Relevant bibliographies by topics / Wet granulation technique

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Wet granulation technique'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Wet granulation technique"

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Zarekar Shivani Gulab, Raykar Sonali Dattu Zende Gauri Sampat, and Puranik Aboli K and Sanjay J. Ingle. "A review on the wet granulation technique and its modules." World Journal of Biology Pharmacy and Health Sciences 20, no. 2 (2024): 113–24. http://dx.doi.org/10.30574/wjbphs.2024.20.2.0836.

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Wet granulation is a processes that involves adding a liquid to a powder to create granule of a desired size and shape. Its used in many fields, including pharmaceutical, neutraceutical and zootechnics to improve the flowbility, compressibility, and dosage of powders. Their are different technique of wet granulation. Low shear wet granulation, which is a form of wet granulation, is an important unit operation in the pharmaceutical, detergent and food industries. The granulation mechanism for wet granulation include wetting and nucleation, consolidation and growth and attrition and breakage. Hi
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V., B. Khot* D.A. Bhagwat J. I. D'Souza S. S. Shelake S. V. Patil. "OPTIMIZATION OF GRANULATION TECHNIQUES FOR DEVELOPMENT OF TABLET DOSAGE FORM." Indo American Journal of Pharmaceutical Sciences 04, no. 12 (2017): 4626–39. https://doi.org/10.5281/zenodo.1123244.

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The purpose of this study was to optimize the best granulation techniques for development of tablet dosage form. The present study explains comparative study of different wet granulation techniques including Planetary mixer granulation, Rapid mixer granulation, Fluid bed granulation with Direct compression method. Similar formulations were used to evaluate Planetary mixer granulation, Rapid mixer granulation and Fluid bed granulation method. The granules prepared by different techniques were evaluated for particle size distribution, porosity, spherisity, bulk density, flow property and compres
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Souza, Tatiane Pereira de, José Luiz Gómez-Amoza, Ramón Martínez Pacheco, and Pedro Ros Petrovick. "Development of granules from Phyllanthus niruri spray-dried extract." Brazilian Journal of Pharmaceutical Sciences 45, no. 4 (2009): 669–75. http://dx.doi.org/10.1590/s1984-82502009000400009.

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The aim of this study was to develop granules from Phyllanthus niruri spray-dried extract using dry and wet granulation and to assess techniques to enable the production of granules with improved technological characteristics and yields. Granules were characterized by granulometry, reological parameters, compression and hygroscopic behavior. Independent of the granulation technique, technologically developed granules presented particle diameter, bulk and tapped densities and compressibility indexes suitable for a solid dosage form. The compression behavior showed plastic and fragmentary deform
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Ayalasomayajula, Lakshmi Usha, E. Radha Rani, A. V. S. Ksheera Bhavani, and A. Vyasa Murty. "Effect of Granulation Methods on Drug Release Studies in Sustained Release Matrix Tablets of a Poorly Soluble Drug prepared using Synthetic Polymers." Journal of Drug Delivery and Therapeutics 10, no. 3 (2020): 76–82. http://dx.doi.org/10.22270/jddt.v10i3.4073.

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Vomiting or emesis is the abnormal emptying of stomach and upper part of intestine through esophagus and mouth. It occurs due to stimulation of the emetic (vomiting) centre situated in the medulla oblongata. Domperidone, a D2 receptor antagonist has antiemetic and prokinetic action is used as a model drug in the present work to prepare Sustained release matrix tablets using various synthetic polymers like Eudragit and HPMC K15 M. The tablets are designed to have a pH dependent release profile in order to prevent initial drug release in the stomach to reduce the possible gastro-irritant and ulc
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Patra Ch, Niranjan, Satya Prakash Singn, Hemant Kumar P, and Vimala Devi M. "A Systematic Study on Flowability and Compressibility of Asparagus racemosus root Powder for Tablet Preparation." International Journal of Pharmaceutical Sciences and Nanotechnology 1, no. 2 (2008): 129–35. http://dx.doi.org/10.37285/ijpsn.2008.1.2.3.

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The dried root of Asparagus racemosus is widely used as mild antihypertensive and tranquilizer. The objective of the present research was to study the original flowability, compressibility and compactibility of Asparagus racemosus root powder and develop its tablet formulations by wet granulation and direct compression technology. The consolidation behavior of drug and tablet formulations were studied by using Heckel and Leuenberger equation. Asparagus racemosus root powder showed very poor flowability and compactibility. Kawakita analysis revealed improved flowability for formulations prepare
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Saeed, Humaira, Muhammad Ramzan, and Abid Hussain. "Effect of Polymer Type, Concentration and Formulation Technique on Mucoadhesive Strength and Swelling Index of Clarithromycin Tablets." Pharmaceutical Communications 2, no. 1 (2023): 19–29. http://dx.doi.org/10.55627/pharma.002.01.0281.

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This study aims to evaluate the effect of polymer type, concentration, and formulation technique on mucoadhesion and the Swelling Index of matrix tablets. Tablets were formulated by wet-granulation, solid dispersions, and direct compression techniques using different polymers in different concentrations (D:P 5:1, 5:2, and 5:3). Swelling Index and Mucoadhesive strength were analyzed for all the formulations (F1-15). The physicochemical parameters of the tablets were found to be within the acceptable limit. The swelling index for matrix tablets (F1-15) prepared by wet-granulations technique was
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SEVILLE. "Continuous Pharmaceutical Manufacture Using a Novel Wet Granulation Technique." Scientia Pharmaceutica 78, no. 3 (2010): 543. http://dx.doi.org/10.3797/scipharm.cespt.8.l03.

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Ni’matul Fauziah, Miftahul Maulidiyah, Silvia Nur Diana Putri, et al. "Review Artikel: Formulasi Tablet Menggunakan Metode Granulasi Basah." OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan 2, no. 4 (2024): 124–33. http://dx.doi.org/10.61132/obat.v2i4.535.

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Tablets are one of the most commonly used solid dosage forms of medicine in the pharmaceutical industry. The granulation process commonly used in making tablets is the wet granulation process. The operation method includes mixing the active ingredients and excipients, adding a binder liquid, forming granules, drying and sieving. The methods used in this research are literature research, journal reviews, and analysis of relevant papers carried out during the 2015-2023 period. The aim of this literature study is to determine the process, advantages, limitations and application of wet granulation
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Ying, Looi Shu, Mahibub Muhamadsaa Kanak, Noor Shahida Binti Ajmi, Vijay Kumar Methi, Rabia Basharat, and Lean Yen Loong. "Effect of Wet Granulation Technique on Preparation and Characterization of Piroxicam Inclusion Complexation." Caribbean Journal of Science and Technology 08, no. 01 (2020): 119–26. http://dx.doi.org/10.55434/cbi.2020.8108.

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The preparation of any pharmaceutical drug delivery system requires solubility as one of the top most requirements for active pharmaceutical ingredients. Inclusion Complexation has become popular in formulation development of water poor soluble active ingredients. In current study we have selected water poor soluble drug Piroxicam (PX) as the model active pharmaceutical ingredient. To release piroxicam drug from solid dosage forms such as tablets and capsules it requires improvement in its solubility prior to preparation of final dosage form. For large scale production and commercialization pr
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Kotamarthy, Lalith, Subhodh Karkala, Ashley Dan, Andrés D. Román-Ospino, and Rohit Ramachandran. "Investigating the Effects of Mixing Dynamics on Twin-Screw Granule Quality Attributes via the Development of a Physics-Based Process Map." Pharmaceutics 16, no. 4 (2024): 456. http://dx.doi.org/10.3390/pharmaceutics16040456.

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Twin-screw granulation (TSG) is an emerging continuous wet granulation technique that has not been widely applied in the industry due to a poor mechanistic understanding of the process. This study focuses on improving this mechanistic understanding by analyzing the effects of the mixing dynamics on the granule quality attributes (PSD, content uniformity, and microstructure). Mixing is an important dynamic process that simultaneously occurs along with the granulation rate mechanisms during the wet granulation process. An improved mechanistic understanding was achieved by identifying and quantif
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Dissertations / Theses on the topic "Wet granulation technique"

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Aksu, B., Anant R. Paradkar, Matas Marcel de, Ö. Özer, T. Güneri, and Peter York. "A quality by design approach using artificial intelligence techniques to control the critical quality attributes of ramipril tablets manufactured by wet granulation." 2012. http://hdl.handle.net/10454/10109.

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No<br>Quality by design (QbD) is an essential part of the modern approach to pharmaceutical quality. This study was conducted in the framework of a QbD project involving ramipril tablets. Preliminary work included identification of the critical quality attributes (CQAs) and critical process parameters (CPPs) based on the quality target product profiles (QTPPs) using the historical data and risk assessment method failure mode and effect analysis (FMEA). Compendial and in-house specifications were selected as QTPPs for ramipril tablets. CPPs that affected the product and process were used to est
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Books on the topic "Wet granulation technique"

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Vertommen, J. Pelletisation in a Rotary Processor Using the Wet Granulation Technique. Leuven University Press, 1998.

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Book chapters on the topic "Wet granulation technique"

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Shwetha, K., and B. V. Basavaraj. "Optimization of Vanillin Crosslinked Chitosan/Polycarbophil Superporous Hydrogel Hybrids Containing Tablets for Regulated Drug Delivery." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00523.

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Polysaccharides are most sustainable building blocks with improved characteristics for formulation of superporous hydrogels (SPH). Present research work emphasis on development and optimization of tablets comprising vanillin crosslinked chitosan/polycarbophil (CVP) SPH hybrids for regulated drug delivery. The formulation of CVP SPH hybrids were prepared using microwave irradiation with different concentrations of chitosan (polymer), vanillin (crosslinking agent) and polycarbophil (hybrid agent). Resultant formulation was subjected to FTIR, DSC, TGA, SEM and NMR characterization. Prepared CVP h
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Hasan, Nadeem. "Powders and Granules." In A Text Book of Pharmaceutics for I Year Diploma in Pharmacy. THINKPLUS PHARMA PUBLICATIONS, 2024. http://dx.doi.org/10.69613/t3k54808.

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Powders and granules are fundamental pharmaceutical forms used both as final dosage forms and as intermediates in the production of other solid dosage forms. This section explores the properties of powders, including particle size, shape, and surface area, and their impact on powder behavior and processing. Various methods of powder production, such as comminution and precipitation, are discussed. The principles of granulation, including wet and dry granulation techniques, are examined in detail, highlighting their role in improving powder flow properties and compressibility. Factors affecting
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Verma, Dr Garima, Dr Ajay Kumar Shukla, and Dr Vimal Kumar Yadav. "DOSAGE FORM DESIGN." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 7. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bapn7p1ch1.

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The design of dosage forms plays a critical role in the development and delivery of pharmaceutical products. It involves the careful selection and combination of excipients, drug substances, and manufacturing processes to create safe, effective, and patient-friendly dosage forms. This abstract provides an overview of the key considerations and principles involved in the design of dosage forms. The design process begins with a thorough understanding of the physicochemical properties of the drug substance, such as solubility, stability, and bioavailability. This knowledge guides the selection of
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Conference papers on the topic "Wet granulation technique"

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Sartor, G., A. Rich, D. Grimsey, M. White, and R. Forzatti. "Integrated process modelling for the Kalgoorlie Nickel Smelter." In 12th International Conference of Molten Slags, Fluxes and Salts (MOLTEN 2024) Proceedings. Australasian Institute of Mining and Metallurgy (AusIMM), 2024. http://dx.doi.org/10.62053/iudm4601.

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An in-depth process model was developed for the pyrometallurgical, off-gas systems and water balance of the Kalgoorlie Nickel Smelter. This model was used to assess plant capacity with changing concentrate grades, increased throughput and tighter environmental emissions under a range of potential future operating conditions. Comparison of modelled results allowed for flow sheet optimisation across a range of metrics including sustainability, processing capacity and costs. Process modelling software, METSIM® (ver 2020.06 by METSIM International), was used to simulate the flash furnace, integrat
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