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Journal articles on the topic 'Wide surgical excision'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Vandeweyer, E., N. De Saint Aubain Somerhausen, and M. Gebhart. "Dermatofibrosarcoma Protuberans: How Wide is Wide in Surgical Excision ?" Acta Chirurgica Belgica 102, no. 6 (2002): 455–58. http://dx.doi.org/10.1080/00015458.2002.11679351.

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2

Morinaga, Sei, Shinji Miwa, Norio Yamamoto, et al. "Clinical characteristics of patients with undergoing unplanned excisions of malignant soft tissue tumors." Journal of Orthopaedic Surgery 29, no. 3 (2021): 230949902110575. http://dx.doi.org/10.1177/23094990211057597.

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Introduction Malignant soft tissue tumors are rare tumors representing <1% of all malignancies. As these tumors are rare, it is not uncommon that malignant soft tissue tumor excision is performed without the required preoperative imaging, staging, or wide resection margins for sarcomas. The purpose of this study was to investigate the characteristics of patients with undergoing unplanned excisions. Risk factors for tumor recurrence and mortality in patients treated with unplanned excisions were also analyzed. Methods Forty-nine patients who underwent unplanned excision at other hospitals an

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3

Judge, Abigail C., and Amir H. Tahernia. "Hidradenitis Suppurativa: Radical Surgical Excisions with Staged Reconstructions: A Single-Surgeon Retrospective Review of 71 Patients." Advances in Skin & Wound Care 37, no. 11&12 (2024): 1–8. http://dx.doi.org/10.1097/asw.0000000000000237.

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ABSTRACT BACKGROUND Hidradenitis suppurativa is a chronic, inflammatory disease involving the pilosebaceous unit of apocrine gland-bearing skin. Wide surgical excision, wherein margins extend beyond active lesions, is considered curative. OBJECTIVE To evaluate the safety and efficacy of wide surgical excision in the treatment of hidradenitis suppurativa. METHODS This single-surgeon, single-site analysis included all patients undergoing radical surgical excision of hidradenitis suppurativa between 2015 and 2019. Using paper case notes and electronic health records, researchers identified a tota

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Al-Ani, Yahia Hameed, Raid M. Al-Ani, Wassan Nori, and Israa Mahdi Al-Sudani. "Recurrent Hidradenocarcinoma in the Abdominal Wall with no Distant Metastasis: A Case Report and Literature Review." Diyala Journal of Medicine 28, no. 1 (2025): 119–25. https://doi.org/10.26505/djm.v28i1.1181.

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Background: Hidradenocarcinoma is a rare, aggressive tumor with a high rate of local recurrence and distant metastasis. There are no current management guidelines, and surgery has been used to control the primary disease. Even with wide surgical excision, the course of the tumor is unpredictable, and the prognosis for survival is poor. The most common location is the scalp, followed by the extremities, and rarely the trunk. Objective: To present a rare recurrent hidradenocarcinoma in the abdominal wall with no distant metastasis. Case presentation: We present a rare case of recurrent hidradeno

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Gismalla, Mohamed. "Surgical treatment of mycetoma in a developing country; a systematic review and preliminary treatment algorithm guidelines." Rawal Medical Journal 50, no. 1 (2025): 1. https://doi.org/10.5455/rmj.20241108053200.

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Objective: To describe a framework for surgical excision of mycetoma based on the experiences reported in Sudanese studies. Methodology: This systematic retrieved relevant manuscripts, which were assessed, tabulated, and analyzed for patient demographics and surgical techniques employed. Results: Search yielded seven studies, including four observational hospital-based studies and three case reports, encompassing 2,009 patients. Wide surgical excision was the most common intervention performed in 880 patients, while amputations were necessary in 85 cases. Based on the reviewed data a prelimina

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Vivero, Richard J., and Soham Roy. "S255 – Treatment of Complicated and Uncomplicated Preauricular Pits." Otolaryngology–Head and Neck Surgery 139, no. 2_suppl (2008): P160. http://dx.doi.org/10.1016/j.otohns.2008.05.431.

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Objectives 1) To review our experience with complicated and uncomplicated preauricular pits requiring surgical excision. 2) To review relevant embryology, anatomy, and surgical technique. Methods A retrospective chart review from 2002 to 2007 was conducted at a tertiary care university hospital to identify patients less than 18 years old undergoing surgical excision of a preauricular pit. Charts were reviewed for patient age, presentation, complications, treatment algorithm, and outcome. Results 13 patients underwent surgical excision of a preauricular pit. The indication for excision was eith

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Bilden, Tylert, Katherine C. Benedict, Patrick W. Lamb, and Jaron Mcmullin. "Intraoperative Frozen Section Analysis for the Excision of Nonmelanoma Skin Cancer: A Single-Center Experience." American Surgeon 85, no. 12 (2019): 1397–401. http://dx.doi.org/10.1177/000313481908501236.

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Surgical resection of nonmelanoma skin cancer (NMSC) may be performed via Mohs micrographic surgery (MMS) or standard surgical excision with complete margin analysis. Whereas MMS may necessitate delayed reconstruction surgery, intraoperative frozen section analysis (IFSA) may be used to ensure clear surgical margins before proceeding with reconstruction. To achieve curative resection while optimizing aesthetic outcomes, surgeons may use surgical excision guided by IFSA to forego extensive or delayed reconstruction. Patients undergoing wide local excision for NMSC using IFSA from October 2008 t

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8

Ikram, A. Arramach, Bouali S., Rhaouti M., et al. "Wide Local Excision for Dermatofibrosarcoma Protuberans: A Surgical Approach." Medical Science Research Bulletin 02, no. 05 (2025): 36–39. https://doi.org/10.5281/zenodo.15412771.

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<strong>Introduction</strong>: Darier and Ferrand dermatofibrosarcoma is a locally malignant soft-tissue sarcoma with a high recurrence rate and rare metastasis, first described in 1924. <strong>Results: </strong>This retrospective study analyzes 20 cases of chest wall dermatofibrosarcoma treated at Hassan II University Hospital in Fez from 2009 to 2023. The median patient age was 44.95 years, with a slight female predominance. Tumors varied in size and presentation, commonly appearing as multi-nodular or ulcerating masses. Histological analysis showed spindle-shaped cells with CD34 expre

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Sinha, Dr J. K., and Dr K. K. Mangal. "Reconstruction Of Extensor Apparatus Of Knee By Gracilis." Indian Journal of Plastic Surgery 24, no. 01 (1991): 020–22. http://dx.doi.org/10.1055/s-0043-1774664.

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AbstractMarginal excision, wide excision with radieal resection, hip disarticulation and hemipelvectomy are the operative modalities in vogue for the surgical management of lower extremity sarcomas. Leiomyosarcoma of lower one third of thigh is treated by wide excision and resultant defect is filled by gracilis transposition technique.

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10

Pickett, Laura E., and Jillian Macdonald. "Injectable Diphenhydramine Used as Anaesthetic for Wide Local Excision With Flap Closure." Journal of Cutaneous Medicine and Surgery 21, no. 3 (2016): 256–57. http://dx.doi.org/10.1177/1203475416681760.

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Background: Lidocaine-allergic patients pose a challenge for cutaneous surgical procedures. We present a case of a successful wide local excision with flap closures on the face using topical tetracaine followed by infiltration with 1% diphenhydramine. Case Summary: An 84-year-old woman, with a lidocaine intolerance, presented to the Mohs surgery clinic for wide local excision of a nodular basal cell carcinoma on her right medial cheek. Successful anaesthesia was achieved using topical 4% tetracaine followed by intradermal and subcutaneous injection of 1% diphenhydramine. Haemostasis was achiev

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11

Samkoe, Kimberley S., Brent D. Bates, Jonathan T. Elliott, et al. "Application of Fluorescence-Guided Surgery to Subsurface Cancers Requiring Wide Local Excision." Cancer Control 25, no. 1 (2018): 107327481775233. http://dx.doi.org/10.1177/1073274817752332.

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The excision of tumors by wide local excision is challenging because the mass must be removed entirely without ever viewing it directly. Positive margin rates in sarcoma resection remain in the range of 20% to 35% and are associated with increased recurrence and decreased survival. Fluorescence-guided surgery (FGS) may improve surgical accuracy and has been utilized in other surgical specialties. ABY-029, an anti-epidermal growth factor receptor Affibody molecule covalently bound to the near-infrared fluorophore IRDye 800CW, is an excellent candidate for future FGS applications in sarcoma rese

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12

MacGill, Alan A., Vincent R. Milione, and Laura G. Sullivan. "Extra-abdominal Desmoid Fibromatosis in the Foot." Journal of the American Podiatric Medical Association 101, no. 1 (2011): 70–74. http://dx.doi.org/10.7547/1010070.

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Extra-abdominal desmoid tumors account for 0.03% of all neoplasms and rarely present in the foot. They are benign but locally aggressive, and wide local surgical excision is the treatment of choice owing to the high rate of recurrence in the lower extremities. Invasiveness into the surrounding soft-tissue structures often makes wide excision difficult without compromise of function. We describe a 34-year-old woman with a large, pedal, extra-abdominal desmoid fibroma treated by wide local surgical excision with minimal complications postoperatively and no clinical evidence of recurrence at 28 m

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Om Prakash Palsania, Rajneesh Galwa, Garima Choudhary, Narender Singh, and Sunil Kumar Meena. "A comparative study between wide local excision with lay open versus Limberg flap transposition in the management of pilonidal sinus disease – A single center study." Asian Journal of Medical Sciences 14, no. 10 (2023): 251–57. http://dx.doi.org/10.3126/ajms.v14i10.55335.

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Background: Pilonidal sinus disease (PSD) is a tract in the sacrococcygeal region’s subcutaneous tissue that presents with recurrent infection and persistent inflammation. The best surgical strategy for treating pilonidal sinus illness is still up for debate, despite the fact that several surgical techniques for treating the sacrococcygeal pilonidal sinus have been identified. Aims and Objectives: This study evaluated several intraoperative and post-operative constraints related to the surgical techniques of wide excision with lay open and Limberg flap transposition for treating pilonidal sinu

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Morinaga, Sei, Norio Yamamoto, Katsuhiro Hayashi, et al. "Clinical outcomes and life expectancy of patients with unplanned excisions of soft tissue sarcoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e23554-e23554. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e23554.

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e23554 Background: As soft tissue sarcomas are rare, it is not uncommon that soft tissue sarcoma excision is performed without the required preoperative imaging, staging, or wide resection margins for sarcomas. This study investigated the characteristics of unplanned excision and analyzed the recurrence, life expectancy, and proper treatment for unplanned excision. Methods: Patients who underwent unplanned excision at another institution followed by additional wide excision at our hospital from January 2002 to December 2018 were identified. Forty-two patients met our criteria. The relationship

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15

McArthur, Grant A. "Molecular Targeting of Dermatofibrosarcoma Protuberans: A New Approach to a Surgical Disease." Journal of the National Comprehensive Cancer Network 5, no. 5 (2007): 557–62. http://dx.doi.org/10.6004/jnccn.2007.0049.

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Dermatofibrosarcoma protuberans (DFSP) is a low-grade malignancy of the skin and subcutaneous tissues that only rarely forms distant metastases. More than 90% of cases are associated with a chromosomal translocation involving the COL1A1 gene on chromosome 17 and the platelet-derived growth factor B gene on chromosome 22. Management of this disease is primarily surgical with excellent rates of local control obtained using either wide local excision or Mohs micrographic surgery. Data have recently shown that inhibiting platelet-derived growth factor receptors (PDGFR) with imatinib can induce hig

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Emeršič, Luka, Albin Stritar, and Vesna Jurčić. "Malignant pilomatrixoma case report: what kind of treatment is the most suitable?" International Journal of Research in Dermatology 9, no. 1 (2022): 32. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20223342.

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<p class="abstract">Malignant pilomatrixoma is a rare malignancy with just 136 cases reported in the English literature. The tumour is described as locally aggressive, with possibility of reoccurrence and distal metastasis. Histology remains the gold standard in diagnostic. Wide surgical excision is preferred to simple excision. In the present study a case of first malignant pilomatrixoma in our hospital is described. We made an excision of the tumour and the tissue was sent on histopathology. The skin defect was covered with a local ulnar flap. Through our case report and literature rev

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17

Giuliano, A. E., and F. R. Eilber. "The rationale for planned reoperation after unplanned total excision of soft-tissue sarcomas." Journal of Clinical Oncology 3, no. 10 (1985): 1344–48. http://dx.doi.org/10.1200/jco.1985.3.10.1344.

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Multimodality management of soft-tissue sarcomas of the extremity is often based on the presence or absence of residual primary disease. Reoperation is warranted or radiotherapy doses altered if the physician is aware that the tumor was incompletely excised. Most patients with soft-tissue masses undergo an initial excision before definitive therapy. These initial unplanned total excisions are usually excisional biopsies for presumably benign disease. Ninety patients were reviewed to evaluate the adequacy of unplanned total excision. All patients underwent unplanned supposed total excisions. Mo

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18

Su, Chin-Horng, Jui-Kuo Hung, and Ing-Lin Chang. "Surgical Treatment of Intramuscular, Infiltrating Lipoma." International Surgery 96, no. 1 (2011): 56–59. http://dx.doi.org/10.9738/1396.1.

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Abstract Lipoma may occasionally be found within the muscle, which is the intramuscular, infiltrating lipoma. Intramuscular, infiltrating lipoma is an uncommon lesion, and local recurrence can be expected if the surgical margin is not clear. We report 8 patients in a 2-year period diagnosed with intramuscular, infiltrating lipoma who were treated by marginal excision combined with wide excision in the Department of Orthopaedic Surgery, Changhua Christian Hospital. The surgical results were satisfactory, and no local recurrence was noted in an average follow-up period of 40 months. Surgical exc

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P. B., Thrishuli, and Akshata Kamath B. "Granulomatous mastitis-a challenging surgical entity." International Surgery Journal 4, no. 6 (2017): 2077. http://dx.doi.org/10.18203/2349-2902.isj20172052.

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Background: Idiopathic granulomatous mastitis is a rare benign breast disease, first described by Kessler and Wolloch in 1972. It is characterized by chronic necrotizing granulomatous lobulitis of unknown aetiology. The objective of the study is to find out the clinical and management profile of granulomatous mastitis (GM). This study was carried out at JSS hospital, Mysore, Karnataka, India during the period 2014-2016.Methods: Histopathologically diagnosed cases of GM were studied. Data included, detailed history, examination, clinical diagnosis, ultrasound, mammogram and fine needle aspirati

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20

Akakpo, Kenneth, Kaylee Luck, and Robert H. Chun. "Use of a Cervicofacial Flap in Closing Large Defects Following Wide Local Excision of Complicated Preauricular Lesions." Annals of Otology, Rhinology & Laryngology 129, no. 12 (2020): 1163–67. http://dx.doi.org/10.1177/0003489420932605.

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Purpose: To describe innovative surgical technique for closure of large defect following complicated preauricular cyst excision secondary to prior failed excision attempts, infections, and drainage procedures. Preauricular cysts must be widely excised including any fistulous tracts in order to reduce recurrence rates; however, the resultant large local excision poses cosmetic challenges. Methods: Retrospective chart review of 3 patient cases who underwent excision of recurrent preauricular lesions involving cervical parotid flap closure. All three cases demonstrate complicated preauricular con

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Islami, Egi Ghilman, and Yuhantoro Budi Handoyo Sakti. "Wide Excision of a Giant Lipoma of The Upper Arm: A Case Report." Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan 6, no. 1 (2023): 1. http://dx.doi.org/10.30595/hmj.v6i1.17239.

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A lipoma is the most typical mesenchymal tumor. Over time, lipomas can grow into substantial masses. Case, A 71-year-old woman complained of a mass in her upper right arm but reported no pain or discomfort. The mass is 13 x 11 x 6 cm in size. Histopathological analysis and a wide excision surgical approach were used. A mass more than 5 cm in diameter is considered a giant lipoma. A differential diagnosis of liposarcoma can be made using a computed tomography (CT) scan or magnetic resonance imaging (MRI). The two surgical procedures of wide and marginal excision are typically used to treat lipo

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Herman, Bjorn S., and Simon I. Angeli. "Wide Decompression of Facial Neuromas: An Alternative to Surgical Excision." Laryngoscope 119, S1 (2009): S116. http://dx.doi.org/10.1002/lary.20410.

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23

Dellaportas, Dionysios, Thomas Kotsis, Eleni Carvounis, and Lazaros Samanides. "Leiomyoma of the Greater Saphenous Vein Mimicking Inguinal Lymphadenopathy." Case Reports in Surgery 2013 (2013): 1–2. http://dx.doi.org/10.1155/2013/237391.

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Introduction. Leiomyoma is a benign vascular tumor affecting the greater saphenous vein rarely. Proper histopathological examination sets the diagnosis after complete and wide surgical excision along with a normal portion of the GSV.Case Presentation. A 36-year-old woman was admitted to our hospital complaining of a dull ache on her right groin for the last three months, along with a palpable mass on the mentioned area. An ultrasound (U/S) scan revealed a solid mass measuring3×2 cm. After wide surgical excision, pathological examination revealed a leiomyoma of the GSV.Discussion. Benign and mo

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Shanmugam, Subbiah, and Radha Siva Bharath C. H. "Chondrosarcoma of the anterior chest wall: surgical resection and reconstruction, our institutional experience." International Journal of Research in Orthopaedics 9, no. 4 (2023): 796–99. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20232003.

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Primary chest wall tumours are not very common. Chondrosarcomas is most common tumour arising from the chest wall. It occurs more often during the third and fourth decade of life. Chondrosarcomas are resistant to conventional chemotherapy and radiotherapy. Wide margin surgical excision remains the best available treatment approach. For chondrosarcomas involving the chest wall, surgical excision may result in chest wall defects that may require reconstruction to obliterate dead space, restore chest wall rigidity, preserve respiratory mechanics, maintain pulmonary function, protect intrathoracic

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Cristea, Şt, R. Popescu, Şt Cuculici, et al. "Resection Reconstruction Versus Amputation in the Treatment of Malignant Tumors of the Limbs." Romanian Journal of Orthopaedic Surgery and Traumatology 1, Supplement (2018): 60. http://dx.doi.org/10.2478/rojost-2018-0071.

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Abstract Partial or complete excision of the tumoral segment with preservation of the limb extremity in the treatment of tumors is an alternative to amputation. We present our cases with radical or wide resection and reconstruction with or without special prosthesis reconstruction. We used an evaluation and prognosis score, which included surgical stage, site of tumor, size of tumor, surgical margin, functional mobility, and activity level after surgery. Excision of the tumor with a wide margin, stable reconstruction and a good recovery is an alternative treatment to the amputation.

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Singh, Nilanchali, Sivalakshmi Ramu, Ruchi Rathore, Divya Sehra, and Jyoti Meena. "Wide Local Excision versus Simple Vulvectomy in Vulval Intraepithelial Neoplasia 3: Case Report and Literature Review." Journal of Colposcopy and Lower Genital Tract Pathology 2, no. 1 (2024): 35–38. http://dx.doi.org/10.4103/jclgtp.jclgtp_4_24.

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Vulvar intraepithelial neoplasia is a premalignant lesion of the vulva. Women with vulvar cervical intraepithelial neoplasia 3 are at high risk of recurrence and vulvar carcinoma. They warrant a surgical management for the same reason. It may be either ablative or excisional, sometimes can be a combination of both. The decision for wide local excision or simple vulvectomy depends on clinical factors. Case: We present a case of a 67-year-old lady who presented with vulvar itching and a large black vulvar lesion involving the fourchette area, with HPV 16 positive. Initially, there was a doubt of

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Morris, J., G. T. Royle, and I. Taylor. "Changes in the Surgical Management of Early Breast Cancer in England." Journal of the Royal Society of Medicine 82, no. 1 (1989): 12–14. http://dx.doi.org/10.1177/014107688908200105.

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A questionnaire survey of consultant surgeons in England indicates that there has been a considerable change in opinion over the past few years concerning the management of early breast cancer; only 39.1% would now perform mastectomy, whereas 64.4% would perform conservative surgery. The most common forms of management are simple mastectomy and axillary clearance (21.9%); wide excision, axillary clearance plus radiotherapy (20.1%); and wide excision plus radiotherapy alone (16.9%). The majority of the surgeons would offer patients a choice of surgery, but only 52% had access to a breast care n

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Thakur, JS, NK Mohindroo, and DR Sharma. "Forehead Flap for Nasal Reconstruction." An International Journal Clinical Rhinology 3, no. 1 (2010): 13–15. http://dx.doi.org/10.5005/jp-journals-10013-1019.

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Abstract Cancers and granulomatous diseases cause wide spread destruction of nose and reconstruction is a challenge to the surgeon. majority of the surgical defects after BCC excision can be reconstructed by full thickness skin grafts, bilobed and rhomboid local flaps but excision of SCC and large BCC lead to large surgical defects which need regional or distant flaps for reconstruction like median forehead flaps.

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Ehrhart, Nicole. "Soft-Tissue Sarcomas in Dogs: A Review." Journal of the American Animal Hospital Association 41, no. 4 (2005): 241–46. http://dx.doi.org/10.5326/0410241.

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Soft-tissue sarcomas are a heterogeneous group of tumors with similar biological behaviors. Wide surgical excision remains the cornerstone of treatment for these tumors. Local recurrence is common following conservative resection, and recurrent tumors are more difficult to treat. Radiation therapy or re-excision with wider margins is indicated if excision is microscopically incomplete. Chemotherapy is often recommended as an adjunctive treatment for high-grade soft-tissue sarcomas because of their higher metastasis rates when compared to low-or intermediate-grade soft-tissue sarcomas. Knowledg

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Pulec, Jack L. "Aggressive Fibromatosis (Fibrosarcoma) of the Facial Nerve." Ear, Nose & Throat Journal 72, no. 7 (1993): 460–72. http://dx.doi.org/10.1177/014556139307200703.

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Aggressive fibromatosis of the facial nerve is a very rare tumor. Three cases have been previously reported. The tumor is locally recurrent and often has a fatal outcome. This report is of a ten-year-old boy whose tumor originally developed in the parotid area with subsequent spread to the base of the skull, the neck and the cerebellopontine angle. Treatment was by wide surgical excision, radiation therapy and chemotherapy. Despite treatment, the patient died. The clinical features of this case will be described. Only wide surgical excision early in the course of the disease may offer a chance

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Kikuchi, N., T. Nakashima, J. Fukushima, K. Nariyama, and S. Komune. "Well-differentiated liposarcoma arising in the parapharyngeal space: a case report and review of the literature." Journal of Laryngology & Otology 129, S2 (2015): S86—S90. http://dx.doi.org/10.1017/s0022215114002461.

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AbstractBackground:Liposarcomas rarely occur in the parapharyngeal space and only a few case reports exist. For curative therapy of liposarcoma, surgical excision remains the dominant modality. Although a wide surgical margin is important to prevent local recurrence, wide excision is often difficult in the head and neck region.Case report:We report a case of a 19-year-old female with a well-differentiated liposarcoma arising in the parapharyngeal space. We removed the tumour surgically utilising a cervical–parotid approach. The histological diagnosis was well-differentiated sclerosing liposarc

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Friedman, Erica B., Tristan J. Dodds, Serigne Lo, et al. "Correlation Between Surgical and Histologic Margins in Melanoma Wide Excision Specimens." Annals of Surgical Oncology 26, no. 1 (2018): 25–32. http://dx.doi.org/10.1245/s10434-018-6858-y.

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Turcu, E. G. "Surgical Treatment Option in a Recurrent Giant Sacrococcygeal and Gluteal Squamous Cell Carcinoma - Case Presentation." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 07 (2024): 614–17. https://doi.org/10.5281/zenodo.12771696.

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This article refers to the case of a 57-year-old female patient admitted in our clinic for a recurrent giant sacrococcygeal and gluteal squamous cell carcinoma.In the past, excisional biopsy was performed in another clinic of plastic surgery, followed by tumor excision,chemotherapy and radiotherapy for 6 months.After one year, the patient addresses our clinic for giant tumor recurrence in the sacrococcian region and bilateral buttocks. The MRI examination carried out highlights a tumor formation that invades both gluteal regions up to the level of the piriformis muscle and the sacrum. No metas

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Taniguchi, Y., T. Tamaki, M. Yoshida, and Y. Uematsu. "Reconstruction of a Scalp and Skull Defect with Free Latissimus Dorsi Myocutaneous Flap following Dermatofibrosarcoma Protuberans." Journal of Orthopaedic Surgery 10, no. 2 (2002): 206–9. http://dx.doi.org/10.1177/230949900201000217.

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A 53-year-old male underwent more than 10 surgical treatments over 14 years, including a simple excision and local flap transfer, after recurrences of dermatofibrosarcoma protuberans of the head. Clinical results indicated that simple excision of dermatofibrosarcoma protuberans should not be performed as initial treatment. Instead, free flap transplantation, which permits a wide excision and complete reconstruction, should be the first treatment option.

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Hsieh, Patrick C., Khan W. Li, Daniel M. Sciubba, Ian Suk, Jean-Paul Wolinsky, and Ziya L. Gokaslan. "Posterior-Only Approach For Total En Bloc Spondylectomy For Malignant Primary Spinal Neoplasms: Anatomic Considerations and Operative Nuances." Operative Neurosurgery 65, suppl_6 (2009): ons173—ons181. http://dx.doi.org/10.1227/01.neu.0000345630.47344.17.

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Abstract MALIGNANT PRIMARY SPINAL tumors are rare tumors that are locally invasive and can metastasize. The majority of these tumors have a poor response rate to chemotherapy and conventional radiotherapy. Studies have shown that long-term survival and the potential for cure is best achieved with en bloc surgical excision of these tumors with negative surgical margins. Total en bloc spondylectomy involves removal of vertebral segment(s) in whole to achieve wide tumor excision. Total en bloc spondylectomy can be performed through staged or combined anterior and posterior approaches, or from a p

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Kumar, Dinesh, Md Sahil Reza, Sushovon Das, and Utpal De. "From Benign Beginning to Malignant Giant: The Journey of Recurrent Cystosarcoma Phyllodes." NATIONAL BOARD OF EXAMINATIONS JOURNAL OF MEDICAL SCIENCES 3, no. 2 (2025): 232–35. https://doi.org/10.61770/nbejms.2025.v03.i02.011.

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A 42-year-old lady presented with a recurrent left breast mass, initially diagnosed as a benign phyllodes tumor. Despite wide local excision, the tumor recurred thrice over three years, each recurrence demonstrating increasing stromal cellularity and atypia. Imaging revealed a giant heterogeneous mass, and core biopsy confirmed a borderline phyllodes tumor. Surgical management included a wide local excision of the mass and chest wall with immediate reconstruction. Histopathology showed malignant transformation with negative margins. Postoperative recovery was uneventful. This case highlights t

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Rajgopal, Vandhana, Saugata Sammader, Piyush Ranjan, and Mohammed Fawaz. "Phyllodes tumour presenting in a rare location: a case report and literature review." International Surgery Journal 9, no. 8 (2022): 1500. http://dx.doi.org/10.18203/2349-2902.isj20221910.

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Phyllodes tumors are rare fibro-epithelial tumors that are known to grow very rapidly in a short period. The tumor is known for its propensity to recur locally despite adequate wide excisions and even mastectomies. This case report is of a woman who had a recurrent Phyllodes tumor in a peculiar location. Phyllodes tumours are generally confined to arising from the breast; however, in this case, we found it arising from the anterior abdominal wall. The tumour was removed with a 2 cm margin of excision. The large defect that remained after excision was reconstructed using a latissimus dorsi flap

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Hamid, Raashid, Aadil Hafeez, Ashraf M. Darzi, Inam Zaroo, Habib Owais, and Afrozah Akhter. "Dermatofibrosarcoma protuberans: Role of wide local excision." South Asian Journal of Cancer 02, no. 04 (2013): 232–38. http://dx.doi.org/10.4103/2278-330x.119926.

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Abstract Objectives: The main objective of the present study was to study the outcome of surgical treatment of dermatofibrosarcoma protuberans. Materials and Methods: This study included 45 patients both retrospective and prospective from December 1995 to December 2010. Results: Out of 45 patients, 30 were males and 15 females with the male to female ratio of 2:1. Mean age of presentation was 38.4 + 13.2 years. Commonest mode of presentation was raised firm multinodular lesion with fixity to overlying skin. Site distribution was 42.22% trunk, 57.88% extremities and head and neck. None of the p

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Wijeratne, YMTY, HDKC Hapuachchige, and S. Kannangara. "A Rare Case Series of Vaginal Melanoma- experience of National Cancer Institute Sri Lanka." Asian Pacific Journal of Cancer Care 7, no. 2 (2022): 409–13. http://dx.doi.org/10.31557/apjcc.2022.7.2.409-413.

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Vaginal melanomas are extremely rare gynaecological malignancy with aggressive behavior resulting in poor outcome. The aetiology is not well understood so far. There is no standardized treatment owing to the extreme rarity of the disease, however surgical excision with adjuvant radiotherapy has been the widely practiced treatment. The role of lymphadenectomy is controversial. The six cases reported between November 2015 to November 2021 at the National cancer institute Sri Lanka were treated primarily by surgical excision including hysterocolpectomy, colpectomy, and wide local excision. Pelvic

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Alam, Afroza E., Nusrat Shaheed, Mahabuba Khatun, Mohammed Rashed Uz Zaman, Nazneen Akter, and Md Abul Hosen. "Outcome of Wide Local Excision in Idiopathic Granulomatous Mastitis-A Short Observational Study." Central Medical College Journal 8, no. 1 (2024): 35–37. https://doi.org/10.3329/cemecj.v8i1.78030.

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Background: Idiopathic granulomatous mastitis is a rare disease of the breast. It is a benign inflammatory lesion characterized by lobulocentric granulomas. Clinically and radiologically it may mimic breast carcinoma.1 Awareness of surgeons, pathologists, and radiologists is essential to avoid unnecessary mastectomies. Objective: This study aimed to investigate the outcome of wide local excision in idiopathic granulomatous mastitis. Method: This hospital based prospective study was done in surgery unit of both govt. and private hospitals, Cumilla, Bangladesh. All patients who were diagnosed wi

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Seale, Karen S., Thomas A. Lange, David Monson, and Donald A. Hackbarth. "Soft Tissue Tumors of the Foot and Ankle." Foot & Ankle 9, no. 1 (1988): 19–27. http://dx.doi.org/10.1177/107110078800900105.

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Seven patients with malignant soft tissue tumors of the foot and ankle were retrospectively reviewed. Emphasis was placed on the value of various diagnostic modalities used preoperatively for staging and the adequacy of treatment rendered using current tumor surgery principles. The malignant tumors included synovial cell sarcoma (four), clear cell sarcoma (one), fibrosarcoma (one), and melanoma (one). Surgical management of the malignant lesions included intracapsular excision, marginal excision, wide excision, and radical amputation.

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Adil, Dehhaze, Mai Aicha, Barij Hamza, et al. "Dermatofibrosarcoma of Darrier and Ferrand: Recurrency Character: A Case-Report (Experience of the University Hospital Tangier-Tetouan-Al Hoceima)." Scholars Journal of Medical Case Reports 12, no. 04 (2024): 610–14. http://dx.doi.org/10.36347/sjmcr.2024.v12i05.009.

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Introduction: Dermatofibrosarcoma of Darier and Ferrand (DFSP) is a rare skin tumor characterized by its local aggressiveness and high potential. Its prognosis depends essentially on the quality of its management. Observation and Results: In this article, we report the case of a young patient treated at the Department of Plastic, Reconstructive and Aesthetic Surgery, Tangier, for a Darier and Ferrand dermatofibrosarcoma that recurred five times after surgical excision, with a 5-cm margin on the surface and a healthy anatomical barrier at depth. Coverage of the loss of substance (LOS) was perfo

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Rose, Kyle M., Rosalie Zurlo, Roger Li, Gerard Mosiello, and Philippe E. Spiess. "Oncologic Outcomes of a Novel Mapping Biopsy Technique Before Surgical Excision in the Management of Extramammary Paget Disease." Société Internationale d’Urologie Journal 4, no. 1 (2023): 34–38. http://dx.doi.org/10.48083/lcme5237.

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Objective To analyze oncologic outcomes of patients with extramammary Paget disease (EMPD) undergoing a novel mapping biopsy before tumor excision (WLE). Methods We analyzed 19 consecutive patients with EMPD treated with biopsy and/or surgical excision at Moffitt Cancer Center from 2013 to 2021. Biopsy technique, patient demographics, pathology, and oncologic outcomes were analyzed. Results In total, 19 patients were included in the analysis. Median age at diagnosis was 72. No patients were diagnosed with secondary malignancy during mandatory workup. Of the 17 patients receiving novel mapping

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Kim, Yung Hoon, and Joseph Kyu-hyung Park. "Skin-Sparing Marginal Excision: Case Report of a Novel Approach to Dystrophic Calcification." Journal of Wound Management and Research 19, no. 3 (2023): 210–14. http://dx.doi.org/10.22467/jwmr.2023.02635.

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Dystrophic calcification (DC) is a rare manifestation of calcium salt accumulation in non-skeletal tissues, often associated with local tissue damage. This case report presents a 45-year-old female patient who manifested soft-tissue calcification in an extra-articular burn scar, developing after a substantial latency period of 40 years. The conventional treatment, wide excision with skin grafting, was declined by the patient due to cosmetic and socioeconomic reasons. Instead, a skin-sparing marginal excision was performed. A thorough removal of the calcified lesions were achieved while conserv

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Akram, Muhammad Usman, Hafsa Atique, Saad Siddiqui, Sohaib Haider, Ahmed Raza, and Naveed Arshad. "Management of a giant carbuncle on the posterior trunk with excision and grafting." Journal of the Pakistan Medical Association 71, no. 11 (2021): 2665–68. http://dx.doi.org/10.47391/jpma.011651.

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Carbuncle is a painful subcutaneous mass of infected hair follicles with a purulent discharge. It has predisposition in conditions like diabetes, immune-compromised states, chronic skin diseases etc. The authors present a case of a 67 year old diabetic male with a giant carbuncle on his back. Due to its large size, systemic co-morbidity and increased risk of complications in surgical treatment, a multi-disciplinary team approach was employed. Both general and plastic surgery were involved, who performed excision and soft tissue coverage respectively. Aim of the surgical intervention methods, l

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Vulovic, Dejan, Vesna Stankovic, Tatjana Sarenac-Vulovic, et al. "Giant exophytic Marjolin's ulcer of the lower leg after the gunshot wound: Case report." Vojnosanitetski pregled, no. 00 (2021): 11. http://dx.doi.org/10.2298/vsp201110011v.

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Introduction. Marjolin's ulcer is a skin malignancy that occurs on a scar or chronic wound. It most commonly occurs on a burn scar. Squamous cell carcinoma is the most common type of tumor, in more than 90% of cases. The rate of this rare malignant transformation is 1-2%. Marjolin's ulcer is more aggressive than other skin cancers. Wide excision is the treatment of choice. Recurrences are common. The aim of this article is to present a large exophytic carcinoma of the lower leg as a rare form of this tumor according to the size and type. The result of the radical surgery with reconstruction is

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Sylla, S., O. E. Atiqui, C. E. Fifatin, et al. "Degeneration of Verneuil Disease into Squamous Cell Carcinoma: About 4 Cases." SAS Journal of Surgery 09, no. 09 (2023): 705–12. http://dx.doi.org/10.36347/sasjs.2023.v09i09.002.

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Hidrosadenitis suppurativa, or Verneuil's disease, is quite common, especially in men in our context, but is often unrecognized. Degeneration of Verneuil's disease into squamous cell carcinoma remains the most dreaded complication. Clinical manifestations include painful and inflammatory nodular lesions evolving chronically towards suppuration and fistulization in areas bearing apocrine glands. The most frequent localization in our context was in the gluteal and/or intergluteal area, and the diagnostic method remains biopsy. Treatment is multidisciplinary, both medical and surgical: above all,

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Lucandri, Giorgio, Paolo Mazzocchi, Bruno Bascone, et al. "Unusual Ulcerated Merkel Cell Carcinoma of the Skin: Report of a Case." Tumori Journal 92, no. 6 (2006): 555–58. http://dx.doi.org/10.1177/030089160609200618.

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Merkel cell carcinoma is an aggressive skin cancer, usually related to a severe prognosis. Treatment consists of wide surgical excision, adjuvant radiotherapy and/or polychemotherapy, but local-regional and distant relapses are common. Detection of histopathological and biological factors may select subgroups of patients suitable for different treatments. Herein we report the case of a patient treated for a wide bleeding and ulcerated Merkel cell carcinoma. Ulceration represents an uncommon feature because the tumor usually spreads from the dermis into subcutaneous fat, so it may be added to p

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Ah Lee, Seung, Allison C. Hu, and Gregory R. D. Evans. "Impact of Immediate Surgical Reconstruction Following Wide Local Excision of Malignant Melanoma." Plastic and Reconstructive Surgery - Global Open 7 (August 2019): 65. http://dx.doi.org/10.1097/01.gox.0000584584.50444.f4.

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B, Dembélé,, Diarra, H, Daou, A, et al. "Giant Hip Lipoma with Physical and Psychological Impact at Bamako Dermatology Hospital." EAS Journal of Medicine and Surgery 6, no. 03 (2024): 115–18. http://dx.doi.org/10.36349/easjms.2024.v06i03.006.

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Giant lipomas are voluminous benign mesenchymal tumors formed by fatty lobules from mature adipose tissue and whose exact etiological is not yet elucidated. We report the case of a 64-year-old patient with a giant lipoma at the hip with physical and psychological impact. Treatment was surgical and consisted of a wide excision of the mass. The surgical piece measured 378X303 mm and weighed 2600 grams. The surgical follow-ups were simple. The late management of lipomas can lead them to reach an inordinate size causing disabilities and increasing the possibility of neoplastic transformation. Afte

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