The Aedes mosquito is known to transmit yellow fever (YF), dengue, chikungunya, and Zika viruses in West Africa. Togo has been suffering from YF virus transmission, despite vaccination efforts. Unfortunately, there is scarcity in the data that reflect mosquito spatial distribution in Togo, specifically possible YF vectors. In the current study, mosquito surveillance efforts targeted areas with confirmed YF cases between July and August 2012. Indo

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Nsabatien, Victoire, Josue Zanga, Fiacre Agossa, et al. "Data from Entomological Collections of Aedes (Diptera: Culicidae) in a post-epidemic area of Chikungunya, City of Kinshasa, Democratic Republic of Congo." Gigabyte 2023 (November 8, 2023): 1–7. http://dx.doi.org/10.46471/gigabyte.96.

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Arbovirus epidemics (chikungunya, dengue, West Nile fever, yellow fever and zika) are a growing threat in African areas where Aedes (Stegomyia) aegypti (Linnaeus, 1762) and Aedes albopictus (Skuse, 1895) are present. The lack of comprehensive sampling of these two vectors limits our understanding of their propagation dynamics in areas at risk of arboviruses. Here, we collected 6,943 observations (both larval and human capture) of Ae. aegypti and Ae. albopictus between 2020 and 2022. The study was carried out in the Vallee de la Funa, a post-epidemic zone in the city of Kinshasa, Democratic Rep

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Lucey, Daniel R. "Will Zika Virus and Microcephaly Epidemics Emerge After Ebola in West Africa? The Need for Prospective Studies Now." Health Security 14, no. 2 (2016): 53–54. http://dx.doi.org/10.1089/hs.2016.0033.

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BABA, S. S., A. H. FAGBAMI, and O. D. OLALEYE. "ANTIGENIC RELATEDNESS OF SELECTED FLAVIVIRUSES: STUDY WITH HOMOLOGOUS AND HETEROLOGOUS IMMUNE MOUSE ASCITIC FLUIDS." Revista do Instituto de Medicina Tropical de São Paulo 40, no. 6 (1998): 343–49. http://dx.doi.org/10.1590/s0036-46651998000600002.

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The antigenic relationship of 9 flaviviruses, Yellow fever (YF) , Wesselsbron (WSL) , Uganda S (UGS) , Potiskum (POT), West Nile (WN) , Banzi (BAN) , Zika (ZK) , Dengue type 1 (DEN-1) and Dengue type 2 (DEN-2), was assessed by cross-haemagglutination-inhibition (Cross-HI) and cross-complement fixation (Cross-CF) reactions between each of the viruses and their homologous immune mouse ascitic fluids. Titre ratios were calculated using the heterologous and homologous titres. Cross-CF reactions revealed wider antigenic variations among viruses than Cross-HI reactions. There was no significant anti

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Raksakoon, Chadchalerm, and Rutcharin Potiwat. "Current Arboviral Threats and Their Potential Vectors in Thailand." Pathogens 10, no. 1 (2021): 80. http://dx.doi.org/10.3390/pathogens10010080.

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Arthropod-borne viral diseases (arboviruses) are a public-health concern in many regions of the world, including Thailand. This review describes the potential vectors and important human and/or veterinary arboviruses in Thailand. The medically important arboviruses affect humans, while veterinary arboviruses affect livestock and the economy. The main vectors described are mosquitoes, but other arthropods have been reported. Important mosquito-borne arboviruses are transmitted mainly by members of the genus Aedes (e.g., dengue, chikungunya, and Zika virus) and Culex (e.g., Japanese encephalitis

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Hery, Lyza, Antoine Boullis, Christelle Delannay, and Anubis Vega-Rúa. "Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)." Emerging Microbes & Infections 8, no. 1 (2019): 699–706. http://dx.doi.org/10.1080/22221751.2019.1615849.

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Salgueiro, Patrícia, Célia Serrano, Bruno Gomes, et al. "Phylogeography and invasion history of Aedes aegypti , the Dengue and Zika mosquito vector in Cape Verde islands (West Africa)." Evolutionary Applications 12, no. 9 (2019): 1797–811. http://dx.doi.org/10.1111/eva.12834.

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Böszörményi, Kinga, Janet Hirsch, Gwendoline Kiemenyi Kayere, et al. "A Bacterially-Expressed Recombinant Envelope Protein from Usutu Virus Induces Neutralizing Antibodies in Rabbits." Vaccines 9, no. 2 (2021): 157. http://dx.doi.org/10.3390/vaccines9020157.

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Background: Recently, an emerging flavivirus, Usutu virus (USUV), has caused an epidemic among birds in Europe, resulting in a massive die-off in Eurasian blackbirds. Currently found only in Europe and Africa, it can be envisioned that Usutu virus will follow the path of other flaviviruses, like West Nile virus and Zika virus, and will spread via its mosquito vectors and bird hosts to other parts of the world. Several cases of human infections by Usutu virus have already been published. Anticipating this spread, development of an efficacious vaccine would be highly desirable. Method: This stud

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Diouf, Babacar, Ibrahima Dia, Ndeye Marie Sene, El Hadji Ndiaye, Mawlouth Diallo, and Diawo Diallo. "Morphology and taxonomic status of Aedes aegypti populations across Senegal." PLOS ONE 15, no. 11 (2020): e0242576. http://dx.doi.org/10.1371/journal.pone.0242576.

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Aedes aegypti is the primary vector of dengue, Zika, yellow fever and chikungunya viruses to humans. In Africa, two subspecies, Ae. aegypti aegypti (Aaa) and Ae. aegypti formosus (Aaf) have been described. Until very recently, it was considered that the two forms were sympatric in East Africa and that only Aaf was present in Central and West Africa. However, recent data suggests that Aaa was also common in Senegal without any clear evidence of genetic differences with Aaf. This study was carried out in different Ae. aegypti populations from Senegal to better clarify their taxonomic status. The

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Blázquez, Ana-Belén, Miguel A. Martín-Acebes, Teresa Poderoso, and Juan-Carlos Saiz. "Relevance of oxidative stress in inhibition of eIF2 alpha phosphorylation and stress granules formation during Usutu virus infection." PLOS Neglected Tropical Diseases 15, no. 1 (2021): e0009072. http://dx.doi.org/10.1371/journal.pntd.0009072.

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Usutu virus (USUV) is an African mosquito-borne flavivirus closely related to West Nile, Japanese encephalitis, Zika, and dengue viruses. USUV emerged in 1996 in Europe, where quickly spread across the continent causing a considerable number of bird deaths and varied neurological disorders in humans, including encephalitis, meningoencephalitis, or facial paralysis, thus warning about USUV as a potential health threat. USUV replication takes place on the endoplasmic reticulum (ER) of infected cells, inducing ER stress and resulting in the activation of stress-related cellular pathways collectiv

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Jiang, Jingjing, Stephanie J. Ramos, Preeti Bangalore, et al. "Multivalent DNA Vaccines as a Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses." Viruses 13, no. 3 (2021): 382. http://dx.doi.org/10.3390/v13030382.

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The emergence of multiple concurrent infectious diseases localized in the world creates a complex burden on global public health systems. Outbreaks of Ebola, Lassa, and Marburg viruses in overlapping regions of central and West Africa and the co-circulation of Zika, Dengue, and Chikungunya viruses in areas with A. aegypti mosquitos highlight the need for a rapidly deployable, safe, and versatile vaccine platform readily available to respond. The DNA vaccine platform stands out as such an application. Here, we present proof-of-concept studies from mice, guinea pigs, and non-human primates for t

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