Relevant bibliographies by topics / William Buckley / Journal articles
To see the other types of publications on this topic, follow the link: William Buckley.

Journal articles on the topic 'William Buckley'

Author: Grafiati
Published: 10 January 2023
Last updated: 28 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'William Buckley.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Grimshaw, James A., and Mark Royden Winchell. "William F. Buckley, Jr." South Central Review 2, no. 2 (1985): 103. http://dx.doi.org/10.2307/3189156.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

University, Linfield. "The Great Debate." James Baldwin Review 6, no. 1 (September 29, 2020): 13–27. http://dx.doi.org/10.7227/jbr.6.2.

Full text
Abstract:
Born in New York City only fifteen months apart, the Harlem-raised James Baldwin and the privileged William F. Buckley, Jr. could not have been more different, but they both rose to the height of American intellectual life during the civil rights movement. By the time they met in February 1965 to debate race and the American Dream at the Cambridge Union, Buckley—a founding father of the American conservative movement—was determined to sound the alarm about a man he considered an “eloquent menace.” For his part, Baldwin viewed Buckley as a deluded reactionary whose popularity revealed the sickness of the American soul. The stage was set for an epic confrontation that pitted Baldwin’s call for a moral revolution in race relations against Buckley’s unabashed elitism and implicit commitment to white supremacy. In this article I introduce readers to the story at the heart of my new book about Baldwin and Buckley, The Fire Is Upon Us.
APA, Harvard, Vancouver, ISO, and other styles
3

Lee, Michael J. "WFB: The Gladiatorial Style and the Politics of Provocation." Rhetoric and Public Affairs 13, no. 2 (June 1, 2010): 43–76. http://dx.doi.org/10.2307/41940492.

Full text
Abstract:
Abstract William F. Buckley afforded conservatives of all stripes a provocative rhetorical style, a gladiatorial style, as I term it. The gladiatorial style is a flashy combative style whose ultimate aim is the creation of inflammatory drama. I claim that conservatives encountered Buckley’s potent arguments about God, government, and markets and the gladiatorial style simultaneously. The theatrical appeal of Buckley’s gladiatorial style inspired conservative imitators with disparate beliefs and, over several decades, became one of the principal rhetorical templates for the performance of conservatism.
APA, Harvard, Vancouver, ISO, and other styles
4

Peacock, Amanda. "Reflections and Shadows: Picturing William ‘Murrangurk’ Buckley." Australian and New Zealand Journal of Art 13, no. 1 (January 2013): 50–69. http://dx.doi.org/10.1080/14434318.2013.11432642.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Meagher, Michael E. "Bogus, Carl T. Buckley: William F. Buckley Jr. and the Rise of American Conservatism." Journal of Interdisciplinary Studies 25, no. 1 (2013): 181–82. http://dx.doi.org/10.5840/jis2013251/211.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Whaley, Gray H. "William Clark: Indian Diplomat by Jay H. Buckley." Oregon Historical Quarterly 110, no. 1 (2009): 145–48. http://dx.doi.org/10.1353/ohq.2009.0027.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

McClure, Daniel Robert. "Possessing History and American Innocence: James Baldwin, William F. Buckley, Jr., and the 1965 Cambridge Debate." James Baldwin Review 2, no. 1 (December 13, 2016): 49–74. http://dx.doi.org/10.7227/jbr.2.4.

Full text
Abstract:
The 1965 debate at Cambridge University between James Baldwin and William F. Buckley, Jr., posed the question: “Has the American Dream been achieved at the Expense of the American Negro?” Within the contours of the debate, Baldwin and Buckley wrestled with the ghosts of settler colonialism and slavery in a nation founded on freedom and equality. Framing the debate within the longue durée, this essay examines the deep cultural currents related to the American racial paradox at the height of the Civil Rights movement. Underscoring the changing language of white resistance against black civil rights, the essay argues that the Baldwin and Buckley debate anticipated the ways the U.S. would address racial inequality in the aftermath of the civil rights era and the dawn of neoliberalism in the 1970s.
APA, Harvard, Vancouver, ISO, and other styles
8

Lowndes, Joseph. "William F. Buckley Jr.: Anti-blackness as Anti-democracy." American Political Thought 6, no. 4 (November 2017): 632–40. http://dx.doi.org/10.1086/694557.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Barndt, Will. "William F. Buckley Jr. and America’s “Engines of Concern”." American Political Thought 6, no. 4 (November 2017): 648–56. http://dx.doi.org/10.1086/694559.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Glaude, Eddie S. "Epilogue: William F. Buckley Jr. and James Baldwin Today." American Political Thought 6, no. 4 (November 2017): 665–70. http://dx.doi.org/10.1086/694560.

Full text
APA, Harvard, Vancouver, ISO, and other styles
11

Kamp, Allen. "Vertical Flip." Texas Wesleyan Law Review 13, no. 2 (March 2007): 729–36. http://dx.doi.org/10.37419/twlr.v13.i2.19.

Full text
Abstract:
This article grew out of my ongoing attempt to understand conservative ideology. Thinking about the topic for the 2006 Gloucester conference, I remembered William F. Buckley, Jr.'s Up from Liberalism (1959) and simultaneously thought of a function on my Adobe Photoshop, the "Flip." (The "Flip" produces a mirror image of your photo, either vertically or horizontally.) It struck me that Buckley's Up from Liberalism equated liberalism with slavery. In it, he describes the conservative as a slave to liberal hegemony: liberal society is an "engine for the imposition of liberal orthodoxy." In an essay," Why Don't We Complain," (1961, reprinted in Miles Gone By), he describes the situation of the American citizen as one of helplessness...
APA, Harvard, Vancouver, ISO, and other styles
12

Sarchett, Barry W. "Unreading the Spy Thriller: The Example of William F. Buckley, Jr." Journal of Popular Culture 26, no. 2 (September 1992): 127–39. http://dx.doi.org/10.1111/j.0022-3840.1992.2602127.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
13

Conn, Steven. "Forum: Thoughts on National Service An Open Letter to William F. Buckley, Jr." Change: The Magazine of Higher Learning 23, no. 3 (June 1, 1991): 6–52. http://dx.doi.org/10.1080/00091383.1991.9937686.

Full text
APA, Harvard, Vancouver, ISO, and other styles
14

CURTIS, JESSE. "“Will the Jungle Take Over?” National Review and the Defense of Western Civilization in the Era of Civil Rights and African Decolonization." Journal of American Studies 53, no. 4 (May 9, 2018): 997–1023. http://dx.doi.org/10.1017/s0021875818000488.

Full text
Abstract:
During the 1950s and 1960s, conservative intellectuals in the United States described African decolonization and the civil rights movement as symptoms of a global threat to white, Western civilization. In the most influential conservative journal of the period, National Review, writers such as William F. Buckley grouped these events together as dangerous contributors to civilizational decline. In the crucible of transnational black revolt, some conservative intellectuals embraced scientific racism in the 1960s. These often-ignored features of conservative intellectual thought provided space for white supremacist ideals to continue to ferment on the American right into the twenty-first century.
APA, Harvard, Vancouver, ISO, and other styles
15

Appel, Edward C. "Burlesque drama as a rhetorical genre: The hudibrastic ridicule of William F. Buckley, Jr." Western Journal of Communication 60, no. 3 (September 1996): 269–84. http://dx.doi.org/10.1080/10570319609374547.

Full text
APA, Harvard, Vancouver, ISO, and other styles
16

Sousa, Rodrigo Farias de. "National Review, o moderno conservadorismo americano e a luta para "salvar" os EUA do comunismo, do liberalismo e da integração racial (1955-1959)." Revista de História, no. 180 (March 25, 2021): 1–31. http://dx.doi.org/10.11606/issn.2316-9141.rh.2021.167096.

Full text
Abstract:
O movimento conhecido como moderno conservadorismo americano toma forma na década de 1950 com pelo menos dois objetivos primordiais: no plano externo, combater a ameaça representada pelo comunismo internacional e, no plano doméstico, subverter a dominância exercida pelo liberalismo do New Deal, cuja influência no governo, na sociedade e na cultura fragilizaria a posição dos EUA na Guerra Fria e poria em risco os melhores valores nacionais. Este artigo examina algumas das premissas desse conservadorismo tomando como amostragem a revista National Review, fundada por William F. Buckley Jr. Em particular, analisa-se como a publicação abordou o fim da segregação racial nas escolas públicas, determinada pela Suprema Corte dos Estados Unidos em 1954.
APA, Harvard, Vancouver, ISO, and other styles
17

Bedsole, Nathan Henry. "Voice as little object (a)rgument: on hearing Gore Vidal and William F. Buckley Jr." Argumentation and Advocacy 54, no. 4 (October 2, 2018): 323–39. http://dx.doi.org/10.1080/10511431.2018.1509594.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

NEMETH, JULIAN. "The Passion of William F. Buckley: Academic Freedom, Conspiratorial Conservatism, and the Rise of the Postwar Right." Journal of American Studies 54, no. 2 (December 4, 2018): 323–50. http://dx.doi.org/10.1017/s0021875818001469.

Full text
Abstract:
In the early years of the Cold War, as universities expelled scholars with ties to the Communist Party, it became an article of faith among conservatives that the only targets of an ideological purge were people like themselves. William F. Buckley's God and Man at Yale, the most important exponent of this view, argued that “academic freedom” was a “superstition” designed to promote liberal indoctrination. Buckley's work tweaked, and mainstreamed, claims that a subversive conspiracy had overtaken the nation's schools and colleges. The correspondence the book generated demonstrates how attacks on academic freedom, and claims of victimhood, mobilized the postwar right.
APA, Harvard, Vancouver, ISO, and other styles
19

Cox, John K. "William Joseph Buckley, ed., Kosovo: Contending Voices on Balkan Interventions. Grand Rapids, MI: William B. Eerdmans, 2000, xix, 528 pp. + 5 maps." Nationalities Papers 29, no. 3 (September 2001): 533–35. http://dx.doi.org/10.1017/s0090599200020110.

Full text
APA, Harvard, Vancouver, ISO, and other styles
20

Bernatsky, Zoe. "Taking Sides: Clashing Views in Death and Dying ed. by William J. Buckley and Karen S. Feldt." Journal of the Society of Christian Ethics 36, no. 1 (2016): 214–15. http://dx.doi.org/10.1353/sce.2016.0004.

Full text
APA, Harvard, Vancouver, ISO, and other styles
21

Gvosdev, N. K. "Kosovo: Contending Voices on Balkan Interventions. Edited by William Joseph Buckley. Grand Rapids, Mich.: William B. Eerdmans Publishing Company, 2000. 528 pp. $30.00 cloth." Journal of Church and State 43, no. 1 (January 1, 2001): 144–45. http://dx.doi.org/10.1093/jcs/43.1.144.

Full text
APA, Harvard, Vancouver, ISO, and other styles
22

Miller, Reuben Jonathan, Janice Williams Miller, Jelena Zeleskov Djoric, and Desmond Patton. "Baldwin’s Mill." Humanity & Society 39, no. 4 (October 27, 2015): 456–75. http://dx.doi.org/10.1177/0160597615609188.

Full text
Abstract:
Written in the 50th anniversary of the historic debate between author and social critic James Baldwin and the “father of American conservatism” William F. Buckley, we extract from the corpus of Baldwin’s social critique a method to grasp emergent forms of marginality in the contemporary age. Described as a mill, Baldwin shows how everyday interactions shaped the behaviors and meaning making of black Americans during the civil rights era, teaching them to repress their feelings, motivations, and desires at the threat of violence. Inspired by Baldwin, we apply this analytic to mass imprisonment and the rise of prisoner reentry as a national policy priority. Attending to the “work” of reentry in the lives of the black poor, we find that the institutional and policy arrangements that gave birth to prisoner reentry, coupled with the exclusion of the criminalized poor from full participation in the social, civic, and economic life of the city operates as a pedagogy, locating the presumed black and criminalized poor within a social hierarchy and situating them within a moral taxonomy.
APA, Harvard, Vancouver, ISO, and other styles
23

Hale, Frederick. "Before the Eradication of God: the Yoruba Smallpox Deity Shonponna in t m aLuko's One Man, One Wife." Religion and Theology 9, no. 3-4 (2002): 266–81. http://dx.doi.org/10.1163/157430102x00142.

Full text
Abstract:
AbstractThe Yoruba deity Shonponna, feared as both the bearer of smallpox and the one to whom one could turn for protection therefrom, has been the subject of sporadic international, scholarly enquiry for more than a century. William Bascom, Anthony D. Buckley and others went well beyond late nineteenth-century British colonial observations in their attempts to understand the enduring appeal of this dreaded deity, the banning of whose worship in Nigeria did not prevent adherents from crossing into Benin to continue it. In his novel of 1959, One man, one wife, Yoruba novelist and public health authority Timothy Mofolorunso Aluko offered an internal perspective by illuminating further dimensions of the place of Shonponna in the rapidly changing religious matrix of western Nigeria. This account features a plot that unfolds in the 1920s and 1930s, when Anglican missionaries were adding an increasingly prominent and influe.tial factor to the scene, and therein exploring the confrontation of traditional religious beliefs and practices with Christianity, partly during a smallpox epidemic which intensifies the clash of these two systems.
APA, Harvard, Vancouver, ISO, and other styles
24

Gaston, K. H. "The Cold War Romance of Religious Authenticity: Will Herberg, William F. Buckley Jr., and the Rise of the New Right." Journal of American History 99, no. 4 (February 15, 2013): 1133–58. http://dx.doi.org/10.1093/jahist/jas588.

Full text
APA, Harvard, Vancouver, ISO, and other styles
25

Popielec, Dominika. "Cybergenic Presidential Candidates of Third Parties in the United States: The Analysis of Selected Political Campaigns with the Key Role of New Media." Kwartalnik Kolegium Ekonomiczno-Społecznego. Studia i Prace, no. 4 (December 26, 2017): 97–116. http://dx.doi.org/10.33119/kkessip.2017.4.5.

Full text
Abstract:
This article focuses on selected political campaigns of the Third Parties in the United States. The main purpose of this work is to present how these candidates promote themselves and communicate with voters. Traditional and new media are playing a crucial role in public life during presidential elections. Not only do they inform society but also are a tool of political communication. Voters can get to know a candidate and his/her election program via the media. Journalists are conducting interviews with main candidates, especially the Democrats and Republicans, which are leaders in the polls. But what should the candidates from other parties do? Those who do not appear very often in the mainstream media? How do they gain public support for their ideas? Do we insist on a telegenic president, as William F. Buckley indicated, or a cybergenic president in the contemporary world? Considering the increasing role of the Internet in modern society, these candidates use new new media to promote themselves. Therefore, in this article I will describe the importance of new media, their effectiveness in presidential campaigns and a cybergenic candidate as a standard of modern political communication
APA, Harvard, Vancouver, ISO, and other styles
26

Lebron, Christopher. "Equality from a Human Point of View." Critical Philosophy of Race 2, no. 2 (August 1, 2014): 125–59. http://dx.doi.org/10.5325/critphilrace.2.2.125.

Full text
Abstract:
Abstract Racial inequality remains a persistent feature of American life. Despite the prominent place the idea of equality holds in the tradition of political philosophy, we remain without an effective conception appropriate for the experience of racial inequality. In this paper, I re-frame debates around equality and egalitarianism by reflecting on some of James Baldwin's more strident arguments in his 1965 debate with William Buckley. I suggest he presses two complaints that are fundamental to racial inequality: the complaints of democratic distance and of disaffection. I then argue that while contemporary egalitarian theorists such as G. A. Cohen, Ronald Dworkin, Richard Arneson, and Elizabeth Anderson all claim to have isolated in their work a preferred conception of equality, they are unable to respond to Baldwin's complaints, thus unable to effectively address the experience of racial inequality. I then leverage Bernard Williams's distinction between a technological view of equality and a human view alongside his writing on imagination to offer a framework for meeting the moral demands that arise from taking the experience of racial inequality as fundamental to considerations over social and political equality.
APA, Harvard, Vancouver, ISO, and other styles
27

Schryer, Stephen. "The Fire Is Upon Us: James Baldwin, William F. Buckley Jr., and the Debate over Race in America by Nicholas Buccola." African American Review 53, no. 2 (2020): 148–50. http://dx.doi.org/10.1353/afa.2020.0022.

Full text
APA, Harvard, Vancouver, ISO, and other styles
28

Vargas, Carlos. "The Racial Nightmare and the Genteel Racism." Revista Portuguesa de Ciência Política / Portuguese Journal of Political Science, no. 15 (2021): 129–36. http://dx.doi.org/10.33167/2184-2078.rpcp2021.15/pp.129-136.

Full text
APA, Harvard, Vancouver, ISO, and other styles
29

Ostler, J. "William Clark: Indian Diplomat. By Jay H. Buckley. (Norman: University of Oklahoma Press, 2008. xx, 306 pp. $29.95, ISBN 978-0-8061-3911-1.)." Journal of American History 95, no. 4 (March 1, 2009): 1148–49. http://dx.doi.org/10.2307/27694596.

Full text
APA, Harvard, Vancouver, ISO, and other styles
30

Bennett, Nolan. "Nicholas Buccola: The Fire Is upon Us: James Baldwin, William F. Buckley Jr., and the Debate over Race in America. (Princeton: Princeton University Press, 2019. Pp. xii, 482.)." Review of Politics 82, no. 4 (2020): 642–44. http://dx.doi.org/10.1017/s0034670520000479.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

BURNS, JENNIFER. "GODLESS CAPITALISM: AYN RAND AND THE CONSERVATIVE MOVEMENT." Modern Intellectual History 1, no. 3 (October 21, 2004): 359–85. http://dx.doi.org/10.1017/s1479244304000216.

Full text
Abstract:
This essay examines the relationship between the novelist/philosopher Ayn Rand (The Fountainhead, Atlas Shrugged) and the broader conservative movement in the twentieth-century United States. Although Rand was often dismissed as a lightweight popularizer, her works of radical individualism advanced bold arguments about the moral status of capitalism, and thus touched upon a core issue of conservative identity. Because Rand represented such a forthright pro-capitalist position, her career highlights the shifting fortunes of capitalism on the right. In the 1940s, she was an inspiration to those who struggled against the New Deal and hoped to bring about a new, market-friendly political order. As a second generation of conservatives built upon these sentiments and attempted to tie them to a defense of Christian tradition, Rand's status began to erode. Yet by the late 1960s, Rand's once-revolutionary defense of capitalism had become routine, although she herself remained a controversial figure. The essay traces the ways in which Rand's ideas were assimilated and modified by key intellectuals on the right, including William F. Buckley, Jr, Whittaker Chambers, and Gary Wills. It identifies the relationship between capitalism and Christianity as a fundamental dilemma for conservative and right-wing thinkers. By treating Rand as an intellectual and cultural leader of significant import, the essay broadens our understanding of the American right beyond the confines of “mainstream” conservatism, and re-establishes the primacy of the 1930s, and 1940s, to its ideological formation. Responding to a paucity of scholarship on Rand, the essay offers an analysis and summary of Rand's ideas, and argues that despite her outsider status, Rand's work both embodied and shaped fundamental themes of right-wing thought throughout the century.
APA, Harvard, Vancouver, ISO, and other styles
32

BRICK, HOWARD. "ACHIEVING THE AMERICAN SOUL." Modern Intellectual History 14, no. 2 (October 19, 2016): 619–29. http://dx.doi.org/10.1017/s1479244316000354.

Full text
Abstract:
In 1963—as good a date as any to serve as a pivot between “fifties” and “sixties” America—James Baldwin remarked, “The American Negro has the great advantage of having never believed the collection of myths to which white Americans cling: that their ancestors were all freedom-loving heroes, that they were born in the greatest country the world has ever seen, or that Americans are invincible in battle and wise in peace.” It was a bracing declaration, a bit gentler than Malcolm X's designation of Negroes as “victims of Americanism” and perhaps by now, as historians focus ever greater attention on the nationally constitutive role of slavery and white supremacy, almost a commonplace. Yet Baldwin's idea remains challenging to plumb and to fully inhabit. For at that moment, which both Kevin Schultz and Andrew Hartman suggest was preoccupied with “the very question of America and its meaning,” Baldwin's little book, The Fire Next Time, upended the whole debate. He was no black nationalist and, notwithstanding his expatriate life in France, no “emigrationist,” for he believed that blacks in the United States were, socially and culturally, wholly of, if not in, this country; and yet, given the deep corruption in the national past, there was no “meaning” to return to, reclaim, realize, or vindicate as a promise of black freedom. The verb Baldwin chose, in a determinedly existentialist vein, was to “achieve our country”—to create a viable moral meaning for national identity where none as yet existed. If Schultz's subjects, William F. Buckley Jr, and Norman Mailer, were “vying for the soul of the nation” and Hartman's warriors fighting “for the soul of America,” they were—in Baldwin's perspective—chasing a chimera. Such a thing wasn't there; it was yet to come, if at all.
APA, Harvard, Vancouver, ISO, and other styles
33

Wichert, Sabine. "The Northern Ireland Conflict: New Wine in Old Bottles?" Contemporary European History 9, no. 2 (July 2000): 307–22. http://dx.doi.org/10.1017/s0960777300002095.

Full text
Abstract:
James Loughlin, The Ulster Question since 1945 (London: Macmillan, 1998), 151 pp., £10.99 (pb), ISBN 0–333–60616–7.David Harkness, Ireland in the Twentieth Century. Divided Island (London: Macmillan, 1996), 190 pp., £9.99 (pb), ISBN 0–333–56796–X.Thomas Hennessey, A History of Northern Ireland, 1920–1996 (London: Macmillan, 1997), 347 pp., £12.99 (pb), £40.00 (hb), ISBN 0–333–73162–X.Brian A. Follis, A State Under Siege. The Establishment of Northern Ireland, 1920–1925 (Oxford: Clarendon, 1995), 250 pp., £35.00 (hb), ISBN 0–198–20305–5.Dermot Keogh and Michael H. Haltzel, eds., Northern Ireland and the Politics of reconciliation (Cambridge: Cambridge University Press, 1994), 256 pp., £35.00 (hb), ISBN 0–521–44430–6.William Crotty and David Schmitt, eds., Ireland and the Politics of Change (London/New York: Longman, 1999), 264 pp., £17.99 (pb), ISBN 0–582–32894–2.David Miller, ed., Rethinking Northern Ireland. Culture, Ideology and Colonialism. (London/New York: Longman, 1999), 344 pp., £17.99 (pb), ISBN 0–582–30287–0.Anthony D. Buckley and Mary Catherine Kenney, Negotiating Identity: Rhetoric, Metaphor, and Social Identity in Northern Ireland (Washington: Smithonian Institution Press, 1996), 270 pp., £34.75 (hb), ISBN 1–560–98520–8.John D. Brewer, with Gareth I. Higgins, Anti-Catholicism in Northern Ireland, 1600–1998: the mote and the beam (London: Macmillan, 1998), 248 pp., £16.99 (pb), ISBN 0–333–74635–X.During the last three decades, and accompanying the ‘troubles’, the literature on Northern Ireland has mushroomed. Within the last ten years two surveys have attempted to summarise and categorise the major interpretations. John Whyte's Interpreting Northern Ireland covered the 1970s and 1980s and came to the conclusion that traditional Unionist and nationalist interpretations, with their emphasis on external, that is British and Irish, forces as the cause for the problem, had begun to lose out to ‘internal conflict’ interpretations. He felt, however, that this approach, too, was coming to the end of its usefulness, and he expected the emergence of a new paradigm shortly.
APA, Harvard, Vancouver, ISO, and other styles
34

KITLV, Redactie. "Book Reviews." New West Indian Guide / Nieuwe West-Indische Gids 61, no. 1-2 (January 1, 1987): 55–114. http://dx.doi.org/10.1163/13822373-90002056.

Full text
Abstract:
-Sidney W. Mintz, Mats Lundahl, The Haitian economy: man, land and markets. New York: St. Martins Press, 1983. 290 pp.-Regine Altagrace Latortue, Léon-Francois Hoffmann, Essays on Haitian Literature. Washington D.C.: Three Continents Press, 1984. 184 pp.-Robert Forster, Lieutenant Howard, The Haitian journal of lieutenant Howard, York Hussars, 1796-1798. Edited with an introduction by Roger Norman Buckley. Knoxville: University of Tennessee Press, 1985. liv + 194.-David Bray, Bernardo Vega, Los Estados Unidos y Trujillo, año 1930. Santo Domingo: Fundación Cultural Dominicano, 1986. 2 vols. xi + 1120 pp.-David Bray, Bernardo Vega, Los Estados Unidos y Trujillo, año 1947. Santo Domingo: Fundación Cultural Dominicana, 1984. 2 vols. xi + 1018 pp.-David Bray, Bernardo Vega, Nazismo, fascismo y falangismo en la Republica Dominicana. Santo Domingo: Fundación Cultural Dominicana, 1985. 415 pp.-Tony Thorndike, Bruce J. Calder, The impact of intervention: The Dominican Republic during the US occupation of 1916-1924. Austin: University of Texas Press, 1984. 358 pp.-Marcella M. Little, Jacques Barbier ,The North American role in the Spanish imperial economy 1760-1819. Manchester, England, 1984: Manchester University Press. pp. 232., Allan J. Kuethe (eds)-Janette Forte, Peter Riviere, Individual and society in Guiana: a comparative study of Amerindian social organisation. Cambridge, London, New York: Cambridge University Press, 1984. 127 pp.-Stephen D. Glazier, Jay D. Dobbin, The Jombee dance of Montserrat: a study of trance ritual in the West Indies. Columbus: Ohio State University Press, 1986. 202 pp.-Robert J. Stewart, Stephen D. Glazier, Marchin' the Pilgrims home: leadership and decision-making in an Afro-Caribbean faith. Connecticut and London: Greenwood Press, 1983. xv + 165 pp.-Sidney M. Greenfield, Karen Fog Olwig, Cultural adaptation and resistance on St. John: three centuries of Afro-Caribbean life. Gainesville: University of Florida Press, 1985. xii + 226 pp.-Adam Kendon, William Washabaugh, Five fingers for survival. Ann Arbor: Karoma Publishers, Inc., 1986. xiv + 198 pp.-Evelyne T. Menard, Carnot (F. Moloen), Alors ma chére...Propos d'un musicien guadeloupéen recueillis et traduits par Marie-Céline Lafontaine. Paris: Editions Caribéennes, 1986. 159 pp.-Sally Price, Suzanne Slesin ,Caribbean style. Authors include Daniel Rozensztroch. Photographs by Gilles de Chabaneix. New York: Clarkson N. Potter, 1985. 290 pp., Stafford Cliff, Jack Berthelot (eds)-Allison Blakely, Gert Oostindie ,In het land van de overheerser. Deel II. Antillianen en Surinamers in Nederland, 1634/1667-1954. Dordrecht (Holland) and Providence RI (U.S.A.): Foris Publications, 1986. xi + 255 pp., Emy Maduro (eds)-Rosemarijn Hoefte, E. van de Boogaart ,Overzee: Nederlandse koloniale geschiedenis, 1590-1975. Haarlem: Fibula-van Dishoek, 1982. 291 pp., P.J. Drooglever et al (eds)-Frederick J. Conway, P.I. Gomes, Rural development in the Caribbean. London: C. Hurst and Company. New York: St. Martins Press, 1985. xxi + 246 pp.-Steve M. Slaby, Charles Edquist, Capitalism, socialism and technology: a comparative study of Cuba and Jamaica. London: Zed Books Ltd., 1985. xiii + 182 pp.-Joan D. Mandle, June Nash ,Women and social change in Latin America. South Hadley, Mass.: Bergin and Garvey Publishers, 1986. 372 pp., Helen Safa (eds)-Bonham C. Richardson, Michael L. Conniff, Black labor on a white canal: Panama, 1904-1981. Pittsburgh, Pa.: University of Pittsburgh Press, 1985. xv + 221 pp.-Brackette F. Williams, Stephen Glazier, Caribbean ethnicity revisited. A special edition of Ethnic Groups, International periodical of ethnic studies. New York, London, Paris, Montreaux, Tokyo: Gordon Breach Science Publishers, 1985. 164 pp.-Gert J. Oostindie, Frauke Gewecke, Die Karibik; zur Geschichte, Politik und Kultur einer Region. Frankfurt/M: Verlag Klaus Dieter Vervuert 1984. 165 pp.
APA, Harvard, Vancouver, ISO, and other styles
35

Hammond, Joseph. "William S. Bucklin and George P. Bartle: Accomplished Artists of Phalanx, New Jersey." New Jersey Studies: An Interdisciplinary Journal 7, no. 2 (July 22, 2021): 188–200. http://dx.doi.org/10.14713/njs.v7i2.256.

Full text
Abstract:
This narrative describes the lives and artistic careers of William Savery Bucklin (1851–1928) and George Parker Bartle (1853–1918), both of Phalanx, a hamlet in Colts Neck, Monmouth County, New Jersey. Three of the works illustrated come from the art collection of the Monmouth County Park System. They acquired them because the paintings depict woodland scenes on the opposite side of the Swimming River Reservoir from their Thompson Park campus, the back areas of which still retain this wooded character.
APA, Harvard, Vancouver, ISO, and other styles
36

Cass, Philip. "REVIEW: Noted: Documentary exposes dark side of Tongan diaspora." Pacific Journalism Review : Te Koakoa 25, no. 1&2 (July 31, 2019): 314. http://dx.doi.org/10.24135/pjr.v25i1and2.497.

Full text
Abstract:
Gangsters in Paradise—The Deportees of Tonga. Documentary. 2019. Director: Ursula Williams. Vice/Zealandia.‘IT’S LIKE crabs being stuck in a bucket scratching each other to get out.’‘It’s like rubbish dumping.’Those are two views about the crisis facing Tonga as countries like the United States, Australia and New Zealand deport criminals to the kingdom.
APA, Harvard, Vancouver, ISO, and other styles
37

Hogeland, William. "William Buckley’s Legacy in the Politics of Denial and the Denial of Politics." American Political Thought 6, no. 4 (November 2017): 657–64. http://dx.doi.org/10.1086/694565.

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Arista, Noelani. "Navigating Uncharted Oceans of Meaning: Kaona as Historical and Interpretive Method." PMLA/Publications of the Modern Language Association of America 125, no. 3 (May 2010): 663–69. http://dx.doi.org/10.1632/pmla.2010.125.3.663.

Full text
Abstract:
I ka ‘ōlelo nō ke ola, I ka ‘ōlelo nō ka make. In speech there is life, in speech death.—Hawaiian proverb ('ōlelo no'eau)“With You is My Life, with You My Death.” With these Words, the American Missionary Rev. William Richards Placed Himself Under the protection of the ‘aha’ ōlelo, a Hawaiian chiefly council composed of the highest-ranking ali'i in the Sandwich Islands. On the afternoon of 26 November 1827, Richards defended himself before the ‘aha against a charge of libel brought by the English consul, Richard Charlton. Charlton had argued with Richards over a letter the minister had written to his Boston-based employers, the American Board of Commissioners for Foreign Missions (ABCFM). The letter, written in October 1825, contained the news that an English captain, William Buckle, had purchased a Hawaiian woman from a chiefess. The problem was not the letter itself but the fact that it had been made public, through American newspapers. It would take the news two years to make its way back to the islands from New England, a world two oceans and six months’ sail away. The purchase of the woman, according to Charlton, was slavery and constituted a violation of British piracy law (qtd. in Richards, Letter to Evarts, 6 Dec. 1827). When Richards refused to sign an oath swearing to the veracity of his letter, Charlton accused the missionary of libel. Now both parties had come before the ‘aha ‘ōlelo to argue their cases. The question before the chiefs was whether or not the American Richards should be turned over to Charlton to face the charge in front of an English jury.
APA, Harvard, Vancouver, ISO, and other styles
39

Abiodun Jacob, Osuntogun. "Delivery of Goods to Carriers in International Sales: An Examination of What It Purported to Be in Nigeria." Business Law Review 39, Issue 2 (April 1, 2018): 44–53. http://dx.doi.org/10.54648/bula2018010.

Full text
Abstract:
Summary This article deals with international sales. Specifically, it discusses the question of delivery of goods to the carrier and its implication that it shall be ‘prima facie deemed to be a delivery of the goods to the buyer’. The legal consequences in Nigeria of a contract entered into by parties of different origin with respect to delivery of goods to the carrier are examined. It further discusses how a breach of duties and obligations on the part of the parties can lead to the application of statutory exceptions. It notes that there are two international conventions ratified and domesticated in Nigeria, but one protects the interests of one party more than the other and the other also does the same with the interests of the other party. It considers the application of these international conventions on the issue of delivery of goods to the carrier. Furthermore, it also considers the application of Incoterms in Nigeria to carriage of goods and argues that the controversy generated in the United Kingdom by Vaughan Williams LJ and Buckley LJ, on the one hand, and Hamilton LJ, on the other hand, has reverberated to Nigeria. It points out a misconception in the application of law on this issue which has been accepted as a settled principle of law in Nigeria.
APA, Harvard, Vancouver, ISO, and other styles
40

MORAN, C. "High risk maternity nursing manual Edited by Kathleen Buckley and Nancy W. Kulb. Baltimore: Williams & Wilkins, 1990. 549 pages. $39.95, softcover." Journal of Nurse-Midwifery 37, no. 1 (January 1992): 67–68. http://dx.doi.org/10.1016/0091-2182(92)90028-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
41

Dooley, Allan C. "Revivifying Matthew Arnold: The Direction of Arnold StudiesThe Cultural Theory of Matthew Arnold. Joseph CarrollOn the Poetry of Matthew Arnold. William E. Buckler." Modern Philology 83, no. 1 (August 1985): 55–61. http://dx.doi.org/10.1086/391431.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

Szekely, Rachel. "The Linguistic Reflexes of Ontological Dependence." International Review of Pragmatics 7, no. 1 (2015): 1–21. http://dx.doi.org/10.1163/18773109-00701001.

Full text
Abstract:
Nouns used to pick out ontologically dependent entities such as holes and flaws, unlike those picking out “ordinary” entities, such as coats and tables, cannot felicitously stand as indefinite subjects of a locative copular sentence (#A hole is in the bucket), but appear freely in there-sentences (There is a hole in the bucket). This contrast is further evidence in favour of the idea that the two sentence types have different underlying predication structures (cf. Barwise and Cooper, 1981; Francez, 2007; Hazout, 2004; McNally 1998a; Williams, 1984, 1994), but also that the preposition in, occurring in both constructions, is ambiguous between a locative and relational meaning. That locative in is distinct from the in that relates a dependent entity to its host is confirmed by inferences between and among sentences containing these two forms. Locative in, whose meaning is roughly that of enclosure or containment, is licensed as a predicate in a locative copular sentence; this sentence type is used to state the location of an entity. However, because a dependent entity’s location is entirely contingent on its host, it cannot be felicitously introduced in this way. By contrast, it is possible to introduce a dependent entity by stating that its host has the dependent entity in it, which is what a there-sentence does. Following Hornstein, Uriagereka and Rosen (1994), the underlying representation of a there-sentence which realizes this relation does not contain a preposition; rather, relational in is derived via incorporation into the copula, like have (Kayne, 1993).
APA, Harvard, Vancouver, ISO, and other styles
43

Rosenthal, Debra J. "The White Blackbird: Miscegenation, Genre, and the Tragic Mulatta in Howells, Harper, and the "Babes of Romance"." Nineteenth-Century Literature 56, no. 4 (March 1, 2002): 495–517. http://dx.doi.org/10.1525/ncl.2002.56.4.495.

Full text
Abstract:
In this essay I construct a literary genealogy that situates William Dean Howells in the middle of a call-and-response literary conversation with popular women writers about race, gender, and genre. Since Howells correlated racial questions with realism, his only novel that treats intermarriage, An Imperative Duty (1891), offered Howells an opportunity to deploy his presumably objective, scientific, realist knowledge about race in order to challenge women's romantic miscegenation plots found in Margret Holmes Bates's The Chamber over the Gate (1886) and Alice Morris Buckner's Towards the Gulf (1887), two novels that he had recently read and reviewed. Yet the tragic mulatta stereotype, a stock figure of romanticism and sentimentality that was resistant to scientific discourse, ruptures Howells's goal of representing the figure according to the tenets of realism. In Iola Leroy (1892), Frances Ellen Watkins Harper cunningly recasts the tragic mulatta stereotype both to critique Howells's project and to represent the potential of black womanhood. Knowledge of Bates and Buckner can change critical conversation about the influence of women writers on Howells, the understanding of the role of the racialized woman in his fiction, and his conception of the link between the romantic mulatta and realist representation. Likewise, Harper takes issue with Howells's supposed ironic sophistication about race, and in Iola Leroy she rewrites many of his views in order to show the ways that miscegenation is at once a novelistic and a national problem.
APA, Harvard, Vancouver, ISO, and other styles
44

DUMBRELL, JOHN. "Examining Political Change and Presidential Power in the US." Journal of American Studies 38, no. 3 (December 2004): 489–95. http://dx.doi.org/10.1017/s002187580400876x.

Full text
Abstract:
H. W. Brands, The Strange Death of American Liberalism (New Haven and London: Yale University Press, paperback edition, 2003, £9.95). Pp. 200. ISBN 0 300 098 24 3.Michael J. Gerhardt, The Federal Appointments Process: A Constitutional and Historical Analysis (Durham NC and London: Duke University Press, revised and expanded paperback edition, 2003, £18.50). Pp. 406. ISBN 0 8223 3199 3.William G. Howell, Power without Persuasion: The Politics of Direct Presidential Action (Princeton NJ and Oxford: Princeton University Press, 2003, cloth £29.95, paper £12.95). Pp. 239. ISBN 0 691 10269, 0 691 10270 8.Drew Noble Lanier, Of Time and Judicial Behavior: United States Supreme Court Agenda – Setting and Decision-Making, 1888–1997 (Selinsgrove PA: Susquehanna University Press and London: Associated University Presses, 2003, $42.50). Pp. 276. ISBN 1 57591 067 5.Byron E. Shafer, The Two Majorities and the Puzzle of Modern American Politics (Lawrence: University Press of Kansas, 2003, cloth $35, paper $19.95). Pp. 356. ISBN 0 7006 1235 1, 0 7006 1236 X.One does not have to be an especially sophisticated philosopher of explanatory method to appreciate that, in explaining change in human affairs, much depends on the situation of and level of analysis adopted by the would-be explainer. Do the dots connect or are they mostly what they appear to be – just dots? Reality, according to Bertrand Russell's famous aphorism, is either a bowl of connected jelly or a bucket of disconnected shot. It all depends on the observer, who, of course, is also part of the reality being considered.
APA, Harvard, Vancouver, ISO, and other styles
45

Wilkins, Robert B., and Rex A. Yannis. "Relative Canalicular Tear Flow as Assessed by Dacryoscintigraphy. By William L. White, A. Tyrone Glover, Arthur B. Buckner, and Michael F. Hartshorne. Ophthalmology 1989; 96." Ophthalmic Plastic & Reconstructive Surgery 5, no. 4 (December 1989): 298. http://dx.doi.org/10.1097/00002341-198912000-00030.

Full text
APA, Harvard, Vancouver, ISO, and other styles
46

ROSS, IAN CAMPBELL. "Novels, Chapbooks, Folklore: the several lives of William Chaigneau’s Jack Connor, now Conyers; or, John Connor, alias Jack the Batchelor, the Famous Irish Bucker." Eighteenth-Century Ireland: Volume 30, Issue 1 30, no. 1 (January 1, 2015): 62–92. http://dx.doi.org/10.3828/eci.2015.6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
47

U.K., AKhil Rao, Athira Soman, Anuradha Yadav, Yashwant R., and Sucheth Sharat. "Comparison between Sniffing Position and 25 Degree Backup Position in View of Glottis During Direct Laryngoscopy and Intubation - A Study from Mangalore, Karnataka." Journal of Evidence Based Medicine and Healthcare 8, no. 41 (October 30, 2021): 3573–77. http://dx.doi.org/10.18410/jebmh/2021/647.

Full text
Abstract:
BACKGROUND Endotracheal intubation for the purpose of providing anaesthesia was first described by William Mc Ewan. Jackson1 stressed the importance of anterior flexion of the lower cervical spine, in addition to obvious extension of the atlanto-occipital joint. Sniffing position has been commonly advocated as a standard head positioning for direct laryngoscopy which is achieved by flexion of the neck on chest and extension of the head at the atlanto-occipital joint. Present study was designed to evaluate the glottis view and ease of intubation achieved with direct laryngoscopy in the sniffing position with that of 25 degree backup position in a study group of 100 patients divided in 2 groups of 50 each. METHODS This study is a controlled comparative study. Controlled trial in 50 consecutive patients in each group [Group I and Group II] was conducted on patients who underwent elective surgery under general anaesthesia. Inclusion Criteria - General anaesthesia with endotracheal intubation, Aged 18 to 60 years, American society of Anaesthesiologists (ASA) grades I and II. Exclusion Criteria - Patients with body mass index more than 30 kg/m2. 1. Bucked teeth. 2. Restricted neck movement. 3. Inter-incisor gap less than 35 mm. 4. Thyro-mental distance less than 6 mm. 5. Patients with risk of regurgitation and aspiration. 6. Pharyngeal pathology. 7. Limitation of anterior and posterior movement of mandible 8. Pregnant patients Groups wereGroup I – Sniffing position Group II– 25 degree back up position RESULTS The glottis visualization was assessed by Cormack Lehane grading which revealed that glottis view was better in 25 degree backup position than sniffing position. CONCLUSIONS In our prospective randomized study in a series of 50 patients undergoing general anaesthesia in SIMS & RC, intubation difficulty scale (IDS) score was better in 25 degree backup position than sniffing position. It implies glottis view is better in 25 degree backup position than sniffing position. KEYWORDS Sniffing Position, 25 Degree Backup Position, Laryngoscopy
APA, Harvard, Vancouver, ISO, and other styles
48

Turner, Mary. "Roger Norman Buckley, editor. The Haitian Journal of Lieutenant Howard, York Hussars, 1796-1798. Knoxville: University of Tennessee Press. 1985. Pp. liv, 194. $22.50. - Barbara L. Solow and Stanley L. Engerman. British Capitalism and Caribbean Slavery: The Legacy of Eric Williams. (Studies in Interdisciplinary History.) New York: Cambridge University Press. 1987. Pp. x, 345. $29.95." Albion 21, no. 3 (1989): 501–3. http://dx.doi.org/10.2307/4050105.

Full text
APA, Harvard, Vancouver, ISO, and other styles
49

Ai, R., D. Boyle, D. Hammaker, K. Deane, V. M. Holers, A. Matti, W. Robinson, et al. "OP0337 DIFFERENTIAL METHYLATION OF PERIPHERAL BLOOD ADAPTIVE IMMUNE CELLS IN INDIVIDUALS AT HIGH RISK FOR RA AND WITH EARLY RA COMPARED WITH CONTROLS IDENTIFIES PATHWAYS IMPORTANT IN TRANSITION TO ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 207.2–207. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2989.

Full text
Abstract:
Background:The “Targeting Immune Responses for Prevention of RA” (TIP-RA) collaboration studies individuals at high risk for developing RA because of serum anti-citrullinated protein antibody positivity in absence of arthritis, and is focused on defining how they transition from at-risk to classifiable disease. One potential mechanism is through alterations in epigenetics patterns in adaptive immune cells.Objectives:Previous studies showed that DNA methylation patterns of early RA (ERA) synoviocytes differ from long-standing RA, suggesting that abnormal methylation occurs early in synovium and evolves over time. To extend these observations, we performed a cross-sectional analysis in TIP-RA of DNA methylation signatures in peripheral blood cells in ERA, at-risk anti-CCP3+ individuals and demographically matched CCP- controls.Methods:Genomic DNA was isolated from two independent cohorts of CCP- (cohorts 1 and 2, respectively: B cell: n = 17/34; memory T cell: n = 21/34; and naïve T cell: n = 21/33), CCP3+ (B cell: n = 18/37; memory T cell: n = 20/36; and naïve T cell: n = 20/35), and CCP3+ ERA (B cell: n = 4/18; memory T cell: n = 5/18; and naïve T cell: n = 5/18) after separating PBMCs using antibodies and magnetic beads. Methylation was measured by Illumina Infinium MethylationEPIC chip. Differentially methylated loci (DMLs) were identified using Welch’s t-test and mapped to gene promoter regions to define DM genes (DMGs). Principal component analysis (PCA) was used to represent relationship among groups. Pathway analysis was applied by Reactome.Results:For the initial cohort, 1494, 1097 and 1330 DMLs were identified among CCP+, CCP- and ERA in B cells, memory T cells and naïve T cells, respectively. For the confirmatory cohort, 523, 793 and 548 DMLs were found in corresponding cell populations. The DML overlap between the 2 cohorts was highly significant (p= 2.48E-77). The DMLs were combined for both groups and corresponded to 411, 412, and 351 DMGs in B cells, memory T cells and naïve T cells. Of these, we found 246, 198 and 195 DMGs between CCP3+ and ERA in each peripheral blood cell population, respectively. PCA showed separation of CCP+, CCP- and ERA in each of the three blood cell types by DMLs (Fig. 1). DMGs were mapped to biological pathways to identify DM pathways. Although most were not significant, there were several highly significant differences comparing CCP+, ERA and CCP- in memory T cells involving pathways, including “Interferon gamma signaling” (FDR 7.48E-14), “PD-1 signaling” (FDR 8.71E-10), “Translocation of ZAP-70 to Immunological synapse” (FDR 4.75E-10), and “Phosphorylation of CD3 and TCR zeta chains” (FDR 8.71E-10).Figure 1.PCA shows the separation of CCP+, CCP- and ERA patients in memory T cells in confirmatory cohort.Conclusion:We identified reproducible methylation signatures of CCP-, CCP+, and ERA in peripheral blood B cells, memory T cells and naïve T cells in initial and confirmatory cohorts. The methylome of ERA also demonstrated a distinctive pattern from CCP+, indicating that progression to RA is accompanied by epigenetic remodeling, especially in T cell signaling and interferon responses. These signatures identify critical pathways in CCP positivity and classifiable RA and could provide the basis of novel interventions to prevent disease.Disclosure of Interests:Rizi Ai: None declared, David Boyle: None declared, Deepa Hammaker: None declared, Kevin Deane Grant/research support from: Janssen, Consultant of: Inova, ThermoFisher, Janseen, BMS and Microdrop, V. Michael Holers Grant/research support from: Janssen, Celgene, and BMS, Andre Matti: None declared, William Robinson: None declared, Jane Buckner Grant/research support from: Bristol-Myers Squibb, Janssen, Navin Rao Shareholder of: Janssen Pharmaceuticals, Employee of: Janssen Pharmaceuticals, Frederic Baribaud Shareholder of: Janssen Research & Development, LLC, Employee of: Janssen Research & Development, LLC, Alyssa Johnsen Employee of: Janssen, Sunil Nagpal Shareholder of: Janssen Pharmaceuticals, Employee of: Janssen Pharmaceuticals, Wei Wang: None declared, Gary Firestein Grant/research support from: Lilly, Janssen, Abbvie
APA, Harvard, Vancouver, ISO, and other styles
50

Polinski, K., E. Bemis, K. Demoruelle, J. Seifert, T. Crume, F. Yang, W. Robinson, et al. "SAT0596 ASSOCIATIONS BETWEEN CIRCULATING LIPID MEDIATORS AND INCIDENT INFLAMMATORY ARTHRITIS IN AN ANTI-CITRULLINATED PROTEIN ANTIBODY POSITIVE POPULATION." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1256.1–1256. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1884.

Full text
Abstract:
Background:Lipid mediators are endogenously derived from the metabolism of omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) and have important roles in promoting and resolving inflammation in the body (1). Epidemiological studies have shown higher omega-3 PUFA status to be associated with a lower risk of both autoimmunity and progression to inflammatory arthritis (IA) (2,3).Objectives:To determine the association of lipid mediators with progression from rheumatoid arthritis (RA)-related autoimmunity to inflammatory arthritis (IA).Methods:We conducted a prospective cohort study using data from the Studies of the Etiologies of Rheumatoid Arthritis (SERA). SERA enrolled first-degree relatives (FDRs) of individuals with RA (FDR cohort) and individuals who screened positive for RA-related autoantibodies at health fairs (screened cohort). We followed 133 anti-CCP3.1 positive participants, of which 29 developed IA (22 classified as RA by 2010 ACR/EULAR criteria). We quantified lipid mediators from stored plasma samples via liquid chromatography tandem mass spectrometry methods validated against the collection and storage methods used in the study. A priori, we selected 5S-HETE, 15S-HETE and 17S-HDHA because they are precursors to leukotrienes, Lipoxin A4 and Resolvin D series lipid mediators, respectively. We fit Cox proportional hazard models for each lipid mediator as a time-varying covariate. For lipid mediators significantly associated with progression to IA we then examined IL-1β, IL-6, IL-8 and TNF-α (Bio-Plex Pro™ assay) as potential mediators of this relationship.Results:Higher plasma 5S-HETE levels were associated with an increased risk of incident IA after adjusting for age at baseline, cohort (FDR or screened), and shared epitope (SE) status (Table 1). The models examining 15S-HETE and 17S-HDHA had the same trend but did not reach statistical significance. We did not find evidence that the association between 5S-HETE and IA risk was mediated by the tested pro-inflammatory cytokines, suggesting a direct role for this lipid mediator in conversion to IA.Table 1.Hazard ratios and 95% confidence intervals of lipid mediator concentrations associated with IA, n=29 IA casesLipid mediatorCrudeAdjustedb5S-HETE2.10 (1.12, 3.92)2.41 (1.43, 4.07)15S-HETE1.61 (0.88, 2.93)1.52 (0.87, 2.65)17-HDHAa1.59 (0.68, 3.74)1.61 (0.72, 3.56)adichotomized as <limit of detection (reference) or detectedbAdjusted for SE, age at baseline and cohortConclusion:In a prospective cohort of anti-CCP positive individuals, higher circulating levels of 5S-HETE, an important precursor to pro-inflammatory leukotrienes, was associated with subsequent IA. Our findings highlight the potential pathologic and prognostic significance of these PUFA metabolites in inflammatory processes in pre-RA populations.References:[1]Serhan CN. Pro-resolving lipid mediators are leads for resolution physiology. Nature. 2014;510(7503):92-101.[2]Gan RW, Bemis EA, Demoruelle MK, Striebich CC, Brake S, Feser ML, et al. The association between omega-3 fatty acid biomarkers and inflammatory arthritis in an anti-citrullinated protein antibody positive population. Rheumatology. 2017.[3]Gan RW, Young KA, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, et al. Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study. Rheumatology. 2016;55(2):367-76.Disclosure of Interests:Kristen Polinski: None declared, Elizabeth Bemis: None declared, Kristen Demoruelle Grant/research support from: Pfizer, Jennifer Seifert: None declared, Tessa Crume: None declared, Fan Yang: None declared, William Robinson: None declared, Michael Clare-Salzler: None declared, Kevin Deane Grant/research support from: Janssen, Consultant of: Inova, ThermoFisher, Janseen, BMS and Microdrop, Michael Holers Shareholder of: AdMIRx, Grant/research support from: AdMIRx, Pfizer, Janssen R&D, Consultant of: AdMIRx, Janssen R&D, Celgene, Bristol-Myers Squibb, Jill Norris Grant/research support from: Janssen R&D, Pfizer, Consultant of: Celgene, BMS
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the bibliographies on the topic 'William Buckley' for other source types:
Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography