Relevant bibliographies by topics / Whooping Cough, therapy

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  2. Dissertations / Theses
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Academic literature on the topic 'Whooping Cough, therapy'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 January 2023

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Journal articles on the topic "Whooping Cough, therapy"

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Ivanchenko, N. "Pertussis treatment strategies." Bukovinian Medical Herald 25, no. 2(98) (August 26, 2021): 135–40. http://dx.doi.org/10.24061/2413-0737.xxv.2.98.2021.22.

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Whooping cough, despite the fact that the disease has long been known, still remains a problem for all countries. Cough attacks can cause not only physical discomfort to the patient, but also a significant negative psycho-emotional load. Existing drug therapy to date does not solve all the problems in the treatment of whooping cough. The aim of our study was to conduct a literature review of pertussis treatment and evaluate the efficacy of inhaled corticosteroids in adult patients with moderate to severe disease.Material and methods. Guidelines for the treatment of whooping cough were studied, and 26 medical records of inpatients with the diagnosis of “Pertussis” were analysed. Conclusion. Antibiotic therapy is a mandatory component of treatment. The effectiveness of inhaled corticosteroids in adult patients with moderate to severe whooping cough has been established.
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Stojanovic, Vesna, Nenad Barisic, Aleksandra Doronjski, Dorottya Csuka, and Zoltán Prohászka. "Hemolytic uremic syndrome complicating whooping cough." Srpski arhiv za celokupno lekarstvo 147, no. 1-2 (2019): 89–93. http://dx.doi.org/10.2298/sarh171207058s.

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Introduction. We shall present a case of a two-month old infant who has developed a haemolytic uremic syndrome as an atypical complication of Bordetella pertussis infection. The observation that the development of haemolytic uremic syndrome is a late complication of Bordetella pertussis infection may be a clue for further studies. Case outline. A two-month-old female infant was admitted to the hospital because of fever, intensive cough, shortness of breath and poor feeding. Real-time polymerase chain reaction (PCR) for Bordetella pertussis was positive. A macrolide was introduced in therapy. On the eighth hospital day, the infant?s condition improved, she became afebrile and eupneic. On the 16th hospital day, she developed signs of progressive respiratory distress and oliguric acute kidney injury. Hemolytic uremic syndrome (HUS) was diagnosed, so the therapy with the fresh frozen plasma (FFP) transfusion, therapeutic plasma exchange and peritoneal dialysis was initiated. Levels of ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) were decreased, while the levels of factor H, factor B, and factor I were normal. Despite the full supportive and targeted care, severe multiple organ failure had developed and on the 24th hospital day the infant died. Conclusion. Further studies are necessary to identify the mechanism of potential interaction between pertussis toxins, pathophysiology of the infection and the interaction of complement activation, coagulation and the regulation of these cascades.
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Zvereva, N. N., and M. A. Saifullin. "Features of antitussive therapy in whooping cough in pediatric practice." Meditsinskiy sovet = Medical Council, no. 18 (November 28, 2020): 42–47. http://dx.doi.org/10.21518/2079-701x-2020-18-42-47.

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Pimenova, A. S., O. Yu Borisova, M. S. Petrova, I. S. Voronina, A. B. Borisova, O. V. Shamsheva, S. S. Afanasiev, E. V. Vlasov, and V. A. Aleshkin. "EFFICIENCY OF APPLICATION OF ISOTHERMAL AMPLIFICATION AT INSPECTION OF PATIENTS WITH WHOOPING COUGH." Russian Journal of Infection and Immunity 8, no. 3 (November 4, 2018): 361–68. http://dx.doi.org/10.15789/2220-7619-2018-3-361-368.

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Purpose: efficiency isothermal amplification (LAMP) at inspection of patients with whooping cough in clinical conditions. Materials and methods. Examination of 262 patients aged from 0 months up to 30 years hospitalized in Infectious diseases clinical hospital No. 1 of the Moscow Department of Healthcare is conducted. Clinical specimens (pharyngeal swabs) were collected according to MR 3.1.2.0072-13. Extraction DNA of B. pertussiswas carried out by means of the АmplyPrime® DNA-sorb-AM. Identification of specific fragments of a genome of B. pertussiswas performed by PCR-real time by means of the АmplySens ® Bordetella Multi-FL set (a comparison method) and by the LAMP with a phoresis and intercalating dye. Results.When using of the optimized method LAMP the DNA of B. pertussisis found at 252 (96.2%) patients. The method was effective at any forms of whooping cough —DNA of B. pertussisis found in all patients with a severe form, in 95.8% of cases — in patients with medium-weight and in 95.3% of cases — in patients with an easy form. The DNA of B. pertussisis found in clinical specimens received from patients on different terms from the beginning of a disease — from 92.3% on the 1st week up to 96% of cases — on the 5 th and more weeks of a disease. The DNA of B. pertussisis found in high percent of cases (96.7–95.9%) and did not depend on acceptance of antibacterial therapy. Children till 1 year are the main age group which is subject to hospitalization at suspicion of whooping cough and in which the highest risk of development of complications and severe forms of a clinical disease. At inspection of 169 children from 0 to 12 months by means of the optimized method LAMP, DNA of B. pertussisit is found in 98.6% of cases in children of patients with whooping cough aged from 0–3 months, in 98.4% of cases — children of 4–7 months and in 94.6% of cases — at children have 8–12 months. The efficiency of detection of DNA of B. pertussisat patients with whooping cough of children aged till 1 year by means of the optimized LAMP method was 97.6%.
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Orlova, N. V. "Chronic cough: differential diagnosis and treatment." Meditsinskiy sovet = Medical Council, no. 17 (November 22, 2020): 124–31. http://dx.doi.org/10.21518/2079-701x-2020-17-124-131.

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Cough is one of the most common symptoms and is present in diseases of the respiratory, cardiovascular, digestive, endocrine and other systems. Cough is a reflex act, therefore it is caused by stimulation of cough receptors due to pathological influences. The diagnosis takes into account the nature of the cough, its duration, the results of laboratory and instrumental examination methods. The most attention is required to diagnose chronic cough and exclude life-threatening causes. Symptoms of anxiety are hemoptysis, prolonged resistant cough, prolonged intoxication syndrome, weight loss, etc. In diagnostically unclear cases, the examination schedule must include computed tomography of the chest, magnetic resonance imaging and bronchoscopy. A dry, painful intense cough can lead to the development of complications: a decrease in the quality of life, hemorrhages, pneumothorax, etc., therefore, requires symptomatic treatment. A common cause of unproductive cough is viral diseases, whooping cough, diseases leading to overactive cough receptors. The variety of coughs determines a differentiated approach to its therapy. The main efforts should be directed to the treatment of the underlying disease. In the case of a productive cough, mucoactive drugs are used. To stop unproductive cough, antitussive drugs of central and peripheral action are used. The recommendations of the European Respiratory Society present the results of clinical trials assessing the efficacy and safety of antitussive drugs with morphine-like action. The study identified side effects that limit their use. One of the most effective and safe drugs is a non-opioid drug with a central action Sinekod. The effectiveness and safety of the drug is confirmed by clinical studies.
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Chernova, T. M., V. N. Timchenko, A. I. Pedash, M. D. Subbotina, O. I. Bulina, E. O. Ermakova, and S. Yu Uskova. "Assessment of the timeliness of vaccination against pertussis in children of the first year of life and the reasons for the violation of the vaccination schedule." Journal Infectology 13, no. 2 (July 14, 2021): 79–86. http://dx.doi.org/10.22625/2072-6732-2021-13-2-79-86.

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The maximum incidence of pertussis in young children confirms the importance of their timely immunization.The goal is – to study the timeliness of vaccination against whooping cough, causes of violation of the vaccination schedule in young children, the effect of recombinant interferon-a on the post-vaccination period.Materials and methods: the vaccination history and data on the course of the post-vaccination period after immunization with DPT and DaPT vaccines of 469 children at the age of 3–24 months were studied.Results. The analysis showed that 14,9% of the observed children were not vaccinated against whooping cough in a timely manner. Of these: 34,3% had a written refusal to vaccinate (5.1% of the total number of observed children), in 32,8% of cases, the vaccination schedule was violated due to late arrival of parents, 32,9% of children by the start of immunization had medical challenges, and only half of them had justified contraindications. Non-serious side effects associated with immunization were observed in 11.3% of cases, statistically more often with DTP (22,0%) compared with DaPT (5.,5%). General and local reactions, in general, were recorded on DPT (6,9% and 15,1%, respectively) and less often developed with the use of DaPT (1,0% and 4,5%, respectively). Within 1 month after immunization, 16,2% of the observed children had an acute respiratory viral infection of varying severity. Those who did not receive antiviral therapy more often carried the disease in a moderate and severe form, which in all cases led to the postponement of the administration of the second and third doses of the vaccine.Conclusion. To increase the timeliness of vaccination of children against whooping cough, medical professionals should persistently remind parents about the timing of turnout for the next vaccination, when making medical withdrawals, be guided by modern methodological documents and instructions for vaccines. The use of antiviral and immunomodulatory effects of IFN-alpha drugs allows us to comply with the recommended schedule for vaccination of children with a high risk of SARS in the post-vaccination period.
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7

Izadi, Morteza, Shahla Afsharpaiman, Nematollah Jonaidi Jafari, Reza Ranjbar, Mohammad Mahdi Gooya, Javad Robat Sarpooshi, Ali Akbar Esfahani, and Hamid Soheylipoor. "Immunization status of Iranian military recruits against Bordetella pertussis infection (whooping cough)." Journal of Infection in Developing Countries 5, no. 03 (March 21, 2011): 224–26. http://dx.doi.org/10.3855/jidc.948.

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Introduction: Military recruits are susceptible to respiratory pathogens because of increased antibiotic resistance and the lack of an effective vaccine. The goal of the current study was to determine the immunological status of the Bordetella pertussis among conscripts in Iranian military garrisons. Methodology: The study population consisted of 424 conscripts aged 18 to 21 years who enrolled for military service. They were selected using cluster stratified sampling from all military garrisons in Tehra, Iran. To determine the seroprevalence of infection, blood specimens from all recruits were collected and stored at - 20°C until assayed. All serum samples were screened for immunoglobulin G (IgG) antibodies against Bordetella pertussis toxin (PT) and by using enzyme-linked immunosorbent assay (ELISA). Results: The overall prevalence of B. pertussis seropositivity in military recruits was 60.6. Only 55.0% of the recruits had low awareness about the record of vaccination against B. pertussis during childhood. Among 424 studied individuals, 48 recruits (11.3%) had a positive history of whooping cough; prevalence of seropositivity in these recruits was 70.0%. Among these subjects, 61.7% were referred to a physician for treatment and only 39.6% of them were administered anti-pertussis therapy. Conclusions: Our study showed that military conscripts in Tehran garrisons were not serologically immune to pertussis and also confirmed the low awareness about vaccination and medical history related to pertussis infection in this high-risk subgroup of the Iranian population. Routine acellular booster vaccination, particularly before 18 years of age, is recommended.
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8

Lees, R. E. M. "Epidemic Disease in Glasgow during the 19th Century." Scottish Medical Journal 41, no. 1 (February 1996): 24–27. http://dx.doi.org/10.1177/003693309604100110.

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19th century Glasgow was an overcrowded city containing some of the worst housing conditions in the UK. Conditions were ripe for epidemics of infectious diseases and they came in waves causing high mortality particularly among the young. Diagnostic difficulties and ineffective therapy meant that little impact was made on these diseases during the first half of the period. Smallpox was the exception — Vaccination of children reduced the incidence and mortality early in the century but subsequent public complacency caused it to return within a few years. Measles and whooping cough surpassed smallpox as the major causes of infectious disease mortality as early as 1810. Epidemics were less common after the three-quarter century mark due to improved living conditions for the poor but also as a result of the assiduous application of Public Health principles.
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9

Kuci, Saimir, Alfred Ibrahimi, Shaban Memeti, Stavri Llazo, Ervin Bejko, Klodian Krakulli, and Edvin Prifti. "Perioperative Evaluation of Heart Echinococcus Cyst in a 14-Year-Old Child." Open Access Macedonian Journal of Medical Sciences 9, no. C (January 20, 2021): 20–24. http://dx.doi.org/10.3889/oamjms.2021.5533.

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BACKGROUND: Echinococcosis of the heart has a rate 0.02–2% of all hydatid diseases. Clinical presentation is depending of the location of hydatid cyst in the heart. Patients can be an asymptomatic case or lethal stroke, arrhythmias, valvular dysfunction, pulmonary edema, cardiac tamponade, cardiac failure, shock, and even death. CASE REPORT: We present a case report, a 14-year-old child with 2 weeks of sore throat, whooping cough, subfebrile condition, sweating, fatigue and physical weakness, nausea, abdominal pain, and decreased appetite. He came to emergency room with cardiogenic shock and pulmonary edema. He was diagnosed with intramyocardial hydatid cyst. CONCLUSION: Echinococcus cyst lesion in the LV in lateral wall, not communicating with the LV cavity, has been removed successfully with on-pump technique in a 14-year-oldchild. Median sternotomy was preferred and cardiopulmonary bypass has been considered the safest method. Supplemental medical therapy with albendazole is recommended to reduce the risk of recurrence.
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10

Calabrese, Edward J., Gaurav Dhawan, and Rachna Kapoor. "Radiotherapy for Pertussis: An Historical Assessment." Dose-Response 15, no. 2 (May 8, 2017): 155932581770476. http://dx.doi.org/10.1177/1559325817704760.

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X-ray therapy was used to treat pertussis/whooping cough during a 13-year period from 1923 to 1936 in North America and Europe. Twenty studies from clinicians in the United States reported that approximately 1500 cases of pertussis were treated by X-ray therapy usually with less than 0.5 erythema dose. Young children (<3 years) comprised about 70% to 80% of the cases, with the age of cases ranging from as young as 1 month to 50 years. In general, symptoms of severe coughing, vomiting episodes, and spasms were significantly relieved in about 85% of cases following up to 3 treatments, while about 15% of the cases showed nearly full relief after only 1 treatment. The X-ray therapy was also associated with a marked reduction in mortality of young (<3 years) children by over 90%. Despite such reported clinical success from a wide range of experienced researchers, the use of X-rays for the treatment of pertussis in young children was controversial, principally due to concerns of exposure to the thymus and thyroid even with the availability of lead shielding. By the mid-1930s, the treatment of pertussis cases via vaccine therapy came to dominate the therapeutic arena, and the brief era of a radiotherapy option for the treatment of pertussis ended.
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Dissertations / Theses on the topic "Whooping Cough, therapy"

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Warren, Andrew Eugene. "The use of inhaled beclomethasone to decrease the duration of paroxysmal coughing in pediatric patients with pertussis : results and methodologic issues in a randomized clinical trial /." St. John's, NF : [s.n.], 1997.

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Books on the topic "Whooping Cough, therapy"

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Kokuritsu Yobō Eisei Kenkyūjo (Japan) and International Association of Biological Standardization., eds. International Symposium on Pertussis, Evaluation, and Research on Acellular Pertussis Vaccines: Proceedings of a symposium supported by the National Institute of Health, Tokyo, and the International Association of Biological Standardization : held at the Teijin Institute of Education and Training, Shizuoka, Japan, September 14-15, 1990. Basel: Karger, 1991.

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2

Tiru, M., Y. Sato, and H. Sato. Pertussis: Evaluation and Research on Acellular Pertussis Vaccines : Proceedings (Developments in Biologicals). S. Karger Publishers (USA), 1991.

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Book chapters on the topic "Whooping Cough, therapy"

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"Pertussis (Whooping Cough)." In The APRN and PA’s Complete Guide to Prescribing Drug Therapy. New York, NY: Springer Publishing Company, 2019. http://dx.doi.org/10.1891/9780826179340.0292.

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"Pertussis (Whooping Cough)." In The APRN and PA’s Complete Guide to Prescribing Drug Therapy. New York, NY: Springer Publishing Company, 2019. http://dx.doi.org/10.1891/9780826179357.0292.

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Daly, Blánaid, Paul Batchelor, Elizabeth Treasure, and Richard Watt. "Evidence-based practice." In Essential Dental Public Health. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199679379.003.0012.

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In the last 40 years, the needs of and demands for health care both in the UK and worldwide have increased dramatically. These increases are related to the population ageing, the development of new technologies and knowledge, rising patient expectations, and associated increases in professional expectations about the possibilities and potential of health care (Muir Gray 1997 ). In this period, the key policy concerns of the international health care community have been about containing costs and enabling equitable access to high quality health care, while also ensuring greater accountability, patient satisfaction, and improved public health (Lohr et al. 1998). Health care resources are finite and must be shared equitably on the basis of need, capacity to benefit, and effectiveness. The use of high quality research evidence and guidelines to inform individual patient care and population health care have become central to this process. In the mid-1970s, various writers began to question the effectiveness of medicine and the increasingly wider influence exerted by the medical profession on society. For example, McKeown (1976) mapped mortality rates for the main killer airborne diseases (tuberculosis, whooping cough, scarlet fever, diptheria, and smallpox) against contemporary advances in medicine from the mid-19th century to the early 1970s. He found that the declines in the incidence and prevalence of communicable diseases had occurred before their microbial cause had been identified and before an effective clinical intervention had been developed. McKeown concluded that the declines in mortality rates were not attributable to immunization and therapy and suggested the declines could more reasonably be attributed to better nutrition and improved housing conditions which had occurred over the period. Allied to McKeown’s historical analysis was the work of Archie Cochrane who evaluated contemporary clinical practice in the 1970s. In his seminal work Effectiveness and Efficiency , Cochrane (1972) showed that many medical treatments provided in the NHS were ineffective, inefficient, and founded on medical opinion rather than on a rigorous assessment of efficacy and effectiveness. Box 7.1 defines the terms efficacy, effective, and efficiency.
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