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Journal articles on the topic 'Wharton’s jelly'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Amin, Sapna, Shripad Hebbar, Deepika Pothakamuri, and Prashant Adiga. "Significance of Wharton’s jelly area in prediction of aberrant foetal growth." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 7 (2018): 2820. http://dx.doi.org/10.18203/2320-1770.ijrcog20182888.

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Background: Size of the baby at the time birth determines its outcome. Low birth weight babies have their own set of problems such as respiratory distress syndrome, hypoxic ischemic encephalopathy, metabolic derangements and high rates of admission to intensive care units. On the other hand too large babies may cause difficulty in vaginal births, higher incidence of birth trauma including the maternal genital injuries. Both conditions are associated with higher rates of operative delivery and hence it is important to investigate parameters which could identify these foetal growth abnormalities

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2

Seo, Min-Soo, Kyung-Ku Kang, Se-Kyung Oh, et al. "Isolation and Characterization of Feline Wharton’s Jelly-Derived Mesenchymal Stem Cells." Veterinary Sciences 8, no. 2 (2021): 24. http://dx.doi.org/10.3390/vetsci8020024.

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Wharton’s jelly is a well-known mesenchymal stem cell source in many species, including humans. However, there have been no reports confirming the presence of mesenchymal stem cells in Wharton’s jelly in cats. The purpose of this study was to isolate mesenchymal stem cells (MSCs) from the Wharton’s jelly of cats and to characterize stem cells. In this study, feline Wharton’s jelly-derived mesenchymal stem cells (fWJ-MSCs) were isolated and successfully cultured. fWJ-MSCs were maintained and the proliferative potential was measured by cumulative population doubling level (CPDL) test, scratch te

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3

Gogiel, Tomasz, Edward Bańkowski, and Stefan Jaworski. "Proteoglycans of Wharton’s jelly." International Journal of Biochemistry & Cell Biology 35, no. 10 (2003): 1461–69. http://dx.doi.org/10.1016/s1357-2725(03)00128-6.

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4

Murphy, Sarah J., Nikita Deegan, Bobby D. O'Leary, and Peter McParland. "Absence of Wharton’s jelly." BMJ Case Reports 13, no. 11 (2020): e237222. http://dx.doi.org/10.1136/bcr-2020-237222.

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Wharton’s jelly is a specialised tissue which surrounds the vasculature within the fetal umbilical cord. We present the case of a 42-year-old woman who gave birth to a female infant via emergency caesarean section. At the time of delivery, absence of Wharton’s jelly was noted. This finding was confirmed by histological examination. Emergency caesarean section was necessitated due to a fetal bradycardia, and of note, the patient had presented twice prior to this with reduced fetal movements.

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Dhitiseith, D., and S. Honsawek. "Differential Expression of Osteogenic Differentiation in Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells Treated with Demineralized Bone." Advanced Materials Research 55-57 (August 2008): 697–700. http://dx.doi.org/10.4028/www.scientific.net/amr.55-57.697.

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Mesenchymal stem cells are multipotential cells capable of differentiating into osteoblasts, chondrocytes, adipocytes, tenocytes, and myoblasts. Wharton’s jelly consists of stem cells that are a rich source of primitive multipotent mesenchymal cells. Demineralized bone matrix (DBM) has been widely utilized as a biomaterial to promote new bone formation. We isolate and characterize umbilical cord Wharton’s Jelly-derived mesenchymal stem (UCMS) cells derived from Wharton’s jelly and examine the biological activity of DBM in this cell line. Osteoblast differentiation of the UCMS cells was determi

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Świstowska, Małgorzata, Paulina Gil-Kulik, Arkadiusz Krzyżanowski, et al. "Potential Effect of SOX2 on the Cell Cycle of Wharton’s Jelly Stem Cells (WJSCs)." Oxidative Medicine and Cellular Longevity 2019 (June 2, 2019): 1–8. http://dx.doi.org/10.1155/2019/5084689.

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The connective tissue of the umbilical cord contains stem cells called Wharton’s jelly cells. These cells express core transcription factors (NANOG, OCT4, and SOX2). The protein product of the SOX2 gene controls the cell cycle by interacting with cyclin D (directly and indirectly) and cycle inhibitors—p21 and p27, as well as two E2f3 protein isoforms. The aim of the study was to analyze the effect of SOX2 on the cell cycle of stem cells of Wharton’s jelly. The material for the study was the stem cells of Wharton’s jelly isolated from 20 umbilical cords collected during childbirth. The stem cel

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Rajasekharan, Sreekumar, UmesanKannanvilakom Govindapillai, Manju Madhavan C., Suja R. S., Swapna T, and Sajeena Narayanan Chitradevi. "To Estimate the Importance of Wharton’s Jelly in the Growth of the Foetus – A Light Microscopic Study." Journal of Evolution of Medical and Dental Sciences 10, no. 35 (2021): 3024–29. http://dx.doi.org/10.14260/jemds/2021/617.

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BACKGROUND Human umbilical cord contains two arteries and one vein with their tunica intima and tunica media layers. The role of tunica adventitia is fulfilled by Wharton’s jelly, a mucoid connective tissue. The function of Wharton’s jelly is to prevent the vessels from compression and torsion which is essential for foetal development. The purpose of the study was to estimate the importance of Wharton’s jelly in the growth of the foetus. METHODS Umbilical cord tissue collected from each case was immediately put in 10 % formalin for fixation. Slides were then stained with Haematoxylin and Eosin

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8

Stocco, Elena, Silvia Barbon, Daniele Dalzoppo, et al. "Tailored PVA/ECM Scaffolds for Cartilage Regeneration." BioMed Research International 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/762189.

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Articular cartilage lesions are a particular challenge for regenerative medicine due to cartilage low self-ability repair in case of damage. Hence, a significant goal of musculoskeletal tissue engineering is the development of suitable structures in virtue of their matrix composition and biomechanical properties. The objective of our study was to designin vitroa supporting structure for autologous chondrocyte growth. We realized a biohybrid composite scaffold combining a novel and nonspecific extracellular matrix (ECM), which is decellularized Wharton’s jelly ECM, with the biomechanical proper

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9

Behera, Shashi Shankar, Shashi Shankar Behera, and Prafulla Kumar Chinara. "EVALUATION OF FETAL WEIGHT SONOGRAPHICALLY USING AREA OF WHARTON’S JELLY AND MORPHOLOGY OF UMBILICAL CORD." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 253. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.20037.

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Objective: To establish a sonographic relationship between Area of Wharton’s Jelly (AWJ) and umbilical cord morphometry with the birth weight of the fetus in low-risk pregnancies from 13 to 40 weeks.Methods: A total of 800 singleton pregnant females were subjected for routine sonographic evaluation. The umbilical cord length, diameter, and AWJ were determined. The gestational age and fetal weight were determined using usual fetal parameters. Umbilical cord morphometry along with Area of Wharton Jelly can be utilized as other parameters to increase the accuracy of fetal weight.Results: In our s

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10

Stefańska, Katarzyna, Katarzyna Ożegowska, Greg Hutchings, et al. "Human Wharton’s Jelly—Cellular Specificity, Stemness Potency, Animal Models, and Current Application in Human Clinical Trials." Journal of Clinical Medicine 9, no. 4 (2020): 1102. http://dx.doi.org/10.3390/jcm9041102.

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Stem cell therapies offer a great promise for regenerative and reconstructive medicine, due to their self-renewal and differentiation capacity. Although embryonic stem cells are pluripotent, their utilization involves embryo destruction and is ethically controversial. Therefore, adult tissues that have emerged as an alternative source of stem cells and perinatal tissues, such as the umbilical cord, appear to be particularly attractive. Wharton’s jelly, a gelatinous connective tissue contained in the umbilical cord, is abundant in mesenchymal stem cells (MSCs) that express CD105, CD73, CD90, Oc

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Cole, Jennifer, and Fidan Israfil-Bayli. "Wharton’s jelly: The significance of absence." Journal of Obstetrics and Gynaecology 36, no. 4 (2016): 500–501. http://dx.doi.org/10.3109/01443615.2015.1094041.

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12

Sobolewski, Krzysztof, Edward Bańkowski, Lech Chyczewski, and Stefan Jaworski. "Collagen and Glycosaminoglycans of Wharton’s Jelly." Neonatology 71, no. 1 (1997): 11–21. http://dx.doi.org/10.1159/000244392.

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13

Trivedi, Swati, Lata Ratanoo, Shivani Purohit, and Prasoon Rastogi. "Absence of Wharton’s jelly: an association with feto-maternal morbidity." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 3 (2020): 1318. http://dx.doi.org/10.18203/2320-1770.ijrcog20200926.

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Umbilical cord contains two arteries and one vein connecting fetus to the placenta and is responsible for blood flow between the two. It is surrounded by Wharton’s jelly which is a gelatinous substance and functions as adventitia layer of umbilical vessels, thereby providing insulation and protection to the umbilical cord. Umbilical cord abnormalities are associated with poor perinatal outcomes. Very few cases of absent Wharton’s jelly are reported in literature. Ours might be the 8th one in which we did a lower segment caesarean section for meconium stained liquor but the baby died after 12 h

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14

Sidhom, Elga, Māra Pilmane, and Ilze Kreicberga. "Molecular events in the Wharton’s jelly and blood vessels of human umbilical cord." Papers on Anthropology 26, no. 2 (2017): 113. http://dx.doi.org/10.12697/poa.2017.26.2.12.

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The umbilical cord is seen as the main junction between the developing embryo or fetus and placenta. We studied the antimicrobial response, the presence of undifferentiated cells and TGF-α, as well as tissue degeneration and compensatory remodelling processes in the cells of human umbilical cord.Seven umbilical cord tissue samples obtained during premature and full term births were stained with hematoxylin and eosin and by immunohistochemistry for human beta defensin 2 (hBD-2), hematopoietic progenitor cell antigen CD34, matrix metalloproteinase 2 (MMP-2), the tissue inhibitor of matrix metall

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15

Afroze, Khizer Hussain, Lakshmiprabha Subash, and Anand S. H. "Antenatal sonographic assessment of cross sectional area of umbilical cord components and its reference value in normal pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 10 (2018): 3924. http://dx.doi.org/10.18203/2320-1770.ijrcog20183851.

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Background: Measuring the cross-sectional area of umbilical components in normal pregnant women helps in assessing the fetal abnormalities. Very few literatures were available on evaluation of reference values of cross sectional areas of umbilical cord components. The present study was conducted with the aim to determine the normal reference values of cross sectional areas of umbilical arteries, umbilical vein and Wharton’s jelly and to correlate them with the gestational age of the fetus.Methods: A cross sectional study was conducted on 300 normal pregnant women at the Department of Radiodiag

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Taghizadeh, R. R., K. J. Cetrulo, and C. L. Cetrulo. "Wharton’s Jelly stem cells: Future clinical applications." Placenta 32 (October 2011): S311—S315. http://dx.doi.org/10.1016/j.placenta.2011.06.010.

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Małkowski, Andrzej, Krzysztof Sobolewski, Stefan Jaworski та Edward Bańkowski. "TGF-β binding in human Wharton’s jelly". Molecular and Cellular Biochemistry 311, № 1-2 (2008): 137–43. http://dx.doi.org/10.1007/s11010-008-9704-x.

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18

Tsymbaliuk, V., O. Velychko, O. Pichkur, S. Verbovska, L. Pichkur, and N. Shuvalova. "Effects of human Wharton’s jelly-derived mesenchymal stem cells and Interleukin-10 on behavioural responses of rats with experimental allergic encephalomyelitis." Cell and Organ Transplantology 3, no. 1 (2015): 46–51. http://dx.doi.org/10.22494/cot.v3i1.19.

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On the rat model of experimental allergic encephalomyelitis (EAE), as analogue of multiple sclerosis of human, we studied the effect of Wharton’s jelly-derived mesenchymal stem cells and interleukin-10 on the functional parameters of the CNS.Materials and methods. EAE was induced with spinal cord homogenate of rats with complete Freund’s adjuvant. MSCs were isolated by the explants technique from Wharton’s jelly of the human umbilical cord and cultured up to two passages. Recombinant IL-10 was administered intravenously on the day 10 after induction of EAE and subocipitally on the day 17 at a

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Kulkarni, M. L., Prakash S. Matadh, C. Ashok, N. Pradeep, T. Avinash, and Akhil M. Kulkarni. "Absence of Wharton’s jelly around the umbilical arteries." Indian Journal of Pediatrics 74, no. 8 (2007): 787–89. http://dx.doi.org/10.1007/s12098-007-0142-7.

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20

Jang, Jun Ho, Hyun Woo Lee, Young-Woo Eom, et al. "Usefulness of Wharton’s Jelly, Cord Blood, and Adipose Tissue as Alternative Sources of Mesenchymal Stem Cells." Blood 108, no. 11 (2006): 4250. http://dx.doi.org/10.1182/blood.v108.11.4250.4250.

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Abstract Mesenchymal stem cells (MSCs) are a highly promising source of adult stem cells for purposes of cell therapy and tissue repair in the field of regenerative medicine. Although the most studied and accessible source of MSC is the bone marrow, the clinical use of bone marrow-derived MSCs (BMSCs) has presented problems, including pain, morbidity, and low cell number upon harvest. For those reasons, we isolated, cultured, and characterized MSCs from a number of tissues; including wharton’s jelly, cord blood, and adipose tissues that were discarded routinely in the past, and evaluated the u

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Lina, Yani, and Andi Wijaya. "Novel Sources of Fetal Stem Cells for Future Regenerative Medicine." Indonesian Biomedical Journal 4, no. 1 (2012): 3. http://dx.doi.org/10.18585/inabj.v4i1.155.

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BACKGROUND: Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion of mesenchymal stromal cells derived from bone marrow may be insufficient. Thus, alternative sources of mesenchymal stromal cells need to be explored.CONTENT: There are multiple extra-embryonic tissues emerging during gestation including umbilical cord blood (UCB), amniotic fluid (AF), Wharton’s jelly, the amniotic membrane and the placenta, w

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Gil-Kulik, Paulina, Piotr Chomik, Arkadiusz Krzyżanowski, et al. "Influence of the Type of Delivery, Use of Oxytocin, and Maternal Age on POU5F1 Gene Expression in Stem Cells Derived from Wharton’s Jelly within the Umbilical Cord." Oxidative Medicine and Cellular Longevity 2019 (December 14, 2019): 1–8. http://dx.doi.org/10.1155/2019/1027106.

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The paper presents an evaluation of the POU5F1 gene expression in mesenchymal stem cells derived from Wharton’s jelly within the umbilical cord, collected from 36 patients during labor. The study is the first one to show that the expression of POU5F1 in mesenchymal stem cells has been dependent on maternal age, birth order, route of delivery, and use of oxytocin. Our research proves that the POU5F1 gene expression in mesenchymal stem cells decreases with each subsequent pregnancy and delivery. Wharton’s jelly stem cells obtained from younger women and during their first delivery, as well as pa

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23

Szydlak, Renata, Marcin Majka, Małgorzata Lekka, Marta Kot, and Piotr Laidler. "AFM-based Analysis of Wharton’s Jelly Mesenchymal Stem Cells." International Journal of Molecular Sciences 20, no. 18 (2019): 4351. http://dx.doi.org/10.3390/ijms20184351.

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Wharton’s jelly mesenchymal stem cells (WJ-MSCs) are multipotent stem cells that can be used in regenerative medicine. However, to reach the high therapeutic efficacy of WJ-MSCs, it is necessary to obtain a large amount of MSCs, which requires their extensive in vitro culturing. Numerous studies have shown that in vitro expansion of MSCs can lead to changes in cell behavior; cells lose their ability to proliferate, differentiate and migrate. One of the important measures of cells’ migration potential is their elasticity, determined by atomic force microscopy (AFM) and quantified by Young’s mod

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Gil-Kulik, Paulina, Małgorzata Świstowska, Adrianna Kondracka, et al. "Increased Expression of BIRC2, BIRC3, and BIRC5 from the IAP Family in Mesenchymal Stem Cells of the Umbilical Cord Wharton’s Jelly (WJSC) in Younger Women Giving Birth Naturally." Oxidative Medicine and Cellular Longevity 2020 (April 8, 2020): 1–12. http://dx.doi.org/10.1155/2020/9084730.

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The knowledge of factors affecting the viability as well as proliferation and therapeutic potential of perinatal stem cells is of great importance for the decisions concerning their collection, multiplication, and storing. The aim of this work is to evaluate the expression of the BIRC2, BIRC3, and BIRC5 genes at the level of transcription in mesenchymal stem cells derived from the umbilical cord Wharton’s jelly. The study examined the relationship between the expression level of the studied genes and selected biophysical parameters of umbilical blood: pH, pCO2, pO2, and cHCO3. Moreover, the re

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Yoon, Jong Hyun, Eun Youn Roh, Sue Shin, et al. "Comparison of Explant-Derived and Enzymatic Digestion-Derived MSCs and the Growth Factors from Wharton’s Jelly." BioMed Research International 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/428726.

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Wharton’s jelly is not only one of the most promising tissue sources for mesenchymal stem cells (MSCs) but also a source of natural growth factors. To prove that we can get both natural growth factors and MSCs from Wharton’s jelly, we compared cellular characteristics and the level of basic fibroblast growth factor (bFGF) from samples using the explant culture method to those derived from the traditional enzymatic culture method. The levels of bFGF were27.0±11.7 ng/g on day 3,15.6±11.1 ng/g on day 6, and decreased to2.6±1.2 ng/g on day 14. The total amount of bFGF released was55.0±25.6 ng/g on

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TOKTAROVA, O. A., D. A. ISHMAEVA, and Ya E. HERMAN. "Combined pathology of the umbilical cord as a cause of perinatal losses." Practical medicine 19, no. 2 (2021): 87–91. http://dx.doi.org/10.32000/2072-1757-2021-2-87-91.

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The article presents a clinical case of the antenatal death of a fetus due to a combined umbilical cord pathology prenatally diagnosed with ultrasound: the absence of Wharton’s jelly, thin umbilical cord and the only artery of the umbilical cord. Stages of prenatal care using the methods of visual examination of the fetus are described.

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Hajazimian, Saba, Masoud Maleki, Shahla Danaei Mehrabad, and Alireza Isazadeh. "Human Wharton’s jelly stem cells inhibit endometriosis through apoptosis induction." Reproduction 159, no. 5 (2020): 549–58. http://dx.doi.org/10.1530/rep-19-0597.

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Endometriosis is a relatively benign disease characterized by endometrial tumors and uterus stroma. Apoptosis suppression is one of the most important pathological processes of endometriosis. Recently, several studies reported that human Wharton’s jelly stem cells (hWJSCs) can inhibit growth and proliferation of various cancer cells through induction of apoptosis. Therefore, the aim of the present study was to investigate the effects of hWJSCs conditioned medium (hWJSC-CM) and cell-free lysate (hWJSC-CL) on endometriosis cells in vitro. In the present study, effects of different concentrations

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Romanowicz, Lech, and Edward Bańkowski. "Altered Sphingolipid Composition in Wharton’s Jelly of Pre-Eclamptic Newborns." Pathobiology 77, no. 2 (2010): 78–87. http://dx.doi.org/10.1159/000278289.

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Vieira Paladino, Fernanda, Juliana de Moraes Rodrigues, Aline da Silva, and Anna Carla Goldberg. "The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal Stem/Stromal Cells." Stem Cells International 2019 (June 11, 2019): 1–7. http://dx.doi.org/10.1155/2019/3548917.

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The benefits attributed to mesenchymal stem/stromal cells (MSC) in cell therapy applications are mainly attributed to the secretion of factors, which exhibit immunomodulatory and anti-inflammatory effects and stimulate angiogenesis. Despite the desirable features such as high proliferation levels, multipotency, and immune response regulation, there are important variables that must be considered. Although presenting similar morphological aspects, MSC collected from different tissues can form heterogeneous cellular populations and, therefore, manifest functional differences. Thus, the source of

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Cetrulo, C. "26. Wharton’s Jelly stem cells: Isolation, extraction and preliminary characterization." Biology of Blood and Marrow Transplantation 11, no. 11 (2005): 938. http://dx.doi.org/10.1016/j.bbmt.2005.08.024.

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Merlo, Barbara, Gabriella Teti, Eleonora Mazzotti, et al. "Wharton’s Jelly Derived Mesenchymal Stem Cells: Comparing Human and Horse." Stem Cell Reviews and Reports 14, no. 4 (2018): 574–84. http://dx.doi.org/10.1007/s12015-018-9803-3.

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Vennila, Rosy, Raja Sundari M. Sundaram, Sakthivel Selvaraj, et al. "Effect of Human Platelet Lysate in Differentiation of Wharton’s Jelly Derived Mesenchymal Stem Cells." Endocrine, Metabolic & Immune Disorders - Drug Targets 19, no. 8 (2019): 1177–91. http://dx.doi.org/10.2174/1871530319666190226165910.

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Background: Mesenchymal stem cells (MSCs) are highly preferred in clinical therapy for repair and regeneration of diseased tissues for their multipotent properties. Conventionally, MSCs have been cultured in media supplemented with animal derived serum, however, it is ideal to expand MSCs in media containing supplements of human origin for clinical therapy. Currently, a number of human derived products are being studied as an alternative to animal sources. Amongst these, platelet lysate (PL) has gained interest in the culture of MSCs without affecting their phenotypic property. Objective: In t

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Kim, Young Eun, Se In Sung, Yun Sil Chang, So Yoon Ahn, Dong Kyung Sung, and Won Soon Park. "Thrombin Preconditioning Enhances Therapeutic Efficacy of Human Wharton’s Jelly–Derived Mesenchymal Stem Cells in Severe Neonatal Hypoxic Ischemic Encephalopathy." International Journal of Molecular Sciences 20, no. 10 (2019): 2477. http://dx.doi.org/10.3390/ijms20102477.

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We investigated whether thrombin preconditioning of human Wharton’s jelly–derived mesenchymal stem cells (MSCs) improves paracrine potency and thus the therapeutic efficacy of naïve MSCs against severe hypoxic ischemic encephalopathy (HIE). Thrombin preconditioning significantly enhances the neuroprotective anti-oxidative, anti-apoptotic, and anti-cytotoxic effects of naïve MSCs against oxygen–glucose deprivation (OGD) of cortical neurons in vitro. Severe HIE was induced in vivo using unilateral carotid artery ligation and hypoxia for 2 h and confirmed using brain magnetic resonance imaging (M

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Xiao, Tongguang, Weimin Guo, Mingxue Chen, et al. "Fabrication and In Vitro Study of Tissue-Engineered Cartilage Scaffold Derived from Wharton’s Jelly Extracellular Matrix." BioMed Research International 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/5839071.

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The scaffold is a key element in cartilage tissue engineering. The components of Wharton’s jelly are similar to those of articular cartilage and it also contains some chondrogenic growth factors, such as insulin-like growth factor I and transforming growth factor-β. We fabricated a tissue-engineered cartilage scaffold derived from Wharton’s jelly extracellular matrix (WJECM) and compared it with a scaffold derived from articular cartilage ECM (ACECM) using freeze-drying. The results demonstrated that both WJECM and ACECM scaffolds possessed favorable pore sizes and porosities; moreover, they s

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Liu, Shuyun, Yanhui Jia, Mei Yuan, et al. "Repair of Osteochondral Defects Using Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells in a Rabbit Model." BioMed Research International 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/8760383.

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Umbilical cord Wharton’s jelly-derived mesenchymal stem cell (WJMSC) is a new-found mesenchymal stem cell in recent years with multiple lineage potential. Due to its abundant resources, no damage procurement, and lower immunogenicity than other adult MSCs, WJMSC promises to be a good xenogenous cell candidate for tissue engineering. This in vivo pilot study explored the use of human umbilical cord Wharton’s jelly mesenchymal stem cells (hWJMSCs) containing a tissue engineering construct xenotransplant in rabbits to repair full-thickness cartilage defects in the femoral patellar groove. We obse

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Ariyati, Nora, Kusworini Kusworini, Nurdiana Nurdiana та Yohanes Widodo Wirohadidjojo. "Low Degree Hyaluronic Acid Crosslinking Inducing the Release of TGF-Β1 in Conditioned Medium of Wharton’s Jelly-Derived Stem Cells". Open Access Macedonian Journal of Medical Sciences 7, № 10 (2019): 1572–75. http://dx.doi.org/10.3889/oamjms.2019.307.

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BACKGROUND: Presently, the application of stem cells and their paracrine effect for anti-ageing therapy has commenced. Wharton's jelly-derived stem cell conditioned medium (WJSCs-CM) is renowned for increasing proliferation, migrate ageing skin fibroblasts and increase consumption of extracellular transforming growth factor-β (TGF-β). With more than 85% of frequently used dermal filler procedures are hyaluronic acid fillers (HA), a mixture of both with optimal HA crosslinking degree has not yet been identified. AIM: This study aimed to determine the discrepancies in the results of variou

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Shaikh, Arika. "Development of Defined Culture Conditions for Human Wharton’s Jelly Stem Cells." Arsenal: The Undergraduate Research Journal of Augusta University 3, no. 2 (2020): 40. http://dx.doi.org/10.21633/issn.2380.5064/s.2020.03.02.40.

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Bharathiraja, Chinnapandi, Raman Sukirtha, Muthukalingan Krishnan, and Shanmugam Achiraman. "Interaction of Wharton’s Jelly Derived Fetal Mesenchymal Cells with Tumor Cells." Current Stem Cell Research & Therapy 9, no. 6 (2014): 504–7. http://dx.doi.org/10.2174/1574888x09666140507153248.

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Jaimes-Parra, Boris Damian. "Microscopic evaluation of transdifferentiation of Wharton’s jelly stem cells to urothelium." ACTUALIDAD MEDICA 99, no. 793 (2014): 132–35. http://dx.doi.org/10.15568/am.2014.793.or03.

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Rachakatla, Raja Shekar, and Deryl Troyer. "Wharton’s jelly stromal cells as potential delivery vehicles for cancer therapeutics." Future Oncology 5, no. 8 (2009): 1237–44. http://dx.doi.org/10.2217/fon.09.99.

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Kiran, Hakan, Gurkan Kiran, and Yonca Kanber. "Pseudocyst of the umbilical cord with mucoid degeneration of Wharton’s jelly." European Journal of Obstetrics & Gynecology and Reproductive Biology 111, no. 1 (2003): 91–93. http://dx.doi.org/10.1016/s0301-2115(03)00120-9.

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Liau, L. L., B. H. I. Ruszymah, M. H. Ng, and J. X. Law. "Characteristics and clinical applications of Wharton’s jelly-derived mesenchymal stromal cells." Current Research in Translational Medicine 68, no. 1 (2020): 5–16. http://dx.doi.org/10.1016/j.retram.2019.09.001.

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43

Kamolz, Lars-Peter, Maike Keck, and Cornelia Kasper. "Wharton’s jelly mesenchymal stem cells promote wound healing and tissue regeneration." Stem Cell Research & Therapy 5, no. 3 (2014): 62. http://dx.doi.org/10.1186/scrt451.

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Babaee, Abdolreza, Seyed Noureddin Nematollahi-Mahani, Samereh Dehghani-Soltani, Mohammad Shojaei, and Massood Ezzatabadipour. "Photobiomodulation and gametogenic potential of human Wharton’s jelly-derived mesenchymal cells." Biochemical and Biophysical Research Communications 514, no. 1 (2019): 239–45. http://dx.doi.org/10.1016/j.bbrc.2019.04.059.

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He, Haiping, Tokiko Nagamura-Inoue, Atsuko Takahashi, et al. "Immunosuppressive properties of Wharton’s jelly-derived mesenchymal stromal cells in vitro." International Journal of Hematology 102, no. 3 (2015): 368–78. http://dx.doi.org/10.1007/s12185-015-1844-7.

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Kalyuzhnaya, L. I., V. E. Chernov, A. S. Frumkina, et al. "Fabrication of human Wharton’s jelly extra cellular matrix for tissue engineering." Bulletin of the Russian Military Medical Academy 22, no. 1 (2020): 124–30. http://dx.doi.org/10.17816/brmma25980.

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Abstract:

The development of tissue engineering is based on the use of the extracellular matrix as a construct to which cells migrate and attach for proliferation, differentiation, and long-term functioning. The preparation of the matrix is one of the most important tasks, since it must be non-immunogenic, have optimal mechanical properties, contain cell adhesion molecules and growth factors and degrade at the predicted time. The search for biomaterial for the manufacture of the matrix is limited by a number of circumstances. Tissue-specific for the matrix intravital biomaterial is limited, cadaveric is

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Kassem, Dina H., and Mohamed M. Kamal. "Wharton’s Jelly MSCs: Potential Weapon to Sharpen for Our Battle against DM." Trends in Endocrinology & Metabolism 31, no. 4 (2020): 271–73. http://dx.doi.org/10.1016/j.tem.2020.01.001.

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Talebi, Mehdi, Hojjatollah Nozad Charoudeh, Ali Akbar Movassaghpour Akbari, Behzad Baradaran, and Tohid Kazemi. "Acellular Wharton’s Jelly, Potentials in T-Cell Subtypes Differentiation, Activation and Proliferation." Advanced Pharmaceutical Bulletin 10, no. 4 (2020): 617–22. http://dx.doi.org/10.34172/apb.2020.074.

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Abstract:

Purpose : Because of different potentials of T-cell subtypes in T-cell based cellular immunotherapy approaches such as CAR-T cell therapies; Regarding the high cost of the serum-free specific culture media, having distinct control on T-cell subset activation, expansion and differentiation seem crucial in T-cell expansion step of cell preparation methods. By the way, there was no clear data about the effect of acellular Wharton’s Jelly (AWJ) on T-cells expansion, activation or differentiation status. So, we have launched to study the effect of AWJ on T-cell’s immunobiological properties. Method

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Mallis, Panagiotis, Dimitra Boulari, Panagiota Chachlaki, Catherine Stavropoulos Giokas, and Efstathios Michalopoulos. "Vitrified Wharton’s jelly tissue as a biomaterial for multiple tissue engineering applications." Gynecological Endocrinology 36, no. 2 (2019): 139–42. http://dx.doi.org/10.1080/09513590.2019.1632831.

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Buyl, Karolien, Joery De Kock, Mehdi Najar, et al. "Characterization of hepatic markers in human Wharton’s Jelly-derived mesenchymal stem cells." Toxicology in Vitro 28, no. 1 (2014): 113–19. http://dx.doi.org/10.1016/j.tiv.2013.06.014.

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