Academic literature on the topic 'Whole brain imaging'

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Journal articles on the topic "Whole brain imaging"

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Strack, Rita. "Whole-brain imaging with ExLLSM." Nature Methods 16, no. 3 (2019): 217. http://dx.doi.org/10.1038/s41592-019-0336-8.

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Jiang Tao, 江涛, 龚辉 Gong Hui, 骆清铭 Luo Qingming та 袁菁 Yuan Jing. "全脑显微光学成像". Chinese Journal of Lasers 50, № 3 (2023): 0307101. http://dx.doi.org/10.3788/cjl221247.

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Taranda, Julian, and Sevin Turcan. "3D Whole-Brain Imaging Approaches to Study Brain Tumors." Cancers 13, no. 8 (2021): 1897. http://dx.doi.org/10.3390/cancers13081897.

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Although our understanding of the two-dimensional state of brain tumors has greatly expanded, relatively little is known about their spatial structures. The interactions between tumor cells and the tumor microenvironment (TME) occur in a three-dimensional (3D) space. This volumetric distribution is important for elucidating tumor biology and predicting and monitoring response to therapy. While static 2D imaging modalities have been critical to our understanding of these tumors, studies using 3D imaging modalities are needed to understand how malignant cells co-opt the host brain. Here we summa
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Huang, Raymond Y., and Alexander Lin. "Whole-Brain MR Spectroscopy Imaging of Brain Tumor Metabolites." Radiology 294, no. 3 (2020): 598–99. http://dx.doi.org/10.1148/radiol.2020192607.

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Cherry, Simon R. "Functional whole-brain imaging in behaving rodents." Nature Methods 8, no. 4 (2011): 301–3. http://dx.doi.org/10.1038/nmeth0411-301.

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Vogt, Nina. "Unbiased, whole-brain imaging of neural circuits." Nature Methods 16, no. 2 (2019): 142. http://dx.doi.org/10.1038/s41592-019-0313-2.

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Vogt, Nina. "Chromatic multiphoton imaging of the whole brain." Nature Methods 16, no. 6 (2019): 459. http://dx.doi.org/10.1038/s41592-019-0444-5.

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Sempeles, Susan. "Whole-Brain Mapping Enhanced by Automated Imaging." Journal of Clinical Engineering 37, no. 2 (2012): 36–37. http://dx.doi.org/10.1097/jce.0b013e31824d8e8d.

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Offner, Thomas, Daniela Daume, Lukas Weiss, Thomas Hassenklöver, and Ivan Manzini. "Whole-Brain Calcium Imaging in Larval Xenopus." Cold Spring Harbor Protocols 2020, no. 12 (2020): pdb.prot106815. http://dx.doi.org/10.1101/pdb.prot106815.

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Hall, Håkan, Yasmin Hurd, Stefan Pauli, Christer Halldin, and Göran Sedvall. "Human brain imaging post-mortem - whole hemisphere technologies." International Review of Psychiatry 13, no. 1 (2001): 12–17. http://dx.doi.org/10.1080/09540260020024141.

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Dissertations / Theses on the topic "Whole brain imaging"

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Riemer, F. "Quantitative whole brain sodium (²³Na) imaging." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1469279/.

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In this thesis, the challenges of establishing the very first human in vivo 23Na magnetic resonance imaging in the United Kingdom are presented. A comprehensive framework for quantitative human in vivo studies is established and translated for clinical research imaging. Quantitative measures to obtain the sodium bioscale using external calibrants are discussed and results from a scan re-scan reproducibility study on five healthy volunteers are presented. The protocol was subsequently used in a clinical research study and published by a clinical collaborator in a high impact journal. Improvemen
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Krishnan, Nitya. "Multispectral segmentation of whole brain MRI." Morgantown, W. Va. : [West Virginia University Libraries], 2004. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=3753.

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Thesis (M.S.)--West Virginia University, 2004.<br>Title from document title page. Document formatted into pages; contains vii, 89 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 56-59).
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Li, Jennifer Mengbo. "Identification of an Operant Learning Circuit by Whole Brain Functional Imaging in Larval Zebrafish." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:11032.

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When confronted with changing environments, animals can generally adjust their behavior to optimize reward and minimize punishment. The process of modifying one's behavior based on its consequences is referred to as operant or instrumental learning. Operant learning makes specific demands on the animal. The animal must exhibit some flexibility in its behavior, switching from unsuccessful motor responses to potentially successful ones. The animal must represent the consequence of its actions. Finally, the animal must select the correct response based on its past history of reinforcement. Studie
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Horwood, Linda. "The magnetic resonance imaging-based assessment of whole-brain structural integrity in temporal lobe epilepsy." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=21935.

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In temporal lobe epilepsy (TLE), the most common pathological finding ipsilateral to the seizure focus is sclerosis of the hippocampus. Magnetic resonance imaging (MRI) allows the in vivo assessment of brain abnormalities in TLE patients. This thesis presents the application of advanced MRI post-processing techniques in a cross-sectional study of TLE patients and healthy controls, exploring the pattern of atrophy in TLE. Methods include the automatic segmentation of lobar grey and white matter and limbic (cingulate, thalamus, and insula) structures and the manual segmentation of mesial tempora
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Wang, Xue. "An Integrated Multi-modal Registration Technique for Medical Imaging." FIU Digital Commons, 2017. https://digitalcommons.fiu.edu/etd/3512.

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Registration of medical imaging is essential for aligning in time and space different modalities and hence consolidating their strengths for enhanced diagnosis and for the effective planning of treatment or therapeutic interventions. The primary objective of this study is to develop an integrated registration method that is effective for registering both brain and whole-body images. We seek in the proposed method to combine in one setting the excellent registration results that FMRIB Software Library (FSL) produces with brain images and the excellent results of Statistical Parametric Mapping (
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Stevner, Angus Bror Andersen. "Whole-brain spatiotemporal characteristics of functional connectivity in transitions between wakefulness and sleep." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:3ef218c0-a734-4d6f-abf8-ffdb780525aa.

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This thesis provides a novel dynamic large-scale network perspective on brain activity of human sleep based on the analysis of unique human neuroimaging data. Specifically, I provide new information based on integrating spatial and temporal aspects of brain activity both in the transitions between and during wakefulness and various stages of non-rapid-eye movement (NREM) sleep. This is achieved through investigations of inter-regional interactions, functional connectivity (FC), between activity timecourses throughout the brain. Overall, the presented findings provide new important whole-brain
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Curtis, James. "Whole Brain Isotropic Arterial Spin Labeling Magnetic Resonance Imaging in a transgenic mouse model of Alzheimer's Disease." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32516.

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This thesis presents the design, implementation, and validation of a novel, arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI) pulse sequence to generate three-dimensional quantitative maps of cerebral blood flow (CBF) in mice at 7 Tesla with an isotropic 281μm resolution. ASL and anatomical scans were registered to a common template using an automated non-linear registration pipeline to allow for voxel-wise inter-scan and inter-subject comparisons of CBF. The technique was applied to
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Dragomir, Elena I. [Verfasser], and Ruben [Akademischer Betreuer] Portugues. "Perceptual decision making in larval zebrafish revealed by whole-brain imaging / Elena I. Dragomir ; Betreuer: Ruben Portugues." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1214593232/34.

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Ireland, Kirsty Anne. "Development of whole brain organotypic slice culture to investigate in vitro seeding of amyloid plaques." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28707.

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A feature of prion disease and other protein misfolding neurodegenerative disease is the formation of amyloid plaques. Amyloid is commonly found in the brain of individuals who have died from prion disease and Alzheimer’s disease. The formation and purpose of amyloid in such diseases is poorly understood and it is not currently known whether the material is neurotoxic, neuroprotective or an artefact. Several methods are used to investigate the formation of amyloid both in vitro and in vivo. A cell free protein conversion assay has been optimised to gain insight into the protein misfolding path
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Wolf, Sébastien. "The neural substrate of goal-directed locomotion in zebrafish and whole-brain functional imaging with two-photon light-sheet microscopy." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066468/document.

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La première partie de cette thèse présente une revue historique sur les méthodes d'enregistrements d'activité neuronale, suivie par une étude sur une nouvelle technique d'imagerie pour le poisson zèbre : la microscopie par nappe laser 2 photon. En combinant, les avantages de la microscopie 2 photon et l'imagerie par nappe de lumière, le microscope par nappe laser 2 photon garantie des enregistrements à haute vitesse avec un faible taux de lésions photoniques et permet d'éviter l'une des principales limitations du microscope à nappe laser 1 photon: la perturbation du système visuel. La deuxième
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Books on the topic "Whole brain imaging"

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Cohen-Inbar, Or, Daniel M. Trifiletti, and Jason P. Sheehan. Stereotatic Radiosurgery and Microsurgery for Brain Metastases. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190696696.003.0024.

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This chapter describes the case of a patient with brain metastases due to metastatic breast cancer. MRI is the best imaging modality for visualizing brain metastases, and advanced techniques such as perfusion imaging and diffusion weighted imaging may provide important additional information beyond standard anatomic imaging. Patients with brain metastases due to systemic cancer may benefit from targeted therapies such as surgery and stereotactic radiosurgery. Understanding the differences between radiation modalities such as stereotactic radiosurgery and whole brain radiotherapy is important f
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Boedhoe, Premika S. W., and Odile A. van den Heuvel. The Structure of the OCD Brain. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0023.

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This chapter summarizes the most consistent findings of structural neuroimaging studies of obsessive-compulsive disorder (OCD), and discusses their relationship within the implicated brain networks. The techniques used in these studies are diverse, and include manual tracing of specific regions of interest, whole-brain voxel-based morphometry (VBM) for both gray matter and white matter volume comparisons, FreeSurfer to investigate differences in cortical thickness and subcortical volumes, and other methods such as covariance analyses. Findings on white matter integrity with tract-based spatial
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Hillmer, Ansel T., Kelly P. Cosgrove, and Richard E. Carson. PET Brain Imaging Methodologies. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0009.

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While quantitative and pharmacologically specific aspects distinguish molecular imaging, they also impose the need for considerable expertise to design, conduct, and analyze molecular imaging studies. Positron emission tomography (PET) brain imaging provides a powerful noninvasive tool for quantitative and pharmacologically specific clinical research. This chapter describes basic methodological considerations for PET brain imaging studies. First the physiological interpretation of the most common outcome measures of binding potential (BPND) and volume of distribution (VT) are described. Next,
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Gattringer, Thomas, Christian Enzinger, Stefan Ropele, and Franz Fazekas. Brain imaging (CT/MRI). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198722366.003.0007.

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In the acute phase of a suspected stroke, timely brain imaging with rapid and qualified interpretation is a crucial diagnostic step to inform patient management. While brain computed tomography is usually sufficient to indicate thrombolysis within the approved time window (by rapidly excluding intracranial haemorrhage), it often fails to show the actual site and extent of infarction as well as other pathologies, which may mimic a stroke. Magnetic resonance imaging (MRI) has a much higher sensitivity and specificity for ischaemic vascular brain changes and thus allows direct demonstration of th
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Seeck, Margitta, L. Spinelli, Jean Gotman, and Fernando H. Lopes da Silva. Combination of Brain Functional Imaging Techniques. Edited by Donald L. Schomer and Fernando H. Lopes da Silva. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228484.003.0046.

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Several tools are available to map brain electrical activity. Clinical applications focus on epileptic activity, although electric source imaging (ESI) and electroencephalography-coupled functional magnetic resonance imaging (EEG–fMRI) are also used to investigate non-epileptic processes in healthy subjects. While positron-emission tomography (PET) reflects glucose metabolism, strongly linked with synaptic activity, and single-photon-emission computed tomography (SPECT) reflects blood flow, fMRI (BOLD) signals have a hemodynamic component that is a surrogate signal of neuronal (synaptic) activ
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Thompson, Evan. Looping Effects and the Cognitive Science of Mindfulness Meditation. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190495794.003.0003.

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Cognitive neuroscience tends to conceptualize mindfulness meditation as inner observation of a private mental realm of thoughts, feelings, and body sensations, and tries to model mindfulness as instantiated in neural networks visible through brain imaging tools such as EEG and fMRI. This approach confuses the biological conditions for mindfulness with mindfulness itself, which, as classically described, consists in the integrated exercise of a whole host of cognitive and bodily skills in situated and ethically directed action. From an enactive perspective, mindfulness depends on internalized s
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Brennan, Brian P., and Scott L. Rauch. Functional Neuroimaging Studies in Obsessive-Compulsive Disorder: Overview and Synthesis. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0021.

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Studies using functional neuroimaging have played a critical role in the current understanding of the neurobiology of obsessive-compulsive disorder (OCD). Early studies using positron emission tomography (PET) identified a core cortico-striatal-thalamo-cortical circuit that is dysfunctional in OCD. Subsequent studies using behavioral paradigms in conjunction with functional magnetic resonance imaging (fMRI) have provided additional information about the neural substrates underlying specific psychological processes relevant to OCD. More recently, studies utilizing resting state fMRI have identi
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Kleege, Georgina. Touching on Science. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190604356.003.0003.

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While the Hypothetical Blind man is a useful prop for philosophical theories of mind, he also influences the research of many contemporary neuroscientists. This chapter will survey cases of “restored sight” from the eighteenth century to the present. These cases follow such a predictable script that they have supplied the plots of such literary texts as Wilke Collins’s Poor Miss Finch and Brian Friel’s Molly Sweeney. The chapter will go on to describe research on brain plasticity that employs blind subjects to investigate various aspects of tactile perception and mental imaging, without any di
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Hoftman, Gil D., and Dean F. Salisbury. Neurobiology of Schizophrenia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199331505.003.0005.

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Schizophrenia is a brain disease with unknown etiology; a variety of neurodevelopmental mechanisms contribute to its pathogenesis. In this chapter, we review some of the most salient neurobiological findings that seem to be linked with the pathophysiology of psychosis generally and schizophrenia specifically. Several important findings have been made from neuroimaging and neuropathology, including reduced whole-brain volume, enlarged ventricles, and decreased cortical gray matter. Abnormalities in the prefrontal cortex, such as decreased dendritic spine density, are particularly important for
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Rubia, Katya. ADHD brain function. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198739258.003.0007.

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ADHD patients appear to have complex multisystem impairments in several cognitive-domain dissociated inferior, dorsolateral, and medial fronto-striato-parietal and frontocerebellar neural networks during inhibition, attention, working memory, and timing functions. There is emerging evidence for abnormalities in motivation and affect control regions, most prominently in ventral striatum, but also orbital/ventromedial frontolimbic areas. Furthermore, there is an immature interrelationship between hypoengaged task-positive cognitive control networks and a poorly ‘switched off’ default mode networ
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Book chapters on the topic "Whole brain imaging"

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Pawłowska, Monika, Marzena Stefaniuk, Diana Legutko, and Leszek Kaczmarek. "Light-Sheet Microscopy for Whole-Brain Imaging." In Advanced Optical Methods for Brain Imaging. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-9020-2_3.

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Carass, Aaron, Muhan Shao, Xiang Li, et al. "Whole Brain Parcellation with Pathology: Validation on Ventriculomegaly Patients." In Patch-Based Techniques in Medical Imaging. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67434-6_3.

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Zhou, Shuo, Christopher R. Cox, and Haiping Lu. "Improving Whole-Brain Neural Decoding of fMRI with Domain Adaptation." In Machine Learning in Medical Imaging. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-32692-0_31.

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Muto, Mario, and Alessandra D’Amico. "Radiation-Induced Leukoencephalopathy: MR Follow-Up After Whole Brain Radiation Therapy." In Imaging Gliomas After Treatment. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-31210-7_55.

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Ren, Jian, and Brett E. Bouma. "Whole Murine Brain Imaging Based on Optical Elastic Scattering." In Advances in Experimental Medicine and Biology. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-7627-0_6.

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Zhao, Can, Aaron Carass, Junghoon Lee, Yufan He, and Jerry L. Prince. "Whole Brain Segmentation and Labeling from CT Using Synthetic MR Images." In Machine Learning in Medical Imaging. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67389-9_34.

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Kist, Andreas M., Laura D. Knogler, Daniil A. Markov, Tugce Yildizoglu, and Ruben Portugues. "Whole-Brain Imaging Using Genetically Encoded Activity Sensors in Vertebrates." In Decoding Neural Circuit Structure and Function. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-57363-2_13.

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Schenck, J. F., O. M. Mueller, S. P. Souza, and C. L. Dumoulin. "Magnetic Resonance Imaging of Brain Iron Using A4 Tesla Whole-Body Scanner." In Iron Biominerals. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3810-3_27.

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Yan, Zhennan, Shaoting Zhang, Xiaofeng Liu, Dimitris N. Metaxas, and Albert Montillo. "Accurate Whole-Brain Segmentation for Alzheimer’s Disease Combining an Adaptive Statistical Atlas and Multi-atlas." In Medical Computer Vision. Large Data in Medical Imaging. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05530-5_7.

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Yan, Zhennan, Shaoting Zhang, Xiaofeng Liu, Dimitris N. Metaxas, and Albert Montillo. "Accurate Whole-Brain Segmentation for Alzheimer’s Disease Combining an Adaptive Statistical Atlas and Multi-atlas." In Medical Computer Vision. Large Data in Medical Imaging. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-14104-6_7.

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Conference papers on the topic "Whole brain imaging"

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Chang, Heng, Zhi-Yuan Chang, Kai-Chun Jhan, et al. "Digital scanning lightsheet microscopy (DSLM) for Drosophila whole brain functional imaging." In Neural Imaging and Sensing 2025, edited by Qingming Luo, Jun Ding, and Ling Fu. SPIE, 2025. https://doi.org/10.1117/12.3041113.

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Pang, Weiran, Liming Nie, and Puxiang Lai. "Voltage-sensitive dye-based photoacoustic imaging visualization of whole brain electrodynamics." In Photons Plus Ultrasound: Imaging and Sensing 2025, edited by Alexander A. Oraevsky and Lihong V. Wang. SPIE, 2025. https://doi.org/10.1117/12.3040468.

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Li, Yuxin, Weijie He, Jia Cao, Anan Li, Xiangning Li, and Tao Jiang. "Mapping the density distribution pattern of microvasculature in whole-mouse brain." In Seventeenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2024), edited by Valery V. Tuchin, Qingming Luo, and Lihong V. Wang. SPIE, 2025. https://doi.org/10.1117/12.3057558.

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Gros, Romane, Omar Rodríguez-Núñez, Stefano Moriconi, et al. "Whole-brain section image reconstruction for deciphering tumor margin using Mueller polarimetry imaging." In Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2025, edited by Jessica C. Ramella-Roman, Hui Ma, I. Alex Vitkin, Daniel S. Elson, and Tatiana Novikova. SPIE, 2025. https://doi.org/10.1117/12.3042903.

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Zhao, Jiaying, Yongquan Ye, Jing Cheng, et al. "Accelerating the Whole-Brain Multi-Parametric Imaging Through Joint Deep Learning Reconstruction and Physical Model Integration." In 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI). IEEE, 2025. https://doi.org/10.1109/isbi60581.2025.10981305.

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Noun, Abir, Racha Soubra, and Aly Chkeir. "Beyond the Striatum: A Whole-Brain Approach for Parkinson's Disease Diagnosis Using 3D CNNs and DaTSCAN SPECT Imaging." In 2025 IEEE Medical Measurements & Applications (MeMeA). IEEE, 2025. https://doi.org/10.1109/memea65319.2025.11067983.

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Silvestri, Ludovico, Anna Letizia Allegra Mascaro, Irene Costantini, Leonardo Sacconi, and Francesco S. Pavone. "Whole brain optical imaging." In SPIE BiOS, edited by Henry Hirschberg, Steen J. Madsen, E. Duco Jansen, Qingming Luo, Samarendra K. Mohanty, and Nitish V. Thakor. SPIE, 2015. http://dx.doi.org/10.1117/12.2087339.

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Ueda, Hiroki R. "Whole-body and whole-organ clearing and imaging with single-cell resolution." In Optics and the Brain. OSA, 2017. http://dx.doi.org/10.1364/brain.2017.brw2b.2.

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Umadevi Venkataraju, Kannan U., James Gornet, Gayathri Murugaiyan, Zhuhao Wu, and Pavel Osten. "Development of brain templates for whole brain atlases." In Neural Imaging and Sensing 2019, edited by Qingming Luo, Jun Ding, and Ling Fu. SPIE, 2019. http://dx.doi.org/10.1117/12.2505295.

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Menzel, Miriam, Marouan Ritzkowski, David Grässel, Philipp Schlömer, Katrin Amunts, and Markus Axer. "Scatterometry on whole brain sections using Scattered Light Imaging." In Optics and the Brain. OSA, 2021. http://dx.doi.org/10.1364/brain.2021.btu1b.2.

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Reports on the topic "Whole brain imaging"

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Brody, David L. Radiological-Pathological Correlations Following Blast-Related Traumatic Brain Injury in the Whole Human Brain Using ex Vivo Diffusion Tensor Imaging. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada597888.

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MR (Diffusion-Weighted Imaging (DWI) of the Apparent Diffusion Coefficient (ADC), Clinically Feasible Profile. Chair Michael Boss, Dariya Malyarenko, and Daniel Margolis. Radiological Society of North America (RSNA) / Quantitative Imaging Biomarkers Alliance (QIBA), 2022. http://dx.doi.org/10.1148/qiba/20221215.

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The goal of a QIBA Profile is to help achieve a useful level of performance for a given biomarker. The Claim (Section 2) describes the biomarker performance and is derived from the body of scientific literature meeting specific requirements, in particular test-retest studies. The Activities (Section 3) contribute to generating the biomarker. Requirements are placed on the Actors that participate in those activities as necessary to achieve the Claim. Assessment Procedures (Section 4) for evaluating specific requirements are defined as needed to ensure acceptable performance. Diffusion-Weighted
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